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AMP-activated Protein Kinase / / edited by Mario D. Cordero, Benoit Viollet
AMP-activated Protein Kinase / / edited by Mario D. Cordero, Benoit Viollet
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (X, 523 p. 55 illus., 42 illus. in color.)
Disciplina 572.792
Collana Experientia Supplementum
Soggetto topico Human physiology
Medical biochemistry
Metabolic diseases
Human Physiology
Medical Biochemistry
Metabolic Diseases
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I: AMPK in health -- Structure and Regulation of AMPK -- AMPK Regulation of Carbohydrate Metabolism -- AMPK Regulation of Lipid Metabolism -- AMPK Regulation of Protein Metabolism -- AMPK Regulation of cell growth, apoptosis, autophagy and bioenergetics -- AMPK Regulation of immunology -- AMPK and Stem Cells -- Part II: AMPK in the diseases -- AMPK in metabolic diseases -- AMPK in neurodegenerative diseases -- AMPK in cardiovascular diseases -- AMPK in cancer -- AMPK in aging -- AMPK in musculoskeletal diseases and pain -- AMPK in pathogens -- Part III: Pharmacology of AMPK -- Metformin, new drugs and AMPK -- Small molecules and AMPK -- Nutraceutical compounds and AMPK -- Part IV: Methods of study in AMPK -- Animal models -- In vitro study methods.
Record Nr. UNINA-9910149489103321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
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Next Generation Kinase Inhibitors : Moving Beyond the ATP Binding/Catalytic Sites / / edited by Paul Shapiro
Next Generation Kinase Inhibitors : Moving Beyond the ATP Binding/Catalytic Sites / / edited by Paul Shapiro
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (XII, 217 p. 59 illus., 56 illus. in color.)
Disciplina 572.792
Soggetto topico Cancer research
Cancer Research
Proteïnes quinases
Soggetto genere / forma Llibres electrònics
ISBN 3-030-48283-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1: Introduction to Kinases, Cellular Signaling, and Kinase Inhibitors -- Chapter 2: Overview of Current Type I/II Kinase Inhibitors -- Chapter 3: Avoiding or Co-opting ATP Inhibition: Type III, IV, V, and VI Kinase Inhibitors -- Chapter 4: Structural Features Regulating Kinase Interactions with Regulatory and Substrate Proteins -- Chapter 5: Developing Kinase Inhibitors using Computer-Aided Drug Design Approaches -- Chapter 6: A Toolbox of Structural Biology and Enzyme Kinetics Reveals the Case for ERK Docking Site Inhibition -- Chapter 7: Novel Stabilized Peptide Inhibitors of Protein Kinases -- Chapter 8: Novel peptide-based inhibitors of protein kinases -- Index.
Record Nr. UNINA-9910416107703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
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Proteinkinase inhibitors / / Stefan Laufer, Editor
Proteinkinase inhibitors / / Stefan Laufer, Editor
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (259 pages) : illustrations
Disciplina 572.792
Collana Topics in Medicinal Chemistry
Soggetto topico Bioorganic chemistry
Proteins
Pharmaceutical chemistry
ISBN 3-030-68180-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910483133403321
Cham, Switzerland : , : Springer, , [2021]
Materiale a stampa
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Springer handbook of enzymes . Supplement, Volume S9 Class 2-3.2 transferases, hydrolases : EC 2-3.2 / / Dietmar Schomburg, Ida Schomburg (eds.); co-edited by Antje Chang
Springer handbook of enzymes . Supplement, Volume S9 Class 2-3.2 transferases, hydrolases : EC 2-3.2 / / Dietmar Schomburg, Ida Schomburg (eds.); co-edited by Antje Chang
Edizione [2nd ed.]
Pubbl/distr/stampa Berlin ; ; Heidleberg, : Springer-Verlag, 2013
Descrizione fisica 1 online resource (698 p.)
Disciplina 572.7
572.792
572/.792
Altri autori (Persone) SchomburgD (Dietmar)
SchomburgIda <1954->
ChangAntje
Collana Springer Handbook of Enzymes
Soggetto topico Transferases
Hydrolases
ISBN 3-642-36240-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 2.1.1.163 demethylmenaquinone methyltransferase -- 2.1.1.164 demethylrebeccamycin-D-glucose Omethyltransferase -- 2.1.1.165 methyl halide transferase -- 2.1.1.166 23S rRNA (uridine2552-2’-O-)-methyltransferase -- 2.1.1.167 27S pre-rRNA (guanosine2922-2’-O)-methyltransferase -- 2.1.1.168 21S rRNA (uridine2791-2’-O)-methyltransferase -- 2.1.1.169 tricetin 3’,4’,5’-O-trimethyltransferase -- 2.1.1.170 16S rRNA (guanine527-N7)-methyltransferase -- 2.1.1.171 16S rRNA (guanine966-N2)-methyltransferase -- 2.1.1.172 16S rRNA (guanine1207-N2)-methyltransferase -- 2.1.1.173 23S rRNA (guanine2445-N2)-methyltransferase -- 2.1.1.174 23S rRNA (guanine1835-N2)-methyltransferase -- 2.1.1.175 tricin synthase -- 2.1.1.176 16S rRNA (cytosine967-C5)-methyltransferase -- 2.1.1.177 23S rRNA (pseudouridine1915-N3)-methyltransferase -- 2.1.1.178 16S rRNA (cytosine1407-C5)-methyltransferase -- 2.1.1.179 16S rRNA (guanine1405-N7)-methyltransferase -- 2.1.1.180 16S rRNA (adenine1408-N1)-methyltransferase -- 2.1.1.181 23S rRNA (adenine1618-N6)-methyltransferase -- 2.1.1.182 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase -- 2.1.1.183 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase -- 2.1.1.184 23S rRNA (adenine2085-N6)- dimethyltransferase -- 2.1.1.185 23S rRNA (guanosine2251-2’-O-)- methyltransferase -- 2.1.1.186 23S rRNA (cytidine2498-2’-O)-methyltransferase -- 2.1.1.195 cobalt-precorrin-5B (C1)-methyltransferase -- 2.1.1.196 cobalt-precorrin-7 (C15)-methyltransferase[decarboxylating] -- 2.1.1.197 malonyl-CoA O-methyltransferase -- 2.1.1.198 16S rRNA (cytidine1402-2’-O)-methyltransferase -- 2.1.1.199 16S rRNA (cytosine1402-N4)-methyltransferase -- 2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase -- 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase:- 2.1.3.11 N-succinylornithine carbamoyltransferase -- 2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase -- 2.3.1.185 tropine acyltransferase -- 2.3.1.186 pseudotropine acyltransferase -- 2.3.1.187 acetyl-S-ACP:malonate ACP transferase -- 2.3.1.188 w-hydroxypalmitate O-feruloyl transferase -- 2.3.1.189 mycothiol synthase -- 2.3.1.190 acetoin dehydrogenase -- 2.3.1.191 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase -- 2.3.1.192 glycine N-phenylacetyltransferase -- 2.3.2.16 lipid II:glycine glycyltransferase -- 2.3.2.17 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl- (N6-glycyl)-D-alanyl-D-alaninediphosphoundecaprenyl-Nacetylglucosamine: glycine glycyltransferase -- 2.3.2.18 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl- (N6-triglycine)-D-alanyl-D-alaninediphosphoundecaprenyl-Nacetylglucosamine: glycine lycyltransferase -- 2.4.1.245 a,a-trehalose synthase -- 2.4.1.247 b-D-galactosyl-(1!4)-L-rhamnose phosphorylase -- 2.4.1.248 cycloisomaltooligosaccharide glucanotransferase -- 2.4.1.249 delphinidin 3’,5’-O-glucosyltransferase -- 2.4.1.250 D-inositol-3-phosphate glycosyltransferase -- 2.4.1.251 GlcA-b-(1!2)-D-Man-a-(1!3)-D-Glc-b- (1!4)-D-Glc-a-1-diphospho-ditrans,octacisundecaprenol 4-b-mannosyltransferase -- 2.4.1.252 GDP-mannose:cellobiosyldiphosphopolyprenol a-mannosyltransferase -- 2.4.1.253 baicalein 7-O-glucuronosyltransferase -- 2.4.2.41 xylogalacturonan b-1,3-xylosyltransferase -- 2.4.2.42 UDP-D-xylose:b-D-glucoside a-1,3-Dxylosyltransferase -- 2.4.2.43 lipid IVA 4-amino-4-deoxy-Larabinosyltransferase -- 2.4.99.12 lipid IVA 3-deoxy-D-manno-octulosonic acid transferase -- 2.4.99.13 (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase -- 2.4.99.14 (KDO)2-lipid IVA (2-8) 3-deoxy-D-mannooctulosonic acid transferase -- 2.4.99.15 (KDO)3-lipid IVA (2-4) 3-deoxy-D-mannooctulosonic acid transferase -- 2.5.1.72 quinolinate synthase -- 2.5.1.73 O-phospho-L-seryl-tRNA:Cys-tRNA synthase -- 2.5.1.74 1,4-dihydroxy-2-naphthoate polyprenyltransferase -- 2.5.1.75 tRNA dimethylallyltransferase -- 2.5.1.76 cysteate synthase -- 2.5.1.77 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase -- 2.5.1.78 6,7-dimethyl-8-ribityllumazine synthase -- 2.5.1.79 thermospermine synthase -- 2.5.1.80 7-dimethylallyltryptophan synthase -- 2.5.1.81 geranylfarnesyl diphosphate synthase -- 2.5.1.82 hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] -- 2.5.1.83 hexaprenyl-diphosphate synthase [(2E,6E)- farnesyl-diphosphate specific] -- 2.5.1.84 all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific] -- 2.5.1.85 all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] -- 2.5.1.86 trans,polycis-decaprenyl diphosphate Synthase -- 2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] -- 2.5.1.88 trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] -- 2.5.1.89 tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] -- 2.5.1.93 4-hydroxybenzoate geranyltransferase -- 2.5.1.94 adenosyl-chloride synthase -- 2.6.1.86 2-amino-4-deoxychorismate synthase -- 2.6.1.87 UDP-4-amino-4-deoxy-L-arabinose aminotransferase -- 2.7.1.161 CTP-dependent riboflavin kinase -- 2.7.1.162 N-acetylhexosamine 1-kinase -- 2.7.1.163 hygromycin B 4-O-kinase -- 2.7.1.164 O-phosphoseryl-tRNASec kinase -- 2.7.1.165 glycerate 2-kinase -- 2.7.1.166 3-deoxy-D-manno-octulosonic acid kinase -- 2.7.1.167 D-glycero-b-D-manno-heptose-7-phosphate kinase -- 2.7.1.168 D-glycero-a-D-manno-heptose-7-phosphate kinase -- 2.7.1.169 pantoate kinase -- 2.7.4.25 (d)CMP kinase -- 2.7.7.66 malonate decarboxylase holo-[acyl-carrier protein] synthase -- 2.7.7.67 CDP-archaeol synthase -- 2.7.7.68 2-phospho-L-lactate guanylyltransferase -- 2.7.7.70 D-glycero-b-D-manno-heptose 1-phosphate adenylyltransferase -- 2.7.7.71 D-glycero-a-D-manno-heptose 1-phosphate guanylyltransferase -- 2.7.7.72 CCA tRNA nucleotidyltransferase -- 2.7.8.28 2-phospho-L-lactate transferase -- 2.7.8.29 L-serine-phosphatidylethanolamine phosphatidyltransferase -- 2.7.8.30 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase -- 2.7.8.31 undecaprenyl-phosphate glucose phosphotransferase -- 2.8.2.35 dermatan 4-sulfotransferase -- 2.8.4.2 arsenate-mycothiol transferase -- 2.9.1.2 O-phospho-L-seryl-tRNASec:L-selenocysteinyltRNA synthase -- 3.1.1.83 monoterpene e-lactone hydrolase -- 3.1.1.84 cocaine esterase -- 3.1.2.28 1,4-dihydroxy-2-naphthoyl-CoA hydrolase -- 3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase -- 3.1.3.80 2,3-bisphosphoglycerate 3-phosphatase -- 3.1.3.81 diacylglycerol diphosphate phosphatase -- 3.1.3.82 -glycero-b-D-manno-heptose 1,7-bisphosphate 7-phosphatase -- 3.1.3.83 D-glycero-a-D-manno-heptose 1,7-bisphosphate 7-phosphatase -- 3.1.4.53 3’,5’-cyclic-AMP phosphodiesterase -- 3.1.7.4 sclareol cyclase -- 3.1.7.5 geranylgeranyl diphosphate diphosphatase -- 3.1.7.6 farnesyl diphosphatase -- 3.1.26.12 ribonuclease E -- 3.1.26.13 retroviral ribonuclease H -- 3.2.1.165 exo-1,4-b-D-glucosaminidase -- 3.2.1.167 baicalin-b-D-glucuronidase -- 3.2.1.168 hesperidin 6-O-a-L-rhamnosyl-b-Dglucosidase -- 3.2.2.27 uracil-DNA glycosylase -- 3.2.2.28 double-stranded uracil-DNA glycosylase -- 3.2.2.29 thymine-DNA glycosylase.
Record Nr. UNINA-9910437616803321
Berlin ; ; Heidleberg, : Springer-Verlag, 2013
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