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Application of reverse genetic systems to study Beet soil-borne mosaic virus and Beet necrotic yellow vein virus molecular biology, the interaction of species and their use as biotechnological tool / / Marlene Laufer
| Application of reverse genetic systems to study Beet soil-borne mosaic virus and Beet necrotic yellow vein virus molecular biology, the interaction of species and their use as biotechnological tool / / Marlene Laufer |
| Autore | Laufer Marlene |
| Pubbl/distr/stampa | Göttingen : , : Cuvillier Verlag, , [2018] |
| Descrizione fisica | 1 online resource (155 pages) |
| Disciplina | 579.25 |
| Collana | Aus dem Institut für Zuckerrübenforschung Göttingen |
| Soggetto topico | RNA viruses |
| ISBN | 3-7369-8814-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910796806003321 |
Laufer Marlene
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| Göttingen : , : Cuvillier Verlag, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Application of reverse genetic systems to study Beet soil-borne mosaic virus and Beet necrotic yellow vein virus molecular biology, the interaction of species and their use as biotechnological tool / / Marlene Laufer
| Application of reverse genetic systems to study Beet soil-borne mosaic virus and Beet necrotic yellow vein virus molecular biology, the interaction of species and their use as biotechnological tool / / Marlene Laufer |
| Autore | Laufer Marlene |
| Pubbl/distr/stampa | Göttingen : , : Cuvillier Verlag, , [2018] |
| Descrizione fisica | 1 online resource (155 pages) |
| Disciplina | 579.25 |
| Collana | Aus dem Institut für Zuckerrübenforschung Göttingen |
| Soggetto topico | RNA viruses |
| ISBN | 3-7369-8814-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910823859603321 |
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Laufer Marlene
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| Göttingen : , : Cuvillier Verlag, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current topics in microbiology and immunology
| Current topics in microbiology and immunology |
| Pubbl/distr/stampa | Berlin, : Springer |
| Disciplina | 579.25 |
| ISSN | 0070-217X |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-990008948500403321 |
| Berlin, : Springer | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
| Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff |
| Autore | Liebhoff Anna-Maria |
| Edizione | [1. Auflage.] |
| Pubbl/distr/stampa | Göttingen : , : Cuvillier Verlag, , [2021] |
| Descrizione fisica | 1 online resource (143 pages) |
| Disciplina | 579.25 |
| Soggetto topico | RNA viruses - Research - Methodology |
| ISBN | 3-7369-6409-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Intro -- 1 Introduction -- 2 Biological background -- 2.1 Ribonucleic acid (RNA) -- 2.2 Small RNA -- 2.3 Sequencing -- 2.4 Microbiology -- 2.5 Neurodegenerative diseases -- 2.6 Pathogens in neurological diseases -- 3 Bioinformatics background -- 3.1 Data sources -- 3.2 Metadata and biological ontologies -- 3.3 Read alignment -- 3.4 Comparative analysis -- 3.5 Metagenomic analysis -- 3.6 Integrated analysis pipelines -- 4 Computer science background -- 4.1 Web development -- 4.2 Data science and machine learning -- 5 Small RNA Expression Atlas (SEA) -- 5.1 Background -- 5.2 System architecture -- 5.3 Implementation -- 5.4 System behavior -- 5.5 Results -- 6 Biological discoveries through SEA -- 6.1 Tissue specificity of small RNA -- 6.2 User data and Parkinson's disease -- 6.3 Pathogens in neurodegenerative diseases -- 6.4 Sex specificity of small RNA in human body -- 6.5 Discussion -- 7 Pathogen detection in RNA-seq data -- 7.1 Background -- 7.2 Identification algorithm -- 7.3 Performance measures -- 7.4 Evaluation -- 8 Path(ogen)s to disease -- 8.1 Analysis pipeline -- 8.2 Burkholderia stabilis in frontotemporal dementia -- 8.3 Discussion -- 9 Conclusion -- Bibliography -- A SEA JSON communication objects -- B Pathonoia algorithms -- C Detailed analysis results. |
| Record Nr. | UNINA-9910794549303321 |
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Liebhoff Anna-Maria
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||
| Göttingen : , : Cuvillier Verlag, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
| Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff |
| Autore | Liebhoff Anna-Maria |
| Edizione | [1. Auflage.] |
| Pubbl/distr/stampa | Göttingen : , : Cuvillier Verlag, , [2021] |
| Descrizione fisica | 1 online resource (143 pages) |
| Disciplina | 579.25 |
| Soggetto topico | RNA viruses - Research - Methodology |
| ISBN | 3-7369-6409-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Intro -- 1 Introduction -- 2 Biological background -- 2.1 Ribonucleic acid (RNA) -- 2.2 Small RNA -- 2.3 Sequencing -- 2.4 Microbiology -- 2.5 Neurodegenerative diseases -- 2.6 Pathogens in neurological diseases -- 3 Bioinformatics background -- 3.1 Data sources -- 3.2 Metadata and biological ontologies -- 3.3 Read alignment -- 3.4 Comparative analysis -- 3.5 Metagenomic analysis -- 3.6 Integrated analysis pipelines -- 4 Computer science background -- 4.1 Web development -- 4.2 Data science and machine learning -- 5 Small RNA Expression Atlas (SEA) -- 5.1 Background -- 5.2 System architecture -- 5.3 Implementation -- 5.4 System behavior -- 5.5 Results -- 6 Biological discoveries through SEA -- 6.1 Tissue specificity of small RNA -- 6.2 User data and Parkinson's disease -- 6.3 Pathogens in neurodegenerative diseases -- 6.4 Sex specificity of small RNA in human body -- 6.5 Discussion -- 7 Pathogen detection in RNA-seq data -- 7.1 Background -- 7.2 Identification algorithm -- 7.3 Performance measures -- 7.4 Evaluation -- 8 Path(ogen)s to disease -- 8.1 Analysis pipeline -- 8.2 Burkholderia stabilis in frontotemporal dementia -- 8.3 Discussion -- 9 Conclusion -- Bibliography -- A SEA JSON communication objects -- B Pathonoia algorithms -- C Detailed analysis results. |
| Record Nr. | UNINA-9910818329903321 |
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Liebhoff Anna-Maria
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| Göttingen : , : Cuvillier Verlag, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The evolution and emergence of RNA viruses / / Edward C. Holmes
| The evolution and emergence of RNA viruses / / Edward C. Holmes |
| Autore | Holmes Edward C. |
| Pubbl/distr/stampa | Oxford, England : , : Oxford University Press, , 2009 |
| Descrizione fisica | 1 online resource (267 p.) |
| Disciplina | 579.25 |
| Collana | Oxford Series in Ecology and Evolution |
| Soggetto topico |
RNA viruses
Viruses - Evolution Viral genetics Virus diseases |
| ISBN | 0-19-154941-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; 1 Introduction; 1.1 Why study RNA virus evolution?; 1.1.1 Ways to study viral evolution; 1.1.2 The scope of this book; 1.2 RNA viruses and evolutionary biology; 1.2.1 The RNA virus world; 1.3 The basics of viral biology; 1.3.1 A cursory history of virology; 1.3.2 Virology 101; 1.3.3 Exploring the virosphere; 2 The origins of RNA viruses; 2.1 Introduction; 2.1.1 The perils of deep viral phylogeny; 2.2 Theories for the origin of RNA viruses; 2.2.1 The regressive origin theory; 2.2.2 RNA viruses as escaped genes; 2.2.3 RNA viruses and the RNA world; 2.2.4 Eigen's paradox
2.2.5 The taxonomic distribution of RNA viruses2.2.6 Conserved protein structures; 2.3 Deep phylogenetic relationships among RNA viruses; 2.3.1 The 'higher-order' relationships of RNA viruses; 2.3.2 Phylogenies based on genome organization; 2.3.3 Phylogenies based on protein structure; 2.4 RNA viruses and the evolution of the genetic code; 3 The mechanisms of RNA virus evolution; 3.1 The evolutionary dynamics of RNA viruses; 3.1.1 Mutation rates in RNA viruses and their determinants; 3.1.2 A comparison of substitution rates in viruses; 3.1.3 Differences in viral generation time 3.1.4 Slowly evolving RNA viruses?3.1.5 Rapidly evolving ssDNA viruses; 3.1.6 What sets the rate of RNA virus evolution?; 3.1.7 Trade-offs and the evolution of mutation rates; 3.1.8 Mutation rates and mutational loads; 3.1.9 Are RNA viruses trapped by high mutation rates?; 3.2 Recombination and reassortment in RNA virus evolution; 3.2.1 Recombination frequency in RNA viruses; 3.2.2 Detecting recombination in RNA viruses; 3.2.3 What determines the rate of recombination in RNA viruses?; 3.2.4 Recombination and deleterious mutation 3.3 Natural selection, genetic drift, and the genetics of adaptation3.3.1 Effective population sizes in viral evolution; 3.3.2 Transmission bottlenecks; 3.3.3 The dynamics of allele fixation: estimating selection coefficients; 3.3.4 The importance of hitch-hiking; 3.3.5 Patterns of synonymous and nonsynonymous evolution; 3.3.6 Natural selection and transmission mode; 3.3.7 Escape from intrinsic immunity; 3.3.8 Strictly neutral evolution in RNA viruses?; 3.3.9 Determinants of codon bias (and nucleotide composition) in RNA viruses; 3.4 Deleterious mutation and RNA virus evolution 3.4.1 Deleterious mutation and intra-host genetic diversity3.4.2 The importance of defective interfering particles and complementation; 3.4.3 Complementation may be commonplace in RNA viruses; 3.5 Epistasis in RNA virus evolution; 3.5.1 Epistasis and robustness; 3.5.2 The importance of RNA secondary structure; 3.5.3 Convergence and pleiotropy; 3.6 The importance of intra-host viral diversity; 4 The RNA virus quasispecies; 4.1 What is a quasispecies?; 4.2 The great quasispecies debate; 4.2.1 What's in a name: quasispecies or polymorphism? 4.2.2 Is quasispecies theory different from 'classical' population genetics? |
| Record Nr. | UNINA-9910798280503321 |
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Holmes Edward C.
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||
| Oxford, England : , : Oxford University Press, , 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The evolution and emergence of RNA viruses / / Edward C. Holmes
| The evolution and emergence of RNA viruses / / Edward C. Holmes |
| Autore | Holmes Edward C. |
| Pubbl/distr/stampa | Oxford, England : , : Oxford University Press, , 2009 |
| Descrizione fisica | 1 online resource (267 p.) |
| Disciplina | 579.25 |
| Collana | Oxford Series in Ecology and Evolution |
| Soggetto topico |
RNA viruses
Viruses - Evolution Viral genetics Virus diseases |
| ISBN | 0-19-154941-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; 1 Introduction; 1.1 Why study RNA virus evolution?; 1.1.1 Ways to study viral evolution; 1.1.2 The scope of this book; 1.2 RNA viruses and evolutionary biology; 1.2.1 The RNA virus world; 1.3 The basics of viral biology; 1.3.1 A cursory history of virology; 1.3.2 Virology 101; 1.3.3 Exploring the virosphere; 2 The origins of RNA viruses; 2.1 Introduction; 2.1.1 The perils of deep viral phylogeny; 2.2 Theories for the origin of RNA viruses; 2.2.1 The regressive origin theory; 2.2.2 RNA viruses as escaped genes; 2.2.3 RNA viruses and the RNA world; 2.2.4 Eigen's paradox
2.2.5 The taxonomic distribution of RNA viruses2.2.6 Conserved protein structures; 2.3 Deep phylogenetic relationships among RNA viruses; 2.3.1 The 'higher-order' relationships of RNA viruses; 2.3.2 Phylogenies based on genome organization; 2.3.3 Phylogenies based on protein structure; 2.4 RNA viruses and the evolution of the genetic code; 3 The mechanisms of RNA virus evolution; 3.1 The evolutionary dynamics of RNA viruses; 3.1.1 Mutation rates in RNA viruses and their determinants; 3.1.2 A comparison of substitution rates in viruses; 3.1.3 Differences in viral generation time 3.1.4 Slowly evolving RNA viruses?3.1.5 Rapidly evolving ssDNA viruses; 3.1.6 What sets the rate of RNA virus evolution?; 3.1.7 Trade-offs and the evolution of mutation rates; 3.1.8 Mutation rates and mutational loads; 3.1.9 Are RNA viruses trapped by high mutation rates?; 3.2 Recombination and reassortment in RNA virus evolution; 3.2.1 Recombination frequency in RNA viruses; 3.2.2 Detecting recombination in RNA viruses; 3.2.3 What determines the rate of recombination in RNA viruses?; 3.2.4 Recombination and deleterious mutation 3.3 Natural selection, genetic drift, and the genetics of adaptation3.3.1 Effective population sizes in viral evolution; 3.3.2 Transmission bottlenecks; 3.3.3 The dynamics of allele fixation: estimating selection coefficients; 3.3.4 The importance of hitch-hiking; 3.3.5 Patterns of synonymous and nonsynonymous evolution; 3.3.6 Natural selection and transmission mode; 3.3.7 Escape from intrinsic immunity; 3.3.8 Strictly neutral evolution in RNA viruses?; 3.3.9 Determinants of codon bias (and nucleotide composition) in RNA viruses; 3.4 Deleterious mutation and RNA virus evolution 3.4.1 Deleterious mutation and intra-host genetic diversity3.4.2 The importance of defective interfering particles and complementation; 3.4.3 Complementation may be commonplace in RNA viruses; 3.5 Epistasis in RNA virus evolution; 3.5.1 Epistasis and robustness; 3.5.2 The importance of RNA secondary structure; 3.5.3 Convergence and pleiotropy; 3.6 The importance of intra-host viral diversity; 4 The RNA virus quasispecies; 4.1 What is a quasispecies?; 4.2 The great quasispecies debate; 4.2.1 What's in a name: quasispecies or polymorphism? 4.2.2 Is quasispecies theory different from 'classical' population genetics? |
| Record Nr. | UNINA-9910814101303321 |
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Holmes Edward C.
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| Oxford, England : , : Oxford University Press, , 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marburg- and Ebolaviruses : From Ecosystems to Molecules / / edited by Elke Mühlberger, Lisa L. Hensley, Jonathan S. Towner
| Marburg- and Ebolaviruses : From Ecosystems to Molecules / / edited by Elke Mühlberger, Lisa L. Hensley, Jonathan S. Towner |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (X, 460 p.) |
| Disciplina | 579.25 |
| Collana | Current Topics in Microbiology and Immunology |
| Soggetto topico |
Virology
Infectious diseases Epidemiology Infectious Diseases |
| ISBN | 3-319-68948-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Filovirus Research: How it began -- Ecology of Filoviruses -- West Africa 2013 Ebola: From Virus Outbreak to Humanitarian Crisis -- Clinical Management of Ebola Virus Disease Patients in Low Resource Settings -- Clinical Management of Patients with Ebola Virus Disease in High Resource Settings -- Ebola Virus Disease in Humans: Pathophysiology and Immunity -- Nonhuman Primate Models of Ebola Virus Disease -- Small Animal Models for Studying Filovirus Pathogenesis -- Accelerating Vaccine Development during the West African Ebola Virus Disease Outbreak -- Therapeutics against Filovirus Infection -- Filovirus Strategies to Escape Antiviral Responses -- Mechanisms of Filovirus Entry -- Inside the Cell: Assembly of Filoviruses -- Filovirus Structural Biology: The Molecules in the Machine -- Reverse Genetics of Filoviruses -- Guide to the Correct Use of Filoviral Nomenclature. |
| Record Nr. | UNINA-9910253957303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Basis of Resilience : Adapting to a Changing Environment / / by Patrick L. Iversen
| Molecular Basis of Resilience : Adapting to a Changing Environment / / by Patrick L. Iversen |
| Autore | Iversen Patrick L |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (325 pages) |
| Disciplina | 579.25 |
| Soggetto topico |
Pharmacology
Molecular biology Pharmacology/Toxicology Molecular Medicine |
| ISBN | 3-319-98164-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Prologue -- Preface -- Social Entropy -- Virus among Us -- Non-linear Anomalies -- Bacterial Infectious Disease -- Cure 2000 -- Chemicals in the Environment -- Immune Defense -- Metabolic Defense -- Analog Genetics -- Eteplirsen -- Regulating Resilience. |
| Record Nr. | UNINA-9910298410703321 |
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Iversen Patrick L
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multiplication of RNA plant viruses / by C. L. Mandahar
| Multiplication of RNA plant viruses / by C. L. Mandahar |
| Autore | Mandahar, C. L. |
| Pubbl/distr/stampa | Dordrecht, : Springer, c2006 |
| Descrizione fisica | xix, 329 p. ; 28 cm |
| Disciplina |
581.234
579.25 |
| Soggetto non controllato |
Virologia vegetale
Virus RNA |
| ISBN | 978-1-4020-4724-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-990009610110403321 |
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Mandahar, C. L.
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| Dordrecht, : Springer, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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