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Combinatorics of genome rearrangements [[electronic resource] /] / Guillaume Fertin ... [et al.]
| Combinatorics of genome rearrangements [[electronic resource] /] / Guillaume Fertin ... [et al.] |
| Pubbl/distr/stampa | Cambridge, Mass., : MIT Press, c2009 |
| Descrizione fisica | 1 online resource (305 p.) |
| Disciplina | 572.8/77 |
| Altri autori (Persone) | FertinGuillaume <1972-> |
| Collana | Computational molecular biology |
| Soggetto topico |
Translocation (Genetics) - Mathematical models
Translocation (Genetics) - Data processing Combinatorial analysis Genomics - Mathematics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-262-25818-8
0-262-25875-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Genomes as permutations -- Distances between unsigned permutations -- Distances between signed permutations -- Rearrangements of partial orders -- Graph-theoretic and linear algebra formulations -- Generalities -- Distances between arbitrary strings -- Distances between balanced strings -- Paths and cycles -- Cycles of a permutation -- Set systems and the syntenic distance -- Median and halving problems -- Rearrangement phylogenies -- Software -- Open problems. |
| Record Nr. | UNINA-9910455587303321 |
| Cambridge, Mass., : MIT Press, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Combinatorics of genome rearrangements / / Guillaume Fertin [and others]
| Combinatorics of genome rearrangements / / Guillaume Fertin [and others] |
| Pubbl/distr/stampa | Cambridge, Mass., : MIT Press, ©2009 |
| Descrizione fisica | 1 online resource (305 p.) |
| Disciplina | 572.8/77 |
| Altri autori (Persone) | FertinGuillaume <1972-> |
| Collana | Computational molecular biology |
| Soggetto topico |
Translocation (Genetics) - Mathematical models
Translocation (Genetics) - Data processing Combinatorial analysis Genomics - Mathematics |
| Soggetto non controllato | BIOMEDICAL SCIENCES/Quantitative Biology |
| ISBN |
0-262-25818-8
0-262-25875-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Genomes as permutations -- Distances between unsigned permutations -- Distances between signed permutations -- Rearrangements of partial orders -- Graph-theoretic and linear algebra formulations -- Generalities -- Distances between arbitrary strings -- Distances between balanced strings -- Paths and cycles -- Cycles of a permutation -- Set systems and the syntenic distance -- Median and halving problems -- Rearrangement phylogenies -- Software -- Open problems. |
| Record Nr. | UNINA-9910780989903321 |
| Cambridge, Mass., : MIT Press, ©2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Combinatorics of genome rearrangements / / Guillaume Fertin ... [et al.]
| Combinatorics of genome rearrangements / / Guillaume Fertin ... [et al.] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cambridge, Mass., : MIT Press, c2009 |
| Descrizione fisica | 1 online resource (305 p.) |
| Disciplina | 572.8/77 |
| Altri autori (Persone) | FertinGuillaume <1972-> |
| Collana | Computational molecular biology |
| Soggetto topico |
Translocation (Genetics) - Mathematical models
Translocation (Genetics) - Data processing Combinatorial analysis Genomics - Mathematics |
| ISBN |
0-262-25818-8
0-262-25875-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Genomes as permutations -- Distances between unsigned permutations -- Distances between signed permutations -- Rearrangements of partial orders -- Graph-theoretic and linear algebra formulations -- Generalities -- Distances between arbitrary strings -- Distances between balanced strings -- Paths and cycles -- Cycles of a permutation -- Set systems and the syntenic distance -- Median and halving problems -- Rearrangement phylogenies -- Software -- Open problems. |
| Record Nr. | UNINA-9910828373103321 |
| Cambridge, Mass., : MIT Press, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genome instability and transgenerational effects [[electronic resource] /] / Igor Kovalchuk and Olga Kovalchuk, editors
| Genome instability and transgenerational effects [[electronic resource] /] / Igor Kovalchuk and Olga Kovalchuk, editors |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2010 |
| Descrizione fisica | 1 online resource (490 p.) |
| Disciplina | 572.8/77 |
| Altri autori (Persone) |
KovalchukIgor
KovalchukOlga, MD. |
| Collana | Genetics--research and issues series |
| Soggetto topico |
Epigenesis
Mutation (Biology) Variation (Biology) |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61761-663-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""GENOME INSTABILITY AND TRANSGENERATIONAL EFFECTS""; ""GENOME INSTABILITY AND TRANSGENERATIONAL EFFECTS""; ""CONTENTS ""; ""PREFACE ""; ""GENETIC AND EPIGENETIC REGULATION OF TRANSGENERATIONAL CHANGES IN GENOME STABILITY: AN OVERVIEW""; ""REFERENCES ""; ""GENETIC AND EPIGENETIC MECHANISMS ENSURING STABILITY OF MAMMALIAN GENOMES""; ""ABSTRACT ""; ""INTRODUCTION ""; ""GENETIC MECHANISMS OF GENOME STABILITY ""; ""Direct Reversal of Damage ""; ""Base Excision Repair ""; ""Nucleotide Excision Repair ""; ""Mismatch Repair ""; ""Repair of DNA Strand Breaks by Homologous Recombination ""
""Non-Homologous End Joining """"Cell Cycle Checkpoints ""; ""EPIGENETIC REGULATION OF GENOMIC STABILITY ""; ""DNA Methylation ""; ""Histone Modifications ""; ""Short RNA-Mediated Silencing ""; ""CONCLUSION ""; ""REFERENCES ""; ""GENETIC AND EPIGENETIC REGULATION OF GENOME STABILITY IN PLANTS""; ""ABSTRACT ""; ""INTRODUCTION ""; ""1. ENDOGENOUS AND EXOGENOUS FACTORS THAT AFFECT GENOME STABILITY""; ""1.1. Reactive Oxygen Species Challenge DNA the Repair Machinery and Decrease Genome Stability ""; ""1.2. The Choice of DNA Repair Pathway May Regulate Plant Genome Stability "" ""1.3. The Importance of Plant Genome Plasticity for Stress Tolerance and Genome Evolution""""2. MECHANISMS AND FUNCTIONS OF EPIGENETIC REGULATIONS IN THE PLANT GENOME ""; ""2.1. DNA Methylation Is a Critical Component in the System of Epigenetic Modifications in Plants""; ""2.2. Histone Modifications and DNA Methylation Are Interdependent ""; ""2.3. Chromatin Remodeling Shapes Chromatin Structure and Complements DNA and Histone Modifications""; ""3. EPIGENETIC MODIFICATIONS � A STRESS-RESPONSIVE MECHANISM CONTROLLING GENE REGULATION AND GENOME STABILITY"" ""3.1. Effects of Stress on Epigenetic Regulations """"3.2. Small RNAs May Direct Epigenetic Modifications to a Specific Genomic Locus""; ""3.2.1. The Complexity and Functional Redundancy of smRNA Biogenesis Pathways in Arabidopsis ""; ""3.2.2. Mechanisms of smRNA-Directed Epigenetic Regulations ""; ""3.2.3. Small RNA Biogenesis is a Sensitive Stress-Responsive System ""; ""4. INDUCIBLE EPIGENETIC CHANGES MAY CHANGE GENOME STABILITY AND GUIDE GENOME EVOLUTION""; ""CONCLUDING REMARKS ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""EVOLUTION OF THE FPG/NEI FAMILY OF DNA GLYCOSYLASES "" ""ABSTRACT """"ABBREVIATIONS ""; ""INTRODUCTION ""; ""METHODS ""; ""EVENTS IN THE FPG/NEI PHYLOGENY ""; ""Horizontal Transfer ""; ""Changes in Substrate Specificity ""; ""Changes in the Structural Zinc-Finger Motif ""; ""Expansion within the Actinobacteria ""; ""THE ENZYMATIC FUNCTION OF THE FPG2 GLADE REMAINS UNKNOWN ""; ""CONCLUSION ""; ""REFERENCES ""; ""STRESS-INDUCED MUTAGENESIS IN BACTERIA ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""STRESSFUL (MUTAGENIC) FACTORS ""; ""STRESS RESPONSE TO ENDOGENOUS AND EXOGENOUS DNA-DAMAGING AGENTS""; ""TRANSLESION DNA SYNTHESIS "" ""THE GENERAL STRESS RESPONSE "" |
| Record Nr. | UNINA-9910465455103321 |
| New York, : Nova Science Publishers, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genome instability and transgenerational effects [[electronic resource] /] / Igor Kovalchuk and Olga Kovalchuk, editors
| Genome instability and transgenerational effects [[electronic resource] /] / Igor Kovalchuk and Olga Kovalchuk, editors |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2010 |
| Descrizione fisica | 1 online resource (490 p.) |
| Disciplina | 572.8/77 |
| Altri autori (Persone) |
KovalchukIgor
KovalchukOlga, MD. |
| Collana | Genetics--research and issues series |
| Soggetto topico |
Epigenesis
Mutation (Biology) Variation (Biology) |
| ISBN | 1-61761-663-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""GENOME INSTABILITY AND TRANSGENERATIONAL EFFECTS""; ""GENOME INSTABILITY AND TRANSGENERATIONAL EFFECTS""; ""CONTENTS ""; ""PREFACE ""; ""GENETIC AND EPIGENETIC REGULATION OF TRANSGENERATIONAL CHANGES IN GENOME STABILITY: AN OVERVIEW""; ""REFERENCES ""; ""GENETIC AND EPIGENETIC MECHANISMS ENSURING STABILITY OF MAMMALIAN GENOMES""; ""ABSTRACT ""; ""INTRODUCTION ""; ""GENETIC MECHANISMS OF GENOME STABILITY ""; ""Direct Reversal of Damage ""; ""Base Excision Repair ""; ""Nucleotide Excision Repair ""; ""Mismatch Repair ""; ""Repair of DNA Strand Breaks by Homologous Recombination ""
""Non-Homologous End Joining """"Cell Cycle Checkpoints ""; ""EPIGENETIC REGULATION OF GENOMIC STABILITY ""; ""DNA Methylation ""; ""Histone Modifications ""; ""Short RNA-Mediated Silencing ""; ""CONCLUSION ""; ""REFERENCES ""; ""GENETIC AND EPIGENETIC REGULATION OF GENOME STABILITY IN PLANTS""; ""ABSTRACT ""; ""INTRODUCTION ""; ""1. ENDOGENOUS AND EXOGENOUS FACTORS THAT AFFECT GENOME STABILITY""; ""1.1. Reactive Oxygen Species Challenge DNA the Repair Machinery and Decrease Genome Stability ""; ""1.2. The Choice of DNA Repair Pathway May Regulate Plant Genome Stability "" ""1.3. The Importance of Plant Genome Plasticity for Stress Tolerance and Genome Evolution""""2. MECHANISMS AND FUNCTIONS OF EPIGENETIC REGULATIONS IN THE PLANT GENOME ""; ""2.1. DNA Methylation Is a Critical Component in the System of Epigenetic Modifications in Plants""; ""2.2. Histone Modifications and DNA Methylation Are Interdependent ""; ""2.3. Chromatin Remodeling Shapes Chromatin Structure and Complements DNA and Histone Modifications""; ""3. EPIGENETIC MODIFICATIONS � A STRESS-RESPONSIVE MECHANISM CONTROLLING GENE REGULATION AND GENOME STABILITY"" ""3.1. Effects of Stress on Epigenetic Regulations """"3.2. Small RNAs May Direct Epigenetic Modifications to a Specific Genomic Locus""; ""3.2.1. The Complexity and Functional Redundancy of smRNA Biogenesis Pathways in Arabidopsis ""; ""3.2.2. Mechanisms of smRNA-Directed Epigenetic Regulations ""; ""3.2.3. Small RNA Biogenesis is a Sensitive Stress-Responsive System ""; ""4. INDUCIBLE EPIGENETIC CHANGES MAY CHANGE GENOME STABILITY AND GUIDE GENOME EVOLUTION""; ""CONCLUDING REMARKS ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""EVOLUTION OF THE FPG/NEI FAMILY OF DNA GLYCOSYLASES "" ""ABSTRACT """"ABBREVIATIONS ""; ""INTRODUCTION ""; ""METHODS ""; ""EVENTS IN THE FPG/NEI PHYLOGENY ""; ""Horizontal Transfer ""; ""Changes in Substrate Specificity ""; ""Changes in the Structural Zinc-Finger Motif ""; ""Expansion within the Actinobacteria ""; ""THE ENZYMATIC FUNCTION OF THE FPG2 GLADE REMAINS UNKNOWN ""; ""CONCLUSION ""; ""REFERENCES ""; ""STRESS-INDUCED MUTAGENESIS IN BACTERIA ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""STRESSFUL (MUTAGENIC) FACTORS ""; ""STRESS RESPONSE TO ENDOGENOUS AND EXOGENOUS DNA-DAMAGING AGENTS""; ""TRANSLESION DNA SYNTHESIS "" ""THE GENERAL STRESS RESPONSE "" |
| Record Nr. | UNINA-9910791833303321 |
| New York, : Nova Science Publishers, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genome instability and transgenerational effects [[electronic resource] /] / Igor Kovalchuk and Olga Kovalchuk, editors
| Genome instability and transgenerational effects [[electronic resource] /] / Igor Kovalchuk and Olga Kovalchuk, editors |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2010 |
| Descrizione fisica | 1 online resource (490 p.) |
| Disciplina | 572.8/77 |
| Altri autori (Persone) |
KovalchukIgor
KovalchukOlga, MD. |
| Collana | Genetics--research and issues series |
| Soggetto topico |
Epigenesis
Mutation (Biology) Variation (Biology) |
| ISBN | 1-61761-663-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""GENOME INSTABILITY AND TRANSGENERATIONAL EFFECTS""; ""GENOME INSTABILITY AND TRANSGENERATIONAL EFFECTS""; ""CONTENTS ""; ""PREFACE ""; ""GENETIC AND EPIGENETIC REGULATION OF TRANSGENERATIONAL CHANGES IN GENOME STABILITY: AN OVERVIEW""; ""REFERENCES ""; ""GENETIC AND EPIGENETIC MECHANISMS ENSURING STABILITY OF MAMMALIAN GENOMES""; ""ABSTRACT ""; ""INTRODUCTION ""; ""GENETIC MECHANISMS OF GENOME STABILITY ""; ""Direct Reversal of Damage ""; ""Base Excision Repair ""; ""Nucleotide Excision Repair ""; ""Mismatch Repair ""; ""Repair of DNA Strand Breaks by Homologous Recombination ""
""Non-Homologous End Joining """"Cell Cycle Checkpoints ""; ""EPIGENETIC REGULATION OF GENOMIC STABILITY ""; ""DNA Methylation ""; ""Histone Modifications ""; ""Short RNA-Mediated Silencing ""; ""CONCLUSION ""; ""REFERENCES ""; ""GENETIC AND EPIGENETIC REGULATION OF GENOME STABILITY IN PLANTS""; ""ABSTRACT ""; ""INTRODUCTION ""; ""1. ENDOGENOUS AND EXOGENOUS FACTORS THAT AFFECT GENOME STABILITY""; ""1.1. Reactive Oxygen Species Challenge DNA the Repair Machinery and Decrease Genome Stability ""; ""1.2. The Choice of DNA Repair Pathway May Regulate Plant Genome Stability "" ""1.3. The Importance of Plant Genome Plasticity for Stress Tolerance and Genome Evolution""""2. MECHANISMS AND FUNCTIONS OF EPIGENETIC REGULATIONS IN THE PLANT GENOME ""; ""2.1. DNA Methylation Is a Critical Component in the System of Epigenetic Modifications in Plants""; ""2.2. Histone Modifications and DNA Methylation Are Interdependent ""; ""2.3. Chromatin Remodeling Shapes Chromatin Structure and Complements DNA and Histone Modifications""; ""3. EPIGENETIC MODIFICATIONS � A STRESS-RESPONSIVE MECHANISM CONTROLLING GENE REGULATION AND GENOME STABILITY"" ""3.1. Effects of Stress on Epigenetic Regulations """"3.2. Small RNAs May Direct Epigenetic Modifications to a Specific Genomic Locus""; ""3.2.1. The Complexity and Functional Redundancy of smRNA Biogenesis Pathways in Arabidopsis ""; ""3.2.2. Mechanisms of smRNA-Directed Epigenetic Regulations ""; ""3.2.3. Small RNA Biogenesis is a Sensitive Stress-Responsive System ""; ""4. INDUCIBLE EPIGENETIC CHANGES MAY CHANGE GENOME STABILITY AND GUIDE GENOME EVOLUTION""; ""CONCLUDING REMARKS ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""EVOLUTION OF THE FPG/NEI FAMILY OF DNA GLYCOSYLASES "" ""ABSTRACT """"ABBREVIATIONS ""; ""INTRODUCTION ""; ""METHODS ""; ""EVENTS IN THE FPG/NEI PHYLOGENY ""; ""Horizontal Transfer ""; ""Changes in Substrate Specificity ""; ""Changes in the Structural Zinc-Finger Motif ""; ""Expansion within the Actinobacteria ""; ""THE ENZYMATIC FUNCTION OF THE FPG2 GLADE REMAINS UNKNOWN ""; ""CONCLUSION ""; ""REFERENCES ""; ""STRESS-INDUCED MUTAGENESIS IN BACTERIA ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""STRESSFUL (MUTAGENIC) FACTORS ""; ""STRESS RESPONSE TO ENDOGENOUS AND EXOGENOUS DNA-DAMAGING AGENTS""; ""TRANSLESION DNA SYNTHESIS "" ""THE GENERAL STRESS RESPONSE "" |
| Record Nr. | UNINA-9910825076903321 |
| New York, : Nova Science Publishers, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Modern Prometheus : editing the human genome with Crispr-Cas9 / / Jim Kozubek [[electronic resource]]
| Modern Prometheus : editing the human genome with Crispr-Cas9 / / Jim Kozubek [[electronic resource]] |
| Autore | Kozubek Jim |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2016 |
| Descrizione fisica | 1 online resource (xi, 440 pages) : digital, PDF file(s) |
| Disciplina | 572.8/77 |
| Soggetto topico |
Gene targeting
Genomes |
| ISBN |
1-316-78029-5
1-316-78167-4 1-316-78190-9 1-316-62334-3 1-316-77144-X 1-316-78213-1 1-316-78305-7 1-316-78236-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Half-title ; Frontispiece ; Title page ; Copyright information ; Table of contents ; Acknowledgements ; Author's Note ; 1 Crispr, Cas and Capitalists ; 2 The Gene Trade ; 3 Asilomar ; 4 We Can Play God in that Cell ; 5 Modern Prometheus ; 6 Biopolitics ; 7 Life in a Bubble
8 To Summon a Leviathan 9 A Molecular Fairytale ; 10 Secrets from a Freshwater Fish ; 11 Gene Hackers ; 12 Washington ; Notes ; Chapter 1 ; Chapter 2 ; Chapter 3 ; Chapter 4 ; Chapter 5 ; Chapter 6 ; Chapter 8 ; Chapter 9 ; Chapter 10 ; Chapter 11 ; Chapter 12 Bibliography Index |
| Record Nr. | UNINA-9910136604903321 |
Kozubek Jim
|
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| Cambridge : , : Cambridge University Press, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||