Bioorganic and medicinal chemistry of fluorine [[electronic resource] /] / Jean-Pierre Bégué, Danièle Bonnet-Delpon ; translated from French by Julien Legros |
Autore | Bégué Jean-Pierre |
Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, c2008 |
Descrizione fisica | 1 online resource (385 p.) |
Disciplina |
547.02
547/.02 |
Altri autori (Persone) | Bonnet-DelponDanièle |
Soggetto topico |
Fluorine compounds - Therapeutic use
Fluorine - Physiological effect Organofluorine compounds Bioorganic chemistry |
Soggetto genere / forma | Electronic books. |
ISBN |
1-281-38145-4
9786611381455 0-470-28189-8 0-470-28187-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | General remarks on structural, physical, and chemical properties of fluorinated compounds -- Overview on the preparation of fluorinated compounds -- Effects of fluorine substitution on biological properties -- Fluorinated analogues of natural products -- Fluorinated derivatives of ?-amino acids and proteins -- Saccharidic fluorinated derivatives -- Inhibition of enzymes by fluorinated compounds -- Fluorinated drugs. |
Record Nr. | UNINA-9910143829203321 |
Bégué Jean-Pierre | ||
Hoboken, N.J., : John Wiley & Sons, c2008 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Bioorganic and medicinal chemistry of fluorine [[electronic resource] /] / Jean-Pierre Bégué, Danièle Bonnet-Delpon ; translated from French by Julien Legros |
Autore | Bégué Jean-Pierre |
Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, c2008 |
Descrizione fisica | 1 online resource (385 p.) |
Disciplina |
547.02
547/.02 |
Altri autori (Persone) | Bonnet-DelponDanièle |
Soggetto topico |
Fluorine compounds - Therapeutic use
Fluorine - Physiological effect Organofluorine compounds Bioorganic chemistry |
ISBN |
1-281-38145-4
9786611381455 0-470-28189-8 0-470-28187-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | General remarks on structural, physical, and chemical properties of fluorinated compounds -- Overview on the preparation of fluorinated compounds -- Effects of fluorine substitution on biological properties -- Fluorinated analogues of natural products -- Fluorinated derivatives of ?-amino acids and proteins -- Saccharidic fluorinated derivatives -- Inhibition of enzymes by fluorinated compounds -- Fluorinated drugs. |
Record Nr. | UNINA-9910830834403321 |
Bégué Jean-Pierre | ||
Hoboken, N.J., : John Wiley & Sons, c2008 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Fluorine in organic chemistry |
Autore | Chambers R. D |
Pubbl/distr/stampa | [Place of publication not identified], : Blackwell Pub, 2004 |
Disciplina | 547.02 |
Soggetto topico |
Organofluorine compounds
Fluorine Compounds Fluorine Inorganic Chemicals Halogens Chemicals and Drugs Elements Organic Chemistry Chemistry Physical Sciences & Mathematics |
ISBN |
1-4443-0537-9
1-4443-0555-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910139385803321 |
Chambers R. D | ||
[Place of publication not identified], : Blackwell Pub, 2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Fluorine in organic chemistry |
Autore | Chambers R. D |
Pubbl/distr/stampa | [Place of publication not identified], : Blackwell Pub, 2004 |
Disciplina | 547.02 |
Soggetto topico |
Organofluorine compounds
Fluorine Compounds Fluorine Inorganic Chemicals Halogens Chemicals and Drugs Elements Organic Chemistry Chemistry Physical Sciences & Mathematics |
ISBN |
1-4443-0537-9
1-4443-0555-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-996201607803316 |
Chambers R. D | ||
[Place of publication not identified], : Blackwell Pub, 2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. di Salerno | ||
|
Fluorine in organic chemistry |
Autore | Chambers R. D |
Pubbl/distr/stampa | [Place of publication not identified], : Blackwell Pub, 2004 |
Disciplina | 547.02 |
Soggetto topico |
Organofluorine compounds
Fluorine Compounds Fluorine Inorganic Chemicals Halogens Chemicals and Drugs Elements Organic Chemistry Chemistry Physical Sciences & Mathematics |
ISBN |
1-4443-0537-9
1-4443-0555-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910831062903321 |
Chambers R. D | ||
[Place of publication not identified], : Blackwell Pub, 2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook of fluorous chemistry [[electronic resource] /] / John A. Gladysz, Dennis P. Curran, István T. Horváth (Eds.) |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (627 p.) |
Disciplina |
546/.731
547.02 |
Altri autori (Persone) |
GladyszJohn A
CurranDennis P HorváthIstván T |
Soggetto topico |
Fluorine compounds
Fluorine |
ISBN |
1-280-51979-7
9786610519798 3-527-60390-5 3-527-60449-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Handbook of Fluorous Chemistry; Contents; Preface; Contributors; 1 Fluorous Chemistry: Scope and Definition; 1.1 The Birth of a Term; 1.2 The Definition of Fluorous Today; 1.3 Other Definitions within the Fluorous Repertoire; 1.4 Present Scope of Fluorous Chemistry; References; 2 A Personal View of the History of Fluorous Chemistry; References; 3 Fluorous Solvents and Related Media; 3.1 Introductory Remarks; 3.2 Commercial Fluorous Solvents; 3.3 Related Solvents and Media; 3.3.1 Amphiphilic or Hybrid Solvents; 3.3.2 Fluorous Ionic Liquids; 3.3.3 ""Faux Fluorous"" Solvents
3.3.4 Fluorous Greases3.3.5 Bonded Fluorous Phases; 3.4 Polarities of Fluorous Solvents; 3.5 Solubilities of Solutes in Fluorous Solvents; 3.5.1 General Aspects; 3.5.2 Gas Solubilities; 3.6 Fluorous/Non-fluorous Solvent Miscibilities; 3.7 Special Reactivity Phenomena in Fluorous Solvents; References; 4 Strategies for the Recovery of Fluorous Catalysts and Reagents: Design and Evaluation; 4.1 Introduction; Basic Recycling Concepts; 4.2 Fluorous/Non-Fluorous Liquid/Liquid Biphase Catalysis; 4.3 Fluorous Catalysis in Amphiphilic or Hybrid Solvents 4.4 Fluorous Catalysis Without Non-Fluorous Solvents4.5 Fluorous Catalysis Without Fluorous Solvents; 4.5.1 Thermomorphic Catalysts; 4.5.2 Other Approaches; 4.6 Fluorous Catalysis Without Solvents; 4.7 Recovery of Fluorous Catalysts using Supports; 4.8 Criteria for Recoverability; 4.8.1 Yield as a Function of Cycle; 4.8.2 TOF as a Function of Cycle; 4.8.3 Catalyst Inventory; 4.9 Slanting Data: How to Make a Non-recoverable Catalyst Appear Recoverable; 4.10 Prospects; References; 5 Ponytails: Structural and Electronic Considerations; 5.1 Introduction; 5.2 Structural Aspects of Ponytails 5.3 NMR Characterization of Ponytails5.4 Electronic Effects: Introduction; 5.5 Electronic Effects: IR Data; 5.6 Electronic Effects: Gas Phase Ionization Data; 5.7 Electronic Effects: Calorimetry; 5.8 Electronic Effects: Solution Equilibria; 5.9 Electronic Effects: Computational Data; 5.10 Electronic Effects: Reactivity; 5.11 Electronic Effects: Additional Probes; 5.12 Electronic Effects: Conclusions; References; 6 Partition Coefficients Involving Fluorous Solvents; 6.1 Introduction; 6.2 Literature Data; 6.3 Trends with Respect to Functional Groups; 6.3.1 Non-Aromatic Hydrocarbons 6.3.2 Non-Aromatic Monofunctional Compounds6.3.3 Simple Monoarenes; 6.3.4 Triarylphosphines; 6.3.5 Pyridines; 6.3.6 Metal Complexes; 6.4 General Trends and Special Situations; 6.5 Quantitative Analysis and Prediction of Partition Coefficients; 6.6 Future Directions; 6.7 Sample Experimental Determinations; References; 7 Separations with Fluorous Silica Gel and Related Materials; 7.1 Introduction; 7.1.1 Fluorous Silica Gel; 7.1.2 Types and Sources of Fluorous Silica Gel Materials and Products; 7.2 Fluorous Solid Phase Extraction (FSPE) 7.2.1 Fluorous Solid Phase Extraction and its Relationship to Chromatography and Liquid/Liquid Extraction |
Record Nr. | UNINA-9910144297603321 |
Weinheim, : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook of fluorous chemistry [[electronic resource] /] / John A. Gladysz, Dennis P. Curran, István T. Horváth (Eds.) |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (627 p.) |
Disciplina |
546/.731
547.02 |
Altri autori (Persone) |
GladyszJohn A
CurranDennis P HorváthIstván T |
Soggetto topico |
Fluorine compounds
Fluorine |
ISBN |
1-280-51979-7
9786610519798 3-527-60390-5 3-527-60449-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Handbook of Fluorous Chemistry; Contents; Preface; Contributors; 1 Fluorous Chemistry: Scope and Definition; 1.1 The Birth of a Term; 1.2 The Definition of Fluorous Today; 1.3 Other Definitions within the Fluorous Repertoire; 1.4 Present Scope of Fluorous Chemistry; References; 2 A Personal View of the History of Fluorous Chemistry; References; 3 Fluorous Solvents and Related Media; 3.1 Introductory Remarks; 3.2 Commercial Fluorous Solvents; 3.3 Related Solvents and Media; 3.3.1 Amphiphilic or Hybrid Solvents; 3.3.2 Fluorous Ionic Liquids; 3.3.3 ""Faux Fluorous"" Solvents
3.3.4 Fluorous Greases3.3.5 Bonded Fluorous Phases; 3.4 Polarities of Fluorous Solvents; 3.5 Solubilities of Solutes in Fluorous Solvents; 3.5.1 General Aspects; 3.5.2 Gas Solubilities; 3.6 Fluorous/Non-fluorous Solvent Miscibilities; 3.7 Special Reactivity Phenomena in Fluorous Solvents; References; 4 Strategies for the Recovery of Fluorous Catalysts and Reagents: Design and Evaluation; 4.1 Introduction; Basic Recycling Concepts; 4.2 Fluorous/Non-Fluorous Liquid/Liquid Biphase Catalysis; 4.3 Fluorous Catalysis in Amphiphilic or Hybrid Solvents 4.4 Fluorous Catalysis Without Non-Fluorous Solvents4.5 Fluorous Catalysis Without Fluorous Solvents; 4.5.1 Thermomorphic Catalysts; 4.5.2 Other Approaches; 4.6 Fluorous Catalysis Without Solvents; 4.7 Recovery of Fluorous Catalysts using Supports; 4.8 Criteria for Recoverability; 4.8.1 Yield as a Function of Cycle; 4.8.2 TOF as a Function of Cycle; 4.8.3 Catalyst Inventory; 4.9 Slanting Data: How to Make a Non-recoverable Catalyst Appear Recoverable; 4.10 Prospects; References; 5 Ponytails: Structural and Electronic Considerations; 5.1 Introduction; 5.2 Structural Aspects of Ponytails 5.3 NMR Characterization of Ponytails5.4 Electronic Effects: Introduction; 5.5 Electronic Effects: IR Data; 5.6 Electronic Effects: Gas Phase Ionization Data; 5.7 Electronic Effects: Calorimetry; 5.8 Electronic Effects: Solution Equilibria; 5.9 Electronic Effects: Computational Data; 5.10 Electronic Effects: Reactivity; 5.11 Electronic Effects: Additional Probes; 5.12 Electronic Effects: Conclusions; References; 6 Partition Coefficients Involving Fluorous Solvents; 6.1 Introduction; 6.2 Literature Data; 6.3 Trends with Respect to Functional Groups; 6.3.1 Non-Aromatic Hydrocarbons 6.3.2 Non-Aromatic Monofunctional Compounds6.3.3 Simple Monoarenes; 6.3.4 Triarylphosphines; 6.3.5 Pyridines; 6.3.6 Metal Complexes; 6.4 General Trends and Special Situations; 6.5 Quantitative Analysis and Prediction of Partition Coefficients; 6.6 Future Directions; 6.7 Sample Experimental Determinations; References; 7 Separations with Fluorous Silica Gel and Related Materials; 7.1 Introduction; 7.1.1 Fluorous Silica Gel; 7.1.2 Types and Sources of Fluorous Silica Gel Materials and Products; 7.2 Fluorous Solid Phase Extraction (FSPE) 7.2.1 Fluorous Solid Phase Extraction and its Relationship to Chromatography and Liquid/Liquid Extraction |
Record Nr. | UNINA-9910830242903321 |
Weinheim, : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Modern fluoroorganic chemistry [[electronic resource] ] : synthesis, reactivity, applications / / Peer Kirsch |
Autore | Kirsch Peer |
Edizione | [2nd, completely rev. and enl. ed.] |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2013 |
Descrizione fisica | 1 online resource (402 p.) |
Disciplina |
547.02
547/.02 |
Soggetto topico | Organofluorine compounds |
ISBN |
3-527-65137-3
3-527-65135-7 1-299-40212-7 3-527-65138-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | pt. 1. Synthesis of complex organofluorine compounds -- pt. 2. Fluorous chemistry -- pt. 3. Applications of organofluorine compounds. |
Record Nr. | UNINA-9910139049003321 |
Kirsch Peer | ||
Weinheim, : Wiley-VCH, 2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Modern fluoroorganic chemistry : synthesis, reactivity, applications / / Peer Kirsch |
Autore | Kirsch Peer |
Edizione | [2nd, completely rev. and enl. ed.] |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2013 |
Descrizione fisica | 1 online resource (402 p.) |
Disciplina |
547.02
547/.02 |
Soggetto topico | Organofluorine compounds |
ISBN |
3-527-65137-3
3-527-65135-7 1-299-40212-7 3-527-65138-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | pt. 1. Synthesis of complex organofluorine compounds -- pt. 2. Fluorous chemistry -- pt. 3. Applications of organofluorine compounds. |
Record Nr. | UNINA-9910807831403321 |
Kirsch Peer | ||
Weinheim, : Wiley-VCH, 2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Modern fluoroorganic chemistry [[electronic resource] ] : synthesis, reactivity, applications / / Peer Kirsch |
Autore | Kirsch Peer |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (322 p.) |
Disciplina |
547.02
547.6 |
Soggetto topico | Organofluorine compounds |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-51959-2
9786610519590 3-527-60393-X 3-527-60419-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Modern Fluoroorganic Chemistry; Contents; Preface; List of Abbreviations; 1 Introduction; 1.1 Why Organofluorine Chemistry?; 1.2 History; 1.3 The Basic Materials; 1.3.1 Hydrofluoric Acid; 1.3.2 Fluorine; 1.4 The Unique Properties of Organofluorine Compounds; 1.4.1 Physical Properties; 1.4.2 Chemical Properties; 1.4.3 Ecological Impact; 1.4.3.1 Ozone Depletion by Chlorofluorocarbons; 1.4.3.2 Greenhouse Effect; 1.4.4 Physiological Properties; 1.4.5 Analysis of Fluorochemicals: (19)F NMR Spectroscopy; 2 Synthesis of Complex Organofluorine Compounds; 2.1 Introduction of Fluorine
2.1.1 Perfluorination and Selective Direct Fluorination2.1.2 Electrochemical Fluorination (ECF); 2.1.3 Nucleophilic Fluorination; 2.1.3.1 Finkelstein Exchange; 2.1.3.2 "Naked" Fluoride; 2.1.3.3 Lewis Acid-assisted Fluorination; 2.1.3.4 The "General Fluorine Effect"; 2.1.3.5 Amine-Hydrogen Fluoride and Ether-Hydrogen Fluoride Reagents; 2.1.3.6 Hydrofluorination, Halofluorination, and Epoxide Ring Opening; 2.1.4 Synthesis and Reactivity of Fluoroaromatic Compounds; 2.1.4.1 Synthesis of Fluoroaromatic Compounds; 2.1.4.2 Reductive Aromatization; 2.1.4.3 The Balz-Schiemann Reaction 2.1.4.4 The Fluoroformate Process2.1.4.5 Transition Metal-assisted Oxidative Fluorination; 2.1.4.6 The Halex Process; 2.1.4.7 Think Negative! - "Orthogonal" Reactivity of Perfluoroaromatic and Perfluoroolefinic Systems; 2.1.4.8 The "Special Fluorine Effect"; 2.1.4.9 Aromatic Nucleophilic Sustitution; 2.1.4.10 Activation of the Carbon-Fluorine Bond by Transition Metals; 2.1.4.11 Activation of Fluoroaromatic Compounds by ortho-Metalation; 2.1.5 Transformations of Functional Groups; 2.1.5.1 Hydroxy into Fluoro; 2.1.5.2 Conversion of Carbonyl into gem-Difluoromethylene 2.1.5.3 Carboxyl into Trifluoromethyl2.1.5.4 Oxidative Fluorodesulfuration; 2.1.6 "Electrophilic" Fluorination; 2.1.6.1 Xenon Difluoride; 2.1.6.2 Perchloryl Fluoride and Hypofluorides; 2.1.6.3 "NF"-Reagents; 2.2 Perfluoroalkylation; 2.2.1 Radical Perfluoroalkylation; 2.2.1.1 Structure, Properties, and Reactivity of Perfluoroalkyl Radicals; 2.2.1.2 Preparatively Useful Reactions of Perfluoroalkyl Radicals; 2.2.1.3 "Inverse" Radical Addition of Alkyl Radicals to Perfluoroolefins; 2.2.2 Nucleophilic Perfluoroalkylation; 2.2.2.1 Properties, Stability, and Reactivity of Fluorinated Carbanions 2.2.2.2 Perfluoroalkyl Metal Compounds2.2.2.3 Perfluoroalkyl Silanes; 2.2.3 "Electrophilic" Perfluoroalkylation; 2.2.3.1 Properties and Stability of Fluorinated Carbocations; 2.2.3.2 Aryl Perfluoroalkyl Iodonium Salts; 2.2.3.3 Perfluoroalkyl Sulfonium, Selenonium, Telluronium, and Oxonium Salts; 2.2.4 Difluorocarbene and Fluorinated Cyclopropanes; 2.3 Selected Fluorinated Structures and Reaction Types; 2.3.1 Difluoromethylation and Halodifluoromethylation; 2.3.2 The Perfluoroalkoxy Group; 2.3.3 The Perfluoroalkylthio Group and Sulfur-based Super-electron-withdrawing Groups 2.3.4 The Pentafluorosulfuranyl Group and Related Structures |
Record Nr. | UNINA-9910144297203321 |
Kirsch Peer | ||
Weinheim, : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|