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Antisense oligodeoxynucleotides and antisense RNA : novel pharmacological and therapeutic agents / edited by Benjamin Weiss
| Antisense oligodeoxynucleotides and antisense RNA : novel pharmacological and therapeutic agents / edited by Benjamin Weiss |
| Pubbl/distr/stampa | Boca Raton [etc.] : CRC Press, copyr.1997 |
| Descrizione fisica | 252 p. : ill. ; 26 cm |
| Disciplina | 615.31 |
| Collana | Pharmacology and toxicology, : Basic and clinical aspects |
| Soggetto topico | Acidi nucleici - Impiego terapeutico |
| ISBN | 0-8493-8552-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990000085020203316 |
| Boca Raton [etc.] : CRC Press, copyr.1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Gli antistaminici antagonisti del recettore H1 / Elide A. Pastorello, Giuseppe Vighi ; Editor: Claudio Ortolani
| Gli antistaminici antagonisti del recettore H1 / Elide A. Pastorello, Giuseppe Vighi ; Editor: Claudio Ortolani |
| Autore | Pastorello, Elide A. |
| Pubbl/distr/stampa | Milano : Mediamix Edizioni Scientifiche, c1991 |
| Descrizione fisica | 109 p. : ill. ; 24 cm |
| Disciplina | 615.31 |
| Altri autori (Persone) | Vighi, Giuseppe |
| Soggetto non controllato | Antistaminici |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNINA-990008310440403321 |
Pastorello, Elide A.
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| Milano : Mediamix Edizioni Scientifiche, c1991 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oligonucleotides as therapeutic agents : Atti del convegno tenuto a Londra nel 1997
| Oligonucleotides as therapeutic agents : Atti del convegno tenuto a Londra nel 1997 |
| Pubbl/distr/stampa | Chichester [etc.] : J. Wiley & sons, 1997 |
| Descrizione fisica | IX, 250 p. ; 24 cm |
| Disciplina | 615.31 |
| Collana | Ciba foundation symposium |
| Soggetto topico |
Medicinali sintetici
Acidi nucleici |
| ISBN | 0-471-97279-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990001187930203316 |
| Chichester [etc.] : J. Wiley & sons, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Oligonucleotides as therapeutic agents [[electronic resource] /] / [editors, Derek J. Chadwick (Organizer) and Gail Cardew]
| Oligonucleotides as therapeutic agents [[electronic resource] /] / [editors, Derek J. Chadwick (Organizer) and Gail Cardew] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1997 |
| Descrizione fisica | 1 online resource (262 p.) |
| Disciplina |
615
615.31 |
| Altri autori (Persone) |
ChadwickDerek
CardewGail |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Oligonucleotides - Therapeutic use
Antisense nucleic acids - Therapeutic use |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-34805-1
9786612348051 0-470-51539-2 0-470-51540-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS; Contents; Participants; Introduction; Oligoncleotide analogues: an overview; Phosphorothioate oligodeox ynucleotides: large-scale synthesis and analysis, impurity characterization, and the effects of phosphorus stereochemistry; Discovering antisense reagents by hybridization of RNA to oligonucleotide arrays; Pharrnacokinetics of oligonucleotides in cell culture; Pharrnacokinetics of oligonucleotides; Controversies in the cellular pharmacology of oligodeox ynucleotides; Sequence-specific control of gene expression by antigene and clamp oligonucleotides
First- and second-generation antisense oligonucleotide inhibitors targeted against human c-raf kinaseDifferential oligonucleotide activity in cell culture versus mouse models; Structure-activity relationships in cell culture; Progress in antisense therapeutics discovery and development; Oligonucleotide therapeutics for human leukemia; Therapeutic applications of catalytic antisense RNAs (ribozymes); Exogenous application of riboaymes for inhibiting gene expression; Efficient process technologies for the preparation of oligonucleotides In vivo production of oligodeoxyribonucleotides of specific sequences: application to antisense DNASummary; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144011403321 |
| Chichester ; ; New York, : Wiley, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Oligonucleotides as therapeutic agents [[electronic resource] /] / [editors, Derek J. Chadwick (Organizer) and Gail Cardew]
| Oligonucleotides as therapeutic agents [[electronic resource] /] / [editors, Derek J. Chadwick (Organizer) and Gail Cardew] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1997 |
| Descrizione fisica | 1 online resource (262 p.) |
| Disciplina |
615
615.31 |
| Altri autori (Persone) |
ChadwickDerek
CardewGail |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Oligonucleotides - Therapeutic use
Antisense nucleic acids - Therapeutic use |
| ISBN |
1-282-34805-1
9786612348051 0-470-51539-2 0-470-51540-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS; Contents; Participants; Introduction; Oligoncleotide analogues: an overview; Phosphorothioate oligodeox ynucleotides: large-scale synthesis and analysis, impurity characterization, and the effects of phosphorus stereochemistry; Discovering antisense reagents by hybridization of RNA to oligonucleotide arrays; Pharrnacokinetics of oligonucleotides in cell culture; Pharrnacokinetics of oligonucleotides; Controversies in the cellular pharmacology of oligodeox ynucleotides; Sequence-specific control of gene expression by antigene and clamp oligonucleotides
First- and second-generation antisense oligonucleotide inhibitors targeted against human c-raf kinaseDifferential oligonucleotide activity in cell culture versus mouse models; Structure-activity relationships in cell culture; Progress in antisense therapeutics discovery and development; Oligonucleotide therapeutics for human leukemia; Therapeutic applications of catalytic antisense RNAs (ribozymes); Exogenous application of riboaymes for inhibiting gene expression; Efficient process technologies for the preparation of oligonucleotides In vivo production of oligodeoxyribonucleotides of specific sequences: application to antisense DNASummary; Index of contributors; Subject index |
| Record Nr. | UNISA-996197617603316 |
| Chichester ; ; New York, : Wiley, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Oligonucleotides as therapeutic agents [[electronic resource] /] / [editors, Derek J. Chadwick (Organizer) and Gail Cardew]
| Oligonucleotides as therapeutic agents [[electronic resource] /] / [editors, Derek J. Chadwick (Organizer) and Gail Cardew] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1997 |
| Descrizione fisica | 1 online resource (262 p.) |
| Disciplina |
615
615.31 |
| Altri autori (Persone) |
ChadwickDerek
CardewGail |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Oligonucleotides - Therapeutic use
Antisense nucleic acids - Therapeutic use |
| ISBN |
1-282-34805-1
9786612348051 0-470-51539-2 0-470-51540-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS; Contents; Participants; Introduction; Oligoncleotide analogues: an overview; Phosphorothioate oligodeox ynucleotides: large-scale synthesis and analysis, impurity characterization, and the effects of phosphorus stereochemistry; Discovering antisense reagents by hybridization of RNA to oligonucleotide arrays; Pharrnacokinetics of oligonucleotides in cell culture; Pharrnacokinetics of oligonucleotides; Controversies in the cellular pharmacology of oligodeox ynucleotides; Sequence-specific control of gene expression by antigene and clamp oligonucleotides
First- and second-generation antisense oligonucleotide inhibitors targeted against human c-raf kinaseDifferential oligonucleotide activity in cell culture versus mouse models; Structure-activity relationships in cell culture; Progress in antisense therapeutics discovery and development; Oligonucleotide therapeutics for human leukemia; Therapeutic applications of catalytic antisense RNAs (ribozymes); Exogenous application of riboaymes for inhibiting gene expression; Efficient process technologies for the preparation of oligonucleotides In vivo production of oligodeoxyribonucleotides of specific sequences: application to antisense DNASummary; Index of contributors; Subject index |
| Record Nr. | UNINA-9910830621203321 |
| Chichester ; ; New York, : Wiley, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Perspectives in nucleoside and nucleic acid chemistry / M. Volkan Kisakurek, Helmut Rosemeyer (eds.)
| Perspectives in nucleoside and nucleic acid chemistry / M. Volkan Kisakurek, Helmut Rosemeyer (eds.) |
| Pubbl/distr/stampa | New York : Wiley-VCH, copyr. 2000 |
| Descrizione fisica | 420 p. : ill. ; 20 cm. |
| Disciplina | 615.31 |
| Soggetto non controllato |
Nucleoside
Acido nucleico |
| ISBN | 3-906390-21-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990000389810203316 |
| New York : Wiley-VCH, copyr. 2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Salicylic acid : a versatile plant growth regulator / / Shamsul Hayat, Husna Siddiqui, Christos A. Damalas
| Salicylic acid : a versatile plant growth regulator / / Shamsul Hayat, Husna Siddiqui, Christos A. Damalas |
| Autore | Hayat Shamsul |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (309 pages) |
| Disciplina | 615.31 |
| Soggetto topico |
Salicylic acid - Physiological effect
Plant hormones - Analysis Àcid salicílic Creixement (Plantes) |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-79229-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910768179403321 |
|
Hayat Shamsul
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| Cham, Switzerland : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthetic multivalent molecules [[electronic resource] ] : concepts and biomedical applications / / Seok-ki Choi
| Synthetic multivalent molecules [[electronic resource] ] : concepts and biomedical applications / / Seok-ki Choi |
| Autore | Choi Seok-ki <1964-> |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2004 |
| Descrizione fisica | 1 online resource (446 p.) |
| Disciplina |
615.31
615/.31 |
| Soggetto topico |
Multivalent molecules - Synthesis
Multivalent molecules - Design Multivalent molecules - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-54191-1
9786610541911 0-471-57770-7 0-471-57890-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
SYNTHETIC MULTIVALENT MOLECULES; CONTENTS; Preface; Notes for Organization and Classification; Abbreviations; 1 Introduction; 1.1 Nomenclature and Definitions; 1.1.1 Valency; 1.1.2 Linkers; 1.1.3 Scaffolds; 1.1.4 Ligand Density; 1.1.5 Homo- and Heterovalent Molecules; 1.2 Mechanistic Aspects of Multivalent Interaction; 1.2.1 Affinity Constant and Avidity; 1.2.2 Thermodynamics; 1.2.3 Kinetics; 1.2.4 Steric Effects; 1.3 Biological Roles of Multivalent Ligands; 2 Multivalent Molecules Applied to Viral Targets; 2.1 Influenza Virus; 2.1.1 Hemagglutinin; 2.1.1.1 Divalent Sialic Acid
2.1.1.2 Tetravalent Sialoside2.1.1.3 Dendrimers Presenting Sialosides; 2.1.1.4 Sialic Acid Displayed in Liposomes; 2.1.1.5 Polymerized Liposome Presenting Sialic Acid; 2.1.1.6 Sialic Acid in Langmuir-Blodget Monolayers; 2.1.1.7 Sialic Acid Presented on Biopolymer Surfaces; 2.1.1.8 Poly(acrylamide) Presenting Sialosides; 2.1.1.9 Poly(acrylic acid) Presenting Sialosides; 2.1.1.10 Poly(acrylamide) Presenting C-Sialosides; 2.1.1.11 Postmodification of Activated Polymers; 2.1.1.12 Modes of Action of Polymeric Sialosides; 2.1.1.13 OPTCOL Assay; 2.1.1.14 ter-Poly(acrylic acid) Presenting Sialosides 2.1.1.15 Poly(glutamic acid) Presenting Lysogangliosides2.1.1.16 Poly(glutamic acid) Bearing Sialic Acid-Containing Trisaccharides; 2.1.1.17 Poly(acrylamide) Bearing Sialic Acid Linked at the C(4) Position; 2.1.1.18 Poly(acrylamide) Tethering 9-O-Acetylsialosides; 2.1.1.19 Neoglycoprotein Displaying Sialic Acids; 2.1.1.20 Natural b-Inhibitors; 2.1.2 Neuraminidase; 2.1.2.1 Poly(glutamic acid) Presenting NA Inhibitors; 2.2 Human Immunodeficiency Virus; 2.2.1 HIV-1 Protease; 2.2.1.1 Divalent Terminal Peptides; 2.2.2 HIV-1 Reverse Transcriptase; 2.2.2.1 Heterodimers Composed of NRTI and NNRTI 2.2.3 Glycoprotein 120 (gp120) on Viral Surfaces2.2.3.1 Neoglycoprotein-Displaying CD4 Peptide; 2.2.3.2 Galactosyl Ceramide Immobilized on Viral Surfaces; 2.2.3.3 Multivalent Anions; 2.2.3.4 Bivalent Antagonists of CXCR4; 2.2.4 Surface Carbohydrates on HIV; 2.2.4.1 Oligomannose Sugars Present on gp120; 2.2.4.2 Modes of CVN Recognition; 2.3 Rotavirus; 2.4 Polyoma Virus; 2.5 Picorna Virus; 2.6 Respiratory Syncytial Virus; 2.7 Dengue Virus; 2.8 Nucleic Acids of Viruses; 2.8.1 RNA-Protein Interactions; 2.8.1.1 Neomycin B Linked to Acridine; 2.8.1.2 Neamine Linked to Pyrene-Carboxylic Acid 2.8.2 RNA-Enzyme Interactions2.8.3 Binders to the Minor Groove of Viral DNA; 2.8.3.1 Hairpin-Shaped Polyamide Dimers; 2.8.3.2 H-Shaped Polyamide Dimers; 2.8.3.3 Naturally Occurring Dimers; 2.9 Synthetic Multivalent Vaccines; 2.9.1 Peptide-Based Anti-influenza Vaccines; 2.9.2 Gp41-Based Anti-HIV Vaccine; 2.9.3 Peptide-Based Anti-FMDV Vaccines; 3 Multivalent Molecules Applied to Bacterial Targets; 3.1 Targets in Bacterial Cell Membranes; 3.1.1 D-Ala-D-Ala Peptide Precursors; 3.1.1.1 Mode of Action by Antibiotics of the Vancomycin Class; 3.1.1.2 Dimerization of Glycopeptide Antibiotics 3.1.1.3 Di- and Trivalent Vancomycin |
| Record Nr. | UNINA-9910146077703321 |
|
Choi Seok-ki <1964->
|
||
| Hoboken, N.J., : Wiley, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Synthetic multivalent molecules [[electronic resource] ] : concepts and biomedical applications / / Seok-ki Choi
| Synthetic multivalent molecules [[electronic resource] ] : concepts and biomedical applications / / Seok-ki Choi |
| Autore | Choi Seok-ki <1964-> |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2004 |
| Descrizione fisica | 1 online resource (446 p.) |
| Disciplina |
615.31
615/.31 |
| Soggetto topico |
Multivalent molecules - Synthesis
Multivalent molecules - Design Multivalent molecules - Physiological effect |
| ISBN |
1-280-54191-1
9786610541911 0-471-57770-7 0-471-57890-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
SYNTHETIC MULTIVALENT MOLECULES; CONTENTS; Preface; Notes for Organization and Classification; Abbreviations; 1 Introduction; 1.1 Nomenclature and Definitions; 1.1.1 Valency; 1.1.2 Linkers; 1.1.3 Scaffolds; 1.1.4 Ligand Density; 1.1.5 Homo- and Heterovalent Molecules; 1.2 Mechanistic Aspects of Multivalent Interaction; 1.2.1 Affinity Constant and Avidity; 1.2.2 Thermodynamics; 1.2.3 Kinetics; 1.2.4 Steric Effects; 1.3 Biological Roles of Multivalent Ligands; 2 Multivalent Molecules Applied to Viral Targets; 2.1 Influenza Virus; 2.1.1 Hemagglutinin; 2.1.1.1 Divalent Sialic Acid
2.1.1.2 Tetravalent Sialoside2.1.1.3 Dendrimers Presenting Sialosides; 2.1.1.4 Sialic Acid Displayed in Liposomes; 2.1.1.5 Polymerized Liposome Presenting Sialic Acid; 2.1.1.6 Sialic Acid in Langmuir-Blodget Monolayers; 2.1.1.7 Sialic Acid Presented on Biopolymer Surfaces; 2.1.1.8 Poly(acrylamide) Presenting Sialosides; 2.1.1.9 Poly(acrylic acid) Presenting Sialosides; 2.1.1.10 Poly(acrylamide) Presenting C-Sialosides; 2.1.1.11 Postmodification of Activated Polymers; 2.1.1.12 Modes of Action of Polymeric Sialosides; 2.1.1.13 OPTCOL Assay; 2.1.1.14 ter-Poly(acrylic acid) Presenting Sialosides 2.1.1.15 Poly(glutamic acid) Presenting Lysogangliosides2.1.1.16 Poly(glutamic acid) Bearing Sialic Acid-Containing Trisaccharides; 2.1.1.17 Poly(acrylamide) Bearing Sialic Acid Linked at the C(4) Position; 2.1.1.18 Poly(acrylamide) Tethering 9-O-Acetylsialosides; 2.1.1.19 Neoglycoprotein Displaying Sialic Acids; 2.1.1.20 Natural b-Inhibitors; 2.1.2 Neuraminidase; 2.1.2.1 Poly(glutamic acid) Presenting NA Inhibitors; 2.2 Human Immunodeficiency Virus; 2.2.1 HIV-1 Protease; 2.2.1.1 Divalent Terminal Peptides; 2.2.2 HIV-1 Reverse Transcriptase; 2.2.2.1 Heterodimers Composed of NRTI and NNRTI 2.2.3 Glycoprotein 120 (gp120) on Viral Surfaces2.2.3.1 Neoglycoprotein-Displaying CD4 Peptide; 2.2.3.2 Galactosyl Ceramide Immobilized on Viral Surfaces; 2.2.3.3 Multivalent Anions; 2.2.3.4 Bivalent Antagonists of CXCR4; 2.2.4 Surface Carbohydrates on HIV; 2.2.4.1 Oligomannose Sugars Present on gp120; 2.2.4.2 Modes of CVN Recognition; 2.3 Rotavirus; 2.4 Polyoma Virus; 2.5 Picorna Virus; 2.6 Respiratory Syncytial Virus; 2.7 Dengue Virus; 2.8 Nucleic Acids of Viruses; 2.8.1 RNA-Protein Interactions; 2.8.1.1 Neomycin B Linked to Acridine; 2.8.1.2 Neamine Linked to Pyrene-Carboxylic Acid 2.8.2 RNA-Enzyme Interactions2.8.3 Binders to the Minor Groove of Viral DNA; 2.8.3.1 Hairpin-Shaped Polyamide Dimers; 2.8.3.2 H-Shaped Polyamide Dimers; 2.8.3.3 Naturally Occurring Dimers; 2.9 Synthetic Multivalent Vaccines; 2.9.1 Peptide-Based Anti-influenza Vaccines; 2.9.2 Gp41-Based Anti-HIV Vaccine; 2.9.3 Peptide-Based Anti-FMDV Vaccines; 3 Multivalent Molecules Applied to Bacterial Targets; 3.1 Targets in Bacterial Cell Membranes; 3.1.1 D-Ala-D-Ala Peptide Precursors; 3.1.1.1 Mode of Action by Antibiotics of the Vancomycin Class; 3.1.1.2 Dimerization of Glycopeptide Antibiotics 3.1.1.3 Di- and Trivalent Vancomycin |
| Record Nr. | UNINA-9910830426003321 |
|
Choi Seok-ki <1964->
|
||
| Hoboken, N.J., : Wiley, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
