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Blood Cells : A Practical Guide
| Blood Cells : A Practical Guide |
| Autore | Bain Barbara J |
| Edizione | [7th ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2025 |
| Descrizione fisica | 1 online resource (605 pages) |
| Disciplina | 612.1/1 |
| Altri autori (Persone) | LeachMike |
| Soggetto topico |
Blood cells
Blood cell count Blood - Analysis |
| ISBN |
1-394-33208-4
1-394-33207-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Acknowledgements -- List of abbreviations -- About the companion website -- CHAPTER 1 Blood sampling and blood film preparation and examination -- Obtaining a blood specimen -- Peripheral venous blood -- 'Capillary' blood -- Cord blood -- Fetal blood -- Blood specimens from other sites -- Anticoagulants and specimen containers -- Guidelines -- Needle-stick injury -- Specimen mixing -- Making a blood film -- Manual spreading of a blood film on a glass slide (wedge-spread film) -- Other methods of spreading thin films -- Thick films -- Unstained wet preparations -- Fixation, staining and mounting -- Fixation -- Staining -- Mounting -- Storage of slides -- Setting up and using a microscope -- Identifying the source of a problem and preventing problems -- Examining a blood film -- References -- CHAPTER 2 Performing a blood count -- Basic techniques -- Haemoglobin concentration -- Packed cell volume -- The red cell count -- Derived red cell variables - the red cell indices -- The white cell count -- The platelet count -- The differential white cell count -- The reticulocyte count -- Units and approved abbreviations -- Automated image analysis -- Pattern-recognition automated differential counters -- Automated blood cell counters -- Principles of operation of automated haematology counters -- Beckman Coulter instruments -- Sysmex and other instruments incorporating impedance measurements -- Siemens instruments (previously Technicon then Bayer instruments) -- Abbott Cell-Dyn and Alinity instruments -- HORIBA Medical -- Nihon Kohden instruments -- Mindray instruments -- Automated reticulocyte count and reticulated platelet count -- Selection of an automated instrument -- Near-patient/point-of-care testing -- Non-invasive methods -- Storage of blood specimens prior to testing -- References.
CHAPTER 3 Morphology of blood cells -- Examining the blood film -- Storage-induced and other artefacts -- Erythrocytes -- Anisocytosis -- Microcytosis -- Macrocytosis -- Hypochromia -- Hyperchromia -- Anisochromasia -- Dimorphism -- Polychromasia -- Poikilocytosis -- Inclusions in erythrocytes -- Circulating nucleated red blood cells -- Red cell agglutination, rouleaux formation and red cell rosetting -- Leucocytes -- Granulocytes -- The neutrophil -- The eosinophil -- The basophil -- Lymphocytes and plasma cells -- The lymphocyte -- The plasma cell -- Cells of monocyte lineage -- The monocyte -- Monocyte precursors -- The macrophage -- Granulocyte precursors -- The myeloblast -- The promyelocyte -- The myelocyte -- The metamyelocyte -- Leucoerythroblastic blood films -- The mast cell -- Disintegrated cells -- Necrotic bone marrow cells -- Platelets and circulating megakaryocytes -- Platelets -- Abnormalities of platelet size -- Other abnormalities of platelet morphology and distribution including platelet aggregation and satellism and phagocytosis of platelets -- Megakaryocytes -- Abnormal megakaryocytes and megakaryoblasts -- Blood film in healthy subjects -- Healthy adult -- Infancy and childhood -- Neonate -- Hyposplenism -- Non-haemopoietic cells -- Endothelial cells -- Epithelial cells -- Fat cells -- Mesothelial cells -- Amniotic fluid cells -- Non-haemopoietic malignant cells and mucin -- Micro-organisms in blood films -- Bacteria -- Fungi -- Parasites -- Malaria -- Babesiosis -- Toxoplasmosis -- Infection by haemoflagellates -- Filariasis -- Further learning resources -- References -- CHAPTER 4 Detecting erroneous blood counts -- The sources of errors in blood counts -- The detection of errors in automated blood counts -- Errors in automated white cell counts -- Errors in haemoglobin concentration and red cell indices. Haemoglobin concentration -- Red blood cell count, mean cell volume and haematocrit -- Mean cell haemoglobin, mean cell haemoglobin concentration and red cell distribution width -- Factitious erythroblastaemia -- Errors in platelet counts -- Errors in automated differential counts -- Five- to seven-part differential counts -- Errors in automated reticulocyte counts and other reticulocyte measurements -- References -- CHAPTER 5 Normal ranges -- Normal ranges for adults -- Normal ranges for neonates and fetuses -- Normal ranges in infants and children -- Normal ranges in pregnancy -- Normal ranges for platelet counts and other platelet variables -- Normal ranges for reticulocyte counts -- References -- CHAPTER 6 Quantitative changes in blood cells -- Polycythaemia -- Reticulocytosis -- Leucocytosis -- Neutrophil leucocytosis - neutrophilia -- Eosinophil leucocytosis - eosinophilia -- Basophil leucocytosis - basophilia -- Lymphocytosis -- Monocytosis -- Plasmacytosis -- Thrombocytosis -- Blood film and count -- Further tests -- Anaemia -- Blood film and count -- Further tests -- Reticulocytopenia -- Leucopenia -- Neutropenia -- Eosinopenia -- Basopenia -- Monocytopenia -- Lymphocytopenia (lymphopenia) -- Thrombocytopenia -- Blood film and count -- Other tests -- Pancytopenia -- Blood film and count -- Differential diagnosis -- Further tests -- References -- CHAPTER 7 Important supplementary tests -- Cytochemical techniques for investigation of erythrocyte disorders -- Heinz bodies -- Haemoglobin H inclusions -- Haemoglobin F-containing cells -- Perls reaction for iron -- Glucose-6-phosphate dehydrogenase -- Cytochemical stains used in the diagnosis and classification of leukaemias -- Neutrophil alkaline phosphatase -- Myeloperoxidase -- Sudan black B -- Naphthol AS-D chloroacetate esterase -- Non-specific esterases -- Combined esterase. Periodic acid-Schiff reaction -- Acid phosphatase -- Flow cytometric immunophenotyping -- Immunocytochemistry -- Cytogenetic analysis -- Fluorescence in situ hybridisation -- Molecular genetic analysis -- Ultrastructural examination -- References -- Further reading -- CHAPTER 8 Disorders of red cells and platelets -- Disorders of red cells -- Hypochromic and microcytic anaemias and thalassaemias -- Disorders resulting from a defect in haem synthesis -- Disorders resulting from a defect in globin chain synthesis -- Disorders resulting from a defect in globin chain synthesis -- Haemoglobinopathies -- Macrocytic anaemias -- Megaloblastic anaemia -- Macrocytic anaemia associated with excess alcohol intake and liver disease -- Macrocytic anaemia due to a myelodysplastic syndrome -- Other rare macrocytic anaemias -- Congenital haemolytic anaemias -- Hereditary spherocytosis and variants -- Hereditary elliptocytosis and ovalocytosis -- Hereditary pyropoikilocytosis -- Southeast Asian ovalocytosis -- Hereditary stomatocytosis and related conditions -- Other defects involving the erythrocyte membrane -- Red cell enzyme abnormalities -- Acquired haemolytic anaemias -- Acquired haemolytic anaemias with an immune mechanism -- Non-immune acquired haemolytic anaemias -- Miscellaneous causes of acquired haemolytic anaemia -- Haemolysis as a contributing factor to anaemia -- Dyserythropoietic anaemias -- Congenital dyserythropoietic anaemias -- Acquired dyserythropoietic anaemias -- Aplastic anaemia and red cell aplasia -- Aplastic anaemia -- Pure red cell aplasia -- Red cell effects of bacterial, viral and parasitic infections and vaccinations -- Bacterial infection -- Viral infection -- Parasitic infections -- Polycythaemia -- Relative polycythaemia -- True polycythaemia -- Disorders of platelets -- Thrombocytopenia. Autoimmune ('idiopathic') thrombocytopenic purpura (ITP) -- Thrombotic thrombocytopenic purpura -- Platelet effects of bacterial, viral and parasitic infections and vaccinations -- Infection- and vaccine-related thrombocytopenia and thrombocytosis -- Thrombocytosis -- Familial thrombocytosis -- Essential thrombocythaemia -- Leucoerythroblastic blood films -- Primary myelofibrosis -- References -- CHAPTER 9 Disorders of white cells -- Reactive changes in white cells -- Bacterial infection -- Viral infections -- Infectious mononucleosis -- Other reactive changes in leucocytes -- Vaccination effects on leucocytes -- Persistent polyclonal B-cell lymphocytosis -- Reactive eosinophilia -- T-cell-mediated hypereosinophilia -- Idiopathic hypereosinophilic syndrome -- Leukaemoid reactions -- Cytopenias -- Severe congenital neutropenia -- Cyclical neutropenia -- Autoimmune neutropenia -- Chronic idiopathic neutropenia -- Haematological neoplasms -- Acute myeloid leukaemia and related conditions -- The myelodysplastic neoplasms/syndromes -- Myeloproliferative and myelodysplastic/myeloproliferative neoplasms -- Myeloproliferative neoplasms -- Myelodysplastic/myeloproliferative neoplasms -- Acute lymphoblastic leukaemia/lymphoma -- Blood film and count -- Differential diagnosis -- Further tests -- Chronic lymphoid leukaemias and lymphomas -- B-lineage lymphoproliferative disorders -- T-lineage and NK-lineage lymphoproliferative disorders -- T-cell prolymphocytic leukaemia -- Hodgkin lymphoma -- References -- Further reading -- Index -- EULA. |
| Record Nr. | UNINA-9911019516303321 |
Bain Barbara J
|
||
| Newark : , : John Wiley & Sons, Incorporated, , 2025 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Blood cells [[electronic resource] ] : a practical guide / / Barbara J. Bain
| Blood cells [[electronic resource] ] : a practical guide / / Barbara J. Bain |
| Autore | Bain Barbara J |
| Edizione | [4th ed.] |
| Pubbl/distr/stampa | Malden, Mass ; ; Oxford, : Blackwell, 2006 |
| Descrizione fisica | 1 online resource (488 p.) |
| Disciplina |
612.1/1
612.11 |
| Soggetto topico |
Blood cells
Blood cell count |
| ISBN |
1-280-74880-X
1-78034-579-8 9786610748808 0-470-76420-1 0-470-98755-3 1-4051-7160-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Blood Cells A Practical Guide; Contents; Preface; Acknowledgements; List of abbreviations; 1. Blood sampling and blood film preparation and examination; 2. Performing a blood count; 3. Morphology of blood cells; 4. Detecting erroneous blood counts; 5. Normal ranges; 6. Quantitative changes in blood cells; 7. Important supplementary tests; 8. Disorders of red cells and platelets; 9. Disorders of white cells; Index |
| Record Nr. | UNISA-996213069603316 |
|
Bain Barbara J
|
||
| Malden, Mass ; ; Oxford, : Blackwell, 2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
The mechanics of the circulation / / C.G. Caro [and others] [[electronic resource]]
| The mechanics of the circulation / / C.G. Caro [and others] [[electronic resource]] |
| Autore | Caro Colin G (Colin Gerald) |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2012 |
| Descrizione fisica | 1 online resource (xxvi, 523 pages) : digital, PDF file(s) |
| Disciplina | 612.1/1 |
| Soggetto topico |
Hemodynamics
Blood - Circulation |
| ISBN |
1-107-22282-6
9786613728098 1-139-18735-X 1-280-88678-1 1-139-18272-2 1-139-18503-9 1-139-18863-1 1-139-01340-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Machine generated contents note: Preface to the second edition; Preface to the first edition; Part I. Background Mechanics: 1. Particles and continuous materials; 2. Particle mechanics; 3. Units; 4. Basic ideas in fluid mechanics; 5. Flow in pipes and around objects; 6. Dimensional analysis; 7. Solid mechanics and the properties of blood vessel walls; 8. Oscillations and waves; 9. An introduction to mass transfer; Part II. Mechanics of the Circulation: 10. Blood; 11. The heart; 12. The systemic arteries; 13. The systemic microcirculation; 14. The systemic veins; 15. The pulmonary circulation; Index. |
| Record Nr. | UNINA-9910461521703321 |
|
Caro Colin G (Colin Gerald)
|
||
| Cambridge : , : Cambridge University Press, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The mechanics of the circulation / / C.G. Caro [and others] [[electronic resource]]
| The mechanics of the circulation / / C.G. Caro [and others] [[electronic resource]] |
| Autore | Caro Colin G (Colin Gerald) |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2012 |
| Descrizione fisica | 1 online resource (xxvi, 523 pages) : digital, PDF file(s) |
| Disciplina | 612.1/1 |
| Altri autori (Persone) | CaroColin G (Colin Gerald) |
| Soggetto topico |
Hemodynamics
Blood - Circulation |
| ISBN |
1-107-22282-6
9786613728098 1-139-18735-X 1-280-88678-1 1-139-18272-2 1-139-18503-9 1-139-18863-1 1-139-01340-8 |
| Classificazione | MAT000000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Machine generated contents note: Preface to the second edition; Preface to the first edition; Part I. Background Mechanics: 1. Particles and continuous materials; 2. Particle mechanics; 3. Units; 4. Basic ideas in fluid mechanics; 5. Flow in pipes and around objects; 6. Dimensional analysis; 7. Solid mechanics and the properties of blood vessel walls; 8. Oscillations and waves; 9. An introduction to mass transfer; Part II. Mechanics of the Circulation: 10. Blood; 11. The heart; 12. The systemic arteries; 13. The systemic microcirculation; 14. The systemic veins; 15. The pulmonary circulation; Index. |
| Record Nr. | UNINA-9910790463003321 |
|
Caro Colin G (Colin Gerald)
|
||
| Cambridge : , : Cambridge University Press, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transcription factors [[electronic resource] ] : normal and malignant development of blood cells / / edited by Katya Ravid, Jonathan Licht
| Transcription factors [[electronic resource] ] : normal and malignant development of blood cells / / edited by Katya Ravid, Jonathan Licht |
| Pubbl/distr/stampa | New York, : Wiley-Liss, c2001 |
| Descrizione fisica | 1 online resource (642 p.) |
| Disciplina |
612.1/1
616.15 |
| Altri autori (Persone) |
RavidKatya
LichtJonathan D |
| Soggetto topico |
Hematopoiesis
Genetic regulation Leukemia - Genetic aspects Transcription factors Genetic transcription |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-36661-3
9786610366613 0-470-34865-8 0-471-46106-7 0-471-22388-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TRANSCRIPTION FACTORS; CONTENTS; Introduction; Contributors; I TRANSCRIPTION FACTORS AND THE MEGAKARYOCYTIC AND ERYTHROID LINEAGES; 1 The Role of GATA-1 and FOG in Erythroid and Megakaryocytic Differentiation; 2 Regulation of Megakaryocyte and Erythroid Differentiation by NF-E2; 3 Transcription Factors Involved in Lineage-Specific Gene Expression During Megakaryopoiesis; 4 Role of TAL1/SCL Transcription Factor in Normal and Leukemic Hematopoiesis; 5 EKLF and the Development of the Erythroid Lineage; II TRANSCRIPTION FACTORS AND THE MYELOID LINEAGE
6 RUNX1(AML1) and CBFB: Genes Required for the Development of All Definitive Hematopoietic Lineages7 PU.1 and the Development of the Myeloid Lineage; 8 CCAAT/Enhancer-Binding Proteins in Myeloid Cells; 9 Homeobox Gene Networks and the Regulation of Hematopoiesis; 10 The Role of Retinoic Acid Receptors in Myeloid Differentiation; 11 Transcriptional Targets of the Vitamin D(3) Receptor During Myeloid Cell Differentiation; III TRANSCRIPTION FACTORS AND THE LYMPHOID LINEAGE; 12 The Role of Ikaros Family Genes in Lymphopcyte Differentiation and Proliferation 13 The Role of PU.1 in B-Lymphocyte Development and Function14 The Role of Pax5 (BSAP) in Early and Late B-Cell Development; 15 Janus Kinases and STAT Family Transcription Factors: Their Role in the Function and Development of Lymphoid Cells; 16 E2A and the Development of B and T Lymphocytes; 17 The Role of BCL-6 in Normal Lymphoid System and non-Hodgkin's Lymphomas; 18 The Role of Octamer Factors and Their Coactivators in the Lymphoid System; 19 The Role of Early B-Cell Factor in B-Lymphocyte Development; IV. TRANSCRIPTION FACTORS INVOLVED IN LEUKEMIAS DUE TO CHROMOSOMAL TRANSLOCATION 20 The Role of RARa and Its Fusion Partners in Acute Promyelocytic Leukemia21 The Leukemogenic Function of the inv(16) Fusion Gene CBFB-MYH11; 22 EVI1 Rearrangements in Malignant Hematopoiesis; 23 t(8; 21) AML and the AML1/ETO Fusion Gene: From Clinical Syndrome to Paradigm for the Molecular Basis of Acute Leukemia; 24 TEL/ETV6 Gene Rearrangements in Human Leukemias; 25 MLL in Normal and Malignant Hematopoiesis; 26 Coactivators and Leukemia: The Acetylation Connection with Translocations Involving CBP, p300, TIF2, MOZ, and MLL; 27 The LMO2 Master Gene Its Role as a Transcription Regulator Determining Cell Fate in Leukemogenesis and in Hematopoiesis28 The Acetyltransferases CBP and p300: Molecular Integrators of Hematopoietic Transcription Involved in Chromosomal Translocations; V. ONCOGENESIS AND HEMATOPOIESIS; 29 The Roles of the c-myc and c-myb Oncogenes in Hematopoiesis and Leukemogenesis; 30 NF-kB in Cell Life and Death; VI. SUMMARY OF TRANSCRIPTION FACTORS IMPLICATED IN HEMATOPOIESIS: IN VIVO STUDIES; 31 Transcription Factors Implicated in Hematopoiesis: In Vivo Studies 32 Chromosomal Translocations Associated with Disruption of Transcriptional Regulators in Leukemia and Lymphoma |
| Record Nr. | UNINA-9910142505503321 |
| New York, : Wiley-Liss, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transcription factors [[electronic resource] ] : normal and malignant development of blood cells / / edited by Katya Ravid, Jonathan Licht
| Transcription factors [[electronic resource] ] : normal and malignant development of blood cells / / edited by Katya Ravid, Jonathan Licht |
| Pubbl/distr/stampa | New York, : Wiley-Liss, c2001 |
| Descrizione fisica | 1 online resource (642 p.) |
| Disciplina |
612.1/1
616.15 |
| Altri autori (Persone) |
RavidKatya
LichtJonathan D |
| Soggetto topico |
Hematopoiesis
Genetic regulation Leukemia - Genetic aspects Transcription factors Genetic transcription |
| ISBN |
1-280-36661-3
9786610366613 0-470-34865-8 0-471-46106-7 0-471-22388-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TRANSCRIPTION FACTORS; CONTENTS; Introduction; Contributors; I TRANSCRIPTION FACTORS AND THE MEGAKARYOCYTIC AND ERYTHROID LINEAGES; 1 The Role of GATA-1 and FOG in Erythroid and Megakaryocytic Differentiation; 2 Regulation of Megakaryocyte and Erythroid Differentiation by NF-E2; 3 Transcription Factors Involved in Lineage-Specific Gene Expression During Megakaryopoiesis; 4 Role of TAL1/SCL Transcription Factor in Normal and Leukemic Hematopoiesis; 5 EKLF and the Development of the Erythroid Lineage; II TRANSCRIPTION FACTORS AND THE MYELOID LINEAGE
6 RUNX1(AML1) and CBFB: Genes Required for the Development of All Definitive Hematopoietic Lineages7 PU.1 and the Development of the Myeloid Lineage; 8 CCAAT/Enhancer-Binding Proteins in Myeloid Cells; 9 Homeobox Gene Networks and the Regulation of Hematopoiesis; 10 The Role of Retinoic Acid Receptors in Myeloid Differentiation; 11 Transcriptional Targets of the Vitamin D(3) Receptor During Myeloid Cell Differentiation; III TRANSCRIPTION FACTORS AND THE LYMPHOID LINEAGE; 12 The Role of Ikaros Family Genes in Lymphopcyte Differentiation and Proliferation 13 The Role of PU.1 in B-Lymphocyte Development and Function14 The Role of Pax5 (BSAP) in Early and Late B-Cell Development; 15 Janus Kinases and STAT Family Transcription Factors: Their Role in the Function and Development of Lymphoid Cells; 16 E2A and the Development of B and T Lymphocytes; 17 The Role of BCL-6 in Normal Lymphoid System and non-Hodgkin's Lymphomas; 18 The Role of Octamer Factors and Their Coactivators in the Lymphoid System; 19 The Role of Early B-Cell Factor in B-Lymphocyte Development; IV. TRANSCRIPTION FACTORS INVOLVED IN LEUKEMIAS DUE TO CHROMOSOMAL TRANSLOCATION 20 The Role of RARa and Its Fusion Partners in Acute Promyelocytic Leukemia21 The Leukemogenic Function of the inv(16) Fusion Gene CBFB-MYH11; 22 EVI1 Rearrangements in Malignant Hematopoiesis; 23 t(8; 21) AML and the AML1/ETO Fusion Gene: From Clinical Syndrome to Paradigm for the Molecular Basis of Acute Leukemia; 24 TEL/ETV6 Gene Rearrangements in Human Leukemias; 25 MLL in Normal and Malignant Hematopoiesis; 26 Coactivators and Leukemia: The Acetylation Connection with Translocations Involving CBP, p300, TIF2, MOZ, and MLL; 27 The LMO2 Master Gene Its Role as a Transcription Regulator Determining Cell Fate in Leukemogenesis and in Hematopoiesis28 The Acetyltransferases CBP and p300: Molecular Integrators of Hematopoietic Transcription Involved in Chromosomal Translocations; V. ONCOGENESIS AND HEMATOPOIESIS; 29 The Roles of the c-myc and c-myb Oncogenes in Hematopoiesis and Leukemogenesis; 30 NF-kB in Cell Life and Death; VI. SUMMARY OF TRANSCRIPTION FACTORS IMPLICATED IN HEMATOPOIESIS: IN VIVO STUDIES; 31 Transcription Factors Implicated in Hematopoiesis: In Vivo Studies 32 Chromosomal Translocations Associated with Disruption of Transcriptional Regulators in Leukemia and Lymphoma |
| Record Nr. | UNINA-9910830726003321 |
| New York, : Wiley-Liss, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transcription factors : normal and malignant development of blood cells / / edited by Katya Ravid, Jonathan Licht
| Transcription factors : normal and malignant development of blood cells / / edited by Katya Ravid, Jonathan Licht |
| Pubbl/distr/stampa | New York, : Wiley-Liss, c2001 |
| Descrizione fisica | 1 online resource (642 p.) |
| Disciplina |
612.1/1
616.15 |
| Altri autori (Persone) |
RavidKatya
LichtJonathan D |
| Soggetto topico |
Hematopoiesis
Genetic regulation Leukemia - Genetic aspects Transcription factors Genetic transcription |
| ISBN |
9786610366613
9781280366611 1280366613 9780470348659 0470348658 9780471461067 0471461067 9780471223887 0471223883 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TRANSCRIPTION FACTORS; CONTENTS; Introduction; Contributors; I TRANSCRIPTION FACTORS AND THE MEGAKARYOCYTIC AND ERYTHROID LINEAGES; 1 The Role of GATA-1 and FOG in Erythroid and Megakaryocytic Differentiation; 2 Regulation of Megakaryocyte and Erythroid Differentiation by NF-E2; 3 Transcription Factors Involved in Lineage-Specific Gene Expression During Megakaryopoiesis; 4 Role of TAL1/SCL Transcription Factor in Normal and Leukemic Hematopoiesis; 5 EKLF and the Development of the Erythroid Lineage; II TRANSCRIPTION FACTORS AND THE MYELOID LINEAGE
6 RUNX1(AML1) and CBFB: Genes Required for the Development of All Definitive Hematopoietic Lineages7 PU.1 and the Development of the Myeloid Lineage; 8 CCAAT/Enhancer-Binding Proteins in Myeloid Cells; 9 Homeobox Gene Networks and the Regulation of Hematopoiesis; 10 The Role of Retinoic Acid Receptors in Myeloid Differentiation; 11 Transcriptional Targets of the Vitamin D(3) Receptor During Myeloid Cell Differentiation; III TRANSCRIPTION FACTORS AND THE LYMPHOID LINEAGE; 12 The Role of Ikaros Family Genes in Lymphopcyte Differentiation and Proliferation 13 The Role of PU.1 in B-Lymphocyte Development and Function14 The Role of Pax5 (BSAP) in Early and Late B-Cell Development; 15 Janus Kinases and STAT Family Transcription Factors: Their Role in the Function and Development of Lymphoid Cells; 16 E2A and the Development of B and T Lymphocytes; 17 The Role of BCL-6 in Normal Lymphoid System and non-Hodgkin's Lymphomas; 18 The Role of Octamer Factors and Their Coactivators in the Lymphoid System; 19 The Role of Early B-Cell Factor in B-Lymphocyte Development; IV. TRANSCRIPTION FACTORS INVOLVED IN LEUKEMIAS DUE TO CHROMOSOMAL TRANSLOCATION 20 The Role of RARa and Its Fusion Partners in Acute Promyelocytic Leukemia21 The Leukemogenic Function of the inv(16) Fusion Gene CBFB-MYH11; 22 EVI1 Rearrangements in Malignant Hematopoiesis; 23 t(8; 21) AML and the AML1/ETO Fusion Gene: From Clinical Syndrome to Paradigm for the Molecular Basis of Acute Leukemia; 24 TEL/ETV6 Gene Rearrangements in Human Leukemias; 25 MLL in Normal and Malignant Hematopoiesis; 26 Coactivators and Leukemia: The Acetylation Connection with Translocations Involving CBP, p300, TIF2, MOZ, and MLL; 27 The LMO2 Master Gene Its Role as a Transcription Regulator Determining Cell Fate in Leukemogenesis and in Hematopoiesis28 The Acetyltransferases CBP and p300: Molecular Integrators of Hematopoietic Transcription Involved in Chromosomal Translocations; V. ONCOGENESIS AND HEMATOPOIESIS; 29 The Roles of the c-myc and c-myb Oncogenes in Hematopoiesis and Leukemogenesis; 30 NF-kB in Cell Life and Death; VI. SUMMARY OF TRANSCRIPTION FACTORS IMPLICATED IN HEMATOPOIESIS: IN VIVO STUDIES; 31 Transcription Factors Implicated in Hematopoiesis: In Vivo Studies 32 Chromosomal Translocations Associated with Disruption of Transcriptional Regulators in Leukemia and Lymphoma |
| Altri titoli varianti | Normal and malignant development of blood cells |
| Record Nr. | UNINA-9911019789303321 |
| New York, : Wiley-Liss, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||