Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 2004 |
Descrizione fisica | 1 online resource (309 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico |
Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects Hazardous substances - Health aspects Chemicals - Physiological effect Chemicals - Health aspects |
ISBN |
0-309-16655-1
1-280-17640-7 9786610176403 0-309-53013-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Front Matter -- Preface -- Contents -- Introduction -- Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances -- Appendixes -- 1 Chlorine: Acute Exposure Guideline Levels -- 2 Hydrogen Chloride: Acute Exposure Guideline Levels -- 3 Hydrogen Fluoride: Acute Exposure Guideline Levels -- 4 Toluene 2,4- and 2,6- Diisocyanate: Acute Exposure Guideline Levels -- 5 Uranium Hexafluoride: Acute Exposure Guideline Levels. |
Record Nr. | UNINA-9910829052803321 |
Washington, D.C., : National Academy Press, 2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2003 |
Descrizione fisica | 1 online resource (515 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico |
Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects Hazardous substances - Health aspects Chemicals - Physiological effect Chemicals - Health aspects |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-17995-3
9786610179954 0-309-53946-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910456233703321 |
Washington, D.C., : National Academy Press, c2003 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2003 |
Descrizione fisica | 1 online resource (515 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico |
Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects Hazardous substances - Health aspects Chemicals - Physiological effect Chemicals - Health aspects |
ISBN |
0-309-16816-3
1-280-17995-3 9786610179954 0-309-53946-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910780274503321 |
Washington, D.C., : National Academy Press, c2003 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2003 |
Descrizione fisica | 1 online resource (515 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico |
Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects Hazardous substances - Health aspects Chemicals - Physiological effect Chemicals - Health aspects |
ISBN |
0-309-16816-3
1-280-17995-3 9786610179954 0-309-53946-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Acute Exposure Guideline Levels for Selected Airborne Chemicals -- Copyright -- OTHER REPORTS OF THE BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY -- Preface -- Dedication -- Contents -- Introduction -- SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS -- REVIEW OF AEGL REPORTS -- REFERENCES -- Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances -- Appendixes -- 1 Nerve Agents GA, GB, GD, GF, and VX -- SUMMARY -- Derivation of G-Agent AEGL Estimates -- AEGL-1 and AEGL-2 Values for G-series Agents -- AEGL-3 Values for G-Series Agents -- Derivation of Agent VX AEGL Estimates -- Research Needs -- G-Series Agents -- Agent VX -- 1. INTRODUCTION -- 2. HUMAN TOXICITY DATA -- 2.1. Acute Lethality -- G Agents -- Agent VX -- 2.1.1. Case Reports -- Agent GB -- 2.2. Nonlethal Toxicity -- 2.2.1. Case Reports -- Agent GB -- 2.2.2. Acute Studies -- Agent GB -- Agent GD -- Agent GA -- Agent VX -- 2.2.3. Epidemiologic Studies -- 2.3. Neurotoxicity -- 2.4. Developmental and Reproductive Toxicity -- 2.5. Genotoxicity -- 2.6. Carcinogenicity -- 2.7. Summary -- G-series Agents -- Agent VX -- 3. ANIMAL TOXICITY DATA -- 3.1. Acute Lethality -- 3.1.1. Nonhuman Primates -- Agent GB -- Agent GA -- Agent GD -- 3.1.2. Dogs -- Agent GB -- Agent GA -- Agent VX -- 3.1.3. Rats -- Agent GB -- Agent GA -- Agent GD -- Agent GF -- Agent VX -- 3.1.4. Mice -- Agent GB -- Agent GD -- Agent GF -- Agent VX -- 3.1.5. Guinea pigs -- Agent GB -- Agent GD -- Agent VX -- 3.1.6. Rabbits -- Agent GB -- Agent GA -- Agent VX -- 3.1.7. Cats -- 3.1.8. Goats -- Agent VX -- 3.1.9. Hamsters -- Agent VX -- 3.1.10. Summary of Acute Lethality Data in Animals -- 3.2. Nonlethal Toxicity -- 3.2.1. Nonhuman Primates -- Agent GB -- Agent GD -- 3.2.2. Dogs -- Agent GB -- 3.2.3. Rats -- Agent GB -- Agent GD -- Agent GF -- Agent VX -- 3.2.4. Mice -- Agent GB.
Agent VX -- 3.2.5. Guinea pigs -- Agent GB -- Agent GD -- Agent VX -- 3.2.6. Rabbits -- Agent VX -- 3.2.7. Summary of Nonlethal Toxicity in Animals -- 3.3. Neurotoxicity -- 3.4. Developmental and Reproductive Effects -- 3.4.1. Rats -- Agent GB -- Agent GA -- Agent GD -- Agent VX -- 3.4.2. Guinea Pigs -- 3.4.3. Rabbits -- Agent GB -- Agent GA -- Agent GD -- Agent VX -- 3.4.4. Sheep -- Agent VX -- 3.4.5. Summary -- 3.5. Genotoxicity -- Agent GB -- Agent GA -- Agent VX -- Summary -- 3.6. Carcinogenicity -- Agent GB -- Agent GA -- Agent VX -- Summary -- 3.7. Summary -- G Agents -- Agent VX -- 4. SPECIAL CONSIDERATIONS -- 4.1. Metabolism, Toxicokinetics, and Disposition -- 4.1.1. Absorption -- 4.1.2. Toxicokinetics -- 4.1.3. Disposition and Metabolism -- 4.1.4. Distribution and Excretion -- 4.2. Mechanism of Toxicity -- 4.3. Relative Toxic Potency -- 4.3.1. In Vitro Potency -- 4.3.2. In Vivo Potency -- G Agents -- Agent VX -- Human Estimates ofGB and VX Toxicity -- 4.3.3. Comparison of Exposure Standards -- G-Series Agents -- Agent VX -- 4.3.4. Selection of Nerve Agent Potency Values for Use in Deriving AEGLs -- G Agents -- Agent VX -- 4.4. Structure-Activity Relationships -- 4.5. Other Relevant Information -- 4.5.1. Breathing Rates and Toxicity -- 4.5.2. Delayed Neuropathy -- G Agents -- Agent VX -- 4.5.3. Intra- and Interspecies Variability in Esterase Activity and Response to Nerve Agents -- Intraspecies Variability -- Interspecies Variability -- G-series Agents -- Agent VX -- 4.5.4. Unique Physicochemical Properties -- 4.5.5. Concurrent Exposure Issues -- Multiple Exposures to Similar Chemicals -- Multiple Exposure Through Different Exposure Pathways -- 4.5.6. Critical Effect End Point -- 5. DATA ANALYSIS FOR AEGL-1 -- 5.1. Summary of Human Data Relevant to AEGL-1 -- G-Series Agents -- Agent VX -- 5.2. Summary of Animal Data Relevant to AEGL-1. G-Series Agents -- Agent VX -- 5.3. Derivation of AEGL-1 for Agent GB -- Derivation of AEGL-1 Values Using Animal Data -- 5.4. Derivation of AEGL-1 Values for Agents GA, GD, and GF -- 5.5. Derivation of AEGL-1 for Agent VX -- 6. DATA ANALYSIS FOR AEGL-2 -- 6.1. Summary of Human Data Relevant to AEGL-2 -- 6.2. Summary of Animal Data Relevant to AEGL-2 -- 6.3. Derivation of AEGL-2 for Agent GB -- 6.4. Derivation of AEGL-2 Values for Agents GA, GD, and GF -- 6.5. Derivation of AEGL-2 Values for Agent VX -- 7. DATA ANALYSIS FOR AEGL-3 -- 7.1. Summary of Human Data Relevant to AEGL-3 -- 7.2. Summary of Animal Data Relevant to AEGL-3 -- Agent GB -- Agent GD -- Agent GF -- 7.3. Derivation of AEGL-3 for Agents GB and GD -- Agent GB -- Benchmark Exposure Analyses -- Agent GD -- 7.4. Derivation of AEGL-3 Values for Agents GA and GF -- 7.5. Derivation of AEGL-3 Values for Agent VX -- 8. SUMMARY OF AEGLS -- 8.1. AEGL Values and Toxicity End Points -- G-Series Agents -- Agent VX -- 8.2. Comparison with other Standards and Criteria -- G Agents -- Agent VX -- 8.3. Data Adequacy and Research Needs -- G Agents -- Agent VX -- 9. REFERENCES -- Appendixes -- APPENDIX A DERIVATION OF AEGL VALUES -- Derivation of AEGL-1 -- Derivation of AEGL-1 for Agent GB (Sarin) from Human Data Set -- Derivation of AEGL-2 for Agent GB (Sarin) -- Derivation of AEGL-3 for Agent GB (Sarin) -- Derivation of AEGL-3 for Agent GD (Alternate Estimate) -- Derivation of AEGL-1 for Agent VX Vapor from Agent GB Toxicity Data -- Derivation of AEGL-2 for Agent VX Vapor from Agent GB Toxicity Data -- Derivation of AEGL-3 for Agent VX Vapor from Agent GB Toxicity Data -- APPENDIX B Concentration-Time Curve for Sarin-Induced Miosis in Humans and Lethality in SD Rats -- APPENDIX C Benchmark Exposure Analysis of GB Vapor Lethality Data for Female SD Rats. APPENDIX D DERIVATION SUMMARY FOR ACUTE EXPOSURE GUIDELINE LEVELS FOR NERVE AGENTS -- Derivation Summary For Agent GA (CAS No. 77-81-6) (Tabun -- Dimethylamidocyanophosphate) -- Derivation Summary for Agent GB (CAS No. 107-44-8) (Sarin -- Isopropylmethylphosphonofluoridate) -- Derivation Summary for Agent GD (CAS No. 96-64-0) (Soman -- Pinacolyl Methylphosphonofluoridate) -- Derivation Summary for Agent GF (CAS No. 329-99-7) (O-cyclohexyl-methlyfluorophosphonate) -- Derivation Summary for Agent VX Vapor (CAS No. 50782-69-9) (O-Ethyl-S-(Isopropyl-Aminoethyl)Methyl P ... -- 2 Sulfur Mustard (Agent HD) -- SUMMARY -- I. INTRODUCTION -- 2. HUMAN TOXICITY DATA -- 2.1. Acute Lethality -- 2.2. Nonlethal Toxicity -- 2.2.1. Epidemiologic Studies -- 2.3. Neurotoxicity -- 2.4. Developmental and Reproductive Toxicity -- 2.5. Genotoxicity -- 2.6. Carcinogenicity -- 2.7. Summary -- 3. ANIMAL TOXICITY DATA -- 3.1. Acute Lethality -- 3.1.1. Rats -- 3.1.2 Mice -- 3.1.3. Guinea pigs -- 3.2. Nonlethal Toxicity -- 3.2.1. Dogs -- 3.2.2. Rats -- 3.2.3. Mice -- 3.2.4. Rabbits -- 3.2.5. Guinea pigs -- 3.3. Neurotoxicity -- 3.4. Developmental and Reproductive Toxicity -- 3.5. Genotoxicity -- 3.6. Chronic Toxicity and Carcinogenicity -- 3.7. Summary -- 4. SPECIAL CONSIDERATIONS -- 4.1. Metabolism and Disposition -- 4.2. Mechanism of Toxicity -- 4.3. Structure-Activity Relationships -- 4.4. Other Relevant Information -- 4.4.1. Species Variability -- 5. DATA ANALYSIS FOR AEGL-1 -- 5.1. Summary of Human Data Relevant to AEGL-1 -- 5.2. SUMMARY OF ANIMAL DATA RELEVANT TO AEGL-1 -- 5.3. Derivation of AEGL-1 -- 6. DATA ANALYSIS FOR AEGL-2 -- 6.1. Summary of Human Data Relevant to AEGL-2 -- 6.2. Summary of Animal Data Relevant to AEGL-2 -- 6.3. Derivation of AEGL-2 -- 7. DATA ANALYSIS FOR AEGL-3 -- 7.1. Summary of Human Data Relevant to AEGL-3. 7.2. Summary of Animal Data Relevant to AEGL-3 -- 7.3. Derivation of AEGL-3 -- 8. SUMMARY OF AEGLS -- 8.1. AEGL Values and Toxicity End Points -- 8.2. Comparison with Other Standards and Guidelines -- 8.3. Data Adequacy and Research Needs -- 9. REFERENCES -- Appendixes -- APPENDIX A Derivations of AEGL Values -- Derivation of AEGL-1 -- Derivation of AEGL-2 -- Derivation of AEGL-3 -- APPENDIX B Determination of Temporal Scaling Factor (n) for AEGL Derivations -- APPENDIX C Carcinogenicity Assessment for Acute Exposure to Sulfur Mustard (Agent HD) -- APPENDIX D -- Sulfur Mustard (CAS NO. 505-60-2) -- 3 Methyl Isocyanate -- SUMMARY -- 1. INTRODUCTION -- 2. HUMAN TOXICITY DATA -- 2.1. Bhopal Disaster -- 2.2. Nonlethal Toxicity -- 2.2.1. Case Reports -- 2.2.2. Experimental Studies -- 2.3. Developmental and Reproductive Toxicity -- 2.4. Genotoxicity -- 2.5. Carcinogenicity -- 2.6. Summary -- 3. ANIMAL TOXICITY DATA -- 3.1. Acute Lethality -- 3.1.1. Rabbits -- 3.1.2. Guinea Pigs -- 3.1.3. Rats -- 3.1.4. Mice -- 3.2. Nonlethal Toxicity -- 3.2.1. Guinea Pigs -- 3.2.2. Rats -- 3.2.3. Mice -- 3.3. Developmental and Reproductive Toxicity -- 3.4. Genotoxicity -- 3.5. Chronic Toxicity and Carcinogenicity -- 3.6. Summary -- 4. SPECIAL CONSIDERATIONS -- 4.1. Metabolism and Disposition -- 4.2. Mechanism of Toxicity -- 4.3. Other Relevant Information -- 4.3.1. Species Variability -- 4.3.2. Concentration-Exposure Duration Relationship -- 5. DATA ANALYSIS FOR AEGL-1 -- 5.1. Summary of Human Data Relevant to AEGL-1 -- 5.2. Summary of Animal Data Relevant to AEGL-1 -- 5.3. Derivation of AEGL-1 -- 6. DATA ANALYSIS FOR AEGL-2 -- 6.1. Summary of Human Data Relevant to AEGL-2 -- 6.2. Summary of Animal Data Relevant to AEGL-2 -- 6.3. Derivation of AEGL-2 -- 7. DATA ANALYSIS FOR AEGL-3 -- 7.1. Summary of Human Data Relevant to AEGL-3. 7.2. Summary of Animal Data Relevant to AEGL-3. |
Record Nr. | UNINA-9910826235603321 |
Washington, D.C., : National Academy Press, c2003 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2000 |
Descrizione fisica | 1 online resource (219 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico |
Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects Hazardous substances - Health aspects Chemicals - Physiological effect Chemicals - Health aspects |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-18513-9
9786610185139 0-309-56508-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""
""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity"" ""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2"" ""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports"" ""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS"" ""4.1. Metabolism and Disposition"" |
Record Nr. | UNINA-9910456028003321 |
Washington, D.C., : National Academy Press, c2000 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2000 |
Descrizione fisica | 1 online resource (219 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico |
Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects Hazardous substances - Health aspects Chemicals - Physiological effect Chemicals - Health aspects |
ISBN |
0-309-18354-5
1-280-18513-9 9786610185139 0-309-56508-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""
""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity"" ""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2"" ""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports"" ""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS"" ""4.1. Metabolism and Disposition"" |
Record Nr. | UNINA-9910778610303321 |
Washington, D.C., : National Academy Press, c2000 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2000 |
Descrizione fisica | 1 online resource (219 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico |
Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects Hazardous substances - Health aspects Chemicals - Physiological effect Chemicals - Health aspects |
ISBN |
0-309-18354-5
1-280-18513-9 9786610185139 0-309-56508-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""
""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity"" ""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2"" ""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports"" ""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS"" ""4.1. Metabolism and Disposition"" |
Record Nr. | UNINA-9910826477003321 |
Washington, D.C., : National Academy Press, c2000 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council |
Edizione | [1st ed.] |
Pubbl/distr/stampa |
Washington, D.C., : National Academy Press, c2000- |
Descrizione fisica | 1 online resource (292 p.) |
Disciplina | 615.9/1 |
Collana | The compass series |
Soggetto topico | Gases, Asphyxiating and poisonous |
ISBN |
0-309-17890-8
1-280-84424-8 9786610844241 0-309-66687-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Front Matter""; ""Preface""; ""Contents""; ""Introduction""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""Appendixes""; ""1 Chlorine Dioxide Acute Exposure Guideline Levels (AEGLs)""; ""2 Chlorine Trifluoride Acute Exposure Guideline Levels""; ""3 Cyclohexylamine Acute Exposure Guideline Levels""; ""4 Ethylenediamine Acute Exposure Guideline Levels""; ""5 HFE-7100: Methyl Nonafluorobutyl Ether (40%) (CAS Reg. No. 163702-07-6) plus Methyl Nonafluoroisobutyl Ether (60%) (CAS Reg. No. 163702-08-7) Acute Exposure Guideline Levels""
""6 Tetranitromethane Acute Exposure Guideline Levels"" |
Record Nr. | UNINA-9910824888903321 |
Washington, D.C., : National Academy Press, c2000- <c2007> | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Characterization and toxicity of smoke |
Pubbl/distr/stampa | [Place of publication not identified], : ASTM, 1990 |
Disciplina | 615.9/1 |
Collana | STP Characterization and toxicity of smoke |
Soggetto topico |
Combustion gases - Congresses - Toxicology
Smoke - Toxicology - Congresses Particulate Matter Pharmacology Inorganic Chemicals Environment Health Occupations Biological Science Disciplines Environment and Public Health Complex Mixtures Health Care Natural Science Disciplines Occupations Toxicology Gases Fires Smoke Public Health Health & Biological Sciences Toxicology & Public Health |
ISBN | 0-8031-5140-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910164308803321 |
[Place of publication not identified], : ASTM, 1990 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Inhalation toxicology of air pollution : clinical research considerations / / Robert Frank [et al.], editors |
Pubbl/distr/stampa | Philadelphia : , : ASTM, , 1985 |
Descrizione fisica | 1 online resource (157 pages) : illustrations |
Disciplina | 615.9/1 |
Collana | ASTM special technical publication Inhalation toxicology of air pollution |
Soggetto topico |
Air - Pollution - Toxicology
Lungs - Diseases - Research Air - Pollution - Physiological effect - Measurement |
ISBN | 0-8031-4937-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Inhalation Toxicology of Air Pollution |
Record Nr. | UNINA-9910164708603321 |
Philadelphia : , : ASTM, , 1985 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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