Biocalorimetry 2 : applications of calorimetry in the biological sciences / / edited by John E. Ladbury, Michael L. Doyle |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley, c2004 |
Descrizione fisica | 1 online resource (277 p.) |
Disciplina | 572/.43 |
Altri autori (Persone) |
LadburyJohn E. <1960->
DoyleMichael L. <1959-> |
Soggetto topico |
Calorimetry
Biology - Technique |
ISBN |
1-280-27608-8
9786610276080 0-470-01112-2 0-470-01111-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Biocalorimetry 2; Contents; Preface; List of Contributors; Part I General Introduction; 1 Applications of Biocalorimetry: Binding, Stability and Enzyme Kinetics; 1.1 Introduction; 1.2 Principles of isothermal titration calorimetry (ITC); 1.3 Applications of ITC in the life sciences; 1.4 Thermodynamic signatures of non-covalent interactions; 1.5 Thermodynamic discrimination (TD); 1.6 ITC as a tool for studying drug-DNA interactions; 1.7 ITC as a tool for studying protein-DNA interactions; 1.8 The application of calorimetry for examining hydration effcts
1.9 The use of ITC for studying the kinetics and thermodynamics of enzyme catalysis1.10 Principles of differential scanning calorimetry (DSC); 1.11 Applications of DSC in the life sciences; 1.12 Thermodynamic stability; 1.13 Shelf life versus thermodynamic stability; 1.14 Specific and non-specific binding; 1.15 Intrinsic and extrinsic macromolecular stability; 1.16 Oligomerization; 1.17 The use of DSC for examining nucleic acid helix coil transitions; 1.18 Summary; Acknowledgements; References; Part II Isothermal Titration Calorimetry; 2 Isothermal Titration Calorimetry: A Tutorial 2.1 Introduction2.2 Thermodynamic characterization; 2.3 Instrumentation; 2.4 Raw data; 2.5 Basic considerations for experimental set-up; 2.6 Data analysis; 2.7 Summary; Application notes; Acknowledgement; References; 3 The Application of Isothermal Titration Calorimetry to Drug Discovery; 3.1 Introduction; 3.2 Overview of the drug discovery process; 3.3 Experimental measurement of thermodynamic binding parameters; 3.4 ITC in drug discovery; 3.5 Summary; References; 4 Dissecting the Thermodynamics of DNA-Protein Interactions; 4.1 Introduction; 4.2 Model systems 4.3 Comparison with the hydrophobic effect4.4 Protonation and charged-charged hydrogen bonds; 4.5 Dissection of the binding entropy; 4.6 Entropy contributions to the Sso7d-DNA interaction; 4.7 Entropy contributions to the GCN4-DNA interaction; 4.8 Discussion; Acknowledgements; References; 5 Salt Effects in Ribonuclease-Ligand Interactions: Screening or Competitive Binding?; 5.1 Introduction; 5.2 Anion binding to a protein-protein complex; 5.3 Charge-charge interactions in ribonuclease binding; 5.4 Conclusions; Acknowledgement; References 6 Thermodynamics-Structure Correlations of Sulfonamide Inhibitor Binding to Carbonic Anhydrase6.1 Introduction; 6.2 Identification of protonation reactions occurring upon binding; 6.3 Observed thermodynamics of inhibitor binding to CA; 6.4 Energetics of inhibitor protonation; 6.5 Sulfonamide 'anion' binding thermodynamics; 6.6 Correlations between structures and the thermodynamics of sulfonamide binding to CA; 6.7 Conclusions; References; 7 Energetics of the Interaction of Human Acidic Fibroblast Growth Factor with Heparin and the Functional Analogue Myo-Inositol Hexasulfate; 7.1 Introduction 7.2 Thermodynamic parameter derived from ITC experiments |
Altri titoli varianti | Biocalorimetry two |
Record Nr. | UNINA-9910876528003321 |
Chichester ; ; Hoboken, NJ, : Wiley, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Biochemical physics research trends [[electronic resource] /] / Sergei D. Varfolomeev ... [et al.], editors |
Pubbl/distr/stampa | New York, : Nova Science Publishers, 2009 |
Descrizione fisica | 1 online resource (97 p.) |
Disciplina | 572/.43 |
Altri autori (Persone) | VarfolomeevSergeĭ Dmitrievich |
Soggetto topico | Physical biochemistry |
Soggetto genere / forma | Electronic books. |
ISBN | 1-61728-150-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910460028303321 |
New York, : Nova Science Publishers, 2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Biochemical physics research trends [[electronic resource] /] / Sergei D. Varfolomeev ... [et al.], editors |
Pubbl/distr/stampa | New York, : Nova Science Publishers, 2009 |
Descrizione fisica | 1 online resource (97 p.) |
Disciplina | 572/.43 |
Altri autori (Persone) | VarfolomeevSergeĭ Dmitrievich |
Soggetto topico | Physical biochemistry |
ISBN | 1-61728-150-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910785178903321 |
New York, : Nova Science Publishers, 2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Bioenergetics 3 [[electronic resource] /] / David G. Nicholls, Stuart J. Ferguson |
Autore | Nicholls David G |
Edizione | [[3rd ed.].] |
Pubbl/distr/stampa | San Diego, Calif., : Academic Press, c2002 |
Descrizione fisica | 1 online resource (331 p.) |
Disciplina | 572/.43 |
Altri autori (Persone) | FergusonS. J <1949-> (Stuart John) |
Soggetto topico |
Bioenergetics
Biological transport, Active |
Soggetto genere / forma | Electronic books. |
ISBN |
1-281-03340-5
9786611033408 0-08-052793-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Bioenergetics 3; Copyright Page; CONTENTS; Preface; Note to the reader; Glossary; CHAPTER 1. CHEMIOSMOTIC ENERGY TRANSDUCTION; 1.1 Introduction; 1.2 The chemiosmotic theory: fundamentals; 1.3 The basic morphology of energy-transducing membranes; 1.4 Overview; CHAPTER 2. ION TRANSPORT ACROSS ENERGY-CONSERVING MEMBRANES; 2.1 Introduction; 2.2 The classification of ion transport; 2.3 Bilayer-mediated transport; 2.4 Protein-catalysed transport; 2.5 Swelling and the co-ordinate movement of ions across membranes; CHAPTER 3. QUANTITATIVE BIOENERGETICS: THE MEASUREMENT OF DRIVING FORCES
3.1 Introduction3.2 Gibbs energy and displacement from equilibrium; 3.3 Oxidation-reduction (redox) potentials; 3.4 Ion electrochemical potential differences; 3.5 Photons; 3.6 Bioenergetic interconversions and thermodynamic constraints on their stoichiometries; 3.7 The equilibrium distributions of ions, weak acids and weak bases; 3.8 Membrane potentials, diffusion potentials, Donnan potentials and surface potentials; CHAPTER 4. THE CHEMIOSMOTIC PROTON CIRCUIT; 4.1 Introduction; 4.2 The measurement of protonmotive force; 4.3 The stoichiometry of proton extrusion by the respiratory chain 4.4 The stoichiometry of proton uptake by the ATP synthase4.5 Proton current and respiratory control; 4.6 Proton conductance; 4.7 Mitochondria1 respiration rate and metabolic control analysis; 4.8 Overall parameters of energy transduction; 4.9 Reversed electron transfer and the proton circuit driven by ATP hydrolysis; 4.10 ATP synthesis driven by an artificial protonmotive force; 4.11 Kinetic competence of Δp in the proton circuit; 4.12 Light-dependent ATP synthesis by bovine heart ATP synthase; CHAPTER 5. RESPIRATORY CHAINS; 5.1 Introduction 5.2 Components of the mitochondria1 respiratory chain5.3 The sequence of redox carriers in the respiratory chain; 5.4 The mechanism of electron transfer; 5.5 Proton translocation by the respiratory chain: 'loops', ' conformational pumps' or both?; 5.6 Complex I (NADH-UQ oxidoreductase); 5.7 Delivering electrons to ubiquinone without proton translocation; 5.8 Ubiquinone and complex III (bc1 or UQ-CYT c oxidoreductase); 5.9 Cytochrome c and complex IV (cytochrome c oxidase; ferrocytochrome c: O2 oxidoreductase) 5.10 Overall proton and charge movements catalysed by the respiratory chain: correlation with the P/O ratio5.11 Superoxide production by complexes I and III; 5.12 Oxidative stress; 5.13 The nicotinamide nucleotide transhydrogenase; 5.14 Electron transport in mitochondria of non-mammalian cells; 5.15 Bacterial respiratory chains; CHAPTER 6. PHOTOSYNTHETIC GENERATORS OF PROTONMOTIVE FORCE; 6.1 Introduction; 6.2 The light reaction of photosynthesis in Rhodobacter sphaeroides and related organisms; 6.3 The generation by illumination or respiration of Δp in photosynthetic bacteria 6.4 The electron-transfer and light-capture pathway in green plants and algae |
Record Nr. | UNINA-9910457980403321 |
Nicholls David G | ||
San Diego, Calif., : Academic Press, c2002 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Bioenergetics 3 [[electronic resource] /] / David G. Nicholls, Stuart J. Ferguson |
Autore | Nicholls David G |
Edizione | [[3rd ed.].] |
Pubbl/distr/stampa | San Diego, Calif., : Academic Press, c2002 |
Descrizione fisica | 1 online resource (331 p.) |
Disciplina | 572/.43 |
Altri autori (Persone) | FergusonS. J <1949-> (Stuart John) |
Soggetto topico |
Bioenergetics
Biological transport, Active |
ISBN |
1-281-03340-5
9786611033408 0-08-052793-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Bioenergetics 3; Copyright Page; CONTENTS; Preface; Note to the reader; Glossary; CHAPTER 1. CHEMIOSMOTIC ENERGY TRANSDUCTION; 1.1 Introduction; 1.2 The chemiosmotic theory: fundamentals; 1.3 The basic morphology of energy-transducing membranes; 1.4 Overview; CHAPTER 2. ION TRANSPORT ACROSS ENERGY-CONSERVING MEMBRANES; 2.1 Introduction; 2.2 The classification of ion transport; 2.3 Bilayer-mediated transport; 2.4 Protein-catalysed transport; 2.5 Swelling and the co-ordinate movement of ions across membranes; CHAPTER 3. QUANTITATIVE BIOENERGETICS: THE MEASUREMENT OF DRIVING FORCES
3.1 Introduction3.2 Gibbs energy and displacement from equilibrium; 3.3 Oxidation-reduction (redox) potentials; 3.4 Ion electrochemical potential differences; 3.5 Photons; 3.6 Bioenergetic interconversions and thermodynamic constraints on their stoichiometries; 3.7 The equilibrium distributions of ions, weak acids and weak bases; 3.8 Membrane potentials, diffusion potentials, Donnan potentials and surface potentials; CHAPTER 4. THE CHEMIOSMOTIC PROTON CIRCUIT; 4.1 Introduction; 4.2 The measurement of protonmotive force; 4.3 The stoichiometry of proton extrusion by the respiratory chain 4.4 The stoichiometry of proton uptake by the ATP synthase4.5 Proton current and respiratory control; 4.6 Proton conductance; 4.7 Mitochondria1 respiration rate and metabolic control analysis; 4.8 Overall parameters of energy transduction; 4.9 Reversed electron transfer and the proton circuit driven by ATP hydrolysis; 4.10 ATP synthesis driven by an artificial protonmotive force; 4.11 Kinetic competence of Δp in the proton circuit; 4.12 Light-dependent ATP synthesis by bovine heart ATP synthase; CHAPTER 5. RESPIRATORY CHAINS; 5.1 Introduction 5.2 Components of the mitochondria1 respiratory chain5.3 The sequence of redox carriers in the respiratory chain; 5.4 The mechanism of electron transfer; 5.5 Proton translocation by the respiratory chain: 'loops', ' conformational pumps' or both?; 5.6 Complex I (NADH-UQ oxidoreductase); 5.7 Delivering electrons to ubiquinone without proton translocation; 5.8 Ubiquinone and complex III (bc1 or UQ-CYT c oxidoreductase); 5.9 Cytochrome c and complex IV (cytochrome c oxidase; ferrocytochrome c: O2 oxidoreductase) 5.10 Overall proton and charge movements catalysed by the respiratory chain: correlation with the P/O ratio5.11 Superoxide production by complexes I and III; 5.12 Oxidative stress; 5.13 The nicotinamide nucleotide transhydrogenase; 5.14 Electron transport in mitochondria of non-mammalian cells; 5.15 Bacterial respiratory chains; CHAPTER 6. PHOTOSYNTHETIC GENERATORS OF PROTONMOTIVE FORCE; 6.1 Introduction; 6.2 The light reaction of photosynthesis in Rhodobacter sphaeroides and related organisms; 6.3 The generation by illumination or respiration of Δp in photosynthetic bacteria 6.4 The electron-transfer and light-capture pathway in green plants and algae |
Record Nr. | UNINA-9910784528703321 |
Nicholls David G | ||
San Diego, Calif., : Academic Press, c2002 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Biophysical chemistry [[electronic resource] /] / James P. Allen |
Autore | Allen James P |
Pubbl/distr/stampa | Oxford ; ; Hoboken, NJ, : Wiley-Blackwell Pub., 2008 |
Descrizione fisica | 1 online resource (510 p.) |
Disciplina | 572/.43 |
Soggetto topico | Physical biochemistry |
Soggetto genere / forma | Electronic books. |
ISBN |
1-282-03429-4
9786612034299 1-4443-0073-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Basic thermodynamic and biochemical concepts -- Pt. 1. Thermodynamics and kinetics. First law of thermodynamics ; Second law of thermodynamics ; Phase diagrams, mixtures, and chemical potential ; Equilibria and reactions involving protons ; Oxidation/reduction reactions and bioenergetics ; Kinetics and enzymes ; The Boltzmann distribution and statistical thermodynamics -- Pt. 2. Quantum mechanics and spectroscopy. Quantum theory: introduction and principles ; Particle in a box and tunneling ; Vibrational motion and infrared spectroscopy ; Atomic structure: hydrogen atom and multi-electron atoms ; Chemical bonds and protein interactions ; Electronic transitions and optical spectroscopy ; X-ray diffraction and extended x-ray absorption fine structure ; Magnetic resonance -- Pt. 3. Understanding biological systems using physical chemistry. Signal transduction ; Membrane potentials, transporters, and channels ; Molecular imaging ; Photosynthesis -- Answers to problems -- Fundamental constants -- Conversion factors for energy units -- The periodic table. |
Record Nr. | UNINA-9910454263603321 |
Allen James P | ||
Oxford ; ; Hoboken, NJ, : Wiley-Blackwell Pub., 2008 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Energy metabolism and behavior in the corticotropin-releasing factor family of peptides / / edited by James A. Carr and David A. Lovejoy |
Autore | David A. Lovejoy |
Pubbl/distr/stampa | Frontiers Media SA, 2015 |
Descrizione fisica | 1 online resource (114 pages) : illustrations |
Disciplina | 572/.43 |
Collana | Frontiers Research Topics |
Soggetto topico |
Physiology
Human Anatomy & Physiology Health & Biological Sciences |
Soggetto non controllato |
peptide
energy balance evolution Stress food intake |
ISBN | 9782889195374 (ebook) |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910137539103321 |
David A. Lovejoy | ||
Frontiers Media SA, 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Theory and applications of heat transfer in humans / / edited by Devashish Shrivastava |
Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2018] |
Descrizione fisica | 1 online resource (xxxi, 831 pages) |
Disciplina | 572/.43 |
Soggetto topico |
Human physiology
Biophysics Heat - Transmission |
ISBN |
1-119-12732-7
1-119-12731-9 1-119-12742-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910270897203321 |
Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2018] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Theory and applications of heat transfer in humans / / edited by Devashish Shrivastava |
Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2018] |
Descrizione fisica | 1 online resource (xxxi, 831 pages) |
Disciplina | 572/.43 |
Soggetto topico |
Human physiology
Biophysics Heat - Transmission |
ISBN |
1-119-12732-7
1-119-12731-9 1-119-12742-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910817346603321 |
Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2018] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|