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The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.]
| The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 |
| Descrizione fisica | 1 online resource (311 p.) |
| Disciplina |
572.591935
599.35/3138 |
| Altri autori (Persone) | LamoreuxM. Lynn |
| Soggetto topico |
Mice - Color - Genetics
Mice as laboratory animals |
| ISBN |
1-282-49198-9
9786612491986 1-4443-1965-5 1-4443-1966-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Colors of Mice; Contents; Preface; Acknowledgments; Statement regarding the use of pictures; Statement regarding nomenclature; Part I Introduction to the Pigmentary System; 1 Introduction to the Pigmentary System; 1.1 Introduction; 1.2 Colors of vertebrate animals; 1.3 Other pigment cells; 1.4 The epidermal melanin unit; 1.5 Mammalian hair; 1.6 Melanosome biogenesis and translocation; 1.7 Melanin; 1.8 Hair growth; 1.9 Hair growth cycles; 1.10 Embryonic development of the pigment cell lineage; 1.11 Pigment cells in culture; 1.12 Conclusion; Appendix: color loci of the mouse
Part II The Pigmentary Loci2 Introduction to Mutant Pigmentary Genes; 2.1 Defects of normal melanocyte development: white spotting and graying with age; 2.2 Defects in normal melanosome development: albinism; 2.3 Transport of melanosomes to other cells: the 'dilute' phenotype; 2.4 Pigment-type switching: from eumelanogenesis to pheomelanogenesis; 3 White Spotting and Progressive Graying; 3.1 Definitions and general background; 3.2 Pigment-cell development: developmental biology; 3.3 Cellular signaling pathways for melanocytes; 3.4 Pigment phenotypes and the classical white-spotting genes 3.5 The head, heart, ears, and eyes4 'Albinism' and the Failure of Normal Melanosome Maturation; 4.1 Background; 4.2 The melanosomal matrix; 4.3 The enzymes that catalyze melanogenesis; 4.4 Membrane proteins that regulate the internal milieu of the melanosome; 4.5 Protein processing and routing to the maturing melanosome; 4.6 Melanosome transport; 5 Pigment-Type Switching; 5.1 Introduction; 5.2 Yellow phenotypes; 5.3 Melanin pigment; 5.4 Melanogenesis and the eumelanin/pheomelanin switch mechanism; 5.5 Signaling the switch mechanism at the cellular level; 5.6 Yellow genes Part III Technology and Resources6 Novel Mouse Pigmentary Mutants Generated by Genetic Manipulation; 6.1 Introduction; 6.2 Mouse transgenesis: generation of genetically engineered mice; 6.3 Coat-color transgenic mice; 6.4 The coat-color mutants generated by gene targeting; 6.5 Influence of the genetic background; 6.6 Conclusions; 7 Other Species and Other Resources; 7.1 Introduction; 7.2 Resources; 7.3 Other species; References; Index |
| Record Nr. | UNINA-9910140612503321 |
| Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.]
| The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 |
| Descrizione fisica | 1 online resource (311 p.) |
| Disciplina |
572.591935
599.35/3138 |
| Altri autori (Persone) | LamoreuxM. Lynn |
| Soggetto topico |
Mice - Color - Genetics
Mice as laboratory animals |
| ISBN |
1-282-49198-9
9786612491986 1-4443-1965-5 1-4443-1966-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Colors of Mice; Contents; Preface; Acknowledgments; Statement regarding the use of pictures; Statement regarding nomenclature; Part I Introduction to the Pigmentary System; 1 Introduction to the Pigmentary System; 1.1 Introduction; 1.2 Colors of vertebrate animals; 1.3 Other pigment cells; 1.4 The epidermal melanin unit; 1.5 Mammalian hair; 1.6 Melanosome biogenesis and translocation; 1.7 Melanin; 1.8 Hair growth; 1.9 Hair growth cycles; 1.10 Embryonic development of the pigment cell lineage; 1.11 Pigment cells in culture; 1.12 Conclusion; Appendix: color loci of the mouse
Part II The Pigmentary Loci2 Introduction to Mutant Pigmentary Genes; 2.1 Defects of normal melanocyte development: white spotting and graying with age; 2.2 Defects in normal melanosome development: albinism; 2.3 Transport of melanosomes to other cells: the 'dilute' phenotype; 2.4 Pigment-type switching: from eumelanogenesis to pheomelanogenesis; 3 White Spotting and Progressive Graying; 3.1 Definitions and general background; 3.2 Pigment-cell development: developmental biology; 3.3 Cellular signaling pathways for melanocytes; 3.4 Pigment phenotypes and the classical white-spotting genes 3.5 The head, heart, ears, and eyes4 'Albinism' and the Failure of Normal Melanosome Maturation; 4.1 Background; 4.2 The melanosomal matrix; 4.3 The enzymes that catalyze melanogenesis; 4.4 Membrane proteins that regulate the internal milieu of the melanosome; 4.5 Protein processing and routing to the maturing melanosome; 4.6 Melanosome transport; 5 Pigment-Type Switching; 5.1 Introduction; 5.2 Yellow phenotypes; 5.3 Melanin pigment; 5.4 Melanogenesis and the eumelanin/pheomelanin switch mechanism; 5.5 Signaling the switch mechanism at the cellular level; 5.6 Yellow genes Part III Technology and Resources6 Novel Mouse Pigmentary Mutants Generated by Genetic Manipulation; 6.1 Introduction; 6.2 Mouse transgenesis: generation of genetically engineered mice; 6.3 Coat-color transgenic mice; 6.4 The coat-color mutants generated by gene targeting; 6.5 Influence of the genetic background; 6.6 Conclusions; 7 Other Species and Other Resources; 7.1 Introduction; 7.2 Resources; 7.3 Other species; References; Index |
| Record Nr. | UNINA-9910828001303321 |
| Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||