Brain glucosensing [[electronic resource] ] : physiological implications / / Sergio Polakof |
Autore | Polakof Sergio |
Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publishers, c2010 |
Descrizione fisica | 1 online resource (79 p.) |
Disciplina | 572/.565 |
Collana | Neurology - laboratory and clinical research developments |
Soggetto topico |
Glucose - Metabolism
Brain Neurochemistry Homeostasis Blood glucose |
Soggetto genere / forma | Electronic books. |
ISBN | 1-61761-701-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""BRAIN GLUCOSENSING: PHYSIOLOGICAL IMPLICATIONS ""; ""BRAIN GLUCOSENSING: PHYSIOLOGICAL IMPLICATIONS""; ""Contents""; ""Preface""; ""Introduction""; ""Glucose Metabolism in the Brain""; ""Sites of Glucosensing in the Brain""; ""The Glucosensor Mechanism in the Brain""; ""4.1. Glucose-Excited Neurons""; ""4.1.1. Glucose Transport""; ""4.1.2. Glucose Phosphorylation""; ""4.1.3. Distal Sensing of Metabolic Signals""; ""4.2. Glucose-Inhibited Neurons""; ""Lactate as Metabolic Coupling between Astrocytes and Glucosensing Neurons""; ""Network of Hypothalamic Glucosensing Neurons""
""6.1. Neurons of the Arcuatus Nucleus""""6.2. Neurons of the Ventromedial Nucleus""; ""6.3. Neurons of the Lateral Nucleus""; ""The Mechanisms Underlying Glucosensing During Hypoglycemia""; ""7.1. Systemic Mechanism Against Hypoglycemia""; ""7.2. Metabolic Central Counterregulation""; ""7.3. Sites of Detection of Hypoglycemia""; ""7.4. Counterregulation to Hypoglycemia in T1DM: Why Glucosensor Mechanisms Fail?""; ""7.5. Glucosensing Markers Involved in the Counterregulatory Response to Hypoglycemia""; ""Brain Glucosensing and the Regulation of Food Intake and Energy Expenditure"" ""8.1. Glucosensing Markers Involved in The Control of Food Intake and Energy Expenditure""""Glucosensing Neurons as Metabolic Sensors""; ""Conclusion""; ""References""; ""Index"" |
Record Nr. | UNINA-9910461512003321 |
Polakof Sergio | ||
Hauppauge, NY, : Nova Science Publishers, c2010 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Brain glucosensing [[electronic resource] ] : physiological implications / / Sergio Polakof |
Autore | Polakof Sergio |
Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publishers, c2010 |
Descrizione fisica | 1 online resource (79 p.) |
Disciplina | 572/.565 |
Collana | Neurology - laboratory and clinical research developments |
Soggetto topico |
Glucose - Metabolism
Brain Neurochemistry Homeostasis Blood glucose |
ISBN | 1-61761-701-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""BRAIN GLUCOSENSING: PHYSIOLOGICAL IMPLICATIONS ""; ""BRAIN GLUCOSENSING: PHYSIOLOGICAL IMPLICATIONS""; ""Contents""; ""Preface""; ""Introduction""; ""Glucose Metabolism in the Brain""; ""Sites of Glucosensing in the Brain""; ""The Glucosensor Mechanism in the Brain""; ""4.1. Glucose-Excited Neurons""; ""4.1.1. Glucose Transport""; ""4.1.2. Glucose Phosphorylation""; ""4.1.3. Distal Sensing of Metabolic Signals""; ""4.2. Glucose-Inhibited Neurons""; ""Lactate as Metabolic Coupling between Astrocytes and Glucosensing Neurons""; ""Network of Hypothalamic Glucosensing Neurons""
""6.1. Neurons of the Arcuatus Nucleus""""6.2. Neurons of the Ventromedial Nucleus""; ""6.3. Neurons of the Lateral Nucleus""; ""The Mechanisms Underlying Glucosensing During Hypoglycemia""; ""7.1. Systemic Mechanism Against Hypoglycemia""; ""7.2. Metabolic Central Counterregulation""; ""7.3. Sites of Detection of Hypoglycemia""; ""7.4. Counterregulation to Hypoglycemia in T1DM: Why Glucosensor Mechanisms Fail?""; ""7.5. Glucosensing Markers Involved in the Counterregulatory Response to Hypoglycemia""; ""Brain Glucosensing and the Regulation of Food Intake and Energy Expenditure"" ""8.1. Glucosensing Markers Involved in The Control of Food Intake and Energy Expenditure""""Glucosensing Neurons as Metabolic Sensors""; ""Conclusion""; ""References""; ""Index"" |
Record Nr. | UNINA-9910790070103321 |
Polakof Sergio | ||
Hauppauge, NY, : Nova Science Publishers, c2010 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Brain glucosensing : physiological implications / / Sergio Polakof |
Autore | Polakof Sergio |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publishers, c2010 |
Descrizione fisica | 1 online resource (79 p.) |
Disciplina | 572/.565 |
Collana | Neurology - laboratory and clinical research developments |
Soggetto topico |
Glucose - Metabolism
Brain Neurochemistry Homeostasis Blood sugar |
ISBN | 1-61761-701-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""BRAIN GLUCOSENSING: PHYSIOLOGICAL IMPLICATIONS ""; ""BRAIN GLUCOSENSING: PHYSIOLOGICAL IMPLICATIONS""; ""Contents""; ""Preface""; ""Introduction""; ""Glucose Metabolism in the Brain""; ""Sites of Glucosensing in the Brain""; ""The Glucosensor Mechanism in the Brain""; ""4.1. Glucose-Excited Neurons""; ""4.1.1. Glucose Transport""; ""4.1.2. Glucose Phosphorylation""; ""4.1.3. Distal Sensing of Metabolic Signals""; ""4.2. Glucose-Inhibited Neurons""; ""Lactate as Metabolic Coupling between Astrocytes and Glucosensing Neurons""; ""Network of Hypothalamic Glucosensing Neurons""
""6.1. Neurons of the Arcuatus Nucleus""""6.2. Neurons of the Ventromedial Nucleus""; ""6.3. Neurons of the Lateral Nucleus""; ""The Mechanisms Underlying Glucosensing During Hypoglycemia""; ""7.1. Systemic Mechanism Against Hypoglycemia""; ""7.2. Metabolic Central Counterregulation""; ""7.3. Sites of Detection of Hypoglycemia""; ""7.4. Counterregulation to Hypoglycemia in T1DM: Why Glucosensor Mechanisms Fail?""; ""7.5. Glucosensing Markers Involved in the Counterregulatory Response to Hypoglycemia""; ""Brain Glucosensing and the Regulation of Food Intake and Energy Expenditure"" ""8.1. Glucosensing Markers Involved in The Control of Food Intake and Energy Expenditure""""Glucosensing Neurons as Metabolic Sensors""; ""Conclusion""; ""References""; ""Index"" |
Record Nr. | UNINA-9910816326003321 |
Polakof Sergio | ||
Hauppauge, NY, : Nova Science Publishers, c2010 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Food oligosaccharides : production, analysis, and bioactivity / / edited by Dr. F. Javier Moreno, Dr. María Luz Sanz |
Pubbl/distr/stampa | Chichester, England : , : IFT Press : , : Wiley-Blackwell, , 2014 |
Descrizione fisica | 1 online resource (564 pages) : illustrations |
Disciplina | 572/.565 |
Collana | IFT Press Series |
Soggetto topico |
Oligosaccharides
Oligosaccharides - Biotechnology Food - Carbohydrate content |
ISBN |
1-118-81736-2
1-118-81742-7 1-118-81734-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910208818503321 |
Chichester, England : , : IFT Press : , : Wiley-Blackwell, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Food oligosaccharides : production, analysis, and bioactivity / / edited by Dr. F. Javier Moreno, Dr. María Luz Sanz |
Pubbl/distr/stampa | Chichester, England : , : IFT Press : , : Wiley-Blackwell, , 2014 |
Descrizione fisica | 1 online resource (564 pages) : illustrations |
Disciplina | 572/.565 |
Collana | IFT Press Series |
Soggetto topico |
Oligosaccharides
Oligosaccharides - Biotechnology Food - Carbohydrate content |
ISBN |
1-118-81736-2
1-118-81742-7 1-118-81734-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910823303403321 |
Chichester, England : , : IFT Press : , : Wiley-Blackwell, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Oligosaccharides [[electronic resource] ] : sources, properties, and applications / / Nicole S. Gordon, editor |
Pubbl/distr/stampa | New York, : Nova Science Publishers, c2011 |
Descrizione fisica | 1 online resource (318 p.) |
Disciplina | 572/.565 |
Altri autori (Persone) | GordonNicole S |
Collana | Biochemistry research trends |
Soggetto topico |
Oligosaccharides
Carbohydrates |
Soggetto genere / forma | Electronic books. |
ISBN | 1-61122-424-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910461602503321 |
New York, : Nova Science Publishers, c2011 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Oligosaccharides [[electronic resource] ] : sources, properties, and applications / / Nicole S. Gordon, editor |
Pubbl/distr/stampa | New York, : Nova Science Publishers, c2011 |
Descrizione fisica | 1 online resource (318 p.) |
Disciplina | 572/.565 |
Altri autori (Persone) | GordonNicole S |
Collana | Biochemistry research trends |
Soggetto topico |
Oligosaccharides
Carbohydrates |
ISBN | 1-61122-424-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Milk oligosaccharides / Tadasu Urashima ... [et al.] -- Prebiotic oligosaccharides : origins and production, health benefits, and commercial applications / Santad Wichienchot, Pavinee Chinachoti -- Glycoside hydrolases from hyperthermophiles : structure, function, and exploitation in oligosaccharide synthesis -- Beatrice Cobucci-Ponzano, Mosè Rossi, Marco Moracci -- Enzymatic synthesis of linear, cyclic, and, complex type oligosaccharides / Piamsook Pongsawasdi, Kazuo Ito -- Precursor N-linked oligosaccharides as codes for glycoprotein folding status / Gerardo Z. Lederkremer -- Oligosaccharides from sucrose via glycansucrases / Gregory L. Côté -- Electrospray mass spectrometry of oligosaccharides of plant origin / Maria do Rosário M. Domingues, Fernando M. Nunes, Manuel A. Coimbra -- Biologically active oligosaccharide functions in plant cell : updates and prospects / Olga A. Zabotina and Aleksey I. Zabotin -- The Mannan oligosaccharides in aquaculture / Huynh Minh Sang, Ravi Fotedar -- Facile synthesis of unnatural oligosaccharides by phosphorylase-catalyzed enzymatic glycosylations using new glycosyl donors / Jun-ichi Kadokawa -- Oligosaccharides : sources, properties and applications / Kaoshan Chen, Yungui Bai. |
Record Nr. | UNINA-9910789402903321 |
New York, : Nova Science Publishers, c2011 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Oligosaccharides : sources, properties, and applications / / Nicole S. Gordon, editor |
Edizione | [1st ed.] |
Pubbl/distr/stampa | New York, : Nova Science Publishers, c2011 |
Descrizione fisica | 1 online resource (318 p.) |
Disciplina | 572/.565 |
Altri autori (Persone) | GordonNicole S |
Collana | Biochemistry research trends |
Soggetto topico |
Oligosaccharides
Carbohydrates |
ISBN | 1-61122-424-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Milk oligosaccharides / Tadasu Urashima ... [et al.] -- Prebiotic oligosaccharides : origins and production, health benefits, and commercial applications / Santad Wichienchot, Pavinee Chinachoti -- Glycoside hydrolases from hyperthermophiles : structure, function, and exploitation in oligosaccharide synthesis -- Beatrice Cobucci-Ponzano, Mosè Rossi, Marco Moracci -- Enzymatic synthesis of linear, cyclic, and, complex type oligosaccharides / Piamsook Pongsawasdi, Kazuo Ito -- Precursor N-linked oligosaccharides as codes for glycoprotein folding status / Gerardo Z. Lederkremer -- Oligosaccharides from sucrose via glycansucrases / Gregory L. Côté -- Electrospray mass spectrometry of oligosaccharides of plant origin / Maria do Rosário M. Domingues, Fernando M. Nunes, Manuel A. Coimbra -- Biologically active oligosaccharide functions in plant cell : updates and prospects / Olga A. Zabotina and Aleksey I. Zabotin -- The Mannan oligosaccharides in aquaculture / Huynh Minh Sang, Ravi Fotedar -- Facile synthesis of unnatural oligosaccharides by phosphorylase-catalyzed enzymatic glycosylations using new glycosyl donors / Jun-ichi Kadokawa -- Oligosaccharides : sources, properties and applications / Kaoshan Chen, Yungui Bai. |
Record Nr. | UNINA-9910819614003321 |
New York, : Nova Science Publishers, c2011 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Solid support oligosaccharide synthesis and combinatorial carbohydrate libraries [[electronic resource] /] / edited by Peter H. Seeberger |
Pubbl/distr/stampa | New York, : Wiley-Interscience, c2001 |
Descrizione fisica | 1 online resource (321 p.) |
Disciplina |
547.7815
572/.565 |
Altri autori (Persone) | SeebergerPeter H. <1966-> |
Soggetto topico |
Oligosaccharides - Synthesis
Glycoconjugates Combinatorial chemistry Solid-phase synthesis |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-54174-1
9786610541744 0-471-46072-9 0-471-22044-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents; Preface; Contributors; 1 Solid-Phase Carbohydrate Synthesis: The Early Work; 1.1 Introduction; 1.2 Solid-Phase Strategies; 1.3 Oligosaccharide Synthesis on Soluble Polymers; 1.4 The Period of Stagnancy (1976-1991); 2 The Glycal Assembly Method on Solid Supports: Synthesis of Oligosaccharides and Glycoconjugates; 2.1 Introduction; 2.2 Why Glycal Assembly? Strategic Considerations; 2.3 Linker Design; 2.4 Solid Support Glycal Assembly via 1,2-Anhydrosugar Donors; 2.5 Solid-Phase Synthesis of the Blood Group H Determinant; 2.6 Solid Support Glycal Assembly via Thioethyl Glycosyl Donors
2.7 Solid Support Assembly via Thioethyl 2-Amidoglycosyl Donors2.8 Solid-Phase Synthesis of the Lewis[sub(b)] Blood Group Determinant; 2.9 Solid-Phase Synthesis of the Hexasaccharide Globo-H Antigen: Progress and Limitations; 2.10 Solid-Phase Synthesis of N-Linked Glycopeptides; 2.11 Conclusions; 3 The Sulfoxide Glycosylation Method and its Application to Solid-Phase Oligosaccharide Synthesis and the Generation of Combinatorial Libraries; 3.1 Introduction; 3.2 Synthesis of Sulfoxide Donors; 3.3 Mechanism of the Sulfoxide Glycosylation; 3.4 Stereoselectivity 3.5 Solid-Phase Oligosaccharide Synthesis3.6 Libraries of Oligosaccharides; 3.7 Outlook; 4 The Use of O-Glycosyl Trichloroacetimidates for the Polymer-Supported Synthesis of Oligosaccharides; 4.1 Introduction; 4.2 Polystyrene-Based Supports; 4.3 Controlled-Pore Glass as a Solid Support; 4.4 Soluble Polymers as Supports; 4.5 Oligosaccharide Syntheses on Peptides Attached to a Solid Support; 4.6 Conclusions and Outlook; 5 Synthesis of Oligosaccharides on Solid Support Using Thioglycosides and Pentenyl Glycosides; 5.1 Introduction; 5.2 Thioglycosides as Glycosyl Donors 5.3 Pentenyl Glycosides as Glycosyl Donors6 Solid-Phase Oligosaccharide Synthesis Using Glycosyl Phosphates; 6.1 Introduction; 6.2 Glycosyl Phosphate Donors; 6.3 Other Phosphorous(V) Glycosyl Donors; 6.4 Conclusion; 7 Stereoselective β-Mannosylation on Polymer Support; 7.1 p-Methoxybenzyl-Assisted Intramolecular Aglycon Delivery: Highly Efficient β-mannosylation; 7.2 Intramolecular Aglycon Delivery on Polymer Support: Gatekeeper-Controlled Glycosylation; 7.3 Conclusions; 8 Tools for ""On-Bead"" Monitoring and Analysis in Solid-Phase Oligosaccharide Synthesis; 8.1 Introduction 8.2 IR Spectroscopic Methods8.3 NMR Spectroscopic Methods; 9 Polyethyleneglycol ω-Monomethylether (MPEG)-Supported Solution-Phase Synthesis of Oligosaccharides; 9.1 Introduction; 9.2 Polyethyleneglycol ω-Monomethylether (MPEG); 9.3 Linkers; 9.4 MPEG-Supported Syntheses Using Enzymes; 9.5 Use of MPEG in Mechanistic Studies; 9.6 MPEG and Combinatorial Libraries; 9.7 Other Applications; 9.8 Capping; 9.9 Outlook; 10 Two-Direction Glycosylations for the Preparation of Libraries of Oligosaccharides; 10.1 Two-Directional Glycosylations in Solution 10.2 Two-Directional Glycosylations on Solid Support |
Record Nr. | UNINA-9910143186803321 |
New York, : Wiley-Interscience, c2001 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Solid support oligosaccharide synthesis and combinatorial carbohydrate libraries [[electronic resource] /] / edited by Peter H. Seeberger |
Pubbl/distr/stampa | New York, : Wiley-Interscience, c2001 |
Descrizione fisica | 1 online resource (321 p.) |
Disciplina |
547.7815
572/.565 |
Altri autori (Persone) | SeebergerPeter H. <1966-> |
Soggetto topico |
Oligosaccharides - Synthesis
Glycoconjugates Combinatorial chemistry Solid-phase synthesis |
ISBN |
1-280-54174-1
9786610541744 0-471-46072-9 0-471-22044-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents; Preface; Contributors; 1 Solid-Phase Carbohydrate Synthesis: The Early Work; 1.1 Introduction; 1.2 Solid-Phase Strategies; 1.3 Oligosaccharide Synthesis on Soluble Polymers; 1.4 The Period of Stagnancy (1976-1991); 2 The Glycal Assembly Method on Solid Supports: Synthesis of Oligosaccharides and Glycoconjugates; 2.1 Introduction; 2.2 Why Glycal Assembly? Strategic Considerations; 2.3 Linker Design; 2.4 Solid Support Glycal Assembly via 1,2-Anhydrosugar Donors; 2.5 Solid-Phase Synthesis of the Blood Group H Determinant; 2.6 Solid Support Glycal Assembly via Thioethyl Glycosyl Donors
2.7 Solid Support Assembly via Thioethyl 2-Amidoglycosyl Donors2.8 Solid-Phase Synthesis of the Lewis[sub(b)] Blood Group Determinant; 2.9 Solid-Phase Synthesis of the Hexasaccharide Globo-H Antigen: Progress and Limitations; 2.10 Solid-Phase Synthesis of N-Linked Glycopeptides; 2.11 Conclusions; 3 The Sulfoxide Glycosylation Method and its Application to Solid-Phase Oligosaccharide Synthesis and the Generation of Combinatorial Libraries; 3.1 Introduction; 3.2 Synthesis of Sulfoxide Donors; 3.3 Mechanism of the Sulfoxide Glycosylation; 3.4 Stereoselectivity 3.5 Solid-Phase Oligosaccharide Synthesis3.6 Libraries of Oligosaccharides; 3.7 Outlook; 4 The Use of O-Glycosyl Trichloroacetimidates for the Polymer-Supported Synthesis of Oligosaccharides; 4.1 Introduction; 4.2 Polystyrene-Based Supports; 4.3 Controlled-Pore Glass as a Solid Support; 4.4 Soluble Polymers as Supports; 4.5 Oligosaccharide Syntheses on Peptides Attached to a Solid Support; 4.6 Conclusions and Outlook; 5 Synthesis of Oligosaccharides on Solid Support Using Thioglycosides and Pentenyl Glycosides; 5.1 Introduction; 5.2 Thioglycosides as Glycosyl Donors 5.3 Pentenyl Glycosides as Glycosyl Donors6 Solid-Phase Oligosaccharide Synthesis Using Glycosyl Phosphates; 6.1 Introduction; 6.2 Glycosyl Phosphate Donors; 6.3 Other Phosphorous(V) Glycosyl Donors; 6.4 Conclusion; 7 Stereoselective β-Mannosylation on Polymer Support; 7.1 p-Methoxybenzyl-Assisted Intramolecular Aglycon Delivery: Highly Efficient β-mannosylation; 7.2 Intramolecular Aglycon Delivery on Polymer Support: Gatekeeper-Controlled Glycosylation; 7.3 Conclusions; 8 Tools for ""On-Bead"" Monitoring and Analysis in Solid-Phase Oligosaccharide Synthesis; 8.1 Introduction 8.2 IR Spectroscopic Methods8.3 NMR Spectroscopic Methods; 9 Polyethyleneglycol ω-Monomethylether (MPEG)-Supported Solution-Phase Synthesis of Oligosaccharides; 9.1 Introduction; 9.2 Polyethyleneglycol ω-Monomethylether (MPEG); 9.3 Linkers; 9.4 MPEG-Supported Syntheses Using Enzymes; 9.5 Use of MPEG in Mechanistic Studies; 9.6 MPEG and Combinatorial Libraries; 9.7 Other Applications; 9.8 Capping; 9.9 Outlook; 10 Two-Direction Glycosylations for the Preparation of Libraries of Oligosaccharides; 10.1 Two-Directional Glycosylations in Solution 10.2 Two-Directional Glycosylations on Solid Support |
Record Nr. | UNINA-9910829966203321 |
New York, : Wiley-Interscience, c2001 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|