Alpha-Adrenoceptors: Molecular Biology, Biochemistry and Pharmacology / / editor, R.R. Ruffolo Jr
| Alpha-Adrenoceptors: Molecular Biology, Biochemistry and Pharmacology / / editor, R.R. Ruffolo Jr |
| Autore | Ruffolo Jr R.R |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1991 |
| Descrizione fisica | 1 online resource (XIV + 226 pages) : : 16 figures, 16 tables |
| Disciplina | 615/.7 |
| Altri autori (Persone) | RuffoloRobert R |
| Collana | Progress in Basic and Clinical Pharmacology |
| Soggetto topico |
Pharmacology
Biochemistry Molecular Biology Cardiovascular System Cell Biology Pharmacokinetics Physiology |
| ISBN |
9783318040890
3318040894 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 978-3-8055-5390-2_Cover -- 978-3-8055-5390-2_00I -- 978-3-8055-5390-2_001 -- 978-3-8055-5390-2_024 -- 978-3-8055-5390-2_044 -- 978-3-8055-5390-2_075 -- 978-3-8055-5390-2_115 -- 978-3-8055-5390-2_180 -- 978-3-8055-5390-2_221. |
| Altri titoli varianti | Alpha-Adrenoceptors |
| Record Nr. | UNINA-9910158702803321 |
Ruffolo Jr R.R
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| Basel : , : S. Karger, , 1991 | ||
| Lo trovi qui: Univ. Federico II | ||
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Basic pharmacokinetics / / Mohsen A. Hedaya
| Basic pharmacokinetics / / Mohsen A. Hedaya |
| Autore | Hedaya Mohsen A. |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , 2012 |
| Descrizione fisica | 1 online resource (581 p.) |
| Disciplina | 615/.7 |
| Collana | CRC Press Pharmacy Education Series |
| Soggetto topico | Pharmacokinetics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-429-25125-4
1-4398-5075-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Contents; Preface; Author; Chapter 1: Introduction to Pharmacokinetics; Chapter 2: Review of Mathematical Fundamentals; Chapter 3: Drug Pharmacokinetics Following a Single IV Bolus Administration: Drug Distribution; Chapter 4: Drug Pharmacokinetics Following a Single IV Bolus Administration: Drug Clearance; Chapter 5: Drug Pharmacokinetics Following a Single IV Bolus Administration: The Rate of Drug Elimination; Chapter 6: Drug Absorption Following Extravascular Administration: Biological, Physiological, and Pathological Considerations
Chapter 7: Drug Absorption Following Extravascular Administration: Molecular and Physicochemical ConsiderationsChapter 8: Drug Absorption Following Extravascular Administration: Formulation Factors; Chapter 9: Drug Pharmacokinetics Following Single Oral Drug Administration: The Rate of Drug Absorption; Chapter 10: Drug Pharmacokinetics Following Single Oral Drug Administration: The Extent of Drug Absorption; Chapter 11: Bioequivalence; Chapter 12: Drug Pharmacokinetics during Constant Rate IV Infusion: The Steady-State Principle; Chapter 13: Steady State during Multiple Drug Administration Chapter 14: Renal Drug ExcretionChapter 15: Metabolite Pharmacokinetics; Chapter 16: Nonlinear Pharmacokinetics; Chapter 17: Multicompartment Pharmacokinetic Models; Chapter 18: Drug Pharmacokinetics Following Administration by Intermittent Intravenous Infusion; Chapter 19: Pharmacokinetic-Pharmacodynamic Modeling; Chapter 20: Noncompartmental Approach in Pharmacokinetic Data Analysis; Chapter 21: Physiological Approach to Hepatic Clearance; Chapter 22: Physiologically Based Pharmacokinetic Models; Chapter 23: Therapeutic Drug Monitoring Chapter 24: Pharmacokinetics in Special Patient PopulationsChapter 25: Pharmacokinetic Drug-Drug Interactions; Chapter 26: Pharmacogenetics: The Genetic Basis of Pharmacokinetic and Pharmacodynamic Variability; Chapter 27: Applications of Computers in Pharmacokinetics; Chapter 28: The Companion CD; Solutions for the Practice Problems; Back Cover |
| Record Nr. | UNINA-9910460567003321 |
Hedaya Mohsen A.
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| Boca Raton : , : CRC Press, , 2012 | ||
| Lo trovi qui: Univ. Federico II | ||
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Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / / edited by Sara E. Rosenbaum
| Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / / edited by Sara E. Rosenbaum |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Incorporated, , [2017] |
| Descrizione fisica | 1 online resource (XIII, 552 pag.) : ill |
| Disciplina | 615/.7 |
| Soggetto topico |
Pharmacokinetics
Computer simulation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-119-14318-7
1-119-14316-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to pharmacokinetics and pharmacodynamics -- Passage of drugs through membranes -- Drug administration and drug absorption / Steven Sutton -- Drug distribution -- Drug elimination and clearance -- Compartmental models in pharmacokinetics -- Pharmacokinetics of an intravenous bolus injection in a one-compartment model -- Pharmacokinetics of an intravenous bolus injection in a two-compartment model -- Pharmacokinetics of extravascular drug administration / Steven Sutton -- Introduction to noncompartmental analysis -- Pharmacokinetics of intravenous infusion in a one-compartment model -- Multiple intravenous bolus injections in the one-compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacogenetics -- Models used to predict drug-drug interactions for orally administered drugs -- Introduction to physiologically based pharmacokinetic modeling -- Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson -- Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson. |
| Record Nr. | UNINA-9910153205803321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Incorporated, , [2017] | ||
| Lo trovi qui: Univ. Federico II | ||
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Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / / edited by Sara E. Rosenbaum
| Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / / edited by Sara E. Rosenbaum |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Incorporated, , [2017] |
| Descrizione fisica | 1 online resource (757 pages) : illustrations |
| Disciplina | 615/.7 |
| Soggetto topico |
Computer simulation
Pharmacokinetics |
| ISBN |
9781119143185
1119143187 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to pharmacokinetics and pharmacodynamics -- Passage of drugs through membranes -- Drug administration and drug absorption / Steven Sutton -- Drug distribution -- Drug elimination and clearance -- Compartmental models in pharmacokinetics -- Pharmacokinetics of an intravenous bolus injection in a one-compartment model -- Pharmacokinetics of an intravenous bolus injection in a two-compartment model -- Pharmacokinetics of extravascular drug administration / Steven Sutton -- Introduction to noncompartmental analysis -- Pharmacokinetics of intravenous infusion in a one-compartment model -- Multiple intravenous bolus injections in the one-compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacogenetics -- Models used to predict drug-drug interactions for orally administered drugs -- Introduction to physiologically based pharmacokinetic modeling -- Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson -- Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson. |
| Record Nr. | UNINA-9910795820203321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Incorporated, , [2017] | ||
| Lo trovi qui: Univ. Federico II | ||
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Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / / edited by Sara E. Rosenbaum
| Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / / edited by Sara E. Rosenbaum |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Incorporated, , [2017] |
| Descrizione fisica | 1 online resource (757 pages) : illustrations |
| Disciplina | 615/.7 |
| Soggetto topico |
Computer simulation
Pharmacokinetics |
| ISBN |
9781119143185
1119143187 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to pharmacokinetics and pharmacodynamics -- Passage of drugs through membranes -- Drug administration and drug absorption / Steven Sutton -- Drug distribution -- Drug elimination and clearance -- Compartmental models in pharmacokinetics -- Pharmacokinetics of an intravenous bolus injection in a one-compartment model -- Pharmacokinetics of an intravenous bolus injection in a two-compartment model -- Pharmacokinetics of extravascular drug administration / Steven Sutton -- Introduction to noncompartmental analysis -- Pharmacokinetics of intravenous infusion in a one-compartment model -- Multiple intravenous bolus injections in the one-compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacogenetics -- Models used to predict drug-drug interactions for orally administered drugs -- Introduction to physiologically based pharmacokinetic modeling -- Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson -- Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson. |
| Record Nr. | UNINA-9910813997903321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Incorporated, , [2017] | ||
| Lo trovi qui: Univ. Federico II | ||
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Biopharmaceuticals [[electronic resource] /] / S.N. Jogdand
| Biopharmaceuticals [[electronic resource] /] / S.N. Jogdand |
| Autore | Jogdand S. N |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Mumbai [India], : Himalaya Pub. House, 2006 |
| Descrizione fisica | 1 online resource (283 p.) |
| Disciplina | 615/.7 |
| Soggetto topico | Biopharmaceutics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-80173-2
9786612801730 1-4416-6139-5 93-5043-529-2 600-00-2715-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | COVER; CONTENTS; INTRODUCTION; MARKET FOR BIOPHARMACEUTICALS; BIOPHARMACEUTICAL INDUSTRY; BIOPHARMACEUTICAL SECTOR IN INDIA; DRUG DISCOVERY AND DRUG DESIGNING; PHARMACOKINETICS; CLINICAL TRIALS; REGULATORY; THERAPEUTIC PROTEINS; BLOOD PRODUCTS; MONOCLONAL ANTIBODIES; HORMONE THERAPY; VACCINE PRODUCTION-NEW DEVELOPMENTS; TRANSGENIC PRODUCTION OF BIOPHARMACEUTICALS; HUMAN GENE THERAPY; ANTISENSE TECHNOLOGY (DNA MEDICINES) |
| Record Nr. | UNINA-9910458795603321 |
Jogdand S. N
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| Mumbai [India], : Himalaya Pub. House, 2006 | ||
| Lo trovi qui: Univ. Federico II | ||
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Biopharmaceuticals [[electronic resource] /] / S.N. Jogdand
| Biopharmaceuticals [[electronic resource] /] / S.N. Jogdand |
| Autore | Jogdand S. N |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Mumbai [India], : Himalaya Pub. House, 2006 |
| Descrizione fisica | 1 online resource (283 p.) |
| Disciplina | 615/.7 |
| Soggetto topico | Biopharmaceutics |
| ISBN |
1-282-80173-2
9786612801730 1-4416-6139-5 93-5043-529-2 600-00-2715-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | COVER; CONTENTS; INTRODUCTION; MARKET FOR BIOPHARMACEUTICALS; BIOPHARMACEUTICAL INDUSTRY; BIOPHARMACEUTICAL SECTOR IN INDIA; DRUG DISCOVERY AND DRUG DESIGNING; PHARMACOKINETICS; CLINICAL TRIALS; REGULATORY; THERAPEUTIC PROTEINS; BLOOD PRODUCTS; MONOCLONAL ANTIBODIES; HORMONE THERAPY; VACCINE PRODUCTION-NEW DEVELOPMENTS; TRANSGENIC PRODUCTION OF BIOPHARMACEUTICALS; HUMAN GENE THERAPY; ANTISENSE TECHNOLOGY (DNA MEDICINES) |
| Record Nr. | UNINA-9910785115503321 |
Jogdand S. N
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| Mumbai [India], : Himalaya Pub. House, 2006 | ||
| Lo trovi qui: Univ. Federico II | ||
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Carbohydrate-based drug discovery / / Chi-Huey Wong (ed.)
| Carbohydrate-based drug discovery / / Chi-Huey Wong (ed.) |
| Pubbl/distr/stampa | Weinheim ; ; [New York], : Wiley-VCH, c2003 |
| Descrizione fisica | 1 online resource (981 p.) |
| Disciplina | 615/.7 |
| Altri autori (Persone) | WongChi-Huey |
| Soggetto topico |
Carbohydrate drugs
Carbohydrates - Synthesis Glycoconjugates - Physiological effect |
| ISBN |
9786610520725
9781280520723 1280520728 9783527605781 3527605789 9783527602438 3527602437 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Carbohydrate-based Drug Discovery; Contents; Preface; List of Contributors; Volume 1; 1 Synthetic Methodologies; 1.1 Introduction; 1.2 Tactical Analysis for Overall Synthetic Efficiency; 1.3 Methodological Improvements; 1.3.1 Chemistry; 1.3.2 Protecting Group Manipulations; 1.3.3 Modulation of the Reactivity of Glycosyl Donors; 1.3.4 Block Synthesis; 1.4 Accessibility; 1.4.1 Solution-based Chemistry; 1.4.2 One-Pot Glycosylation; 1.4.3 Solid-Phase Chemistry; 1.4.3.1 Fundamentals of Solid-Phase Oligosaccharide Synthesis; 1.4.3.2 The Support; 1.4.3.3 Linkers to the Support
1.4.3.4 Protecting Groups used in Solid-Phase Oligosaccharide Synthesis1.4.3.5 Solid-Phase Oligosaccharide Synthesis; 1.4.3.6 Monitoring of Reaction Progress; 1.4.4 Automation; 1.5 Concluding Remarks; 1.6 References; 2 Complex Carbohydrate Synthesis; 2.1 Introduction; 2.2 Synthetic Gangliosides; 2.2.1 Gangliosides GM4 and GM3, and their Analogues and Derivatives; 2.2.2 Sialylparagloboside (SPG) Analogues and Derivatives; 2.2.3 Selectin Ligands; 2.2.3.1 Sialyl Lewis x; 2.2.3.2 Novel 6-Sulfo sLe(x) Variants; 2.2.4 Siglec Ligands; 2.2.4.1 Chol-1 (α-Series) Gangliosides 2.2.4.2 Novel Sulfated Gangliosides2.3 Toxin Receptor; 2.4 Summary and Perspectives; 2.5 References; 3 The Chemistry of Sialic Acid; 3.1 Introduction; 3.2 Chemical and Enzymatic Synthesis of Sialic Acids; 3.3 Chemical Glycosidation of Sialic Acids; 3.3.1 Direct Chemical Sialylations; 3.3.1.1 2-Chloro Derivatives as Glycosyl Donors; 3.3.1.2 2-Thio Derivatives as Glycosyl Donors; 3.3.1.3 2-Xanthates as Glycosyl Donors; 3.3.1.3 2-Phosphites as Glycosyl Donors; 3.3.1.4 Miscellaneous Direct Chemical Methods; 3.3.2 Indirect Chemical Methods with the Use of a Participating Auxiliary at C-3 4.3.2 Immobilization of the Glycosyl Donor4.3.3 Bi-directional Strategy; 4.4 Support Materials; 4.4.1 Insoluble Supports; 4.4.2 Soluble Supports; 4.5 Linkers; 4.5.1 Silyl Ethers; 4.5.2 Acid- and Base-Labile Linkers; 4.5.3 Thioglycoside Linkers; 4.5.4 Linkers Cleaved by Oxidation; 4.5.5 Photocleavable Linkers; 4.5.6 Linkers Cleaved by Olefin Metathesis; 4.6 Synthesis of Oligosaccharides on Solid Support by Use of Different Glycosylating Agents; 4.6.1 1,2-Anhydrosugars - The Glycal Assembly Approach; 4.6.2 Glycosyl Sulfoxides; 4.6.3 Glycosyl Trichloroacetimidates; 4.6.4 Thioglycosides 4.6.5 Glycosyl Fluorides |
| Record Nr. | UNINA-9911019439603321 |
| Weinheim ; ; [New York], : Wiley-VCH, c2003 | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical applications of TGF-[beta]
| Clinical applications of TGF-[beta] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1991 |
| Descrizione fisica | 1 online resource (266 p.) |
| Disciplina | 615/.7 |
| Altri autori (Persone) |
BockGregory
MarshJoan |
| Collana | Ciba Foundation symposium |
| Soggetto topico | Transforming growth factors-beta - Therapeutic use |
| ISBN |
9786612347702
9781282347700 1282347705 9780470514061 047051406X 9780470514078 0470514078 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CLINICAL APPLICATIONS OF TGF-B; Contents; Introduction; Multiple forms of TGF-B: distinct promoters and differential expression; TGF-B receptors; Mechanisms in TGF-B action; Regulation of epithelial proliferation by TGF-B; Latent forms of TGF-B: molecular structure and mechanisms of action; General discussion I : The role of TGF-B in the nervous system; TGF-B: a possible autocrine immune regulator; TGF-B and wound healing; General discussion II : A stimulatory effect of transforming growth factors on skin tumour devdopmcnt in vivo; The effects of TGF-B on bone
TGF-B1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cellsEffects of TGF-Bs in the liver : cell proliferation and fibrogenesis; Role of TGF-B1 in experimental glomerulonephritis; The role of TGF-B in pulmonary fibrosis; In vivo and in vitro effects of TGF-B1 on normal and neoplastic haemopoiesis; Expression of TGF-B2 in human glioblastoma : a role in resistance to immune rejection?; Index of contributors; Subject index |
| Record Nr. | UNINA-9911019210403321 |
| Chichester ; ; New York, : Wiley, 1991 | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical Pharmacokinetics of Sulfonamides and Their Metabolites : : An Encyclopedia / / T.B. Vree
| Clinical Pharmacokinetics of Sulfonamides and Their Metabolites : : An Encyclopedia / / T.B. Vree |
| Autore | Vree T.B |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1987 |
| Descrizione fisica | 1 online resource (VIII + 216 pages) : : 100 figures, 83 tables |
| Disciplina |
615/.58 s
615/.7 |
| Altri autori (Persone) | HeksterYechiel Aaron <1947-> |
| Collana | Issn Series |
| Soggetto topico |
Pharmacology
Chemistry for Physicians Infectious Diseases Metabolism Pharmacokinetics Urology |
| ISBN |
9783318032123
3318032123 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 978-3-8055-4511-2_Cover -- 978-3-8055-4511-2_00I -- 978-3-8055-4511-2_001 -- 978-3-8055-4511-2_010 -- 978-3-8055-4511-2_012 -- 978-3-8055-4511-2_014 -- 978-3-8055-4511-2_016 -- 978-3-8055-4511-2_025 -- 978-3-8055-4511-2_031 -- 978-3-8055-4511-2_042 -- 978-3-8055-4511-2_049 -- 978-3-8055-4511-2_055 -- 978-3-8055-4511-2_057 -- 978-3-8055-4511-2_059 -- 978-3-8055-4511-2_066 -- 978-3-8055-4511-2_068 -- 978-3-8055-4511-2_069 -- 978-3-8055-4511-2_071 -- 978-3-8055-4511-2_076 -- 978-3-8055-4511-2_081 -- 978-3-8055-4511-2_088 -- 978-3-8055-4511-2_095 -- 978-3-8055-4511-2_100 -- 978-3-8055-4511-2_114 -- 978-3-8055-4511-2_118 -- 978-3-8055-4511-2_121 -- 978-3-8055-4511-2_123 -- 978-3-8055-4511-2_131 -- 978-3-8055-4511-2_134 -- 978-3-8055-4511-2_139 -- 978-3-8055-4511-2_143 -- 978-3-8055-4511-2_146 -- 978-3-8055-4511-2_153 -- 978-3-8055-4511-2_155 -- 978-3-8055-4511-2_157 -- 978-3-8055-4511-2_160 -- 978-3-8055-4511-2_167 -- 978-3-8055-4511-2_173 -- 978-3-8055-4511-2_177. |
| Record Nr. | UNINA-9910156327203321 |
Vree T.B
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| Basel : , : S. Karger, , 1987 | ||
| Lo trovi qui: Univ. Federico II | ||
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