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Cellular and Molecular Control of Neuronal Migration / / edited by Laurent Nguyen, Simon Hippenmeyer
Cellular and Molecular Control of Neuronal Migration / / edited by Laurent Nguyen, Simon Hippenmeyer
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (194 p.)
Disciplina 573.84
Collana Advances in Experimental Medicine and Biology
Soggetto topico Neurosciences
Neurobiology
Human anatomy
Microscopy
Developmental biology
Cell biology
Anatomy
Biological Microscopy
Developmental Biology
Cell Biology
ISBN 94-007-7687-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Molecular Pathways Controlling the Sequential Steps of Cortical Neuron  Migration -- The Dynamics of Neuronal Migration -- The Impact of JNK on Neuronal Migration -- Novel Functions of Core Cell Cycle Regulators in Neuronal Migration -- Microtubules and Neurodevelopmental Disease: The Movers and the Makers -- Mark/Par-1 Marking the Polarity of Migrating Neurons -- The PAR Polarity Complex and Cerebellar Granule Neuron Migration.- Spinal Motor Neuron Migration and the Significance of Topographic Organization in the Nervous System -- Extracellular Signals Controlling Neuroblast Migration in the Postnatal Brain.
Record Nr. UNINA-9910298306603321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Materiale a stampa
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Journal of neurochemistry
Journal of neurochemistry
Pubbl/distr/stampa New York, : Raven Press
Disciplina 616.8042
573.84
ISSN 0022-3042
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Note periodicità Mensile
Record Nr. UNINA-990008991140403321
New York, : Raven Press
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Molecular neurology [[electronic resource] /] / Stephen Waxman
Molecular neurology [[electronic resource] /] / Stephen Waxman
Autore Waxman Stephen G
Pubbl/distr/stampa Burlington, MA, : Elsevier Academic Press, c2007
Descrizione fisica 1 online resource (597 p.)
Disciplina 573.84
616.8
Soggetto topico Molecular neurobiology
Molecular biology
Soggetto genere / forma Electronic books.
ISBN 1-281-03719-2
9786611037192
0-08-054618-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Molecular Neurology; Copyright Page; Contents; Contributor's List; Preface; Section I: Principles of Molecular Neurology; Chapter 1: Genetics as a Tool in Neurology; I. Introduction; II. Structure and Function of Genes and Chromosomes; III. Genetic Medicine; IV. The Neurogenetic Evaluation; V. Identification of Human Disease Genes; VI. Methods for Human Molecular Genetic Analysis; VII. Treatment of Genetic Diseases; References; Chapter 2: Neurology and Genomic Medicine; I. Introduction; II. Basic Concepts; III. The Human Genome Project (HGP) and Haplotype Mapping (HapMap) Project
IV. Family HistoryV. Genetic Mechanisms; VI. Pharmacogenetics; VII. Gene-Gene and Gene-Environment Interactions; VIII. Comparative Genomic Hybridization (CGH); IX. Mitochondria and the Mitochondrial Genome (mtDNA); X. Summary; References; Chapter 3: Mitochondrial Function and Dysfunction in the Nervous System; I. Introduction; II. Structure and Functions of Mitochondria; III. Mitochondria in Mechanisms of Neuronal Cell Death and Neurological Disease; IV. Roles of Mitochondrial Dysfunction in Common Neurodegenerative Diseases; V. Conclusions; References
Cahpter 4: Neuronal Channels and ReceptorsI. Introduction; II. Nomenclature; III. Structure and Function; IV. Physiological Roles; V. Neurological Disorders Caused by Channelopathies; References; Chapter 5: Protein Misfolding, Chaperone Networks, and the Heat Shock Response in the Nervous System; I. Introduction; II. Role of Molecular Chaperones in Protein Folding Quality Control; III. Regulation of Chaperone Expression: The Heat Shock Response; IV. Role of Molecular Chaperones in Neurodegenerative Diseases; V. Chaperone Hypotheses; VI. Therapeutic Avenues; References
Chapter 6: Metabolic Biopsy of the BrainI. Phosphorus Magnetic Resonance Spectroscopy; II. The Phosphocreatine Shuttle Hypothesis; III. Magnetization Transfer Measurements of ATP and Phosphocreatine Synthesis; IV. Hydrogen (Proton) Spectroscopy; V. Carbon Spectroscopy; VI. MR Spectroscopic Measurements of Cerebral Lactate; VII. The Astrocyte-Neuron Lactate Shuttle Hypothesis; VIII. Cerebral Ammonia Metabolism; IX. Summary; References; Chapter 7: Gene Therapy Approaches in Neurology; I. Why Use Gene Transfer in the Development of Novel Therapies?; II. Gene Transfer Strategies
III. Development of Neurological Gene TherapyIV. Conclusions-Future Developments; References; Chapter 8: Programmed Cell Death and Its Role in Neurological Disease; I. Introduction: Neurologists and Cell Death; II. Cell Death: History and Classification; III. Current Status of Programmed Cell Death Studies; IV. Trophic Factors and the Concept of Cellular Dependence; V. Apoptosis Induced by Unfolded, Misfolded, or Alternatively Folded Proteins; VI. Does Programmed Cell Death Play a Role in Neurodegeneration?
VII. Are Programmed Cell Death Pathways Appropriate Therapeutic Targets in Neurodegeneration?
Record Nr. UNINA-9910458636203321
Waxman Stephen G  
Burlington, MA, : Elsevier Academic Press, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular neurology [[electronic resource] /] / Stephen Waxman
Molecular neurology [[electronic resource] /] / Stephen Waxman
Autore Waxman Stephen G
Pubbl/distr/stampa Burlington, MA, : Elsevier Academic Press, c2007
Descrizione fisica 1 online resource (597 p.)
Disciplina 573.84
616.8
Altri autori (Persone) WaxmanStephen G
Soggetto topico Molecular neurobiology
Molecular biology
ISBN 1-281-03719-2
9786611037192
0-08-054618-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Molecular Neurology; Copyright Page; Contents; Contributor's List; Preface; Section I: Principles of Molecular Neurology; Chapter 1: Genetics as a Tool in Neurology; I. Introduction; II. Structure and Function of Genes and Chromosomes; III. Genetic Medicine; IV. The Neurogenetic Evaluation; V. Identification of Human Disease Genes; VI. Methods for Human Molecular Genetic Analysis; VII. Treatment of Genetic Diseases; References; Chapter 2: Neurology and Genomic Medicine; I. Introduction; II. Basic Concepts; III. The Human Genome Project (HGP) and Haplotype Mapping (HapMap) Project
IV. Family HistoryV. Genetic Mechanisms; VI. Pharmacogenetics; VII. Gene-Gene and Gene-Environment Interactions; VIII. Comparative Genomic Hybridization (CGH); IX. Mitochondria and the Mitochondrial Genome (mtDNA); X. Summary; References; Chapter 3: Mitochondrial Function and Dysfunction in the Nervous System; I. Introduction; II. Structure and Functions of Mitochondria; III. Mitochondria in Mechanisms of Neuronal Cell Death and Neurological Disease; IV. Roles of Mitochondrial Dysfunction in Common Neurodegenerative Diseases; V. Conclusions; References
Cahpter 4: Neuronal Channels and ReceptorsI. Introduction; II. Nomenclature; III. Structure and Function; IV. Physiological Roles; V. Neurological Disorders Caused by Channelopathies; References; Chapter 5: Protein Misfolding, Chaperone Networks, and the Heat Shock Response in the Nervous System; I. Introduction; II. Role of Molecular Chaperones in Protein Folding Quality Control; III. Regulation of Chaperone Expression: The Heat Shock Response; IV. Role of Molecular Chaperones in Neurodegenerative Diseases; V. Chaperone Hypotheses; VI. Therapeutic Avenues; References
Chapter 6: Metabolic Biopsy of the BrainI. Phosphorus Magnetic Resonance Spectroscopy; II. The Phosphocreatine Shuttle Hypothesis; III. Magnetization Transfer Measurements of ATP and Phosphocreatine Synthesis; IV. Hydrogen (Proton) Spectroscopy; V. Carbon Spectroscopy; VI. MR Spectroscopic Measurements of Cerebral Lactate; VII. The Astrocyte-Neuron Lactate Shuttle Hypothesis; VIII. Cerebral Ammonia Metabolism; IX. Summary; References; Chapter 7: Gene Therapy Approaches in Neurology; I. Why Use Gene Transfer in the Development of Novel Therapies?; II. Gene Transfer Strategies
III. Development of Neurological Gene TherapyIV. Conclusions-Future Developments; References; Chapter 8: Programmed Cell Death and Its Role in Neurological Disease; I. Introduction: Neurologists and Cell Death; II. Cell Death: History and Classification; III. Current Status of Programmed Cell Death Studies; IV. Trophic Factors and the Concept of Cellular Dependence; V. Apoptosis Induced by Unfolded, Misfolded, or Alternatively Folded Proteins; VI. Does Programmed Cell Death Play a Role in Neurodegeneration?
VII. Are Programmed Cell Death Pathways Appropriate Therapeutic Targets in Neurodegeneration?
Record Nr. UNINA-9910784650603321
Waxman Stephen G  
Burlington, MA, : Elsevier Academic Press, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular neurology / / Stephen Waxman
Molecular neurology / / Stephen Waxman
Autore Waxman Stephen G
Edizione [1st ed.]
Pubbl/distr/stampa Burlington, MA, : Elsevier Academic Press, c2007
Descrizione fisica 1 online resource (597 p.)
Disciplina 573.84
616.8
Soggetto topico Molecular neurobiology
Molecular biology
ISBN 1-281-03719-2
9786611037192
0-08-054618-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Molecular Neurology; Copyright Page; Contents; Contributor's List; Preface; Section I: Principles of Molecular Neurology; Chapter 1: Genetics as a Tool in Neurology; I. Introduction; II. Structure and Function of Genes and Chromosomes; III. Genetic Medicine; IV. The Neurogenetic Evaluation; V. Identification of Human Disease Genes; VI. Methods for Human Molecular Genetic Analysis; VII. Treatment of Genetic Diseases; References; Chapter 2: Neurology and Genomic Medicine; I. Introduction; II. Basic Concepts; III. The Human Genome Project (HGP) and Haplotype Mapping (HapMap) Project
IV. Family HistoryV. Genetic Mechanisms; VI. Pharmacogenetics; VII. Gene-Gene and Gene-Environment Interactions; VIII. Comparative Genomic Hybridization (CGH); IX. Mitochondria and the Mitochondrial Genome (mtDNA); X. Summary; References; Chapter 3: Mitochondrial Function and Dysfunction in the Nervous System; I. Introduction; II. Structure and Functions of Mitochondria; III. Mitochondria in Mechanisms of Neuronal Cell Death and Neurological Disease; IV. Roles of Mitochondrial Dysfunction in Common Neurodegenerative Diseases; V. Conclusions; References
Cahpter 4: Neuronal Channels and ReceptorsI. Introduction; II. Nomenclature; III. Structure and Function; IV. Physiological Roles; V. Neurological Disorders Caused by Channelopathies; References; Chapter 5: Protein Misfolding, Chaperone Networks, and the Heat Shock Response in the Nervous System; I. Introduction; II. Role of Molecular Chaperones in Protein Folding Quality Control; III. Regulation of Chaperone Expression: The Heat Shock Response; IV. Role of Molecular Chaperones in Neurodegenerative Diseases; V. Chaperone Hypotheses; VI. Therapeutic Avenues; References
Chapter 6: Metabolic Biopsy of the BrainI. Phosphorus Magnetic Resonance Spectroscopy; II. The Phosphocreatine Shuttle Hypothesis; III. Magnetization Transfer Measurements of ATP and Phosphocreatine Synthesis; IV. Hydrogen (Proton) Spectroscopy; V. Carbon Spectroscopy; VI. MR Spectroscopic Measurements of Cerebral Lactate; VII. The Astrocyte-Neuron Lactate Shuttle Hypothesis; VIII. Cerebral Ammonia Metabolism; IX. Summary; References; Chapter 7: Gene Therapy Approaches in Neurology; I. Why Use Gene Transfer in the Development of Novel Therapies?; II. Gene Transfer Strategies
III. Development of Neurological Gene TherapyIV. Conclusions-Future Developments; References; Chapter 8: Programmed Cell Death and Its Role in Neurological Disease; I. Introduction: Neurologists and Cell Death; II. Cell Death: History and Classification; III. Current Status of Programmed Cell Death Studies; IV. Trophic Factors and the Concept of Cellular Dependence; V. Apoptosis Induced by Unfolded, Misfolded, or Alternatively Folded Proteins; VI. Does Programmed Cell Death Play a Role in Neurodegeneration?
VII. Are Programmed Cell Death Pathways Appropriate Therapeutic Targets in Neurodegeneration?
Record Nr. UNINA-9910820439703321
Waxman Stephen G  
Burlington, MA, : Elsevier Academic Press, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui