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Endoplasmic reticulcum and its role in tumor immunity [[electronic resource] /] / edited by: Paul Eggleton, Marek Michalak and Edwin Bremer
| Endoplasmic reticulcum and its role in tumor immunity [[electronic resource] /] / edited by: Paul Eggleton, Marek Michalak and Edwin Bremer |
| Pubbl/distr/stampa | Frontiers Media SA, 2016 |
| Descrizione fisica | 1 online resource (101 pages) : illustrations; digital, PDF file(s) |
| Disciplina | 571.6/5 |
| Collana |
Frontiers Research Topics
Frontiers in Oncology |
| Soggetto topico |
Endoplasmic reticulum
Tumors - Immunological aspects Immunology Oncology Endoplasmic Reticulum Stress |
| Soggetto non controllato |
Autoimmunity
Angiogenesis T-cell receptors genome damage phage display Aminopeptidases Grp170 Oxidoreductases Vaccines chaperones |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910136799903321 |
| Frontiers Media SA, 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular chaperones of the endoplasmic reticulum [[electronic resource] /] / Martin Schröder
| Molecular chaperones of the endoplasmic reticulum [[electronic resource] /] / Martin Schröder |
| Autore | Schröder Martin <1954-> |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, Inc., c2010 |
| Descrizione fisica | 1 online resource (136 p.) |
| Disciplina | 571.6/5 |
| Collana | Protein science and engineering |
| Soggetto topico |
Molecular chaperones
Endoplasmic reticulum |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61668-459-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Physicochemical principles governing protein folding -- The ER -- Molecular chaperones of the ER. |
| Record Nr. | UNINA-9910452916803321 |
Schröder Martin <1954->
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| New York, : Nova Science Publishers, Inc., c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular chaperones of the endoplasmic reticulum [[electronic resource] /] / Martin Schröder
| Molecular chaperones of the endoplasmic reticulum [[electronic resource] /] / Martin Schröder |
| Autore | Schröder Martin <1954-> |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, Inc., c2010 |
| Descrizione fisica | 1 online resource (136 p.) |
| Disciplina | 571.6/5 |
| Collana | Protein science and engineering |
| Soggetto topico |
Molecular chaperones
Endoplasmic reticulum |
| ISBN | 1-61668-459-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Physicochemical principles governing protein folding -- The ER -- Molecular chaperones of the ER. |
| Record Nr. | UNINA-9910779795003321 |
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Schröder Martin <1954->
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| New York, : Nova Science Publishers, Inc., c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular chaperones of the endoplasmic reticulum [[electronic resource] /] / Martin Schröder
| Molecular chaperones of the endoplasmic reticulum [[electronic resource] /] / Martin Schröder |
| Autore | Schröder Martin <1954-> |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, Inc., c2010 |
| Descrizione fisica | 1 online resource (136 p.) |
| Disciplina | 571.6/5 |
| Collana | Protein science and engineering |
| Soggetto topico |
Molecular chaperones
Endoplasmic reticulum |
| ISBN | 1-61668-459-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Physicochemical principles governing protein folding -- The ER -- Molecular chaperones of the ER. |
| Record Nr. | UNINA-9910826674403321 |
|
Schröder Martin <1954->
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| New York, : Nova Science Publishers, Inc., c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Role of the sarcoplasmic reticulum in smooth muscle [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode]
| Role of the sarcoplasmic reticulum in smooth muscle [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 2002 |
| Descrizione fisica | 1 online resource (297 p.) |
| Disciplina |
571.6/5
611.0186 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Smooth muscle
Sarcoplasmic reticulum |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-26991-X
9786610269914 0-470-66848-2 0-470-85293-3 0-470-85305-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ROLE OF THE SARCOPLASMIC RETICULUM IN SMOOTH MUSCLE; Contents; Participants; Chair's introduction; Role of the sarcoplasmic reticulum in uterine smooth muscle; Discussion; Relationship between the sarcoplasmic reticulum and the plasma membrane; Discussion; General discussion I The role of calmodulin in smooth muscle contraction; Ca(2+) signalling and Ca(2+)-activated K(+) channels in smooth muscle; Discussion; Additional fluxes of activator Ca(2+) accompanying Ca(2+) release from the sarcoplasmic reticulum triggered by InsP(3)-mobilizing agonists; Discussion
Molecular candidates for capacitative and non-capacitative Ca(2+) entry in smooth muscleRegulation of Ca(2+) entry pathways by both limbs of the phosphoinositide pathway; Discussion; Calcium release by ryanodine receptors in smooth muscle; Discussion; Organization of Ca(2+) stores in vascular smooth muscle: functional implications; Discussion; Molecular basis and physiological functions of dynamic Ca(2+) signalling in smooth muscle cells; Discussion; Calcium release events in excitation-contraction coupling in smooth muscle; Discussion Sarcoplasmic reticulum, calcium waves and myometrial signallingDiscussion; Sarcoplasmic reticulum and membrane currents; Discussion; Sarcoplasmic reticulum function and contractile consequences in ureteric smooth muscles; Discussion; General discussion II The physiological significance of smooth muscle Ca(2+) stores; The sarcoplasmic reticulum and smooth muscle function: evidence from transgenic mice; Discussion; The sarcoplasmic reticulum in disease and smooth muscle dysfunction: therapeutic potential; Discussion; The sarcoplasmic reticulum: then and now; Discussion; Final general discussion Index of contributorsSubject index |
| Record Nr. | UNINA-9910143168203321 |
| Chichester ; ; New York, : J. Wiley, 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Role of the sarcoplasmic reticulum in smooth muscle [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode]
| Role of the sarcoplasmic reticulum in smooth muscle [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 2002 |
| Descrizione fisica | 1 online resource (297 p.) |
| Disciplina |
571.6/5
611.0186 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Smooth muscle
Sarcoplasmic reticulum |
| ISBN |
1-280-26991-X
9786610269914 0-470-66848-2 0-470-85293-3 0-470-85305-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ROLE OF THE SARCOPLASMIC RETICULUM IN SMOOTH MUSCLE; Contents; Participants; Chair's introduction; Role of the sarcoplasmic reticulum in uterine smooth muscle; Discussion; Relationship between the sarcoplasmic reticulum and the plasma membrane; Discussion; General discussion I The role of calmodulin in smooth muscle contraction; Ca(2+) signalling and Ca(2+)-activated K(+) channels in smooth muscle; Discussion; Additional fluxes of activator Ca(2+) accompanying Ca(2+) release from the sarcoplasmic reticulum triggered by InsP(3)-mobilizing agonists; Discussion
Molecular candidates for capacitative and non-capacitative Ca(2+) entry in smooth muscleRegulation of Ca(2+) entry pathways by both limbs of the phosphoinositide pathway; Discussion; Calcium release by ryanodine receptors in smooth muscle; Discussion; Organization of Ca(2+) stores in vascular smooth muscle: functional implications; Discussion; Molecular basis and physiological functions of dynamic Ca(2+) signalling in smooth muscle cells; Discussion; Calcium release events in excitation-contraction coupling in smooth muscle; Discussion Sarcoplasmic reticulum, calcium waves and myometrial signallingDiscussion; Sarcoplasmic reticulum and membrane currents; Discussion; Sarcoplasmic reticulum function and contractile consequences in ureteric smooth muscles; Discussion; General discussion II The physiological significance of smooth muscle Ca(2+) stores; The sarcoplasmic reticulum and smooth muscle function: evidence from transgenic mice; Discussion; The sarcoplasmic reticulum in disease and smooth muscle dysfunction: therapeutic potential; Discussion; The sarcoplasmic reticulum: then and now; Discussion; Final general discussion Index of contributorsSubject index |
| Record Nr. | UNINA-9910831187103321 |
| Chichester ; ; New York, : J. Wiley, 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Role of the sarcoplasmic reticulum in smooth muscle / / [editors, Derek J. Chadwick and Jamie A. Goode]
| Role of the sarcoplasmic reticulum in smooth muscle / / [editors, Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 2002 |
| Descrizione fisica | 1 online resource (297 p.) |
| Disciplina |
571.6/5
611.0186 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Smooth muscle
Sarcoplasmic reticulum |
| ISBN |
1-280-26991-X
9786610269914 0-470-66848-2 0-470-85293-3 0-470-85305-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ROLE OF THE SARCOPLASMIC RETICULUM IN SMOOTH MUSCLE; Contents; Participants; Chair's introduction; Role of the sarcoplasmic reticulum in uterine smooth muscle; Discussion; Relationship between the sarcoplasmic reticulum and the plasma membrane; Discussion; General discussion I The role of calmodulin in smooth muscle contraction; Ca(2+) signalling and Ca(2+)-activated K(+) channels in smooth muscle; Discussion; Additional fluxes of activator Ca(2+) accompanying Ca(2+) release from the sarcoplasmic reticulum triggered by InsP(3)-mobilizing agonists; Discussion
Molecular candidates for capacitative and non-capacitative Ca(2+) entry in smooth muscleRegulation of Ca(2+) entry pathways by both limbs of the phosphoinositide pathway; Discussion; Calcium release by ryanodine receptors in smooth muscle; Discussion; Organization of Ca(2+) stores in vascular smooth muscle: functional implications; Discussion; Molecular basis and physiological functions of dynamic Ca(2+) signalling in smooth muscle cells; Discussion; Calcium release events in excitation-contraction coupling in smooth muscle; Discussion Sarcoplasmic reticulum, calcium waves and myometrial signallingDiscussion; Sarcoplasmic reticulum and membrane currents; Discussion; Sarcoplasmic reticulum function and contractile consequences in ureteric smooth muscles; Discussion; General discussion II The physiological significance of smooth muscle Ca(2+) stores; The sarcoplasmic reticulum and smooth muscle function: evidence from transgenic mice; Discussion; The sarcoplasmic reticulum in disease and smooth muscle dysfunction: therapeutic potential; Discussion; The sarcoplasmic reticulum: then and now; Discussion; Final general discussion Index of contributorsSubject index |
| Record Nr. | UNINA-9910877803303321 |
| Chichester ; ; New York, : J. Wiley, 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Subcellular fractionation [[electronic resource] ] : a practical approach / / edited by J.M. Graham and D. Rickwood
| Subcellular fractionation [[electronic resource] ] : a practical approach / / edited by J.M. Graham and D. Rickwood |
| Pubbl/distr/stampa | Oxford ; ; New York, : IRL Press at Oxford University Press, c1997 |
| Descrizione fisica | 1 online resource (360 p.) |
| Disciplina | 571.6/5 |
| Altri autori (Persone) |
GrahamJ. M <1943-> (John M.)
RickwoodD (David) |
| Collana | The practical approach series |
| Soggetto topico | Subcellular fractionation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-66474-7
0-19-159161-0 0-585-48392-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; List of contributors; Abbreviations; 1. Homogenization of tissues and cells; 1. Introduction; 2. Aims of the homogenization procedure; 3. Influence of sample type; 4. Homogenization media; 5. Methods of homogenization; Type 1 homogenizers; Type 2 homogenizers; 6. Homogenization of tissues and cells; Mammalian liver; Brain; Muscle; Mammalian tissue culture cells; Plant organelles; Yeast; Other fungi and algae; Trypanosomes; Bacteria; References; 2. Isolation of subcellular fractions; 1. Introduction; 2. Composition of a tissue homogenate; 3. Properties of cell organelles
Factors affecting organelle density and size4. Centrifugal methods for the separation of organelles; Separation by size; Separation by density; Density perturbation; 5. Non-centrifugal procedures; Immunoisolation; Separation by electrophoresis; 6. Identification of separated material; Marker enzymes; Introduced markers for endocytic and exocytic pathways; Characteristic non-enzymatic proteins; 7. Assessment of the purity of fractions; Purity and purification; Problems from cell heterogeneity within tissues; Problems arising from organelle fragmentation Missorting in the exocytic and endocytic pathways8. Fractionation problems; No separation; Aggregation following resuspension of a fraction; Poor recovery of markers; Damage to cell structures; 9. A systematic approach to cell fractionation; Preliminary studies; Determination of the properties of components of the homogenate; Method development; Simplification of the separation; References; 3. Isolation and characterization of nuclei and nuclear subfractions; 1. Introduction; 2. Methods of preparing purified nuclei; Types of cells and tissue samples; Homogenization media Homogenization methodsCentrifugation conditions; Assays of nuclear purity; 3. Methods for purifying metaphase chromosomes; 4. Isolation of nuclear subfractions; Preparation of nucleoli; Preparation of nuclear membranes; Isolation of nuclear matrix; Preparation of nucleoids; 5. Isolation of nucleoprotein complexes; Isolation of polynucleosomes of chromatin; Ribonucleoproteins; 6. Isolation of nuclear macromolecules; Isolation of nuclear proteins; Isolation of nuclear RNA; Isolation of DNA; 7. Functional assays of nuclei; Analysis of DNA-binding proteins; Transcription assays; References 4. Subcellular fractionation of mitochondria1. Introduction; 2. Purification of mitochondria from various eukaryotic sources; Introduction; Protocols for purification of mitochondria from several eukaryotic sources; Further purification of mitochondrial fractions; 3. Determination of mitochondrial purity; Introduction; Use of the oxygen electrode to determine mitochondrial integrity; Determination of the integrity of the mitochondrial outer membrane; Glucose hexokinase trap method for estimation of P:O ratios; 4. Subfractionation of mitochondria Preparation of submitochondrial particles by sonication |
| Record Nr. | UNINA-9910455468303321 |
| Oxford ; ; New York, : IRL Press at Oxford University Press, c1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Subcellular fractionation [[electronic resource] ] : a practical approach / / edited by J.M. Graham and D. Rickwood
| Subcellular fractionation [[electronic resource] ] : a practical approach / / edited by J.M. Graham and D. Rickwood |
| Pubbl/distr/stampa | Oxford ; ; New York, : IRL Press at Oxford University Press, c1997 |
| Descrizione fisica | 1 online resource (360 p.) |
| Disciplina | 571.6/5 |
| Altri autori (Persone) |
GrahamJ. M <1943-> (John M.)
RickwoodD (David) |
| Collana | The practical approach series |
| Soggetto topico | Subcellular fractionation |
| ISBN |
1-283-66474-7
0-19-159161-0 0-585-48392-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; List of contributors; Abbreviations; 1. Homogenization of tissues and cells; 1. Introduction; 2. Aims of the homogenization procedure; 3. Influence of sample type; 4. Homogenization media; 5. Methods of homogenization; Type 1 homogenizers; Type 2 homogenizers; 6. Homogenization of tissues and cells; Mammalian liver; Brain; Muscle; Mammalian tissue culture cells; Plant organelles; Yeast; Other fungi and algae; Trypanosomes; Bacteria; References; 2. Isolation of subcellular fractions; 1. Introduction; 2. Composition of a tissue homogenate; 3. Properties of cell organelles
Factors affecting organelle density and size4. Centrifugal methods for the separation of organelles; Separation by size; Separation by density; Density perturbation; 5. Non-centrifugal procedures; Immunoisolation; Separation by electrophoresis; 6. Identification of separated material; Marker enzymes; Introduced markers for endocytic and exocytic pathways; Characteristic non-enzymatic proteins; 7. Assessment of the purity of fractions; Purity and purification; Problems from cell heterogeneity within tissues; Problems arising from organelle fragmentation Missorting in the exocytic and endocytic pathways8. Fractionation problems; No separation; Aggregation following resuspension of a fraction; Poor recovery of markers; Damage to cell structures; 9. A systematic approach to cell fractionation; Preliminary studies; Determination of the properties of components of the homogenate; Method development; Simplification of the separation; References; 3. Isolation and characterization of nuclei and nuclear subfractions; 1. Introduction; 2. Methods of preparing purified nuclei; Types of cells and tissue samples; Homogenization media Homogenization methodsCentrifugation conditions; Assays of nuclear purity; 3. Methods for purifying metaphase chromosomes; 4. Isolation of nuclear subfractions; Preparation of nucleoli; Preparation of nuclear membranes; Isolation of nuclear matrix; Preparation of nucleoids; 5. Isolation of nucleoprotein complexes; Isolation of polynucleosomes of chromatin; Ribonucleoproteins; 6. Isolation of nuclear macromolecules; Isolation of nuclear proteins; Isolation of nuclear RNA; Isolation of DNA; 7. Functional assays of nuclei; Analysis of DNA-binding proteins; Transcription assays; References 4. Subcellular fractionation of mitochondria1. Introduction; 2. Purification of mitochondria from various eukaryotic sources; Introduction; Protocols for purification of mitochondria from several eukaryotic sources; Further purification of mitochondrial fractions; 3. Determination of mitochondrial purity; Introduction; Use of the oxygen electrode to determine mitochondrial integrity; Determination of the integrity of the mitochondrial outer membrane; Glucose hexokinase trap method for estimation of P:O ratios; 4. Subfractionation of mitochondria Preparation of submitochondrial particles by sonication |
| Record Nr. | UNINA-9910780114603321 |
| Oxford ; ; New York, : IRL Press at Oxford University Press, c1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Subcellular fractionation : a practical approach / / edited by J.M. Graham and D. Rickwood
| Subcellular fractionation : a practical approach / / edited by J.M. Graham and D. Rickwood |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Oxford ; ; New York, : IRL Press at Oxford University Press, c1997 |
| Descrizione fisica | 1 online resource (360 p.) |
| Disciplina | 571.6/5 |
| Altri autori (Persone) |
GrahamJ. M <1943-> (John M.)
RickwoodD (David) |
| Collana | The practical approach series |
| Soggetto topico | Subcellular fractionation |
| ISBN |
1-283-66474-7
0-19-159161-0 0-585-48392-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; List of contributors; Abbreviations; 1. Homogenization of tissues and cells; 1. Introduction; 2. Aims of the homogenization procedure; 3. Influence of sample type; 4. Homogenization media; 5. Methods of homogenization; Type 1 homogenizers; Type 2 homogenizers; 6. Homogenization of tissues and cells; Mammalian liver; Brain; Muscle; Mammalian tissue culture cells; Plant organelles; Yeast; Other fungi and algae; Trypanosomes; Bacteria; References; 2. Isolation of subcellular fractions; 1. Introduction; 2. Composition of a tissue homogenate; 3. Properties of cell organelles
Factors affecting organelle density and size4. Centrifugal methods for the separation of organelles; Separation by size; Separation by density; Density perturbation; 5. Non-centrifugal procedures; Immunoisolation; Separation by electrophoresis; 6. Identification of separated material; Marker enzymes; Introduced markers for endocytic and exocytic pathways; Characteristic non-enzymatic proteins; 7. Assessment of the purity of fractions; Purity and purification; Problems from cell heterogeneity within tissues; Problems arising from organelle fragmentation Missorting in the exocytic and endocytic pathways8. Fractionation problems; No separation; Aggregation following resuspension of a fraction; Poor recovery of markers; Damage to cell structures; 9. A systematic approach to cell fractionation; Preliminary studies; Determination of the properties of components of the homogenate; Method development; Simplification of the separation; References; 3. Isolation and characterization of nuclei and nuclear subfractions; 1. Introduction; 2. Methods of preparing purified nuclei; Types of cells and tissue samples; Homogenization media Homogenization methodsCentrifugation conditions; Assays of nuclear purity; 3. Methods for purifying metaphase chromosomes; 4. Isolation of nuclear subfractions; Preparation of nucleoli; Preparation of nuclear membranes; Isolation of nuclear matrix; Preparation of nucleoids; 5. Isolation of nucleoprotein complexes; Isolation of polynucleosomes of chromatin; Ribonucleoproteins; 6. Isolation of nuclear macromolecules; Isolation of nuclear proteins; Isolation of nuclear RNA; Isolation of DNA; 7. Functional assays of nuclei; Analysis of DNA-binding proteins; Transcription assays; References 4. Subcellular fractionation of mitochondria1. Introduction; 2. Purification of mitochondria from various eukaryotic sources; Introduction; Protocols for purification of mitochondria from several eukaryotic sources; Further purification of mitochondrial fractions; 3. Determination of mitochondrial purity; Introduction; Use of the oxygen electrode to determine mitochondrial integrity; Determination of the integrity of the mitochondrial outer membrane; Glucose hexokinase trap method for estimation of P:O ratios; 4. Subfractionation of mitochondria Preparation of submitochondrial particles by sonication |
| Record Nr. | UNINA-9910823342303321 |
| Oxford ; ; New York, : IRL Press at Oxford University Press, c1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||