Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Chemistry of protein and nucleic acid cross-linking and conjugation / / Shan S. Wong, David M. Jameson
| Chemistry of protein and nucleic acid cross-linking and conjugation / / Shan S. Wong, David M. Jameson |
| Autore | Wong Shan S. |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , 2012 |
| Descrizione fisica | 1 online resource (608 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) |
JamesonDavid M
WongShan S |
| Soggetto topico |
Proteins - Crosslinking
Nucleic acids - Structure |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-429-12723-5
1-283-34975-2 9786613349750 1-4200-0764-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Contents; Preface; Authors; Chapter 1: Overview of Protein Conjugation; Chapter 2: Review of Protein and Nucleic Acid Chemistry; Chapter 3: Reagents Targeted to Specific Functional Groups; Chapter 4: How to Design and Choose Cross-Linking Reagents; Homobifunctional Cross-Linking Reagents; Chapter 6: Heterobifunctional Cross-Linkers; Chapter 7: Multifunctional Cross-Linking Reagents; Chapter 8: Monofunctional and Zero -Length Cross -Linking Reagents; Chapter 9: General Approaches for Chemical Cross-Linking; Chapter 10: Analysis of Cross-Linked Products
Chapter 11: Applications of Chemical Cross-Linking to the Study of Biological MacromoleculesChapter 12: Applications of Chemical Conjugation in the Preparation of Immunoconjugates and Immunogens; Chapter 13: Application of Chemical Conjugation for the Preparation of Immunotoxins and Other Drug Conjugates for Targeting Therapeutics; Chapter 14: Application of Chemical Conjugation to Solid-State Chemistry; Appendix A Amino Group-Directed Homobifunctional Cross-Linkers; Appendix B Sulfhydryl Group-Directed Homobifunctional Cross-Linkers Appendix C Phenolate- and Imidazolyl-Group-Directed Reagents: Bisdiazonium PrecursorsAppendix D Group Selective Heterobifunctional Cross-Linkers; Appendix E Photoactivatable Heterobifunctional Cross-Linking Reagents; Back Cover |
| Record Nr. | UNINA-9910457792103321 |
Wong Shan S.
|
||
| Boca Raton : , : CRC Press, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chemistry of protein and nucleic acid cross-linking and conjugation / / Shan S. Wong, David M. Jameson
| Chemistry of protein and nucleic acid cross-linking and conjugation / / Shan S. Wong, David M. Jameson |
| Autore | Wong Shan S. |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , 2012 |
| Descrizione fisica | 1 online resource (608 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) |
JamesonDavid M
WongShan S |
| Soggetto topico |
Proteins - Crosslinking
Nucleic acids - Structure |
| ISBN |
0-429-12723-5
1-283-34975-2 9786613349750 1-4200-0764-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Contents; Preface; Authors; Chapter 1: Overview of Protein Conjugation; Chapter 2: Review of Protein and Nucleic Acid Chemistry; Chapter 3: Reagents Targeted to Specific Functional Groups; Chapter 4: How to Design and Choose Cross-Linking Reagents; Homobifunctional Cross-Linking Reagents; Chapter 6: Heterobifunctional Cross-Linkers; Chapter 7: Multifunctional Cross-Linking Reagents; Chapter 8: Monofunctional and Zero -Length Cross -Linking Reagents; Chapter 9: General Approaches for Chemical Cross-Linking; Chapter 10: Analysis of Cross-Linked Products
Chapter 11: Applications of Chemical Cross-Linking to the Study of Biological MacromoleculesChapter 12: Applications of Chemical Conjugation in the Preparation of Immunoconjugates and Immunogens; Chapter 13: Application of Chemical Conjugation for the Preparation of Immunotoxins and Other Drug Conjugates for Targeting Therapeutics; Chapter 14: Application of Chemical Conjugation to Solid-State Chemistry; Appendix A Amino Group-Directed Homobifunctional Cross-Linkers; Appendix B Sulfhydryl Group-Directed Homobifunctional Cross-Linkers Appendix C Phenolate- and Imidazolyl-Group-Directed Reagents: Bisdiazonium PrecursorsAppendix D Group Selective Heterobifunctional Cross-Linkers; Appendix E Photoactivatable Heterobifunctional Cross-Linking Reagents; Back Cover |
| Record Nr. | UNINA-9910781932503321 |
|
Wong Shan S.
|
||
| Boca Raton : , : CRC Press, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chemistry of protein and nucleic acid cross-linking and conjugation / / Shan S. Wong and David M. Jameson
| Chemistry of protein and nucleic acid cross-linking and conjugation / / Shan S. Wong and David M. Jameson |
| Autore | Wong Shan S |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Boca Raton, : Taylor & Francis, 2012 |
| Descrizione fisica | 1 online resource (608 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) |
JamesonDavid M
WongShan S |
| Soggetto topico |
Proteins - Crosslinking
Nucleic acids - Structure |
| ISBN |
1-04-020277-2
0-429-12723-5 1-283-34975-2 9786613349750 1-4200-0764-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Contents; Preface; Authors; Chapter 1: Overview of Protein Conjugation; Chapter 2: Review of Protein and Nucleic Acid Chemistry; Chapter 3: Reagents Targeted to Specific Functional Groups; Chapter 4: How to Design and Choose Cross-Linking Reagents; Homobifunctional Cross-Linking Reagents; Chapter 6: Heterobifunctional Cross-Linkers; Chapter 7: Multifunctional Cross-Linking Reagents; Chapter 8: Monofunctional and Zero -Length Cross -Linking Reagents; Chapter 9: General Approaches for Chemical Cross-Linking; Chapter 10: Analysis of Cross-Linked Products
Chapter 11: Applications of Chemical Cross-Linking to the Study of Biological MacromoleculesChapter 12: Applications of Chemical Conjugation in the Preparation of Immunoconjugates and Immunogens; Chapter 13: Application of Chemical Conjugation for the Preparation of Immunotoxins and Other Drug Conjugates for Targeting Therapeutics; Chapter 14: Application of Chemical Conjugation to Solid-State Chemistry; Appendix A Amino Group-Directed Homobifunctional Cross-Linkers; Appendix B Sulfhydryl Group-Directed Homobifunctional Cross-Linkers Appendix C Phenolate- and Imidazolyl-Group-Directed Reagents: Bisdiazonium PrecursorsAppendix D Group Selective Heterobifunctional Cross-Linkers; Appendix E Photoactivatable Heterobifunctional Cross-Linking Reagents; Back Cover |
| Record Nr. | UNINA-9910970712503321 |
|
Wong Shan S
|
||
| Boca Raton, : Taylor & Francis, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Computational approaches to protein dynamics : from quantum to coarse-grained methods / / edited by Monika Fuxreiter
| Computational approaches to protein dynamics : from quantum to coarse-grained methods / / edited by Monika Fuxreiter |
| Edizione | [1st edition] |
| Pubbl/distr/stampa | Boca Raton ; ; London : , : CRC Press, , [2015] |
| Descrizione fisica | 1 online resource (458 p.) |
| Disciplina | 572/.633 |
| Collana | Series in computational biophysics |
| Soggetto topico | Protein engineering |
| ISBN |
0-429-19468-4
1-4822-9786-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | section 1. Introduction -- section 2. Enzymatic catalysis : multiscale QM/MM calculations -- section 3. Protein motions : flexibility analysis -- section 4. Approaches to intrinsically disordered proteins -- section 5. Large-scale dynamics -- section 6. Ensemble methods. |
| Record Nr. | UNINA-9910787963403321 |
| Boca Raton ; ; London : , : CRC Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Computational approaches to protein dynamics : from quantum to coarse-grained methods / / edited by Monika Fuxreiter
| Computational approaches to protein dynamics : from quantum to coarse-grained methods / / edited by Monika Fuxreiter |
| Edizione | [1st edition] |
| Pubbl/distr/stampa | Boca Raton ; ; London : , : CRC Press, , [2015] |
| Descrizione fisica | 1 online resource (458 p.) |
| Disciplina | 572/.633 |
| Collana | Series in computational biophysics |
| Soggetto topico | Protein engineering |
| ISBN |
0-429-19468-4
1-4822-9786-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | section 1. Introduction -- section 2. Enzymatic catalysis : multiscale QM/MM calculations -- section 3. Protein motions : flexibility analysis -- section 4. Approaches to intrinsically disordered proteins -- section 5. Large-scale dynamics -- section 6. Ensemble methods. |
| Record Nr. | UNINA-9910800185803321 |
| Boca Raton ; ; London : , : CRC Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foldases catalyzing the formation and isomerization of disulfide bonds in proteins [[electronic resource] /] / Natalya K. Nagradova
| Foldases catalyzing the formation and isomerization of disulfide bonds in proteins [[electronic resource] /] / Natalya K. Nagradova |
| Autore | Nagradova N. K (Natalia Konstantinovna) |
| Pubbl/distr/stampa | New York, : Nova Biomedical Books, c2009 |
| Descrizione fisica | 1 online resource (85 p.) |
| Disciplina | 572/.633 |
| Soggetto topico |
Protein disulfide isomerase
Protein folding |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60741-689-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""FOLDASES CATALYZING THE FORMATION AND ISOMERIZATION OF DISULFIDE BONDS IN PROTEINS""; ""Contents""; ""Preface ""; ""Introduction ""; ""Eukaryotic Protein Disulfide Isomerase (PDI)""; ""1.1. The Role of Protein Disulfide Isomerase in the Endoplasmic Reticulum""; ""1.2. Modular Organization of the PDI Molecule and the Role of Different Domains""; ""1.3. Functional Properties of PDI Active Centers. The pKa Values of Essential Cysteine Residues ""; ""1.4. Disulfide Isomerization: The Essential Function of PDI ""; ""1.5. Dithiol Oxidation Catalyzed by PDI ""
""1.6. The Role of Glutathione in Oxidative Protein Folding in Endoplasmic Reticulum """"Disulfide Bond Formation and Isomerization in Prokaryotes ""; ""2.1. A Pathway for Disulfide Bond Formation in the Periplasm ""; ""2.2. Similarities in Prokaryotic and Eukaryotic Disulfide Bond-Forming Pathways ""; ""2.3. A Pathway for Disulfide Bond Isomerization in the Periplasm ""; ""Conclusion ""; ""References ""; ""Index "" |
| Record Nr. | UNINA-9910454834003321 |
|
Nagradova N. K (Natalia Konstantinovna)
|
||
| New York, : Nova Biomedical Books, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foldases catalyzing the formation and isomerization of disulfide bonds in proteins [[electronic resource] /] / Natalya K. Nagradova
| Foldases catalyzing the formation and isomerization of disulfide bonds in proteins [[electronic resource] /] / Natalya K. Nagradova |
| Autore | Nagradova N. K (Natalia Konstantinovna) |
| Pubbl/distr/stampa | New York, : Nova Biomedical Books, c2009 |
| Descrizione fisica | 1 online resource (85 p.) |
| Disciplina | 572/.633 |
| Soggetto topico |
Protein disulfide isomerase
Protein folding |
| ISBN | 1-60741-689-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""FOLDASES CATALYZING THE FORMATION AND ISOMERIZATION OF DISULFIDE BONDS IN PROTEINS""; ""Contents""; ""Preface ""; ""Introduction ""; ""Eukaryotic Protein Disulfide Isomerase (PDI)""; ""1.1. The Role of Protein Disulfide Isomerase in the Endoplasmic Reticulum""; ""1.2. Modular Organization of the PDI Molecule and the Role of Different Domains""; ""1.3. Functional Properties of PDI Active Centers. The pKa Values of Essential Cysteine Residues ""; ""1.4. Disulfide Isomerization: The Essential Function of PDI ""; ""1.5. Dithiol Oxidation Catalyzed by PDI ""
""1.6. The Role of Glutathione in Oxidative Protein Folding in Endoplasmic Reticulum """"Disulfide Bond Formation and Isomerization in Prokaryotes ""; ""2.1. A Pathway for Disulfide Bond Formation in the Periplasm ""; ""2.2. Similarities in Prokaryotic and Eukaryotic Disulfide Bond-Forming Pathways ""; ""2.3. A Pathway for Disulfide Bond Isomerization in the Periplasm ""; ""Conclusion ""; ""References ""; ""Index "" |
| Record Nr. | UNINA-9910778030303321 |
|
Nagradova N. K (Natalia Konstantinovna)
|
||
| New York, : Nova Biomedical Books, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Introduction to protein structure prediction [[electronic resource] ] : methods and algorithms / / edited by Huzefa Rangwala, George Karypis
| Introduction to protein structure prediction [[electronic resource] ] : methods and algorithms / / edited by Huzefa Rangwala, George Karypis |
| Pubbl/distr/stampa | Hoboken, NJ, : Wiley, 2010 |
| Descrizione fisica | 1 online resource (532 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) |
RangwalaHuzefa
KarypisG (George) |
| Collana | Wiley series in bioinformatics |
| Soggetto topico |
Proteins - Structure - Mathematical models
Proteins - Structure - Computer simulation |
| ISBN |
1-118-09946-X
1-282-78286-X 9786612782862 0-470-88220-4 0-470-88219-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
INTRODUCTION TO PROTEIN STRUCTURE PREDICTION: Methods and Algorithms; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1: INTRODUCTION TO PROTEIN STRUCTURE PREDICTION; CHAPTER 2: CASP : A DRIVING FORCE IN PROTEIN STRUCTURE MODELING; CHAPTER 3: THE PROTEIN STRUCTURE INITIATIVE; CHAPTER 4: PREDICTION OF ONE - DIMENSIONAL STRUCTURAL PROPERTIES OF PROTEINS BY INTEGRATED NEURAL NETWORKS; CHAPTER 5: LOCAL STRUCTURE ALPHABETS; CHAPTER 6: SHEDDING LIGHT ON TRANSMEMBRANE TOPOLOGY; CHAPTER 7: CONTACT MAP PREDICTION BY MACHINE LEARNING
CHAPTER 8: A SURVEY OF REMOTE HOMOLOGY DETECTION AND FOLD RECOGNITION METHODS CHAPTER 9: INTEGRATIVE PROTEIN FOLD RECOGNITION BY ALIGNMENTS AND MACHINE LEARNING; CHAPTER 10: TASSER - BASED PROTEIN STRUCTURE PREDICTION; CHAPTER 11: COMPOSITE APPROACHES TO PROTEIN TERTIARY STRUCTURE PREDICTION: A CASE - STUDY BY I - TASSER; CHAPTER 12: HYBRID METHODS FOR PROTEIN STRUCTURE PREDICTION; CHAPTER 13: MODELING LOOPS IN PROTEIN STRUCTURES; CHAPTER 14: MODEL QUALITY ASSESSMENT USING A STATISTICAL PROGRAM THAT ADOPTS A SIDE CHAIN ENVIRONMENT VIEWPOINT; CHAPTER 15: MODEL QUALITY PREDICTION CHAPTER 16: LIGAND - BINDING RESIDUE PREDICTION CHAPTER 17: MODELING AND VALIDATION OF TRANSMEMBRANE PROTEIN STRUCTURES; CHAPTER 18: STRUCTURE - BASED MACHINE LEARNING MODELS FOR COMPUTATIONAL MUTAGENESIS; CHAPTER 19: CONFORMATIONAL SEARCH FOR THE PROTEIN NATIVE STATE; CHAPTER 20: MODELING MUTATIONS IN PROTEINS USING MEDUSA AND DISCRETE MOLECULE DYNAMICS; INDEX; colour plates |
| Record Nr. | UNINA-9910140761903321 |
| Hoboken, NJ, : Wiley, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Introduction to protein structure prediction : methods and algorithms / / edited by Huzefa Rangwala, George Karypis
| Introduction to protein structure prediction : methods and algorithms / / edited by Huzefa Rangwala, George Karypis |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, NJ, : Wiley, 2010 |
| Descrizione fisica | 1 online resource (532 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) |
RangwalaHuzefa
KarypisG (George) |
| Collana | Wiley series in bioinformatics |
| Soggetto topico |
Proteins - Structure - Mathematical models
Proteins - Structure - Computer simulation |
| ISBN |
9786612782862
9781118099469 111809946X 9781282782860 128278286X 9780470882207 0470882204 9780470882191 0470882190 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
INTRODUCTION TO PROTEIN STRUCTURE PREDICTION: Methods and Algorithms; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1: INTRODUCTION TO PROTEIN STRUCTURE PREDICTION; CHAPTER 2: CASP : A DRIVING FORCE IN PROTEIN STRUCTURE MODELING; CHAPTER 3: THE PROTEIN STRUCTURE INITIATIVE; CHAPTER 4: PREDICTION OF ONE - DIMENSIONAL STRUCTURAL PROPERTIES OF PROTEINS BY INTEGRATED NEURAL NETWORKS; CHAPTER 5: LOCAL STRUCTURE ALPHABETS; CHAPTER 6: SHEDDING LIGHT ON TRANSMEMBRANE TOPOLOGY; CHAPTER 7: CONTACT MAP PREDICTION BY MACHINE LEARNING
CHAPTER 8: A SURVEY OF REMOTE HOMOLOGY DETECTION AND FOLD RECOGNITION METHODS CHAPTER 9: INTEGRATIVE PROTEIN FOLD RECOGNITION BY ALIGNMENTS AND MACHINE LEARNING; CHAPTER 10: TASSER - BASED PROTEIN STRUCTURE PREDICTION; CHAPTER 11: COMPOSITE APPROACHES TO PROTEIN TERTIARY STRUCTURE PREDICTION: A CASE - STUDY BY I - TASSER; CHAPTER 12: HYBRID METHODS FOR PROTEIN STRUCTURE PREDICTION; CHAPTER 13: MODELING LOOPS IN PROTEIN STRUCTURES; CHAPTER 14: MODEL QUALITY ASSESSMENT USING A STATISTICAL PROGRAM THAT ADOPTS A SIDE CHAIN ENVIRONMENT VIEWPOINT; CHAPTER 15: MODEL QUALITY PREDICTION CHAPTER 16: LIGAND - BINDING RESIDUE PREDICTION CHAPTER 17: MODELING AND VALIDATION OF TRANSMEMBRANE PROTEIN STRUCTURES; CHAPTER 18: STRUCTURE - BASED MACHINE LEARNING MODELS FOR COMPUTATIONAL MUTAGENESIS; CHAPTER 19: CONFORMATIONAL SEARCH FOR THE PROTEIN NATIVE STATE; CHAPTER 20: MODELING MUTATIONS IN PROTEINS USING MEDUSA AND DISCRETE MOLECULE DYNAMICS; INDEX; colour plates |
| Record Nr. | UNINA-9910806241903321 |
| Hoboken, NJ, : Wiley, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor
| Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2008 |
| Descrizione fisica | 1 online resource (261 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) | BoggsJoan M |
| Collana | Intrinsically disordered proteins |
| Soggetto topico |
Myelin basic protein
Myelin sheath |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60876-247-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""MYELIN BASIC PROTEIN""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""REFERENCES""; ""THE PROPERTIES AND FUNCTIONS OF THE GOLLI MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""The MBP gene encodes the “classic� and golli family of proteins""; ""Features of the primary and higher ordered structure of the golli-MBPs""; ""Approaches to defining the biological roles of golli proteins in cells""; ""Unique phenotypes of the golli KO and golli overexpressing mice""; ""Emerging relevance of golli expression in pathology and disease""; ""CONCLUSION""; ""ACKNOWLEDGEMENTS""
""REFERENCES""""POSTTRANSLATIONAL MODIFICATIONS OF MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""ACETYLATION""; ""METHYLATION""; ""PHOSPHORYLATION""; ""Deamidation of glutamine at residues 103 and 147""; ""Deimination of arginine residues (citrullination)""; ""CONCLUSION""; ""REFERENCES""; ""DEIMINATION OF MYELIN BASIC PROTEIN BY PAD ENZYMES, AND THEIR ROLE IN MULTIPLE SCLEROSIS""; ""ABSTRACT""; ""INTRODUCTION""; ""MBP CHARGE ISOMERS""; ""CONSEQUENCES OF INCREASED CITRULLINATION OF MBP""; ""A. Proteolysis""; ""B. MBP autocatalysis and neoepitopes"" ""THE ROLE OF MYELIN BASIC PROTEIN IN MYELIN COMPACTION""""BILAYER STRUCTURE IN NORMAL APPEARING WHITE MATTER (NAWM) IN MS BRAIN IS NOT “NORMAL�""; ""MBP MICROHETEROGENEITY IN MS WHITE MATTER""; ""PEPTIDYL ARGININE DEIMINASES (PADS)""; ""THE PAD2 CPG ISLAND""; ""FUTURE DIRECTIONS AND CONCLUDING REMARKS""; ""ACKNOWLEDGEMENTS""; ""REFERENCES""; ""MYELIN BASIC PROTEIN-MEDIATED IMMUNOPATHOGENESIS IN MULTIPLE SCLEROSIS AND EAE""; ""ABSTRACT""; ""INTRODUCTION""; ""EXPRESSION OF MBP IN THE CNS AND THE IMMUNE SYSTEM""; ""MULTIPLE SCLEROSIS AND EAE"" ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN MS""""FREQUENCY AND PHENOTYPES OF CD4+ T CELLS IN MS PATIENTS""; ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN EAE""; ""EAE AND MS: TH1 VS. TH17?""; ""MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""HUMANIZED MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""MBP-SPECIFIC CD8+ T CELLS INVOLVED IN MS""; ""PATHOGENICITY OF MBP-SPECIFIC CD8+ T CELLS IS DEMONSTRATED IN NEW EAE MODELS""; ""B CELLS INVOLVED IN MS AND EAE""; ""IMMUNE TOLERANCE TO SELF-ANTIGENS""; ""CD4+ T CELL IMMUNE TOLERANCE TO MBP""; ""CD8+ T CELL IMMUNE TOLERANCE TO MBP""; ""CONCLUSION"" ""REFERENCES""""A STRUCTURAL PERSPECTIVE OF PEPTIDES FROM MYELIN BASIC PROTEIN""; ""ABSTRACT""; ""ABBREVIATIONS""; ""INTRODUCTION""; ""CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101, DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN MBP85-99""; ""Peptide interactions with HLA-DR2A""; ""Peptide interactions with Ob.1A.12 TCR""; ""STRUCTURE OF HUMAN MHC CLASS II COMPLEXED WITH A LONGER EPITOPE PEPTIDE (MBP86-105) FROM HUMAN MYELIN BASIC PROTEIN""; ""Interactions with HLA-DR2a / 2b""; ""Interactions with TCR"" ""Structure of a human TCR complexed with a peptide from human MBP89-101 and a MHC class II molecule"" |
| Record Nr. | UNINA-9910455361503321 |
| New York, : Nova Science Publishers, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
