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MARC Lista (tabellare)
Dynamic mass spectrometry / edited by Dennis Price and J.F.J. Todd
Dynamic mass spectrometry / edited by Dennis Price and J.F.J. Todd
Pubbl/distr/stampa London ; Philadelphia : Heyden and Son Ltd, 1970-1981
Descrizione fisica 6 v. ill. 27 cm
Disciplina 543/.0873
Altri autori (Persone) Price, Dennis
Todd, John F. J.
Soggetto topico Mass spectrometry - Congresses
Classificazione 53.0.68
LC QC451
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNISALENTO-991000899269707536
London ; Philadelphia : Heyden and Son Ltd, 1970-1981
Materiale a stampa
Lo trovi qui: Univ. del Salento
Opac: Controlla la disponibilità qui
Gas chromatography and mass spectrometry [[electronic resource] ] : a practical guide / / Fulton G. Kitson, Barbara S. Larsen, Charles N. McEwen
Gas chromatography and mass spectrometry [[electronic resource] ] : a practical guide / / Fulton G. Kitson, Barbara S. Larsen, Charles N. McEwen
Autore Kitson Fulton G
Pubbl/distr/stampa San Diego, : Academic Press, c1996
Descrizione fisica 1 online resource (xii, 381 pages) : illustrations
Disciplina 543/.0873
Altri autori (Persone) LarsenBarbara Seliger
McEwenCharles N. <1942->
Soggetto topico Gas chromatography
Mass spectrometry
Soggetto genere / forma Electronic books.
ISBN 1-281-01886-4
9786611018863
0-08-053232-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I: The Fundamentals of GC/MS; Chapter 1. What Is GC/MS?; Chapter 2. Interpretation of Mass Spectra; Chapter 3. Quantitative GC/MS; Part II: GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types; Chapter 4. Acids; Chapter 5. Alcohols; Chapter 6. Aldehydes; Chapter 7. Amides; Chapter 8. Amines; Chapter 9. Amino Acids; Chapter 10. Common Contaminants; Chapter 11. Drugs and Their Metabolites; Chapter 12. Esters; Chapter 13. Ethers
Chapter 14. Fluorinated CompoundsChapter 15. Gases; Chapter 16. Glycols; Chapter 17. Halogenated Compounds (Other Than Fluorinated); Chapter 18. Hydrocarbons; Chapter 19. Isocyanates; Chapter 20. Ketones; Chapter 21. Nitriles; Chapter 22. Nitroaromatics; Chapter 23. Nitrogen-Containing Heterocyclics; Chapter 24. Nucleosides (TMS Derivatives); Chapter 25. Pesticides; Chapter 26. Phenols; Chapter 27. Phosphorus Compounds; Chapter 28. Plasticizers and Other Polymer Additives (Including Phthalates); Chapter 29. Prostaglandins (MO-TMS Derivatives); Chapter 30. Solvents and Their Impurities
Chapter 31. SteroidsChapter 32. Sugars (Monosaccharides); Chapter 33. Sulfur Compounds; Part III: Ions for Determining Unknown Structures; Part IV: Appendices; Appendix 1. Definitions of Terms Related to Gas Chromatography; Appendix 2. Tips for Gas Chromatography; Appendix 3. Derivatives Found Useful in GC/MS; Appendix 4. Cross-Index Chart for GC Phases; Appendix 5. McReynolds' Constants; Appendix 6. Simple GC Troubleshooting; Appendix 7. Definitions of Terms Related to Mass Spectrometry; Appendix 8. Tips and Troubleshooting for Mass Spectrometers
Appendix 9. Atomic Masses and Isotope AbundancesAppendix 10. Structurally Significant McLafferty Rearrangement Ions; Appendix 11. Isotope Patterns for Chlorine and Bromine; Appendix 12. Mixtures for Determining Mass Spectral Resolution; Index
Record Nr. UNINA-9910457968803321
Kitson Fulton G  
San Diego, : Academic Press, c1996
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Gas chromatography and mass spectrometry [[electronic resource] ] : a practical guide / / Fulton G. Kitson, Barbara S. Larsen, Charles N. McEwen
Gas chromatography and mass spectrometry [[electronic resource] ] : a practical guide / / Fulton G. Kitson, Barbara S. Larsen, Charles N. McEwen
Autore Kitson Fulton G
Pubbl/distr/stampa San Diego, : Academic Press, c1996
Descrizione fisica 1 online resource (xii, 381 pages) : illustrations
Disciplina 543/.0873
Altri autori (Persone) LarsenBarbara Seliger
McEwenCharles N. <1942->
Soggetto topico Gas chromatography
Mass spectrometry
ISBN 1-281-01886-4
9786611018863
0-08-053232-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I: The Fundamentals of GC/MS; Chapter 1. What Is GC/MS?; Chapter 2. Interpretation of Mass Spectra; Chapter 3. Quantitative GC/MS; Part II: GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types; Chapter 4. Acids; Chapter 5. Alcohols; Chapter 6. Aldehydes; Chapter 7. Amides; Chapter 8. Amines; Chapter 9. Amino Acids; Chapter 10. Common Contaminants; Chapter 11. Drugs and Their Metabolites; Chapter 12. Esters; Chapter 13. Ethers
Chapter 14. Fluorinated CompoundsChapter 15. Gases; Chapter 16. Glycols; Chapter 17. Halogenated Compounds (Other Than Fluorinated); Chapter 18. Hydrocarbons; Chapter 19. Isocyanates; Chapter 20. Ketones; Chapter 21. Nitriles; Chapter 22. Nitroaromatics; Chapter 23. Nitrogen-Containing Heterocyclics; Chapter 24. Nucleosides (TMS Derivatives); Chapter 25. Pesticides; Chapter 26. Phenols; Chapter 27. Phosphorus Compounds; Chapter 28. Plasticizers and Other Polymer Additives (Including Phthalates); Chapter 29. Prostaglandins (MO-TMS Derivatives); Chapter 30. Solvents and Their Impurities
Chapter 31. SteroidsChapter 32. Sugars (Monosaccharides); Chapter 33. Sulfur Compounds; Part III: Ions for Determining Unknown Structures; Part IV: Appendices; Appendix 1. Definitions of Terms Related to Gas Chromatography; Appendix 2. Tips for Gas Chromatography; Appendix 3. Derivatives Found Useful in GC/MS; Appendix 4. Cross-Index Chart for GC Phases; Appendix 5. McReynolds' Constants; Appendix 6. Simple GC Troubleshooting; Appendix 7. Definitions of Terms Related to Mass Spectrometry; Appendix 8. Tips and Troubleshooting for Mass Spectrometers
Appendix 9. Atomic Masses and Isotope AbundancesAppendix 10. Structurally Significant McLafferty Rearrangement Ions; Appendix 11. Isotope Patterns for Chlorine and Bromine; Appendix 12. Mixtures for Determining Mass Spectral Resolution; Index
Record Nr. UNINA-9910784534603321
Kitson Fulton G  
San Diego, : Academic Press, c1996
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Gas chromatography and mass spectrometry : a practical guide / / Fulton G. Kitson, Barbara S. Larsen, Charles N. McEwen
Gas chromatography and mass spectrometry : a practical guide / / Fulton G. Kitson, Barbara S. Larsen, Charles N. McEwen
Autore Kitson Fulton G
Edizione [1st ed.]
Pubbl/distr/stampa San Diego, : Academic Press, c1996
Descrizione fisica 1 online resource (xii, 381 pages) : illustrations
Disciplina 543/.0873
543.0873
Altri autori (Persone) LarsenBarbara Seliger
McEwenCharles N. <1942->
Soggetto topico Gas chromatography
Mass spectrometry
ISBN 1-281-01886-4
9786611018863
0-08-053232-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I: The Fundamentals of GC/MS; Chapter 1. What Is GC/MS?; Chapter 2. Interpretation of Mass Spectra; Chapter 3. Quantitative GC/MS; Part II: GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types; Chapter 4. Acids; Chapter 5. Alcohols; Chapter 6. Aldehydes; Chapter 7. Amides; Chapter 8. Amines; Chapter 9. Amino Acids; Chapter 10. Common Contaminants; Chapter 11. Drugs and Their Metabolites; Chapter 12. Esters; Chapter 13. Ethers
Chapter 14. Fluorinated CompoundsChapter 15. Gases; Chapter 16. Glycols; Chapter 17. Halogenated Compounds (Other Than Fluorinated); Chapter 18. Hydrocarbons; Chapter 19. Isocyanates; Chapter 20. Ketones; Chapter 21. Nitriles; Chapter 22. Nitroaromatics; Chapter 23. Nitrogen-Containing Heterocyclics; Chapter 24. Nucleosides (TMS Derivatives); Chapter 25. Pesticides; Chapter 26. Phenols; Chapter 27. Phosphorus Compounds; Chapter 28. Plasticizers and Other Polymer Additives (Including Phthalates); Chapter 29. Prostaglandins (MO-TMS Derivatives); Chapter 30. Solvents and Their Impurities
Chapter 31. SteroidsChapter 32. Sugars (Monosaccharides); Chapter 33. Sulfur Compounds; Part III: Ions for Determining Unknown Structures; Part IV: Appendices; Appendix 1. Definitions of Terms Related to Gas Chromatography; Appendix 2. Tips for Gas Chromatography; Appendix 3. Derivatives Found Useful in GC/MS; Appendix 4. Cross-Index Chart for GC Phases; Appendix 5. McReynolds' Constants; Appendix 6. Simple GC Troubleshooting; Appendix 7. Definitions of Terms Related to Mass Spectrometry; Appendix 8. Tips and Troubleshooting for Mass Spectrometers
Appendix 9. Atomic Masses and Isotope AbundancesAppendix 10. Structurally Significant McLafferty Rearrangement Ions; Appendix 11. Isotope Patterns for Chlorine and Bromine; Appendix 12. Mixtures for Determining Mass Spectral Resolution; Index
Record Nr. UNINA-9910827538403321
Kitson Fulton G  
San Diego, : Academic Press, c1996
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mass Spectrometry : Principles and Applications
Mass Spectrometry : Principles and Applications
Autore de Hoffmann Edmond
Edizione [3rd ed.]
Pubbl/distr/stampa Newy York : , : John Wiley & Sons, Incorporated, , 2007
Descrizione fisica 1 online resource (503 pages)
Disciplina 543/.0873
Altri autori (Persone) StroobantVincent
De HoffmannEdmond
Soggetto topico Mass spectrometry
Soggetto genere / forma Electronic books.
ISBN 9780470512135
9780470033104
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Mass Spectrometry -- Contents -- Preface -- Introduction -- Principles -- Diagram of a Mass Spectrometer -- History -- Ion Free Path -- 1 Ion Sources -- 1.1 Electron Ionization -- 1.2 Chemical Ionization -- 1.2.1 Proton Transfer -- 1.2.2 Adduct Formation -- 1.2.3 Charge-Transfer Chemical Ionization -- 1.2.4 Reagent Gas -- 1.2.5 Negative Ion Formation -- 1.2.6 Desorption Chemical Ionization -- 1.3 Field Ionization -- 1.4 Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry -- 1.5 Field Desorption -- 1.6 Plasma Desorption -- 1.7 Laser Desorption -- 1.8 Matrix-Assisted Laser Desorption Ionization -- 1.8.1 Principle of MALDI -- 1.8.2 Practical Considerations -- 1.8.3 Fragmentations -- 1.8.4 Atmospheric Pressure Matrix-Assisted Laser Desorption Ionization -- 1.9 Thermospray -- 1.10 Atmospheric Pressure Ionization -- 1.11 Electrospray -- 1.11.1 Multiply Charged Ions -- 1.11.2 Electrochemistry and Electric Field as Origins of Multiply Charged Ions -- 1.11.3 Sensitivity to Concentration -- 1.11.4 Limitation of Ion Current from the Source by the Electrochemical Process -- 1.11.5 Practical Considerations -- 1.12 Atmospheric Pressure Chemical Ionization -- 1.13 Atmospheric Pressure Photoionization -- 1.14 Atmospheric Pressure Secondary Ion Mass Spectrometry -- 1.14.1 Desorption Electrospray Ionization -- 1.14.2 Direct Analysis in Real Time -- 1.15 Inorganic Ionization Sources -- 1.15.1 Thermal Ionization Source -- 1.15.2 Spark Source -- 1.15.3 Glow Discharge Source -- 1.15.4 Inductively Coupled Plasma Source -- 1.15.5 Practical Considerations -- 1.16 Gas-Phase Ion-Molecule Reactions -- 1.17 Formation and Fragmentation of Ions: Basic Rules -- 1.17.1 Electron Ionization and Photoionization Under Vacuum -- 1.17.2 Ionization at Low Pressure or at Atmospheric Pressure -- 1.17.3 Proton Transfer -- 1.17.4 Adduct Formation.
1.17.5 Formation of Aggregates or Clusters -- 1.17.6 Reactions at the Interface between Source and Analyser -- 2 Mass Analysers -- 2.1 Quadrupole Analysers -- 2.1.1 Description -- 2.1.2 Equations of Motion -- 2.1.3 Ion Guide and Collision Cell -- 2.1.4 Spectrometers with Several Quadrupoles in Tandem -- 2.2 Ion Trap Analysers -- 2.2.1 The 3D Ion Trap -- 2.2.2 The 2D Ion Trap -- 2.3 The Electrostatic Trap or 'Orbitrap' -- 2.4 Time-of-Flight Analysers -- 2.4.1 Linear Time-of-Flight Mass Spectrometer -- 2.4.2 Delayed Pulsed Extraction -- 2.4.3 Reflectrons -- 2.4.4 Tandem Mass Spectrometry with Time-of-Flight Analyser -- 2.4.5 Orthogonal Acceleration Time-of-Flight Instruments -- 2.5 Magnetic and Electromagnetic Analysers -- 2.5.1 Action of the Magnetic Field -- 2.5.2 Electrostatic Field -- 2.5.3 Dispersion and Resolution -- 2.5.4 Practical Considerations -- 2.5.5 Tandem Mass Spectrometry in Electromagnetic Analysers -- 2.6 Ion Cyclotron Resonance and Fourier Transform Mass Spectrometry -- 2.6.1 General Principle -- 2.6.2 Ion Cyclotron Resonance -- 2.6.3 Fourier Transform Mass Spectrometry -- 2.6.4 MS n in ICR/FTMS Instruments -- 2.7 Hybrid Instruments -- 2.7.1 Electromagnetic Analysers Coupled to Quadrupoles or Ion Trap -- 2.7.2 Ion Trap Analyser Combined with Time-of-Flight or Ion Cyclotron Resonance -- 2.7.3 Hybrids Including Time-of-Flight with Orthogonal Acceleration -- 3 Detectors and Computers -- 3.1 Detectors -- 3.1.1 Photographic Plate -- 3.1.2 Faraday Cup -- 3.1.3 Electron Multipliers -- 3.1.4 Electro-Optical Ion Detectors -- 3.2 Computers -- 3.2.1 Functions -- 3.2.2 Instrumentation -- 3.2.3 Data Acquisition -- 3.2.4 Data Conversion -- 3.2.5 Data Reduction -- 3.2.6 Library Search -- 4 Tandem Mass Spectrometry -- 4.1 Tandem Mass Spectrometry in Space or in Time -- 4.2 Tandem Mass Spectrometry Scan Modes.
4.3 Collision-Activated Decomposition or Collision-Induced Dissociation -- 4.3.1 Collision Energy Conversion to Internal Energy -- 4.3.2 High-Energy Collision (keV) -- 4.3.3 Low-Energy Collision (between 1 and 100 eV) -- 4.4 Other Methods of Ion Activation -- 4.5 Reactions Studied in MS/MS -- 4.6 Tandem Mass Spectrometry Applications -- 4.6.1 Structure Elucidation -- 4.6.2 Selective Detection of Target Compound Class -- 4.6.3 Ion-Molecule Reaction -- 4.6.4 The Kinetic Method -- 5 Mass Spectrometry/Chromatography Coupling -- 5.1 Elution Chromatography Coupling Techniques -- 5.1.1 Gas Chromatography/mass Spectrometry -- 5.1.2 Liquid Chromatography/mass Spectrometry -- 5.1.3 Capillary Electrophoresis/mass Spectrometry -- 5.2 Chromatography Data Acquisition Modes -- 5.3 Data Recording and Treatment -- 5.3.1 Data Recording -- 5.3.2 Instrument Control and Treatment of Results -- 6 Analytical Information -- 6.1 Mass Spectrometry Spectral Collections -- 6.2 High Resolution -- 6.2.1 Information at Different Resolving Powers -- 6.2.2 Determination of the Elemental Composition -- 6.3 Isotopic Abundances -- 6.4 Low-Mass Fragments and Lost Neutrals -- 6.5 Number of Rings or Unsaturations -- 6.6 Mass and Electron Parities, Closed-Shell Ions and Open-Shell Ions -- 6.6.1 Electron Parity -- 6.6.2 Mass Parity -- 6.6.3 Relationship between Mass and Electron Parity -- 6.7 Quantitative Data -- 6.7.1 Specificity -- 6.7.2 Sensitivity and Detection Limit -- 6.7.3 External Standard Method -- 6.7.4 Sources of Error -- 6.7.5 Internal Standard Method -- 6.7.6 Isotopic Dilution Method -- 7 Fragmentation Reactions -- 7.1 Electron Ionization and Fragmentation Rates -- 7.2 Quasi-Equilibrium and RRKM Theory -- 7.3 Ionization and Appearance Energies -- 7.4 Fragmentation Reactions of Positive Ions -- 7.4.1 Fragmentation of Odd-Electron Cations or Radical Cations.
7.4.2 Fragmentation of Cations with an Even Number of Electrons (EE ) -- 7.4.3 Fragmentations Obeying the Parity Rule -- 7.4.4 Fragmentations not Obeying the Parity Rule -- 7.5 Fragmentation Reactions of Negative Ions -- 7.5.1 Fragmentation Mechanisms of Even Electron Anions (EE - ) -- 7.5.2 Fragmentation Mechanisms of Radical Anions -- 7.6 Charge Remote Fragmentation -- 7.7 Spectrum Interpretation -- 7.7.1 Typical Ions -- 7.7.2 Presence of the Molecular Ion -- 7.7.3 Typical Neutrals -- 7.7.4 A Few Examples of the Interpretation of Mass Spectra -- 8 Analysis of Biomolecules -- 8.1 Biomolecules and Mass Spectrometry -- 8.2 Proteins and Peptides -- 8.2.1 ESI and MALDI -- 8.2.2 Structure and Sequence Determination Using Fragmentation -- 8.2.3 Applications -- 8.3 Oligonucleotides -- 8.3.1 Mass Spectra of Oligonucleotides -- 8.3.2 Applications of Mass Spectrometry to Oligonucleotides -- 8.3.3 Fragmentation of Oligonucleotides -- 8.3.4 Characterization of Modified Oligonucleotides -- 8.4 Oligosaccharides -- 8.4.1 Mass Spectra of Oligosaccharides -- 8.4.2 Fragmentation of Oligosaccharides -- 8.4.3 Degradation of Oligosaccharides Coupled with Mass Spectrometry -- 8.5 Lipids -- 8.5.1 Fatty Acids -- 8.5.2 Acylglycerols -- 8.5.3 Bile Acids -- 8.6 Metabolomics -- 8.6.1 Mass Spectrometry in Metabolomics -- 8.6.2 Applications -- 9 Exercises -- Questions -- Answers -- Appendices -- 1 Nomenclature -- 1.1 Units -- 1.2 Definitions -- 1.3 Analysers -- 1.4 Detection -- 1.5 Ionization -- 1.6 Ion Types -- 1.7 Ion-Molecule Reaction -- 1.8 Fragmentation -- 2 Acronyms and Abbreviations -- 3 Fundamental Physical Constants -- 4A Table of Isotopes in Ascending Mass Order -- 4B Table of Isotopes in Alphabetical Order -- 5 Isotopic Abundances (in %) for Various Elemental Compositions CHON -- 6 Gas-Phase Ion Thermochemical Data of Molecules.
7 Gas-Phase Ion Thermochemical Data of Radicals -- 8 Literature on Mass Spectrometry -- 9 Mass Spectrometry on Internet -- Index.
Record Nr. UNINA-9910795826403321
de Hoffmann Edmond  
Newy York : , : John Wiley & Sons, Incorporated, , 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mass Spectrometry : Principles and Applications
Mass Spectrometry : Principles and Applications
Autore de Hoffmann Edmond
Edizione [3rd ed.]
Pubbl/distr/stampa Newy York : , : John Wiley & Sons, Incorporated, , 2007
Descrizione fisica 1 online resource (503 pages)
Disciplina 543/.0873
Altri autori (Persone) StroobantVincent
De HoffmannEdmond
Soggetto topico Mass spectrometry
Soggetto genere / forma Electronic books.
ISBN 9780470512135
9780470033104
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Mass Spectrometry -- Contents -- Preface -- Introduction -- Principles -- Diagram of a Mass Spectrometer -- History -- Ion Free Path -- 1 Ion Sources -- 1.1 Electron Ionization -- 1.2 Chemical Ionization -- 1.2.1 Proton Transfer -- 1.2.2 Adduct Formation -- 1.2.3 Charge-Transfer Chemical Ionization -- 1.2.4 Reagent Gas -- 1.2.5 Negative Ion Formation -- 1.2.6 Desorption Chemical Ionization -- 1.3 Field Ionization -- 1.4 Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry -- 1.5 Field Desorption -- 1.6 Plasma Desorption -- 1.7 Laser Desorption -- 1.8 Matrix-Assisted Laser Desorption Ionization -- 1.8.1 Principle of MALDI -- 1.8.2 Practical Considerations -- 1.8.3 Fragmentations -- 1.8.4 Atmospheric Pressure Matrix-Assisted Laser Desorption Ionization -- 1.9 Thermospray -- 1.10 Atmospheric Pressure Ionization -- 1.11 Electrospray -- 1.11.1 Multiply Charged Ions -- 1.11.2 Electrochemistry and Electric Field as Origins of Multiply Charged Ions -- 1.11.3 Sensitivity to Concentration -- 1.11.4 Limitation of Ion Current from the Source by the Electrochemical Process -- 1.11.5 Practical Considerations -- 1.12 Atmospheric Pressure Chemical Ionization -- 1.13 Atmospheric Pressure Photoionization -- 1.14 Atmospheric Pressure Secondary Ion Mass Spectrometry -- 1.14.1 Desorption Electrospray Ionization -- 1.14.2 Direct Analysis in Real Time -- 1.15 Inorganic Ionization Sources -- 1.15.1 Thermal Ionization Source -- 1.15.2 Spark Source -- 1.15.3 Glow Discharge Source -- 1.15.4 Inductively Coupled Plasma Source -- 1.15.5 Practical Considerations -- 1.16 Gas-Phase Ion-Molecule Reactions -- 1.17 Formation and Fragmentation of Ions: Basic Rules -- 1.17.1 Electron Ionization and Photoionization Under Vacuum -- 1.17.2 Ionization at Low Pressure or at Atmospheric Pressure -- 1.17.3 Proton Transfer -- 1.17.4 Adduct Formation.
1.17.5 Formation of Aggregates or Clusters -- 1.17.6 Reactions at the Interface between Source and Analyser -- 2 Mass Analysers -- 2.1 Quadrupole Analysers -- 2.1.1 Description -- 2.1.2 Equations of Motion -- 2.1.3 Ion Guide and Collision Cell -- 2.1.4 Spectrometers with Several Quadrupoles in Tandem -- 2.2 Ion Trap Analysers -- 2.2.1 The 3D Ion Trap -- 2.2.2 The 2D Ion Trap -- 2.3 The Electrostatic Trap or 'Orbitrap' -- 2.4 Time-of-Flight Analysers -- 2.4.1 Linear Time-of-Flight Mass Spectrometer -- 2.4.2 Delayed Pulsed Extraction -- 2.4.3 Reflectrons -- 2.4.4 Tandem Mass Spectrometry with Time-of-Flight Analyser -- 2.4.5 Orthogonal Acceleration Time-of-Flight Instruments -- 2.5 Magnetic and Electromagnetic Analysers -- 2.5.1 Action of the Magnetic Field -- 2.5.2 Electrostatic Field -- 2.5.3 Dispersion and Resolution -- 2.5.4 Practical Considerations -- 2.5.5 Tandem Mass Spectrometry in Electromagnetic Analysers -- 2.6 Ion Cyclotron Resonance and Fourier Transform Mass Spectrometry -- 2.6.1 General Principle -- 2.6.2 Ion Cyclotron Resonance -- 2.6.3 Fourier Transform Mass Spectrometry -- 2.6.4 MS n in ICR/FTMS Instruments -- 2.7 Hybrid Instruments -- 2.7.1 Electromagnetic Analysers Coupled to Quadrupoles or Ion Trap -- 2.7.2 Ion Trap Analyser Combined with Time-of-Flight or Ion Cyclotron Resonance -- 2.7.3 Hybrids Including Time-of-Flight with Orthogonal Acceleration -- 3 Detectors and Computers -- 3.1 Detectors -- 3.1.1 Photographic Plate -- 3.1.2 Faraday Cup -- 3.1.3 Electron Multipliers -- 3.1.4 Electro-Optical Ion Detectors -- 3.2 Computers -- 3.2.1 Functions -- 3.2.2 Instrumentation -- 3.2.3 Data Acquisition -- 3.2.4 Data Conversion -- 3.2.5 Data Reduction -- 3.2.6 Library Search -- 4 Tandem Mass Spectrometry -- 4.1 Tandem Mass Spectrometry in Space or in Time -- 4.2 Tandem Mass Spectrometry Scan Modes.
4.3 Collision-Activated Decomposition or Collision-Induced Dissociation -- 4.3.1 Collision Energy Conversion to Internal Energy -- 4.3.2 High-Energy Collision (keV) -- 4.3.3 Low-Energy Collision (between 1 and 100 eV) -- 4.4 Other Methods of Ion Activation -- 4.5 Reactions Studied in MS/MS -- 4.6 Tandem Mass Spectrometry Applications -- 4.6.1 Structure Elucidation -- 4.6.2 Selective Detection of Target Compound Class -- 4.6.3 Ion-Molecule Reaction -- 4.6.4 The Kinetic Method -- 5 Mass Spectrometry/Chromatography Coupling -- 5.1 Elution Chromatography Coupling Techniques -- 5.1.1 Gas Chromatography/mass Spectrometry -- 5.1.2 Liquid Chromatography/mass Spectrometry -- 5.1.3 Capillary Electrophoresis/mass Spectrometry -- 5.2 Chromatography Data Acquisition Modes -- 5.3 Data Recording and Treatment -- 5.3.1 Data Recording -- 5.3.2 Instrument Control and Treatment of Results -- 6 Analytical Information -- 6.1 Mass Spectrometry Spectral Collections -- 6.2 High Resolution -- 6.2.1 Information at Different Resolving Powers -- 6.2.2 Determination of the Elemental Composition -- 6.3 Isotopic Abundances -- 6.4 Low-Mass Fragments and Lost Neutrals -- 6.5 Number of Rings or Unsaturations -- 6.6 Mass and Electron Parities, Closed-Shell Ions and Open-Shell Ions -- 6.6.1 Electron Parity -- 6.6.2 Mass Parity -- 6.6.3 Relationship between Mass and Electron Parity -- 6.7 Quantitative Data -- 6.7.1 Specificity -- 6.7.2 Sensitivity and Detection Limit -- 6.7.3 External Standard Method -- 6.7.4 Sources of Error -- 6.7.5 Internal Standard Method -- 6.7.6 Isotopic Dilution Method -- 7 Fragmentation Reactions -- 7.1 Electron Ionization and Fragmentation Rates -- 7.2 Quasi-Equilibrium and RRKM Theory -- 7.3 Ionization and Appearance Energies -- 7.4 Fragmentation Reactions of Positive Ions -- 7.4.1 Fragmentation of Odd-Electron Cations or Radical Cations.
7.4.2 Fragmentation of Cations with an Even Number of Electrons (EE ) -- 7.4.3 Fragmentations Obeying the Parity Rule -- 7.4.4 Fragmentations not Obeying the Parity Rule -- 7.5 Fragmentation Reactions of Negative Ions -- 7.5.1 Fragmentation Mechanisms of Even Electron Anions (EE - ) -- 7.5.2 Fragmentation Mechanisms of Radical Anions -- 7.6 Charge Remote Fragmentation -- 7.7 Spectrum Interpretation -- 7.7.1 Typical Ions -- 7.7.2 Presence of the Molecular Ion -- 7.7.3 Typical Neutrals -- 7.7.4 A Few Examples of the Interpretation of Mass Spectra -- 8 Analysis of Biomolecules -- 8.1 Biomolecules and Mass Spectrometry -- 8.2 Proteins and Peptides -- 8.2.1 ESI and MALDI -- 8.2.2 Structure and Sequence Determination Using Fragmentation -- 8.2.3 Applications -- 8.3 Oligonucleotides -- 8.3.1 Mass Spectra of Oligonucleotides -- 8.3.2 Applications of Mass Spectrometry to Oligonucleotides -- 8.3.3 Fragmentation of Oligonucleotides -- 8.3.4 Characterization of Modified Oligonucleotides -- 8.4 Oligosaccharides -- 8.4.1 Mass Spectra of Oligosaccharides -- 8.4.2 Fragmentation of Oligosaccharides -- 8.4.3 Degradation of Oligosaccharides Coupled with Mass Spectrometry -- 8.5 Lipids -- 8.5.1 Fatty Acids -- 8.5.2 Acylglycerols -- 8.5.3 Bile Acids -- 8.6 Metabolomics -- 8.6.1 Mass Spectrometry in Metabolomics -- 8.6.2 Applications -- 9 Exercises -- Questions -- Answers -- Appendices -- 1 Nomenclature -- 1.1 Units -- 1.2 Definitions -- 1.3 Analysers -- 1.4 Detection -- 1.5 Ionization -- 1.6 Ion Types -- 1.7 Ion-Molecule Reaction -- 1.8 Fragmentation -- 2 Acronyms and Abbreviations -- 3 Fundamental Physical Constants -- 4A Table of Isotopes in Ascending Mass Order -- 4B Table of Isotopes in Alphabetical Order -- 5 Isotopic Abundances (in %) for Various Elemental Compositions CHON -- 6 Gas-Phase Ion Thermochemical Data of Molecules.
7 Gas-Phase Ion Thermochemical Data of Radicals -- 8 Literature on Mass Spectrometry -- 9 Mass Spectrometry on Internet -- Index.
Record Nr. UNINA-9910823092403321
de Hoffmann Edmond  
Newy York : , : John Wiley & Sons, Incorporated, , 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Understanding mass spectra [[electronic resource] ] : a basic approach / / R. Martin Smith
Understanding mass spectra [[electronic resource] ] : a basic approach / / R. Martin Smith
Autore Smith R. Martin
Edizione [2nd ed.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley Interscience, c2004
Descrizione fisica 1 online resource (394 p.)
Disciplina 543
543.0873
543/.0873
Soggetto topico Mass spectrometry
ISBN 1-280-26487-X
9786610264872
0-470-25207-3
0-471-47934-9
0-471-47935-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto UNDERSTANDING MASS SPECTRA Second Edition; CONTENTS; Preface to the Second Edition; Acknowledgments; Abbreviations and Notations Used in This Book; 1 Instrumentation; 1.1. Introduction; 1.1.1. Overview; 1.1.2. Sample Introduction; 1.2. Ionization Source; 1.2.1. Electron Ionization Source; 1.2.2. Chemical Ionization; 1.2.3. Other Ionization Methods; 1.2.3.1. Electrospray Ionization; 1.2.3.2. Desorption Ionization; 1.3. m/z Analysis; 1.3.1. Time-of-Flight (TOF); 1.3.2. Magnetic Sector; 1.3.3. Transmission Quadrupole; 1.3.3.1. Selected Ion Monitoring (SIM); 1.3.4. Quadrupole Ion Trap (QIT)
1.3.5. Other Types of Mass Analysis1.3.5.1. Mass Spectrometry/Mass Spectrometry(MS/MS); 1.3.5.2. Accurate m/z Analysis; 1.3.6. Spectral Skewing; 1.4. Ion Detection; 1.4.1. Electron Multiplier; 1.4.2. Photomultiplier Detector; 1.5. Data System; 1.5.1. Instrument Tuning and Calibration; 1.5.2. The Mass Spectrum; 1.5.2.1. Production of the Mass Spectrum; 1.5.2.2. Terminology: Ions vs. Peaks; 1.5.3. Library Searches; 1.5.4. Using the Data System to Analyze GC/MS Data; 1.6. Criteria for Good-Quality Spectra; Additional Problems; Mass Spectrometric Resources on the Internet
References and Suggested Reading2 Elemental Composition from Peak Intensities; 2.1. Natural Isotopic Abundances; 2.1.1. Atomic and Molecular Mass; 2.1.2. Calculated Exact Masses and Mass Defects; 2.2. Determining Elemental Composition from Isotope Peak Intensities; 2.2.1. One or More Atoms of a Single Element; 2.2.1.1. Chlorine and Bromine; 2.2.1.2. Ion Designation and Nomenclature; 2.2.1.3. Probability Considerations with Multiple Numbers of Atoms; 2.2.1.4. Isotope Peak Intensity Ratios for Carbon-Containing Ions-The X + 1 Peak; 2.2.1.5. A, A + 1, and A + 2 Elements
2.2.1.6 Isotope Peak Intensity Ratios for Carbon-Containing Ions-The X + 2 Peak2.2.1.7. Overlapping Peak Clusters-Contributions from (13)C Only; 2.2.1.8. Silicon; 2.2.2. Complex Isotope Clusters; 2.2.2.1. Sulfur Dioxide; 2.2.2.2. Diazepam; 2.3. Obtaining Elemental Compositions from Isotope Peak Intensities; Examples; Additional Problems; References; 3 Ionization, Fragmentation, and Electron Accounting; 3.1. A Brief Review of Orbitals and Bonding; 3.2. Even- and Odd-Electron Species; 3.3. Site of Initial Ionization; 3.4. Types of Fragmentation; 3.5. The Nitrogen Rule
3.6. Energy Considerations in Fragmentation Processes3.6.1. Fragmentation Rates; 3.6.2. Metastable Ions; 3.6.3. Energy Diagrams; 3.6.4. Stevenson's Rule; Additional Examples; Problems; References; 4 Neutral Losses and Ion Series; 4.1. Neutral Losses; 4.1.1. Losses from the Molecular Ion; 4.1.2. Loss of Small Molecules from Aromatic Ions; 4.2. Low-Mass Ion Series; 4.2.1. n-Alkane Spectra; 4.2.2. Effect of Chain Branching on the Spectra of Aliphatic Hydrocarbons; 4.2.3. Ion Series for Nonaromatic Compounds; 4.2.4. Aromatic Ion Series; 4.2.5. Use of Ion Series: Mass Chromatograms
Additional Problems
Record Nr. UNINA-9910146065903321
Smith R. Martin  
Hoboken, N.J., : Wiley Interscience, c2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Understanding mass spectra [[electronic resource] ] : a basic approach / / R. Martin Smith
Understanding mass spectra [[electronic resource] ] : a basic approach / / R. Martin Smith
Autore Smith R. Martin
Edizione [2nd ed.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley Interscience, c2004
Descrizione fisica 1 online resource (394 p.)
Disciplina 543
543.0873
543/.0873
Soggetto topico Mass spectrometry
ISBN 1-280-26487-X
9786610264872
0-470-25207-3
0-471-47934-9
0-471-47935-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto UNDERSTANDING MASS SPECTRA Second Edition; CONTENTS; Preface to the Second Edition; Acknowledgments; Abbreviations and Notations Used in This Book; 1 Instrumentation; 1.1. Introduction; 1.1.1. Overview; 1.1.2. Sample Introduction; 1.2. Ionization Source; 1.2.1. Electron Ionization Source; 1.2.2. Chemical Ionization; 1.2.3. Other Ionization Methods; 1.2.3.1. Electrospray Ionization; 1.2.3.2. Desorption Ionization; 1.3. m/z Analysis; 1.3.1. Time-of-Flight (TOF); 1.3.2. Magnetic Sector; 1.3.3. Transmission Quadrupole; 1.3.3.1. Selected Ion Monitoring (SIM); 1.3.4. Quadrupole Ion Trap (QIT)
1.3.5. Other Types of Mass Analysis1.3.5.1. Mass Spectrometry/Mass Spectrometry(MS/MS); 1.3.5.2. Accurate m/z Analysis; 1.3.6. Spectral Skewing; 1.4. Ion Detection; 1.4.1. Electron Multiplier; 1.4.2. Photomultiplier Detector; 1.5. Data System; 1.5.1. Instrument Tuning and Calibration; 1.5.2. The Mass Spectrum; 1.5.2.1. Production of the Mass Spectrum; 1.5.2.2. Terminology: Ions vs. Peaks; 1.5.3. Library Searches; 1.5.4. Using the Data System to Analyze GC/MS Data; 1.6. Criteria for Good-Quality Spectra; Additional Problems; Mass Spectrometric Resources on the Internet
References and Suggested Reading2 Elemental Composition from Peak Intensities; 2.1. Natural Isotopic Abundances; 2.1.1. Atomic and Molecular Mass; 2.1.2. Calculated Exact Masses and Mass Defects; 2.2. Determining Elemental Composition from Isotope Peak Intensities; 2.2.1. One or More Atoms of a Single Element; 2.2.1.1. Chlorine and Bromine; 2.2.1.2. Ion Designation and Nomenclature; 2.2.1.3. Probability Considerations with Multiple Numbers of Atoms; 2.2.1.4. Isotope Peak Intensity Ratios for Carbon-Containing Ions-The X + 1 Peak; 2.2.1.5. A, A + 1, and A + 2 Elements
2.2.1.6 Isotope Peak Intensity Ratios for Carbon-Containing Ions-The X + 2 Peak2.2.1.7. Overlapping Peak Clusters-Contributions from (13)C Only; 2.2.1.8. Silicon; 2.2.2. Complex Isotope Clusters; 2.2.2.1. Sulfur Dioxide; 2.2.2.2. Diazepam; 2.3. Obtaining Elemental Compositions from Isotope Peak Intensities; Examples; Additional Problems; References; 3 Ionization, Fragmentation, and Electron Accounting; 3.1. A Brief Review of Orbitals and Bonding; 3.2. Even- and Odd-Electron Species; 3.3. Site of Initial Ionization; 3.4. Types of Fragmentation; 3.5. The Nitrogen Rule
3.6. Energy Considerations in Fragmentation Processes3.6.1. Fragmentation Rates; 3.6.2. Metastable Ions; 3.6.3. Energy Diagrams; 3.6.4. Stevenson's Rule; Additional Examples; Problems; References; 4 Neutral Losses and Ion Series; 4.1. Neutral Losses; 4.1.1. Losses from the Molecular Ion; 4.1.2. Loss of Small Molecules from Aromatic Ions; 4.2. Low-Mass Ion Series; 4.2.1. n-Alkane Spectra; 4.2.2. Effect of Chain Branching on the Spectra of Aliphatic Hydrocarbons; 4.2.3. Ion Series for Nonaromatic Compounds; 4.2.4. Aromatic Ion Series; 4.2.5. Use of Ion Series: Mass Chromatograms
Additional Problems
Record Nr. UNINA-9910830551103321
Smith R. Martin  
Hoboken, N.J., : Wiley Interscience, c2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Understanding mass spectra [[electronic resource] ] : a basic approach / / R. Martin Smith
Understanding mass spectra [[electronic resource] ] : a basic approach / / R. Martin Smith
Autore Smith R. Martin
Edizione [2nd ed.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley Interscience, c2004
Descrizione fisica 1 online resource (394 p.)
Disciplina 543
543.0873
543/.0873
Soggetto topico Mass spectrometry
ISBN 1-280-26487-X
9786610264872
0-470-25207-3
0-471-47934-9
0-471-47935-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto UNDERSTANDING MASS SPECTRA Second Edition; CONTENTS; Preface to the Second Edition; Acknowledgments; Abbreviations and Notations Used in This Book; 1 Instrumentation; 1.1. Introduction; 1.1.1. Overview; 1.1.2. Sample Introduction; 1.2. Ionization Source; 1.2.1. Electron Ionization Source; 1.2.2. Chemical Ionization; 1.2.3. Other Ionization Methods; 1.2.3.1. Electrospray Ionization; 1.2.3.2. Desorption Ionization; 1.3. m/z Analysis; 1.3.1. Time-of-Flight (TOF); 1.3.2. Magnetic Sector; 1.3.3. Transmission Quadrupole; 1.3.3.1. Selected Ion Monitoring (SIM); 1.3.4. Quadrupole Ion Trap (QIT)
1.3.5. Other Types of Mass Analysis1.3.5.1. Mass Spectrometry/Mass Spectrometry(MS/MS); 1.3.5.2. Accurate m/z Analysis; 1.3.6. Spectral Skewing; 1.4. Ion Detection; 1.4.1. Electron Multiplier; 1.4.2. Photomultiplier Detector; 1.5. Data System; 1.5.1. Instrument Tuning and Calibration; 1.5.2. The Mass Spectrum; 1.5.2.1. Production of the Mass Spectrum; 1.5.2.2. Terminology: Ions vs. Peaks; 1.5.3. Library Searches; 1.5.4. Using the Data System to Analyze GC/MS Data; 1.6. Criteria for Good-Quality Spectra; Additional Problems; Mass Spectrometric Resources on the Internet
References and Suggested Reading2 Elemental Composition from Peak Intensities; 2.1. Natural Isotopic Abundances; 2.1.1. Atomic and Molecular Mass; 2.1.2. Calculated Exact Masses and Mass Defects; 2.2. Determining Elemental Composition from Isotope Peak Intensities; 2.2.1. One or More Atoms of a Single Element; 2.2.1.1. Chlorine and Bromine; 2.2.1.2. Ion Designation and Nomenclature; 2.2.1.3. Probability Considerations with Multiple Numbers of Atoms; 2.2.1.4. Isotope Peak Intensity Ratios for Carbon-Containing Ions-The X + 1 Peak; 2.2.1.5. A, A + 1, and A + 2 Elements
2.2.1.6 Isotope Peak Intensity Ratios for Carbon-Containing Ions-The X + 2 Peak2.2.1.7. Overlapping Peak Clusters-Contributions from (13)C Only; 2.2.1.8. Silicon; 2.2.2. Complex Isotope Clusters; 2.2.2.1. Sulfur Dioxide; 2.2.2.2. Diazepam; 2.3. Obtaining Elemental Compositions from Isotope Peak Intensities; Examples; Additional Problems; References; 3 Ionization, Fragmentation, and Electron Accounting; 3.1. A Brief Review of Orbitals and Bonding; 3.2. Even- and Odd-Electron Species; 3.3. Site of Initial Ionization; 3.4. Types of Fragmentation; 3.5. The Nitrogen Rule
3.6. Energy Considerations in Fragmentation Processes3.6.1. Fragmentation Rates; 3.6.2. Metastable Ions; 3.6.3. Energy Diagrams; 3.6.4. Stevenson's Rule; Additional Examples; Problems; References; 4 Neutral Losses and Ion Series; 4.1. Neutral Losses; 4.1.1. Losses from the Molecular Ion; 4.1.2. Loss of Small Molecules from Aromatic Ions; 4.2. Low-Mass Ion Series; 4.2.1. n-Alkane Spectra; 4.2.2. Effect of Chain Branching on the Spectra of Aliphatic Hydrocarbons; 4.2.3. Ion Series for Nonaromatic Compounds; 4.2.4. Aromatic Ion Series; 4.2.5. Use of Ion Series: Mass Chromatograms
Additional Problems
Record Nr. UNINA-9910841065503321
Smith R. Martin  
Hoboken, N.J., : Wiley Interscience, c2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui