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Biology and Regulation of Blood‑Tissue Barriers / / edited by C. Yan Cheng
Biology and Regulation of Blood‑Tissue Barriers / / edited by C. Yan Cheng
Edizione [1st ed. 2013.]
Pubbl/distr/stampa New York, NY : , : Springer New York : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (380 p.)
Disciplina 362.17
362.1783
Collana Advances in Experimental Medicine and Biology
Soggetto topico Molecular biology
Medicine
Molecular Medicine
Biomedicine, general
ISBN 1-4614-4711-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Regulation of Permeability Across the Blood‑Brain Barrier -- Drug Transporters at Brain Barriers: Expression and Regulation by Neurological Disorders -- The Blood‑Retina Barrier: Tight Junctions and Barrier Modulation -- The Inner Blood‑Retinal Barrier: Molecular Structure and Transport Biology -- Endothelial and Epithelial Barriers in Graft‑Versus‑Host Disease -- Structure and Regulation of Intestinal Epithelial Tight Junctions: Current Concepts and Unanswered Questions -- Polarity Protein Complex Scribble/Lgl/Dlg and Epithelial Cell Barriers -- The Blood‑Biliary Barrier, Tight Junctions and Human Liver Diseases -- The Blood‑Follicle Barrier (Bfb) in Disease and in Ovarian Function -- Physiology and Pathophysiology of the Epithelial Barrier of the Female Reproductive Tract: Role of Ion Channels -- The Blood‑Epididymis Barrier and Human Male Fertility -- Blood‑Tissue Barriers: Morphofunctional and Immunological Aspects of the Blood‑Testis and Blood‑Epididymal Barriers -- Gap Junctions and Blood‑Tissue Barriers -- Transcriptional Regulation of Cell Adhesion at the Blood‑Testis Barrier and Spermatogenesis in the Testis -- c‑Src and c‑Yes are Two Unlikely Partners of Spermatogenesis and Their Roles in Blood‑Testis Barrier Dynamics -- Role of P‑Glycoprotein at the Blood‑Testis Barrier on Adjudin Distribution in the Testis: a Revisit of Recent Data -- The Apical Ectoplasmic Specialization‑Blood‑Testis Barrier Functional Axis is a Novel Target for Male Contraception.
Record Nr. UNINA-9910437623703321
New York, NY : , : Springer New York : , : Imprint : Springer, , 2013
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Cell and tissue banking
Cell and tissue banking
Pubbl/distr/stampa [Dordrecht] : , : Kluwer Academic Publishers, , 2000-
Descrizione fisica 1 online resource
Disciplina 362.1783
Soggetto topico Tissue banks
Cells - Preservation
Preservation of organs, tissues, etc
Cell transplantation
Biological Specimen Banks
Cell Transplantation
Tissue Transplantation
Tissue Banks
Tissue Preservation - methods
Banques de tissus
Cellules - Conservation
Conservation des organes, tissus, etc
Opslag
Conservatie
Weefsel
Cellen (biologie)
Soggetto genere / forma Periodicals.
ISSN 1573-6814
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910140519203321
[Dordrecht] : , : Kluwer Academic Publishers, , 2000-
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Cell and tissue banking
Cell and tissue banking
Pubbl/distr/stampa [Dordrecht] : , : Kluwer Academic Publishers, , 2000-
Descrizione fisica 1 online resource
Disciplina 362.1783
Soggetto topico Tissue banks
Cells - Preservation
Preservation of organs, tissues, etc
Cell transplantation
Biological Specimen Banks
Cell Transplantation
Tissue Transplantation
Tissue Banks
Tissue Preservation - methods
Banques de tissus
Cellules - Conservation
Conservation des organes, tissus, etc
Opslag
Conservatie
Weefsel
Cellen (biologie)
Soggetto genere / forma Periodicals.
ISSN 1573-6814
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNISA-996214098503316
[Dordrecht] : , : Kluwer Academic Publishers, , 2000-
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Donaction : ricerca-azione sul mondo della donazione e i suoi processi comunicativi / Alessandro Fiori, Francesco Sacchetti
Donaction : ricerca-azione sul mondo della donazione e i suoi processi comunicativi / Alessandro Fiori, Francesco Sacchetti
Autore Fiori, Alessandro
Pubbl/distr/stampa Milano : FrancoAngeli, 2015
Descrizione fisica 126 p. : fig. ; 20 cm
Disciplina 362.1783
Altri autori (Persone) Sacchetti, Francesco
Collana La società
Soggetto non controllato Organi - Donazione - Ricerca
ISBN 978-88-917-2688-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione ita
Record Nr. UNINA-990010078410403321
Fiori, Alessandro
Milano : FrancoAngeli, 2015
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Effective public health policy in organ donation : lessons from a universal public health system in Brazil / / Fábio Silveira and Arlene Terezinha Cagol Garcia Badoch
Effective public health policy in organ donation : lessons from a universal public health system in Brazil / / Fábio Silveira and Arlene Terezinha Cagol Garcia Badoch
Autore Silveira Fabio <active 2018->
Pubbl/distr/stampa Cham, Switzerland : , : Springer Nature Switzerland AG, , [2022]
Descrizione fisica 1 online resource (67 pages)
Disciplina 362.1783
Collana SpringerBriefs in public health
Soggetto topico Medical policy - Brazil
Donation of organs, tissues, etc
ISBN 3-030-99288-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910568281503321
Silveira Fabio <active 2018->  
Cham, Switzerland : , : Springer Nature Switzerland AG, , [2022]
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Essentials of tissue and cells banking / / George Galea, Marc Turner and Sharon Zahra (editors)
Essentials of tissue and cells banking / / George Galea, Marc Turner and Sharon Zahra (editors)
Edizione [Second edition.]
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (288 pages)
Disciplina 362.1783
Soggetto topico Tissue banks
Procurement of organs, tissues, etc
Preservation of organs, tissues, etc
Bancs de teixits
Conservació de teixits (Biologia)
Conservació d'òrgans
Soggetto genere / forma Llibres electrònics
ISBN 3-030-71621-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Contents -- 1 Live Donors of Tissue -- Abstract -- 1.1 Introduction -- 1.2 Regulation -- 1.3 Donor Identification -- 1.3.1 Femoral Head Donation -- 1.3.2 Amniotic Membrane Donation -- 1.4 Consent -- 1.5 Donor Selection: Evidence Base and General Considerations -- 1.6 Generic Contraindications -- 1.6.1 Transmissible Infections -- 1.6.2 Acute Infections -- 1.6.3 Risk of Transmission of Prion Diseases -- 1.6.4 Malignancy -- 1.7 Retrieval/Procurement -- 1.8 Summary -- References -- 2 Deceased Tissue Donors -- Abstract -- 2.1 Introduction -- 2.2 Deceased Tissue Donor Identification -- 2.3 The Law and the Role of the Family -- 2.4 Age Cut-Offs -- 2.5 Medical, Behavioural and Social Assessment -- 2.6 Blood Sampling and Haemodilution -- 2.7 Timing and Venue of Retrieval -- 2.8 Retrieval Process -- 2.9 Conclusion -- References -- 3 Banking and Use of Umbilical Cord Blood -- Abstract -- 3.1 Introduction -- 3.2 Donation Programmes -- 3.2.1 Collection Sites -- 3.2.2 Recruitment and Consent -- 3.2.3 Donor Elegibility -- 3.2.4 Collection Techniques -- 3.2.5 Donor Follow up -- 3.2.6 Non-Frozen Transportation -- 3.3 Umbilical Cord Blood Processing and Storage -- 3.3.1 Banking Structure and Resources -- 3.3.2 Reception and Process Acquisition -- 3.3.3 Volume Reduction -- 3.3.4 Cryopreservation -- 3.3.5 Testing and Product Conformity -- 3.3.6 Inventory Management -- 3.4 Use of Umbilical Cord Blood for Transplantation -- 3.4.1 Selection Principles -- 3.4.2 Request for Shipping -- 3.4.3 Frozen Transportation -- 3.4.4 Thawing and Infusion -- 3.4.5 Transplantation Outcomes -- 3.5 Future Challenges for Umbilical Cord Blood Banking -- References -- 4 Ocular Tissue Banking -- Abstract -- 4.1 Eye Donation -- 4.2 Corneal Transplantation -- 4.3 Corneal Storage -- 4.4 Hypothermia -- 4.5 Organ Culture -- 4.6 Limbal Stem Cells.
4.7 Extending the Role of Eye Banks -- 4.8 Other Cell-Based Therapies for Ocular Disease -- References -- 5 Banking of Heart Valves -- Abstract -- 5.1 Introduction -- 5.2 Selection Criteria -- 5.3 Processing and Disinfection of Heart Valves -- 5.4 Quality Assurance of Heart Valves -- 5.5 Current Issues in Heart Valve Banking -- 5.5.1 Mechanical Properties of Valves -- 5.6 Decellularization -- 5.7 Vitrification -- 5.8 Matching of Valves -- 5.9 Centralised Supply -- 5.10 Conclusions -- References -- 6 Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Abstract -- 6.1 Introduction -- 6.2 Transportation of HPC Product from the Collection Site to Stem Cell Laboratory -- 6.3 Receipt and Initial Storage of HPC Products -- 6.4 Preparation of HPC Products for Cryopreservation -- 6.5 Cryopreservation of HPC Products -- 6.6 Rate of Freezing -- 6.7 Storage of HPC Products -- 6.8 Transport of Frozen HPC Products -- 6.9 Further Processing Performed by Stem Cell Laboratories -- 6.9.1 Bone Marrow (HPC,M) Processing -- 6.9.2 Selection/Depletion -- 6.9.3 Campath in the Bag -- 6.10 Quality Control of the HPC Product -- 6.11 Quality Control Post Cryopreservation -- 6.12 Conclusion -- References -- 7 Storage, Processing and Preservation -- Abstract -- 7.1 Introduction -- 7.1.1 Tissue Replacement -- 7.1.2 Autologous Versus Allogeneic Grafts -- 7.1.3 Immunological Reponses to Tissue Allografts -- 7.2 Principles of Tissue Preservation -- 7.2.1 Preservation of Non Viable Tissue Grafts -- 7.2.1.1 Causes of Degradation -- 7.2.1.2 Reduction of Water Activity -- Freeze-Drying (Lyophilisation) -- Deep Freezing -- High Concentration Solutes -- 7.2.1.3 Cell Removal -- 7.2.2 Preservation of Viable Tissue Grafts -- 7.3 Principles of Disinfection and Sterilisation -- 7.3.1 Definitions -- 7.3.2 Disinfection Methods -- 7.3.2.1 Viable Tissues -- 7.3.2.2 Non-viable Tissues.
7.3.3 Sterilisation Methods -- 7.3.3.1 Physical Methods -- 7.3.3.2 Chemical Methods -- References -- 8 Cryopreservation in Tissue Banking -- Abstract -- 8.1 Introduction -- 8.2 Critical Impact of Ice Formation -- 8.3 The Role of Added Cryoprotectants -- 8.4 Sample Thawing -- 8.5 Spheroid and Organoid Cryopreservation -- 8.6 Toward the Cryopreservation of Organs and Biopsies -- 8.7 Quality Issues -- 8.8 Sterility, Handling and Contamination Issues -- 8.9 Conclusion -- References -- 9 Sterilisation by Irradiation -- Abstract -- 9.1 Introduction -- 9.2 Specificity of Radiation Sterilisation with Gamma Rays and Electron Beams -- 9.3 Dosimetry for Radiation Sterilisation -- 9.4 Mechanisms Involved in the Inactivation of Micro-organisms by Ionising Radiation -- 9.5 Radiation Resistance of Micro-organisms -- 9.6 Summary and Conclusions -- References -- 10 Screening the Tissue Donor for Infectious Agents -- Abstract -- 10.1 Introduction -- 10.2 Sample Quality -- 10.2.1 Living v. Deceased Donors -- 10.2.1.1 Donor Selection -- 10.2.1.2 Laboratory Screening -- 10.2.2 Haemodilution -- 10.2.3 Screening Targets -- 10.3 Range of Infectious Agents -- 10.3.1 Mandatory Screening -- 10.3.2 Additional/Selective Screening -- 10.3.3 Screening for Other Infectious Agents -- 10.4 Emerging Infectious Threats -- 10.5 Screening Strategy -- 10.5.1 Screening Algorithms -- 10.6 Screening Assays -- 10.6.1 Serological Screening Assays -- 10.6.2 Molecular Screening Assays -- 10.7 Residual Risk -- 10.7.1 Window Period -- 10.8 Conclusions -- References -- 11 Contamination in the Tissue Way -- Abstract -- 11.1 Introduction -- 11.1.1 Bacteria and Fungi -- 11.2 The Tissue Way, P.L.C. Petit [22] -- 11.2.1 Donor -- 11.2.2 Tissue Retrieval in mortuary (1) or operating theatre (2) -- 11.2.3 Transport -- 11.2.4 Tissue Establishment -- 11.2.5 Microbiology Laboratory -- 11.3 Specific Items.
11.4 Future -- References -- 12 Establishing a Quality System in a Tissue Establishment -- 12.1 Background -- 12.2 The History of Quality Management -- 12.3 Why a Quality Management System -- 12.4 Why Quality? -- 12.5 What is Quality? -- 12.6 Examples of Methods to Be Used in Quality -- 12.7 Available Standards and International Legal Documents -- 12.8 Setting Up a Quality System -- 12.9 Risk Management -- 12.10 Applying a Quality System to Your Activities -- 12.10.1 Where Do I Start? -- 12.11 Biovigilance -- 12.12 Quality Systems and IT -- 12.13 Data Protection -- 12.14 The Cost of Quality -- 12.14.1 The Cost of Quality Can Be Categorized into Four Categories -- 12.15 Role of Management and Quality Management Review -- 12.16 Conclusion -- References -- 13 IT System Requirements for Tissue and Cell Banking -- Abstract -- 13.1 Introduction -- 13.2 Why Introduce an IT System? -- 13.3 The Benefits of an IT System -- 13.4 What Are the Operational Requirements? -- 13.5 Developing the Operational Requirements Document (ORD) -- 13.5.1 Functional Requirements -- 13.5.2 Non-functional Requirements -- 13.6 Technology Solutions -- 13.7 Managing the Data -- 13.7.1 Barcodes -- 13.7.2 Radio Frequency Identification (RFID) -- 13.7.3 OCR/ICR/Touch Screens -- 13.7.4 Electronic System Interfaces -- 13.8 Database Management Technology -- 13.9 Selecting an IT System -- 13.10 Cost of an IT System -- 13.11 Implementing an IT System -- 13.11.1 Define Success -- 13.11.2 Set Priorities -- 13.11.3 Avoid Modifications -- 13.11.4 Prepare for Change -- 13.11.5 Gain Executive Support -- 13.11.6 People -- 13.12 Implementation Approach -- 13.13 System Validation -- 13.14 User Training -- 13.15 Managing an IT System -- 13.16 Conclusions -- References -- 14 Ethical and Regulatory Aspects of Cell and Tissue Banking -- Abstract -- 14.1 Introduction -- 14.2 Ethical Issues.
14.2.1 Donor Consent -- 14.2.1.1 Types of Consent -- 14.2.1.2 Capacity to Consent -- Saviour Siblings -- Cord Blood -- 14.2.1.3 Informed Consent -- 14.2.2 Voluntary Donation -- 14.2.3 Property Rights -- 14.2.3.1 Commercialisation -- 14.2.4 Confidentiality -- 14.2.5 Certification of Death -- 14.2.6 Just Access -- 14.2.7 Safety Issues -- 14.2.7.1 Infrastructure and Procedures -- 14.2.7.2 Healthcare Personnel -- 14.3 Societal Issues -- 14.3.1 Altruism -- 14.3.2 Education -- 14.3.3 Cross-Border Exchange -- 14.3.4 Trafficking -- 14.4 Regulatory Instruments -- 14.4.1 Donor Consent -- 14.4.2 Transplant Institutions -- 14.4.3 Data Protection -- 14.4.4 Training -- 14.5 Special Considerations for Cellular Therapies -- 14.5.1 Capacity to Consent -- 14.5.2 Limits of Certainty of Consent -- 14.5.3 Scope of Consent -- 14.5.4 Duration of Consent -- 14.5.5 Commercialisation -- 14.6 The Future -- 15 Human Embryonic Stem Cell Banking for Clinical Applications-20 Years from Their Isolation -- Abstract -- 15.1 Introduction -- 15.2 Human Embryonic Versus Induced Pluripotent Stem Cells as Clinical Source Material -- 15.3 Human Embryonic Stem Cell-Based Therapies -- 15.3.1 Currently Under Clinical Evaluation -- 15.3.2 Clinically Qualified Source Materials -- 15.4 Consensus Standards for Cell Banking -- 15.4.1 Ethics -- 15.4.2 Data Standardisation -- 15.5 Basic Scientific Developments Impacting on Quality Control and Safety -- 15.5.1 Genetic and Epigenetic Instability Affecting Lineage and Oncogenic Potential -- 15.6 Summary -- References -- Index.
Record Nr. UNINA-9910488724503321
Cham, Switzerland : , : Springer, , [2021]
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La donazione degli organi : prospettive antropologiche / a cura di Luigigiovanni Quarta
La donazione degli organi : prospettive antropologiche / a cura di Luigigiovanni Quarta
Pubbl/distr/stampa Bologna, : il Mulino, 2023
Descrizione fisica 319 p. ; 22 cm
Disciplina 174.297954
362.1783
Collana Percosi, Antropologia
Soggetto non controllato Organi - Donazione
ISBN 9788815386427
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione ita
Record Nr. UNINA-9910750400803321
Bologna, : il Mulino, 2023
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Moral Conflicts of Organ Retrieval : A Case for Constructive Pluralism / / Charles C. Hinkley II
Moral Conflicts of Organ Retrieval : A Case for Constructive Pluralism / / Charles C. Hinkley II
Autore Hinkley Charles C., II
Pubbl/distr/stampa Leiden; ; Boston : , : BRILL, , 2005
Descrizione fisica 1 online resource (247 p.)
Disciplina 362.1783
Collana Value Inquiry Book Series
Soggetto topico Procurement of organs, tissues, etc - Moral and ethical aspects
Tissue and Organ Harvesting - ethics
Tissue and Organ Procurement - ethics
Tissue Donors - ethics
Transplantation of organs, tissues, etc - Moral and ethical aspects
ISBN 94-012-0178-1
1-4237-9193-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Acknowledgments -- Introduction -- Part 1: A Philosophical Framework -- 1 Dilemmas, Conflicts, and Residue -- 1 Terminology -- 2 Moral Residue -- 3 Epistemology and Ontology of Dilemmas -- 4 Dilemmas and Deontic Logic -- 5 Guilt, Regret, and Remorse -- 6 Autonomy and Wrongdoing -- 7 Survivor's Guilt -- 8 The Nature of Emotion -- 9 Residual Requirements to Act -- 10 Can We Do without Residue? -- 11 Intuitively Knowing Dilemmas -- 12 Conclusion -- 2 Medical Ethics and Its Limitations -- 1 Cliff's Choice -- 2 Beauchamp and Childress's Principlism -- 3 Virtue Ethics -- 4 Feminist Bioethics -- 5 Case Analysis -- 6 Engelhardt's Postmodern Libertarianism -- 7 Gert, Culver, and Clouser on Common Morality -- 8 Cliff's Choice Revisited -- 9 Conclusion -- 3 Pluralism, Incommensurability, and Weighing -- 1 Moral Pluralism -- 2 Incommensurability -- 3 Covering Values -- 4 The Plurality of Values -- 5 The Calculation of Values -- 6 The Irresolvability of Conflict -- 7 Education and Skill -- 8 Merited Desire Strength -- 9 Weighing Our Options -- 10 Conclusion -- Part 2: Conflicts of Organ Retrieval -- 4 Transplant Recipients' Quality of Life -- 1 Heart Transplants -- 2 Liver Transplants -- 3 Kidney Transplants -- 4 Conclusion -- 5 Can We Wrong the Dead? -- 1 Bioethics and Patient Autonomy -- 2 The Pitcher-Feinberg Thesis -- 3 Callahan's Challenge -- 4 Serafini's Thesis -- 5 Symbolic Action and the Preferences of the Living -- 6 For the Living -- 7 Conclusion -- 6 Defining Death -- 1 Historical Background for the Whole-Brain Definition of Death -- 2 Problems with the Whole-Brain Definition of Death -- 3 The Higher-Brain Definition -- 4 Revisiting the Whole-Brain Definition -- 5 The Cardiopulmonary Definition -- 6 Renewed Challenges to Whole Brain Death -- 7 Is Defining Death a Moral Issue? -- 8 Conclusion -- 7 The Selling of Organs -- 1 Models of Organ Vending -- 2 Cultural Values and Meaning -- 3 Financial Incentives and the Supply of Organs -- 4 Commodification -- 5 Defenders of Organ Sales and Their Critics -- 6 Risks of Living Donation -- 7 Respect for Persons -- 8 Cadaveric Organ Sales and the Altruistic Tradition -- 9 Conclusion -- 8 Xenografts -- 1 Historical Background -- 2 Qualitative Distinctions and Human Privilege -- 3 Risks to Third Parties -- 4 Responding to Risk -- 5 The Prospects of Xenografts -- 6 Conclusion -- 9 Stem Cell Research -- 1 United States Policy -- 2 The Moral Status of Early Human Life Forms -- 3 Property Rights -- 4 Adult Stem Cells -- 5 iPSCs -- 6 Conclusion -- Part 3: A Philosophical Response -- 10 The Regulative Principle -- 1 Marcus's Regulative Principle -- 2 Mothersill on the Regulative Principle -- 3 The Regulative Principle and Dilemmas -- 4 The Regulative Principle and Conflicts -- 5 Implications for Prevention -- 6 Prevention -- 7 Conclusion -- 11 Constructive Pluralism -- 1 Rationality amid Incommensurability -- 2 Routine Retrieval, Presumed Consent, and Familial Consent -- 3 The Definition of Death -- 4 Selling Organs -- 5 Xenotransplants -- 6 Stem Cell Research -- 7 Additional Strategies -- 8 Sets of Strategies -- 9 Conclusion -- Conclusion -- Bibliography -- Author Index -- subject Index.
Altri titoli varianti A Case for Constructive Pluralism
Record Nr. UNINA-9910777651003321
Hinkley Charles C., II  
Leiden; ; Boston : , : BRILL, , 2005
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Moral conflicts of organ retrieval : a case for constructive pluralism / / Charles C. Hinkley II
Moral conflicts of organ retrieval : a case for constructive pluralism / / Charles C. Hinkley II
Autore Hinkley Charles C
Edizione [1st ed.]
Pubbl/distr/stampa Amsterdam ; ; New York, NY, : Rodopi, 2005
Descrizione fisica 1 online resource (247 p.)
Disciplina 362.1783
Collana Value inquiry book series
Values in bioethics
Soggetto topico Procurement of organs, tissues, etc - Moral and ethical aspects
Transplantation of organs, tissues, etc - Moral and ethical aspects
ISBN 94-012-0178-1
1-4237-9193-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Acknowledgments -- Introduction -- Part 1: A Philosophical Framework -- 1 Dilemmas, Conflicts, and Residue -- 1 Terminology -- 2 Moral Residue -- 3 Epistemology and Ontology of Dilemmas -- 4 Dilemmas and Deontic Logic -- 5 Guilt, Regret, and Remorse -- 6 Autonomy and Wrongdoing -- 7 Survivor's Guilt -- 8 The Nature of Emotion -- 9 Residual Requirements to Act -- 10 Can We Do without Residue? -- 11 Intuitively Knowing Dilemmas -- 12 Conclusion -- 2 Medical Ethics and Its Limitations -- 1 Cliff's Choice -- 2 Beauchamp and Childress's Principlism -- 3 Virtue Ethics -- 4 Feminist Bioethics -- 5 Case Analysis -- 6 Engelhardt's Postmodern Libertarianism -- 7 Gert, Culver, and Clouser on Common Morality -- 8 Cliff's Choice Revisited -- 9 Conclusion -- 3 Pluralism, Incommensurability, and Weighing -- 1 Moral Pluralism -- 2 Incommensurability -- 3 Covering Values -- 4 The Plurality of Values -- 5 The Calculation of Values -- 6 The Irresolvability of Conflict -- 7 Education and Skill -- 8 Merited Desire Strength -- 9 Weighing Our Options -- 10 Conclusion -- Part 2: Conflicts of Organ Retrieval -- 4 Transplant Recipients' Quality of Life -- 1 Heart Transplants -- 2 Liver Transplants -- 3 Kidney Transplants -- 4 Conclusion -- 5 Can We Wrong the Dead? -- 1 Bioethics and Patient Autonomy -- 2 The Pitcher-Feinberg Thesis -- 3 Callahan's Challenge -- 4 Serafini's Thesis -- 5 Symbolic Action and the Preferences of the Living -- 6 For the Living -- 7 Conclusion -- 6 Defining Death -- 1 Historical Background for the Whole-Brain Definition of Death -- 2 Problems with the Whole-Brain Definition of Death -- 3 The Higher-Brain Definition -- 4 Revisiting the Whole-Brain Definition -- 5 The Cardiopulmonary Definition -- 6 Renewed Challenges to Whole Brain Death -- 7 Is Defining Death a Moral Issue? -- 8 Conclusion -- 7 The Selling of Organs -- 1 Models of Organ Vending -- 2 Cultural Values and Meaning -- 3 Financial Incentives and the Supply of Organs -- 4 Commodification -- 5 Defenders of Organ Sales and Their Critics -- 6 Risks of Living Donation -- 7 Respect for Persons -- 8 Cadaveric Organ Sales and the Altruistic Tradition -- 9 Conclusion -- 8 Xenografts -- 1 Historical Background -- 2 Qualitative Distinctions and Human Privilege -- 3 Risks to Third Parties -- 4 Responding to Risk -- 5 The Prospects of Xenografts -- 6 Conclusion -- 9 Stem Cell Research -- 1 United States Policy -- 2 The Moral Status of Early Human Life Forms -- 3 Property Rights -- 4 Adult Stem Cells -- 5 iPSCs -- 6 Conclusion -- Part 3: A Philosophical Response -- 10 The Regulative Principle -- 1 Marcus's Regulative Principle -- 2 Mothersill on the Regulative Principle -- 3 The Regulative Principle and Dilemmas -- 4 The Regulative Principle and Conflicts -- 5 Implications for Prevention -- 6 Prevention -- 7 Conclusion -- 11 Constructive Pluralism -- 1 Rationality amid Incommensurability -- 2 Routine Retrieval, Presumed Consent, and Familial Consent -- 3 The Definition of Death -- 4 Selling Organs -- 5 Xenotransplants -- 6 Stem Cell Research -- 7 Additional Strategies -- 8 Sets of Strategies -- 9 Conclusion -- Conclusion -- Bibliography -- Author Index -- subject Index.
Record Nr. UNINA-9910806242103321
Hinkley Charles C  
Amsterdam ; ; New York, NY, : Rodopi, 2005
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Moral Conflicts of Organ Retrieval : A Case for Constructive Pluralism / / Charles C. Hinkley II
Moral Conflicts of Organ Retrieval : A Case for Constructive Pluralism / / Charles C. Hinkley II
Autore II Charles C. Hinkley
Pubbl/distr/stampa Leiden; ; Boston : , : BRILL, , 2005
Descrizione fisica 1 online resource (247 p.)
Disciplina 362.1783
Collana Value Inquiry Book Series
Soggetto topico Procurement of organs, tissues, etc - Moral and ethical aspects
Tissue and Organ Harvesting - ethics
Tissue and Organ Procurement - ethics
Tissue Donors - ethics
Transplantation of organs, tissues, etc - Moral and ethical aspects
Soggetto genere / forma Electronic books.
ISBN 94-012-0178-1
1-4237-9193-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Acknowledgments -- Introduction -- Part 1: A Philosophical Framework -- 1 Dilemmas, Conflicts, and Residue -- 1 Terminology -- 2 Moral Residue -- 3 Epistemology and Ontology of Dilemmas -- 4 Dilemmas and Deontic Logic -- 5 Guilt, Regret, and Remorse -- 6 Autonomy and Wrongdoing -- 7 Survivor's Guilt -- 8 The Nature of Emotion -- 9 Residual Requirements to Act -- 10 Can We Do without Residue? -- 11 Intuitively Knowing Dilemmas -- 12 Conclusion -- 2 Medical Ethics and Its Limitations -- 1 Cliff's Choice -- 2 Beauchamp and Childress's Principlism -- 3 Virtue Ethics -- 4 Feminist Bioethics -- 5 Case Analysis -- 6 Engelhardt's Postmodern Libertarianism -- 7 Gert, Culver, and Clouser on Common Morality -- 8 Cliff's Choice Revisited -- 9 Conclusion -- 3 Pluralism, Incommensurability, and Weighing -- 1 Moral Pluralism -- 2 Incommensurability -- 3 Covering Values -- 4 The Plurality of Values -- 5 The Calculation of Values -- 6 The Irresolvability of Conflict -- 7 Education and Skill -- 8 Merited Desire Strength -- 9 Weighing Our Options -- 10 Conclusion -- Part 2: Conflicts of Organ Retrieval -- 4 Transplant Recipients' Quality of Life -- 1 Heart Transplants -- 2 Liver Transplants -- 3 Kidney Transplants -- 4 Conclusion -- 5 Can We Wrong the Dead? -- 1 Bioethics and Patient Autonomy -- 2 The Pitcher-Feinberg Thesis -- 3 Callahan's Challenge -- 4 Serafini's Thesis -- 5 Symbolic Action and the Preferences of the Living -- 6 For the Living -- 7 Conclusion -- 6 Defining Death -- 1 Historical Background for the Whole-Brain Definition of Death -- 2 Problems with the Whole-Brain Definition of Death -- 3 The Higher-Brain Definition -- 4 Revisiting the Whole-Brain Definition -- 5 The Cardiopulmonary Definition -- 6 Renewed Challenges to Whole Brain Death -- 7 Is Defining Death a Moral Issue? -- 8 Conclusion -- 7 The Selling of Organs -- 1 Models of Organ Vending -- 2 Cultural Values and Meaning -- 3 Financial Incentives and the Supply of Organs -- 4 Commodification -- 5 Defenders of Organ Sales and Their Critics -- 6 Risks of Living Donation -- 7 Respect for Persons -- 8 Cadaveric Organ Sales and the Altruistic Tradition -- 9 Conclusion -- 8 Xenografts -- 1 Historical Background -- 2 Qualitative Distinctions and Human Privilege -- 3 Risks to Third Parties -- 4 Responding to Risk -- 5 The Prospects of Xenografts -- 6 Conclusion -- 9 Stem Cell Research -- 1 United States Policy -- 2 The Moral Status of Early Human Life Forms -- 3 Property Rights -- 4 Adult Stem Cells -- 5 iPSCs -- 6 Conclusion -- Part 3: A Philosophical Response -- 10 The Regulative Principle -- 1 Marcus's Regulative Principle -- 2 Mothersill on the Regulative Principle -- 3 The Regulative Principle and Dilemmas -- 4 The Regulative Principle and Conflicts -- 5 Implications for Prevention -- 6 Prevention -- 7 Conclusion -- 11 Constructive Pluralism -- 1 Rationality amid Incommensurability -- 2 Routine Retrieval, Presumed Consent, and Familial Consent -- 3 The Definition of Death -- 4 Selling Organs -- 5 Xenotransplants -- 6 Stem Cell Research -- 7 Additional Strategies -- 8 Sets of Strategies -- 9 Conclusion -- Conclusion -- Bibliography -- Author Index -- subject Index.
Altri titoli varianti A Case for Constructive Pluralism
Record Nr. UNINA-9910451537603321
II Charles C. Hinkley  
Leiden; ; Boston : , : BRILL, , 2005
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