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3. : I recettori adrenergici / Mario Giannella, Wilma Quaglia
3. : I recettori adrenergici / Mario Giannella, Wilma Quaglia
Autore GIANNELLA, Mario
Pubbl/distr/stampa Bologna : CLUEB, stampa 1998
Descrizione fisica XII, 158 p. ; 24 cm
Disciplina 615.78
Altri autori (Persone) QUAGLIA, Wilma
Collana Manuali & antologie
Soggetto topico Recettori adrenergici - Chimica farmaceutica
ISBN 88-491-1137-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione ita
Record Nr. UNISA-990000786120203316
GIANNELLA, Mario  
Bologna : CLUEB, stampa 1998
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Alcohol, drugs, genes and clinical laboratory : an overview for healthcare and safety professionals / / Amitava Dasgupta, McGovern Medical School, The University of Texas, Health Science Center at Houston, Houston, TX, USA
Alcohol, drugs, genes and clinical laboratory : an overview for healthcare and safety professionals / / Amitava Dasgupta, McGovern Medical School, The University of Texas, Health Science Center at Houston, Houston, TX, USA
Autore DasGupta A (Amitava)
Pubbl/distr/stampa London : , : Academic Press, , [2017]
Descrizione fisica 1 online resource (x, 226 pages) : illustrations
Disciplina 615.78
Collana Gale eBooks
Soggetto topico Substance abuse - Genetic aspects
Alcoholism
Alcoholism - Genetic aspects
Drinking of alcoholic beverages
Drug abuse
Drug abuse - Genetic aspects
Drug testing
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Alcohol a double-edged sword -- 2. Drugs of abuse -- 3. Designer drugs including bath salts and spices -- 4. Combined alcohol and drug abuse -- 5. Link between environmental factors, personality factors, and addiction -- 6. Genetic polymorphisms of alcohol metabolizing enzymes associated with protection from or increased risk of alcohol abuse -- 7. Pharmacogenomics of abused drugs -- 8. Association between polymorphisms in genes encoding various receptors, transporters, and enzymes and alcohol/drug addiction -- 9. Methods of alcohol measurement -- 10. Laboratory methods for measuring drugs of abuse in urine -- 11. Analysis of drug abuse in serum, hair, oral fluid, sweat and meconium.
Record Nr. UNINA-9910583459003321
DasGupta A (Amitava)  
London : , : Academic Press, , [2017]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antidepressants : From Biogenic Amines to New Mechanisms of Action / / edited by Matthew Macaluso, Sheldon H. Preskorn
Antidepressants : From Biogenic Amines to New Mechanisms of Action / / edited by Matthew Macaluso, Sheldon H. Preskorn
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (xii, 442 pages) : illustrations (some color), charts
Disciplina 615
615.78
Collana Handbook of Experimental Pharmacology
Soggetto topico Pharmacology
Psychiatry
Neurosciences
Neuroscience
ISBN 9783030109493
3030109496
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part 1: Overview and General Principles -- 1. Impact, Diagnosis, Phenomenology, and Biology -- Part 2: The Past – from antiquity to 1970 including TCAs and MAOIs -- 2. Tricyclic Antidepressants and Monoamine Oxidase Inhibitors: Are They Too Old for a New Look? -- Part 3: The Present- 1970 to 2016 -- 3. Clinical Implications of the STAR*D Trial -- 4. Pharmacogenomics and Biomarkers of Depression -- 5. Therapeutic Drug Monitoring of Antidepressants -- 6. Selective Serotonin Reuptake Inhibitors -- 7. Serotonin and Norepinephrine Reuptake Inhibitors -- 8. Neurostimulation Therapies -- 9. Current Role of Herbal and Natural Preparations -- Part 4: The future -- 10. Role of Inflammation in Depression and Treatment Implications -- 11. NMDA Antagonists for Treatment-Resistant Depression -- 12. Drug Development in Psychiatry: The Long and Winding Road from Chance Discovery to Rational Development -- 13. Other Antidepressants -- Part 5: Use of Antidepressants in Special Populations -- 14. Use of Antidepressants in Patients with Co-occurring Depression and Substance Use Disorders -- 15. Treatment of Depression in Women -- 16. Management of Late-Life Depression -- 17. The Use of Antidepressants in Bipolar Depression.
Record Nr. UNINA-9910337937903321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antidepressants : perspectives, medical uses and health implications / / Sharon Jenkins, editor
Antidepressants : perspectives, medical uses and health implications / / Sharon Jenkins, editor
Pubbl/distr/stampa New York : , : Nova Biomedical, , 2017
Descrizione fisica 1 online resource (171 pages) : illustrations
Disciplina 615.78
Collana Pharmacology - Research, Safety Testing and Regulation
Soggetto topico Antidepressants
Depression, Mental
ISBN 1-5361-0398-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910155225203321
New York : , : Nova Biomedical, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The art and science of psychopharmacology : essential tools for treating anxiety, depression, bipolar disorder and psychosis / / Susan Marie
The art and science of psychopharmacology : essential tools for treating anxiety, depression, bipolar disorder and psychosis / / Susan Marie
Autore Marie Susan
Pubbl/distr/stampa Eau Claire, Wisconsin : , : PESI Publishing & Media, , [2020]
Descrizione fisica 1 online resource (158 pages)
Disciplina 615.78
Soggetto topico Psychopharmacology
Soggetto genere / forma Electronic books.
ISBN 1-68373-317-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910479855803321
Marie Susan  
Eau Claire, Wisconsin : , : PESI Publishing & Media, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The art and science of psychopharmacology : essential tools for treating anxiety, depression, bipolar disorder and psychosis / / Susan Marie
The art and science of psychopharmacology : essential tools for treating anxiety, depression, bipolar disorder and psychosis / / Susan Marie
Autore Marie Susan
Pubbl/distr/stampa Eau Claire, Wisconsin : , : PESI Publishing & Media, , [2020]
Descrizione fisica 1 online resource (158 pages)
Disciplina 615.78
Soggetto topico Psychopharmacology
ISBN 1-68373-317-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910794103303321
Marie Susan  
Eau Claire, Wisconsin : , : PESI Publishing & Media, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The art and science of psychopharmacology : essential tools for treating anxiety, depression, bipolar disorder and psychosis / / Susan Marie
The art and science of psychopharmacology : essential tools for treating anxiety, depression, bipolar disorder and psychosis / / Susan Marie
Autore Marie Susan
Pubbl/distr/stampa Eau Claire, Wisconsin : , : PESI Publishing & Media, , [2020]
Descrizione fisica 1 online resource (158 pages)
Disciplina 615.78
Soggetto topico Psychopharmacology
ISBN 1-68373-317-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910823106903321
Marie Susan  
Eau Claire, Wisconsin : , : PESI Publishing & Media, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Aspects of psychopharmacology / / edited by D.J. Sanger and D.E. Blackman
Aspects of psychopharmacology / / edited by D.J. Sanger and D.E. Blackman
Pubbl/distr/stampa Abingdon, Oxon : , : Routledge, , 2017
Descrizione fisica 1 online resource (240 pages) : illustrations, graphs
Disciplina 615.78
Altri autori (Persone) Blackmanderek E
SangerD. J
Collana Routledge Library Editions: Addictions
Soggetto topico Psychopharmacology
Psychotropic drugs
Substance abuse
ISBN 1-315-53605-6
1-315-53604-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Introduction to psychopharmacology and basic neuropharmacology / A.J. Greenshaw, D.J. Sanger and D.E. Blackman -- 2. Behavioural principles in psychopharmacology / James E. Barrett -- 3. Internal stimulus effects of drugs / I.P. Stolerman -- 4. Alcohol and alcoholism / Geoff Lowe -- 5. Social aspects of illegal drug use / Raymond Cochrane -- 6. Drugs and human memory / C.M. Smith -- 7. The use of drugs in psychiatry / P.E. Harrison-Read -- 8. Contemporary psychopharmacology : a review / D.J. Sanger and D.E. Blackman.
Record Nr. UNINA-9910136150103321
Abingdon, Oxon : , : Routledge, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Behavioral Neurobiology of GABAB Receptor Function / / edited by Styliani Vlachou, Kevin Wickman
Behavioral Neurobiology of GABAB Receptor Function / / edited by Styliani Vlachou, Kevin Wickman
Edizione [1st ed. 2022.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
Descrizione fisica 1 online resource (331 pages)
Disciplina 615.78
Collana Current Topics in Behavioral Neurosciences
Soggetto topico Pharmacology
Neurosciences
Psychiatry
Neuroscience
ISBN 3-030-91335-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Contents -- A Brief History and the Significance of the GABAB Receptor -- 1 Introduction -- 2 GABAB Receptor Structure, Function, and Distribution -- 3 GABAB Receptor Ligands: Agonists, Antagonists, and Allosteric Modulators -- 4 GABAB Receptors as Potential Therapeutic Targets -- 4.1 Drug and Alcohol Use Disorders -- 4.2 Pain and Analgesia -- 4.3 Anxiety and Mood Disorders -- 4.4 Neurodegeneration -- 4.5 Cognitive Processes in Neurodevelopment, Health and Disease -- 4.6 Other Conditions Outside the CNS -- 5 Conclusion -- References -- Structural Basis of GABAB Receptor Regulation and Signaling -- 1 Heterodimers Are the Minimal Functional Receptor Units -- 2 Signal Transduction in the Receptor Heterodimer -- 3 Auxiliary KCTD Subunits -- 4 SD-Interacting Proteins -- 5 Effector Channels -- 6 Additional Receptor-Associated Proteins -- 7 Concluding Remarks -- References -- Mechanisms and Regulation of Neuronal GABAB Receptor-Dependent Signaling -- 1 Introduction -- 2 GABABR Structure -- 2.1 Ligand Binding -- 2.2 Coupling to G Proteins -- 2.3 Cell Surface Trafficking -- 2.4 Alternative Splicing -- 2.5 Oligomerization -- 2.6 GABABR Signalosome -- 3 GABABR-Dependent Signaling in Neurons -- 3.1 GABABR Coupling to G Proteins -- 3.2 GABABR Regulation of Effectors -- 3.2.1 GIRK Channels -- 3.2.2 Voltage-Gated Ca2+ Channels -- 3.2.3 Adenylyl Cyclase -- 4 Regulation of GABABR-Dependent Signaling in Neurons -- 4.1 Desensitization -- 4.2 Phosphorylation -- 4.2.1 CaMKII -- 4.2.2 AMPK -- 4.2.3 PKA -- 4.2.4 PKC -- 4.3 Ubiquitination -- 4.4 KCTD Proteins -- 4.5 RGS Proteins -- 4.5.1 R7 RGS/Gβ5 -- 4.5.2 R4 RGS Proteins -- 4.5.3 RGS12 -- 5 Plasticity of GABABR-Dependent Signaling -- 5.1 Phosphorylation-Dependent Plasticity -- 5.2 Plasticity of 14-3-3 Proteins -- 5.3 Plasticity of RGS Regulation -- 6 Concluding Remarks -- References.
GABAB Receptor Chemistry and Pharmacology: Agonists, Antagonists, and Allosteric Modulators -- 1 Introduction -- 2 Brief History -- 3 Structure and Signaling -- 4 Molecular Diversity and Complexity -- 5 Agonists -- 6 Partial Agonists -- 7 Antagonists -- 8 Inverse Agonists -- 9 Allosteric Modulators -- 10 Probe Dependency -- 11 Biased Agonism/Functional Selectivity -- 12 GABAB Receptor-Targeted Pharmaceuticals -- 13 Concluding Remarks -- References -- GABAB Receptors and Drug Addiction: Psychostimulants and Other Drugs of Abuse -- 1 Introduction -- 2 GABABR Signaling in the Reward Circuit -- 2.1 The VTA Microcircuit -- 2.2 GABAergic Inputs to the VTA -- 3 Impact of Addictive Drugs on GABABR Signaling in the Reward Circuit -- 3.1 Psychostimulants -- 3.2 Nicotine -- 3.3 Opioids -- 3.4 Cannabis -- 3.5 Summary -- 4 Effects of Genetic Manipulations of GABABR on Animal Models of Drug Addiction -- 5 Effects of Pharmacological Manipulations on Animal Models of Drug Addiction: Agonists, Antagonists, and Positive Allosteric ... -- 5.1 Psychostimulants -- 5.1.1 Amphetamine and Methamphetamine -- 5.1.2 Cocaine -- 5.2 Nicotine -- 5.3 Opioids -- 5.4 Other Drugs/Reinforcers -- 5.5 Stress and Addiction -- 5.6 Summary -- 6 Clinical Studies of GABABR Modulators in Drug Addiction -- 7 Conclusions -- References -- GABAB Receptors and Alcohol Use Disorders: Preclinical Studies -- 1 GABAB Receptors and Alcohol Use Disorders: Preclinical Studies -- 2 Locomotor Activity -- 3 Place Conditioning -- 4 Alcohol Withdrawal Syndrome -- 5 Alcohol Drinking -- 5.1 Acquisition and Maintenance of Alcohol Drinking -- 5.2 Binge-Like Drinking -- 5.3 Relapse-Like Drinking -- 6 Operant Alcohol Self-Administration -- 6.1 Fixed Ratio (FR) Procedure -- 6.2 Progressive Ratio (PR) Procedure -- 6.3 Extinction and Reinstatement of Alcohol Seeking Procedures -- 6.4 Appetitive-Consummatory Procedures.
7 Discussion -- References -- GABAB Receptors and Alcohol Use Disorders: Clinical Studies -- 1 Introduction -- 2 Overview of Pharmacotherapies Modulating the GABAB Receptor -- 2.1 Baclofen -- 2.2 γ-Hydroxybutyric Acid -- 3 Treatment for Alcohol Withdrawal Syndrome -- 4 Relapse Prevention in Alcohol Use Disorders -- 4.1 Baclofen: Low-to-Moderate Doses -- 4.2 Baclofen: High-Doses -- 4.3 Specific Populations -- 4.3.1 Alcohol-Related Liver Disease -- 4.3.2 Comorbid Anxiety -- 5 Meta-Analyses Assessing Baclofen´s Efficacy -- 6 Laboratory Studies Evaluating Craving and Biobehavioural Effects of Baclofen -- 6.1 Functional Brain Activation Correlates with Baclofen -- 7 Polymorphisms Associated with Baclofen Treatment Response -- 8 Safety Concerns with Baclofen -- 9 Conclusions -- References -- GABAB Receptors and Pain -- 1 Introduction -- 1.1 Pain-Related Terminology -- 2 Expression and Function of GABAB Receptors in Nociceptive Pathways -- 2.1 GABAB Receptors in Nociceptors -- 2.1.1 GABAB Receptors in Peripheral Axon Endings of Nociceptors -- 2.1.2 GABAB Receptors in Central Axon Endings of Nociceptors -- 2.2 GABAB Receptors in Dorsal Horn Interneurons and Projection Neurons -- 2.3 GABAB Receptors in Supraspinal Areas -- 2.4 GABAB Receptors in Descending Pain Control Pathways -- 3 GABAB Receptors and Pathological Pain -- 3.1 GABAB Receptors and Inflammatory Pain -- 3.2 GABAB Receptors and Neuropathic Pain -- 4 GABAB Receptors as Target for Treating Chronic Pain -- 5 Conclusions -- References -- GABAB Receptors: Anxiety and Mood Disorders -- 1 Introduction -- 2 Role of the GABAB Receptor in the Modulation of Anxiety -- 2.1 Effects of GABAB Receptor Agonists and Positive Allosteric Modulators on Anxiety-Like Behaviour -- 2.2 Effects of GABAB Receptor Loss of Function and GABAB Receptor Antagonists on Anxiety-Like Behaviour.
3 Role of the GABAB Receptor in Depression and Antidepressant Action -- 3.1 Effects of GABAB Receptor Agonists on Depression-Like Behaviour -- 3.2 Effects of GABAB Receptor Blockade or Loss of Function on Depression-Like Behaviour -- 4 Clinical Evidence of the Role of GABAB Receptor in Mood Disorders -- 5 Conclusions and Perspectives -- References -- GABAB Receptors in Neurodegeneration -- 1 Introduction -- 2 GABAB Receptor and Its Effects -- 2.1 K+ Channels -- 2.2 Ca2+ Channels -- 2.3 Inhibition of Adenylate Cyclase -- 3 GABAA Receptors -- 4 GABAB in Neurodegenerative Diseases -- 4.1 GABAB in Alzheimer´s Disease -- 4.2 GABAB in Parkinson´s Disease -- 4.3 GABAB in Temporal Lobe Epilepsy -- 5 Conclusions -- References -- GABAB Receptors and Cognitive Processing in Health and Disease -- 1 Introduction -- 2 GABAB Receptors Mechanisms of Action -- 3 Effects of GABAB Receptors on Cognitive Processes: Learning and Memory -- 3.1 GABAB Receptors, LTP and Synaptic Plasticity -- 3.2 Active and Passive Avoidance Paradigms -- 3.3 Morris Water Maze (MWM) and Radial Arm Maze (RAM) -- 3.4 Working Memory Tasks -- 3.5 Novel-Object Recognition (NOR) and (Dis)Location (NOL) Tasks -- 3.6 Other Cognitive Tasks -- 4 GABABR Involvement in Cognitive Performance of Neurodevelopmental Conditions -- 4.1 GABABRs During Embryo-Foetal Development -- 4.2 Autism Spectrum Disorder (ASD) -- 4.3 Fragile X Syndrome (FXS) -- 4.4 Down´s Syndrome (DS) -- 5 Neurodegenerative Disorders -- 5.1 Alzheimer´s Disease (AD) -- 5.2 Epilepsy -- 5.3 Autoimmune Anti-GABAB Encephalitis and Cognitive Impairments -- 6 Conclusions -- References.
Record Nr. UNINA-9910522957003321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The Behavioral Neuroscience of Drug Discrimination / / edited by Joseph H. Porter, Adam J. Prus
The Behavioral Neuroscience of Drug Discrimination / / edited by Joseph H. Porter, Adam J. Prus
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (324 pages)
Disciplina 615.78
Collana Current Topics in Behavioral Neurosciences
Soggetto topico Neurosciences
Psychopharmacology
Behavioral sciences
Behavioral Sciences
ISBN 3-319-98561-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto From the Contents -- Preface -- Part 1. Overview -- Part 2. The Discriminative Stimulus Properties of Drugs -- Part 3. Approaches to Drug Discrimination.
Record Nr. UNINA-9910298420403321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
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