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Computational methods for next generation sequencing data analysis / / edited by Ion Măndoiu, Alexander Zelikovsky
| Computational methods for next generation sequencing data analysis / / edited by Ion Măndoiu, Alexander Zelikovsky |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , [2016] |
| Descrizione fisica | 1 online resource (461 p.) |
| Disciplina | 611/.0181663 |
| Collana | Wiley series on bioinformatics : computational techniques and engineering |
| Soggetto topico |
Nucleotide sequence - Methodology
Nucleotide sequence - Data processing |
| ISBN |
1-119-27217-3
1-119-27216-5 1-119-27218-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Contributors; Preface; About the Companion Website; Part I Computing and Experimental Infrastructure for NGS; Chapter 1 Cloud Computing for Next-Generation Sequencing Data Analysis; 1.1 Introduction; 1.2 Challenges for NGS Data Analysis; 1.3 Background For Cloud Computing and its Programming Models; 1.4 Cloud Computing Services for NGS Data Analysis; 1.5 Conclusions and Future Directions; References; Chapter 2 Introduction to the Analysis of Environmental Sequence Information Using Metapathways; 2.1 Introduction & Overview; 2.2 Background
2.3 Metapathways Processes2.4 Big Data Processing; 2.5 Downstream Analyses; 2.6 Conclusions; References; Chapter 3 Pooling Strategy for Massive Viral Sequencing; 3.1 Introduction; 3.2 Design of Pools for Big Viral Data; 3.3 Deconvolution of Viral Samples From Pools; 3.4 Performance of Pooling Methods on Simulated Data; 3.5 Experimental Validation of Pooling Strategy; 3.6 Conclusion; References; Chapter 4 Applications of High-Fidelity Sequencing Protocol to RNA Viruses; 4.1 Introduction; 4.2 High-Fidelity Sequencing Protocol; 4.3 Assembly of High-Fidelity Sequencing Data 4.4 Performance of VGA on Simulated Data4.5 Performance of Existing Viral Assemblers on Simulated Consensus Error-Corrected Reads; 4.6 Performance of VGA on Real Hiv Data; 4.7 Comparison of Alignment on Error-Corrected Reads; 4.8 Evaluating of Error Correction Tools Based on High-Fidelity Sequencing Reads; Acknowledgment; References; Part II Genomics and Epigenomics; Chapter 5 Scaffolding Algorithms; 5.1 Scaffolding; 5.2 State-of-The-Art Scaffolding Tools; 5.3 Recent Scaffolding Tools; 5.4 Scaffolding Software Evaluation; References; Chapter 6 Genomic Variants Detection and Genotyping 6.1 Introduction6.2 Methods for Detection and Genotyping OF SNPs and Small Indels; 6.3 Methods for Detection and Genotyping of CNVs; 6.4 Putting Everything Together; References; Chapter 7 Discovering and Genotyping Twilight Zone Deletions; 7.1 Introduction; 7.2 Notation; 7.3 Non-Twilight-Zone Deletion Discovery; 7.4 Discovering ""Twilight Zone"" Deletions: New Solutions; 7.5 Genotyping ""Twilight Zone"" Deletions; 7.6 Results; 7.7 Discussion; 7.8 Availability; Acknowledgments; References; Chapter 8 Computational Approaches for Finding Long Insertions and Deletions with NGS Data 8.1 Background8.2 Methods; 8.3 Applications; 8.4 Conclusions and Future Directions; Acknowledgment; References; Chapter 9 Computational Approaches in Next-Generation Sequencing Data Analysis for Genome-Wide DNA Methylation Studies; 9.1 Introduction; 9.2 Enrichment-Based Approaches; 9.3 Bisulfite Treatment-Based Approaches; 9.4 Conclusion; References; Chapter 10 Bisulfite-Conversion-Based Methods for DNA Methylation Sequencing Data Analysis; 10.1 Introduction; 10.2 The Problem of Mapping BS-Treated Reads; 10.3 Algorithmic Approaches to the Problem Of Mapping BS-Treated Reads 10.4 Methylation Estimation |
| Record Nr. | UNINA-9910135021603321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Computational methods for next generation sequencing data analysis / / edited by Ion Măndoiu, Alexander Zelikovsky
| Computational methods for next generation sequencing data analysis / / edited by Ion Măndoiu, Alexander Zelikovsky |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , [2016] |
| Descrizione fisica | 1 online resource (461 p.) |
| Disciplina | 611/.0181663 |
| Collana | Wiley series on bioinformatics : computational techniques and engineering |
| Soggetto topico |
Nucleotide sequence - Methodology
Nucleotide sequence - Data processing |
| ISBN |
1-119-27217-3
1-119-27216-5 1-119-27218-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Contributors; Preface; About the Companion Website; Part I Computing and Experimental Infrastructure for NGS; Chapter 1 Cloud Computing for Next-Generation Sequencing Data Analysis; 1.1 Introduction; 1.2 Challenges for NGS Data Analysis; 1.3 Background For Cloud Computing and its Programming Models; 1.4 Cloud Computing Services for NGS Data Analysis; 1.5 Conclusions and Future Directions; References; Chapter 2 Introduction to the Analysis of Environmental Sequence Information Using Metapathways; 2.1 Introduction & Overview; 2.2 Background
2.3 Metapathways Processes2.4 Big Data Processing; 2.5 Downstream Analyses; 2.6 Conclusions; References; Chapter 3 Pooling Strategy for Massive Viral Sequencing; 3.1 Introduction; 3.2 Design of Pools for Big Viral Data; 3.3 Deconvolution of Viral Samples From Pools; 3.4 Performance of Pooling Methods on Simulated Data; 3.5 Experimental Validation of Pooling Strategy; 3.6 Conclusion; References; Chapter 4 Applications of High-Fidelity Sequencing Protocol to RNA Viruses; 4.1 Introduction; 4.2 High-Fidelity Sequencing Protocol; 4.3 Assembly of High-Fidelity Sequencing Data 4.4 Performance of VGA on Simulated Data4.5 Performance of Existing Viral Assemblers on Simulated Consensus Error-Corrected Reads; 4.6 Performance of VGA on Real Hiv Data; 4.7 Comparison of Alignment on Error-Corrected Reads; 4.8 Evaluating of Error Correction Tools Based on High-Fidelity Sequencing Reads; Acknowledgment; References; Part II Genomics and Epigenomics; Chapter 5 Scaffolding Algorithms; 5.1 Scaffolding; 5.2 State-of-The-Art Scaffolding Tools; 5.3 Recent Scaffolding Tools; 5.4 Scaffolding Software Evaluation; References; Chapter 6 Genomic Variants Detection and Genotyping 6.1 Introduction6.2 Methods for Detection and Genotyping OF SNPs and Small Indels; 6.3 Methods for Detection and Genotyping of CNVs; 6.4 Putting Everything Together; References; Chapter 7 Discovering and Genotyping Twilight Zone Deletions; 7.1 Introduction; 7.2 Notation; 7.3 Non-Twilight-Zone Deletion Discovery; 7.4 Discovering ""Twilight Zone"" Deletions: New Solutions; 7.5 Genotyping ""Twilight Zone"" Deletions; 7.6 Results; 7.7 Discussion; 7.8 Availability; Acknowledgments; References; Chapter 8 Computational Approaches for Finding Long Insertions and Deletions with NGS Data 8.1 Background8.2 Methods; 8.3 Applications; 8.4 Conclusions and Future Directions; Acknowledgment; References; Chapter 9 Computational Approaches in Next-Generation Sequencing Data Analysis for Genome-Wide DNA Methylation Studies; 9.1 Introduction; 9.2 Enrichment-Based Approaches; 9.3 Bisulfite Treatment-Based Approaches; 9.4 Conclusion; References; Chapter 10 Bisulfite-Conversion-Based Methods for DNA Methylation Sequencing Data Analysis; 10.1 Introduction; 10.2 The Problem of Mapping BS-Treated Reads; 10.3 Algorithmic Approaches to the Problem Of Mapping BS-Treated Reads 10.4 Methylation Estimation |
| Record Nr. | UNINA-9910812209403321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genomes, evolution, and culture : past, present, and future of humankind / / Rene J. Herrera, Ralph Garcia-Bertrand, Francisco M. Salzano
| Genomes, evolution, and culture : past, present, and future of humankind / / Rene J. Herrera, Ralph Garcia-Bertrand, Francisco M. Salzano |
| Autore | Herrera Rene J. |
| Pubbl/distr/stampa | Chichester, West Sussex, UK ; ; Hoboken, NJ : , : Wiley Blackwell, , 2016 |
| Descrizione fisica | 1 online resource (267 p.) |
| Disciplina | 611/.0181663 |
| Soggetto topico |
Human genome
Evolution (Biology) Culture |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-118-87638-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The history of human evolutionary genetics -- The human genome: structure, function, and variation -- Population structure -- Genetic variability -- Gene and genomic dynamics -- Human origins and early diasporas -- Culture -- Health and disease -- Recent human evolution : an integrative approach -- Bioethics : consequences and implications of genetic technology on human evolution -- Future of human evolution. |
| Record Nr. | UNINA-9910154851303321 |
Herrera Rene J.
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| Chichester, West Sussex, UK ; ; Hoboken, NJ : , : Wiley Blackwell, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genomes, evolution, and culture : past, present, and future of humankind / / Rene J. Herrera, Ralph Garcia-Bertrand, Francisco M. Salzano
| Genomes, evolution, and culture : past, present, and future of humankind / / Rene J. Herrera, Ralph Garcia-Bertrand, Francisco M. Salzano |
| Autore | Herrera Rene J. |
| Pubbl/distr/stampa | Chichester, West Sussex, UK ; ; Hoboken, NJ : , : Wiley Blackwell, , 2016 |
| Descrizione fisica | 1 online resource (267 pages) : illustrations (some color), maps (some color) |
| Disciplina | 611/.0181663 |
| Soggetto topico |
Culture
Evolution (Biology) Human genome |
| ISBN |
1-118-87638-5
1-118-87639-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The history of human evolutionary genetics -- The human genome: structure, function, and variation -- Population structure -- Genetic variability -- Gene and genomic dynamics -- Human origins and early diasporas -- Culture -- Health and disease -- Recent human evolution : an integrative approach -- Bioethics : consequences and implications of genetic technology on human evolution -- Future of human evolution. |
| Record Nr. | UNINA-9910795802803321 |
|
Herrera Rene J.
|
||
| Chichester, West Sussex, UK ; ; Hoboken, NJ : , : Wiley Blackwell, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genomes, evolution, and culture : past, present, and future of humankind / / Rene J. Herrera, Ralph Garcia-Bertrand, Francisco M. Salzano
| Genomes, evolution, and culture : past, present, and future of humankind / / Rene J. Herrera, Ralph Garcia-Bertrand, Francisco M. Salzano |
| Autore | Herrera Rene J. |
| Pubbl/distr/stampa | Chichester, West Sussex, UK ; ; Hoboken, NJ : , : Wiley Blackwell, , 2016 |
| Descrizione fisica | 1 online resource (267 pages) : illustrations (some color), maps (some color) |
| Disciplina | 611/.0181663 |
| Soggetto topico |
Culture
Evolution (Biology) Human genome |
| ISBN |
1-118-87638-5
1-118-87639-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The history of human evolutionary genetics -- The human genome: structure, function, and variation -- Population structure -- Genetic variability -- Gene and genomic dynamics -- Human origins and early diasporas -- Culture -- Health and disease -- Recent human evolution : an integrative approach -- Bioethics : consequences and implications of genetic technology on human evolution -- Future of human evolution. |
| Record Nr. | UNINA-9910814698103321 |
|
Herrera Rene J.
|
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| Chichester, West Sussex, UK ; ; Hoboken, NJ : , : Wiley Blackwell, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mysterious World of the Human Genome
| Mysterious World of the Human Genome |
| Autore | Ryan Frank |
| Pubbl/distr/stampa | HarperCollins UK |
| Disciplina | 611/.0181663 |
| ISBN | 0-00-812210-5 |
| Formato | Musica  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910148929703321 |
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Ryan Frank
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| HarperCollins UK | ||
| Musica | ||
| Lo trovi qui: Univ. Federico II | ||
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