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Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis. Vol. 2
| Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis. Vol. 2 |
| Autore | Hughes Andrew B |
| Pubbl/distr/stampa | [Place of publication not identified], : Wiley VCH Imprint, 2009 |
| Descrizione fisica | 1 online resource (xxii, 683 pages) : illustrations |
| Disciplina | 547.750459 |
| Altri autori (Persone) | HughesAndrew B |
| Soggetto topico |
Amino acids - Synthesis
Amino acids Peptides Proteins |
| ISBN | 3-527-63178-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Synthesis and Chemistry of Modified Amino Acids. Synthesis and Chemistry of [alpha], [beta]- Didehydroamino Acids / Uli Kazmaier -- Synthesis and Chemistry of [alpha]-Hydrazino Acids / Jo︠lle Vidal -- Hydroxamic Acids: Chemistry, Bioactivity, and Solutionand Solid-Phase Synthesis / Darren Griffith, Marc Devocelle, Celine J Marmion -- Chemistry of a-Aminoboronic Acids and their Derivatives / Valery M Dembitsky, Morris Srebnik -- Chemistry of Aminophosphonic Acids and Phosphonopeptides / Valery P Kukhar, Vadim D Romanenko -- Chemistry of Silicon-Containing Amino Acids / Yingmei Qi, Scott Mcn Sieburth -- Amino Acid Organocatalysis. Catalysis of Reactions by Amino Acids / Haibo Xie, Thomas Hayes, Nicholas Gathergood -- Enzymes. Proteases as Powerful Catalysts for Organic Synthesis / Andres Illanes, Fanny Guzman, Sonia Barberis -- Semisynthetic Enzymes / Usama M Hegazy, Bengt Mannervik -- Catalysis by Peptide-Based Enzyme Models / Giovanna Ghirlanda, Leonard J Prins, Paolo Scrimin -- Substrate Recognition / Keith Brocklehurst, Sheraz Gul, Richard W Pickersgill -- Protein Recognition / Robyn E Mansfield, Arwen J Cross, Jacqueline M Matthews, Joel P Mackay -- Mammalian Peptide Hormones: Biosynthesis and Inhibition / Karen Brand, Annette G Beck-sickinger -- Insect Peptide Hormones / R Elwyn Isaac, Neil Audsley -- Plant Peptide Signals / Javier Narvaez-vasquez, Martha L Orozco-c̀rdenas, Gregory Pearce -- Nonribosomal Peptide Synthesis / Sean Doyle. |
| Record Nr. | UNINA-9910830732903321 |
Hughes Andrew B
|
||
| [Place of publication not identified], : Wiley VCH Imprint, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis. Vol. 2
| Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis. Vol. 2 |
| Autore | Hughes Andrew B |
| Pubbl/distr/stampa | [Place of publication not identified], : Wiley VCH Imprint, 2009 |
| Descrizione fisica | 1 online resource (xxii, 683 pages) : illustrations |
| Disciplina | 547.750459 |
| Altri autori (Persone) | HughesAndrew B |
| Soggetto topico |
Amino acids - Synthesis
Amino acids Peptides Proteins |
| ISBN | 3-527-63178-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Synthesis and Chemistry of Modified Amino Acids. Synthesis and Chemistry of [alpha], [beta]- Didehydroamino Acids / Uli Kazmaier -- Synthesis and Chemistry of [alpha]-Hydrazino Acids / Jo︠lle Vidal -- Hydroxamic Acids: Chemistry, Bioactivity, and Solutionand Solid-Phase Synthesis / Darren Griffith, Marc Devocelle, Celine J Marmion -- Chemistry of a-Aminoboronic Acids and their Derivatives / Valery M Dembitsky, Morris Srebnik -- Chemistry of Aminophosphonic Acids and Phosphonopeptides / Valery P Kukhar, Vadim D Romanenko -- Chemistry of Silicon-Containing Amino Acids / Yingmei Qi, Scott Mcn Sieburth -- Amino Acid Organocatalysis. Catalysis of Reactions by Amino Acids / Haibo Xie, Thomas Hayes, Nicholas Gathergood -- Enzymes. Proteases as Powerful Catalysts for Organic Synthesis / Andres Illanes, Fanny Guzman, Sonia Barberis -- Semisynthetic Enzymes / Usama M Hegazy, Bengt Mannervik -- Catalysis by Peptide-Based Enzyme Models / Giovanna Ghirlanda, Leonard J Prins, Paolo Scrimin -- Substrate Recognition / Keith Brocklehurst, Sheraz Gul, Richard W Pickersgill -- Protein Recognition / Robyn E Mansfield, Arwen J Cross, Jacqueline M Matthews, Joel P Mackay -- Mammalian Peptide Hormones: Biosynthesis and Inhibition / Karen Brand, Annette G Beck-sickinger -- Insect Peptide Hormones / R Elwyn Isaac, Neil Audsley -- Plant Peptide Signals / Javier Narvaez-vasquez, Martha L Orozco-c̀rdenas, Gregory Pearce -- Nonribosomal Peptide Synthesis / Sean Doyle. |
| Record Nr. | UNINA-9910841041703321 |
|
Hughes Andrew B
|
||
| [Place of publication not identified], : Wiley VCH Imprint, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Asymmetric synthesis of non-proteinogenic amino acids / / Ashot S. Saghyan and Peter Langer
| Asymmetric synthesis of non-proteinogenic amino acids / / Ashot S. Saghyan and Peter Langer |
| Autore | Saghyan Ashot S. |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2016 |
| Descrizione fisica | 1 online resource (376 p.) |
| Disciplina | 547.750459 |
| Soggetto topico | Amino acids - Synthesis |
| ISBN |
3-527-80448-X
3-527-80447-1 3-527-80449-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover ; Title Page ; Copyright ; Contents ; List of Abbreviations ; Introduction ; Chapter 1 Non-Proteinogenic -Amino Acids, Natural Origin, Biological Functions; References ; Part I Natural Synthesis of Amino Acids, Mechanisms, and Modeling; References ; Chapter 2 Some Regularities of Mechanisms for the Natural Synthesis of Amino Acids ; References
Chapter 3 Systems for Modeling Some Aspects of Pyridoxal Enzyme Action References ; Chapter 4 Modeling of Processes Associated with Cleavage of C -H and C -C Bonds; References ; Chapter 5 Modeling of , -Elimination Processes of PP-Catalysis, Kinetics, and Stereochemistry; References Chapter 6 Biomimetic Addition Reaction of Nucleophiles to CoIII Complexes of Dehydroaminobutyric Acid References ; Part II Asymmetric Synthesis of Nonprotein -Amino Acids; Chapter 7 The Main Rules of Asymmetric Synthesis ; References ; Chapter 8 Catalytic Asymmetric Synthesis 8.1 Achiral NiII Complexes of Schiff Bases of Amino Acids 8.1.1 The Alkylation of Achiral NiII Complexes Under Phase-Transfer Catalysis ; 8.1.2 Reactions of 1,4-Michael Addition to Achiral Glycine and Dehydroalanine Complexes ; 8.1.3 Synthesis of Enantiomerically Enriched -Amino Acids 8.1.3.1 The Asymmetric Alkylation of Substrate 65a by Alkyl Halides Under Phase-Transfer Catalysis 8.1.3.2 Asymmetric Aldol Condensation of Achiral NiII Complexes of Amino Acids ; 8.1.3.3 The Asymmetric Michael Addition of Achiral NiII Substrates to Electron-Withdrawing Compounds 8.1.3.4 Catalytic Asymmetric Addition of Nucleophiles to an Achiral Dehydroalanine Substrate |
| Record Nr. | UNINA-9910134851503321 |
|
Saghyan Ashot S.
|
||
| Weinheim, Germany : , : Wiley-VCH, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Asymmetric synthesis of non-proteinogenic amino acids / / Ashot S. Saghyan and Peter Langer
| Asymmetric synthesis of non-proteinogenic amino acids / / Ashot S. Saghyan and Peter Langer |
| Autore | Saghyan Ashot S. |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2016 |
| Descrizione fisica | 1 online resource (376 p.) |
| Disciplina | 547.750459 |
| Soggetto topico | Amino acids - Synthesis |
| ISBN |
3-527-80448-X
3-527-80447-1 3-527-80449-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover ; Title Page ; Copyright ; Contents ; List of Abbreviations ; Introduction ; Chapter 1 Non-Proteinogenic -Amino Acids, Natural Origin, Biological Functions; References ; Part I Natural Synthesis of Amino Acids, Mechanisms, and Modeling; References ; Chapter 2 Some Regularities of Mechanisms for the Natural Synthesis of Amino Acids ; References
Chapter 3 Systems for Modeling Some Aspects of Pyridoxal Enzyme Action References ; Chapter 4 Modeling of Processes Associated with Cleavage of C -H and C -C Bonds; References ; Chapter 5 Modeling of , -Elimination Processes of PP-Catalysis, Kinetics, and Stereochemistry; References Chapter 6 Biomimetic Addition Reaction of Nucleophiles to CoIII Complexes of Dehydroaminobutyric Acid References ; Part II Asymmetric Synthesis of Nonprotein -Amino Acids; Chapter 7 The Main Rules of Asymmetric Synthesis ; References ; Chapter 8 Catalytic Asymmetric Synthesis 8.1 Achiral NiII Complexes of Schiff Bases of Amino Acids 8.1.1 The Alkylation of Achiral NiII Complexes Under Phase-Transfer Catalysis ; 8.1.2 Reactions of 1,4-Michael Addition to Achiral Glycine and Dehydroalanine Complexes ; 8.1.3 Synthesis of Enantiomerically Enriched -Amino Acids 8.1.3.1 The Asymmetric Alkylation of Substrate 65a by Alkyl Halides Under Phase-Transfer Catalysis 8.1.3.2 Asymmetric Aldol Condensation of Achiral NiII Complexes of Amino Acids ; 8.1.3.3 The Asymmetric Michael Addition of Achiral NiII Substrates to Electron-Withdrawing Compounds 8.1.3.4 Catalytic Asymmetric Addition of Nucleophiles to an Achiral Dehydroalanine Substrate |
| Record Nr. | UNINA-9910821460103321 |
|
Saghyan Ashot S.
|
||
| Weinheim, Germany : , : Wiley-VCH, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Origins and Synthesis of Amino Acids. Vol. 1
| Origins and Synthesis of Amino Acids. Vol. 1 |
| Autore | Hughes William |
| Pubbl/distr/stampa | [Place of publication not identified], : Wiley VCH Imprint, 2009 |
| Descrizione fisica | 1 online resource (xix, 701 pages) |
| Disciplina | 547.750459 |
| Soggetto topico |
Amino acids - Synthesis
Amino acids Peptides Proteins |
| ISBN | 3-527-63176-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | List of Contributors XV 1 Mass Spectrometry of Amino Acids and Proteins 1 Simin D. Maleknia and Richard Johnson 1.1 Introduction 1 1.2 Basic Protein Chemistry and How it Relates to MS 21 1.3 Sample Preparation and Data Acquisition 28 1.4 Data Analysis of LC-MS/MS (or CE-MS/MS) of Mixtures 32 1.5 MS of Protein Structure, Folding, and Interactions 36 1.6 Conclusions and Perspectives 40 References 40 2 X-Ray Structure Determination of Proteins and Peptides 51 Andrew J. Fisher 2.1 Introduction 51 2.2 Growing Crystals 55 2.3 Symmetry and Space Groups 62 2.4 X-Ray Scattering and Diffraction 67 2.5 Collecting and Processing Diffraction Data 82 2.6 Solving the Structure (Determining Phases) 83 2.7 Analyzing and Refining the Structure 90 References 94 3 Nuclear Magnetic Resonance of Amino Acids, Peptides, and Proteins 97 Andrea Bernini and Pierandrea Temussi 3.1 Introduction 97 3.2 Amino Acids 101 3.3 Peptides 113 3.4 Proteins 129 3.5 Conclusions 145 References 146 4 Structure and Activity of N-Methylated Peptides 155 Raymond S. Norton 4.1 Introduction 155 4.2 Conformational Effects of N-Methylation 157 4.3 Effects of N-Methylation on Bioactive Peptides 159 4.4 Concluding Remarks 162 References 163 5 High-Performance Liquid Chromatography of Peptides and Proteins 167 Reinhard I. Boysen and Milton T.W. Hearn 5.1 Introduction 167 5.2 Basic Terms and Concepts in Chromatography 169 5.3 Chemical Structure of Peptides and Proteins 173 5.4 HPLC Separation Modes in Peptide and Protein Analysis 177 5.5 Method Development from Analytical to Preparative Scale Illustrated for HP-RPC 189 5.6 Multidimensional HPLC 198 5.7 Conclusions 206 References 207 6 Local Surface Plasmon Resonance and Electrochemical Biosensing Systems for Analyzing Functional Peptides 211 Masato Saito and Eiichi Tamiya 6.1 Localized Surface Plasmon Resonance (LSPR)-Based Microfluidics Biosensor for the Detection of Insulin Peptide Hormone 211 6.2 Electrochemical LSPR-Based Label-Free Detection of Melittin 215 6.3 Label-Free Electrochemical Monitoring of b-Amyloid (Ab) Peptide Aggregation 218 References 221 7 Surface Plasmon Resonance Spectroscopy in the Biosciences 225 Jing Yuan, Yinqiu Wu, and Marie-Isabel Aguilar 7.1 Introduction 225 7.2 SPR-Based Optical Biosensors 225 7.3 Principle of Operation of SPR Biosensors 226 7.4 Description of a SPR Instrument 228 7.5 Application of SPR in Immunosensor Design 230 7.6 Application of SPR in Membrane Interactions 234 7.7 Data Analysis 240 7.8 Conclusions 243 References 244 8 Atomic Force Microscopy of Proteins 249 Adam Mechler 8.1 Foreword 249 8.2 AFM 250 8.3 Bioimaging Highlights 253 8.4 Issues 261 8.5 Force Measurements 269 8.6 Liquid Imaging 269 8.7 Sample Preparation for Bioimaging 272 8.8 Outlook 274 References 275 9 Solvent Interactions with Proteins and Other Macromolecules 277 Satoshi Ohtake, Yoshiko Kita, Kouhei Tsumoto, and Tsutomu Arakawa 9.1 Introduction 277 9.2 Solvent Applications 280 9.3 Solvent Application for Viruses 300 9.4 Solvent Application for DNA 310 9.5 Mechanism 314 9.6 Protein-Solvent Interactions in Frozen and Freeze-Dried Systems 342 9.7 Conclusions 348 References 349 10 Role of Cysteine 361 Lalla A. Ba, Torsten Burkholz, Thomas Schneider, and Claus Jacob 10.1 Sulfur: A Redox Chameleon with Many Faces 361 10.2 Three Faces of Thiols: Nucleophilicity, Redox Activity, and Metal Binding 365 10.3 Towards a Dynamic Picture of Disulfide Bonds 371 10.4 Chemical Protection and Regulation via S-Thiolation 374 10.5 ''Dormant'' Catalytic Sites 378 10.6 Peroxiredoxin/Sulfiredoxin Catalysis and Control Pathway 379 10.7 Higher Sulfur Oxidation States: From the Shadows to the Heart of Biological Sulfur Chemistry 384 10.8 Cysteine as a Target for Oxidants, Metal Ions, and Drug Molecules 388 10.9 Conclusions and Outlook 390 References 391 11 Role of Disulfide Bonds in Peptide and Protein Conformation 395 Keith K. Khoo and Raymond S. Norton 11.1 Introduction 395 11.2 Probing the Role of Disulfide Bonds 396 11.3 Contribution of Disulfide Bonds to Protein Stability 396 11.4 Role of Disulfide Bonds in Protein Folding 397 11.5 Role of Individual Disulfide Bonds in Protein Structure 399 11.6 Disulfide Bonds in Protein Dynamics 401 11.7 Disulfide Bonding Patterns and Protein Topology 403 11.8 Applications 408 11.9 Conclusions 409 References 410 12 Quantitative Mass Spectrometry-Based Proteomics 419 Shao-En Ong 12.1 Introduction 419 12.2 Quantification in Biological MS 420 12.3 Identifying Proteins Interacting with Small Molecules with Quantitative Proteomics 430 12.4 Conclusions 433 References 434 13 Two-Dimensional Gel Electrophoresis and Protein/Polypeptide Assignment 439 Takashi Manabe and Ya Jin 13.1 Introduction 439 13.2 Aim of Protein Analysis and Development of 2-DE Techniques 439 13.3 Current Status of 2-DE Techniques 441 13.4 Development of Protein Assignment Techniques on 2-DE Gels and Current Status of Mass Spectrometric Techniques 452 13.5 Conclusions 460 References 460 14 Bioinformatics Tools for Detecting Post-Translational Modifications in Mass Spectrometry Data 463 Patricia M. Palagi, Erik Arhné, MarKus Müller, and Frédérique Lisacek 14.1 Introduction 463 14.2 PTM Discovery with MS 465 14.3 Database Resources for PTM Analysis 470 14.4 Conclusions 473 References 473 Index 477. |
| Record Nr. | UNINA-9910830308003321 |
|
Hughes William
|
||
| [Place of publication not identified], : Wiley VCH Imprint, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Origins and Synthesis of Amino Acids. Vol. 1
| Origins and Synthesis of Amino Acids. Vol. 1 |
| Autore | Hughes William |
| Pubbl/distr/stampa | [Place of publication not identified], : Wiley VCH Imprint, 2009 |
| Descrizione fisica | 1 online resource (xix, 701 pages) |
| Disciplina | 547.750459 |
| Soggetto topico |
Amino acids - Synthesis
Amino acids Peptides Proteins |
| ISBN | 3-527-63176-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | List of Contributors XV 1 Mass Spectrometry of Amino Acids and Proteins 1 Simin D. Maleknia and Richard Johnson 1.1 Introduction 1 1.2 Basic Protein Chemistry and How it Relates to MS 21 1.3 Sample Preparation and Data Acquisition 28 1.4 Data Analysis of LC-MS/MS (or CE-MS/MS) of Mixtures 32 1.5 MS of Protein Structure, Folding, and Interactions 36 1.6 Conclusions and Perspectives 40 References 40 2 X-Ray Structure Determination of Proteins and Peptides 51 Andrew J. Fisher 2.1 Introduction 51 2.2 Growing Crystals 55 2.3 Symmetry and Space Groups 62 2.4 X-Ray Scattering and Diffraction 67 2.5 Collecting and Processing Diffraction Data 82 2.6 Solving the Structure (Determining Phases) 83 2.7 Analyzing and Refining the Structure 90 References 94 3 Nuclear Magnetic Resonance of Amino Acids, Peptides, and Proteins 97 Andrea Bernini and Pierandrea Temussi 3.1 Introduction 97 3.2 Amino Acids 101 3.3 Peptides 113 3.4 Proteins 129 3.5 Conclusions 145 References 146 4 Structure and Activity of N-Methylated Peptides 155 Raymond S. Norton 4.1 Introduction 155 4.2 Conformational Effects of N-Methylation 157 4.3 Effects of N-Methylation on Bioactive Peptides 159 4.4 Concluding Remarks 162 References 163 5 High-Performance Liquid Chromatography of Peptides and Proteins 167 Reinhard I. Boysen and Milton T.W. Hearn 5.1 Introduction 167 5.2 Basic Terms and Concepts in Chromatography 169 5.3 Chemical Structure of Peptides and Proteins 173 5.4 HPLC Separation Modes in Peptide and Protein Analysis 177 5.5 Method Development from Analytical to Preparative Scale Illustrated for HP-RPC 189 5.6 Multidimensional HPLC 198 5.7 Conclusions 206 References 207 6 Local Surface Plasmon Resonance and Electrochemical Biosensing Systems for Analyzing Functional Peptides 211 Masato Saito and Eiichi Tamiya 6.1 Localized Surface Plasmon Resonance (LSPR)-Based Microfluidics Biosensor for the Detection of Insulin Peptide Hormone 211 6.2 Electrochemical LSPR-Based Label-Free Detection of Melittin 215 6.3 Label-Free Electrochemical Monitoring of b-Amyloid (Ab) Peptide Aggregation 218 References 221 7 Surface Plasmon Resonance Spectroscopy in the Biosciences 225 Jing Yuan, Yinqiu Wu, and Marie-Isabel Aguilar 7.1 Introduction 225 7.2 SPR-Based Optical Biosensors 225 7.3 Principle of Operation of SPR Biosensors 226 7.4 Description of a SPR Instrument 228 7.5 Application of SPR in Immunosensor Design 230 7.6 Application of SPR in Membrane Interactions 234 7.7 Data Analysis 240 7.8 Conclusions 243 References 244 8 Atomic Force Microscopy of Proteins 249 Adam Mechler 8.1 Foreword 249 8.2 AFM 250 8.3 Bioimaging Highlights 253 8.4 Issues 261 8.5 Force Measurements 269 8.6 Liquid Imaging 269 8.7 Sample Preparation for Bioimaging 272 8.8 Outlook 274 References 275 9 Solvent Interactions with Proteins and Other Macromolecules 277 Satoshi Ohtake, Yoshiko Kita, Kouhei Tsumoto, and Tsutomu Arakawa 9.1 Introduction 277 9.2 Solvent Applications 280 9.3 Solvent Application for Viruses 300 9.4 Solvent Application for DNA 310 9.5 Mechanism 314 9.6 Protein-Solvent Interactions in Frozen and Freeze-Dried Systems 342 9.7 Conclusions 348 References 349 10 Role of Cysteine 361 Lalla A. Ba, Torsten Burkholz, Thomas Schneider, and Claus Jacob 10.1 Sulfur: A Redox Chameleon with Many Faces 361 10.2 Three Faces of Thiols: Nucleophilicity, Redox Activity, and Metal Binding 365 10.3 Towards a Dynamic Picture of Disulfide Bonds 371 10.4 Chemical Protection and Regulation via S-Thiolation 374 10.5 ''Dormant'' Catalytic Sites 378 10.6 Peroxiredoxin/Sulfiredoxin Catalysis and Control Pathway 379 10.7 Higher Sulfur Oxidation States: From the Shadows to the Heart of Biological Sulfur Chemistry 384 10.8 Cysteine as a Target for Oxidants, Metal Ions, and Drug Molecules 388 10.9 Conclusions and Outlook 390 References 391 11 Role of Disulfide Bonds in Peptide and Protein Conformation 395 Keith K. Khoo and Raymond S. Norton 11.1 Introduction 395 11.2 Probing the Role of Disulfide Bonds 396 11.3 Contribution of Disulfide Bonds to Protein Stability 396 11.4 Role of Disulfide Bonds in Protein Folding 397 11.5 Role of Individual Disulfide Bonds in Protein Structure 399 11.6 Disulfide Bonds in Protein Dynamics 401 11.7 Disulfide Bonding Patterns and Protein Topology 403 11.8 Applications 408 11.9 Conclusions 409 References 410 12 Quantitative Mass Spectrometry-Based Proteomics 419 Shao-En Ong 12.1 Introduction 419 12.2 Quantification in Biological MS 420 12.3 Identifying Proteins Interacting with Small Molecules with Quantitative Proteomics 430 12.4 Conclusions 433 References 434 13 Two-Dimensional Gel Electrophoresis and Protein/Polypeptide Assignment 439 Takashi Manabe and Ya Jin 13.1 Introduction 439 13.2 Aim of Protein Analysis and Development of 2-DE Techniques 439 13.3 Current Status of 2-DE Techniques 441 13.4 Development of Protein Assignment Techniques on 2-DE Gels and Current Status of Mass Spectrometric Techniques 452 13.5 Conclusions 460 References 460 14 Bioinformatics Tools for Detecting Post-Translational Modifications in Mass Spectrometry Data 463 Patricia M. Palagi, Erik Arhné, MarKus Müller, and Frédérique Lisacek 14.1 Introduction 463 14.2 PTM Discovery with MS 465 14.3 Database Resources for PTM Analysis 470 14.4 Conclusions 473 References 473 Index 477. |
| Record Nr. | UNINA-9910840789903321 |
|
Hughes William
|
||
| [Place of publication not identified], : Wiley VCH Imprint, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Synthese und anwendung eines neuen spinlabels und Untersuchung der assoziation von nukleobasen-funktionalisierten transmembranpeptiden in lipiddoppelschichten / / Sven Stoller
| Synthese und anwendung eines neuen spinlabels und Untersuchung der assoziation von nukleobasen-funktionalisierten transmembranpeptiden in lipiddoppelschichten / / Sven Stoller |
| Autore | Stoller Sven |
| Pubbl/distr/stampa | Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 |
| Descrizione fisica | 1 online resource (150 pages) : illustrations |
| Disciplina | 547.750459 |
| Soggetto topico | Amino acids - Derivatives - Synthesis |
| ISBN | 3-7369-3752-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910794956403321 |
|
Stoller Sven
|
||
| Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Synthese und anwendung eines neuen spinlabels und Untersuchung der assoziation von nukleobasen-funktionalisierten transmembranpeptiden in lipiddoppelschichten / / Sven Stoller
| Synthese und anwendung eines neuen spinlabels und Untersuchung der assoziation von nukleobasen-funktionalisierten transmembranpeptiden in lipiddoppelschichten / / Sven Stoller |
| Autore | Stoller Sven |
| Pubbl/distr/stampa | Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 |
| Descrizione fisica | 1 online resource (150 pages) : illustrations |
| Disciplina | 547.750459 |
| Soggetto topico | Amino acids - Derivatives - Synthesis |
| ISBN | 3-7369-3752-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910814288903321 |
|
Stoller Sven
|
||
| Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||