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Intro -- BASOPHIL GRANULOCYTES -- BASOPHIL GRANULOCYTES -- CONTENTS -- PREFACE -- Chapter 1 NEGATIVE REGULATION OF FC RI-MEDIATED BASOPHIL ACTIVATION BY THE CBL FAMILY OF ADAPTOR PROTEINS -- ABSTRACT -- INTRODUCTION -- The High Affinity Receptor for IgE: Structure and Function. -- Mechanisms Underlying Negative Regulation of Basophil Activation. -- CBL FAMILY PROTEINS -- Domain Structure and Function of Cbl Proteins. -- Fc RI Down-Regulation by Cbl-Mediated Ubiquitination. -- Fc RI Down-Regulation by Cbl Adaptor Function. -- Cbl-Mediated Down-Regulation of Non-Receptor PTKs Upon Fc RI Engagement. -- Cbl-Mediated Regulation of PTKs in Unstimulated Basophils. -- CONCLUSION -- REFERENCES -- Chapter 2 BASOPHILS, MAST CELLS AND LIVER CANCER -- ABSTRACT -- INTRODUCTION -- Liver Cancer: A Still Complex Disease -- Mast Cells: A Heterogeneous Cell Population -- Human Basophils Granulocytes: A Rare But Emerging Inflammatory Cell Population -- Mast Cells, Basophil Granulocytes and the Liver Cancer -- CONCLUSIONS -- REFERENCES -- Chapter 3 BASOPHILIC GRANULOCYTE: A REVIEW OF ITS CHARACTERISTICS AND ROLES -- ABSTRACT -- INTRODUCTION -- Phenotype, Development, and Activation of Basophils -- Basophils and Anaphylaxis -- (1) Classical pathway of anaphylaxis by mast cells and IgE -- (2) A new anaphylaxis pathway that involves basophils and IgG -- (3) Platelet-activating factor and basophil-mediated anaphylaxis -- (4) The role of basophils in human anaphylaxis -- Roles of Basophils in Chronic Allergic Reactions -- (1) Roles of IgE in the chronic allergic reaction -- (2) The role of basophils in the IgE-dependent chronic allergic inflammatory response -- (3) Basophils as potential therapeutic targets for chronic allergic inflammation -- The Role of Basophils in the Control of T Cell Differentiation -- (1) T cell development and IL-4.
(2) The roles of basophils in Th2 cell development -- Roles of Basophils in Immunological Memory Responses -- REFERENCES -- Chapter 4 FLAVONOIDS, NATURAL INHIBITORS OF BASOPHIL ACTIVATION -- ABSTRACT -- INTRODUCTION -- I. Flavonoids Inhibit IL-4, IL-13 and CD40 Ligand Expression by Basophils -- II. Clinical Effects of Flavonoids Identified with in Vivo Animal Models -- III. Flavonoids Ameliorated Ocular Symptoms of Japanese Cedar Pollinosis -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5 BASOPHIL IN TROPICAL INFECTIONS -- ABSTRACT -- INTRODUCTION -- BASOPHIL IN MALARIA -- BASOPHIL IN DENGUE -- BASOPHIL IN TUBERCULOSIS -- BASOPHIL IN LEPROSY -- REFERENCES -- Chapter 6 RESEARCH ON BASOPHIL IN THAILAND -- ABSTRACT -- INTRODUCTION -- BASOPHIL IN ALLERGY -- BASOPHIL IN CANCER -- BASOPHIL IN INFECTION -- BASOPHIL IN INTOXICATION -- WHAT SHOULD THE NEXT TREND OF RESEARCH IN THAILAND BE? -- REFERENCES -- Chapter 7 BASOPHIL GRANULOCYTES: SMALL IN NUMBERS, MIGHTY IN IMMUNE REGULATION* -- REFERENCES -- Chapter 8 C-REACTIVE PROTEIN: FCR RECEPTOR-MEDIATED EFFECTS ON HUMAN PERIPHERAL BLOOD BASOPHILS IN VITRO* -- INTRODUCTION -- MATERIALS AND METHODS -- Basophils Isolation -- Reagents -- Cell Incubations and Assessment of Basophil Response -- Basophil Desensitizsation and Restimulation in Vitro -- STATISTICAL ANALYSIS -- RESULTS AND DISCUSSION -- Basophil Responses to Human Aggregated IgG, C-Reactive Protein, and Fcgriii Cross-Linking -- 2. Basophil Responses to Cholinergic Drugs -- 3. Basophil Responses to Aggregated IgG and Cholinergic Drugs -- 4. Basophil Responses to Human C-Reactive Protein and Cholinergic Drugs -- 5. Joint Effects of CRP with aIigG and Antibody to CD16 -- 6. Normal Human Blood Basophil Responses to Repeated Activation in Vitro -- ACKNOWLEDGMENT -- REFERENCES -- INDEX -- Blank Page.
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Basophil granulocytes [[electronic resource] /] / Paul K. Vellis, editor
