Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Case study application of determining end of asset physical life using survival analysis / / by Duncan Rose [and three others] ; in collaboration with Greater Cincinnati Water Works and the Metropolitan Sewer District of Greater Cincinnati
| Case study application of determining end of asset physical life using survival analysis / / by Duncan Rose [and three others] ; in collaboration with Greater Cincinnati Water Works and the Metropolitan Sewer District of Greater Cincinnati |
| Pubbl/distr/stampa | Alexandria, Virginia : , : Water Environment Research Foundation, , 2014 |
| Descrizione fisica | 1 online resource (106 p.) |
| Disciplina | 333.9122 |
| Soggetto topico | Water consumption |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-78040-677-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Part 1: Case Study Application of Determining End of Asset Physical Life Using Survival Analysis""; ""Copyright""; ""Acknowledgments""; ""Abstract and Benefits""; ""Table of Contents""; ""List of Tables""; ""List of Figures""; ""Executive Summary""; ""Chapter 1.0: Introduction""; ""Chapter 2.0: Ideal Data Set for End of Asset Life Decision Process""; ""2.1 Dataset to Determine End of Physical Life""; ""2.2 Dataset to Determine End of Economic Life""; ""2.3 Dataset to Determine End of Service Life""; ""Chapter 3.0: Data Attributes""; ""3.1 GCWW/MSD Data Attributes""
""3.2 GCWW/Data Statistics - Water Pipes""""3.3 MSD Data Statistics - Sewer Pipes""; ""3.4 Missing Attributes from Dataset""; ""Chapter 4.0: Data Gaps and Assumptions""; ""4.1 Data Gaps and Assumptions""; ""Chapter 5.0: Data Analysis and Survival Curve Development""; ""5.1 Application of EOAL Tool to Determine End of Physical Life""; ""5.2 GCWW Data - Water Pipes""; ""5.2.1 Overview""; ""5.2.2 Selection of Significant Variables""; ""5.2.3 Development of Survival Model""; ""5.3 Metropolitan Sewer District (MSD) - Sewer Data""; ""5.3.1 Overview""; ""5.3.2 Selection of Significant Variables"" ""5.3.3 Development of Survival Model""""Chapter 6.0: Performance Assessment""; ""6.1 Performance Assessment of EOAL Tool Results""; ""References""; ""Part 2: Case Study Application of Determining End of Physical Life Using Survival Analysis""; ""Copyright""; ""Acknowledgments ""; ""Abstract and Benefits""; ""Table of Contents""; ""List of Tables""; ""List of Figures""; ""List of Acronyms""; ""Executive Summary""; ""Chapter 1.0: Introduction""; ""Chapter 2.0: Introduction to Survivor Analysis""; ""2.1 Overview""; ""2.2 Brief Introduction to Survival Analysis"" ""2.3 Benefits of Survival Analysis""""Chapter 3.0: Data Attributes""; ""3.1 MMSD Data Overview""; ""3.2 MMSD Data - RAS/WAS Pump Attributes""; ""Chapter 4.0: Data Gaps and Assumptions""; ""4.1 Data Gaps and Assumptions""; ""4.2 Definition of Failure""; ""4.3 Distribution of MMSD Assets""; ""Chapter 5.0: Data Analysis and Survival Curves and Development""; ""5.1 Introduction""; ""5.2 Survival Analysis of Motor Assets""; ""5.2.1 Selecting Significant Variables""; ""5.2.2 Non-Parametric Survival Model ""; ""5.2.3 Parametric Survival Model"" ""5.2.4 Comparison of Non-Parametric and Parametric Survival Models""""5.3 Survival Analysis of Pump Assets""; ""5.3.1 Selecting Significant Variables""; ""5.3.2 Non-Parametric Survival Model""; ""5.3.3 Parametric Survival Model""; ""5.3.4 Comparison of Non-Parametric and Parametric Survival Models""; ""5.4 Survival Analysis of Motor and Pump Assets Combined""; ""5.4.1 Selecting Significant Variables""; ""5.4.2 Non-Parametric Survival Model""; ""5.4.3 Parametric Survival Model""; ""5.4.4 Comparison of Non-Parametric and Parametric Survival Models"" ""Chapter 6.0: Discussions and Recommendations"" |
| Record Nr. | UNINA-9910466903203321 |
| Alexandria, Virginia : , : Water Environment Research Foundation, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Case study application of determining end of asset physical life using survival analysis / / by Duncan Rose [and three others] ; in collaboration with Greater Cincinnati Water Works and the Metropolitan Sewer District of Greater Cincinnati
| Case study application of determining end of asset physical life using survival analysis / / by Duncan Rose [and three others] ; in collaboration with Greater Cincinnati Water Works and the Metropolitan Sewer District of Greater Cincinnati |
| Pubbl/distr/stampa | Alexandria, Virginia : , : Water Environment Research Foundation, , 2014 |
| Descrizione fisica | 1 online resource (106 p.) |
| Disciplina | 333.9122 |
| Soggetto topico | Water consumption |
| ISBN | 1-78040-677-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Part 1: Case Study Application of Determining End of Asset Physical Life Using Survival Analysis""; ""Copyright""; ""Acknowledgments""; ""Abstract and Benefits""; ""Table of Contents""; ""List of Tables""; ""List of Figures""; ""Executive Summary""; ""Chapter 1.0: Introduction""; ""Chapter 2.0: Ideal Data Set for End of Asset Life Decision Process""; ""2.1 Dataset to Determine End of Physical Life""; ""2.2 Dataset to Determine End of Economic Life""; ""2.3 Dataset to Determine End of Service Life""; ""Chapter 3.0: Data Attributes""; ""3.1 GCWW/MSD Data Attributes""
""3.2 GCWW/Data Statistics - Water Pipes""""3.3 MSD Data Statistics - Sewer Pipes""; ""3.4 Missing Attributes from Dataset""; ""Chapter 4.0: Data Gaps and Assumptions""; ""4.1 Data Gaps and Assumptions""; ""Chapter 5.0: Data Analysis and Survival Curve Development""; ""5.1 Application of EOAL Tool to Determine End of Physical Life""; ""5.2 GCWW Data - Water Pipes""; ""5.2.1 Overview""; ""5.2.2 Selection of Significant Variables""; ""5.2.3 Development of Survival Model""; ""5.3 Metropolitan Sewer District (MSD) - Sewer Data""; ""5.3.1 Overview""; ""5.3.2 Selection of Significant Variables"" ""5.3.3 Development of Survival Model""""Chapter 6.0: Performance Assessment""; ""6.1 Performance Assessment of EOAL Tool Results""; ""References""; ""Part 2: Case Study Application of Determining End of Physical Life Using Survival Analysis""; ""Copyright""; ""Acknowledgments ""; ""Abstract and Benefits""; ""Table of Contents""; ""List of Tables""; ""List of Figures""; ""List of Acronyms""; ""Executive Summary""; ""Chapter 1.0: Introduction""; ""Chapter 2.0: Introduction to Survivor Analysis""; ""2.1 Overview""; ""2.2 Brief Introduction to Survival Analysis"" ""2.3 Benefits of Survival Analysis""""Chapter 3.0: Data Attributes""; ""3.1 MMSD Data Overview""; ""3.2 MMSD Data - RAS/WAS Pump Attributes""; ""Chapter 4.0: Data Gaps and Assumptions""; ""4.1 Data Gaps and Assumptions""; ""4.2 Definition of Failure""; ""4.3 Distribution of MMSD Assets""; ""Chapter 5.0: Data Analysis and Survival Curves and Development""; ""5.1 Introduction""; ""5.2 Survival Analysis of Motor Assets""; ""5.2.1 Selecting Significant Variables""; ""5.2.2 Non-Parametric Survival Model ""; ""5.2.3 Parametric Survival Model"" ""5.2.4 Comparison of Non-Parametric and Parametric Survival Models""""5.3 Survival Analysis of Pump Assets""; ""5.3.1 Selecting Significant Variables""; ""5.3.2 Non-Parametric Survival Model""; ""5.3.3 Parametric Survival Model""; ""5.3.4 Comparison of Non-Parametric and Parametric Survival Models""; ""5.4 Survival Analysis of Motor and Pump Assets Combined""; ""5.4.1 Selecting Significant Variables""; ""5.4.2 Non-Parametric Survival Model""; ""5.4.3 Parametric Survival Model""; ""5.4.4 Comparison of Non-Parametric and Parametric Survival Models"" ""Chapter 6.0: Discussions and Recommendations"" |
| Record Nr. | UNINA-9910796198703321 |
| Alexandria, Virginia : , : Water Environment Research Foundation, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Case study application of determining end of asset physical life using survival analysis / / by Duncan Rose [and three others] ; in collaboration with Greater Cincinnati Water Works and the Metropolitan Sewer District of Greater Cincinnati
| Case study application of determining end of asset physical life using survival analysis / / by Duncan Rose [and three others] ; in collaboration with Greater Cincinnati Water Works and the Metropolitan Sewer District of Greater Cincinnati |
| Pubbl/distr/stampa | Alexandria, Virginia : , : Water Environment Research Foundation, , 2014 |
| Descrizione fisica | 1 online resource (106 p.) |
| Disciplina | 333.9122 |
| Soggetto topico | Water consumption |
| ISBN | 1-78040-677-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Part 1: Case Study Application of Determining End of Asset Physical Life Using Survival Analysis""; ""Copyright""; ""Acknowledgments""; ""Abstract and Benefits""; ""Table of Contents""; ""List of Tables""; ""List of Figures""; ""Executive Summary""; ""Chapter 1.0: Introduction""; ""Chapter 2.0: Ideal Data Set for End of Asset Life Decision Process""; ""2.1 Dataset to Determine End of Physical Life""; ""2.2 Dataset to Determine End of Economic Life""; ""2.3 Dataset to Determine End of Service Life""; ""Chapter 3.0: Data Attributes""; ""3.1 GCWW/MSD Data Attributes""
""3.2 GCWW/Data Statistics - Water Pipes""""3.3 MSD Data Statistics - Sewer Pipes""; ""3.4 Missing Attributes from Dataset""; ""Chapter 4.0: Data Gaps and Assumptions""; ""4.1 Data Gaps and Assumptions""; ""Chapter 5.0: Data Analysis and Survival Curve Development""; ""5.1 Application of EOAL Tool to Determine End of Physical Life""; ""5.2 GCWW Data - Water Pipes""; ""5.2.1 Overview""; ""5.2.2 Selection of Significant Variables""; ""5.2.3 Development of Survival Model""; ""5.3 Metropolitan Sewer District (MSD) - Sewer Data""; ""5.3.1 Overview""; ""5.3.2 Selection of Significant Variables"" ""5.3.3 Development of Survival Model""""Chapter 6.0: Performance Assessment""; ""6.1 Performance Assessment of EOAL Tool Results""; ""References""; ""Part 2: Case Study Application of Determining End of Physical Life Using Survival Analysis""; ""Copyright""; ""Acknowledgments ""; ""Abstract and Benefits""; ""Table of Contents""; ""List of Tables""; ""List of Figures""; ""List of Acronyms""; ""Executive Summary""; ""Chapter 1.0: Introduction""; ""Chapter 2.0: Introduction to Survivor Analysis""; ""2.1 Overview""; ""2.2 Brief Introduction to Survival Analysis"" ""2.3 Benefits of Survival Analysis""""Chapter 3.0: Data Attributes""; ""3.1 MMSD Data Overview""; ""3.2 MMSD Data - RAS/WAS Pump Attributes""; ""Chapter 4.0: Data Gaps and Assumptions""; ""4.1 Data Gaps and Assumptions""; ""4.2 Definition of Failure""; ""4.3 Distribution of MMSD Assets""; ""Chapter 5.0: Data Analysis and Survival Curves and Development""; ""5.1 Introduction""; ""5.2 Survival Analysis of Motor Assets""; ""5.2.1 Selecting Significant Variables""; ""5.2.2 Non-Parametric Survival Model ""; ""5.2.3 Parametric Survival Model"" ""5.2.4 Comparison of Non-Parametric and Parametric Survival Models""""5.3 Survival Analysis of Pump Assets""; ""5.3.1 Selecting Significant Variables""; ""5.3.2 Non-Parametric Survival Model""; ""5.3.3 Parametric Survival Model""; ""5.3.4 Comparison of Non-Parametric and Parametric Survival Models""; ""5.4 Survival Analysis of Motor and Pump Assets Combined""; ""5.4.1 Selecting Significant Variables""; ""5.4.2 Non-Parametric Survival Model""; ""5.4.3 Parametric Survival Model""; ""5.4.4 Comparison of Non-Parametric and Parametric Survival Models"" ""Chapter 6.0: Discussions and Recommendations"" |
| Record Nr. | UNINA-9910815346303321 |
| Alexandria, Virginia : , : Water Environment Research Foundation, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmacokinetics in risk assessment [[electronic resource] /] / Subcommittee on Disinfectants and Disinfectant By-Products, Safe Drinking Water Committee, Board on Toxicology and Environmental Health Hazards, Assembly of Life Sciences, National Research Council
| Pharmacokinetics in risk assessment [[electronic resource] /] / Subcommittee on Disinfectants and Disinfectant By-Products, Safe Drinking Water Committee, Board on Toxicology and Environmental Health Hazards, Assembly of Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1987 |
| Descrizione fisica | 1 online resource (512 p.) |
| Disciplina | 333.9122 |
| Collana | Drinking water and health |
| Soggetto topico |
Drinking water - Contamination - United States
Drinking water - Contamination Drinking water - Health aspects - United States Drinking water - Health aspects Water - Pollution - Toxicology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-22160-7
9786610221608 0-309-55769-0 0-585-15539-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Pharmacokinetics in Risk Assessment""; ""Copyright""; ""PREFACE""; ""Contents""; ""PART I INTRODUCTION: THE PROBLEM AND AN APPROACH ""; ""Risk Assessment: Historical Perspectives""; ""References""; ""Tissue Dosimetry in Risk Assessment, or What's the Problem Here Anyway?""; ""INTRODUCTION""; ""A DOSE OF WHAT?""; ""ISN'T THIS VOLUME ABOUT PHARMACOKINETICS?""; ""GENOTOXIC CARCINOGENS""; ""PARENT CHEMICAL""; ""STABLE METABOLITES""; ""REACTIVE, NONISOLATABLE METABOLITES""; ""INTERCALATING AGENTS""; ""EPIGENETIC CARCINOGENS""; ""SUMMARY""; ""References""; ""PART II MATHEMATICAL MODELING ""
""Modeling: An Introduction""""References""; ""Physiologically Based Pharmacokinetic Modeling""; ""INTRODUCTION""; ""BIOLOGICAL BASIS OF PHYSIOLOGICAL PHARMACOKINETICS""; ""DEVELOPMENT OF MODELS""; ""CHOICE OF COMPARTMENTS""; ""BASIC MASS BALANCES""; ""Mass Balance: Blood Pool""; ""Mass Balance: Tissue Region i""; ""SIMPLIFICATIONS OF MASS BALANCES""; ""Examples""; ""DISCUSSION""; ""FUTURE RESEARCH NEEDS""; ""References""; ""PART III GENERALIZATIONS AND EXTRAPOLATIONS ""; ""Allometry: Body Size Constraints in Animal Design""; ""INTRODUCTION""; ""SIZE, DESIGN, AND PHARMACOKINETICS"" ""Aerobic Energetics of Muscle In Vivo""""Conflict of Physiological and Chronological Time""; ""Species Extrapolations, Physiological Time, and Pharmacokinetics""; ""CONCLUSIONS""; ""SUMMARY""; ""References""; ""Prediction of In Vivo Parameters of Drug Metabolism and Distribution from In Vitro Studies""; ""IN VITRO PREDICTION OF IN VIVO DRUG METABOLISM""; ""IN VITRO PREDICTION OF IN VIVO DRUG BINDING AND DISTRIBUTION""; ""CONCLUSION""; ""References""; ""Dose, Species, and Route Extrapolation: General Aspects""; ""DIFFERENT PROBLEMS AND OBJECTIVES, DIFFERENT MODELS""; ""Different Mechanisms"" ""GENERAL PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS""""Simplification of Models""; ""Rates of Formation of Complexes""; ""Diffusional Barriers and Modified Fick's Law""; ""Simple PB-PK Models""; ""Basic Parameters fu and R""; ""Nonlinear Kinetics and Lost Concepts""; ""INTERFACE BETWEEN PB-PK MODELS AND CLEARANCES""; ""Organ Availabilities (F), Extraction Ratios (E), and Clearances (CL)""; ""Physiologically Based Linear Compartmental Pharmacokinetic Models""; ""Validity of the Assumption of Virtual Steady State""; ""Calculation of Other Compartmental Model Parameters"" ""Approximations of Terminal Half-Lives""""Approximate Time Required to Approach Steady State""; ""LINEAR PHARMACOKINETIC SYSTEMS""; ""Total Body Clearance""; ""Importance of the Unbound Concentration of Substances""; ""Classification of Organs; Routes of Administration""; ""Non-First-Pass, Nonelimination Organs""; ""Range of Maximum and Minimum Unbound Concentrations in Nonelimination Organs and Repetitive Administration""; ""Non-First-Pass, Elimination Organs""; ""FIRST-PASS, NONELIMINATION ORGANS""; ""First-Pass, Elimination Organs""; ""ROUTE-TO-ROUTE EXTRAPOLATION"" ""Lungs and Skin Administration"" |
| Record Nr. | UNINA-9910455447303321 |
| Washington, D.C., : National Academy Press, 1987 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmacokinetics in risk assessment / / Subcommittee on Disinfectants and Disinfectant By-Products, Safe Drinking Water Committee, Board on Toxicology and Environmental Health Hazards, Assembly of Life Sciences, National Research Council
| Pharmacokinetics in risk assessment / / Subcommittee on Disinfectants and Disinfectant By-Products, Safe Drinking Water Committee, Board on Toxicology and Environmental Health Hazards, Assembly of Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1987 |
| Descrizione fisica | 1 online resource (512 pages) |
| Disciplina | 333.9122 |
| Collana | Drinking water and health |
| Soggetto topico |
Drinking water - Contamination - United States
Drinking water - Contamination Drinking water - Health aspects - United States Drinking water - Health aspects Water - Pollution - Toxicology |
| ISBN |
1-280-22160-7
9786610221608 0-309-55769-0 0-585-15539-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Pharmacokinetics in Risk Assessment""; ""Copyright""; ""PREFACE""; ""Contents""; ""PART I INTRODUCTION: THE PROBLEM AND AN APPROACH ""; ""Risk Assessment: Historical Perspectives""; ""References""; ""Tissue Dosimetry in Risk Assessment, or What's the Problem Here Anyway?""; ""INTRODUCTION""; ""A DOSE OF WHAT?""; ""ISN'T THIS VOLUME ABOUT PHARMACOKINETICS?""; ""GENOTOXIC CARCINOGENS""; ""PARENT CHEMICAL""; ""STABLE METABOLITES""; ""REACTIVE, NONISOLATABLE METABOLITES""; ""INTERCALATING AGENTS""; ""EPIGENETIC CARCINOGENS""; ""SUMMARY""; ""References""; ""PART II MATHEMATICAL MODELING ""
""Modeling: An Introduction"" ""References""; ""Physiologically Based Pharmacokinetic Modeling""; ""INTRODUCTION""; ""BIOLOGICAL BASIS OF PHYSIOLOGICAL PHARMACOKINETICS""; ""DEVELOPMENT OF MODELS""; ""CHOICE OF COMPARTMENTS""; ""BASIC MASS BALANCES""; ""Mass Balance: Blood Pool""; ""Mass Balance: Tissue Region i""; ""SIMPLIFICATIONS OF MASS BALANCES""; ""Examples""; ""DISCUSSION""; ""FUTURE RESEARCH NEEDS""; ""References""; ""PART III GENERALIZATIONS AND EXTRAPOLATIONS ""; ""Allometry: Body Size Constraints in Animal Design""; ""INTRODUCTION""; ""SIZE, DESIGN, AND PHARMACOKINETICS"" ""Aerobic Energetics of Muscle In Vivo"" ""Conflict of Physiological and Chronological Time""; ""Species Extrapolations, Physiological Time, and Pharmacokinetics""; ""CONCLUSIONS""; ""SUMMARY""; ""References""; ""Prediction of In Vivo Parameters of Drug Metabolism and Distribution from In Vitro Studies""; ""IN VITRO PREDICTION OF IN VIVO DRUG METABOLISM""; ""IN VITRO PREDICTION OF IN VIVO DRUG BINDING AND DISTRIBUTION""; ""CONCLUSION""; ""References""; ""Dose, Species, and Route Extrapolation: General Aspects""; ""DIFFERENT PROBLEMS AND OBJECTIVES, DIFFERENT MODELS""; ""Different Mechanisms"" ""GENERAL PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS"" ""Simplification of Models""; ""Rates of Formation of Complexes""; ""Diffusional Barriers and Modified Fick's Law""; ""Simple PB-PK Models""; ""Basic Parameters fu and R""; ""Nonlinear Kinetics and Lost Concepts""; ""INTERFACE BETWEEN PB-PK MODELS AND CLEARANCES""; ""Organ Availabilities (F), Extraction Ratios (E), and Clearances (CL)""; ""Physiologically Based Linear Compartmental Pharmacokinetic Models""; ""Validity of the Assumption of Virtual Steady State""; ""Calculation of Other Compartmental Model Parameters"" ""Approximations of Terminal Half-Lives"" ""Approximate Time Required to Approach Steady State""; ""LINEAR PHARMACOKINETIC SYSTEMS""; ""Total Body Clearance""; ""Importance of the Unbound Concentration of Substances""; ""Classification of Organs; Routes of Administration""; ""Non-First-Pass, Nonelimination Organs""; ""Range of Maximum and Minimum Unbound Concentrations in Nonelimination Organs and Repetitive Administration""; ""Non-First-Pass, Elimination Organs""; ""FIRST-PASS, NONELIMINATION ORGANS""; ""First-Pass, Elimination Organs""; ""ROUTE-TO-ROUTE EXTRAPOLATION""; ""Lungs and Skin Administration"" |
| Record Nr. | UNINA-9910778712203321 |
| Washington, D.C., : National Academy Press, 1987 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmacokinetics in risk assessment / / Subcommittee on Disinfectants and Disinfectant By-Products, Safe Drinking Water Committee, Board on Toxicology and Environmental Health Hazards, Assembly of Life Sciences, National Research Council
| Pharmacokinetics in risk assessment / / Subcommittee on Disinfectants and Disinfectant By-Products, Safe Drinking Water Committee, Board on Toxicology and Environmental Health Hazards, Assembly of Life Sciences, National Research Council |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1987 |
| Descrizione fisica | 1 online resource (512 pages) |
| Disciplina | 333.9122 |
| Collana | Drinking water and health |
| Soggetto topico |
Drinking water - Contamination - United States
Drinking water - Contamination Drinking water - Health aspects - United States Drinking water - Health aspects Water - Pollution - Toxicology |
| ISBN |
9786610221608
9781280221606 1280221607 9780309557696 0309557690 9780585155395 0585155399 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Pharmacokinetics in Risk Assessment""; ""Copyright""; ""PREFACE""; ""Contents""; ""PART I INTRODUCTION: THE PROBLEM AND AN APPROACH ""; ""Risk Assessment: Historical Perspectives""; ""References""; ""Tissue Dosimetry in Risk Assessment, or What's the Problem Here Anyway?""; ""INTRODUCTION""; ""A DOSE OF WHAT?""; ""ISN'T THIS VOLUME ABOUT PHARMACOKINETICS?""; ""GENOTOXIC CARCINOGENS""; ""PARENT CHEMICAL""; ""STABLE METABOLITES""; ""REACTIVE, NONISOLATABLE METABOLITES""; ""INTERCALATING AGENTS""; ""EPIGENETIC CARCINOGENS""; ""SUMMARY""; ""References""; ""PART II MATHEMATICAL MODELING ""
""Modeling: An Introduction"" ""References""; ""Physiologically Based Pharmacokinetic Modeling""; ""INTRODUCTION""; ""BIOLOGICAL BASIS OF PHYSIOLOGICAL PHARMACOKINETICS""; ""DEVELOPMENT OF MODELS""; ""CHOICE OF COMPARTMENTS""; ""BASIC MASS BALANCES""; ""Mass Balance: Blood Pool""; ""Mass Balance: Tissue Region i""; ""SIMPLIFICATIONS OF MASS BALANCES""; ""Examples""; ""DISCUSSION""; ""FUTURE RESEARCH NEEDS""; ""References""; ""PART III GENERALIZATIONS AND EXTRAPOLATIONS ""; ""Allometry: Body Size Constraints in Animal Design""; ""INTRODUCTION""; ""SIZE, DESIGN, AND PHARMACOKINETICS"" ""Aerobic Energetics of Muscle In Vivo"" ""Conflict of Physiological and Chronological Time""; ""Species Extrapolations, Physiological Time, and Pharmacokinetics""; ""CONCLUSIONS""; ""SUMMARY""; ""References""; ""Prediction of In Vivo Parameters of Drug Metabolism and Distribution from In Vitro Studies""; ""IN VITRO PREDICTION OF IN VIVO DRUG METABOLISM""; ""IN VITRO PREDICTION OF IN VIVO DRUG BINDING AND DISTRIBUTION""; ""CONCLUSION""; ""References""; ""Dose, Species, and Route Extrapolation: General Aspects""; ""DIFFERENT PROBLEMS AND OBJECTIVES, DIFFERENT MODELS""; ""Different Mechanisms"" ""GENERAL PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS"" ""Simplification of Models""; ""Rates of Formation of Complexes""; ""Diffusional Barriers and Modified Fick's Law""; ""Simple PB-PK Models""; ""Basic Parameters fu and R""; ""Nonlinear Kinetics and Lost Concepts""; ""INTERFACE BETWEEN PB-PK MODELS AND CLEARANCES""; ""Organ Availabilities (F), Extraction Ratios (E), and Clearances (CL)""; ""Physiologically Based Linear Compartmental Pharmacokinetic Models""; ""Validity of the Assumption of Virtual Steady State""; ""Calculation of Other Compartmental Model Parameters"" ""Approximations of Terminal Half-Lives"" ""Approximate Time Required to Approach Steady State""; ""LINEAR PHARMACOKINETIC SYSTEMS""; ""Total Body Clearance""; ""Importance of the Unbound Concentration of Substances""; ""Classification of Organs; Routes of Administration""; ""Non-First-Pass, Nonelimination Organs""; ""Range of Maximum and Minimum Unbound Concentrations in Nonelimination Organs and Repetitive Administration""; ""Non-First-Pass, Elimination Organs""; ""FIRST-PASS, NONELIMINATION ORGANS""; ""First-Pass, Elimination Organs""; ""ROUTE-TO-ROUTE EXTRAPOLATION""; ""Lungs and Skin Administration"" |
| Record Nr. | UNINA-9910957776403321 |
| Washington, D.C., : National Academy Press, 1987 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Quality and treatment of drinking water II / Volume editor J. Hrubec ; with contributions by R.A. Baumann ... [et al.]
| Quality and treatment of drinking water II / Volume editor J. Hrubec ; with contributions by R.A. Baumann ... [et al.] |
| Pubbl/distr/stampa | Berlin : Springer, c1998 |
| Descrizione fisica | XV, 180 p. : ill. ; 25 cm |
| Disciplina | 333.9122 |
| Collana | The handbook of environmental chemistry, Water pollution |
| Soggetto topico | Acqua - Trattamento |
| ISBN | 3-540-62574-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNIBAS-000009232 |
| Berlin : Springer, c1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. della Basilicata | ||
| ||
Trinkwasser und seine geschlechtsspezifische Wahrnehmung : eine qualitative Untersuchung zu Wasser und Privatisierung / Alexandra Lux, Doris Hayn
| Trinkwasser und seine geschlechtsspezifische Wahrnehmung : eine qualitative Untersuchung zu Wasser und Privatisierung / Alexandra Lux, Doris Hayn |
| Autore | Lux Alexandra |
| Pubbl/distr/stampa | Frankfurt, M., : ISOE, 2008 |
| Descrizione fisica | Online-Ressource |
| Disciplina |
333.9122
300 |
| Altri autori (Persone) | HaynDoris |
| Collana | ISOE-Materialien Soziale Ökologie |
| Soggetto topico |
Geschlechtsunterschied
Privatisierung Trinkwasser Wahrnehmung Wassergüte Wasserwirtschaft Privatisierung - Wasserversorgung Wasserversorgung - Privatisierung |
| Classificazione | 330 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9911054527603321 |
Lux Alexandra
|
||
| Frankfurt, M., : ISOE, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Trinkwasser und seine geschlechtsspezifische Wahrnehmung : eine qualitative Untersuchung zu Wasser und Privatisierung / Alexandra Lux, Doris Hayn
| Trinkwasser und seine geschlechtsspezifische Wahrnehmung : eine qualitative Untersuchung zu Wasser und Privatisierung / Alexandra Lux, Doris Hayn |
| Autore | Lux Alexandra |
| Pubbl/distr/stampa | Frankfurt, M., : ISOE, 2008 |
| Descrizione fisica | Online-Ressource |
| Disciplina |
333.9122
300 |
| Altri autori (Persone) | HaynDoris |
| Collana | ISOE-Materialien Soziale Ökologie |
| Soggetto topico |
Geschlechtsunterschied
Privatisierung Trinkwasser Wahrnehmung Wassergüte Wasserwirtschaft Privatisierung - Wasserversorgung Wasserversorgung - Privatisierung |
| Classificazione | 330 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNISA-996703380703316 |
|
Lux Alexandra
|
||
| Frankfurt, M., : ISOE, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||