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Advances in natural products discovery / / Ana Rita Gomes, Teresa Rocha-Santos, and Armando Duarte (Department of Chemistry, University of Aveiro, Campus de Santiago, Aveiro, Portugal), editors
| Advances in natural products discovery / / Ana Rita Gomes, Teresa Rocha-Santos, and Armando Duarte (Department of Chemistry, University of Aveiro, Campus de Santiago, Aveiro, Portugal), editors |
| Pubbl/distr/stampa | Hauppauge, New York : , : Nova Science Publishers, Incorporated, , [2017] |
| Descrizione fisica | 1 online resource (311 pages) : illustrations |
| Disciplina | 615.3 |
| Collana | Chemistry research and applications |
| Soggetto topico | Natural products |
| ISBN | 1-5361-0101-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910150311503321 |
| Hauppauge, New York : , : Nova Science Publishers, Incorporated, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in protein and peptide sciences . Volume 1 / / Ben M. Dunn, editor
| Advances in protein and peptide sciences . Volume 1 / / Ben M. Dunn, editor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Sharjah : , : Bentham Science Publishers, , 2013 |
| Descrizione fisica | 1 online resource (911 p.) |
| Disciplina | 615.3 |
| Altri autori (Persone) | DunnBen M |
| Collana | Advances in Protein and Peptide Sciences |
| Soggetto topico |
Proteins
Peptides |
| ISBN | 1-60805-487-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Title; EUL; Contents; Foreword; Preface; List of Contributors; Section I; Chapter 01; Chapter 03; Chapter 04; Section II; Chapter 05; Chapter 06; Chapter 07; Section III; Chapter 08; Chapter 09; Chapter 10; Chapter 11; Chapter 12; Section IV; Chapter 13; Chapter 14; Chapter 15; Chapter 16; Chapter 17; Chapter 18; Chapter 19; Index |
| Record Nr. | UNINA-9910820288303321 |
| Sharjah : , : Bentham Science Publishers, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds [[electronic resource] /] / edited by Evandro Fei Fang, Tzi Bun Ng
| Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds [[electronic resource] /] / edited by Evandro Fei Fang, Tzi Bun Ng |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (423 p.) |
| Disciplina |
615.3
615.321 |
| Soggetto topico |
Cancer research
Apoptosis Medicine Molecular biology Pharmacology Cancer Research Biomedicine, general Molecular Medicine Pharmacology/Toxicology |
| ISBN | 94-007-6214-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | PREFACE -- PART I. Lectins: From biological recognition molecules to variable medicinal applications -- Lectins: Personal Comments of Nathan Sharon Taken from His Memoirs (Translation from Hebrew) .-The History of Lectinology -- Animal and Human Lectins -- Lectins of Marine Origin and their Clinical Applications -- Medicinal applications of plant lectins -- PART II Structural and functional insights into medicinal ribonucleases -- Plant nucleases from nuclease I family: their properties and antitumor potential -- Bovine Seminal Ribonuclease and its special features: when two is better than one -- PART III The perspectives for ribosome inactivating proteins: unveiling the working mechanisms and potential medicinal benefits -- The Discovery of MAP30 and Elucidation of its Medicinal Activities -- Ribosome Inactivating Proteins from Plants: Biological Properties and their Use in Experimental Therapy -- Current status & Biomedical applications of Ribosome-inactivating proteins -- PART IV The research history of protease inhibitors and their health implications -- The Health Benefits of the Bowman-Birk Inhibitor -- Peptidic inhibitors of serine proteinases of plant origin -- Anti-tumor effect of synthetic serine protease inhibitor.- A landscape of the health benefits of different natural protease inhibitors -- PART V Plethora of health benefits from small molecules: From bench-top to clinical settings -- Autophagy upregulation as a therapeutic strategy for neurodegenerative diseases -- Rapamycin – current and future uses -- Eating, drinking, smoking and cancer prevention: a focus on acetaldehyde -- The use of edible mushroom water soluble polysaccharides in the treatment and prevention of chronic diseases: a mechanistic approach -- Essential Oil Constituents: Biodiversity and their Applicability for Cancer Therapy -- PART VI Medicinal compounds from the garden: a bird’s eye view of one mushroom, one fruit, one insect, and others -- Recent research on pharmacological activities of the medicinal fungus Cordyceps sinensis -- The bitter fruit with sweet health benefits:A comprehensive synopsis of recent research progress on medicinal properties of Momordica charantia -- Bioactive constituents of the silk worm Bombyx mori -- Proteins with anticancer and antimicobial activities from mammals, submammalian vertebrates and invertebrates -- Defense proteins with antiproliferative and antimicrobial activities from fungi and bacteria -- PART VII Modernizing investigations of traditional Chinese medicine at the molecular level -- The role of the GP-TCM Research Association to modernization and globalization of Traditional Chinese Medicine.- High-throughput screening in traditional Chinese medicine-based drug discovery -- PART VIII Questions and future perspectives -- Achievements, questions arising and future outlook on the path to discover new medicinal compounds. Index. |
| Record Nr. | UNINA-9910739422303321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biotecnologie farmaceutiche / Daan J. A. Crommelin, Robert D. Sindelar ; [trad. di Aroldo U. Magno]
| Biotecnologie farmaceutiche / Daan J. A. Crommelin, Robert D. Sindelar ; [trad. di Aroldo U. Magno] |
| Pubbl/distr/stampa | Bologna : Zanichelli, 2000 |
| Descrizione fisica | XVII, 331 p. : ill. ; 27 cm. |
| Disciplina | 615.3 |
| Soggetto topico | Biotecnologia - Impiego in farmacologia |
| ISBN | 88-08-09419-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Titolo uniforme | |
| Record Nr. | UNISA-990000324250203316 |
| Bologna : Zanichelli, 2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Carbohydrate-based drug discovery [[electronic resource] /] / Chi-Huey Wong (ed.)
| Carbohydrate-based drug discovery [[electronic resource] /] / Chi-Huey Wong (ed.) |
| Pubbl/distr/stampa | Weinheim ; ; [New York], : Wiley-VCH, c2003 |
| Descrizione fisica | 1 online resource (981 p.) |
| Disciplina |
615.3
615.7 |
| Altri autori (Persone) | WongChi-Huey |
| Soggetto topico |
Carbohydrate drugs
Carbohydrates - Synthesis Glycoconjugates - Physiological effect |
| ISBN |
1-280-52072-8
9786610520725 3-527-60578-9 3-527-60243-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Carbohydrate-based Drug Discovery; Contents; Preface; List of Contributors; Volume 1; 1 Synthetic Methodologies; 1.1 Introduction; 1.2 Tactical Analysis for Overall Synthetic Efficiency; 1.3 Methodological Improvements; 1.3.1 Chemistry; 1.3.2 Protecting Group Manipulations; 1.3.3 Modulation of the Reactivity of Glycosyl Donors; 1.3.4 Block Synthesis; 1.4 Accessibility; 1.4.1 Solution-based Chemistry; 1.4.2 One-Pot Glycosylation; 1.4.3 Solid-Phase Chemistry; 1.4.3.1 Fundamentals of Solid-Phase Oligosaccharide Synthesis; 1.4.3.2 The Support; 1.4.3.3 Linkers to the Support
1.4.3.4 Protecting Groups used in Solid-Phase Oligosaccharide Synthesis1.4.3.5 Solid-Phase Oligosaccharide Synthesis; 1.4.3.6 Monitoring of Reaction Progress; 1.4.4 Automation; 1.5 Concluding Remarks; 1.6 References; 2 Complex Carbohydrate Synthesis; 2.1 Introduction; 2.2 Synthetic Gangliosides; 2.2.1 Gangliosides GM4 and GM3, and their Analogues and Derivatives; 2.2.2 Sialylparagloboside (SPG) Analogues and Derivatives; 2.2.3 Selectin Ligands; 2.2.3.1 Sialyl Lewis x; 2.2.3.2 Novel 6-Sulfo sLe(x) Variants; 2.2.4 Siglec Ligands; 2.2.4.1 Chol-1 (α-Series) Gangliosides 2.2.4.2 Novel Sulfated Gangliosides2.3 Toxin Receptor; 2.4 Summary and Perspectives; 2.5 References; 3 The Chemistry of Sialic Acid; 3.1 Introduction; 3.2 Chemical and Enzymatic Synthesis of Sialic Acids; 3.3 Chemical Glycosidation of Sialic Acids; 3.3.1 Direct Chemical Sialylations; 3.3.1.1 2-Chloro Derivatives as Glycosyl Donors; 3.3.1.2 2-Thio Derivatives as Glycosyl Donors; 3.3.1.3 2-Xanthates as Glycosyl Donors; 3.3.1.3 2-Phosphites as Glycosyl Donors; 3.3.1.4 Miscellaneous Direct Chemical Methods; 3.3.2 Indirect Chemical Methods with the Use of a Participating Auxiliary at C-3 4.3.2 Immobilization of the Glycosyl Donor4.3.3 Bi-directional Strategy; 4.4 Support Materials; 4.4.1 Insoluble Supports; 4.4.2 Soluble Supports; 4.5 Linkers; 4.5.1 Silyl Ethers; 4.5.2 Acid- and Base-Labile Linkers; 4.5.3 Thioglycoside Linkers; 4.5.4 Linkers Cleaved by Oxidation; 4.5.5 Photocleavable Linkers; 4.5.6 Linkers Cleaved by Olefin Metathesis; 4.6 Synthesis of Oligosaccharides on Solid Support by Use of Different Glycosylating Agents; 4.6.1 1,2-Anhydrosugars - The Glycal Assembly Approach; 4.6.2 Glycosyl Sulfoxides; 4.6.3 Glycosyl Trichloroacetimidates; 4.6.4 Thioglycosides 4.6.5 Glycosyl Fluorides |
| Record Nr. | UNINA-9910146238303321 |
| Weinheim ; ; [New York], : Wiley-VCH, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Carbohydrates as Drugs [[electronic resource] /] / edited by Peter H. Seeberger, Christoph Rademacher
| Carbohydrates as Drugs [[electronic resource] /] / edited by Peter H. Seeberger, Christoph Rademacher |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (242 p.) |
| Disciplina | 615.3 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Carbohydrates Molecular biology Medicinal Chemistry Carbohydrate Chemistry Molecular Medicine |
| ISBN | 3-319-08675-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Carbohydrate-Based Synthetic Chemistry in the Context of Drug Design -- Iminosugars: Therapeutic Applications and Synthetic Considerations -- Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs -- Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapagliflozin for the Treatment of Type 2 Diabetes -- Design, Synthesis, and Applications of Galectin Modulators in Human Health -- Discovery and Application of FimH Antagonists -- Carbohydrate-Based Anti-Virulence Compounds Against Chronic Pseudomonas aeruginosa Infections with a Focus on Small Molecules -- The Evolution of a Glycoconjugate Vaccine for Candida albicans. |
| Record Nr. | UNINA-9910298645503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Challenge of CMC Regulatory Compliance for Biopharmaceuticals [[electronic resource] /] / by John Geigert
| The Challenge of CMC Regulatory Compliance for Biopharmaceuticals [[electronic resource] /] / by John Geigert |
| Autore | Geigert John |
| Edizione | [2nd ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (362 p.) |
| Disciplina |
610
615.15 615.19 615.3 |
| Soggetto topico |
Pharmaceutical technology
Medicine Pharmaceutical Sciences/Technology Biomedicine, general |
| ISBN | 1-4614-6916-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Complexity of Biologica CMC Regulation -- Biologics are Not Chemical Drugs -- An Effective CMC Strategy is Possible -- Challenge of Adventitious Agent Control -- Source Materials for Biologics -- Manufacture of the Biologic API -- The Biologic Final Product Process -- Complex Process-Related Impurities -- Molecular Structural Analysis -- Functional Activity (Potency) -- Setting Specifications and Expiry Dates -- Demonstrating Product Comparability -- CMC-Focused Regulatory Meetings -- References. |
| Record Nr. | UNINA-9910437854103321 |
Geigert John
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| New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical biology of natural products / David J. Newman, Gordon M. Cragg, and Paul G. Grothaus (edited by)
| Chemical biology of natural products / David J. Newman, Gordon M. Cragg, and Paul G. Grothaus (edited by) |
| Pubbl/distr/stampa | Boca Raton, : CRC Press, 2022 |
| Descrizione fisica | 622 p. : ill. ; 24 cm |
| Disciplina | 615.3 |
| Soggetto non controllato | farmacognosia |
| ISBN | 9781439841938 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910633700803321 |
| Boca Raton, : CRC Press, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational approaches in discovery & design of antimicrobial peptides / / edited by Agostinho Agüero-Chapin, Guillermin Agüero-Chapin, Yovani Marrero-Ponce
| Computational approaches in discovery & design of antimicrobial peptides / / edited by Agostinho Agüero-Chapin, Guillermin Agüero-Chapin, Yovani Marrero-Ponce |
| Pubbl/distr/stampa | [Place of publication not identified] : , : Multidisciplinary Digital Publishing Institute, , 2023 |
| Descrizione fisica | 1 online resource (258 pages) |
| Disciplina | 615.3 |
| Soggetto topico | Microbial peptides |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910734364603321 |
| [Place of publication not identified] : , : Multidisciplinary Digital Publishing Institute, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Understanding and Treatment of Gliomas [[electronic resource] /] / edited by Jeffrey Raizer, Andrew Parsa
| Current Understanding and Treatment of Gliomas [[electronic resource] /] / edited by Jeffrey Raizer, Andrew Parsa |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (186 p.) |
| Disciplina |
615.3
615.37 |
| Collana | Cancer Treatment and Research |
| Soggetto topico |
Oncology
Neurology Radiotherapy Oncology Neurology |
| ISBN | 3-319-12048-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Epidemiology of gliomas -- Glioma Biology and molecular markers -- Surgery for gliomas -- Radiation for gliomas -- Current treatment of low grade gliomas -- Current treatment of AG -- Current treatment of GBM -- Novel Chemotherapy approaches in gliomas -- Vaccine and Immunotherapy approaches -- Malignant gliomas in elderly -- Palliative care for glioma patients. |
| Record Nr. | UNINA-9910300199703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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