Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle
| Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley, c2004 |
| Descrizione fisica | 1 online resource (277 p.) |
| Disciplina |
572.43
572.436 |
| Altri autori (Persone) |
LadburyJohn E. <1960->
DoyleMichael L. <1959-> |
| Soggetto topico |
Calorimetry
Biology - Technique |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-27608-8
9786610276080 0-470-01112-2 0-470-01111-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biocalorimetry 2; Contents; Preface; List of Contributors; Part I General Introduction; 1 Applications of Biocalorimetry: Binding, Stability and Enzyme Kinetics; 1.1 Introduction; 1.2 Principles of isothermal titration calorimetry (ITC); 1.3 Applications of ITC in the life sciences; 1.4 Thermodynamic signatures of non-covalent interactions; 1.5 Thermodynamic discrimination (TD); 1.6 ITC as a tool for studying drug-DNA interactions; 1.7 ITC as a tool for studying protein-DNA interactions; 1.8 The application of calorimetry for examining hydration effcts
1.9 The use of ITC for studying the kinetics and thermodynamics of enzyme catalysis1.10 Principles of differential scanning calorimetry (DSC); 1.11 Applications of DSC in the life sciences; 1.12 Thermodynamic stability; 1.13 Shelf life versus thermodynamic stability; 1.14 Specific and non-specific binding; 1.15 Intrinsic and extrinsic macromolecular stability; 1.16 Oligomerization; 1.17 The use of DSC for examining nucleic acid helix coil transitions; 1.18 Summary; Acknowledgements; References; Part II Isothermal Titration Calorimetry; 2 Isothermal Titration Calorimetry: A Tutorial 2.1 Introduction2.2 Thermodynamic characterization; 2.3 Instrumentation; 2.4 Raw data; 2.5 Basic considerations for experimental set-up; 2.6 Data analysis; 2.7 Summary; Application notes; Acknowledgement; References; 3 The Application of Isothermal Titration Calorimetry to Drug Discovery; 3.1 Introduction; 3.2 Overview of the drug discovery process; 3.3 Experimental measurement of thermodynamic binding parameters; 3.4 ITC in drug discovery; 3.5 Summary; References; 4 Dissecting the Thermodynamics of DNA-Protein Interactions; 4.1 Introduction; 4.2 Model systems 4.3 Comparison with the hydrophobic effect4.4 Protonation and charged-charged hydrogen bonds; 4.5 Dissection of the binding entropy; 4.6 Entropy contributions to the Sso7d-DNA interaction; 4.7 Entropy contributions to the GCN4-DNA interaction; 4.8 Discussion; Acknowledgements; References; 5 Salt Effects in Ribonuclease-Ligand Interactions: Screening or Competitive Binding?; 5.1 Introduction; 5.2 Anion binding to a protein-protein complex; 5.3 Charge-charge interactions in ribonuclease binding; 5.4 Conclusions; Acknowledgement; References 6 Thermodynamics-Structure Correlations of Sulfonamide Inhibitor Binding to Carbonic Anhydrase6.1 Introduction; 6.2 Identification of protonation reactions occurring upon binding; 6.3 Observed thermodynamics of inhibitor binding to CA; 6.4 Energetics of inhibitor protonation; 6.5 Sulfonamide 'anion' binding thermodynamics; 6.6 Correlations between structures and the thermodynamics of sulfonamide binding to CA; 6.7 Conclusions; References; 7 Energetics of the Interaction of Human Acidic Fibroblast Growth Factor with Heparin and the Functional Analogue Myo-Inositol Hexasulfate; 7.1 Introduction 7.2 Thermodynamic parameter derived from ITC experiments |
| Record Nr. | UNINA-9910143744003321 |
| Chichester ; ; Hoboken, NJ, : Wiley, c2004 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle
| Biocalorimetry 2 [[electronic resource] ] : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley, c2004 |
| Descrizione fisica | 1 online resource (277 p.) |
| Disciplina |
572.43
572.436 |
| Altri autori (Persone) |
LadburyJohn E. <1960->
DoyleMichael L. <1959-> |
| Soggetto topico |
Calorimetry
Biology - Technique |
| ISBN |
1-280-27608-8
9786610276080 0-470-01112-2 0-470-01111-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biocalorimetry 2; Contents; Preface; List of Contributors; Part I General Introduction; 1 Applications of Biocalorimetry: Binding, Stability and Enzyme Kinetics; 1.1 Introduction; 1.2 Principles of isothermal titration calorimetry (ITC); 1.3 Applications of ITC in the life sciences; 1.4 Thermodynamic signatures of non-covalent interactions; 1.5 Thermodynamic discrimination (TD); 1.6 ITC as a tool for studying drug-DNA interactions; 1.7 ITC as a tool for studying protein-DNA interactions; 1.8 The application of calorimetry for examining hydration effcts
1.9 The use of ITC for studying the kinetics and thermodynamics of enzyme catalysis1.10 Principles of differential scanning calorimetry (DSC); 1.11 Applications of DSC in the life sciences; 1.12 Thermodynamic stability; 1.13 Shelf life versus thermodynamic stability; 1.14 Specific and non-specific binding; 1.15 Intrinsic and extrinsic macromolecular stability; 1.16 Oligomerization; 1.17 The use of DSC for examining nucleic acid helix coil transitions; 1.18 Summary; Acknowledgements; References; Part II Isothermal Titration Calorimetry; 2 Isothermal Titration Calorimetry: A Tutorial 2.1 Introduction2.2 Thermodynamic characterization; 2.3 Instrumentation; 2.4 Raw data; 2.5 Basic considerations for experimental set-up; 2.6 Data analysis; 2.7 Summary; Application notes; Acknowledgement; References; 3 The Application of Isothermal Titration Calorimetry to Drug Discovery; 3.1 Introduction; 3.2 Overview of the drug discovery process; 3.3 Experimental measurement of thermodynamic binding parameters; 3.4 ITC in drug discovery; 3.5 Summary; References; 4 Dissecting the Thermodynamics of DNA-Protein Interactions; 4.1 Introduction; 4.2 Model systems 4.3 Comparison with the hydrophobic effect4.4 Protonation and charged-charged hydrogen bonds; 4.5 Dissection of the binding entropy; 4.6 Entropy contributions to the Sso7d-DNA interaction; 4.7 Entropy contributions to the GCN4-DNA interaction; 4.8 Discussion; Acknowledgements; References; 5 Salt Effects in Ribonuclease-Ligand Interactions: Screening or Competitive Binding?; 5.1 Introduction; 5.2 Anion binding to a protein-protein complex; 5.3 Charge-charge interactions in ribonuclease binding; 5.4 Conclusions; Acknowledgement; References 6 Thermodynamics-Structure Correlations of Sulfonamide Inhibitor Binding to Carbonic Anhydrase6.1 Introduction; 6.2 Identification of protonation reactions occurring upon binding; 6.3 Observed thermodynamics of inhibitor binding to CA; 6.4 Energetics of inhibitor protonation; 6.5 Sulfonamide 'anion' binding thermodynamics; 6.6 Correlations between structures and the thermodynamics of sulfonamide binding to CA; 6.7 Conclusions; References; 7 Energetics of the Interaction of Human Acidic Fibroblast Growth Factor with Heparin and the Functional Analogue Myo-Inositol Hexasulfate; 7.1 Introduction 7.2 Thermodynamic parameter derived from ITC experiments |
| Record Nr. | UNINA-9910830141503321 |
| Chichester ; ; Hoboken, NJ, : Wiley, c2004 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
| Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty |
| Autore | Alberty Robert A |
| Pubbl/distr/stampa | Hoboken, N.J. ; ; Chichester, : John Wiley, c2006 |
| Descrizione fisica | 1 online resource (482 p.) |
| Disciplina | 572.436 |
| Collana | Methods of biochemical analysis |
| Soggetto topico |
Thermodynamics - Mathematics
Physical biochemistry Bioenergetics |
| ISBN |
1-280-41123-6
9786610411238 0-470-03646-X 0-470-03645-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biochemical Thermodynamics: Applications of Mathernatica; Contents; Preface; Chapter 1 Thermodynamics of the Dissociation of Weak Acids; Chapter 2 Introduction to Apparent Equilibrium Constants; Chapter 3 Biochemical Reactions at Specified Temperature and Various pHs; Chapter 4 Biochemical Reactions at Various pHs and Various Temperatures; Chapter 5 Biochemical Reactions at Various pHs, pMgs, and Various Temperatures; Chapter 6 Development of a Database on Species; Chapter 7 Uses of Matrices in Biochemical Thermodynamics; Chapter 8 Oxidoreductase Reactions (Class 1) at 298.15 K
Chapter 9 Transferase Reactions (Class 2) at 298.15 KChapter 10 Hydrolase Reactions (Class 3) at 298.15 K; Chapter 11 Lyase Reactions (Class 4), Isomerase Reactions (Class 5), and Ligase Reactions (Class 6) at 298.15 K; Chapter 12 Survey of Reactions at 298.15 K; Chapter 13 Survey of Reactions at Various Temperatures; Chapter 14 Thermodynamics of th Binding of Ligands by Proteins; Chapter 15 Calorimetry of Biochemical Reactions; Appendix; 1. BasicBiochemData3.nb; 2. Tables of Transformed Thermodynamic Properties; 3. Glossary of Names of Reactants 4. Glossary of Symbols for Thermodynamic Properties5. List of Mathematica Programs; 6. Sources of Biochemical Thermodynamic Information on the Web; Index |
| Record Nr. | UNINA-9910143408003321 |
Alberty Robert A
|
||
| Hoboken, N.J. ; ; Chichester, : John Wiley, c2006 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
| Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty |
| Autore | Alberty Robert A |
| Pubbl/distr/stampa | Hoboken, N.J. ; ; Chichester, : John Wiley, c2006 |
| Descrizione fisica | 1 online resource (482 p.) |
| Disciplina | 572.436 |
| Collana | Methods of biochemical analysis |
| Soggetto topico |
Thermodynamics - Mathematics
Physical biochemistry Bioenergetics Termodinàmica Bioquímica física Bioenergètica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
1-280-41123-6
9786610411238 0-470-03646-X 0-470-03645-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biochemical Thermodynamics: Applications of Mathernatica; Contents; Preface; Chapter 1 Thermodynamics of the Dissociation of Weak Acids; Chapter 2 Introduction to Apparent Equilibrium Constants; Chapter 3 Biochemical Reactions at Specified Temperature and Various pHs; Chapter 4 Biochemical Reactions at Various pHs and Various Temperatures; Chapter 5 Biochemical Reactions at Various pHs, pMgs, and Various Temperatures; Chapter 6 Development of a Database on Species; Chapter 7 Uses of Matrices in Biochemical Thermodynamics; Chapter 8 Oxidoreductase Reactions (Class 1) at 298.15 K
Chapter 9 Transferase Reactions (Class 2) at 298.15 KChapter 10 Hydrolase Reactions (Class 3) at 298.15 K; Chapter 11 Lyase Reactions (Class 4), Isomerase Reactions (Class 5), and Ligase Reactions (Class 6) at 298.15 K; Chapter 12 Survey of Reactions at 298.15 K; Chapter 13 Survey of Reactions at Various Temperatures; Chapter 14 Thermodynamics of th Binding of Ligands by Proteins; Chapter 15 Calorimetry of Biochemical Reactions; Appendix; 1. BasicBiochemData3.nb; 2. Tables of Transformed Thermodynamic Properties; 3. Glossary of Names of Reactants 4. Glossary of Symbols for Thermodynamic Properties5. List of Mathematica Programs; 6. Sources of Biochemical Thermodynamic Information on the Web; Index |
| Record Nr. | UNINA-9910830896403321 |
Alberty Robert A
|
||
| Hoboken, N.J. ; ; Chichester, : John Wiley, c2006 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty
| Biochemical thermodynamics [[electronic resource] ] : applications of Mathematica / / Robert A. Alberty |
| Autore | Alberty Robert A |
| Pubbl/distr/stampa | Hoboken, N.J. ; ; Chichester, : John Wiley, c2006 |
| Descrizione fisica | 1 online resource (482 p.) |
| Disciplina | 572.436 |
| Collana | Methods of biochemical analysis |
| Soggetto topico |
Thermodynamics - Mathematics
Physical biochemistry Bioenergetics Termodinàmica Bioquímica física Bioenergètica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
1-280-41123-6
9786610411238 0-470-03646-X 0-470-03645-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biochemical Thermodynamics: Applications of Mathernatica; Contents; Preface; Chapter 1 Thermodynamics of the Dissociation of Weak Acids; Chapter 2 Introduction to Apparent Equilibrium Constants; Chapter 3 Biochemical Reactions at Specified Temperature and Various pHs; Chapter 4 Biochemical Reactions at Various pHs and Various Temperatures; Chapter 5 Biochemical Reactions at Various pHs, pMgs, and Various Temperatures; Chapter 6 Development of a Database on Species; Chapter 7 Uses of Matrices in Biochemical Thermodynamics; Chapter 8 Oxidoreductase Reactions (Class 1) at 298.15 K
Chapter 9 Transferase Reactions (Class 2) at 298.15 KChapter 10 Hydrolase Reactions (Class 3) at 298.15 K; Chapter 11 Lyase Reactions (Class 4), Isomerase Reactions (Class 5), and Ligase Reactions (Class 6) at 298.15 K; Chapter 12 Survey of Reactions at 298.15 K; Chapter 13 Survey of Reactions at Various Temperatures; Chapter 14 Thermodynamics of th Binding of Ligands by Proteins; Chapter 15 Calorimetry of Biochemical Reactions; Appendix; 1. BasicBiochemData3.nb; 2. Tables of Transformed Thermodynamic Properties; 3. Glossary of Names of Reactants 4. Glossary of Symbols for Thermodynamic Properties5. List of Mathematica Programs; 6. Sources of Biochemical Thermodynamic Information on the Web; Index |
| Record Nr. | UNINA-9911020062503321 |
Alberty Robert A
|
||
| Hoboken, N.J. ; ; Chichester, : John Wiley, c2006 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biochemical thermodynamics / / by Juan S. Jiménez
| Biochemical thermodynamics / / by Juan S. Jiménez |
| Autore | Jiménez Juan S. |
| Pubbl/distr/stampa | Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020] |
| Descrizione fisica | 1 online resource (xi, 325 pages) |
| Disciplina | 572.436 |
| Soggetto topico | Biothermodynamics |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-5275-5685-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910493686803321 |
Jiménez Juan S.
|
||
| Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020] | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biochemical thermodynamics / / by Juan S. Jiménez
| Biochemical thermodynamics / / by Juan S. Jiménez |
| Autore | Jiménez Juan S. |
| Pubbl/distr/stampa | Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020] |
| Descrizione fisica | 1 online resource (xi, 325 pages) |
| Disciplina | 572.436 |
| Soggetto topico | Biothermodynamics |
| ISBN | 1-5275-5685-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910794399403321 |
Jiménez Juan S.
|
||
| Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020] | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biochemical thermodynamics / / by Juan S. Jiménez
| Biochemical thermodynamics / / by Juan S. Jiménez |
| Autore | Jiménez Juan S. |
| Pubbl/distr/stampa | Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020] |
| Descrizione fisica | 1 online resource (xi, 325 pages) |
| Disciplina | 572.436 |
| Soggetto topico | Biothermodynamics |
| ISBN | 1-5275-5685-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910823966703321 |
Jiménez Juan S.
|
||
| Newcastle upon Tyne, England : , : Cambridge Scholars Publishing, , [2020] | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biothermodynamics, Part A / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers
| Biothermodynamics, Part A / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers |
| Pubbl/distr/stampa | Amsterdam [etc.], : Elsevier, 2009 |
| Descrizione fisica | XLIII, 466 p., [4] p. di tav. : ill. ; 24 cm |
| Disciplina | 572.436 |
| Collana | Methods in enzymology |
| Soggetto topico | Termodinamica |
| ISBN | 978-0-12-374596-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990003273670203316 |
| Amsterdam [etc.], : Elsevier, 2009 | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Biothermodynamics, Part B / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers
| Biothermodynamics, Part B / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers |
| Pubbl/distr/stampa | Amsterdam [etc.], : Elsevier, 2009 |
| Descrizione fisica | XLVIII, 613 p., [6] p. di tav. : ill. ; 24 cm |
| Disciplina | 572.436 |
| Collana | Methods in enzymology |
| Soggetto topico | Termodinamica |
| ISBN | 978-0-12-374776-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990003372870203316 |
| Amsterdam [etc.], : Elsevier, 2009 | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||