Health effects of ingested fluoride [[electronic resource] /] / Subcommittee on Health Effects of Ingested Fluoride, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Health effects of ingested fluoride [[electronic resource] /] / Subcommittee on Health Effects of Ingested Fluoride, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1993 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina | 615.9/257312 |
| Altri autori (Persone) | WagnerBernard Meyer <1928-> |
| Soggetto topico |
Fluorides - Toxicology
Fluorides - Metabolism Fluorides - Physiological effect Water - Fluoridation - Health aspects |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-21133-4
9786610211333 0-309-59638-6 0-585-02872-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910455375103321 |
| Washington, D.C., : National Academy Press, 1993 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Health effects of ingested fluoride [[electronic resource] /] / Subcommittee on Health Effects of Ingested Fluoride, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Health effects of ingested fluoride [[electronic resource] /] / Subcommittee on Health Effects of Ingested Fluoride, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1993 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina | 615.9/257312 |
| Altri autori (Persone) | WagnerBernard Meyer <1928-> |
| Soggetto topico |
Fluorides - Toxicology
Fluorides - Metabolism Fluorides - Physiological effect Water - Fluoridation - Health aspects |
| ISBN |
1-280-21133-4
9786610211333 0-309-59638-6 0-585-02872-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778615203321 |
| Washington, D.C., : National Academy Press, 1993 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Health effects of ingested fluoride / / Subcommittee on Health Effects of Ingested Fluoride, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Health effects of ingested fluoride / / Subcommittee on Health Effects of Ingested Fluoride, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1993 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina | 615.9/257312 |
| Altri autori (Persone) | WagnerBernard Meyer <1928-> |
| Soggetto topico |
Fluorides - Toxicology
Fluorides - Metabolism Fluorides - Physiological effect Water - Fluoridation - Health aspects |
| ISBN |
9786610211333
9781280211331 1280211334 9780309596381 0309596386 9780585028729 0585028729 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Health Effects of Ingested Fluoride -- Copyright -- Preface -- Contents -- Health Effects of Ingested Fluoride -- Executive Summary -- INTRODUCTION -- INTAKE, METABOLISM, AND DISPOSITION OF FLUORIDE -- DENTAL FLUOROSIS -- FLUORIDE AND BONE FRACTURES -- EFFECTS OF FLUORIDE ON THE RENAL SYSTEM -- EFFECTS OF FLUORIDE ON THE GASTROINTESTINAL SYSTEM -- EFFECTS OF FLUORIDE ON HYPERSENSITIVITY AND THE IMMUNE SYSTEM -- EFFECTS OF FLUORIDE ON REPRODUCTION -- GENOTOXICITY -- CARCINOGENICITY -- CONCLUSIONS -- Health Effects of Ingested Fluoride -- 1 Introduction -- 2 Dental Fluorosis -- THE FLUORIDE CONTENT OF TEETH -- FLUORIDE'S ACTION IN PREVENTING DENTAL CARIES -- HISTOPATHOLOGY OF DENTAL FLUOROSIS -- DIAGNOSTIC ISSUES IN DENTAL FLUOROSIS -- INDEXES FOR DENTAL FLUOROSIS -- DENTAL FLUOROSIS AND FLUORIDE INTAKE -- PREVALENCE OF DENTAL FLUOROSIS -- RISK FACTORS IN DENTAL FLUOROSIS -- THE RELATION BETWEEN DENTAL FLUOROSIS AND CARIES -- CONCLUSIONS -- RESEARCH RECOMMENDATIONS -- 3 Fluoride Exposure and Risk of Bone Fracture -- BONE FRACTURE IN HUMANS -- Clinical Trials of Fluoride -- Population Studies -- Studies Using Information from Individuals -- Studies Using Population Characteristics -- Skeletal Fluorosis -- Discussion -- BONE FRACTURE IN ANIMALS -- Discussion -- 4 Reproductive Effects of Fluoride -- REPRODUCTIVE EFFECTS IN HUMANS -- REPRODUCTIVE EFFECTS IN ANIMALS -- DISCUSSION -- 5 Effects of Ingested Fluoride on Renal, Gastrointestinal, and Immune Systems -- EFFECTS ON THE RENAL SYSTEM -- EFFECTS ON THE GASTROINTESTINAL SYSTEM -- HYPERSENSITIVITY AND IMMUNOLOGICAL EFFECTS -- DISCUSSION -- 6 Genotoxicity of Fluoride -- IN VITRO GENOTOXICITY TEST SYSTEMS -- Microbes -- Mammalian Cells -- Gene Mutations -- Chromosomal Aberrations and Sister Chromatid Exchanges -- Animal Cells -- Human Cells -- DNA Damage and Repair -- Transformation -- Discussion.
IN VIVO GENOTOXICITY TEST SYSTEMS -- Drosophila -- Rodents -- Somatic Cells -- Germ Cells -- Human Studies -- PROPOSED MECHANISMS OF GENOTOXICITY -- SUMMARY -- 7 Carcinogenicity of Fluoride -- FLUORIDE CARCINOGENCITY IN HUMANS -- FLUORIDE CARCINOGENICITY IN ANIMALS -- Early Toxicological Studies Of Fluoride and Cancer -- Recent Carcinogenicity Bioassays -- CONCLUSIONS -- RECOMMENDATIONS -- 8 Intake, Metabolism, and Disposition of Fluoride -- FLUORIDE INTAKE -- FLUORIDE ABSORPTION -- FLUORIDE IN PLASMA -- TISSUE DISTRIBUTION -- FLUORIDE EXCRETION -- RECOMMENDATIONS -- References -- Appendix 1 Criteria for Dean's Index, TF Index, and TSIF -- Appendix 2 Letter to AFIP -- Appendix 3 AFIP Response. |
| Record Nr. | UNINA-9910970035703321 |
| Washington, D.C., : National Academy Press, 1993 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||