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Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle
Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle
Edizione [2nd ed.]
Pubbl/distr/stampa Chichester ; ; Hoboken, NJ, : Wiley, c2004
Descrizione fisica 1 online resource (277 p.)
Disciplina 572.43
572.436
Altri autori (Persone) LadburyJohn E. <1960->
DoyleMichael L. <1959->
Soggetto topico Calorimetry
Biology - Technique
Soggetto genere / forma Electronic books.
ISBN 1-280-27608-8
9786610276080
0-470-01112-2
0-470-01111-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Biocalorimetry 2; Contents; Preface; List of Contributors; Part I General Introduction; 1 Applications of Biocalorimetry: Binding, Stability and Enzyme Kinetics; 1.1 Introduction; 1.2 Principles of isothermal titration calorimetry (ITC); 1.3 Applications of ITC in the life sciences; 1.4 Thermodynamic signatures of non-covalent interactions; 1.5 Thermodynamic discrimination (TD); 1.6 ITC as a tool for studying drug-DNA interactions; 1.7 ITC as a tool for studying protein-DNA interactions; 1.8 The application of calorimetry for examining hydration effcts
1.9 The use of ITC for studying the kinetics and thermodynamics of enzyme catalysis1.10 Principles of differential scanning calorimetry (DSC); 1.11 Applications of DSC in the life sciences; 1.12 Thermodynamic stability; 1.13 Shelf life versus thermodynamic stability; 1.14 Specific and non-specific binding; 1.15 Intrinsic and extrinsic macromolecular stability; 1.16 Oligomerization; 1.17 The use of DSC for examining nucleic acid helix coil transitions; 1.18 Summary; Acknowledgements; References; Part II Isothermal Titration Calorimetry; 2 Isothermal Titration Calorimetry: A Tutorial
2.1 Introduction2.2 Thermodynamic characterization; 2.3 Instrumentation; 2.4 Raw data; 2.5 Basic considerations for experimental set-up; 2.6 Data analysis; 2.7 Summary; Application notes; Acknowledgement; References; 3 The Application of Isothermal Titration Calorimetry to Drug Discovery; 3.1 Introduction; 3.2 Overview of the drug discovery process; 3.3 Experimental measurement of thermodynamic binding parameters; 3.4 ITC in drug discovery; 3.5 Summary; References; 4 Dissecting the Thermodynamics of DNA-Protein Interactions; 4.1 Introduction; 4.2 Model systems
4.3 Comparison with the hydrophobic effect4.4 Protonation and charged-charged hydrogen bonds; 4.5 Dissection of the binding entropy; 4.6 Entropy contributions to the Sso7d-DNA interaction; 4.7 Entropy contributions to the GCN4-DNA interaction; 4.8 Discussion; Acknowledgements; References; 5 Salt Effects in Ribonuclease-Ligand Interactions: Screening or Competitive Binding?; 5.1 Introduction; 5.2 Anion binding to a protein-protein complex; 5.3 Charge-charge interactions in ribonuclease binding; 5.4 Conclusions; Acknowledgement; References
6 Thermodynamics-Structure Correlations of Sulfonamide Inhibitor Binding to Carbonic Anhydrase6.1 Introduction; 6.2 Identification of protonation reactions occurring upon binding; 6.3 Observed thermodynamics of inhibitor binding to CA; 6.4 Energetics of inhibitor protonation; 6.5 Sulfonamide 'anion' binding thermodynamics; 6.6 Correlations between structures and the thermodynamics of sulfonamide binding to CA; 6.7 Conclusions; References; 7 Energetics of the Interaction of Human Acidic Fibroblast Growth Factor with Heparin and the Functional Analogue Myo-Inositol Hexasulfate; 7.1 Introduction
7.2 Thermodynamic parameter derived from ITC experiments
Record Nr. UNINA-9910143744003321
Chichester ; ; Hoboken, NJ, : Wiley, c2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle
Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle
Edizione [2nd ed.]
Pubbl/distr/stampa Chichester ; ; Hoboken, NJ, : Wiley, c2004
Descrizione fisica 1 online resource (277 p.)
Disciplina 572.43
572.436
Altri autori (Persone) LadburyJohn E. <1960->
DoyleMichael L. <1959->
Soggetto topico Calorimetry
Biology - Technique
ISBN 1-280-27608-8
9786610276080
0-470-01112-2
0-470-01111-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Biocalorimetry 2; Contents; Preface; List of Contributors; Part I General Introduction; 1 Applications of Biocalorimetry: Binding, Stability and Enzyme Kinetics; 1.1 Introduction; 1.2 Principles of isothermal titration calorimetry (ITC); 1.3 Applications of ITC in the life sciences; 1.4 Thermodynamic signatures of non-covalent interactions; 1.5 Thermodynamic discrimination (TD); 1.6 ITC as a tool for studying drug-DNA interactions; 1.7 ITC as a tool for studying protein-DNA interactions; 1.8 The application of calorimetry for examining hydration effcts
1.9 The use of ITC for studying the kinetics and thermodynamics of enzyme catalysis1.10 Principles of differential scanning calorimetry (DSC); 1.11 Applications of DSC in the life sciences; 1.12 Thermodynamic stability; 1.13 Shelf life versus thermodynamic stability; 1.14 Specific and non-specific binding; 1.15 Intrinsic and extrinsic macromolecular stability; 1.16 Oligomerization; 1.17 The use of DSC for examining nucleic acid helix coil transitions; 1.18 Summary; Acknowledgements; References; Part II Isothermal Titration Calorimetry; 2 Isothermal Titration Calorimetry: A Tutorial
2.1 Introduction2.2 Thermodynamic characterization; 2.3 Instrumentation; 2.4 Raw data; 2.5 Basic considerations for experimental set-up; 2.6 Data analysis; 2.7 Summary; Application notes; Acknowledgement; References; 3 The Application of Isothermal Titration Calorimetry to Drug Discovery; 3.1 Introduction; 3.2 Overview of the drug discovery process; 3.3 Experimental measurement of thermodynamic binding parameters; 3.4 ITC in drug discovery; 3.5 Summary; References; 4 Dissecting the Thermodynamics of DNA-Protein Interactions; 4.1 Introduction; 4.2 Model systems
4.3 Comparison with the hydrophobic effect4.4 Protonation and charged-charged hydrogen bonds; 4.5 Dissection of the binding entropy; 4.6 Entropy contributions to the Sso7d-DNA interaction; 4.7 Entropy contributions to the GCN4-DNA interaction; 4.8 Discussion; Acknowledgements; References; 5 Salt Effects in Ribonuclease-Ligand Interactions: Screening or Competitive Binding?; 5.1 Introduction; 5.2 Anion binding to a protein-protein complex; 5.3 Charge-charge interactions in ribonuclease binding; 5.4 Conclusions; Acknowledgement; References
6 Thermodynamics-Structure Correlations of Sulfonamide Inhibitor Binding to Carbonic Anhydrase6.1 Introduction; 6.2 Identification of protonation reactions occurring upon binding; 6.3 Observed thermodynamics of inhibitor binding to CA; 6.4 Energetics of inhibitor protonation; 6.5 Sulfonamide 'anion' binding thermodynamics; 6.6 Correlations between structures and the thermodynamics of sulfonamide binding to CA; 6.7 Conclusions; References; 7 Energetics of the Interaction of Human Acidic Fibroblast Growth Factor with Heparin and the Functional Analogue Myo-Inositol Hexasulfate; 7.1 Introduction
7.2 Thermodynamic parameter derived from ITC experiments
Record Nr. UNINA-9910830141503321
Chichester ; ; Hoboken, NJ, : Wiley, c2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
Autore Alberty Robert A
Pubbl/distr/stampa Hoboken, N.J. ; ; Chichester, : John Wiley, c2006
Descrizione fisica 1 online resource (482 p.)
Disciplina 572.436
Collana Methods of biochemical analysis
Soggetto topico Thermodynamics - Mathematics
Physical biochemistry
Bioenergetics
ISBN 1-280-41123-6
9786610411238
0-470-03646-X
0-470-03645-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Biochemical Thermodynamics: Applications of Mathernatica; Contents; Preface; Chapter 1 Thermodynamics of the Dissociation of Weak Acids; Chapter 2 Introduction to Apparent Equilibrium Constants; Chapter 3 Biochemical Reactions at Specified Temperature and Various pHs; Chapter 4 Biochemical Reactions at Various pHs and Various Temperatures; Chapter 5 Biochemical Reactions at Various pHs, pMgs, and Various Temperatures; Chapter 6 Development of a Database on Species; Chapter 7 Uses of Matrices in Biochemical Thermodynamics; Chapter 8 Oxidoreductase Reactions (Class 1) at 298.15 K
Chapter 9 Transferase Reactions (Class 2) at 298.15 KChapter 10 Hydrolase Reactions (Class 3) at 298.15 K; Chapter 11 Lyase Reactions (Class 4), Isomerase Reactions (Class 5), and Ligase Reactions (Class 6) at 298.15 K; Chapter 12 Survey of Reactions at 298.15 K; Chapter 13 Survey of Reactions at Various Temperatures; Chapter 14 Thermodynamics of th Binding of Ligands by Proteins; Chapter 15 Calorimetry of Biochemical Reactions; Appendix; 1. BasicBiochemData3.nb; 2. Tables of Transformed Thermodynamic Properties; 3. Glossary of Names of Reactants
4. Glossary of Symbols for Thermodynamic Properties5. List of Mathematica Programs; 6. Sources of Biochemical Thermodynamic Information on the Web; Index
Record Nr. UNINA-9910143408003321
Alberty Robert A  
Hoboken, N.J. ; ; Chichester, : John Wiley, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
Autore Alberty Robert A
Pubbl/distr/stampa Hoboken, N.J. ; ; Chichester, : John Wiley, c2006
Descrizione fisica 1 online resource (482 p.)
Disciplina 572.436
Collana Methods of biochemical analysis
Soggetto topico Thermodynamics - Mathematics
Physical biochemistry
Bioenergetics
Termodinàmica
Bioquímica física
Bioenergètica
Soggetto genere / forma Llibres electrònics
ISBN 1-280-41123-6
9786610411238
0-470-03646-X
0-470-03645-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Biochemical Thermodynamics: Applications of Mathernatica; Contents; Preface; Chapter 1 Thermodynamics of the Dissociation of Weak Acids; Chapter 2 Introduction to Apparent Equilibrium Constants; Chapter 3 Biochemical Reactions at Specified Temperature and Various pHs; Chapter 4 Biochemical Reactions at Various pHs and Various Temperatures; Chapter 5 Biochemical Reactions at Various pHs, pMgs, and Various Temperatures; Chapter 6 Development of a Database on Species; Chapter 7 Uses of Matrices in Biochemical Thermodynamics; Chapter 8 Oxidoreductase Reactions (Class 1) at 298.15 K
Chapter 9 Transferase Reactions (Class 2) at 298.15 KChapter 10 Hydrolase Reactions (Class 3) at 298.15 K; Chapter 11 Lyase Reactions (Class 4), Isomerase Reactions (Class 5), and Ligase Reactions (Class 6) at 298.15 K; Chapter 12 Survey of Reactions at 298.15 K; Chapter 13 Survey of Reactions at Various Temperatures; Chapter 14 Thermodynamics of th Binding of Ligands by Proteins; Chapter 15 Calorimetry of Biochemical Reactions; Appendix; 1. BasicBiochemData3.nb; 2. Tables of Transformed Thermodynamic Properties; 3. Glossary of Names of Reactants
4. Glossary of Symbols for Thermodynamic Properties5. List of Mathematica Programs; 6. Sources of Biochemical Thermodynamic Information on the Web; Index
Record Nr. UNINA-9910830896403321
Alberty Robert A  
Hoboken, N.J. ; ; Chichester, : John Wiley, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
Autore Alberty Robert A
Pubbl/distr/stampa Hoboken, N.J. ; ; Chichester, : John Wiley, c2006
Descrizione fisica 1 online resource (482 p.)
Disciplina 572.436
Collana Methods of biochemical analysis
Soggetto topico Thermodynamics - Mathematics
Physical biochemistry
Bioenergetics
Termodinàmica
Bioquímica física
Bioenergètica
Soggetto genere / forma Llibres electrònics
ISBN 1-280-41123-6
9786610411238
0-470-03646-X
0-470-03645-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Biochemical Thermodynamics: Applications of Mathernatica; Contents; Preface; Chapter 1 Thermodynamics of the Dissociation of Weak Acids; Chapter 2 Introduction to Apparent Equilibrium Constants; Chapter 3 Biochemical Reactions at Specified Temperature and Various pHs; Chapter 4 Biochemical Reactions at Various pHs and Various Temperatures; Chapter 5 Biochemical Reactions at Various pHs, pMgs, and Various Temperatures; Chapter 6 Development of a Database on Species; Chapter 7 Uses of Matrices in Biochemical Thermodynamics; Chapter 8 Oxidoreductase Reactions (Class 1) at 298.15 K
Chapter 9 Transferase Reactions (Class 2) at 298.15 KChapter 10 Hydrolase Reactions (Class 3) at 298.15 K; Chapter 11 Lyase Reactions (Class 4), Isomerase Reactions (Class 5), and Ligase Reactions (Class 6) at 298.15 K; Chapter 12 Survey of Reactions at 298.15 K; Chapter 13 Survey of Reactions at Various Temperatures; Chapter 14 Thermodynamics of th Binding of Ligands by Proteins; Chapter 15 Calorimetry of Biochemical Reactions; Appendix; 1. BasicBiochemData3.nb; 2. Tables of Transformed Thermodynamic Properties; 3. Glossary of Names of Reactants
4. Glossary of Symbols for Thermodynamic Properties5. List of Mathematica Programs; 6. Sources of Biochemical Thermodynamic Information on the Web; Index
Record Nr. UNINA-9911020062503321
Alberty Robert A  
Hoboken, N.J. ; ; Chichester, : John Wiley, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biochemical thermodynamics / / by Juan S. Jiménez
Biochemical thermodynamics / / by Juan S. Jiménez
Autore Jiménez Juan S.
Pubbl/distr/stampa Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020]
Descrizione fisica 1 online resource (xi, 325 pages)
Disciplina 572.436
Soggetto topico Biothermodynamics
Soggetto genere / forma Electronic books.
ISBN 1-5275-5685-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910493686803321
Jiménez Juan S.  
Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biochemical thermodynamics / / by Juan S. Jiménez
Biochemical thermodynamics / / by Juan S. Jiménez
Autore Jiménez Juan S.
Pubbl/distr/stampa Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020]
Descrizione fisica 1 online resource (xi, 325 pages)
Disciplina 572.436
Soggetto topico Biothermodynamics
ISBN 1-5275-5685-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910794399403321
Jiménez Juan S.  
Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biochemical thermodynamics / / by Juan S. Jiménez
Biochemical thermodynamics / / by Juan S. Jiménez
Autore Jiménez Juan S.
Pubbl/distr/stampa Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020]
Descrizione fisica 1 online resource (xi, 325 pages)
Disciplina 572.436
Soggetto topico Biothermodynamics
ISBN 1-5275-5685-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910823966703321
Jiménez Juan S.  
Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biothermodynamics, Part A / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers
Biothermodynamics, Part A / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers
Pubbl/distr/stampa Amsterdam [etc.], : Elsevier, 2009
Descrizione fisica XLIII, 466 p., [4] p. di tav. : ill. ; 24 cm
Disciplina 572.436
Collana Methods in enzymology
Soggetto topico Termodinamica
ISBN 978-0-12-374596-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNISA-990003273670203316
Amsterdam [etc.], : Elsevier, 2009
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Biothermodynamics, Part B / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers
Biothermodynamics, Part B / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers
Pubbl/distr/stampa Amsterdam [etc.], : Elsevier, 2009
Descrizione fisica XLVIII, 613 p., [6] p. di tav. : ill. ; 24 cm
Disciplina 572.436
Collana Methods in enzymology
Soggetto topico Termodinamica
ISBN 978-0-12-374776-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNISA-990003372870203316
Amsterdam [etc.], : Elsevier, 2009
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui