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MALDI MS : a practical guide to instrumentation, methods and applications / / edited by Franz Hillenkamp and Jasna Peter-Katalinic
| MALDI MS : a practical guide to instrumentation, methods and applications / / edited by Franz Hillenkamp and Jasna Peter-Katalinic |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Weinheim : , : Wiley Blackwell, , [2014] |
| Descrizione fisica | 1 online resource (477 p.) |
| Disciplina | 547.70154365 |
| Altri autori (Persone) |
HillenkampF
Peter-KatalinićJasna |
| Soggetto topico | Matrix-assisted laser desorption-ionization |
| Soggetto genere / forma | Electronic books. |
| ISBN |
3-527-67374-1
3-527-33596-X 3-527-67373-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Related Titles; Title page; Copyright page; Contents; Preface to the Second Edition; List of Contributors; 1: The MALDI Process and Method; 1.1 Introduction; 1.2 Analyte Incorporation; 1.3 Absorption of the Laser Radiation; 1.4 The Ablation/Desorption Process; 1.5 Ionization; 1.6 Fragmentation of MALDI Ions; 1.7 MALDI of Noncovalent Complexes; 1.8 The Optimal Choice of Matrix: Sample Preparation; 1.8.1 Surface Preparation; 1.8.2 Anchor Sample Plates; 1.8.3 Matrix Additives and Influence of the Sample Plate Surface; Abbreviations; References; 2: MALDI Mass Spectrometry Instrumentation
2.1 Introduction2.2 Lasers for MALDI-MS; 2.3 Fragmentation of MALDI Ions; 2.3.1 MALDI at Elevated Pressure; 2.3.2 Tandem Mass Spectrometry of MALDI Ions; 2.4 Mass Analyzers; 2.4.1 Axial TOF Mass Spectrometers; 2.4.2 Reflectron TOF Mass Spectrometers; 2.4.3 Tandem TOF Mass Spectrometers; 2.4.4 Orthogonal TOF Mass Analyzers; 2.4.5 Tandem Mass Spectrometry in oTOF Mass Analyzers; 2.4.6 Ion Detectors and Data Processing in MALDI-TOF Analyzers; 2.5 Fourier Transform Ion Cyclotron Resonance Mass Spectrometers; 2.5.1 Tandem Mass Spectrometry on FTICR Mass Spectrometers 2.6 Quadrupole Ion Trap Mass Spectrometers2.6.1 RF-Only Ion Guides and LIT Mass Spectrometers; 2.6.2 Tandem Mass Spectrometry on QIT Mass Spectrometers; 2.7 Hybrid Mass Spectrometers; 2.7.1 Quadrupole TOF Mass Spectrometers; 2.7.2 Quadrupole FT Mass Spectrometers; 2.7.3 QIT-TOF Mass Spectrometers; 2.7.4 Ion Mobility oTOF Mass Spectrometers; 2.7.5 Orbitrap; 2.8 Future Directions; Definitions and Acronyms; References; 3: MALDI-MS in Protein Chemistry and Proteomics; 3.1 Introduction; 3.2 Sample Preparation for Protein and Peptide Analysis by MALDI-MS 3.3 Strategies for Using MALDI-MS in Protein Biochemistry3.3.1 Peptide Mass Mapping of Purified Proteins; 3.3.2 Peptide Sequencing by MALDI-MS/MS; 3.3.3 Analysis of Post-Translational Modifications; 3.4 Applications of MALDI-MS in Proteomics; 3.4.1 Protein Identification by MALDI-MS Peptide Mass Mapping; 3.4.2 Quantitation of Proteins by MALDI-MS; 3.5 Computational Tools for Protein Analysis by MALDI-MS; 3.6 Clinical Applications of MALDI-MS; 3.7 Conclusions; Acknowledgments; References; 4: MALDI-Mass Spectrometry Imaging; 4.1 Introduction 4.2 History of Mass Spectrometry Imaging (MSI) and Microprobing Techniques4.3 MALDI in Micro Dimensions: Instruments and Mechanistic Differences; 4.4 Visualization of Mass Spectrometric Information; 4.5 Data Processing and Data Exchange; 4.6 Matrix Deposition for High-Resolution Imaging; 4.7 Organisms, Organs, and Tissues: MALDI Imaging at Various Lateral Resolutions; 4.7.1 Phospholipid Analysis; 4.7.2 Peptide Analysis; 4.7.3 Drug Monitoring; 4.8 Whole-Cell and Single-Cell Analysis; 4.8.1 Cellular Analysis; 4.8.2 Individually Isolated Cells; 4.8.3 Direct Cellular and Subcellular Imaging 4.9 Cell Sorting and Capturing |
| Record Nr. | UNINA-9910139000003321 |
| Weinheim : , : Wiley Blackwell, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
MALDI MS : a practical guide to instrumentation, methods and applications / / edited by Franz Hillenkamp and Jasna Peter-Katalinic
| MALDI MS : a practical guide to instrumentation, methods and applications / / edited by Franz Hillenkamp and Jasna Peter-Katalinic |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Weinheim : , : Wiley Blackwell, , [2014] |
| Descrizione fisica | 1 online resource (477 p.) |
| Disciplina | 547.70154365 |
| Altri autori (Persone) |
HillenkampF
Peter-KatalinićJasna |
| Soggetto topico | Matrix-assisted laser desorption-ionization |
| ISBN |
3-527-67374-1
3-527-33596-X 3-527-67373-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Related Titles; Title page; Copyright page; Contents; Preface to the Second Edition; List of Contributors; 1: The MALDI Process and Method; 1.1 Introduction; 1.2 Analyte Incorporation; 1.3 Absorption of the Laser Radiation; 1.4 The Ablation/Desorption Process; 1.5 Ionization; 1.6 Fragmentation of MALDI Ions; 1.7 MALDI of Noncovalent Complexes; 1.8 The Optimal Choice of Matrix: Sample Preparation; 1.8.1 Surface Preparation; 1.8.2 Anchor Sample Plates; 1.8.3 Matrix Additives and Influence of the Sample Plate Surface; Abbreviations; References; 2: MALDI Mass Spectrometry Instrumentation
2.1 Introduction2.2 Lasers for MALDI-MS; 2.3 Fragmentation of MALDI Ions; 2.3.1 MALDI at Elevated Pressure; 2.3.2 Tandem Mass Spectrometry of MALDI Ions; 2.4 Mass Analyzers; 2.4.1 Axial TOF Mass Spectrometers; 2.4.2 Reflectron TOF Mass Spectrometers; 2.4.3 Tandem TOF Mass Spectrometers; 2.4.4 Orthogonal TOF Mass Analyzers; 2.4.5 Tandem Mass Spectrometry in oTOF Mass Analyzers; 2.4.6 Ion Detectors and Data Processing in MALDI-TOF Analyzers; 2.5 Fourier Transform Ion Cyclotron Resonance Mass Spectrometers; 2.5.1 Tandem Mass Spectrometry on FTICR Mass Spectrometers 2.6 Quadrupole Ion Trap Mass Spectrometers2.6.1 RF-Only Ion Guides and LIT Mass Spectrometers; 2.6.2 Tandem Mass Spectrometry on QIT Mass Spectrometers; 2.7 Hybrid Mass Spectrometers; 2.7.1 Quadrupole TOF Mass Spectrometers; 2.7.2 Quadrupole FT Mass Spectrometers; 2.7.3 QIT-TOF Mass Spectrometers; 2.7.4 Ion Mobility oTOF Mass Spectrometers; 2.7.5 Orbitrap; 2.8 Future Directions; Definitions and Acronyms; References; 3: MALDI-MS in Protein Chemistry and Proteomics; 3.1 Introduction; 3.2 Sample Preparation for Protein and Peptide Analysis by MALDI-MS 3.3 Strategies for Using MALDI-MS in Protein Biochemistry3.3.1 Peptide Mass Mapping of Purified Proteins; 3.3.2 Peptide Sequencing by MALDI-MS/MS; 3.3.3 Analysis of Post-Translational Modifications; 3.4 Applications of MALDI-MS in Proteomics; 3.4.1 Protein Identification by MALDI-MS Peptide Mass Mapping; 3.4.2 Quantitation of Proteins by MALDI-MS; 3.5 Computational Tools for Protein Analysis by MALDI-MS; 3.6 Clinical Applications of MALDI-MS; 3.7 Conclusions; Acknowledgments; References; 4: MALDI-Mass Spectrometry Imaging; 4.1 Introduction 4.2 History of Mass Spectrometry Imaging (MSI) and Microprobing Techniques4.3 MALDI in Micro Dimensions: Instruments and Mechanistic Differences; 4.4 Visualization of Mass Spectrometric Information; 4.5 Data Processing and Data Exchange; 4.6 Matrix Deposition for High-Resolution Imaging; 4.7 Organisms, Organs, and Tissues: MALDI Imaging at Various Lateral Resolutions; 4.7.1 Phospholipid Analysis; 4.7.2 Peptide Analysis; 4.7.3 Drug Monitoring; 4.8 Whole-Cell and Single-Cell Analysis; 4.8.1 Cellular Analysis; 4.8.2 Individually Isolated Cells; 4.8.3 Direct Cellular and Subcellular Imaging 4.9 Cell Sorting and Capturing |
| Record Nr. | UNINA-9910677262003321 |
| Weinheim : , : Wiley Blackwell, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||