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Chromosomes : organization and function / / Adrian T. Sumner
Chromosomes : organization and function / / Adrian T. Sumner
Autore Sumner A. T (Adrian Thomas), <1940->
Pubbl/distr/stampa Oxford ; ; Malden, MA, : Blackwell Pub., 2003
Descrizione fisica 1 online resource (300 p.)
Disciplina 572.8/7
Soggetto topico Chromosomes
ISBN 9786612341687
9781282341685
1282341685
9780470695975
0470695978
9780470695227
0470695226
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chromosomes: Organization and Function; Contents; Preface; Chapter 1: Why study chromosomes?; 1.1 Early studies of chromosomes; 1.2 The origin of genetics, and the chromosome theory of inheritance; 1.3 The chemical nature of genes and chromosomes; 1.4 The position of chromosomes in an age of molecular biology; Website; Chapter 2: Mitosis, meiosis and the cell cycle; 2.1 The necessity for accuracy in the cell cycle; 2.2 The mitotic cycle; 2.3 Essentials of mitosis; 2.4 Other cell-cycle events must be co-ordinated with mitosis; 2.5 Meiosis; 2.6 Accuracy is ensured in cell division
Chapter 3: DNA, the genetic code3.1 Stability and variability of DNA; 3.2 The amount of DNA in nuclei, and the C-value paradox; 3.3 Repetitive DNA - sequences with a function, or just junk?; 3.4 DNA replication; 3.5 5-Methylcytosine - epigenetic modification of DNA; 3.6 DNA damage and repair; 3.7 DNA is dynamic; Websites; Chapter 4: Assembly of chromatin; 4.1 Introduction; 4.2 The nucleosome fibre; 4.3 Packing nucleosomes into solenoids; 4.4 Yet more packing; 4.5 Other ways to pack DNA; 4.6 Summary; Websites; Chapter 5: The chromosomes in interphase
5.1 Interphase nuclei: sites of chromosome activity5.2 How are the chromosomes arranged in the nucleus?; 5.3 Where do replication and transcription take place?; 5.4 The nuclear matrix; 5.5 Other nuclear structures; 5.6 Interphase nuclei are highly organized and dynamic; Website; Chapter 6: Structure of mitotic and meiotic chromosomes; 6.1 Chromosomes of dividing and interphase cells compared; 6.2 Making a mitotic chromosome; 6.3 Loops and scaffolds; 6.4 Chromosome condensation - the final stages; 6.5 Biochemistry of condensation; 6.6 The periphery of the chromosome
6.7 Meiotic and mitotic chromosomes compared6.8 There is still much to be learnt about chromosome structure; Chapter 7: Constitutive heterochromatin; 7.1 What is heterochromatin?; 7.2 Where is constitutive heterochromatin on the chromosomes?; 7.3 What is constitutive heterochromatin made of?; 7.4 What does heterochromatin do?; 7.5 Applications of heterochromatin staining; 7.6 Heterochromatin today; Websites; Chapter 8: Sex chromosomes and sex determination; 8.1 What are sex chromosomes?; 8.2 The evolution of sex chromosomes; 8.3 Sex chromosome systems and mechanisms of sex determination
8.4 Dosage compensation: coping with different numbers of X chromosomes in the two sexes8.5 Sex chromosomes at meiosis and gametogenesis; 8.6 Sex chromosomes: different means, the same ends; Websites; Chapter 9: Imprinting; 9.1 What is imprinting?; 9.2 Which organisms show imprinting?; 9.3 How does imprinting work?; 9.4 What is imprinting for?; Websites; Chapter 10: Euchromatin and the longitudinal differentiation of chromosomes; 10.1 What is euchromatin?; 10.2 Euchromatin and chromosome banding in mammals; 10.3 Longitudinal differentiation of chromosomes in non-mammals
10.4 The how and why of longitudinal differentiation
Record Nr. UNINA-9911019229203321
Sumner A. T (Adrian Thomas), <1940->  
Oxford ; ; Malden, MA, : Blackwell Pub., 2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
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New developments in chromatin research [[electronic resource] /] / Neil M. Simpson and Valerie J. Stewart, editors
New developments in chromatin research [[electronic resource] /] / Neil M. Simpson and Valerie J. Stewart, editors
Pubbl/distr/stampa New York, : Nova Science Publishers, 2012
Descrizione fisica 1 online resource (249 p.)
Disciplina 572.8/7
Altri autori (Persone) SimpsonNeil M
StewartValerie J
Collana Genetics--research and issues
Cell biology research progress
Soggetto topico Chromatin - Research - Methodology
Soggetto genere / forma Electronic books.
ISBN 1-62081-832-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910453223803321
New York, : Nova Science Publishers, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
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New developments in chromatin research [[electronic resource] /] / Neil M. Simpson and Valerie J. Stewart, editors
New developments in chromatin research [[electronic resource] /] / Neil M. Simpson and Valerie J. Stewart, editors
Pubbl/distr/stampa New York, : Nova Science Publishers, 2012
Descrizione fisica 1 online resource (249 p.)
Disciplina 572.8/7
Altri autori (Persone) SimpsonNeil M
StewartValerie J
Collana Genetics--research and issues
Cell biology research progress
Soggetto topico Chromatin - Research - Methodology
ISBN 1-62081-832-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910779608003321
New York, : Nova Science Publishers, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Polyploid and hybrid genomics [[electronic resource] /] / edited by Z. Jeffrey Chen and James A. Birchler
Polyploid and hybrid genomics [[electronic resource] /] / edited by Z. Jeffrey Chen and James A. Birchler
Pubbl/distr/stampa Ames, Iowa, : Wiley-Blackwell, 2013
Descrizione fisica 1 online resource (938 p.)
Disciplina 572.8/7
Altri autori (Persone) ChenZ. Jeffrey
BirchlerJames A <1950-> (James Arthur)
Soggetto topico Polyploidy
Hybridization
ISBN 1-118-55287-3
1-299-46881-0
1-118-55285-7
1-118-55284-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title Page; Copyright; Contributors; Preface; Section I: Genomics of Hybrids; Chapter 1: Yeast Hybrids and Polyploids as Models in Evolutionary Studies; Introduction; Experimental Advantages of Budding Yeasts; Yeast Hybrids; Yeast Polyploids; Paleopolyploidy and Duplicated Genes Retention; Ploidy and Evolution-Theory and Experiments; Genomic Response to Polyploidy and Hybridity; Yeast Hybrids as a Tool for Studying Genomic Regulation; Conclusions; Acknowledgments; References
Chapter 2: Transcriptome Profiling of Drosophila Interspecific Hybrids: Insights into Mechanisms of Regulatory Divergence and Hybrid DysfunctionIntroduction; Gene Expression; Drosophila Hybrids as a Model to Study Transcriptome Divergence; Outlook; References; Chapter 3: cis- and trans-Regulation in Drosophila Interspecific Hybrids; Introduction; Distinguishing between cis- and trans-Regulatory Changes Using eQTL, GWAS, and ASE; Methods Used to Quantify ASE; Studies of cis- and trans-Regulation in Interspecific Hybrids of Drosophila; Insights into Regulatory Evolution
cis- and trans-Regulatory Evolution in Drosophila: A Look AheadReferences; Chapter 4: Gene Expression and Heterosis in Maize Hybrids; Introduction; Gene Expression in Maize Hybrids-Transcript Abundance Relative to Inbred Parents; Allele-Specific Gene Regulation in the Maize Hybrid; Modes of Gene Regulation in the Hybrid; Genetic and Structural Diversities That Contribute to Regulatory Variation; Understanding Heterosis-Various Models; Perspectives; Acknowledgments; References; Chapter 5: Integrating "Omics" Data and Expression QTL to Understand Maize Heterosis; Introduction
Experimental Design and eQTL AnalysiseQTL and the Mechanisms Underlying Gene Regulation; Building Networks and Integrating "omics" to Understand How Variants, in Particular eQTL, Can Result in Phenotypic Variation; Conclusion and Future Prospects; Acknowledgments; References; Chapter 6: Genomics and Heterosis in Hexaploid Wheat; Introduction; Genetic Dissection of Wheat Heterosis; Transcriptome and Proteome Analysis between Wheat Hybrids and Parents; Some Differentially Expressed Patterns are Correlated with Wheat Heterosis
Function Analysis of Differentially Expressed Genes between Wheat Hybrids and Their Parental LinesPossible Regulatory Mechanism Contributing to Differential Gene Expression in Wheat; Physiological Basis of Heterosis for Grain Yield in Wheat; Concluding Remarks; Acknowledgments; References; Chapter 7: Progress of Genomics and Heterosis Studies in Hybrid Rice; Introduction; Progress in the Study of Rice Genomics; Heterosis and Transcriptomics in Hybrid Rice; Epigenetic Modification and Heterosis in Hybrid Rice; Molecular Mechanism behind Heterosis; Perspectives; Acknowledgments; References
Chapter 8: Heterosis: The Case for Single-Gene Overdominance
Record Nr. UNINA-9910141638303321
Ames, Iowa, : Wiley-Blackwell, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Polyploid and hybrid genomics / / edited by Z. Jeffrey Chen and James A. Birchler
Polyploid and hybrid genomics / / edited by Z. Jeffrey Chen and James A. Birchler
Edizione [1st ed.]
Pubbl/distr/stampa Ames, Iowa, : Wiley-Blackwell, 2013
Descrizione fisica 1 online resource (938 p.)
Disciplina 572.8/7
Altri autori (Persone) ChenZ. Jeffrey
BirchlerJames A <1950-> (James Arthur)
Soggetto topico Polyploidy
Hybridization
ISBN 9781118552872
1118552873
9781299468818
1299468810
9781118552858
1118552857
9781118552841
1118552849
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title Page; Copyright; Contributors; Preface; Section I: Genomics of Hybrids; Chapter 1: Yeast Hybrids and Polyploids as Models in Evolutionary Studies; Introduction; Experimental Advantages of Budding Yeasts; Yeast Hybrids; Yeast Polyploids; Paleopolyploidy and Duplicated Genes Retention; Ploidy and Evolution-Theory and Experiments; Genomic Response to Polyploidy and Hybridity; Yeast Hybrids as a Tool for Studying Genomic Regulation; Conclusions; Acknowledgments; References
Chapter 2: Transcriptome Profiling of Drosophila Interspecific Hybrids: Insights into Mechanisms of Regulatory Divergence and Hybrid DysfunctionIntroduction; Gene Expression; Drosophila Hybrids as a Model to Study Transcriptome Divergence; Outlook; References; Chapter 3: cis- and trans-Regulation in Drosophila Interspecific Hybrids; Introduction; Distinguishing between cis- and trans-Regulatory Changes Using eQTL, GWAS, and ASE; Methods Used to Quantify ASE; Studies of cis- and trans-Regulation in Interspecific Hybrids of Drosophila; Insights into Regulatory Evolution
cis- and trans-Regulatory Evolution in Drosophila: A Look AheadReferences; Chapter 4: Gene Expression and Heterosis in Maize Hybrids; Introduction; Gene Expression in Maize Hybrids-Transcript Abundance Relative to Inbred Parents; Allele-Specific Gene Regulation in the Maize Hybrid; Modes of Gene Regulation in the Hybrid; Genetic and Structural Diversities That Contribute to Regulatory Variation; Understanding Heterosis-Various Models; Perspectives; Acknowledgments; References; Chapter 5: Integrating "Omics" Data and Expression QTL to Understand Maize Heterosis; Introduction
Experimental Design and eQTL AnalysiseQTL and the Mechanisms Underlying Gene Regulation; Building Networks and Integrating "omics" to Understand How Variants, in Particular eQTL, Can Result in Phenotypic Variation; Conclusion and Future Prospects; Acknowledgments; References; Chapter 6: Genomics and Heterosis in Hexaploid Wheat; Introduction; Genetic Dissection of Wheat Heterosis; Transcriptome and Proteome Analysis between Wheat Hybrids and Parents; Some Differentially Expressed Patterns are Correlated with Wheat Heterosis
Function Analysis of Differentially Expressed Genes between Wheat Hybrids and Their Parental LinesPossible Regulatory Mechanism Contributing to Differential Gene Expression in Wheat; Physiological Basis of Heterosis for Grain Yield in Wheat; Concluding Remarks; Acknowledgments; References; Chapter 7: Progress of Genomics and Heterosis Studies in Hybrid Rice; Introduction; Progress in the Study of Rice Genomics; Heterosis and Transcriptomics in Hybrid Rice; Epigenetic Modification and Heterosis in Hybrid Rice; Molecular Mechanism behind Heterosis; Perspectives; Acknowledgments; References
Chapter 8: Heterosis: The Case for Single-Gene Overdominance
Record Nr. UNINA-9910821352903321
Ames, Iowa, : Wiley-Blackwell, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Praise of chromosome "folly" [[electronic resource] ] : confessions of an untamed molecular structure / / Antonio Lima-de-Faria
Praise of chromosome "folly" [[electronic resource] ] : confessions of an untamed molecular structure / / Antonio Lima-de-Faria
Autore Lima-de-Faria A
Pubbl/distr/stampa Singapore ; ; Hackensack, NJ, : World Scientific, c2008
Descrizione fisica 1 online resource (428 p.)
Disciplina 572.8/7
Soggetto topico Chromosomes
Mutation (Biology)
Genetics
Soggetto genere / forma Electronic books.
ISBN 981-281-095-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto To the Reader; References; Contents; Introductory Note; Part I The Source of "Folly" and the Reason for Confessions; 1. I am an Inconspicuous and Unattractive Creature Painted with Lipstick; 2. They Say That I Resemble a Sausage; 3. The Cell Is My Castle and Prison But I May Swim and Dance like an Odalisque in a Harem; 4. The Striptease Show - How I Dress and Undress at Every Cell Division; 5. I Have Created My Own Private World Full of Tricks, Back Door Exits and Novel Solutions - I am an Untamed Innovator
6. My Origins Were Humble - The Antithetical Nature of Matter Left a Mark on My Construction7. My Split Personality - The Source of "Folly"; 8. The Reason for Confessions; 9. I Have Been Abused and Covered With Insults; 10. The Wisdom of the Foolish; 11. Scientific Concepts Are Prone to Change Throughout Time - The Nature of Science Demands that Previous Ideas be Superseded, as New TechnologiesAllow a Deeper Insight into Matter
12. What Seems Ludicrous at a Given Time Turns Out to be the Correct Explanation Several Years Later. The Gene was Considered to Consist of Protein, But Is Now Known to be a Ribbon of DNA13. In the Last 20 Years the Number of Human Genes was Reduced from 200,000 to 32,000, and This Figure Remains Uncertain; 14. The Models of Chromosomes Have Varied Drastically with Time; References; Sources of Illustrations; Part II Who Cares for Gravity; 15. The Chromosome in Its Organization and Activity Follows Its Own Path - It Does Not Obey Gravity, Randomness, Selection or Magnetism
16. Definition of Gravity - Newton's Laws Are Good for Planets and Apples17. What Is a Force - The Four Fundamental Forces; 18. Newton's Laws Do Not Apply in Quantum Mechanics; 19. Not All Bodies Fall When Unsupported; 20. The Ascent of Sap in Trees-Another Unexplained Phenomenon; 21. An Unknown Process Decides Which Cells Are Going to Grow in the Direction of Gravity and Which Are Going to Counteract It; 22. Physicists Construct Antigravity Devices that Oblige Frogs and Plants to Float
23. Atoms Hide Many Properties that May Disclose the Mechanisms Behind Living Processes - Liquid Helium Can Build a Fountain Ejecting Itself Out of a Flask24. Levitation in Metals - What Was Impossible Became Possible; 25. Animals, like Plants, Have Created Devices that Counteract Gravity; 26. In Giraffes the Distance between the Heart and the Head Is Over Two Meters; 27. No Chromosome Obeys Newton's Laws - In Their Movements Chromosomes Bypass Gravity; 28. Chromosomes Move in All Directions of the Mariner's Compass
29. It Is the Programmed Pattern of the Organism that Decides the Direction of Movement
Record Nr. UNINA-9910455037703321
Lima-de-Faria A  
Singapore ; ; Hackensack, NJ, : World Scientific, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Praise of chromosome "folly" [[electronic resource] ] : confessions of an untamed molecular structure / / Antonio Lima-de-Faria
Praise of chromosome "folly" [[electronic resource] ] : confessions of an untamed molecular structure / / Antonio Lima-de-Faria
Autore Lima-de-Faria A
Pubbl/distr/stampa Singapore ; ; Hackensack, NJ, : World Scientific, c2008
Descrizione fisica 1 online resource (428 p.)
Disciplina 572.8/7
Soggetto topico Chromosomes
Mutation (Biology)
Genetics
ISBN 981-281-095-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto To the Reader; References; Contents; Introductory Note; Part I The Source of "Folly" and the Reason for Confessions; 1. I am an Inconspicuous and Unattractive Creature Painted with Lipstick; 2. They Say That I Resemble a Sausage; 3. The Cell Is My Castle and Prison But I May Swim and Dance like an Odalisque in a Harem; 4. The Striptease Show - How I Dress and Undress at Every Cell Division; 5. I Have Created My Own Private World Full of Tricks, Back Door Exits and Novel Solutions - I am an Untamed Innovator
6. My Origins Were Humble - The Antithetical Nature of Matter Left a Mark on My Construction7. My Split Personality - The Source of "Folly"; 8. The Reason for Confessions; 9. I Have Been Abused and Covered With Insults; 10. The Wisdom of the Foolish; 11. Scientific Concepts Are Prone to Change Throughout Time - The Nature of Science Demands that Previous Ideas be Superseded, as New TechnologiesAllow a Deeper Insight into Matter
12. What Seems Ludicrous at a Given Time Turns Out to be the Correct Explanation Several Years Later. The Gene was Considered to Consist of Protein, But Is Now Known to be a Ribbon of DNA13. In the Last 20 Years the Number of Human Genes was Reduced from 200,000 to 32,000, and This Figure Remains Uncertain; 14. The Models of Chromosomes Have Varied Drastically with Time; References; Sources of Illustrations; Part II Who Cares for Gravity; 15. The Chromosome in Its Organization and Activity Follows Its Own Path - It Does Not Obey Gravity, Randomness, Selection or Magnetism
16. Definition of Gravity - Newton's Laws Are Good for Planets and Apples17. What Is a Force - The Four Fundamental Forces; 18. Newton's Laws Do Not Apply in Quantum Mechanics; 19. Not All Bodies Fall When Unsupported; 20. The Ascent of Sap in Trees-Another Unexplained Phenomenon; 21. An Unknown Process Decides Which Cells Are Going to Grow in the Direction of Gravity and Which Are Going to Counteract It; 22. Physicists Construct Antigravity Devices that Oblige Frogs and Plants to Float
23. Atoms Hide Many Properties that May Disclose the Mechanisms Behind Living Processes - Liquid Helium Can Build a Fountain Ejecting Itself Out of a Flask24. Levitation in Metals - What Was Impossible Became Possible; 25. Animals, like Plants, Have Created Devices that Counteract Gravity; 26. In Giraffes the Distance between the Heart and the Head Is Over Two Meters; 27. No Chromosome Obeys Newton's Laws - In Their Movements Chromosomes Bypass Gravity; 28. Chromosomes Move in All Directions of the Mariner's Compass
29. It Is the Programmed Pattern of the Organism that Decides the Direction of Movement
Record Nr. UNINA-9910778073903321
Lima-de-Faria A  
Singapore ; ; Hackensack, NJ, : World Scientific, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor
Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor
Pubbl/distr/stampa New York, : Nova Biomedical Books, c2009
Descrizione fisica 1 online resource (498 p.)
Disciplina 572.8/7
Altri autori (Persone) ManciniLeonardo
Soggetto topico Telomere
Telomerase
Soggetto genere / forma Electronic books.
ISBN 1-60876-720-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910452470603321
New York, : Nova Biomedical Books, c2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor
Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor
Pubbl/distr/stampa New York, : Nova Biomedical Books, c2009
Descrizione fisica 1 online resource (498 p.)
Disciplina 572.8/7
Altri autori (Persone) ManciniLeonardo
Soggetto topico Telomere
Telomerase
ISBN 1-60876-720-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Telomere dynamics and biology in human progeroid syndromes / Terence Davis, Hannah S.E. Tivey, and David Kipling -- The role of telomere-telomerase system in age-related fitness decline : a tameable process / Giacinto Libertini -- Cytogenetic evaluation of telomere dysfunction : chromosomal aberrations involving telomeres and interstitial telomeric sequences / Alejandro D. Bolzán -- Telomeres-telomerase biology and their role in renal and other chronic diseases / Kordinas Vasileios ... [et al.] -- Telomerase and telomere dynamics in cancer : clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama -- Telomeres and chromosome segregation / Antonella Sgura and Daniela Cimini -- Telomere-based genome-protective responses : a mammalian improvement on the bacterial SOS response? / Barbara A. Gilchrest, Mark S. Eller -- Telomere lengthening from oocyte to embryonic stem cell / Eva Pericuesta ... [et al.] -- Transcriptional activity at the telomeres of chironomus (diptera) : its possible role in the lengthening of the telomeres / J.L. Diez ... [et al.] --
Telomerase activity : application to diagnosis of human carcinoma / Liliana N. Guerra -- Telomere shortening in diabetes mellitus / Nicholas Tentolouris, Athanasia Papazafiropoulou -- Do alterations in the three-dimensional organization of telomeres indicate malignant transformation? / Sandrine Lacoste, Hans Knecht, and Sabine Mai -- Telomeres : function, shortening and lengthening / Barry Flanary -- Telomerase regulation in stem cells : how to flip the switch? / Rich Allsopp -- Telomere maintenance mechanisms in bone and soft tissue tumors / Toshihiro Matsuo ... [et al.] -- Genetic polymorphisms of human telomerase reverse transcriptase (hTERT) : mini review / Yumiko Matsubara, Mitsuru Murata, and Yasuo Ikeda -- Genetic inhibition of telomere lengthening in cancer prevention and treatment / F. Mathias Bollmann -- Telomeres : function, shortening, and lengthening / Barry Flanary -- Clinical implications of telomerase activity in human brain tumors / Hyoung-Joon Chun ... [et al.].
Record Nr. UNINA-9910779646103321
New York, : Nova Biomedical Books, c2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui