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Calcium signaling [[electronic resource] /] / Masayoshi Yamaguchi, editor
Calcium signaling [[electronic resource] /] / Masayoshi Yamaguchi, editor
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, c2012
Descrizione fisica 1 online resource (247 p.)
Disciplina 571.7/4
Altri autori (Persone) YamaguchiMasayoshi <1947->
Collana Protein biochemistry, synthesis, structure and cellular functions
Soggetto topico Cellular signal transduction
Intracellular calcium
Soggetto genere / forma Electronic books.
ISBN 1-62081-917-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Ca2+ signaling in lower eukaryote / I.V. Shemarova -- Role of calcium in stress mediated signaling in plants / Cheshta Sharma, Amita Pandey, Girdhar K. Pandey -- Calmodulin signaling inside-out : intracellular and extracellular calmodulin and its interaction with a matricellular cysteine-rich calmodulin-binding protein / Danton H. O'Day, Robert Huber, Andres Suarez -- A tale of three proteins : the nucleolar calmodulin-binding protein nucleomorphin and its binding partners calcium-binding protein 4a and puromycin-sensitive aminopeptidase / Danton H. O'Day, Andrew Catalano, Yekaterina Poloz -- Insights into the role of intracellular Ca2+ concentration changes during in vitro chondrogenesis / Csaba Matta ... [et al.] -- Cav2.1 channelopathies and mouse genetic approaches for investigating Cav2.1 channel function and dysfunction / Eiki Takahashi -- Regucalcin : role as a suppressor protein in calcium signaling / Masayoshi Yamaguchi -- Calcium ([Ca2+]i) signaling as a key-target for cancer treatment / Ana-Maria Florea, Dietrich Büsselberg.
Record Nr. UNINA-9910453241403321
Hauppauge, N.Y., : Nova Science Publishers, c2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Calcium signaling [[electronic resource] /] / Masayoshi Yamaguchi, editor
Calcium signaling [[electronic resource] /] / Masayoshi Yamaguchi, editor
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, c2012
Descrizione fisica 1 online resource (247 p.)
Disciplina 571.7/4
Altri autori (Persone) YamaguchiMasayoshi <1947->
Collana Protein biochemistry, synthesis, structure and cellular functions
Soggetto topico Cellular signal transduction
Intracellular calcium
ISBN 1-62081-917-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Ca2+ signaling in lower eukaryote / I.V. Shemarova -- Role of calcium in stress mediated signaling in plants / Cheshta Sharma, Amita Pandey, Girdhar K. Pandey -- Calmodulin signaling inside-out : intracellular and extracellular calmodulin and its interaction with a matricellular cysteine-rich calmodulin-binding protein / Danton H. O'Day, Robert Huber, Andres Suarez -- A tale of three proteins : the nucleolar calmodulin-binding protein nucleomorphin and its binding partners calcium-binding protein 4a and puromycin-sensitive aminopeptidase / Danton H. O'Day, Andrew Catalano, Yekaterina Poloz -- Insights into the role of intracellular Ca2+ concentration changes during in vitro chondrogenesis / Csaba Matta ... [et al.] -- Cav2.1 channelopathies and mouse genetic approaches for investigating Cav2.1 channel function and dysfunction / Eiki Takahashi -- Regucalcin : role as a suppressor protein in calcium signaling / Masayoshi Yamaguchi -- Calcium ([Ca2+]i) signaling as a key-target for cancer treatment / Ana-Maria Florea, Dietrich Büsselberg.
Record Nr. UNINA-9910779604403321
Hauppauge, N.Y., : Nova Science Publishers, c2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Calcium signaling [[electronic resource] /] / Masayoshi Yamaguchi, editor
Calcium signaling [[electronic resource] /] / Masayoshi Yamaguchi, editor
Edizione [1st ed.]
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, c2012
Descrizione fisica 1 online resource (247 p.)
Disciplina 571.7/4
Altri autori (Persone) YamaguchiMasayoshi <1947->
Collana Protein biochemistry, synthesis, structure and cellular functions
Soggetto topico Cellular signal transduction
Intracellular calcium
ISBN 1-62081-917-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Ca2+ signaling in lower eukaryote / I.V. Shemarova -- Role of calcium in stress mediated signaling in plants / Cheshta Sharma, Amita Pandey, Girdhar K. Pandey -- Calmodulin signaling inside-out : intracellular and extracellular calmodulin and its interaction with a matricellular cysteine-rich calmodulin-binding protein / Danton H. O'Day, Robert Huber, Andres Suarez -- A tale of three proteins : the nucleolar calmodulin-binding protein nucleomorphin and its binding partners calcium-binding protein 4a and puromycin-sensitive aminopeptidase / Danton H. O'Day, Andrew Catalano, Yekaterina Poloz -- Insights into the role of intracellular Ca2+ concentration changes during in vitro chondrogenesis / Csaba Matta ... [et al.] -- Cav2.1 channelopathies and mouse genetic approaches for investigating Cav2.1 channel function and dysfunction / Eiki Takahashi -- Regucalcin : role as a suppressor protein in calcium signaling / Masayoshi Yamaguchi -- Calcium ([Ca2+]i) signaling as a key-target for cancer treatment / Ana-Maria Florea, Dietrich Büsselberg.
Record Nr. UNINA-9910827418903321
Hauppauge, N.Y., : Nova Science Publishers, c2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cyclic nucleotide signaling / / edited by Xiaodong Cheng
Cyclic nucleotide signaling / / edited by Xiaodong Cheng
Pubbl/distr/stampa Boca Raton, Florida : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (282 p.)
Disciplina 571.7/4
Collana Methods in Signal Transduction Series
Soggetto topico Cyclic nucleotides
ISBN 0-429-16192-1
1-4822-3557-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Contents; Series Preface; Preface; Editor; Contributors; Chapter 1: Discovery of Small Molecule EPAC Specific Modulators by High-Throughput Screening; Chapter 2: Cyclic Nucleotide Analogs as Pharmacological Tools for Studying Signaling Pathways; Chapter 3: High-Throughput FRET Assays for Fast Time-Dependent Detection of Cyclic AMP in Pancreatic β Cells; Chapter 4: Assessing Cyclic Nucleotide Recognition in Cells : Opportunities and Pitfalls for Selective Receptor Activation; Chapter 5: Monitoring Cyclic Nucleotides Using Genetically Encoded Fluorescent Reporters
Chapter 6: Structural Characterization of Epac by X-Ray CrystallographyChapter 7: Sensory Neuron cAMP Signaling in Chronic Pain; Chapter 8: Monitoring Real-Time Cyclic Nucleotide Dynamics in Subcellular Microdomains; Chapter 9: Identifying Complexes of Adenylyl Cyclase with A-Kinase Anchoring Proteins; Chapter 10: Assessing Cyclic Nucleotide Binding Domain Allostery and Dynamics by NMR Spectroscopy; Chapter 11: A Protocol for Expression and Purification of Cyclic Nucleotide-Free Protein in Escherichia coli; Chapter 12: Cyclic Nucleotide Analogues as Chemical Tools for Interaction Analysis
Chapter 13: Dissecting the Physiological Functions of PKA Using Genetically Modified MiceBack Cover
Record Nr. UNINA-9910797267703321
Boca Raton, Florida : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cyclic nucleotide signaling / / edited by Xiaodong Cheng
Cyclic nucleotide signaling / / edited by Xiaodong Cheng
Pubbl/distr/stampa Boca Raton, Florida : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (282 p.)
Disciplina 571.7/4
Collana Methods in Signal Transduction Series
Soggetto topico Cyclic nucleotides
ISBN 0-429-16192-1
1-4822-3557-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Contents; Series Preface; Preface; Editor; Contributors; Chapter 1: Discovery of Small Molecule EPAC Specific Modulators by High-Throughput Screening; Chapter 2: Cyclic Nucleotide Analogs as Pharmacological Tools for Studying Signaling Pathways; Chapter 3: High-Throughput FRET Assays for Fast Time-Dependent Detection of Cyclic AMP in Pancreatic β Cells; Chapter 4: Assessing Cyclic Nucleotide Recognition in Cells : Opportunities and Pitfalls for Selective Receptor Activation; Chapter 5: Monitoring Cyclic Nucleotides Using Genetically Encoded Fluorescent Reporters
Chapter 6: Structural Characterization of Epac by X-Ray CrystallographyChapter 7: Sensory Neuron cAMP Signaling in Chronic Pain; Chapter 8: Monitoring Real-Time Cyclic Nucleotide Dynamics in Subcellular Microdomains; Chapter 9: Identifying Complexes of Adenylyl Cyclase with A-Kinase Anchoring Proteins; Chapter 10: Assessing Cyclic Nucleotide Binding Domain Allostery and Dynamics by NMR Spectroscopy; Chapter 11: A Protocol for Expression and Purification of Cyclic Nucleotide-Free Protein in Escherichia coli; Chapter 12: Cyclic Nucleotide Analogues as Chemical Tools for Interaction Analysis
Chapter 13: Dissecting the Physiological Functions of PKA Using Genetically Modified MiceBack Cover
Record Nr. UNINA-9910800162803321
Boca Raton, Florida : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cyclic nucleotide signaling / / edited by Xiaodong Cheng
Cyclic nucleotide signaling / / edited by Xiaodong Cheng
Edizione [1st ed.]
Pubbl/distr/stampa Boca Raton, Florida : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (282 p.)
Disciplina 571.7/4
Collana Methods in Signal Transduction Series
Soggetto topico Cyclic nucleotides
ISBN 0-429-16192-1
1-4822-3557-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Contents; Series Preface; Preface; Editor; Contributors; Chapter 1: Discovery of Small Molecule EPAC Specific Modulators by High-Throughput Screening; Chapter 2: Cyclic Nucleotide Analogs as Pharmacological Tools for Studying Signaling Pathways; Chapter 3: High-Throughput FRET Assays for Fast Time-Dependent Detection of Cyclic AMP in Pancreatic β Cells; Chapter 4: Assessing Cyclic Nucleotide Recognition in Cells : Opportunities and Pitfalls for Selective Receptor Activation; Chapter 5: Monitoring Cyclic Nucleotides Using Genetically Encoded Fluorescent Reporters
Chapter 6: Structural Characterization of Epac by X-Ray CrystallographyChapter 7: Sensory Neuron cAMP Signaling in Chronic Pain; Chapter 8: Monitoring Real-Time Cyclic Nucleotide Dynamics in Subcellular Microdomains; Chapter 9: Identifying Complexes of Adenylyl Cyclase with A-Kinase Anchoring Proteins; Chapter 10: Assessing Cyclic Nucleotide Binding Domain Allostery and Dynamics by NMR Spectroscopy; Chapter 11: A Protocol for Expression and Purification of Cyclic Nucleotide-Free Protein in Escherichia coli; Chapter 12: Cyclic Nucleotide Analogues as Chemical Tools for Interaction Analysis
Chapter 13: Dissecting the Physiological Functions of PKA Using Genetically Modified MiceBack Cover
Record Nr. UNINA-9910821911303321
Boca Raton, Florida : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Exosomes : biogenesis, therapeutic applications and emerging research / / Armando Meyer, editor
Exosomes : biogenesis, therapeutic applications and emerging research / / Armando Meyer, editor
Pubbl/distr/stampa New York, [New York] : , : Nova Biomedical, , 2016
Descrizione fisica 1 online resource (121 pages) : illustrations (some color)
Disciplina 571.7/4
Collana Cell Biology Research Progress
Soggetto topico Cell interaction
Cellular signal transduction
ISBN 1-63485-716-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910136574503321
New York, [New York] : , : Nova Biomedical, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Lysophospholipid receptors [[electronic resource] ] : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Lysophospholipid receptors [[electronic resource] ] : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley, c2013
Descrizione fisica 1 online resource (813 p.)
Disciplina 571.7/4
Altri autori (Persone) ChunJerold <1959->
Soggetto topico Cell receptors - Physiology
Cell receptors - Metabolism
Cellular signal transduction - Physiology
ISBN 1-118-53142-6
1-118-53135-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title page; Copyright page; Contents; Preface; Contributors; CHAPTER 1: Lysophosphatidic Acid (LPA) Receptor Signaling; 1.1. Introduction; 1.2. LPA Metabolism; 1.3. Autotaxin; 1.4. LPA Receptors; 1.4.1. LPA1; 1.4.2. LPA2; 1.4.3. LPA3; 1.4.4. LPA4; 1.4.5. LPA5; 1.4.6. LPA6; 1.5. LPA Receptor Agonists and Antagonists; References; CHAPTER 2: Sphingosine 1-Phosphate (S1P) Receptors; 2.1. Introduction; 2.2. S1P Metabolism/Enzyme, and Transport; 2.2.1. S1P Metabolism and Enzymes; 2.2.2. Sphingosine Kinases; 2.2.3. S1P Phosphatases and S1P Lyase
2.3. S1P Receptor Subtypes, and Physiological Functions2.3.1. S1P1; 2.3.2. S1P2; 2.3.3. S1P3; 2.3.4. S1P4; 2.3.5. S1P5; 2.4. Concluding Remarks; References; CHAPTER 3: Global Gene Expression Program of Lysophosphatidic Acid (LPA)-Stimulated Fibroblasts; 3.1. Introduction; 3.2. The Global Transcriptional Response of MEFs to LPA; 3.3. Upregulated Genes; 3.4. Downregulated Genes; 3.5. Induction of Genes that Encode Secreted Factors; 3.6. Overlap between the Expression Profiles of LPA and EGF; 3.7. Conclusions; Acknowledgments; References
CHAPTER 4: Identification of Direct Intracellular Targets of Sphingosine 1-Phosphate (S1P)4.1. Introduction; 4.2. Intracellular Targets for S1P; 4.3. Methods to Identify Intracellular S1P Targets; 4.3.1. S1P Immobilized on Agarose Beads; 4.3.2. Binding of 32P-Labeled S1P to Targets; 4.3.3. Mass Measurement of Endogenous S1P in Immunoprecipitates of Target Proteins; 4.4. Other Potentially Useful Methods to Identify Lipid Binding Proteins; 4.4.1. Lipid Strips for Identification of Binding Proteins (Protein-Lipid Overlay)
4.4.2. Detection of Lipid Binding Proteins by Enzyme-Linked Immunadsorbent Assays4.4.3. Liposome Pull Down; 4.5. Concluding Remarks; Acknowledgments; References; CHAPTER 5: Lysophospholipid Receptor Signaling Platforms: The Receptor Tyrosine Kinase-G Protein-Coupled Receptor Signaling Complex; 5.1. Introduction; 5.2. Lysophospholipid Receptor-Receptor Tyrosine Kinase Complexes; 5.3. Other Lysophospholipid Receptor Signaling Platforms; 5.4. Other Examples of RTK-GPCR Signaling Platforms
5.5. Interaction of RGS Proteins with Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes5.6. S1P and RTK Transactivation; 5.7. Approaches for the Study of Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes; 5.8. Some Useful Protocols for Studying RTK-Lysophospholipid Receptor Signaling Platforms; 5.8.1. Compounds; 5.8.2. Cells; 5.8.3. Immunoprecipitation; 5.8.4. Immunofluorescence; 5.8.5. GTP-γ-S Binding Assay; 5.8.6. Cell Migration; 5.9. Conclusion; Acknowledgment; References
CHAPTER 6: Autotaxin: A Unique Ecto-Type Pyrophosphodiesterase with Diverse Functions
Record Nr. UNINA-9910141615303321
Hoboken, N.J., : Wiley, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Lysophospholipid receptors : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Lysophospholipid receptors : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley, c2013
Descrizione fisica 1 online resource (813 p.)
Disciplina 571.7/4
Altri autori (Persone) ChunJerold <1959->
Soggetto topico Cell receptors - Physiology
Cell receptors - Metabolism
Cellular signal transduction - Physiology
ISBN 1-118-53142-6
1-118-53135-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title page; Copyright page; Contents; Preface; Contributors; CHAPTER 1: Lysophosphatidic Acid (LPA) Receptor Signaling; 1.1. Introduction; 1.2. LPA Metabolism; 1.3. Autotaxin; 1.4. LPA Receptors; 1.4.1. LPA1; 1.4.2. LPA2; 1.4.3. LPA3; 1.4.4. LPA4; 1.4.5. LPA5; 1.4.6. LPA6; 1.5. LPA Receptor Agonists and Antagonists; References; CHAPTER 2: Sphingosine 1-Phosphate (S1P) Receptors; 2.1. Introduction; 2.2. S1P Metabolism/Enzyme, and Transport; 2.2.1. S1P Metabolism and Enzymes; 2.2.2. Sphingosine Kinases; 2.2.3. S1P Phosphatases and S1P Lyase
2.3. S1P Receptor Subtypes, and Physiological Functions2.3.1. S1P1; 2.3.2. S1P2; 2.3.3. S1P3; 2.3.4. S1P4; 2.3.5. S1P5; 2.4. Concluding Remarks; References; CHAPTER 3: Global Gene Expression Program of Lysophosphatidic Acid (LPA)-Stimulated Fibroblasts; 3.1. Introduction; 3.2. The Global Transcriptional Response of MEFs to LPA; 3.3. Upregulated Genes; 3.4. Downregulated Genes; 3.5. Induction of Genes that Encode Secreted Factors; 3.6. Overlap between the Expression Profiles of LPA and EGF; 3.7. Conclusions; Acknowledgments; References
CHAPTER 4: Identification of Direct Intracellular Targets of Sphingosine 1-Phosphate (S1P)4.1. Introduction; 4.2. Intracellular Targets for S1P; 4.3. Methods to Identify Intracellular S1P Targets; 4.3.1. S1P Immobilized on Agarose Beads; 4.3.2. Binding of 32P-Labeled S1P to Targets; 4.3.3. Mass Measurement of Endogenous S1P in Immunoprecipitates of Target Proteins; 4.4. Other Potentially Useful Methods to Identify Lipid Binding Proteins; 4.4.1. Lipid Strips for Identification of Binding Proteins (Protein-Lipid Overlay)
4.4.2. Detection of Lipid Binding Proteins by Enzyme-Linked Immunadsorbent Assays4.4.3. Liposome Pull Down; 4.5. Concluding Remarks; Acknowledgments; References; CHAPTER 5: Lysophospholipid Receptor Signaling Platforms: The Receptor Tyrosine Kinase-G Protein-Coupled Receptor Signaling Complex; 5.1. Introduction; 5.2. Lysophospholipid Receptor-Receptor Tyrosine Kinase Complexes; 5.3. Other Lysophospholipid Receptor Signaling Platforms; 5.4. Other Examples of RTK-GPCR Signaling Platforms
5.5. Interaction of RGS Proteins with Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes5.6. S1P and RTK Transactivation; 5.7. Approaches for the Study of Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes; 5.8. Some Useful Protocols for Studying RTK-Lysophospholipid Receptor Signaling Platforms; 5.8.1. Compounds; 5.8.2. Cells; 5.8.3. Immunoprecipitation; 5.8.4. Immunofluorescence; 5.8.5. GTP-γ-S Binding Assay; 5.8.6. Cell Migration; 5.9. Conclusion; Acknowledgment; References
CHAPTER 6: Autotaxin: A Unique Ecto-Type Pyrophosphodiesterase with Diverse Functions
Record Nr. UNINA-9910808700503321
Hoboken, N.J., : Wiley, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui