Cluster secondary ion mass spectrometry [[electronic resource] ] : principles and applications / / edited by Christine M. Mahoney |
Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, Inc., 2013 |
Descrizione fisica | 1 online resource (366 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) | MahoneyChristine M |
Collana | Wiley Series on Mass Spectrometry |
Soggetto topico |
Secondary ion mass spectrometry
Mass spectrometry |
ISBN |
1-118-58924-6
1-118-58933-5 1-299-47587-6 1-118-58925-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
CLUSTER SECONDARY ION MASS SPECTROMETRY; CONTENTS; Contributors; About the Editor; 1 AN INTRODUCTION TO CLUSTER SECONDARY ION MASS SPECTROMETRY (CLUSTER SIMS); 1.1 Secondary Ion Mass Spectrometry in a Nutshell; 1.1.1 SIMS Imaging; 1.1.2 SIMS Depth Profiling; 1.2 Basic Cluster SIMS Theory; 1.3 Cluster SIMS: An Early History; 1.3.1 Nonlinear Sputter Yield Enhancements; 1.3.2 Molecular Depth Profiling; 1.4 Recent Developments; 1.5 About this Book; Acknowledgment; References; 2 CLUSTER SIMS OF ORGANIC MATERIALS: THEORETICAL INSIGHTS; 2.1 Introduction
2.2 Molecular Dynamics Simulations of Sputtering with Clusters2.2.1 The Cluster Effect; 2.2.2 Computer Simulations and the Molecular Dynamics ""Experiment""; 2.2.3 Light and Heavy Element Clusters, and the Importance of Mass Matching; 2.2.4 Structural Effects in Organic Materials; 2.2.4.1 Amorphous Molecular Solids and Polymers; 2.2.4.2 Organic Crystals; 2.2.4.3 Thin Organic Layers on Metal Substrates; 2.2.4.4 Hybrid Metal-Organic Samples; 2.2.5 Induced Chemistry; 2.2.6 Multiple Hits and Depth Profiling; 2.2.7 From Small Polyatomic Projectiles to Massive Clusters 2.2.7.1 Light-Element Clusters2.2.7.2 Large Argon Clusters; 2.2.7.3 Massive Gold Clusters; 2.3 Other Models; 2.3.1 Analytical Models: From Linear Collision Cascades to Fluid Dynamics; 2.3.2 Recent Developments and Hybrid Approaches; 2.4 Conclusions; Acknowledgments; References; 3 ION SOURCES USED FOR SECONDARY ION MASS SPECTROMETRY; 3.1 Introduction; 3.2 Research Needs that have Influenced the Development of Primary Ion Sources for Sputtering; 3.3 Functional Aspects of Various Ion Sources; 3.3.1 Energy Spread in the Beam; 3.3.2 Point-Source Ionization; 3.3.3 Stable Emission 3.3.4 Ion Reactivity3.3.5 Source Lifetime; 3.3.6 Penetration Depth and Surface Energy Spread of the Projectile; 3.4 Atomic Ion Sources; 3.4.1 Field Emission; 3.4.2 Radio Frequency (RF) Ionization; 3.4.3 Electron Impact; 3.4.4 Thermal Ionization; 3.4.5 DC-Glow Discharge; 3.4.6 Sputtering; 3.5 Molecular Ion Sources; 3.5.1 Field Emission; 3.5.2 Radio Frequency Discharge; 3.5.3 Electron Impact; 3.5.4 DC-Glow Discharge; 3.5.5 Sputtering; 3.6 Cluster Ion Sources; 3.6.1 Jets and Electron Impact (Massive Gas Clusters); 3.6.2 Field Emission; 3.7 Summary; References 4 SURFACE ANALYSIS OF ORGANIC MATERIALS WITH POLYATOMIC PRIMARY ION SOURCES4.1 Introduction; 4.2 Cluster Sources in Static SIMS; 4.2.1 A Brief Introduction to Static SIMS; 4.2.2 Analysis beyond the Static Limit; 4.2.3 Increased Ion Yields; 4.2.4 Decreased Charging; 4.2.5 Surface Cleaning; 4.3 Experimental Considerations; 4.3.1 When to Employ Cluster Sources as Opposed to Atomic Sources; 4.3.2 Type of Cluster Source Used; 4.3.2.1 Liquid Metal Ion Gun (LMIG); 4.3.2.2 C + 60 for Mass Spectral Analysis and Imaging Applications; 4.3.2.3 The Gas Cluster Ion Beam (GCIB); 4.3.2.4 Au 4+ 400 4.3.2.5 Other Sources |
Record Nr. | UNINA-9910139006703321 |
Hoboken, N.J., : John Wiley & Sons, Inc., 2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cluster secondary ion mass spectrometry : principles and applications / / edited by Christine M. Mahoney |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, Inc., 2013 |
Descrizione fisica | 1 online resource (366 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) | MahoneyChristine M |
Collana | Wiley Series on Mass Spectrometry |
Soggetto topico |
Secondary ion mass spectrometry
Mass spectrometry |
ISBN |
1-118-58924-6
1-118-58933-5 1-299-47587-6 1-118-58925-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
CLUSTER SECONDARY ION MASS SPECTROMETRY; CONTENTS; Contributors; About the Editor; 1 AN INTRODUCTION TO CLUSTER SECONDARY ION MASS SPECTROMETRY (CLUSTER SIMS); 1.1 Secondary Ion Mass Spectrometry in a Nutshell; 1.1.1 SIMS Imaging; 1.1.2 SIMS Depth Profiling; 1.2 Basic Cluster SIMS Theory; 1.3 Cluster SIMS: An Early History; 1.3.1 Nonlinear Sputter Yield Enhancements; 1.3.2 Molecular Depth Profiling; 1.4 Recent Developments; 1.5 About this Book; Acknowledgment; References; 2 CLUSTER SIMS OF ORGANIC MATERIALS: THEORETICAL INSIGHTS; 2.1 Introduction
2.2 Molecular Dynamics Simulations of Sputtering with Clusters2.2.1 The Cluster Effect; 2.2.2 Computer Simulations and the Molecular Dynamics ""Experiment""; 2.2.3 Light and Heavy Element Clusters, and the Importance of Mass Matching; 2.2.4 Structural Effects in Organic Materials; 2.2.4.1 Amorphous Molecular Solids and Polymers; 2.2.4.2 Organic Crystals; 2.2.4.3 Thin Organic Layers on Metal Substrates; 2.2.4.4 Hybrid Metal-Organic Samples; 2.2.5 Induced Chemistry; 2.2.6 Multiple Hits and Depth Profiling; 2.2.7 From Small Polyatomic Projectiles to Massive Clusters 2.2.7.1 Light-Element Clusters2.2.7.2 Large Argon Clusters; 2.2.7.3 Massive Gold Clusters; 2.3 Other Models; 2.3.1 Analytical Models: From Linear Collision Cascades to Fluid Dynamics; 2.3.2 Recent Developments and Hybrid Approaches; 2.4 Conclusions; Acknowledgments; References; 3 ION SOURCES USED FOR SECONDARY ION MASS SPECTROMETRY; 3.1 Introduction; 3.2 Research Needs that have Influenced the Development of Primary Ion Sources for Sputtering; 3.3 Functional Aspects of Various Ion Sources; 3.3.1 Energy Spread in the Beam; 3.3.2 Point-Source Ionization; 3.3.3 Stable Emission 3.3.4 Ion Reactivity3.3.5 Source Lifetime; 3.3.6 Penetration Depth and Surface Energy Spread of the Projectile; 3.4 Atomic Ion Sources; 3.4.1 Field Emission; 3.4.2 Radio Frequency (RF) Ionization; 3.4.3 Electron Impact; 3.4.4 Thermal Ionization; 3.4.5 DC-Glow Discharge; 3.4.6 Sputtering; 3.5 Molecular Ion Sources; 3.5.1 Field Emission; 3.5.2 Radio Frequency Discharge; 3.5.3 Electron Impact; 3.5.4 DC-Glow Discharge; 3.5.5 Sputtering; 3.6 Cluster Ion Sources; 3.6.1 Jets and Electron Impact (Massive Gas Clusters); 3.6.2 Field Emission; 3.7 Summary; References 4 SURFACE ANALYSIS OF ORGANIC MATERIALS WITH POLYATOMIC PRIMARY ION SOURCES4.1 Introduction; 4.2 Cluster Sources in Static SIMS; 4.2.1 A Brief Introduction to Static SIMS; 4.2.2 Analysis beyond the Static Limit; 4.2.3 Increased Ion Yields; 4.2.4 Decreased Charging; 4.2.5 Surface Cleaning; 4.3 Experimental Considerations; 4.3.1 When to Employ Cluster Sources as Opposed to Atomic Sources; 4.3.2 Type of Cluster Source Used; 4.3.2.1 Liquid Metal Ion Gun (LMIG); 4.3.2.2 C + 60 for Mass Spectral Analysis and Imaging Applications; 4.3.2.3 The Gas Cluster Ion Beam (GCIB); 4.3.2.4 Au 4+ 400 4.3.2.5 Other Sources |
Record Nr. | UNINA-9910827678303321 |
Hoboken, N.J., : John Wiley & Sons, Inc., 2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Fundamentals of contemporary mass spectrometry / / Chhabil Dass |
Autore | Dass Chhabil |
Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2007 |
Descrizione fisica | 1 online resource (609 p.) |
Disciplina | 543/.65 |
Collana | Wiley-Interscience series on mass spectrometry |
Soggetto topico |
Mass spectrometry
Spectrum analysis - Instruments Molecular spectroscopy Biomolecules - Analysis |
ISBN |
1-280-85508-8
9786610855087 0-470-11849-0 0-470-11848-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Instrumentation -- Basics of mass spectrometry -- Modes of ionization -- Mass analysis and ion detection -- Tandem mass spectrometry -- Hyphenated separation techniques -- Organic and inorganic mass spectrometry -- Organic mass spectrometry -- Inorganic mass spectrometry -- Biological mass spectrometry -- Proteins and peptides : structure determination -- Proteins and peptides : posttranslational modifications -- Proteins and peptides : higher-order structures -- Characterization of oligosaccharides -- Characterization of lipids -- Structure determination of oligonucleotides -- Quantitative analysis -- Miscellaneous topics. |
Record Nr. | UNINA-9910143583903321 |
Dass Chhabil | ||
Hoboken, N.J., : Wiley-Interscience, c2007 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook for highly charged ion spectroscopic research / / [edited by] Yaming Zou, Roger Hutton |
Pubbl/distr/stampa | Boca Raton : , : Taylor & Francis, , 2012 |
Descrizione fisica | 1 online resource (452 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) |
ZouYaming
HuttonR (Roger) |
Soggetto topico |
Ion mobility spectroscopy
Atomic structure Quantum electrodynamics Parity nonconservation |
Soggetto genere / forma | Electronic books. |
ISBN |
0-429-14336-2
1-4200-7905-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Dedication; Contents; Preface; Editors; Contributors; Part I: Tools and Techniques; 1. Light Sources for Atomic Spectroscopy; 2. Electron Beam Ion Traps: Principles and Applications to Highly Charged Ion Spectroscopy; 3. Spectroscopic Instruments; 4. Crystal Spectrometers; 5. CCD Detectors; 6. Microchannel-Plate Detectors in Atomic Physics Applications; 7. Coincidence Techniques in Atomic Collisions; 8. Isoelectronic Trends in Atomic Properties; Part II: Investigations of Atomic Structure and Applications; 9. Experimental Investigation of the Structure of Highly Ionized Atoms
10. Atomic Lifetime Measurements of Highly Charged Ions11. Importance of Tungsten Spectroscopy to the Success of ITER; 12. X-Ray Emission Spectroscopy and Diagnostics of Nonequilibrium Fusion and Laser-Produced Plasmas; 13. Short-Wavelength Free Electron Lasers; 14. QED Theory of Highly Charged Ions; 15. Parity Nonconservation Effects in the Highly Charged Ions |
Record Nr. | UNINA-9910457691303321 |
Boca Raton : , : Taylor & Francis, , 2012 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook for highly charged ion spectroscopic research / / [edited by] Yaming Zou, Roger Hutton |
Pubbl/distr/stampa | Boca Raton : , : Taylor & Francis, , 2012 |
Descrizione fisica | 1 online resource (452 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) |
ZouYaming
HuttonR (Roger) |
Soggetto topico |
Ion mobility spectroscopy
Atomic structure Quantum electrodynamics Parity nonconservation |
ISBN |
0-429-14336-2
1-4200-7905-0 |
Classificazione | SCI074000SCI055000SCI077000 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Dedication; Contents; Preface; Editors; Contributors; Part I: Tools and Techniques; 1. Light Sources for Atomic Spectroscopy; 2. Electron Beam Ion Traps: Principles and Applications to Highly Charged Ion Spectroscopy; 3. Spectroscopic Instruments; 4. Crystal Spectrometers; 5. CCD Detectors; 6. Microchannel-Plate Detectors in Atomic Physics Applications; 7. Coincidence Techniques in Atomic Collisions; 8. Isoelectronic Trends in Atomic Properties; Part II: Investigations of Atomic Structure and Applications; 9. Experimental Investigation of the Structure of Highly Ionized Atoms
10. Atomic Lifetime Measurements of Highly Charged Ions11. Importance of Tungsten Spectroscopy to the Success of ITER; 12. X-Ray Emission Spectroscopy and Diagnostics of Nonequilibrium Fusion and Laser-Produced Plasmas; 13. Short-Wavelength Free Electron Lasers; 14. QED Theory of Highly Charged Ions; 15. Parity Nonconservation Effects in the Highly Charged Ions |
Record Nr. | UNINA-9910781583003321 |
Boca Raton : , : Taylor & Francis, , 2012 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook for highly charged ion spectroscopic research / / [edited by] Yaming Zou, Roger Hutton |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Boca Raton, : Taylor & Francis, 2011 |
Descrizione fisica | 1 online resource (452 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) |
ZouYaming
HuttonR (Roger) |
Soggetto topico |
Ion mobility spectroscopy
Atomic structure Quantum electrodynamics Parity nonconservation |
ISBN |
0-429-14336-2
1-4200-7905-0 |
Classificazione | SCI074000SCI055000SCI077000 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Dedication; Contents; Preface; Editors; Contributors; Part I: Tools and Techniques; 1. Light Sources for Atomic Spectroscopy; 2. Electron Beam Ion Traps: Principles and Applications to Highly Charged Ion Spectroscopy; 3. Spectroscopic Instruments; 4. Crystal Spectrometers; 5. CCD Detectors; 6. Microchannel-Plate Detectors in Atomic Physics Applications; 7. Coincidence Techniques in Atomic Collisions; 8. Isoelectronic Trends in Atomic Properties; Part II: Investigations of Atomic Structure and Applications; 9. Experimental Investigation of the Structure of Highly Ionized Atoms
10. Atomic Lifetime Measurements of Highly Charged Ions11. Importance of Tungsten Spectroscopy to the Success of ITER; 12. X-Ray Emission Spectroscopy and Diagnostics of Nonequilibrium Fusion and Laser-Produced Plasmas; 13. Short-Wavelength Free Electron Lasers; 14. QED Theory of Highly Charged Ions; 15. Parity Nonconservation Effects in the Highly Charged Ions |
Record Nr. | UNINA-9910827460303321 |
Boca Raton, : Taylor & Francis, 2011 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook on mass spectrometry [[electronic resource] ] : instrumentation, data and analysis, and applications / / J.K. Lang, editor |
Pubbl/distr/stampa | New York, : Nova Science Publishers, c2009 |
Descrizione fisica | 1 online resource (545 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) | LangJ. K |
Collana | Advances in chemistry research series |
Soggetto topico |
Mass spectrometry
Chemistry, Analytic |
Soggetto genere / forma | Electronic books. |
ISBN | 1-61209-692-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""HANDBOOK ON MASS SPECTROMETRY:INSTRUMENTATION, DATA AND ANALYSIS, AND APPLICATIONS""; ""CONTENTS""; ""PREFACE""; ""MASS SPECTROMETRIC CHARACTERIZATION OF ORGANOMETALLIC COMPOUNDS""; ""ABSTRACT""; ""1. INTRODUCTION""; ""2. IONIZATION TECHNIQUES""; ""3. MASS ANALYZERS""; ""4. BASIC IONIZATION MECHANISMS OF ORGANOMETALLICS""; ""5. MASS SPECTROMETRY OF INDIVIDUAL ORGANOMETALLIC CLASSES""; ""5.1. Main Group Organometallic Compounds""; ""Simple main group organometallic compounds""; ""Organotin compounds""; ""Organolead compounds""; ""Organogermanium compounds""
""Organoarsenic, organoantimony and organobismuth compounds""""Organoboron compounds""; ""Organoaluminum, organogallium and organoindium compounds""; ""Organoselenium and organotellurium compounds""; ""Organosilicon compounds""; ""5.2. Transition Metal Organometallic Compounds""; ""Metallocenes and related compounds""; ""Transition metal organometallic compounds containing covalent carbon-metal bond""; ""Heteropolymetallic complexes""; ""5.3. Organometallics Compounds Containing Lanthanoids""; ""6. CONCLUSION""; ""ACKNOWLEDGMENTS""; ""7. REFERENCES""; ""LC-MS BASED METABOLOMICS"" ""ABSTRACT""""1. METABOLOMICS?""; ""1.1. The Positioning of Metabolomics in Research""; ""1.2. Challenges in Metabolomics Approaches""; ""1.3. Mass Spectrometry in Metabolomics Research""; ""2. STAGES IN AN LC-MS BASED METABOLOMICS ANALYSIS""; ""2.1. Sample Collection and Sample Storage""; ""2.2. Sample Homogenisation/Extraction/Deproteinisation""; ""2.3. Liquid Chromatography (LC)""; ""2.4. The Ionisation Process as an Interface between LC and MS: Focus on Matrix Effect""; ""2.5. Mass Spectrometry""; ""2.6. Data Handling""; ""2.6.1. Data processing""; ""2.6.1.1. Filtering"" ""2.6.1.2. Feature/peak detection""""2.6.1.3. Alignment""; ""2.6.1.4. Normalisation""; ""2.6.2. Data analysis""; ""2.6.2.1. Principal component analysis (PCA) ""; ""2.6.2.2 Partial least-squares projections to latens structures (PLS)""; ""2.6.2.3. O-PLS""; ""2.7. Metabolite Identification""; ""3. CONCLUSION""; ""REFERENCES""; ""BIOMARKER DISCOVERY FOR CANCER DIAGNOSIS USING SERUM PROTEOMIC ANALYSIS:FROM BASIC RESEARCH TO CLINICAL APPLICATION""; ""ABSTRACT""; ""INTRODUCTION""; ""1. PROTEOMIC ANALYSIS OF SERUM/PLASMA IS EFFECTIVE TO SEARCH FOR CANCER DIAGNOSTIC MARKERS"" ""1.1. Characteristics of Global Analyses and Diagnostic Availability of Biomarkers""""1.2. Advantages of Proteomic Analysis in the Search for Diagnostic Biomarkers""; ""1.3. Specimen""; ""2. SEPARATION TECHNOLOGIES IN PROTEOMIC ANALYSIS""; ""2.1. 2D-DIGE""; ""2.2. Protein Chip Array®""; ""2.3. ClinProt®""; ""2.4. Shotgun Proteomics Using LC""; ""3. MASS SPECTROMETRY""; ""3.1. Fundamentals of MS""; ""3.2. Ionization Methods""; ""3.3. Mass Analyzers""; ""3.4. Types of MS Used in Proteomic Analysis""; ""4. IDENTIFICATION OF PROTEINS/PEPTIDES USING MS"" ""4.1. Protein Identification by Peptide Mass Fingerprinting"" |
Record Nr. | UNINA-9910465689103321 |
New York, : Nova Science Publishers, c2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook on mass spectrometry [[electronic resource] ] : instrumentation, data and analysis, and applications / / J.K. Lang, editor |
Pubbl/distr/stampa | New York, : Nova Science Publishers, c2009 |
Descrizione fisica | 1 online resource (545 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) | LangJ. K |
Collana | Advances in chemistry research series |
Soggetto topico |
Mass spectrometry
Chemistry, Analytic |
ISBN | 1-61209-692-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""HANDBOOK ON MASS SPECTROMETRY:INSTRUMENTATION, DATA AND ANALYSIS, AND APPLICATIONS""; ""CONTENTS""; ""PREFACE""; ""MASS SPECTROMETRIC CHARACTERIZATION OF ORGANOMETALLIC COMPOUNDS""; ""ABSTRACT""; ""1. INTRODUCTION""; ""2. IONIZATION TECHNIQUES""; ""3. MASS ANALYZERS""; ""4. BASIC IONIZATION MECHANISMS OF ORGANOMETALLICS""; ""5. MASS SPECTROMETRY OF INDIVIDUAL ORGANOMETALLIC CLASSES""; ""5.1. Main Group Organometallic Compounds""; ""Simple main group organometallic compounds""; ""Organotin compounds""; ""Organolead compounds""; ""Organogermanium compounds""
""Organoarsenic, organoantimony and organobismuth compounds""""Organoboron compounds""; ""Organoaluminum, organogallium and organoindium compounds""; ""Organoselenium and organotellurium compounds""; ""Organosilicon compounds""; ""5.2. Transition Metal Organometallic Compounds""; ""Metallocenes and related compounds""; ""Transition metal organometallic compounds containing covalent carbon-metal bond""; ""Heteropolymetallic complexes""; ""5.3. Organometallics Compounds Containing Lanthanoids""; ""6. CONCLUSION""; ""ACKNOWLEDGMENTS""; ""7. REFERENCES""; ""LC-MS BASED METABOLOMICS"" ""ABSTRACT""""1. METABOLOMICS?""; ""1.1. The Positioning of Metabolomics in Research""; ""1.2. Challenges in Metabolomics Approaches""; ""1.3. Mass Spectrometry in Metabolomics Research""; ""2. STAGES IN AN LC-MS BASED METABOLOMICS ANALYSIS""; ""2.1. Sample Collection and Sample Storage""; ""2.2. Sample Homogenisation/Extraction/Deproteinisation""; ""2.3. Liquid Chromatography (LC)""; ""2.4. The Ionisation Process as an Interface between LC and MS: Focus on Matrix Effect""; ""2.5. Mass Spectrometry""; ""2.6. Data Handling""; ""2.6.1. Data processing""; ""2.6.1.1. Filtering"" ""2.6.1.2. Feature/peak detection""""2.6.1.3. Alignment""; ""2.6.1.4. Normalisation""; ""2.6.2. Data analysis""; ""2.6.2.1. Principal component analysis (PCA) ""; ""2.6.2.2 Partial least-squares projections to latens structures (PLS)""; ""2.6.2.3. O-PLS""; ""2.7. Metabolite Identification""; ""3. CONCLUSION""; ""REFERENCES""; ""BIOMARKER DISCOVERY FOR CANCER DIAGNOSIS USING SERUM PROTEOMIC ANALYSIS:FROM BASIC RESEARCH TO CLINICAL APPLICATION""; ""ABSTRACT""; ""INTRODUCTION""; ""1. PROTEOMIC ANALYSIS OF SERUM/PLASMA IS EFFECTIVE TO SEARCH FOR CANCER DIAGNOSTIC MARKERS"" ""1.1. Characteristics of Global Analyses and Diagnostic Availability of Biomarkers""""1.2. Advantages of Proteomic Analysis in the Search for Diagnostic Biomarkers""; ""1.3. Specimen""; ""2. SEPARATION TECHNOLOGIES IN PROTEOMIC ANALYSIS""; ""2.1. 2D-DIGE""; ""2.2. Protein Chip Array®""; ""2.3. ClinProt®""; ""2.4. Shotgun Proteomics Using LC""; ""3. MASS SPECTROMETRY""; ""3.1. Fundamentals of MS""; ""3.2. Ionization Methods""; ""3.3. Mass Analyzers""; ""3.4. Types of MS Used in Proteomic Analysis""; ""4. IDENTIFICATION OF PROTEINS/PEPTIDES USING MS"" ""4.1. Protein Identification by Peptide Mass Fingerprinting"" |
Record Nr. | UNINA-9910791771703321 |
New York, : Nova Science Publishers, c2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook on mass spectrometry : instrumentation, data and analysis, and applications / / J.K. Lang, editor |
Edizione | [1st ed.] |
Pubbl/distr/stampa | New York, : Nova Science Publishers, c2009 |
Descrizione fisica | 1 online resource (545 p.) |
Disciplina | 543/.65 |
Altri autori (Persone) | LangJ. K |
Collana | Advances in chemistry research series |
Soggetto topico |
Mass spectrometry
Chemistry, Analytic |
ISBN | 1-61209-692-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""HANDBOOK ON MASS SPECTROMETRY:INSTRUMENTATION, DATA AND ANALYSIS, AND APPLICATIONS""; ""CONTENTS""; ""PREFACE""; ""MASS SPECTROMETRIC CHARACTERIZATION OF ORGANOMETALLIC COMPOUNDS""; ""ABSTRACT""; ""1. INTRODUCTION""; ""2. IONIZATION TECHNIQUES""; ""3. MASS ANALYZERS""; ""4. BASIC IONIZATION MECHANISMS OF ORGANOMETALLICS""; ""5. MASS SPECTROMETRY OF INDIVIDUAL ORGANOMETALLIC CLASSES""; ""5.1. Main Group Organometallic Compounds""; ""Simple main group organometallic compounds""; ""Organotin compounds""; ""Organolead compounds""; ""Organogermanium compounds""
""Organoarsenic, organoantimony and organobismuth compounds""""Organoboron compounds""; ""Organoaluminum, organogallium and organoindium compounds""; ""Organoselenium and organotellurium compounds""; ""Organosilicon compounds""; ""5.2. Transition Metal Organometallic Compounds""; ""Metallocenes and related compounds""; ""Transition metal organometallic compounds containing covalent carbon-metal bond""; ""Heteropolymetallic complexes""; ""5.3. Organometallics Compounds Containing Lanthanoids""; ""6. CONCLUSION""; ""ACKNOWLEDGMENTS""; ""7. REFERENCES""; ""LC-MS BASED METABOLOMICS"" ""ABSTRACT""""1. METABOLOMICS?""; ""1.1. The Positioning of Metabolomics in Research""; ""1.2. Challenges in Metabolomics Approaches""; ""1.3. Mass Spectrometry in Metabolomics Research""; ""2. STAGES IN AN LC-MS BASED METABOLOMICS ANALYSIS""; ""2.1. Sample Collection and Sample Storage""; ""2.2. Sample Homogenisation/Extraction/Deproteinisation""; ""2.3. Liquid Chromatography (LC)""; ""2.4. The Ionisation Process as an Interface between LC and MS: Focus on Matrix Effect""; ""2.5. Mass Spectrometry""; ""2.6. Data Handling""; ""2.6.1. Data processing""; ""2.6.1.1. Filtering"" ""2.6.1.2. Feature/peak detection""""2.6.1.3. Alignment""; ""2.6.1.4. Normalisation""; ""2.6.2. Data analysis""; ""2.6.2.1. Principal component analysis (PCA) ""; ""2.6.2.2 Partial least-squares projections to latens structures (PLS)""; ""2.6.2.3. O-PLS""; ""2.7. Metabolite Identification""; ""3. CONCLUSION""; ""REFERENCES""; ""BIOMARKER DISCOVERY FOR CANCER DIAGNOSIS USING SERUM PROTEOMIC ANALYSIS:FROM BASIC RESEARCH TO CLINICAL APPLICATION""; ""ABSTRACT""; ""INTRODUCTION""; ""1. PROTEOMIC ANALYSIS OF SERUM/PLASMA IS EFFECTIVE TO SEARCH FOR CANCER DIAGNOSTIC MARKERS"" ""1.1. Characteristics of Global Analyses and Diagnostic Availability of Biomarkers""""1.2. Advantages of Proteomic Analysis in the Search for Diagnostic Biomarkers""; ""1.3. Specimen""; ""2. SEPARATION TECHNOLOGIES IN PROTEOMIC ANALYSIS""; ""2.1. 2D-DIGE""; ""2.2. Protein Chip Array®""; ""2.3. ClinProt®""; ""2.4. Shotgun Proteomics Using LC""; ""3. MASS SPECTROMETRY""; ""3.1. Fundamentals of MS""; ""3.2. Ionization Methods""; ""3.3. Mass Analyzers""; ""3.4. Types of MS Used in Proteomic Analysis""; ""4. IDENTIFICATION OF PROTEINS/PEPTIDES USING MS"" ""4.1. Protein Identification by Peptide Mass Fingerprinting"" |
Record Nr. | UNINA-9910823555203321 |
New York, : Nova Science Publishers, c2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Inductively coupled plasma spectrometry and its applications [[electronic resource] /] / edited by Steve J. Hill |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Oxford, : Blackwell, 2007 |
Descrizione fisica | 1 online resource (447 p.) |
Disciplina |
543.65
543/.65 643.65 |
Collana | Analytical chemistry |
Soggetto topico |
Inductively coupled plasma spectrometry
Inductively coupled plasma mass spectrometry |
ISBN |
1-280-74867-2
9786610748679 0-470-98879-7 9780470988794 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Inductively Coupled Plasma Spectrometry and its Applications; Contents; Contributors; Preface; 1 Introduction - A Forward-Looking Perspective; 1.1 Introduction; 1.2 Extrapolation of past and current trends; 1.2.1 Influences from science and technology; 1.2.2 Influences from society, politics, and the economy; 1.2.3 Past and current trends in atomic spectrometry; 1.3 Influence of technology transfer; 1.3.1 Electronics and data manipulation; 1.3.2 Metal-binding structures; 1.3.3 Novel separation methods; 1.3.4 Detector technologies; 1.4 Strengths and weaknesses of ICP-AES and ICP-MS
1.4.1 Strengths and weaknesses of ICP-AES1.4.2 Strengths and weaknesses of ICP-MS; 1.4.3 ICP limitations; 1.5 Potential directions in ICP spectrometry; 1.6 Concluding considerations; References; 2 Fundamental Principles of Inductively Coupled Plasmas; 2.1 Principles to inductively coupled plasma generation; 2.2 Equilibrium in a plasma; 2.3 Line intensities; 2.4 Line profiles; 2.5 Temperature definitions; 2.6 Temperature measurements; 2.6.1 Kinetic temperature measurement; 2.6.2 Rotational temperature measurement; 2.6.3 Excitation temperature; 2.6.3.1 Boltzmann plot; 2.6.3.2 Line pair method 2.6.4 Electron temperature2.7 Electron number density measurement; 2.8 Ionic to atomic line intensity ratio; 2.9 Active methods; 2.9.1 Laser-induced fluorescence; 2.9.2 Light scattering; 2.10 Spatial profiles; 2.11 Temperature and electron number densities observed in analytical ICPs; 2.12 Plasma perturbation; 2.13 Multiline diagnostics; References; 3 Basic Concepts and Instrumentation for Plasma Spectrometry; 3.1 Detection limits and sensitivity; 3.1.1 ICP-Atomic emission spectrometry; 3.1.2 Limits of detection; 3.1.3 Axial systems; 3.1.4 The sample introduction system; 3.1.5 Detectors 3.2 Accuracy and precision3.2.1 Instrumental drift; 3.2.2 Matrix effects; 3.2.3 Plasma effects; 3.2.4 Spectral effects, interferences and background correction; 3.2.5 Dynamic range; 3.2.6 ICP-MS; 3.3 Multi-element capability and selectivity; 3.4 Instrumental overview; 3.5 Radio-frequency generators; 3.6 Torches; 3.7 Spectrometers; 3.7.1 Line isolation; 3.7.2 Monochromators; 3.7.3 Polychromators; 3.8 Detectors; 3.8.1 Photomultiplier tubes; 3.8.2 Solid-state detectors; 3.9 Nebulisers and spray chambers; 3.10 Read-out devices, instrument control and data processing; 3.11 Radial and axial plasmas 3.12 Instrumentation for high-resolution spectrometry3.13 Micro-plasmas and plasma on a chip; References; 4 Aerosol Generation and Sample Transport; 4.1 Introduction; 4.2 Sample introduction characteristics of the ICP source; 4.2.1 Particle size distribution; 4.2.2 Plasma loading; 4.3 Liquid aerosol generation; 4.3.1 Pneumatic nebulization; 4.3.1.1 Pneumatic nebulizer designs; 4.3.1.2 Ultrasonic nebulizers; 4.3.1.3 Alternative nebulizer designs; 4.3.2 Spray chambers; 4.3.2.1 Mode of operation; 4.3.2.2 Practical designs of spray chambers; 4.3.2.3 Desolvation; 4.3.3 Chromatographic interfaces 4.4 Vapour generation |
Record Nr. | UNISA-996213067903316 |
Oxford, : Blackwell, 2007 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. di Salerno | ||
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