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Antibody-Drug Conjugates and Immunotoxins [[electronic resource] ] : From Pre-Clinical Development to Therapeutic Applications / / edited by Gail Lewis Phillips
| Antibody-Drug Conjugates and Immunotoxins [[electronic resource] ] : From Pre-Clinical Development to Therapeutic Applications / / edited by Gail Lewis Phillips |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Humana, , 2013 |
| Descrizione fisica | 1 online resource (369 p.) |
| Disciplina |
615.37
615.373 |
| Collana | Cancer Drug Discovery and Development |
| Soggetto topico |
Cancer research
Medicine Antibodies Cancer Research Biomedicine, general |
| ISBN |
1-283-93413-2
1-4614-5456-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Antibody Directed Delivery for Treatment of Cancer: Antibody Drug Conjugates and Immunotoxins -- Antibody-Drug Conjugate Development -- Components of ADC Development: Assay Methodologies and Challenges -- Clinical Pharmacology Strategies in the Development of Antibody-Drug Conjugates -- Predictive Biomarkers for Antibody-Drug Conjugates -- Factors Involved in the Design of Cytotoxic Payloads for Antibody-Drug Conjugates -- Linker Technology and Impact of Linker Design on ADC Properties -- Antibody-drug conjugates for the treatment of B-cell malignancies -- Targeting CD19 with SAR3419, an anti-CD19-Maytansinoid Conjugate for the Treatment of B Cell Malignancies -- Brentuximab Vedotin (SGN-35) for CD30 Positive Malignancies -- Trastuzumab Emtansine (T-DM1) for the Treatment of HER2-Positive Cancer -- CDX-011 (Glembatumumab Vedotin, CR011-vcMMAE) -- Case Study: An Antibody-Drug Conjugate Targeting MUC16 for Ovarian Cancer -- EphA2 Immunoconjugate -- Anti-PSMA Antibody-Drug Conjugates -- Targeting CD56 (NCAM)-expressing Neoplasms with Lorvotuzumab Mertansine -- Studies on the Metabolism of Antibody-Drug Conjugates -- Design, Development and Characterization of Recombinant Immunotoxins Targeting HER2/neu -- The Preclinical and Clinical Evaluation of VB6-845: An Immunotoxin with a De-Immunized Payload for the Systemic Treatment of Solid Tumors -- Index. |
| Record Nr. | UNINA-9910437996003321 |
| New York, NY : , : Springer New York : , : Imprint : Humana, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibody-mediated drug delivery systems [[electronic resource] ] : concepts, technology, and applications / / edited by Yashwant Pathak, Simon Benita
| Antibody-mediated drug delivery systems [[electronic resource] ] : concepts, technology, and applications / / edited by Yashwant Pathak, Simon Benita |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (542 p.) |
| Disciplina | 615.37 |
| Altri autori (Persone) |
PathakYashwant
BenitaSimon <1947-> |
| Soggetto topico |
Antibody-drug conjugates
Drug delivery systems |
| ISBN |
1-280-58983-3
9786613619662 1-118-22889-8 1-118-22901-0 1-118-22884-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Antibody mediated drug delivery systems : a general review and applications / Navdeep Kaur, Karthikeyan Subramani, and Y.V. Pathak -- Immunoliposomes for cardiovascular targeting / Tatyana Levchenko, William Hartner, and Vladimir P. Torchilin -- Antibody mediated drug delivery systems for breast cancer therapeutics / Leonor Munoz Alcivar and Y.V. Pathak -- Development of immunonconjugates for in vivo delivery : cancer diagnosis, imaging, and therapy / Arut Selvan -- Mathematical models of anti-TNF therapies and their correlation with tuberculosis / Simeone Marino ... [et al.] -- Targeted nanoparticles in radiotherapy / Misty Muscarella and Y.V. Pathak -- Electrically-enhanced delivery of drugs and conjugates for cancer treatment / Arut Selvan, Luca Campana, and Raji Sundararajan -- Characterization of mAb variants and glycosylation / Ting Zheng ... [et al.] -- Antibody mediated drug delivery system for lymphatic targeting treatment / Fang Wu, Hong Ding, and Zhirong Zhang -- Methods for nanoparticle conjugation to monoclonal antibodies (mAbs) / Junling Li and Chin K. Ng -- Single use systems in animal cell-based bioproduction / William G. Whitford -- Immunoliposomes for specific drug delivery / Manuela Calin -- Gene therapy targeting kidney diseases : routes & vehicles / Yoshitaka Isaka, Yoshitsugu Takabatake, and Hiromi Rakugi -- Detection of antibodies to polyethylene glycol polymers using a double antigen bridging immunogenicity ELISA / Yijuan Liu ... [et al.] -- Antibodies in nanomedicine and microimaging methods / Rakesh Sharma -- Methods for polymeric nanoparticle conjugation to mAb / Uyen Minh Le, Hieu Tran, and Y.V. Pathak -- Plant-derived antibodies for academic, industrial, and therapeutic application / Slavko Komarnytsk and Nikolai Borisjuk -- Monoclonal antibodies as biopharmaceuticals / Girish J. Kotwal -- Pulmonary targeting of nanoparticles and monoclonal antibodies (mAb) / Weiyuan Chang -- Antibody mediated arthritis and new therapeutic avenues / Kutty Selva Nandakumar -- Immuno-nanoparticles for nuclear imaging and radiotherapy / Oren Giladi and Simon Benita -- Monoclonal antibodies in the treatment of asthma / Glenn J. Whelan. |
| Record Nr. | UNINA-9910141297903321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibody-mediated drug delivery systems [[electronic resource] ] : concepts, technology, and applications / / edited by Yashwant Pathak, Simon Benita
| Antibody-mediated drug delivery systems [[electronic resource] ] : concepts, technology, and applications / / edited by Yashwant Pathak, Simon Benita |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (542 p.) |
| Disciplina | 615.37 |
| Altri autori (Persone) |
PathakYashwant
BenitaSimon <1947-> |
| Soggetto topico |
Antibody-drug conjugates
Drug delivery systems |
| ISBN |
1-280-58983-3
9786613619662 1-118-22889-8 1-118-22901-0 1-118-22884-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Antibody mediated drug delivery systems : a general review and applications / Navdeep Kaur, Karthikeyan Subramani, and Y.V. Pathak -- Immunoliposomes for cardiovascular targeting / Tatyana Levchenko, William Hartner, and Vladimir P. Torchilin -- Antibody mediated drug delivery systems for breast cancer therapeutics / Leonor Munoz Alcivar and Y.V. Pathak -- Development of immunonconjugates for in vivo delivery : cancer diagnosis, imaging, and therapy / Arut Selvan -- Mathematical models of anti-TNF therapies and their correlation with tuberculosis / Simeone Marino ... [et al.] -- Targeted nanoparticles in radiotherapy / Misty Muscarella and Y.V. Pathak -- Electrically-enhanced delivery of drugs and conjugates for cancer treatment / Arut Selvan, Luca Campana, and Raji Sundararajan -- Characterization of mAb variants and glycosylation / Ting Zheng ... [et al.] -- Antibody mediated drug delivery system for lymphatic targeting treatment / Fang Wu, Hong Ding, and Zhirong Zhang -- Methods for nanoparticle conjugation to monoclonal antibodies (mAbs) / Junling Li and Chin K. Ng -- Single use systems in animal cell-based bioproduction / William G. Whitford -- Immunoliposomes for specific drug delivery / Manuela Calin -- Gene therapy targeting kidney diseases : routes & vehicles / Yoshitaka Isaka, Yoshitsugu Takabatake, and Hiromi Rakugi -- Detection of antibodies to polyethylene glycol polymers using a double antigen bridging immunogenicity ELISA / Yijuan Liu ... [et al.] -- Antibodies in nanomedicine and microimaging methods / Rakesh Sharma -- Methods for polymeric nanoparticle conjugation to mAb / Uyen Minh Le, Hieu Tran, and Y.V. Pathak -- Plant-derived antibodies for academic, industrial, and therapeutic application / Slavko Komarnytsk and Nikolai Borisjuk -- Monoclonal antibodies as biopharmaceuticals / Girish J. Kotwal -- Pulmonary targeting of nanoparticles and monoclonal antibodies (mAb) / Weiyuan Chang -- Antibody mediated arthritis and new therapeutic avenues / Kutty Selva Nandakumar -- Immuno-nanoparticles for nuclear imaging and radiotherapy / Oren Giladi and Simon Benita -- Monoclonal antibodies in the treatment of asthma / Glenn J. Whelan. |
| Record Nr. | UNINA-9910809538703321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antiviral drugs / John S. Driscoll
| Antiviral drugs / John S. Driscoll |
| Autore | DRISCOLL, J.S. |
| Pubbl/distr/stampa | Burlington : Ashgate, copyr. 2002 |
| Descrizione fisica | XXV, 174 p. ; 25 cm |
| Disciplina | 615.37 |
| Soggetto topico |
Chemioterapici antivirali
Malattie da virus - Terapia |
| ISBN | 0-566-08310-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990001132150203316 |
DRISCOLL, J.S.
|
||
| Burlington : Ashgate, copyr. 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Bacterial vaccines and local immunity : proceedings of Sclavo international conference : Siena, Italy, 17-19 November, 1986 / [a cura di] Aldo Tagliabue, Rino Rappuoli, Sergio E. Piazzi
| Bacterial vaccines and local immunity : proceedings of Sclavo international conference : Siena, Italy, 17-19 November, 1986 / [a cura di] Aldo Tagliabue, Rino Rappuoli, Sergio E. Piazzi |
| Pubbl/distr/stampa | Siena : Sclavo, 1986 |
| Descrizione fisica | 428 p. : ill. ; 24 cm |
| Disciplina | 615.37 |
| Collana | Annali Sclavo |
| Soggetto non controllato |
Vaccinazioni
Immunità |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNINA-990008851910403321 |
| Siena : Sclavo, 1986 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Basic and Clinical Aspects of Interferon Gamma / / edited by Hridayesh Prakash
| Basic and Clinical Aspects of Interferon Gamma / / edited by Hridayesh Prakash |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2022 |
| Descrizione fisica | 1 online resource (130 pages) |
| Disciplina | 615.37 |
| Soggetto topico | Interferon - Therapeutic use |
| ISBN | 1-80355-886-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Perspective Chapter: Macrophages Plasticity and Immune Metabolism -- 2. Interferons Horizon Therapeutics -- 3. Perspective Chapter: Impact of Interferon Alpha/Beta in the Management of Chronic Myeloproliferative Disorders -- 4. Perspective Chapter: Interferon-Gamma in Natural Defence and Prevention of Leprosy -- 5. Perspective Chapter: The Role of Interferon Gamma in Clinical Medicine -- 6. Interferon and HPA Axis: Impact on Neuroimmunological Perturbations. |
| Record Nr. | UNINA-9910633968003321 |
| London : , : IntechOpen, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Basic and Clinical Aspects of Interferon Gamma / / edited by Hridayesh Prakash
| Basic and Clinical Aspects of Interferon Gamma / / edited by Hridayesh Prakash |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2022 |
| Descrizione fisica | 1 online resource (ix, 130 pages) : illustrations |
| Disciplina | 615.37 |
| Soggetto topico |
Interferon - Therapeutic use
Interleukin-18 Immunology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Perspective Chapter: Macrophages Plasticity and Immune Metabolism -- 2. Interferons Horizon Therapeutics -- 3. Perspective Chapter: Impact of Interferon Alpha/Beta in the Management of Chronic Myeloproliferative Disorders -- 4. Perspective Chapter: Interferon-Gamma in Natural Defence and Prevention of Leprosy -- 5. Perspective Chapter: The Role of Interferon Gamma in Clinical Medicine -- 6. Interferon and HPA Axis: Impact on Neuroimmunological Perturbations. |
| Record Nr. | UNINA-9910687993303321 |
| London : , : IntechOpen, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biotherapy
| Biotherapy |
| Pubbl/distr/stampa | [Dordrecht], : Kluwer Academic Publishers |
| Disciplina | 615.37 |
| Soggetto topico |
Biological products - Therapeutic use
Biological response modifiers Immunotherapy Biological Factors - therapeutic use Biothérapie Immunomodulateurs Immunothérapie |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| ISSN | 1573-8280 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996207843003316 |
| [Dordrecht], : Kluwer Academic Publishers | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Current Understanding and Treatment of Gliomas [[electronic resource] /] / edited by Jeffrey Raizer, Andrew Parsa
| Current Understanding and Treatment of Gliomas [[electronic resource] /] / edited by Jeffrey Raizer, Andrew Parsa |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (186 p.) |
| Disciplina |
615.3
615.37 |
| Collana | Cancer Treatment and Research |
| Soggetto topico |
Oncology
Neurology Radiotherapy Oncology Neurology |
| ISBN | 3-319-12048-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Epidemiology of gliomas -- Glioma Biology and molecular markers -- Surgery for gliomas -- Radiation for gliomas -- Current treatment of low grade gliomas -- Current treatment of AG -- Current treatment of GBM -- Novel Chemotherapy approaches in gliomas -- Vaccine and Immunotherapy approaches -- Malignant gliomas in elderly -- Palliative care for glioma patients. |
| Record Nr. | UNINA-9910300199703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Development of Antibody-Based Therapeutics [[electronic resource] ] : Translational Considerations & Challenges / / edited by Mohammad A. Tabrizi, Gadi G. Bornstein, Scott L. Klakamp
| Development of Antibody-Based Therapeutics [[electronic resource] ] : Translational Considerations & Challenges / / edited by Mohammad A. Tabrizi, Gadi G. Bornstein, Scott L. Klakamp |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Adis, , 2018 |
| Descrizione fisica | 1 online resource (255 pages) |
| Disciplina | 615.37 |
| Soggetto topico |
Pharmacy
Toxicology Biochemistry Pharmacology/Toxicology Biochemistry, general |
| ISBN | 981-13-0496-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Introduction -- 2. Translational Considerations and Challenges: An Overview -- 3. Considerations for Construct and Affinity Design Goals -- 4. Epitope Characterization and Isotype Selection -- 5. Biophysical Considerations for Development of Antibody-Based Therapeutics -- 6. Novel Technologies for Generation of Bispecific Constructs -- 7. Stimulus-Response Mechanisms: An Overview -- 8. Evaluation of Tumor Growth Inhibition in Preclinical Tumor Models –A Quantitative Approach -- 9. Application of Proof-of-Mechanism Biomarkers (POM) in Design and Development of Biologics Modalities -- 10. Antibody Drug Conjugates: Translational Considerations -- 11. Application of PK-PD Modeling and Simulation Approaches for Immuno-Oncology Drugs -- 12. Translational Biomarkers: Application in the Clinical Development of Combination Therapies. |
| Record Nr. | UNINA-9910300308503321 |
| Singapore : , : Springer Singapore : , : Imprint : Adis, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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