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Al cuore della vita : il suicidio cellulare e la morte creatrice / Jean Claude Ameisen ; traduzione di Alessandro Serra
| Al cuore della vita : il suicidio cellulare e la morte creatrice / Jean Claude Ameisen ; traduzione di Alessandro Serra |
| Autore | AMEISEN, Jean-Claude |
| Pubbl/distr/stampa | Milano, : Feltrinelli, 2001 |
| Descrizione fisica | 361 p. ; 22 cm |
| Disciplina | 571.936 |
| Collana | Serie bianca |
| Soggetto topico | Apoptosi |
| ISBN | 88-07-17047-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNISA-990000691900203316 |
AMEISEN, Jean-Claude
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| Milano, : Feltrinelli, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Analytical cellular pathology : journal of the European Society for Analytical Cellular Pathology
| Analytical cellular pathology : journal of the European Society for Analytical Cellular Pathology |
| Pubbl/distr/stampa | Amsterdam, : IOS Press |
| Disciplina |
571.936
611 |
| Soggetto topico |
Pathology, Cellular
Cytology Cells - pathology Cytological Techniques Image Processing, Computer-Assisted Histology Pathology |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1878-3651 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996212441303316 |
| Amsterdam, : IOS Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Analytical cellular pathology : journal of the European Society for Analytical Cellular Pathology
| Analytical cellular pathology : journal of the European Society for Analytical Cellular Pathology |
| Pubbl/distr/stampa | Amsterdam, : IOS Press |
| Disciplina |
571.936
611 |
| Soggetto topico |
Pathology, Cellular
Cytology Cells - pathology Cytological Techniques Image Processing, Computer-Assisted Cytopathologie Cytologie Cytologie - Technique Histology Pathology |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1878-3651 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910146642703321 |
| Amsterdam, : IOS Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anoikis : how the extracellular matrix regulates life-or-death decisions / / edited by Steven M. Frisch
| Anoikis : how the extracellular matrix regulates life-or-death decisions / / edited by Steven M. Frisch |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (210 pages) |
| Disciplina | 571.936 |
| Soggetto topico |
Extracellular matrix
Apoptosis Apoptosi Histologia |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-73856-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Introduction -- Contents -- 1 Metabolic Contributions to Anoikis-Resistance in Metastatic Dissemination -- Abstract -- 1 Introduction -- 2 Bioenergetics -- 2.1 Glycolysis -- 2.2 Glutaminolysis -- 2.3 Autophagy -- 3 Redox Control -- 3.1 Restricted Glucose Oxidation -- 3.2 Antioxidant Defenses -- 3.3 ROS-Mediated Anti-apoptotic Signaling -- 4 Conclusion -- References -- 2 Metabolic Reprogramming and the Control of Anoikis Resistance in Cancer -- Abstract -- 1 Metabolic Signal Integrators -- 1.1 The PI3K/Akt-mTOR Pathway -- 1.2 The Ras-MAPK Pathway -- 1.3 Myc and HIF-1 Transcription Factors -- 1.4 AMPK Pathway -- 2 ECM Attachment-Dependent Signaling Pathways that Regulate Cell Metabolism -- 3 An Overview of Model Systems Used to Study Anoikis -- 4 Metabolic Adaptations of Detached Cancer Cells-Roles in Anoikis-Resistance and Metastasis -- 4.1 Glucose Metabolism -- 4.2 Amino Acid Metabolism -- 4.3 Redox Homeostasis -- 4.3.1 Antioxidant Enzymes in Anoikis-Resistance -- 4.3.2 Mechanisms to Reduce ROS Generation -- 4.3.3 Synthesis of Reducing Equivalents -- 4.3.4 Mitochondrial ROS and Anoikis -- 4.4 Lipid Metabolism -- 5 HIF-1 and Anoikis-Resistance -- 6 Autophagy and Its Role in the Regulation of Metabolic Stress and Anoikis -- 7 Metabolic Switch in Detached Cells-The Tug of War Between AMPK and Akt -- Acknowledgement -- References -- 3 The Intersection of Anoikis Resistance and Fatty Acid Metabolism in Cancer -- Abstract -- 1 Introduction -- 2 Metabolic Plasticity -- 3 Fatty Acid Oxidation -- 4 Stemness and Fatty Acid Oxidation -- 5 FAO in Ovarian Cancer -- 6 FAO-Mediated Signaling and Anoikis Resistance -- 7 Receptor Tyrosine Kinase Contribution to Metabolic Reprogramming -- 8 Conclusions -- References -- 4 Shc and the Control of Small GTPase Dynamics in Cellular Anchorage -- Abstract.
1 Cellular Anchorage and the Importance of Shape Change -- 2 Regulation of Shape Change by Rho GTPases -- 3 Rho GTPases and Abnormal Matrix Signaling in Cancer -- 4 p52Shc and the Control of Mechanical Signals -- 5 Distinct Functional Roles for p66Shc -- 6 Control of RhoA and Anoikis by p66Shc -- 7 p66Shc and Metastatic Behavior -- 8 Epigenetic Control of SHC1 and Implications for Lineage Shifting -- 9 Summary -- References -- 5 Anoikis and the Human Gut Epithelium in Health and Disease -- Abstract -- 1 Anoikis: Back to (General) Basics -- 1.1 A Brief Word on Apoptosis -- 1.2 Cell-ECM and Cell-Cell Interactions -- 1.2.1 Integrins -- 1.2.2 E-cadherin -- 1.3 Enter Anoikis -- 1.3.1 Anoikis and Integrins -- 1.3.2 Anoikis and E-cadherin -- 2 Anoikis and the Human Gut Epithelium in Health -- 2.1 Anoikis and the Renewal of the Human Gut Epithelium -- 2.1.1 A Few Words on the Regulation of hIEC Survival -- 2.1.2 hIEC Anoikis: Sensitivity Versus State of Differentiation -- 2.2 hIEC Anoikis and Integrins -- 2.3 hIEC Anoikis and E-cadherin -- 3 Anoikis and the Human Gut Epithelium in Disease -- 3.1 Anoikis and CRC: Generalities -- 3.1.1 Anoikis, Integrins and CRC -- 3.1.2 Anoikis, E-cadherins and CRC -- 3.2 Anoikis and ... IBD? -- 4 Concluding Considerations -- Acknowledgements -- References -- 6 The Roles of Anoikis in Cervical Cancer -- Abstract -- 1 Introduction -- 2 The Role of Anoikis in Cervical Cancer -- 2.1 Molecular Mechanisms of Anoikis -- 2.2 The Role of Anoikis Resistance in Cervical Cancer Invasion and Metastasis -- 2.3 Molecular Mechanisms of Anoikis Resistance in Cervical Cancer Cells -- 2.4 The Role of Chronic Stress in Cervical Cancer Through Anoikis Resistance -- 3 The Role of YAP Proteins in Cervical Cancer -- 3.1 The Structure and Function of YAP-Related Proteins -- 3.2 Role of YAP Proteins in Cervical Caner. 3.3 YAP Proteins in the Susceptibility to hrHPV Infection -- 3.4 The Role of Chronic Stress in Cervical Cancer Through the Hippo-YAP Pathway -- 4 Conclusions and Future Directions -- References -- 7 Anoikis Resistance in Melanoma -- Abstract -- 1 Introduction -- 2 Epithelial-Mesenchymal Transition (EMT) -- 3 Anoikis-Death Induced in Epithelial Cells upon Detachment from Extra Cellular Matrix (ECM) -- 4 General Pathways Leading to Anoikis Resistance in Epithelial Tissues -- 5 Melanocytes and Melanoma-Non-epithelial Lineage Origins -- 6 Cell Surface Molecules in Anoikis Resistance in Melanoma -- 6.1 Integrin Switch -- 6.2 Fibronectin -- 6.3 Cadherins -- 7 Activation of Receptor Tyrosine Kinases in Melanoma Anoikis Resistance -- 7.1 c-MET/HGF Axis -- 7.2 FGFR1/FGF2 Axis -- 8 Signaling Pathways in Melanoma Anoikis Resistance -- 8.1 Mitogen-Activated Protein Kinase (MAPK) Pathway -- 8.2 Phosphoinositide 3-Kinase (PI3K)/AKT Pathway -- 8.3 CDKN2A and p16INK4A -- 8.4 Focal Adhesion Kinase (FAK) Pathway -- 9 Transcription Factors in Melanoma Anoikis Resistance -- 9.1 STAT3 -- 9.2 FOSL1 -- 9.3 BRN2 -- 10 Anti-apoptotic Mechanisms in Melanoma Anoikis Resistance -- 11 Conclusion -- References -- 8 Anoikis Mediated by Stress-Activated MAPK Signaling Pathways -- Abstract -- 1 Stress-Activated MAPK Signaling Pathways -- 1.1 p38 MAPK -- 1.2 JNK -- 2 Stress-Activated MAPK and Cell Death -- 3 Stress-Activated MAPK and BCL2 Family Proteins -- 4 JNK and Anoikis -- 5 p38 MAPK and Anoikis -- 6 Conclusions -- References -- 9 The TGFβ and Androgen Receptor Signaling Pathways Converge to Support Anoikis Resistance in Triple Negative Breast Cancer -- Abstract -- 1 Introduction -- 2 Anoikis Resistance and Breast Cancer -- 3 The TGFβ Pathway -- 4 TGFβ Signaling in Breast Cancer -- 5 TGFβ Inhibitors in BC Clinical Trials. 6 Connections Between AR and TGFβ in Prostate and Breast Cancer -- 7 TGFβ and AR Pathways Converge to Support TNBC Anoikis Resistance -- References -- 10 Regulation of Homeostasis and Anoikis by Epithelial Cell Extrusion -- Abstract -- 1 Introduction -- 2 Sphingosine-1-Phosphate (S1P) and Collaborating Factors in Cell Extrusion -- 3 Specialized Mechanisms Pertaining to the Extrusion of Transformed Cells -- 4 Summary and Future Directions -- References. |
| Record Nr. | UNINA-9910495350303321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Apoptosis / / edited by Justine Rudner
| Apoptosis / / edited by Justine Rudner |
| Pubbl/distr/stampa | Rijeka, Croatia : , : InTech, , 2013 |
| Descrizione fisica | 1 online resource (204 pages) : illustrations some color |
| Disciplina | 571.936 |
| Soggetto topico | Apoptosis |
| ISBN |
953-51-5371-4
953-51-1133-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910136322603321 |
| Rijeka, Croatia : , : InTech, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Apoptosis / edited by John C. Reed
| Apoptosis / edited by John C. Reed |
| Pubbl/distr/stampa | San Diego : Academic Press, 2000 |
| Descrizione fisica | xxxiii, 569 p. : ill. ; 24 cm |
| Disciplina | 571.936 |
| Altri autori (Persone) | Reed, John C. |
| Collana | Methods in enzymology ; 322 |
| Soggetto topico |
Apoptosis
Morte delle cellule |
| ISBN | 0121822230 (v.322) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991003126379707536 |
| San Diego : Academic Press, 2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Apoptosis : the molecular basis of cell death / edited by L. David Tomei, Frederick O. Cope
| Apoptosis : the molecular basis of cell death / edited by L. David Tomei, Frederick O. Cope |
| Pubbl/distr/stampa | New York, : Cold Spring Harbor Laboratory Press, 1991 |
| Descrizione fisica | IX, 321 p. : ill. ; 23 cm |
| Disciplina | 571.936 |
| Collana | Current comunications in cell & molecular biology |
| Soggetto non controllato | Cellule |
| ISBN | 0-87969-366-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-990001779850403321 |
| New York, : Cold Spring Harbor Laboratory Press, 1991 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Apoptosis : the molecular basis of cell death / edited by L. David Tomei, Frederick O. Cope
| Apoptosis : the molecular basis of cell death / edited by L. David Tomei, Frederick O. Cope |
| Pubbl/distr/stampa | Plainview : Cold Spring Harbor Laboratory Press, 1991 |
| Descrizione fisica | ix, 321 p. : ill. ; 23 cm |
| Disciplina | 571.936 |
| Altri autori (Persone) |
Tomei, L. David
Cope, Frederick O. |
| Collana | Current communications in cell & molecular biology ; 3 |
| Soggetto topico |
Apoptosis
Cell death |
| ISBN | 0879693665 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991000700079707536 |
| Plainview : Cold Spring Harbor Laboratory Press, 1991 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Apoptosis and Human Health: Understanding Mechanistic and Therapeutic Potential / / edited by Kuladip Jana
| Apoptosis and Human Health: Understanding Mechanistic and Therapeutic Potential / / edited by Kuladip Jana |
| Autore | Jana Kuladip |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (461 pages) |
| Disciplina | 571.936 |
| Soggetto topico |
Cell death
Diseases Cytology Cell Death Cell Biology |
| ISBN |
9789819779055
9819779057 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1: Apoptosis: Intricate connections in cell death pathways and disease implications -- Chapter 2: Apoptosis: A Controlled Cell’s Fate -- Chapter 3: Apoptosis: Novel insights into the role of death receptors and caspases in cell fate -- Chapter 4: Apoptosis: Mechanisms and Clinical Implications -- Chapter 5: Apoptosis and Mitochondria: Cell death mechanisms -- Chapter 6: Apoptosis: ER stress and Disease pathology -- Chapter 7: Apoptosis: Oxidative stress and Antioxidants -- Chapter 8: Caspase Independent Apoptosis: New Insights and Current Perspectives -- Chapter 9: Role of Apoptosis in Cancer: Therapeutic targets and strategies -- Chapter 10: Mechanisms of PANoptosis and its implications in cancer progression and treatment -- Chapter 11: Role of Apoptosis in Neurodegeneration: Therapeutic targets and strategies.-b Chapter 12: Role of Apoptosis in Diabetes: Therapeutic targets and strategies -- Chapter 13: Role of Apoptosis in Cardiovascular diseases: Therapeutic targets and strategies -- Chapter 14: Chapter 15: Role of Apoptosis in Parasitic infections: Therapeutic targets and strategies -- Chapter 15: Role of Apoptosis in Viral infections with special reference to Covid 19: Therapeutic targets and strategies -- Chapter 16: Role of Apoptosis in male Infertility: Therapeutic targets and strategies -- Chapter 17: Role of Apoptosis in aging: Therapeutic targets and strategies -- Chapter 18: Apoptosis: Natural product-derived small molecules as Therapeutics -- Chapter 19: Apoptosis-based therapeutics and inhibitors in clinical trials or in preclinical state -- Chapter 20: Apoptosis and cancer immunotherapy: Current mechanisms and emerging strategies. |
| Record Nr. | UNINA-9910918596103321 |
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Jana Kuladip
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Apoptosis and medicine / / edited by Tobias Ntuli
| Apoptosis and medicine / / edited by Tobias Ntuli |
| Pubbl/distr/stampa | [Place of publication not identified] : , : InTech, , [2012] |
| Descrizione fisica | 1 online resource (288 pages) |
| Disciplina | 571.936 |
| Soggetto topico | Apoptosis |
| ISBN | 953-51-5311-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910138347003321 |
| [Place of publication not identified] : , : InTech, , [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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