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Chemical alternatives assessments / / [edited by R.E. Hester and R.M. Harrison]
| Chemical alternatives assessments / / [edited by R.E. Hester and R.M. Harrison] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cambridge, : Royal Society of Chemistry, 2013 |
| Descrizione fisica | 1 online resource (323 p.) |
| Disciplina | 363.1763 |
| Altri autori (Persone) |
HesterR. E (Ronald E.)
HarrisonR. M |
| Collana |
ISSN
Issues in environmental science and technology |
| Soggetto topico |
Chemistry, Analytic - Industrial applications
Chemicals - Physiological effect - Testing Hazardous substances - Risk assessment Substitute products |
| ISBN | 1-84973-723-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Contents -- Editors -- List of Contributors -- Chemicals Alternatives Assessment (CAA): Tools for Selecting Less Hazardous Chemicals -- 1.1 Introduction to Chemicals Alternatives Assessments -- 1.2 Common Traits Among CAA Paradigms -- 1.2.1 Step One: Hazard Assessment Through Literature Search and Data Identification -- 1.2.2 Step Two: Hazard Classification and Benchmarking of Relevant Data -- 1.2.3 Step Three: CAA Report Preparation -- 1.3 Life-cycle Assessment and Chemicals Alternatives Assessment -- 1.4 Chemical Alternatives Assessment Paradigms in Use: a Critical Evaluation -- 1.4.1 US EPA's Design for the Environment (DfE) -- 1.4.2 CPA's GreenScreen™ -- 1.4.3 Cradle to Cradle® (C2C) -- 1.4.4 TURI's Pollution Prevention Options Analysis System (P2OASys) -- 1.4.5 The Chemical Scoring and Ranking Assessment Model (SCRAM) -- 1.4.6 Chemicals Assessment and Ranking System (CARS) -- 1.4.7 SC Johnson & -- Son's Greenlist™ -- 1.4.8 PRIO -- 1.4.9 The Quick Scan -- 1.4.10 The Column Model and GHS Column Model -- 1.4.11 Evaluation Matrix -- 1.5 Challenges Facing Chemicals Alternatives Assessment Methods -- 1.5.1 Chemicals Alternatives Assessments and Data Gaps -- 1.6 Conclusion -- References -- European Initiatives for Selecting Sustainable Flame Retardants -- 2.1 Introduction - What are Flame Retardants? -- 2.1.1 Bromine and Chlorine -- 2.1.3 Nitrogen -- 2.1.4 Mineral Flame Retardants -- 2.1.5 Other Flame Retardants and Synergists: Borates, Zinc Compounds and Expandable Graphite -- 2.2 Environmental and Human Health Concerns About Halogenated Fire Retardants -- 2.3 European Activities Related to Non-halogenated Flame Retardants -- 2.3.1 Formation of the Phosphorus, Inorganic and Nitrogen Flame Retardants Association (pinfa) -- 2.3.2 Technology Drivers: Electronics Groups iNEMI and HDPUG -- 2.3.3 European Legislation: RoHS and REACH.
2.3.4 GreenScreen™ -- 2.3.5 ENFIRO -- 2.3.6 Ecolabels -- 2.4 Conclusion -- References -- MBDC Cradle to Cradle® Product Evaluation and Certification Program -- 3.1 Introduction -- 3.1.1 What is Cradle to Cradle® Design? -- 3.1.2 Long-term Goals - Short-term Actions and Transitions -- 3.1.3 The Cradle to Cradle Principles -- 3.1.4 Complementary Metabolisms -- 3.2 Product Certification Program Overview -- 3.2.1 Certification Levels -- 3.2.2 Program Categories -- 3.2.3 The Cradle to Cradle CertifiedCM Marks -- 3.3 Product Certification Overview -- 3.3.1 Scope -- 3.3.2 Continuous Improvement and Optimization -- 3.3.3 Material Health -- 3.3.4 Material Reutilization -- 3.3.5 Renewable Energy and Carbon Management -- 3.3.6 Water Stewardship -- 3.3.7 Social Fairness -- 3.3.8 Certification Program Summary -- Notes and References -- China's Implementation of Alternatives Assessment in the Building Industry: GIGA -- 4.1 Introduction -- 4.2 China Context -- 4.2.1 Health -- 4.2.2 Barriers to Health -- 4.3 Resurgence of Health -- 4.3.1 Trust as a Catalyst -- 4.3.2 Wealth as a Catalyst -- 4.3.3 Access to Information as a Catalyst -- 4.4 Social Media and the Rebuilding of Trust -- 4.4.1 Perfect Storm of Change -- 4.5 Minimization Versus Regeneration in China -- 4.5.1 Regenerative Chemistry -- 4.6 GIGA (Green Ideas, Green Actions) -- 4.6.1 GIGA: the User's Perspective -- 4.6.2 GIGA: Green Algorithm -- 4.6.3 GIGA: Unpacking Alternatives Assessment -- 4.7 Impact: Process -- 4.8 Alternatives Assessment at Scale -- 4.9 Conclusion -- References -- A Collaborative Industry and University Alternative Assessment of Plasticizers for Wire and Cable -- 5.1 Background -- 5.2 Project Workplan -- 5.3 Selection of a Chemical/Chemical Class of Concern and Application -- 5.4 Pilot Project Team Formation -- 5.5 Screening Against the Red List. 5.6 Using the Quick Chemical Assessment Tool (QCAT) to Screen Chemicals -- 5.7 Applying the GreenScreen™ -- 5.8 Conducting the Chemical Hazard Assessment Portion of the GC3 Project -- 5.8.1 Obtaining Data for GreenScreens™ -- 5.8.2 Reviewing Draft GreenScreens™ -- 5.9 Results -- 5.9.1 Results of the GreenScreen™ Assessments of Alternative Plasticizers -- 5.9.2 Technical and Cost Evaluation of Plasticizers -- 5.9.3 Lessons Learned in the Project -- 5.10 Conclusion -- Acknowledgements -- References -- Chemical Hazard Assessment and the GreenScreen™ for Safer Chemicals -- 6.1 Introduction -- 6.1.1 Origins of the GreenScreen™ for Safer Chemicals -- 6.2 How it Works -- 6.2.1 Assess and Classify Hazards -- 6.2.2 Apply the Benchmarks -- 6.2.3 Make Informed Decisions and Drive Innovation -- 6.3 Continual Improvement -- 6.3.1 Advances to the GreenScreen™ Method -- 6.3.2 Developing Infrastructure for the GreenScreen™ Program -- 6.4 Conclusion -- Acknowledgement -- References -- Hewlett-Packard's Use of the GreenScreen™ for Safer Chemicals -- 7.1 Introduction -- 7.2 Tools and Methods -- 7.2.1 Restricted Substance List (RSL) Screening -- 7.2.2 Risk Phrase or Hazard Statement Screening -- 7.2.3 Multi-criteria Decision Analyses -- 7.2.4 Life-cycle Analysis (LCA) -- 7.2.5 Risk Assessment -- 7.2.6 Scoring Schemes, Including the GreenScreen for Safer Chemicals -- 7.3 Integrated Alternatives Assessment Protocol -- 7.3.1 Step 1 - Identify Substances of Concern -- 7.3.2 Step 2 - Characterize Function and End Uses of the Substance -- 7.3.3 Step 3 - Identify Potential Alternatives -- 7.3.4 Step 4 - Assess Chemical Hazards -- 7.3.5 Step 5 - Evaluate Technical and Economic Performance -- 7.3.6 Step 6 - Apply Life-cycle Thinking -- 7.3.7 Step 7 - Approve Alternatives -- 7.4 Opportunities for Improvement -- 7.4.1 Methods -- 7.4.2 Infrastructure. 7.4.3 Criteria for Preferred Material in Ecolabels -- 7.5 Conclusion -- References -- DSM's Sustainability Journey Towards a Proactive Ingredient Policy for Gaining Effectiveness in the Design of Better Products -- 8.1 General Introduction: Sustainability as Business Growth Driver Opportunity and Global Trends -- 8.1.1 Ecological Benefits: Transparent Assessment with Life-cycle Assessment (LCA) -- 8.1.2 Importance of Global Platforms and Partnerships -- 8.1.3 The Challenges Ahead for a Life Sciences and Materials Sciences Company -- 8.2 A Brighter Future with Composites -- 8.2.1 Leading-edge Performance -- 8.2.2 Lower Eco-footprint -- 8.2.3 Elimination of Substances of hazardous concern -- 8.2.4 BluCure™ Cobalt-free Curing Systems -- 8.2.5 Alternatives to Styrene Reactive Diluents -- 8.2.6 Introduction of Good Manufacturing Practice (GMP) -- 8.3 Facing the Technical, Performance and Cost Challenges: the Introduction of Halogen-free Flame Retardants -- 8.3.1 Overcoming Technical Challenges -- 8.3.2 Moving Forward -- 8.4 Conclusion -- References -- US Environmental Protection Agency's Design for the Environment (DfE) Alternatives Assessment Program -- 9.1 Introduction -- 9.2 Selecting an Approach for Chemical Substitution -- 9.3 PentaBDE Case Study -- 9.3.1 How DfE Conducted CAA for PentaBDE -- 9.3.2 Limitations of Original Methodology and Criteria -- 9.4 New CAA Methodology and Criteria: Steps to Conducting a CAA -- 9.4.1 Step 1: Determine Feasibility -- 9.4.2 Step 2: Collect Information on Chemical Alternatives -- 9.4.3 Step 3: Convene Stakeholders -- 9.4.4 Step 4: Identify Alternatives -- 9.4.5 Step 5: Conduct the Hazard Assessment -- 9.4.6 Step 6: Apply Economic and Life-cycle Context -- 9.4.7 Step 7: Apply the Results in Decision-making for Safer Chemical Substitutes -- 9.5 Application of New CAA Criteria. 9.5.1 BPA Alternatives in Thermal Paper Partnership -- 9.5.2 Flame Retardant Alternatives to DecaBDE Partnership -- 9.6 Safer Product Labeling Program Case Study -- 9.6.1 Functional Use Concept Advances Greener Chemistry -- 9.6.2 Ingredient-class Criteria Define 'Safer' Chemicals -- 9.6.3 Partnership Process Fosters Teamwork in Safer Formulation -- 9.6.4 Development of Safer Alternatives -- 9.7 What's Next -- 9.7.1 The Community of Practice is Growing -- 9.7.2 Promoting Harmony in CAAs -- References -- NGO Initiatives in the EU - Identifying Substances of Very High Concern (SVHCs) and Driving Safer Chemical Substitutes in Response to REACH -- 10.1 ChemSec Background -- 10.2 Overview of NGO Initiatives - Putting REACH into Practice and Working with Companies -- 10.2.1 The SIN List -- 10.2.2 Substitution Support Portal - SUBSPORT -- 10.2.3 Transparency -- 10.2.4 Business Initiatives -- 10.2.5 NGO-Business Cooperation - Electronics -- 10.2.6 Engaging Financial Investors -- 10.3 The SIN List in Focus -- 10.3.1 REACH and Substances of Very High Concern -- 10.3.2 General Principles Used for the Compilation of the SIN List -- 10.3.3 How the SIN List Has Been Used and Received -- 10.3.4 Detailed Methodology -- 10.3.5 The First Assessment Process (SIN List 1.0) -- 10.3.6 The Second Assessment Process (SIN List 2.0) -- 10.4 Finding Safer Alternatives Through SUBSPORT -- 10.4.1 Background -- 10.4.2 The Web Portal -- 10.4.3 The Substitution Case Story Database -- 10.5 Conclusion -- References -- Alternatives Assessment in Regulatory Policy: History and Future Directions -- 11.1 Introduction -- 11.2 Rationale for Informed Substitution -- 11.3 Evolution of Alternatives Assessment Elements in Government Chemicals Reduction Policies -- 11.3.1 Chemical Restriction and Phase-out Policy Development -- 11.3.2 Alternatives Assessment Policy Development. 11.3.3 Convergence of Chemical Restriction and Alternatives Assessment Policies. |
| Record Nr. | UNINA-9910132706203321 |
| Cambridge, : Royal Society of Chemistry, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Reviews of Environmental Contamination and Toxicology / / edited by David M. Whitacre
| Reviews of Environmental Contamination and Toxicology / / edited by David M. Whitacre |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (152 p.) |
| Disciplina | 363.1763 |
| Collana | Reviews of Environmental Contamination and Toxicology, Continuation of Residue Reviews |
| Soggetto topico |
Ecotoxicology
Environmental management Waste management Environmental Management Waste Management/Waste Technology |
| ISBN | 3-319-03777-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Mercury toxicity and neurodegenerative effects / Alessia Carocci, Nicola Rovito, Maria Stefania Sinicropi, Giuseppe Genchi -- E-waste disposal effects on the aquatic environment: Accra, Ghana / Jingyu Huang, Philip Nti Nkrumah, Desmond Ofosu Anim, Ebenezer Mensah -- Environmental fate and toxicology of clomazone / April Van Scoy and Ronald S. Tjeerdema -- Modulation of plant growth and metabolism in cadmium-enriched environments / Shaista Qadir, Sumiya Jamshieed, Saiema Rasool, Muhammad Ashraf, Nudrat Aisha Akram and Parvaiz Ahmad -- Effect of fruit and vegetable processing on reduction of synthetic pyrethroid residues / Reena Chauhan, Beena Kumari and M.K. Rana -- Toxicity reference values for polybrominated diphenyl ethers: risk assessment for predatory birds and mammals from two chinese lakes / Ruiqing Zhang, Jianyang Guo, Fengchang Wu, Yunsong Mu, John P. Giesy, Hong Chang, Xiaoli Zhao and Chenglian Feng. |
| Record Nr. | UNINA-9910299558503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels ...[et al.]
| Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels ...[et al.] |
| Pubbl/distr/stampa | Washington ; ; [England], : National Academy Press, c2001 |
| Descrizione fisica | 1 online resource (224 p.) |
| Disciplina | 363.1763 |
| Soggetto topico |
Hazardous substances - Risk assessment - United States
Chemicals - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-18464-7
9786610184644 0-309-57011-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Introduction""; ""REVIEW OF THE NAC DOCUMENT""; ""REFERENCES""; ""Roster National Advisory Committee for Acute Exposure Guideline Levels (NAC/AEGL Committee) for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""Past Committee Members""; ""Participants from Cooperative Partner Countries""; ""Other Participants""; ""Oak Ridge National Laboratory Staff""; ""AEGL Program Senior Staff""; ""Appendix""; ""Preface""
""1. Overview of AEGL Program and NAC/AEGL Committee""""HISTORY""; ""PURPOSE AND OBJECTIVES OF THE AEGL PROGRAM AND THE NAC/AEGL COMMITTEE""; ""COMMITTEE MEMBERSHIP AND ORGANIZATIONAL STRUCTURE""; ""SELECTION OF CHEMICALS FOR AEGL DEVELOPMENT""; ""SCIENTIFIC CREDIBILITY OF AEGL VALUES""; ""THE AEGL DEVELOPMENT AND PEER-REVIEW PROCESS""; ""Stage 1: Draft AEGLs""; ""Stage 2: Proposed AEGLs""; ""Stage 3: Interim AEGLs""; ""Stage 4: Final AEGLs""; ""OPERATION OF THE NAC/AEGL COMMITTEE""; ""VALUE OF A COLLABORATIVE EFFORT IN THE AEGL PROGRAM""; ""APPLICATIONS OF THE AEGL VALUES"" ""2. Derivation of AEGL Values""""2.1 CHARACTERIZATION OF AEGLS""; ""2.2 EMPIRICAL TOXICOLOGIC ENDPOINTS AND METHODS FOR DETERMINING EXPOSURE CONCENTRATIONS USED TO DERIVE AEGLS 1, 2, AND 3""; ""2.2.1 Selection of the Highest Exposure Level at Which the Effects That Define an AEGL Are Not Observed""; ""2.2.2 Selection of Health-Effect Endpoints for AEGL-1, AEGL-2, and AEGL-3""; ""2.2.2.1 AEGL-1 Endpoints""; ""2.2.2.1.1 No Value Established�AEGL-1 Is Close to or Exceeds AEGL-2""; ""2.2.2.1.2 No Value Established�Insufficient Data"" ""2.2.2.1.3 Highest Experimental Exposure Without an AEGL-1 Effect""""2.2.2.1.4 Effect Level for a Response""; ""2.2.2.2 AEGL-2 Endpoints""; ""2.2.2.2.1 Highest Experimental Exposure Without an AEGL-2 Effect""; ""2.2.2.2.2 Effect Level for a Toxic Response That Was Not Incapacitating or Not Irreversible""; ""2.2.2.2.3 A Fraction of the AEGL-3 Value""; ""2.2.2.3 AEGL-3 Endpoints""; ""2.2.2.3.1 Highest Exposure Level That Does Not Cause Lethality�Experimentally Observed Threshold (AEGL-3 NOAEL)"" ""2.2.2.3.2 Highest Exposure Level That Does Not Cause Lethality�Estimated Lethality Threshold�One-Third of the LC50""""2.2.2.3.3 Highest Exposure Level That Does Not Cause Lethality�Benchmark Exposure Calculation of the 5% and 1% Response""; ""2.2.2.3.4 Effect Level for a Response""; ""2.3 GUIDELINES AND CRITERIA FOR THE SEARCH STRATEGY, EVALUATION, SELECTION, AND DOCUMENTATION OF KEY DATA AND SUPPORTING�""; ""2.3.1 Search Strategy""; ""2.3.2 Evaluation, Selection, and Documentation of Key and Supporting Data""; ""2.3.3 Elements for Discussion on Data Adequacy and Research Needs"" ""2.4 DOSIMETRY CORRECTIONS FROM ANIMAL TO HUMAN EXPOSURES"" |
| Record Nr. | UNINA-9910456170603321 |
| Washington ; ; [England], : National Academy Press, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels ...[et al.]
| Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels ...[et al.] |
| Pubbl/distr/stampa | Washington ; ; [England], : National Academy Press, c2001 |
| Descrizione fisica | 1 online resource (224 p.) |
| Disciplina | 363.1763 |
| Soggetto topico |
Hazardous substances - Risk assessment - United States
Chemicals - Physiological effect |
| ISBN |
0-309-17086-9
1-280-18464-7 9786610184644 0-309-57011-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Introduction""; ""REVIEW OF THE NAC DOCUMENT""; ""REFERENCES""; ""Roster National Advisory Committee for Acute Exposure Guideline Levels (NAC/AEGL Committee) for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""Past Committee Members""; ""Participants from Cooperative Partner Countries""; ""Other Participants""; ""Oak Ridge National Laboratory Staff""; ""AEGL Program Senior Staff""; ""Appendix""; ""Preface""
""1. Overview of AEGL Program and NAC/AEGL Committee""""HISTORY""; ""PURPOSE AND OBJECTIVES OF THE AEGL PROGRAM AND THE NAC/AEGL COMMITTEE""; ""COMMITTEE MEMBERSHIP AND ORGANIZATIONAL STRUCTURE""; ""SELECTION OF CHEMICALS FOR AEGL DEVELOPMENT""; ""SCIENTIFIC CREDIBILITY OF AEGL VALUES""; ""THE AEGL DEVELOPMENT AND PEER-REVIEW PROCESS""; ""Stage 1: Draft AEGLs""; ""Stage 2: Proposed AEGLs""; ""Stage 3: Interim AEGLs""; ""Stage 4: Final AEGLs""; ""OPERATION OF THE NAC/AEGL COMMITTEE""; ""VALUE OF A COLLABORATIVE EFFORT IN THE AEGL PROGRAM""; ""APPLICATIONS OF THE AEGL VALUES"" ""2. Derivation of AEGL Values""""2.1 CHARACTERIZATION OF AEGLS""; ""2.2 EMPIRICAL TOXICOLOGIC ENDPOINTS AND METHODS FOR DETERMINING EXPOSURE CONCENTRATIONS USED TO DERIVE AEGLS 1, 2, AND 3""; ""2.2.1 Selection of the Highest Exposure Level at Which the Effects That Define an AEGL Are Not Observed""; ""2.2.2 Selection of Health-Effect Endpoints for AEGL-1, AEGL-2, and AEGL-3""; ""2.2.2.1 AEGL-1 Endpoints""; ""2.2.2.1.1 No Value Established�AEGL-1 Is Close to or Exceeds AEGL-2""; ""2.2.2.1.2 No Value Established�Insufficient Data"" ""2.2.2.1.3 Highest Experimental Exposure Without an AEGL-1 Effect""""2.2.2.1.4 Effect Level for a Response""; ""2.2.2.2 AEGL-2 Endpoints""; ""2.2.2.2.1 Highest Experimental Exposure Without an AEGL-2 Effect""; ""2.2.2.2.2 Effect Level for a Toxic Response That Was Not Incapacitating or Not Irreversible""; ""2.2.2.2.3 A Fraction of the AEGL-3 Value""; ""2.2.2.3 AEGL-3 Endpoints""; ""2.2.2.3.1 Highest Exposure Level That Does Not Cause Lethality�Experimentally Observed Threshold (AEGL-3 NOAEL)"" ""2.2.2.3.2 Highest Exposure Level That Does Not Cause Lethality�Estimated Lethality Threshold�One-Third of the LC50""""2.2.2.3.3 Highest Exposure Level That Does Not Cause Lethality�Benchmark Exposure Calculation of the 5% and 1% Response""; ""2.2.2.3.4 Effect Level for a Response""; ""2.3 GUIDELINES AND CRITERIA FOR THE SEARCH STRATEGY, EVALUATION, SELECTION, AND DOCUMENTATION OF KEY DATA AND SUPPORTING�""; ""2.3.1 Search Strategy""; ""2.3.2 Evaluation, Selection, and Documentation of Key and Supporting Data""; ""2.3.3 Elements for Discussion on Data Adequacy and Research Needs"" ""2.4 DOSIMETRY CORRECTIONS FROM ANIMAL TO HUMAN EXPOSURES"" |
| Record Nr. | UNINA-9910780010503321 |
| Washington ; ; [England], : National Academy Press, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals / / Subcommittee on Acute Exposure Guideline Levels ...[et al.]
| Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals / / Subcommittee on Acute Exposure Guideline Levels ...[et al.] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington ; ; [England], : National Academy Press, c2001 |
| Descrizione fisica | 1 online resource (224 p.) |
| Disciplina | 363.1763 |
| Soggetto topico |
Hazardous substances - Risk assessment - United States
Chemicals - Physiological effect |
| ISBN |
0-309-17086-9
1-280-18464-7 9786610184644 0-309-57011-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Introduction""; ""REVIEW OF THE NAC DOCUMENT""; ""REFERENCES""; ""Roster National Advisory Committee for Acute Exposure Guideline Levels (NAC/AEGL Committee) for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""Past Committee Members""; ""Participants from Cooperative Partner Countries""; ""Other Participants""; ""Oak Ridge National Laboratory Staff""; ""AEGL Program Senior Staff""; ""Appendix""; ""Preface""
""1. Overview of AEGL Program and NAC/AEGL Committee""""HISTORY""; ""PURPOSE AND OBJECTIVES OF THE AEGL PROGRAM AND THE NAC/AEGL COMMITTEE""; ""COMMITTEE MEMBERSHIP AND ORGANIZATIONAL STRUCTURE""; ""SELECTION OF CHEMICALS FOR AEGL DEVELOPMENT""; ""SCIENTIFIC CREDIBILITY OF AEGL VALUES""; ""THE AEGL DEVELOPMENT AND PEER-REVIEW PROCESS""; ""Stage 1: Draft AEGLs""; ""Stage 2: Proposed AEGLs""; ""Stage 3: Interim AEGLs""; ""Stage 4: Final AEGLs""; ""OPERATION OF THE NAC/AEGL COMMITTEE""; ""VALUE OF A COLLABORATIVE EFFORT IN THE AEGL PROGRAM""; ""APPLICATIONS OF THE AEGL VALUES"" ""2. Derivation of AEGL Values""""2.1 CHARACTERIZATION OF AEGLS""; ""2.2 EMPIRICAL TOXICOLOGIC ENDPOINTS AND METHODS FOR DETERMINING EXPOSURE CONCENTRATIONS USED TO DERIVE AEGLS 1, 2, AND 3""; ""2.2.1 Selection of the Highest Exposure Level at Which the Effects That Define an AEGL Are Not Observed""; ""2.2.2 Selection of Health-Effect Endpoints for AEGL-1, AEGL-2, and AEGL-3""; ""2.2.2.1 AEGL-1 Endpoints""; ""2.2.2.1.1 No Value Established�AEGL-1 Is Close to or Exceeds AEGL-2""; ""2.2.2.1.2 No Value Established�Insufficient Data"" ""2.2.2.1.3 Highest Experimental Exposure Without an AEGL-1 Effect""""2.2.2.1.4 Effect Level for a Response""; ""2.2.2.2 AEGL-2 Endpoints""; ""2.2.2.2.1 Highest Experimental Exposure Without an AEGL-2 Effect""; ""2.2.2.2.2 Effect Level for a Toxic Response That Was Not Incapacitating or Not Irreversible""; ""2.2.2.2.3 A Fraction of the AEGL-3 Value""; ""2.2.2.3 AEGL-3 Endpoints""; ""2.2.2.3.1 Highest Exposure Level That Does Not Cause Lethality�Experimentally Observed Threshold (AEGL-3 NOAEL)"" ""2.2.2.3.2 Highest Exposure Level That Does Not Cause Lethality�Estimated Lethality Threshold�One-Third of the LC50""""2.2.2.3.3 Highest Exposure Level That Does Not Cause Lethality�Benchmark Exposure Calculation of the 5% and 1% Response""; ""2.2.2.3.4 Effect Level for a Response""; ""2.3 GUIDELINES AND CRITERIA FOR THE SEARCH STRATEGY, EVALUATION, SELECTION, AND DOCUMENTATION OF KEY DATA AND SUPPORTING�""; ""2.3.1 Search Strategy""; ""2.3.2 Evaluation, Selection, and Documentation of Key and Supporting Data""; ""2.3.3 Elements for Discussion on Data Adequacy and Research Needs"" ""2.4 DOSIMETRY CORRECTIONS FROM ANIMAL TO HUMAN EXPOSURES"" |
| Record Nr. | UNINA-9910825510803321 |
| Washington ; ; [England], : National Academy Press, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||