Uncertainty modeling in dose response [[electronic resource] ] : bench testing environmental toxicity / / Roger M. Cooke |
Autore | Cooke Roger M. <1946-> |
Pubbl/distr/stampa | Hoboken, : Wiley, c2009 |
Descrizione fisica | 1 online resource (246 p.) |
Disciplina | 615.9/02011 |
Altri autori (Persone) | CookeRoger M. <1946-> |
Collana | Statistics in Practice |
Soggetto topico |
Environmental toxicology - Mathematical models
Toxicology - Dose-response relationship - Mathematical models |
ISBN |
1-282-69103-1
9786612691034 0-470-48140-4 0-470-48139-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
UNCERTAINTY MODELING IN DOSE RESPONSE; CONTENTS; Acknowledgments; Contributors; Introduction; 1 Analysis of Dose-Response Uncertainty Using Benchmark Dose Modeling; Comment: The Math/Stats Perspective on Chapter 1: Hard Problems Remain; Comment: EPI/TOX Perspective on Chapter 1: Re-formulating the Issues; Comment: Regulatory/Risk Perspective on Chapter 1: A Good Baseline; Comment: A Question Dangles; Comment: Statistical Test for Statistics-as-Usual Confidence Bands; Response to Comments
2 Uncertainty Quantification for Dose-Response Models Using Probabilistic Inversion with Isotonic Regression: Bench Test ResultsComment: Math/Stats Perspective on Chapter 2: Agreement and Disagreement; Comment: EPI/TOX Perspective on Chapter 2: What Data Sets Per se Say; Comment: Regulatory/Risk Perspective on Chapter 2: Substantial Advances Nourish Hope for Clarity?; Comment: A Weakness in the Approach?; Response to Comments; 3 Uncertainty Modeling in Dose Response Using Nonparametric Bayes: Bench Test Results; Comment: Math/Stats Perspective on Chapter 3: Nonparametric Bayes Comment: EPI/TOX View on Nonparametric Bayes: Dosing PrecisionComment: Regulator/Risk Perspective on Chapter 3: Failure to Communicate; Response to Comments; 4 Quantifying Dose-Response Uncertainty Using Bayesian Model Averaging; Comment: Math/Stats Perspective on Chapter 4: Bayesian Model Averaging; Comment: EPI/TOX Perspective on Chapter 4: Use of Bayesian Model Averaging for Addressing Uncertainties in Cancer Dose-Response Modeling; Comment: Regulatorary/Risk Perspective on Chapter 4: Model Averages, Model Amalgams, and Model Choice; Response to Comments 5 Combining Risks from Several Tumors Using Markov Chain Monte Carlo6 Uncertainty in Dose Response from the Perspective of Microbial Risk; 7 Conclusions; Author Index; Subject Index |
Record Nr. | UNINA-9910143128803321 |
Cooke Roger M. <1946-> | ||
Hoboken, : Wiley, c2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Uncertainty modeling in dose response : bench testing environmental toxicity / / Roger M. Cooke |
Autore | Cooke Roger M. <1946-> |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, : Wiley, c2009 |
Descrizione fisica | 1 online resource (246 p.) |
Disciplina | 615.9/02011 |
Collana | Statistics in Practice |
Soggetto topico |
Environmental toxicology - Mathematical models
Toxicology - Dose-response relationship - Mathematical models |
ISBN |
1-282-69103-1
9786612691034 0-470-48140-4 0-470-48139-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
UNCERTAINTY MODELING IN DOSE RESPONSE; CONTENTS; Acknowledgments; Contributors; Introduction; 1 Analysis of Dose-Response Uncertainty Using Benchmark Dose Modeling; Comment: The Math/Stats Perspective on Chapter 1: Hard Problems Remain; Comment: EPI/TOX Perspective on Chapter 1: Re-formulating the Issues; Comment: Regulatory/Risk Perspective on Chapter 1: A Good Baseline; Comment: A Question Dangles; Comment: Statistical Test for Statistics-as-Usual Confidence Bands; Response to Comments
2 Uncertainty Quantification for Dose-Response Models Using Probabilistic Inversion with Isotonic Regression: Bench Test ResultsComment: Math/Stats Perspective on Chapter 2: Agreement and Disagreement; Comment: EPI/TOX Perspective on Chapter 2: What Data Sets Per se Say; Comment: Regulatory/Risk Perspective on Chapter 2: Substantial Advances Nourish Hope for Clarity?; Comment: A Weakness in the Approach?; Response to Comments; 3 Uncertainty Modeling in Dose Response Using Nonparametric Bayes: Bench Test Results; Comment: Math/Stats Perspective on Chapter 3: Nonparametric Bayes Comment: EPI/TOX View on Nonparametric Bayes: Dosing PrecisionComment: Regulator/Risk Perspective on Chapter 3: Failure to Communicate; Response to Comments; 4 Quantifying Dose-Response Uncertainty Using Bayesian Model Averaging; Comment: Math/Stats Perspective on Chapter 4: Bayesian Model Averaging; Comment: EPI/TOX Perspective on Chapter 4: Use of Bayesian Model Averaging for Addressing Uncertainties in Cancer Dose-Response Modeling; Comment: Regulatorary/Risk Perspective on Chapter 4: Model Averages, Model Amalgams, and Model Choice; Response to Comments 5 Combining Risks from Several Tumors Using Markov Chain Monte Carlo6 Uncertainty in Dose Response from the Perspective of Microbial Risk; 7 Conclusions; Author Index; Subject Index |
Record Nr. | UNINA-9910809270703321 |
Cooke Roger M. <1946-> | ||
Hoboken, : Wiley, c2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|