Cellular and Molecular Control of Neuronal Migration / / edited by Laurent Nguyen, Simon Hippenmeyer |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (194 p.) |
Disciplina | 573.84 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Neurosciences
Neurobiology Human anatomy Microscopy Developmental biology Cell biology Anatomy Biological Microscopy Developmental Biology Cell Biology |
ISBN | 94-007-7687-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- Molecular Pathways Controlling the Sequential Steps of Cortical Neuron Migration -- The Dynamics of Neuronal Migration -- The Impact of JNK on Neuronal Migration -- Novel Functions of Core Cell Cycle Regulators in Neuronal Migration -- Microtubules and Neurodevelopmental Disease: The Movers and the Makers -- Mark/Par-1 Marking the Polarity of Migrating Neurons -- The PAR Polarity Complex and Cerebellar Granule Neuron Migration.- Spinal Motor Neuron Migration and the Significance of Topographic Organization in the Nervous System -- Extracellular Signals Controlling Neuroblast Migration in the Postnatal Brain. |
Record Nr. | UNINA-9910298306603321 |
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Journal of neurochemistry |
Pubbl/distr/stampa | New York, : Raven Press |
Disciplina |
616.8042
573.84 |
ISSN | 0022-3042 |
Formato | Materiale a stampa |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Note periodicità | Mensile |
Record Nr. | UNINA-990008991140403321 |
New York, : Raven Press | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Molecular neurology [[electronic resource] /] / Stephen Waxman |
Autore | Waxman Stephen G |
Pubbl/distr/stampa | Burlington, MA, : Elsevier Academic Press, c2007 |
Descrizione fisica | 1 online resource (597 p.) |
Disciplina |
573.84
616.8 |
Soggetto topico |
Molecular neurobiology
Molecular biology |
Soggetto genere / forma | Electronic books. |
ISBN |
1-281-03719-2
9786611037192 0-08-054618-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Molecular Neurology; Copyright Page; Contents; Contributor's List; Preface; Section I: Principles of Molecular Neurology; Chapter 1: Genetics as a Tool in Neurology; I. Introduction; II. Structure and Function of Genes and Chromosomes; III. Genetic Medicine; IV. The Neurogenetic Evaluation; V. Identification of Human Disease Genes; VI. Methods for Human Molecular Genetic Analysis; VII. Treatment of Genetic Diseases; References; Chapter 2: Neurology and Genomic Medicine; I. Introduction; II. Basic Concepts; III. The Human Genome Project (HGP) and Haplotype Mapping (HapMap) Project
IV. Family HistoryV. Genetic Mechanisms; VI. Pharmacogenetics; VII. Gene-Gene and Gene-Environment Interactions; VIII. Comparative Genomic Hybridization (CGH); IX. Mitochondria and the Mitochondrial Genome (mtDNA); X. Summary; References; Chapter 3: Mitochondrial Function and Dysfunction in the Nervous System; I. Introduction; II. Structure and Functions of Mitochondria; III. Mitochondria in Mechanisms of Neuronal Cell Death and Neurological Disease; IV. Roles of Mitochondrial Dysfunction in Common Neurodegenerative Diseases; V. Conclusions; References Cahpter 4: Neuronal Channels and ReceptorsI. Introduction; II. Nomenclature; III. Structure and Function; IV. Physiological Roles; V. Neurological Disorders Caused by Channelopathies; References; Chapter 5: Protein Misfolding, Chaperone Networks, and the Heat Shock Response in the Nervous System; I. Introduction; II. Role of Molecular Chaperones in Protein Folding Quality Control; III. Regulation of Chaperone Expression: The Heat Shock Response; IV. Role of Molecular Chaperones in Neurodegenerative Diseases; V. Chaperone Hypotheses; VI. Therapeutic Avenues; References Chapter 6: Metabolic Biopsy of the BrainI. Phosphorus Magnetic Resonance Spectroscopy; II. The Phosphocreatine Shuttle Hypothesis; III. Magnetization Transfer Measurements of ATP and Phosphocreatine Synthesis; IV. Hydrogen (Proton) Spectroscopy; V. Carbon Spectroscopy; VI. MR Spectroscopic Measurements of Cerebral Lactate; VII. The Astrocyte-Neuron Lactate Shuttle Hypothesis; VIII. Cerebral Ammonia Metabolism; IX. Summary; References; Chapter 7: Gene Therapy Approaches in Neurology; I. Why Use Gene Transfer in the Development of Novel Therapies?; II. Gene Transfer Strategies III. Development of Neurological Gene TherapyIV. Conclusions-Future Developments; References; Chapter 8: Programmed Cell Death and Its Role in Neurological Disease; I. Introduction: Neurologists and Cell Death; II. Cell Death: History and Classification; III. Current Status of Programmed Cell Death Studies; IV. Trophic Factors and the Concept of Cellular Dependence; V. Apoptosis Induced by Unfolded, Misfolded, or Alternatively Folded Proteins; VI. Does Programmed Cell Death Play a Role in Neurodegeneration? VII. Are Programmed Cell Death Pathways Appropriate Therapeutic Targets in Neurodegeneration? |
Record Nr. | UNINA-9910458636203321 |
Waxman Stephen G | ||
Burlington, MA, : Elsevier Academic Press, c2007 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Molecular neurology [[electronic resource] /] / Stephen Waxman |
Autore | Waxman Stephen G |
Pubbl/distr/stampa | Burlington, MA, : Elsevier Academic Press, c2007 |
Descrizione fisica | 1 online resource (597 p.) |
Disciplina |
573.84
616.8 |
Altri autori (Persone) | WaxmanStephen G |
Soggetto topico |
Molecular neurobiology
Molecular biology |
ISBN |
1-281-03719-2
9786611037192 0-08-054618-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Molecular Neurology; Copyright Page; Contents; Contributor's List; Preface; Section I: Principles of Molecular Neurology; Chapter 1: Genetics as a Tool in Neurology; I. Introduction; II. Structure and Function of Genes and Chromosomes; III. Genetic Medicine; IV. The Neurogenetic Evaluation; V. Identification of Human Disease Genes; VI. Methods for Human Molecular Genetic Analysis; VII. Treatment of Genetic Diseases; References; Chapter 2: Neurology and Genomic Medicine; I. Introduction; II. Basic Concepts; III. The Human Genome Project (HGP) and Haplotype Mapping (HapMap) Project
IV. Family HistoryV. Genetic Mechanisms; VI. Pharmacogenetics; VII. Gene-Gene and Gene-Environment Interactions; VIII. Comparative Genomic Hybridization (CGH); IX. Mitochondria and the Mitochondrial Genome (mtDNA); X. Summary; References; Chapter 3: Mitochondrial Function and Dysfunction in the Nervous System; I. Introduction; II. Structure and Functions of Mitochondria; III. Mitochondria in Mechanisms of Neuronal Cell Death and Neurological Disease; IV. Roles of Mitochondrial Dysfunction in Common Neurodegenerative Diseases; V. Conclusions; References Cahpter 4: Neuronal Channels and ReceptorsI. Introduction; II. Nomenclature; III. Structure and Function; IV. Physiological Roles; V. Neurological Disorders Caused by Channelopathies; References; Chapter 5: Protein Misfolding, Chaperone Networks, and the Heat Shock Response in the Nervous System; I. Introduction; II. Role of Molecular Chaperones in Protein Folding Quality Control; III. Regulation of Chaperone Expression: The Heat Shock Response; IV. Role of Molecular Chaperones in Neurodegenerative Diseases; V. Chaperone Hypotheses; VI. Therapeutic Avenues; References Chapter 6: Metabolic Biopsy of the BrainI. Phosphorus Magnetic Resonance Spectroscopy; II. The Phosphocreatine Shuttle Hypothesis; III. Magnetization Transfer Measurements of ATP and Phosphocreatine Synthesis; IV. Hydrogen (Proton) Spectroscopy; V. Carbon Spectroscopy; VI. MR Spectroscopic Measurements of Cerebral Lactate; VII. The Astrocyte-Neuron Lactate Shuttle Hypothesis; VIII. Cerebral Ammonia Metabolism; IX. Summary; References; Chapter 7: Gene Therapy Approaches in Neurology; I. Why Use Gene Transfer in the Development of Novel Therapies?; II. Gene Transfer Strategies III. Development of Neurological Gene TherapyIV. Conclusions-Future Developments; References; Chapter 8: Programmed Cell Death and Its Role in Neurological Disease; I. Introduction: Neurologists and Cell Death; II. Cell Death: History and Classification; III. Current Status of Programmed Cell Death Studies; IV. Trophic Factors and the Concept of Cellular Dependence; V. Apoptosis Induced by Unfolded, Misfolded, or Alternatively Folded Proteins; VI. Does Programmed Cell Death Play a Role in Neurodegeneration? VII. Are Programmed Cell Death Pathways Appropriate Therapeutic Targets in Neurodegeneration? |
Record Nr. | UNINA-9910784650603321 |
Waxman Stephen G | ||
Burlington, MA, : Elsevier Academic Press, c2007 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Molecular neurology / / Stephen Waxman |
Autore | Waxman Stephen G |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Burlington, MA, : Elsevier Academic Press, c2007 |
Descrizione fisica | 1 online resource (597 p.) |
Disciplina |
573.84
616.8 |
Soggetto topico |
Molecular neurobiology
Molecular biology |
ISBN |
1-281-03719-2
9786611037192 0-08-054618-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Molecular Neurology; Copyright Page; Contents; Contributor's List; Preface; Section I: Principles of Molecular Neurology; Chapter 1: Genetics as a Tool in Neurology; I. Introduction; II. Structure and Function of Genes and Chromosomes; III. Genetic Medicine; IV. The Neurogenetic Evaluation; V. Identification of Human Disease Genes; VI. Methods for Human Molecular Genetic Analysis; VII. Treatment of Genetic Diseases; References; Chapter 2: Neurology and Genomic Medicine; I. Introduction; II. Basic Concepts; III. The Human Genome Project (HGP) and Haplotype Mapping (HapMap) Project
IV. Family HistoryV. Genetic Mechanisms; VI. Pharmacogenetics; VII. Gene-Gene and Gene-Environment Interactions; VIII. Comparative Genomic Hybridization (CGH); IX. Mitochondria and the Mitochondrial Genome (mtDNA); X. Summary; References; Chapter 3: Mitochondrial Function and Dysfunction in the Nervous System; I. Introduction; II. Structure and Functions of Mitochondria; III. Mitochondria in Mechanisms of Neuronal Cell Death and Neurological Disease; IV. Roles of Mitochondrial Dysfunction in Common Neurodegenerative Diseases; V. Conclusions; References Cahpter 4: Neuronal Channels and ReceptorsI. Introduction; II. Nomenclature; III. Structure and Function; IV. Physiological Roles; V. Neurological Disorders Caused by Channelopathies; References; Chapter 5: Protein Misfolding, Chaperone Networks, and the Heat Shock Response in the Nervous System; I. Introduction; II. Role of Molecular Chaperones in Protein Folding Quality Control; III. Regulation of Chaperone Expression: The Heat Shock Response; IV. Role of Molecular Chaperones in Neurodegenerative Diseases; V. Chaperone Hypotheses; VI. Therapeutic Avenues; References Chapter 6: Metabolic Biopsy of the BrainI. Phosphorus Magnetic Resonance Spectroscopy; II. The Phosphocreatine Shuttle Hypothesis; III. Magnetization Transfer Measurements of ATP and Phosphocreatine Synthesis; IV. Hydrogen (Proton) Spectroscopy; V. Carbon Spectroscopy; VI. MR Spectroscopic Measurements of Cerebral Lactate; VII. The Astrocyte-Neuron Lactate Shuttle Hypothesis; VIII. Cerebral Ammonia Metabolism; IX. Summary; References; Chapter 7: Gene Therapy Approaches in Neurology; I. Why Use Gene Transfer in the Development of Novel Therapies?; II. Gene Transfer Strategies III. Development of Neurological Gene TherapyIV. Conclusions-Future Developments; References; Chapter 8: Programmed Cell Death and Its Role in Neurological Disease; I. Introduction: Neurologists and Cell Death; II. Cell Death: History and Classification; III. Current Status of Programmed Cell Death Studies; IV. Trophic Factors and the Concept of Cellular Dependence; V. Apoptosis Induced by Unfolded, Misfolded, or Alternatively Folded Proteins; VI. Does Programmed Cell Death Play a Role in Neurodegeneration? VII. Are Programmed Cell Death Pathways Appropriate Therapeutic Targets in Neurodegeneration? |
Record Nr. | UNINA-9910820439703321 |
Waxman Stephen G | ||
Burlington, MA, : Elsevier Academic Press, c2007 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|