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Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Pubbl/distr/stampa Weinheim ; ; New York, : Wiley-VCH, c2003
Descrizione fisica 1 online resource (984 p.)
Disciplina 572.8/65
572.865
Altri autori (Persone) LorkowskiStefan
CullenPaul, Dr.
Soggetto topico Gene expression
Soggetto genere / forma Electronic books.
ISBN 1-280-52042-6
9786610520428
3-527-60533-9
3-527-60149-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Analysing Gene Expression A Handbook of Methods Possibilities and Pitfalls; Foreword; Preface; Contents; List of Contributors; Volume 1; 1 Basic concepts of gene expression; 1.1 Introduction; 1.2 Basics of transcription and translation in the cell; 1.2.1 Introduction; 1.2.2 Transcription; 1.2.3 Translation; 1.2.4 Summary; 1.3 Regulation of transcription; 1.3.1 Introduction; 1.3.2 mRNA expression profiles - the transcriptome; 1.3.3 Protein expression profiles - the proteome; 1.3.4 Interaction between genes and proteins - the interactome; 1.3.5 The transcription machinery and core promoters
1.3.6 Regulatory promoters1.3.7 Enhancers; 1.3.8 Locus control regions; 1.3.9 Matrix attachment regions; 1.3.10 Insulators; 1.3.11 RIDGEs - Regions of increased gene expression; 1.3.12 Enhanceosomes; 1.3.13 Chromatin; 1.3.14 Silencer elements; 1.3.15 Transcription factors, repressors and co-repressors; 1.3.16 Epigenetics; 1.3.17 Summary and conclusions; 1.4 Post-transcriptional regulation; 1.4.1 Introduction; 1.4.2 Regulation of RNA stability and degradation; 1.4.3 Regulation of transcription elongation; 1.4.3.1 Introduction; 1.4.3.2 Regulation of transcription elongation in prokaryotes
1.4.3.3 Regulation of transcription elongation in eukaryotes1.4.3.4 Conclusions; 1.4.4 Differential/alternative pre-mRNA splicing; 1.4.5 Trans-RNA splicing; 1.4.6 Regulation of mRNA transport; 1.4.7 Directed intracellular mRNA localisation; 1.4.8 Regulation of mRNA polyadenylation; 1.4.9 Antisense RNA; 1.4.10 RNA editing; 1.4.11 Summary and conclusions; 1.5 Post-translational modification of proteins; 1.5.1 Introduction; 1.5.2 Proteolytic cleavage of proteins; 1.5.3 Acylation; 1.5.4 Prenylation; 1.5.5 Methylation; 1.5.6 Sulphation; 1.5.7 Phosphorylation; 1.5.8 Ubiquitination
1.5.9 Glycosylation1.5.10 Conclusions; 1.6 Correlation of mRNA and protein expression; 1.6.1 Introduction; 1.6.2 Levels of mRNA and protein expression: correlations and discrepancies; 1.6.3 Conclusions; 1.7 Housekeeping genes, internal and external standards; 1.7.1 What are housekeeping genes?; 1.7.2 Survey of the most important housekeeping genes; 1.7.2.1 Glyceraldehyde-3-phosphate dehydrogenase; 1.7.2.2 β-Actin; 1.7.3 Other commonly used housekeeping genes; 1.7.3.1 Ribosomal RNA (rRNA); 1.7.4 New identified 'maintenance genes'; 1.7.5 Methods of quantification
1.7.5.1 Normalisation (via internal standards)1.7.5.2 Standard curves (via external standards); 1.7.5.3 Alternative methods (via internal standards); 1.7.6 Summary; 1.8 Classification of differential gene expression technologies; 1.8.1 Introduction; 1.8.2 From single genes to transcriptomes; 1.8.3 Methods of classification; 1.8.4 Conclusions; 1.9 Summary; 1.10 References; 2 Sample preparation and supplementary tools; 2.1 Introduction; 2.2 Preparation of cells and tissues; 2.2.1 Immunopurification of cells; 2.2.2 Differential-velocity centrifugation/countercurrent elutriation
2.2.3 Surface affinity chromatography
Record Nr. UNINA-9910146242103321
Weinheim ; ; New York, : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Pubbl/distr/stampa Weinheim ; ; New York, : Wiley-VCH, c2003
Descrizione fisica 1 online resource (984 p.)
Disciplina 572.8/65
572.865
Altri autori (Persone) LorkowskiStefan
CullenPaul, Dr.
Soggetto topico Gene expression
ISBN 1-280-52042-6
9786610520428
3-527-60533-9
3-527-60149-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Analysing Gene Expression A Handbook of Methods Possibilities and Pitfalls; Foreword; Preface; Contents; List of Contributors; Volume 1; 1 Basic concepts of gene expression; 1.1 Introduction; 1.2 Basics of transcription and translation in the cell; 1.2.1 Introduction; 1.2.2 Transcription; 1.2.3 Translation; 1.2.4 Summary; 1.3 Regulation of transcription; 1.3.1 Introduction; 1.3.2 mRNA expression profiles - the transcriptome; 1.3.3 Protein expression profiles - the proteome; 1.3.4 Interaction between genes and proteins - the interactome; 1.3.5 The transcription machinery and core promoters
1.3.6 Regulatory promoters1.3.7 Enhancers; 1.3.8 Locus control regions; 1.3.9 Matrix attachment regions; 1.3.10 Insulators; 1.3.11 RIDGEs - Regions of increased gene expression; 1.3.12 Enhanceosomes; 1.3.13 Chromatin; 1.3.14 Silencer elements; 1.3.15 Transcription factors, repressors and co-repressors; 1.3.16 Epigenetics; 1.3.17 Summary and conclusions; 1.4 Post-transcriptional regulation; 1.4.1 Introduction; 1.4.2 Regulation of RNA stability and degradation; 1.4.3 Regulation of transcription elongation; 1.4.3.1 Introduction; 1.4.3.2 Regulation of transcription elongation in prokaryotes
1.4.3.3 Regulation of transcription elongation in eukaryotes1.4.3.4 Conclusions; 1.4.4 Differential/alternative pre-mRNA splicing; 1.4.5 Trans-RNA splicing; 1.4.6 Regulation of mRNA transport; 1.4.7 Directed intracellular mRNA localisation; 1.4.8 Regulation of mRNA polyadenylation; 1.4.9 Antisense RNA; 1.4.10 RNA editing; 1.4.11 Summary and conclusions; 1.5 Post-translational modification of proteins; 1.5.1 Introduction; 1.5.2 Proteolytic cleavage of proteins; 1.5.3 Acylation; 1.5.4 Prenylation; 1.5.5 Methylation; 1.5.6 Sulphation; 1.5.7 Phosphorylation; 1.5.8 Ubiquitination
1.5.9 Glycosylation1.5.10 Conclusions; 1.6 Correlation of mRNA and protein expression; 1.6.1 Introduction; 1.6.2 Levels of mRNA and protein expression: correlations and discrepancies; 1.6.3 Conclusions; 1.7 Housekeeping genes, internal and external standards; 1.7.1 What are housekeeping genes?; 1.7.2 Survey of the most important housekeeping genes; 1.7.2.1 Glyceraldehyde-3-phosphate dehydrogenase; 1.7.2.2 β-Actin; 1.7.3 Other commonly used housekeeping genes; 1.7.3.1 Ribosomal RNA (rRNA); 1.7.4 New identified 'maintenance genes'; 1.7.5 Methods of quantification
1.7.5.1 Normalisation (via internal standards)1.7.5.2 Standard curves (via external standards); 1.7.5.3 Alternative methods (via internal standards); 1.7.6 Summary; 1.8 Classification of differential gene expression technologies; 1.8.1 Introduction; 1.8.2 From single genes to transcriptomes; 1.8.3 Methods of classification; 1.8.4 Conclusions; 1.9 Summary; 1.10 References; 2 Sample preparation and supplementary tools; 2.1 Introduction; 2.2 Preparation of cells and tissues; 2.2.1 Immunopurification of cells; 2.2.2 Differential-velocity centrifugation/countercurrent elutriation
2.2.3 Surface affinity chromatography
Record Nr. UNINA-9910830158703321
Weinheim ; ; New York, : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Pubbl/distr/stampa Weinheim ; ; New York, : Wiley-VCH, c2003
Descrizione fisica 1 online resource (984 p.)
Disciplina 572.8/65
572.865
Altri autori (Persone) LorkowskiStefan
CullenPaul, Dr.
Soggetto topico Gene expression
ISBN 1-280-52042-6
9786610520428
3-527-60533-9
3-527-60149-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Analysing Gene Expression A Handbook of Methods Possibilities and Pitfalls; Foreword; Preface; Contents; List of Contributors; Volume 1; 1 Basic concepts of gene expression; 1.1 Introduction; 1.2 Basics of transcription and translation in the cell; 1.2.1 Introduction; 1.2.2 Transcription; 1.2.3 Translation; 1.2.4 Summary; 1.3 Regulation of transcription; 1.3.1 Introduction; 1.3.2 mRNA expression profiles - the transcriptome; 1.3.3 Protein expression profiles - the proteome; 1.3.4 Interaction between genes and proteins - the interactome; 1.3.5 The transcription machinery and core promoters
1.3.6 Regulatory promoters1.3.7 Enhancers; 1.3.8 Locus control regions; 1.3.9 Matrix attachment regions; 1.3.10 Insulators; 1.3.11 RIDGEs - Regions of increased gene expression; 1.3.12 Enhanceosomes; 1.3.13 Chromatin; 1.3.14 Silencer elements; 1.3.15 Transcription factors, repressors and co-repressors; 1.3.16 Epigenetics; 1.3.17 Summary and conclusions; 1.4 Post-transcriptional regulation; 1.4.1 Introduction; 1.4.2 Regulation of RNA stability and degradation; 1.4.3 Regulation of transcription elongation; 1.4.3.1 Introduction; 1.4.3.2 Regulation of transcription elongation in prokaryotes
1.4.3.3 Regulation of transcription elongation in eukaryotes1.4.3.4 Conclusions; 1.4.4 Differential/alternative pre-mRNA splicing; 1.4.5 Trans-RNA splicing; 1.4.6 Regulation of mRNA transport; 1.4.7 Directed intracellular mRNA localisation; 1.4.8 Regulation of mRNA polyadenylation; 1.4.9 Antisense RNA; 1.4.10 RNA editing; 1.4.11 Summary and conclusions; 1.5 Post-translational modification of proteins; 1.5.1 Introduction; 1.5.2 Proteolytic cleavage of proteins; 1.5.3 Acylation; 1.5.4 Prenylation; 1.5.5 Methylation; 1.5.6 Sulphation; 1.5.7 Phosphorylation; 1.5.8 Ubiquitination
1.5.9 Glycosylation1.5.10 Conclusions; 1.6 Correlation of mRNA and protein expression; 1.6.1 Introduction; 1.6.2 Levels of mRNA and protein expression: correlations and discrepancies; 1.6.3 Conclusions; 1.7 Housekeeping genes, internal and external standards; 1.7.1 What are housekeeping genes?; 1.7.2 Survey of the most important housekeeping genes; 1.7.2.1 Glyceraldehyde-3-phosphate dehydrogenase; 1.7.2.2 β-Actin; 1.7.3 Other commonly used housekeeping genes; 1.7.3.1 Ribosomal RNA (rRNA); 1.7.4 New identified 'maintenance genes'; 1.7.5 Methods of quantification
1.7.5.1 Normalisation (via internal standards)1.7.5.2 Standard curves (via external standards); 1.7.5.3 Alternative methods (via internal standards); 1.7.6 Summary; 1.8 Classification of differential gene expression technologies; 1.8.1 Introduction; 1.8.2 From single genes to transcriptomes; 1.8.3 Methods of classification; 1.8.4 Conclusions; 1.9 Summary; 1.10 References; 2 Sample preparation and supplementary tools; 2.1 Introduction; 2.2 Preparation of cells and tissues; 2.2.1 Immunopurification of cells; 2.2.2 Differential-velocity centrifugation/countercurrent elutriation
2.2.3 Surface affinity chromatography
Record Nr. UNINA-9910841895203321
Weinheim ; ; New York, : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]]
DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]]
Autore Baldi Pierre
Pubbl/distr/stampa Cambridge : , : Cambridge University Press, , 2002
Descrizione fisica 1 online resource (xvi, 213 pages) : digital, PDF file(s)
Disciplina 572.8/65
Soggetto topico DNA microarrays
Gene expression
ISBN 1-107-13017-4
1-280-16041-1
9786610160419
0-511-06321-0
0-511-11922-4
1-139-14694-7
0-511-05688-5
0-511-32267-4
0-511-54177-5
0-511-07167-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction,clustering,and regulatory regions; 7 The design, analysis,and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index
Altri titoli varianti DNA Microarrays & Gene Expression
Record Nr. UNINA-9910450497003321
Baldi Pierre  
Cambridge : , : Cambridge University Press, , 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]]
DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]]
Autore Baldi Pierre
Pubbl/distr/stampa Cambridge : , : Cambridge University Press, , 2002
Descrizione fisica 1 online resource (xvi, 213 pages) : digital, PDF file(s)
Disciplina 572.8/65
Soggetto topico DNA microarrays
Gene expression
ISBN 1-107-13017-4
1-280-16041-1
9786610160419
0-511-06321-0
0-511-11922-4
1-139-14694-7
0-511-05688-5
0-511-32267-4
0-511-54177-5
0-511-07167-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction,clustering,and regulatory regions; 7 The design, analysis,and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index
Altri titoli varianti DNA Microarrays & Gene Expression
Record Nr. UNINA-9910783118803321
Baldi Pierre  
Cambridge : , : Cambridge University Press, , 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]]
DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]]
Autore Baldi Pierre
Pubbl/distr/stampa Cambridge : , : Cambridge University Press, , 2002
Descrizione fisica 1 online resource (xvi, 213 pages) : digital, PDF file(s)
Disciplina 572.8/65
Soggetto topico DNA microarrays
Gene expression
ISBN 1-107-13017-4
1-280-16041-1
9786610160419
0-511-06321-0
0-511-11922-4
1-139-14694-7
0-511-05688-5
0-511-32267-4
0-511-54177-5
0-511-07167-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction,clustering,and regulatory regions; 7 The design, analysis,and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index
Altri titoli varianti DNA Microarrays & Gene Expression
Record Nr. UNINA-9910829175403321
Baldi Pierre  
Cambridge : , : Cambridge University Press, , 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Genes and Signals [[electronic resource]]
Genes and Signals [[electronic resource]]
Autore Ptashne Mark
Pubbl/distr/stampa Woodbury, NY, USA, : Cold Spring Harbor Laboratory Press, 20011201
Descrizione fisica 1 online resource (209 p.)
Disciplina 572.8/65
Soggetto topico SCIENCE
Life Sciences / Genetics & Genomics
Genetic regulation
Genetics
Biology
Health & Biological Sciences
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910450575903321
Ptashne Mark  
Woodbury, NY, USA, : Cold Spring Harbor Laboratory Press, 20011201
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Genes and Signals [[electronic resource]]
Genes and Signals [[electronic resource]]
Autore Ptashne Mark
Pubbl/distr/stampa Woodbury, NY, USA, : Cold Spring Harbor Laboratory Press, 20011201
Descrizione fisica 1 online resource (209 p.)
Disciplina 572.8/65
Soggetto topico SCIENCE
Life Sciences / Genetics & Genomics
Genetic regulation
Genetics
Biology
Health & Biological Sciences
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910783248503321
Ptashne Mark  
Woodbury, NY, USA, : Cold Spring Harbor Laboratory Press, 20011201
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Genes and Signals [[electronic resource]]
Genes and Signals [[electronic resource]]
Autore Ptashne Mark
Pubbl/distr/stampa Woodbury, NY, USA, : Cold Spring Harbor Laboratory Press, 20011201
Descrizione fisica 1 online resource (209 p.)
Disciplina 572.8/65
Soggetto topico SCIENCE
Life Sciences / Genetics & Genomics
Genetic regulation
Genetics
Biology
Health & Biological Sciences
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910807706503321
Ptashne Mark  
Woodbury, NY, USA, : Cold Spring Harbor Laboratory Press, 20011201
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Genomic signal processing / / Ilya Shmulevich and Edward R. Dougherty
Genomic signal processing / / Ilya Shmulevich and Edward R. Dougherty
Autore Shmulevich Ilya <1969->
Pubbl/distr/stampa Princeton, New Jersey ; ; Oxfordshire, England : , : Princeton University Press, , 2007
Descrizione fisica 1 online resource (314 p.)
Disciplina 572.8/65
Collana Princeton Series in Applied Mathematics
Soggetto topico Cellular signal transduction
Genetic regulation
Genomics - Mathematical models
Gene regulatory networks
Soggetto genere / forma Electronic books.
ISBN 1-4008-6526-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front matter -- Contents -- Preface -- Chapter One. Biological Foundations -- Chapter Two. Deterministic Models of Gene Networks -- Chapter Three. Stochastic Models of Gene Networks -- Chapter Four. Classification -- Chapter Five. Regularization -- Chapter Six. Clustering -- Index
Record Nr. UNINA-9910465346503321
Shmulevich Ilya <1969->  
Princeton, New Jersey ; ; Oxfordshire, England : , : Princeton University Press, , 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui