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Molecular and quantitative animal genetics / / edited by Hasan Khatib ; contributors Jennifer Minick Bormann [and thirty two others]
| Molecular and quantitative animal genetics / / edited by Hasan Khatib ; contributors Jennifer Minick Bormann [and thirty two others] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , 2015 |
| Descrizione fisica | 1 online resource (331 p.) |
| Disciplina | 591.3/5 |
| Soggetto topico |
Animal genetics
Intellectual property |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-118-67737-4
1-118-67732-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Machine generated contents note: Contributors, xiii Manuscript reviewers, xvPreface, xvii1 Decoding and Encoding the "DNA" of Teaching and Learning in College Classrooms 1Michel A. Wattiaux Section 1: Quantitative and Population Genetics 132 Mating Systems: Inbreeding and Inbreeding Depression 15 David L. Thomas 3 Genomic Selection, Inbreeding, and Crossbreeding in Dairy Cattle 25 Kent Weige l4 Basic Genetic Models for Quantitative Traits 33 Guilherme J. M. Rosa 5 Heritability and Repeatability 39 Guilherme J. M. Rosa 6 Applications of Statistics in Quantitative Traits 43 Hayrettin Okut Section 2: Applications of Genetics and Genomics to Livestock and Companion Animal Species 657 Genetic Improvement of Beef Cattle 67 Michael D. MacNeil 8 Genetic Improvement in Sheep through Selection 73 David L. Thomas 9 Genetic Improvement Programs for Dairy Cattle 85 Kent Weigel 10 Genetic and Genomic Improvement of Pigs 97 Max F. Rothschild 11 Equine Genetics 107 Jennifer Minick Bormann 12 Genetics and Genomics of the Domestic Dog 121 Leigh Anne Clark and Alison Starr-Moss 13 The Sheep Genome 131 Noelle E. Cockett and Chunhua Wu 14 Goat Genetics and Genomic Progress 137 Mulumebet Worku Section 3: Molecular Genetics of Production and Economically Important Traits 14315 Bioinformatics in Animal Genetics 145 Jose A. Carrillo and Jiuzhou Song 16 Genome-wide Association Studies in Pedigreed Populations 155 Dirk-Jan De Koning 17 Molecular Genetics Techniques and High Throughput Technologies 163 Wen Huang 18 Single Genes in Animal Breeding 177 Brian W. Kirkpatrick 19 Molecular Genetics of Coat Color: It is more than Just Skin Deep 187 Samantha Brooks 20 Molecular Genetics-Nutrition Interactions in Ruminant Fatty Acid Metabolism and Meat Quality 197 Aduli E.O. Malau-Aduli and Benjamin W.B. Holman 21 Nutritional Epigenomics 215 Congjun Li Section 4: Genetics of Embryo Development and Fertility 22722 Genomics of Sex Determination and Dosage Compensation 229 Jenifer Cruickshank and Christopher H. Chandler2 3 Functional Genomics of Mammalian Gametes and Preimplantation Embryos 239 Sule Dogan, Aruna Govindaraju, Elizabeth A. Crate, and Erdogan Memili 24 The Genetics of In Vitro Produced Embryos 257 Ashley Driver Section 5: Genetics of Animal Health and Biotechnology 26325 Understanding the Major Histocompatibility Complex and Immunoglobulin Genes 265 Michael G. Gonda 26 Livestock and Companion Animal Genetics: Genetics of Infectious Disease Susceptibility 275 Michael G. Gonda 27 Animal Genetics and Welfare 283 Amin A. Fadl and Mark E. Cook 28 Animal Biotechnology: Scientific, Regulatory and Public Acceptance Issues Associated with Cloned and Genetically Engineered Animals 289 Alison L. Van Eenennaam29 Intellectual Property Rights and Animal Genetic Resources 303 Jennifer Long and Max F. Rothschild Index 311. |
| Record Nr. | UNINA-9910460200503321 |
| Hoboken, New Jersey : , : Wiley Blackwell, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular and quantitative animal genetics / / edited by Hasan Khatib
| Molecular and quantitative animal genetics / / edited by Hasan Khatib |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , c2015 |
| Descrizione fisica | 1 online resource (331 pages) : illustrations (some color) |
| Disciplina | 591.3/5 |
| Soggetto topico |
Animal genetics
Intellectual property Animals Genetics Molecular Biology |
| ISBN |
1118677323
9781118677322 |
| Classificazione |
481.39
467 QH 432 591.3/5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | und |
| Record Nr. | UNINA-9910796080803321 |
| Hoboken, New Jersey : , : Wiley Blackwell, , c2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular and quantitative animal genetics / / edited by Hasan Khatib
| Molecular and quantitative animal genetics / / edited by Hasan Khatib |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , c2015 |
| Descrizione fisica | 1 online resource (331 pages) : illustrations (some color) |
| Disciplina | 591.3/5 |
| Soggetto topico |
Animal genetics
Intellectual property Animals Genetics Molecular Biology |
| ISBN |
1118677323
9781118677322 |
| Classificazione |
481.39
467 QH 432 591.3/5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | und |
| Nota di contenuto |
Cover -- Title page -- Copyright page -- Contents -- Contributors -- Manuscript Reviewers -- Preface -- 1: Decoding and Encoding the "DNA" of Teaching and Learning in College Classrooms -- Introduction -- Teaching and learning: definitions -- Understanding learning -- Research in learning -- Transferable and life-long learning skills and aptitudes -- Understanding teaching -- Research in teaching -- Implications for classroom design in the twenty-first century -- Architecture of an effective classroom -- Instructional features for life-long learning -- Toward an active learning classroom -- Final thoughts -- References -- Review questions -- Section 1: Quantitative and Population Genetics -- 2: Mating Systems: Inbreeding and Inbreeding Depression -- Introduction -- Inbreeding -- Genetic defects -- Inbreeding depression -- Cause of inbreeding depression -- Quantifying inbreeding -- Inbreeding coefficient -- Inbreeding coefficient formula -- Calculating inbreeding coefficients -- Genomics and inbreeding -- Summary -- Further reading -- References -- Review questions -- 3: Genomic Selection, Inbreeding, and Crossbreeding in Dairy Cattle -- Introduction -- Genomic selection -- Genotyping tools -- Parentage verification and discovery -- Individual genes with large effects -- Genotype imputation -- Genome-enabled breeding value prediction -- Applications of genomics to selection of elite breeding stock -- Applications of genomics to improvement of replacement heifers on commercial farms -- Crossbreeding -- Breed characteristics and complementarity -- Heterosis and crossbreeding systems -- Experiments and field results -- Inbreeding and genetic defects -- Relationships, inbreeding, and effective population size -- Inherited defects -- Inbreeding depression for quantitative traits -- Managing inbreeding and genetic diversity -- Summary -- References.
Review questions -- 4: Basic Genetic Model for Quantitative Traits -- Introduction -- Quantitative traits -- Expected value and variance: the normal distribution -- Basic genetic model for quantitative traits -- Heritability and selection -- Predicting rate of genetic change from selection -- Further reading -- References -- 5: Heritability and Repeatability -- Introduction -- Heritability -- Estimation of heritability and variance components -- Prediction of breeding values and of response to selection -- Repeatability -- References -- 6: Applications of Statistics in Quantitative Traits -- Population and sample -- Parameter and statistics -- Descriptive statistics -- Types of variables -- Descriptive statistics categorical (qualitative) data -- Descriptive statistics for quantitative variables -- Comparing of arithmetic mean, median, and mode -- Measures of dispersion -- Graphically examining the distribution of the data -- Graphical presentation of categorical data -- Graphical presentation of quantitative data -- Normal distribution -- Area under the curve -- Standard normal distributions -- Exploring relationships between variables -- Covariance -- Correlation -- Regression -- Summary -- Population and sample -- Descriptive statistics -- Graphically examining the distribution of the data -- Normal distribution -- Exploring relationships between variables -- Appendix 6.1 -- Further reading -- References -- Review questions -- Section 2: Applications of Genetics and Genomics to Livestock and Companion Animal Species -- 7: Genetic Improvement of Beef Cattle -- Introduction -- Single trait selection -- National cattle evaluation -- Multiple trait selection -- Summary -- Further reading -- References -- 8: Genetic Improvement in Sheep through Selection -- Products from sheep -- Selection among breeds. Selection within a breed or population and the Key Equation -- Adjustment for environmental effects -- Phenotypic selection -- Estimated breeding values (EBV) -- Using multiple sources of information -- Genetic correlations -- Selection intensity -- Generation interval (L) -- Predicting progress from selection -- National genetic improvement programs -- Summary -- Further reading -- References -- Review questions -- 9: Genetic Improvement Programs for Dairy Cattle -- Introduction -- Data collection infrastructure -- Milk recording -- Pedigree information -- Type classification -- Health, fertility, calving ability, and longevity data -- Progeny testing and AI programs -- Estimation of breeding values -- Pre-adjustment for known environmental effects -- Contemporary groups -- Animal model genetic evaluations -- Four paths of selection -- Selection for increased productivity -- Milk yield -- Component percentages and cheese yield -- Maintenance costs and efficiency of milk production -- Net merit index (income portion) -- Selection for functional traits -- Calving performance -- Male and female fertility -- Udder health and mastitis -- Mobility -- Frame size and body condition -- Culling and longevity -- Net merit index (expense portion) -- Sire selection -- Selection index or independent culling levels? -- Reliability and management of risk -- Gender-enhanced semen -- Summary -- Further reading -- References -- Review questions -- 10: Genetic and Genomic Improvement of Pigs -- Introduction -- Domestication of swine and breed development -- Methods of selection and mating systems -- Traits of economic importance -- Development of molecular genetic approaches -- QTL, candidate genes, and genetic improvement -- Sequencing the pig genome -- Genomic selection -- Databases -- Cloning, transgenics, and breeding pigs as biological models. Future applications to genetic improvement -- Acknowledgments -- Further reading -- References -- Review questions -- 11: Equine Genetics -- Color -- Introduction -- Base colors -- Modifiers to base colors -- Other modifications -- White markings -- Paint/pinto patterns -- Genetic defects -- Introduction -- Dominant disorders -- Recessive disorders -- The genetics of health -- Inbreeding and relationship -- Inbreeding -- Relationship -- Selection and improvement -- Quantitative genetics -- Genetic improvement -- Genetic evaluation -- New technologies -- Cloning -- Equine genomics -- Further reading -- References -- Review questions -- 12: Genetics and Genomics of the Domestic Dog -- Introduction to canine research -- Domestication -- Breeding -- A model organism -- Genetic testing -- The dog genome -- Genomic tools -- Whole genome sequence -- Genome structure -- Uncovering the genetic basis of phenotypes -- Candidate gene approaches -- Genome-wide approaches -- Quantitative traits -- Future challenges -- Behavior -- Cancer -- Summary -- Further reading -- References -- Review questions -- 13: The Sheep Genome -- Investment in sheep genome research -- Overview of the sheep genome -- Genomic resources in sheep -- Physical map -- Linkage maps -- Radiation hybrid maps -- SNP arrays -- BAC library and end sequences -- Whole genome reference sequence -- Whole genome assembly -- Application of genomic resources -- Summary -- References -- Review questions -- 14: Goat Genetics and Genomic Progress -- Introduction -- Genetics and goat domestication -- Taxonomy -- Goat chromosome number and structure -- Patterns of inheritance -- Mendelian traits and exceptions -- Quantitative trail loci (QTL) -- Progress in goat genomics -- Biotechnologies and goat genetics -- Cloning -- Transgenic animals -- Summary -- Further reading -- Review questions. Section 3: Molecular Genetics of Production and Economically Important Traits -- 15: Bioinformatics in Animal Genetics -- Introduction -- Bioinformatics and animal genetics -- The importance of bioinformatics in genomics research -- Genome sequencing -- Alignment -- Genome assembly -- Annotation -- Gene expression -- Microarrays -- RNA-Seq -- Gene regulation -- Epigenetics -- Genomic data manipulation -- R language -- Bioconductor -- Web-based tools -- Bioinformatics perspectives in animal genetics -- References -- Review questions -- 16: Genome-wide Association Studies in Pedigreed Populations -- Introduction -- Experimental designs -- Genotyping and linkage disequilibrium -- Quality control -- The statistical analysis -- Significance testing -- Inspection of GWAS results -- Dealing with population structure -- Methods and tools for GWAS in pedigreed populations -- PLINK -- TASSEL -- EMMA/EMMAX -- GenABEL -- Things to remember about analysis -- What did we miss? -- Acknowledgments -- References -- 17: Molecular Genetics Techniques and High Throughput Technologies -- Central dogma of molecular biology -- Review of properties of nucleic acids -- Purification of nucleic acids from cells -- Determining the quantity and purity of nucleic acids -- UV spectrophotometry -- Fluorometry -- Gel electrophoresis -- Polymerase chain reaction (PCR) -- Determining the identity of DNA -- Chain termination method -- Restriction Fragment Length Polymorphism (RFLP) for variant genotyping -- Concept of parallelization and high throughput assays -- Microarray technology -- Array fabrication -- Labeling RNA -- Hybridization of cRNA -- Quantitation of hybridization -- Other applications of microarrays -- Next generation sequencing technology -- Introduction to next generation sequencing -- Unique challenges of next generation sequencing. Applications of next generation sequencing technologies. |
| Record Nr. | UNINA-9910813941103321 |
| Hoboken, New Jersey : , : Wiley Blackwell, , c2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||