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A means to an end : the biological basis of aging and death / William R. Clark
| A means to an end : the biological basis of aging and death / William R. Clark |
| Autore | CLARK, William R. |
| Pubbl/distr/stampa | New York ; Oxford [etc.] : Oxford University Press, 1999 |
| Descrizione fisica | XV, 234 p. : ill. ; 23 cm |
| Disciplina | 612.67 |
| Soggetto topico |
Longevità
Senescenza |
| ISBN | 0-19-515375-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996287638403316 |
CLARK, William R.
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| New York ; Oxford [etc.] : Oxford University Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Adult Vaccinations : Changing the Immunization Paradigm / / edited by Jean-Pierre Michel, Stefania Maggi
| Adult Vaccinations : Changing the Immunization Paradigm / / edited by Jean-Pierre Michel, Stefania Maggi |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (VIII, 127 p. 1 illus. in color.) |
| Disciplina |
618.97
612.67 614.47 |
| Collana | Practical Issues in Geriatrics |
| Soggetto topico |
Geriatrics
Infectious diseases Neurology Geriatrics/Gerontology Infectious Diseases Neurology |
| ISBN | 3-030-05159-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Foreword. Adult vaccinations: essential but too often forgotten -- 1. Complexity of vaccine manufacture and supply -- 2.Administration of vaccines: current process, new technologies, adjuvants -- 3.How can the European Medicines Agency support an appropriate strategy of adult vaccination? -- 4.Public health impact of adult vaccine-preventable diseases on performance, disability, mortality and health care costs in Europe -- 5.Outcomes after HPV vaccination -- 6.Impact of nutrition on adult vaccination efficacy -- 7.Profiling vaccines for an immunosenescent and multimorbid population -- 8.Comprehensive geriatric assessment in infectious diseases -- 9.Etiology of respiratory tract infections in adults in Europe: current knowledge and knowledge gaps -- 10.European flu vaccine regulations and their impacts in community-dwelling adults -- 11.Vaccination against pneumococcal disease in the European Union, with particular focus on Germany -- 12.Direct and indirect benefits of a comprehensive approach to vaccinating adults with influenza and pneumococcal vaccines, especially in patients with chronic diseases -- 13.Vaccination of health care professionals and protection of hospitalized adults and nursing home residents -- 14.Ongoing threats for older Europeans: Diphtheria, Pertussis and Tetanus -- 15.Herpes Zoster vaccination: a vaccine to prevent pain -- 16.Gastroenteritis burden in the adult community: prospects for vaccines -- 17. Travel vaccination -- 18. Integrating the veterinarian scientist to the one-health concept -- 19.Stressing the importance of adult immunization: suggestions for how to change the paradigm -- 20.How can we integrate life course vaccination into the new WHO definition of “Healthy Ageing”?. |
| Record Nr. | UNINA-9910337524103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in precision nutrition, personalization and health aging / / Alexander G. Haslberger
| Advances in precision nutrition, personalization and health aging / / Alexander G. Haslberger |
| Autore | Haslberger Alexander G. |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (302 pages) |
| Disciplina | 612.67 |
| Soggetto topico |
Aging - Nutritional aspects
Older people - Nutrition Nutrició Vellesa Persones grans |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9783031101533
9783031101526 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Reference -- Contents -- 1 Trends in Personalised Precision Nutrition, Objectives -- 1.1 The Rise of Molecular Nutrition -- 1.2 The Way to Personalisation -- 1.3 Consequences of Personalisation -- References -- 2 Individualization, Precision Nutrition Developments for the 21st Century -- 2.1 Introduction -- 2.2 Evolution of Nutrition Science in the 20th Century Toward Personalization -- 2.2.1 Nutrition in the Post-genomic Era -- 2.2.2 New Horizons in Personalized Nutrition -- 2.3 Individualization and Food Choices Based on Personalized/Precision Nutrition and Involvement of Diet in Chronic Diseases -- 2.4 Translating Personalized Nutrition for Society -- 2.4.1 Social Impact Regarding PN -- 2.4.2 PN-Associated Business and Value Creation Models -- 2.4.3 Social Concerns and Their Impact on PN Development -- 2.4.4 Consumer Attitudes Toward Personalized Nutrition -- 2.5 Future Outlook -- 2.6 Concluding Remarks -- 2.7 Financial Support -- References -- 3 Precision Nutrition from the View of Genetics and Epigenetics -- 3.1 Introduction -- 3.2 Nutrigenetics and Nutrigenomics -- 3.3 Epigenetic Mechanisms -- 3.4 The DOHaD Theory: The Importance of the Maternal Diet in Animal and Human Models -- 3.5 Epigenetic Mechanisms and Nutrients -- 3.6 Epigenetic Mechanisms of Antioxidants -- 3.7 Aging, Epigenetics, Nutrition -- 3.8 The Importance of the Gender in Precision Nutrition Medicine -- 3.9 Concluding Remarks -- References -- 4 Precision Nutrition from the View of the Gut Microbiome -- 4.1 Introduction -- 4.2 The Human Gut Microbiome-(Un)limited Possibilities for Improving Human Health -- 4.3 Exploring the Human Gut Microbiome: Start Low Go Slow-Advances in Microbiome Research -- 4.3.1 Eubiosis versus Dysbiosis -- 4.4 The Microbiome Study in PN Research-Important Aspects (see Figs. 4.3 and 4.4, Box 2).
4.4.1 Setting Standards in the Microbiome Field -- 4.4.2 Visualizing Methods in Microbiome Research -- 4.5 From the Clinical Trial to the Personal Recommendation: Putting the Individual Pieces of the Puzzle Together -- 4.6 Conclusion -- References -- 5 Personalized Nutrition for Healthy Aging, A Review -- 5.1 Healthy Aging -- 5.1.1 Genetics and Healthy Aging -- 5.1.2 Epigenetics and Healthy Aging -- 5.1.3 Histones and Healthy Aging -- 5.1.4 Noncoding RNAs (NcRNAs) and Aging -- 5.1.5 Aging of the Immune System (I.S.) and Epigenetics -- 5.1.6 Neurodegenerative Diseases, Aging, and Epigenetics -- 5.1.7 Microbiota and Healthy Aging -- 5.1.8 Individual-Specific Aging -- 5.2 Ways to Personalization -- 5.2.1 Missing Heritability -- 5.2.2 Markers Enable a Personalized Pre- and Intervention -- 5.3 Developments of Precision Medicine -- 5.4 Development of Personalized Precision Nutrition -- 5.4.1 Personalized Nutrition and Nutriepigenetics -- 5.4.2 Personalized Nutrition and Gene Expression -- 5.4.3 Personalized Nutrition and Microbiota-Epigenetic Interactions -- 5.5 Omics Approaches and Data Integration -- 5.5.1 Translation of Personalized Precision Nutrition into Praxis -- 5.5.2 Personalization or Stratification, Metabotypes -- 5.5.3 Personalized Precision Nutrition and Consumer Aspects -- 5.5.4 Consumer Supporting Organizations in Between Multiple Interests, Discussion -- References -- 6 Precise Nutrition and Metabolic Syndrome, Remodeling the Microbiome with Polyphenols, Probiotics, and Postbiotics -- 6.1 Introduction -- 6.2 Metabolic Syndrome-Definition, Prevalence, and Pathophysiology -- 6.3 The Microbiome-Composition, Establishment, and Functions -- 6.4 Role of Microbiome in Development of Metabolic Syndrome -- 6.5 Precision Nutrition-Gut Microbiota as a Target for Metabolic Syndrome Treatment -- 6.5.1 Probiotics -- 6.5.2 Postbiotics -- 6.5.3 Polyphenols. 6.6 Conclusion -- Literatures -- 7 Precision Nutrition and Metabolomics, a Model of Alzheimer's Disease -- 7.1 Introduction -- 7.2 Metabolomics and the -Omics Cascade -- 7.3 How Metabolomics Provides Actionable Insights into Disease Pathophysiology -- 7.4 Western-Style Diet, Metabolism, and the Epidemiology of Chronic Disease -- 7.5 Western-Style Diet, the Association with Intracellular Malnutrition, and Nutritional Interventions in Alzheimer's Disease -- 7.6 A Metabolic Model of Alzheimer's Disease, and Its Relationship with Nutritional and Microbiome-Related Factors -- 7.6.1 Lipid Metabolism -- 7.6.2 Glucose Homeostasis and Alterations in Energy Supply -- 7.6.3 Bile Acid Metabolism -- 7.6.4 The Metabolic Model of Alzheimer's Disease (AD) -- 7.7 Conclusion -- References -- 8 Precision Nutrition and Cognitive Decline -- 8.1 Introduction -- 8.2 Nutrients and Dietary Patterns -- 8.2.1 Antioxidants -- 8.2.2 Vitamins -- 8.2.3 Omega-3 Fatty Acids -- 8.2.4 Dietary Patterns -- 8.3 Individualized Response to Diet -- 8.3.1 Human Genome -- 8.3.2 Epigenome -- 8.3.3 Microbiome -- 8.4 Risk Factors for Dementia -- 8.5 Challenges and Future Directions -- References -- 9 Algorithms for and Challenges in the Analysis of Markers in Personalized Health Care -- 9.1 Introduction -- 9.2 Supervised Learning -- 9.2.1 Basic Definitions and the Learning Task -- 9.2.2 Loss Functions -- 9.2.3 Errors -- 9.2.4 Model Selection, Model Assessment, and Datasets -- 9.2.5 Learnability and Data -- 9.2.6 Bias and Variance -- 9.3 Algorithms -- 9.3.1 KNN -- 9.3.2 Linear Regression -- 9.3.3 Logistic Regression -- 9.3.4 Artificial Neural Networks -- 9.3.5 Naive Bayes Classifiers -- 9.3.6 Decision Trees and Random Forests -- 9.4 The Challenges -- 9.4.1 Overfitting -- 9.4.2 (Epi-)genetic Problems -- 9.4.3 A Numerical Example -- 9.5 Quality Metrics. 9.5.1 True and False Positives and Negatives -- 9.5.2 Positive and Negative Rates -- 9.5.3 Predictive Values Etc. -- 9.5.4 Prevalence, Accuracy, and Informedness -- 9.5.5 Weighted Informedness or Weighted Youden's Index -- 9.5.6 Confusion Matrix -- 9.5.7 A Numerical Example -- 9.6 Probably Approximately Correct -- 9.7 Conclusions -- 10 Precise Nutrition and Functional Foods -- 10.1 Novel Food, Food Supplements, Nutraceuticals, Phytoceuticals, Medicinal Foods -- 10.2 Fasting, Caloric Restriction (CR) -- 10.3 Modulating the Diet-Gut Microbiome Interplay -- 10.4 Probiotics -- 10.5 Prebiotics -- 10.6 Nutraceuticals -- 10.7 Medical Foods -- 10.8 Mechanistic Aspects of Special Foods -- 10.8.1 Epigenetic Active Foods -- 10.8.2 Sirtuin Activation by "Sirtfoods" -- 10.9 Senolytic Foods -- 10.9.1 Fasting Mimetics -- 10.10 Personalization, Discussion -- References -- 11 Precision Nutrition from a Practical Clinical View, Case Study -- 11.1 Introduction -- 11.2 Chances of Diagnostics and Markers -- 11.3 Case Study -- 11.4 Conclusion -- 12 Translational Aspects in Precision Nutrition, Personalization, Biomarkers and Healthy Aging -- 12.1 Boom in Medical Self-tests-Since Corona Pandemic -- 12.2 From One Fits-All Recommendations to Personalized Tests -- 12.3 Nutrigenetics -- 12.4 Impact of Genetic Lifestyle Tests -- 12.5 Compliance of Lifestyle Change -- 12.6 Nutrigeneomics -- 12.7 Personalized Epigenetic Testing -- 12.8 Personalized Microbiota Analysis -- 12.9 Legal Responsibility -- 12.10 Validation of Study Results and Generation of Limit Values -- 12.11 Conclusion -- Appendix -- References. |
| Record Nr. | UNINA-9910629286503321 |
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Haslberger Alexander G.
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| Cham, Switzerland : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Age
| Age |
| Pubbl/distr/stampa | Omaha, Neb., : American Aging Association, 1978-1999 |
| Disciplina | 612.67 |
| Soggetto topico |
Aging
Older people |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 2331-3765 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910332059403321 |
| Omaha, Neb., : American Aging Association, 1978-1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Age
| Age |
| Pubbl/distr/stampa | Omaha, Neb., : American Aging Association, 1978-1999 |
| Disciplina | 612.67 |
| Soggetto topico |
Aging
Older people |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 2331-3765 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996211100103316 |
| Omaha, Neb., : American Aging Association, 1978-1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Age as disease : anti-aging technologies, sites and practices / / David-Jack Fletcher
| Age as disease : anti-aging technologies, sites and practices / / David-Jack Fletcher |
| Autore | Fletcher David-Jack |
| Pubbl/distr/stampa | Singapore : , : Palgrave Macmillan, , [2021] |
| Descrizione fisica | 1 online resource (vii, 349 pages) |
| Disciplina | 612.67 |
| Soggetto topico |
Aging - Physiological aspects
Aging - Social aspects |
| Soggetto genere / forma | Electronic books. |
| ISBN | 981-16-0013-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Intro -- Acknowledgments -- Contents -- 1: Introduction -- What Is Aging? -- Foucauldian Biopolitics -- Neoliberalism -- Somatechnics -- Ethics -- Chapter Overview -- References -- 2: The Biopolitics of Somatechnologies and Diseased Bodies -- Biopolitics -- A Brief History of Longevity and Rejuvenation Techniques -- Algorithmic Somatechnologies: The 'Magic' of Trinfinity8 -- The American Dream, Eugenic Practices and the Nazi State -- Neo-eugenic Somatechnologies -- Governmentality and the Self -- Origins of the Camp -- References -- 3: Gerontological Hygiene: Emergence and Contemporary Practice -- Archaeology of Gerontology -- The Neoliberal Subject and Aging Policy -- 'Productive Aging' and Neoliberalism's 'Climate of Consent' -- Pathologizing Age: Biogerontology and Anti-Aging Somatechnologies -- Compounds for Elderly Citizens: Spaces for Abnormal and Docile Bodies -- The Surveillance of Aging -- Therapeutic Regimes: Creating Normative and Docile Bodies -- Implications for the Construction of the Human -- References -- 4: Questions of the 'Human' -- Genealogy of Humanism -- Inclusionary and Exclusionary Regimes -- Heidegger's Construction of the Human -- The Ethical Implications of Heideggerian Philosophy -- Arendt's Characteristics of the Human -- The Medicalized Elderly as Animal Laborans -- Derrida + The Human -- References -- 5: Gerontological Treatment Protocols: An Ethical Inquiry -- An Overview of Ethics -- The Animal Within: The Ethics of Testicular Xenotransplantation -- The Abolition of Aging: The GeroScience Network and Gerontological Hygiene -- References -- 6: Conclusion: Trajectories of Gerontological Hygiene -- Why Should Old Age Not Be Abolished? -- Emergent Technologies -- References -- References. |
| Record Nr. | UNINA-9910483381103321 |
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Fletcher David-Jack
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| Singapore : , : Palgrave Macmillan, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ageing Asia and the Pacific in changing times : implications for sustainable development / / edited by Subas Dhakal, Alan R. Nankervis, John Burgess
| Ageing Asia and the Pacific in changing times : implications for sustainable development / / edited by Subas Dhakal, Alan R. Nankervis, John Burgess |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (246 pages) |
| Disciplina | 612.67 |
| Soggetto topico |
Aging
Older people Sustainable development - Asia Envelliment de la població Envelliment Persones grans Desenvolupament sostenible |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
981-16-6662-8
981-16-6663-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910743357503321 |
| Singapore : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Ageing Immune System and Health / / edited by Valquiria Bueno, Janet M. Lord, Thomas A. Jackson
| The Ageing Immune System and Health / / edited by Valquiria Bueno, Janet M. Lord, Thomas A. Jackson |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XII, 182 p. 19 illus., 11 illus. in color.) |
| Disciplina |
618.97
612.67 |
| Soggetto topico |
Geriatrics
Aging Immunology Cell biology Geriatrics/Gerontology Cell Biology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Introduction -- 2. Innate Immune Response and Ageing (neutrophils, monocytes, dendritic cells, DAMPs, PAMPs -- 3. Adaptive Immune Response and Aging (T and B lymphocytes, naïve, effector and memory phenotypes and functions) -- 4. Modulatory/Suppressive Cells and Ageing (T regulatory cells, B regulatory cells, Myeloid Derived Suppressor Cells, Modulatory Neutrophils, M1 and M2 macrophages) -- 5. Mucosal Immune System and Ageing -- 6. Epigenetics and Ageing -- 7. Cancer and Ageing -- 8. Infections/Vaccination and Ageing -- 9. Cytomegalovirus and immmunosenescence -- 10. Frailty and Ageing -- 11. Inflammation and Neurodegenerative Diseases and Ageing -- 12. Effects of chronic inflammatory diseases (chronic kidney disease, rheumatoid arthritis, crohns disease etc) on the ageing of the immune system -- 13. Interventions in Elderly focusing Immunosenescence (physical activity, nutrition, supplements). |
| Record Nr. | UNINA-9910254477403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ageing in Times of the COVID-19 Pandemic [[electronic resource] /] / edited by Julia Simonson, Jenna Wünsche, Clemens Tesch-Römer
| Ageing in Times of the COVID-19 Pandemic [[electronic resource] /] / edited by Julia Simonson, Jenna Wünsche, Clemens Tesch-Römer |
| Autore | Simonson Julia |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Wiesbaden : , : Springer Fachmedien Wiesbaden : , : Imprint : Springer VS, , 2023 |
| Descrizione fisica | 1 online resource (250 pages) |
| Disciplina | 612.67 |
| Altri autori (Persone) |
WünscheJenna
Tesch-RömerClemens |
| Soggetto topico |
Sociology
Social groups Social medicine Gerontology Medicine, Preventive Health promotion Sociology of Family, Youth and Aging Health, Medicine and Society Medical Sociology Health Promotion and Disease Prevention |
| ISBN | 3-658-40487-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I: Introduction -- Part II: I Material and the employment issues during the Corona Pandemic -- Part III: Active ageing and participation issues during the Corona Pandemic -- Part IV: Health and well-being issues during the Corona Pandemic -- Part V: Social issues during the Corona Pandemic and beyond -- Part VI: Conclusion and implications. |
| Record Nr. | UNINA-9910729736703321 |
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Simonson Julia
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| Wiesbaden : , : Springer Fachmedien Wiesbaden : , : Imprint : Springer VS, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ageing in transient tissues [[electronic resource] /] / editors for the Ciba Foundation, G.E.W. Wolstenholme and Elaine C.P. Millar
| Ageing in transient tissues [[electronic resource] /] / editors for the Ciba Foundation, G.E.W. Wolstenholme and Elaine C.P. Millar |
| Autore | Symposium CIBA Foundation |
| Pubbl/distr/stampa | London, : J. & A. Churchill, 1956 |
| Descrizione fisica | 1 online resource (302 p.) |
| Disciplina | 612.67 |
| Altri autori (Persone) |
WolstenholmeG. E. W (Gordon Ethelbert Ward)
MillarElaine C. P |
| Collana | Ciba Foundation colloquia on ageing |
| Soggetto topico |
Aging
Animals - Growth Placenta Reproduction |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-76857-6
9786613679345 0-470-71898-6 0-470-71643-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CIBA FOUNDATION COLLOQUIA ON AGEING VOLUME 2; CONTENTS; Chairman's opening remarks; Organ culture studies of foetal rat reproductive tracts; Discussion; The age factor in some prenatal endocrine events; Discussion; The regenerative capacity of ovarian tissue; Discussion; The history and fate of redundant follicles; Discussion; The corpus luteum of the guinea pig; Discussion; Observations on the cytomorphosis of the germinal and interstitial cells of the human testis; Discussion; Mitochondrial changes in different physiological states; Discussion
Morphological aspects of ageing in the placentaDiscussion; Chronological changes in placental function; Discussion; Biochemical evidence of ageing in the placenta; Discussion; Uptake of radio-potassium (42K) by the uterus and placenta during the advancement of pregnancy in the rat and the goat; Discussion; Modifications in the foetal development of the rat after administration of growth hormone or cortisone to the mother; Discussion; The growth cycle of deer antlers; Discussion; Ageing of the axillary apocrine sweat glands in the human female; Discussion; The metabolism of senescent leaves DiscussionThe physical instability of human red blood cells and its possible importance in their senescence; Ageing in human red cells; Discussion; General Discussion |
| Record Nr. | UNINA-9910144700003321 |
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Symposium CIBA Foundation
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| London, : J. & A. Churchill, 1956 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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