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Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Edizione [1st ed.]
Pubbl/distr/stampa Washington, D.C., : National Academy Press, 2004
Descrizione fisica 1 online resource (309 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects
Hazardous substances - Health aspects
Chemicals - Physiological effect
Chemicals - Health aspects
ISBN 0-309-16655-1
1-280-17640-7
9786610176403
0-309-53013-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Matter -- Preface -- Contents -- Introduction -- Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances -- Appendixes -- 1 Chlorine: Acute Exposure Guideline Levels -- 2 Hydrogen Chloride: Acute Exposure Guideline Levels -- 3 Hydrogen Fluoride: Acute Exposure Guideline Levels -- 4 Toluene 2,4- and 2,6- Diisocyanate: Acute Exposure Guideline Levels -- 5 Uranium Hexafluoride: Acute Exposure Guideline Levels.
Record Nr. UNINA-9910829052803321
Washington, D.C., : National Academy Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Pubbl/distr/stampa Washington, D.C., : National Academy Press, c2003
Descrizione fisica 1 online resource (515 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects
Hazardous substances - Health aspects
Chemicals - Physiological effect
Chemicals - Health aspects
Soggetto genere / forma Electronic books.
ISBN 1-280-17995-3
9786610179954
0-309-53946-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910456233703321
Washington, D.C., : National Academy Press, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Pubbl/distr/stampa Washington, D.C., : National Academy Press, c2003
Descrizione fisica 1 online resource (515 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects
Hazardous substances - Health aspects
Chemicals - Physiological effect
Chemicals - Health aspects
ISBN 0-309-16816-3
1-280-17995-3
9786610179954
0-309-53946-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910780274503321
Washington, D.C., : National Academy Press, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Edizione [1st ed.]
Pubbl/distr/stampa Washington, D.C., : National Academy Press, c2003
Descrizione fisica 1 online resource (515 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects
Hazardous substances - Health aspects
Chemicals - Physiological effect
Chemicals - Health aspects
ISBN 0-309-16816-3
1-280-17995-3
9786610179954
0-309-53946-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Acute Exposure Guideline Levels for Selected Airborne Chemicals -- Copyright -- OTHER REPORTS OF THE BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY -- Preface -- Dedication -- Contents -- Introduction -- SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS -- REVIEW OF AEGL REPORTS -- REFERENCES -- Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances -- Appendixes -- 1 Nerve Agents GA, GB, GD, GF, and VX -- SUMMARY -- Derivation of G-Agent AEGL Estimates -- AEGL-1 and AEGL-2 Values for G-series Agents -- AEGL-3 Values for G-Series Agents -- Derivation of Agent VX AEGL Estimates -- Research Needs -- G-Series Agents -- Agent VX -- 1. INTRODUCTION -- 2. HUMAN TOXICITY DATA -- 2.1. Acute Lethality -- G Agents -- Agent VX -- 2.1.1. Case Reports -- Agent GB -- 2.2. Nonlethal Toxicity -- 2.2.1. Case Reports -- Agent GB -- 2.2.2. Acute Studies -- Agent GB -- Agent GD -- Agent GA -- Agent VX -- 2.2.3. Epidemiologic Studies -- 2.3. Neurotoxicity -- 2.4. Developmental and Reproductive Toxicity -- 2.5. Genotoxicity -- 2.6. Carcinogenicity -- 2.7. Summary -- G-series Agents -- Agent VX -- 3. ANIMAL TOXICITY DATA -- 3.1. Acute Lethality -- 3.1.1. Nonhuman Primates -- Agent GB -- Agent GA -- Agent GD -- 3.1.2. Dogs -- Agent GB -- Agent GA -- Agent VX -- 3.1.3. Rats -- Agent GB -- Agent GA -- Agent GD -- Agent GF -- Agent VX -- 3.1.4. Mice -- Agent GB -- Agent GD -- Agent GF -- Agent VX -- 3.1.5. Guinea pigs -- Agent GB -- Agent GD -- Agent VX -- 3.1.6. Rabbits -- Agent GB -- Agent GA -- Agent VX -- 3.1.7. Cats -- 3.1.8. Goats -- Agent VX -- 3.1.9. Hamsters -- Agent VX -- 3.1.10. Summary of Acute Lethality Data in Animals -- 3.2. Nonlethal Toxicity -- 3.2.1. Nonhuman Primates -- Agent GB -- Agent GD -- 3.2.2. Dogs -- Agent GB -- 3.2.3. Rats -- Agent GB -- Agent GD -- Agent GF -- Agent VX -- 3.2.4. Mice -- Agent GB.
Agent VX -- 3.2.5. Guinea pigs -- Agent GB -- Agent GD -- Agent VX -- 3.2.6. Rabbits -- Agent VX -- 3.2.7. Summary of Nonlethal Toxicity in Animals -- 3.3. Neurotoxicity -- 3.4. Developmental and Reproductive Effects -- 3.4.1. Rats -- Agent GB -- Agent GA -- Agent GD -- Agent VX -- 3.4.2. Guinea Pigs -- 3.4.3. Rabbits -- Agent GB -- Agent GA -- Agent GD -- Agent VX -- 3.4.4. Sheep -- Agent VX -- 3.4.5. Summary -- 3.5. Genotoxicity -- Agent GB -- Agent GA -- Agent VX -- Summary -- 3.6. Carcinogenicity -- Agent GB -- Agent GA -- Agent VX -- Summary -- 3.7. Summary -- G Agents -- Agent VX -- 4. SPECIAL CONSIDERATIONS -- 4.1. Metabolism, Toxicokinetics, and Disposition -- 4.1.1. Absorption -- 4.1.2. Toxicokinetics -- 4.1.3. Disposition and Metabolism -- 4.1.4. Distribution and Excretion -- 4.2. Mechanism of Toxicity -- 4.3. Relative Toxic Potency -- 4.3.1. In Vitro Potency -- 4.3.2. In Vivo Potency -- G Agents -- Agent VX -- Human Estimates ofGB and VX Toxicity -- 4.3.3. Comparison of Exposure Standards -- G-Series Agents -- Agent VX -- 4.3.4. Selection of Nerve Agent Potency Values for Use in Deriving AEGLs -- G Agents -- Agent VX -- 4.4. Structure-Activity Relationships -- 4.5. Other Relevant Information -- 4.5.1. Breathing Rates and Toxicity -- 4.5.2. Delayed Neuropathy -- G Agents -- Agent VX -- 4.5.3. Intra- and Interspecies Variability in Esterase Activity and Response to Nerve Agents -- Intraspecies Variability -- Interspecies Variability -- G-series Agents -- Agent VX -- 4.5.4. Unique Physicochemical Properties -- 4.5.5. Concurrent Exposure Issues -- Multiple Exposures to Similar Chemicals -- Multiple Exposure Through Different Exposure Pathways -- 4.5.6. Critical Effect End Point -- 5. DATA ANALYSIS FOR AEGL-1 -- 5.1. Summary of Human Data Relevant to AEGL-1 -- G-Series Agents -- Agent VX -- 5.2. Summary of Animal Data Relevant to AEGL-1.
G-Series Agents -- Agent VX -- 5.3. Derivation of AEGL-1 for Agent GB -- Derivation of AEGL-1 Values Using Animal Data -- 5.4. Derivation of AEGL-1 Values for Agents GA, GD, and GF -- 5.5. Derivation of AEGL-1 for Agent VX -- 6. DATA ANALYSIS FOR AEGL-2 -- 6.1. Summary of Human Data Relevant to AEGL-2 -- 6.2. Summary of Animal Data Relevant to AEGL-2 -- 6.3. Derivation of AEGL-2 for Agent GB -- 6.4. Derivation of AEGL-2 Values for Agents GA, GD, and GF -- 6.5. Derivation of AEGL-2 Values for Agent VX -- 7. DATA ANALYSIS FOR AEGL-3 -- 7.1. Summary of Human Data Relevant to AEGL-3 -- 7.2. Summary of Animal Data Relevant to AEGL-3 -- Agent GB -- Agent GD -- Agent GF -- 7.3. Derivation of AEGL-3 for Agents GB and GD -- Agent GB -- Benchmark Exposure Analyses -- Agent GD -- 7.4. Derivation of AEGL-3 Values for Agents GA and GF -- 7.5. Derivation of AEGL-3 Values for Agent VX -- 8. SUMMARY OF AEGLS -- 8.1. AEGL Values and Toxicity End Points -- G-Series Agents -- Agent VX -- 8.2. Comparison with other Standards and Criteria -- G Agents -- Agent VX -- 8.3. Data Adequacy and Research Needs -- G Agents -- Agent VX -- 9. REFERENCES -- Appendixes -- APPENDIX A DERIVATION OF AEGL VALUES -- Derivation of AEGL-1 -- Derivation of AEGL-1 for Agent GB (Sarin) from Human Data Set -- Derivation of AEGL-2 for Agent GB (Sarin) -- Derivation of AEGL-3 for Agent GB (Sarin) -- Derivation of AEGL-3 for Agent GD (Alternate Estimate) -- Derivation of AEGL-1 for Agent VX Vapor from Agent GB Toxicity Data -- Derivation of AEGL-2 for Agent VX Vapor from Agent GB Toxicity Data -- Derivation of AEGL-3 for Agent VX Vapor from Agent GB Toxicity Data -- APPENDIX B Concentration-Time Curve for Sarin-Induced Miosis in Humans and Lethality in SD Rats -- APPENDIX C Benchmark Exposure Analysis of GB Vapor Lethality Data for Female SD Rats.
APPENDIX D DERIVATION SUMMARY FOR ACUTE EXPOSURE GUIDELINE LEVELS FOR NERVE AGENTS -- Derivation Summary For Agent GA (CAS No. 77-81-6) (Tabun -- Dimethylamidocyanophosphate) -- Derivation Summary for Agent GB (CAS No. 107-44-8) (Sarin -- Isopropylmethylphosphonofluoridate) -- Derivation Summary for Agent GD (CAS No. 96-64-0) (Soman -- Pinacolyl Methylphosphonofluoridate) -- Derivation Summary for Agent GF (CAS No. 329-99-7) (O-cyclohexyl-methlyfluorophosphonate) -- Derivation Summary for Agent VX Vapor (CAS No. 50782-69-9) (O-Ethyl-S-(Isopropyl-Aminoethyl)Methyl P ... -- 2 Sulfur Mustard (Agent HD) -- SUMMARY -- I. INTRODUCTION -- 2. HUMAN TOXICITY DATA -- 2.1. Acute Lethality -- 2.2. Nonlethal Toxicity -- 2.2.1. Epidemiologic Studies -- 2.3. Neurotoxicity -- 2.4. Developmental and Reproductive Toxicity -- 2.5. Genotoxicity -- 2.6. Carcinogenicity -- 2.7. Summary -- 3. ANIMAL TOXICITY DATA -- 3.1. Acute Lethality -- 3.1.1. Rats -- 3.1.2 Mice -- 3.1.3. Guinea pigs -- 3.2. Nonlethal Toxicity -- 3.2.1. Dogs -- 3.2.2. Rats -- 3.2.3. Mice -- 3.2.4. Rabbits -- 3.2.5. Guinea pigs -- 3.3. Neurotoxicity -- 3.4. Developmental and Reproductive Toxicity -- 3.5. Genotoxicity -- 3.6. Chronic Toxicity and Carcinogenicity -- 3.7. Summary -- 4. SPECIAL CONSIDERATIONS -- 4.1. Metabolism and Disposition -- 4.2. Mechanism of Toxicity -- 4.3. Structure-Activity Relationships -- 4.4. Other Relevant Information -- 4.4.1. Species Variability -- 5. DATA ANALYSIS FOR AEGL-1 -- 5.1. Summary of Human Data Relevant to AEGL-1 -- 5.2. SUMMARY OF ANIMAL DATA RELEVANT TO AEGL-1 -- 5.3. Derivation of AEGL-1 -- 6. DATA ANALYSIS FOR AEGL-2 -- 6.1. Summary of Human Data Relevant to AEGL-2 -- 6.2. Summary of Animal Data Relevant to AEGL-2 -- 6.3. Derivation of AEGL-2 -- 7. DATA ANALYSIS FOR AEGL-3 -- 7.1. Summary of Human Data Relevant to AEGL-3.
7.2. Summary of Animal Data Relevant to AEGL-3 -- 7.3. Derivation of AEGL-3 -- 8. SUMMARY OF AEGLS -- 8.1. AEGL Values and Toxicity End Points -- 8.2. Comparison with Other Standards and Guidelines -- 8.3. Data Adequacy and Research Needs -- 9. REFERENCES -- Appendixes -- APPENDIX A Derivations of AEGL Values -- Derivation of AEGL-1 -- Derivation of AEGL-2 -- Derivation of AEGL-3 -- APPENDIX B Determination of Temporal Scaling Factor (n) for AEGL Derivations -- APPENDIX C Carcinogenicity Assessment for Acute Exposure to Sulfur Mustard (Agent HD) -- APPENDIX D -- Sulfur Mustard (CAS NO. 505-60-2) -- 3 Methyl Isocyanate -- SUMMARY -- 1. INTRODUCTION -- 2. HUMAN TOXICITY DATA -- 2.1. Bhopal Disaster -- 2.2. Nonlethal Toxicity -- 2.2.1. Case Reports -- 2.2.2. Experimental Studies -- 2.3. Developmental and Reproductive Toxicity -- 2.4. Genotoxicity -- 2.5. Carcinogenicity -- 2.6. Summary -- 3. ANIMAL TOXICITY DATA -- 3.1. Acute Lethality -- 3.1.1. Rabbits -- 3.1.2. Guinea Pigs -- 3.1.3. Rats -- 3.1.4. Mice -- 3.2. Nonlethal Toxicity -- 3.2.1. Guinea Pigs -- 3.2.2. Rats -- 3.2.3. Mice -- 3.3. Developmental and Reproductive Toxicity -- 3.4. Genotoxicity -- 3.5. Chronic Toxicity and Carcinogenicity -- 3.6. Summary -- 4. SPECIAL CONSIDERATIONS -- 4.1. Metabolism and Disposition -- 4.2. Mechanism of Toxicity -- 4.3. Other Relevant Information -- 4.3.1. Species Variability -- 4.3.2. Concentration-Exposure Duration Relationship -- 5. DATA ANALYSIS FOR AEGL-1 -- 5.1. Summary of Human Data Relevant to AEGL-1 -- 5.2. Summary of Animal Data Relevant to AEGL-1 -- 5.3. Derivation of AEGL-1 -- 6. DATA ANALYSIS FOR AEGL-2 -- 6.1. Summary of Human Data Relevant to AEGL-2 -- 6.2. Summary of Animal Data Relevant to AEGL-2 -- 6.3. Derivation of AEGL-2 -- 7. DATA ANALYSIS FOR AEGL-3 -- 7.1. Summary of Human Data Relevant to AEGL-3.
7.2. Summary of Animal Data Relevant to AEGL-3.
Record Nr. UNINA-9910826235603321
Washington, D.C., : National Academy Press, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Pubbl/distr/stampa Washington, D.C., : National Academy Press, c2000
Descrizione fisica 1 online resource (219 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects
Hazardous substances - Health aspects
Chemicals - Physiological effect
Chemicals - Health aspects
Soggetto genere / forma Electronic books.
ISBN 1-280-18513-9
9786610185139
0-309-56508-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""
""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""
""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2""
""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports""
""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS""
""4.1. Metabolism and Disposition""
Record Nr. UNINA-9910456028003321
Washington, D.C., : National Academy Press, c2000
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Pubbl/distr/stampa Washington, D.C., : National Academy Press, c2000
Descrizione fisica 1 online resource (219 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects
Hazardous substances - Health aspects
Chemicals - Physiological effect
Chemicals - Health aspects
ISBN 0-309-18354-5
1-280-18513-9
9786610185139
0-309-56508-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""
""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""
""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2""
""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports""
""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS""
""4.1. Metabolism and Disposition""
Record Nr. UNINA-9910778610303321
Washington, D.C., : National Academy Press, c2000
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Edizione [1st ed.]
Pubbl/distr/stampa Washington, D.C., : National Academy Press, c2000
Descrizione fisica 1 online resource (219 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
Hazardous substances - Environmental aspects
Hazardous substances - Health aspects
Chemicals - Physiological effect
Chemicals - Health aspects
ISBN 0-309-18354-5
1-280-18513-9
9786610185139
0-309-56508-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""
""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""
""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2""
""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports""
""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS""
""4.1. Metabolism and Disposition""
Record Nr. UNINA-9910826477003321
Washington, D.C., : National Academy Press, c2000
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Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Acute exposure guideline levels for selected airborne chemicals / / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
Edizione [1st ed.]
Pubbl/distr/stampa Washington, D.C., : National Academy Press, c2000-
Descrizione fisica 1 online resource (292 p.)
Disciplina 615.9/1
Collana The compass series
Soggetto topico Gases, Asphyxiating and poisonous
ISBN 0-309-17890-8
1-280-84424-8
9786610844241
0-309-66687-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Front Matter""; ""Preface""; ""Contents""; ""Introduction""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""Appendixes""; ""1 Chlorine Dioxide Acute Exposure Guideline Levels (AEGLs)""; ""2 Chlorine Trifluoride Acute Exposure Guideline Levels""; ""3 Cyclohexylamine Acute Exposure Guideline Levels""; ""4 Ethylenediamine Acute Exposure Guideline Levels""; ""5 HFE-7100: Methyl Nonafluorobutyl Ether (40%) (CAS Reg. No. 163702-07-6) plus Methyl Nonafluoroisobutyl Ether (60%) (CAS Reg. No. 163702-08-7) Acute Exposure Guideline Levels""
""6 Tetranitromethane Acute Exposure Guideline Levels""
Record Nr. UNINA-9910824888903321
Washington, D.C., : National Academy Press, c2000- <c2007>
Materiale a stampa
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Characterization and toxicity of smoke
Characterization and toxicity of smoke
Pubbl/distr/stampa [Place of publication not identified], : ASTM, 1990
Disciplina 615.9/1
Collana STP Characterization and toxicity of smoke
Soggetto topico Combustion gases - Congresses - Toxicology
Smoke - Toxicology - Congresses
Particulate Matter
Pharmacology
Inorganic Chemicals
Environment
Health Occupations
Biological Science Disciplines
Environment and Public Health
Complex Mixtures
Health Care
Natural Science Disciplines
Occupations
Toxicology
Gases
Fires
Smoke
Public Health
Health & Biological Sciences
Toxicology & Public Health
ISBN 0-8031-5140-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910164308803321
[Place of publication not identified], : ASTM, 1990
Materiale a stampa
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Inhalation toxicology of air pollution : clinical research considerations / / Robert Frank [et al.], editors
Inhalation toxicology of air pollution : clinical research considerations / / Robert Frank [et al.], editors
Pubbl/distr/stampa Philadelphia : , : ASTM, , 1985
Descrizione fisica 1 online resource (157 pages) : illustrations
Disciplina 615.9/1
Collana ASTM special technical publication Inhalation toxicology of air pollution
Soggetto topico Air - Pollution - Toxicology
Lungs - Diseases - Research
Air - Pollution - Physiological effect - Measurement
ISBN 0-8031-4937-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Inhalation Toxicology of Air Pollution
Record Nr. UNINA-9910164708603321
Philadelphia : , : ASTM, , 1985
Materiale a stampa
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