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Bipolar disorder : from neuroscience to treatment / / Allan H. Young, Mario F. Juruena, editors
| Bipolar disorder : from neuroscience to treatment / / Allan H. Young, Mario F. Juruena, editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (viii, 325 pages) |
| Disciplina | 616.89506 |
| Collana | Current Topics in Behavioral Neurosciences |
| Soggetto topico |
Bipolar disorder - Treatment
Trastorn bipolar Terapèutica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-72143-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- The Neurobiology of Bipolar Disorder -- 1 Introduction -- 2 Neurotransmitters -- 2.1 Serotoninergic System -- 2.2 Dopaminergic System -- 2.3 Norepinephrinergic System -- 2.4 GABAergic System -- 2.5 Glutamatergic System -- 3 Intracellular Signalling -- 4 Adenylate Cyclase Signalling Pathway -- 5 Neurotrophins and Neurogenesis -- 6 Neuroendocrine -- 7 Conclusion -- References -- The Role of Stress in Bipolar Disorder -- 1 Introduction -- 1.1 Activation of Hormonal Systems After Stress -- 1.2 Stress Hormone Receptors -- 2 Stress Hormone Actions on the Brain in Healthy Individuals -- 2.1 Cellular Effects of Stress Hormones on Brain Circuits -- 2.2 Neuronal Circuits and Cognitive Function -- 3 Changes in Stress Responsiveness in Bipolar Disorder -- 3.1 Imbalance in the Stress System: Importance of Genetic and (Early) Life History -- 3.2 Changes in the HPA Axis in Bipolar Disorder Patients -- 4 Changes in Cognitive Function in Bipolar Disorder Related to Stress -- 4.1 Time-Dependent Changes in Cognitive Processing Following Stress in BD Patients -- 4.2 Network Function in BP Patients and Individuals at Risk for Psychopathology -- 5 Concluding Remarks -- References -- The Role of Genetics in Bipolar Disorder -- 1 Introduction: Why Genetics Matters in the Susceptibility to Bipolar Disorder? -- 2 Bipolar Disorder Is Heritable: Twin, Adoption, and Family Studies -- 3 How Many Genes Modulate the Risk of Bipolar Disorder? Linkage Studies, Candidate Gene Studies, and Genome-Wide Association S... -- 4 Genetic Overlap Between Bipolar Disorder and Other Brain Disorders: Disorder-Specific or General Genetic Influences? -- 5 The Role of Rare Genetic Variants -- 6 Gene x Environment Studies -- 7 Nongenetic Mechanisms Contributing to the Regulation of Gene Expression: Epigenetics -- 8 Current and Future Lines of Research.
9 Conclusion -- References -- Targeting Mitochondrial Dysfunction for Bipolar Disorder -- 1 The Mitochondria -- 1.1 Mitochondria as an Energy Source -- 1.2 Other Functions of Mitochondria -- 2 Reactive Oxygen Species and Oxidative Stress -- 3 Mitochondria in Bipolar Disorder -- 3.1 Possible Mechanisms of Mitochondrial Dysfunction in Bipolar Disorder -- 3.1.1 A Shift from OXPHOS to Glycolysis -- 3.1.2 Creatine Kinase -- 3.1.3 Calcium -- 3.1.4 Increased Oxidative Stress -- 3.1.5 Neurotransmitters -- 3.1.6 Brain-Derived Neurotrophic Factor (BDNF) -- 3.1.7 NAA -- 3.1.8 Bcl-2 -- 3.2 Mitochondrial Genes -- 4 How Conventional Drugs for Bipolar Disorder Relate to Mitochondrial Functioning -- 5 Mitochondrial Potential Treatments -- 5.1 Likely Beneficial -- 5.1.1 PPAR Agonists -- 5.1.2 Minocycline -- 5.1.3 N-Acetyl-Cysteine (NAC) -- 5.1.4 Co-enzyme Q10 -- 5.1.5 Melatonin -- 5.2 Theoretically Beneficial, but No Studies Have Been Published -- 5.2.1 Ebselen -- 5.2.2 Mangosteen -- 5.2.3 Ketogenic Diet -- 5.2.4 Resveratrol -- 5.2.5 Taurine -- 5.3 Unlikely to Be Beneficial -- 5.3.1 Alpha-Lipoic Acid (ALA) -- 5.3.2 Pyrimidines -- 5.4 Potential Risk of a Manic Switch -- 5.4.1 ALC (Acetyl-L-Carnitine) -- 5.4.2 Creatine Monohydrate (CM) -- 5.4.3 SAMe (S-Adenosyl-Methionine) -- 5.5 Vitamins -- 5.5.1 Vitamin A -- 5.5.2 Vitamin C -- 5.5.3 Vitamin D -- 5.5.4 Vitamin E -- 5.5.5 Vitamins B -- 6 Summary -- References -- Intracellular Signaling Cascades in Bipolar Disorder -- 1 Introduction -- 2 Mitochondrial Dysfunction -- 3 Calcium Channel Modulators -- 4 Intracellular Signaling and Inflammation -- 5 Glycogen Synthase Kinase 3-Beta (GSK3β) -- 6 Protein Kinase C (PKC) and Diacylglycerol (DAG) -- 7 Neurotrophins -- 8 Glutamatergic System -- 9 Dopaminergic System -- 10 Neurohormonal System -- 11 Purinergic System and Mania -- 12 Conclusion -- References. Sleep and Circadian Rhythm Disorder in Bipolar Affective Disorder -- 1 Bipolar Affective Disorder -- 2 Circadian Rhythm -- 3 Circadian Rhythm and Bipolar Affective Disorder -- 4 Circadian Rhythm Sleep-Wake Disorders -- 4.1 Delayed Sleep Phase Disorder -- 5 Genetics -- 6 Chronotype -- 7 Melatonin and Cortisol -- 8 Social Zeitgeber Theory -- 9 Circadian Rhythm and Bipolar Disorder -- 10 Conclusion -- References -- Neuroendocrine Stress System in Bipolar Disorder -- 1 Introduction -- 2 Endocrine Axis -- 2.1 Regulation of the Hypothalamic-Pituitary-Adrenal Axis -- 2.2 The Glucocorticoid Receptor (GR) -- 2.3 Mineralocorticoid Receptors (MRs) -- 2.4 Molecular Mechanisms for Resistance of Glucocorticoid Receptors -- 3 Abnormalities of the HPA Axis in Depression -- 3.1 Impact of Stress on Bipolar Disorders -- 3.2 Impact of Mediating Factors on the HPA Axis -- 4 Factors Associated with an Endophenotype Increasing Vulnerability -- 5 Conclusion -- References -- Neuroanatomic and Functional Neuroimaging Findings -- 1 Introduction -- 2 Structural Neuroimaging and Diffusion Tensor Imaging Studies -- 2.1 Structural Magnetic Resonance Imaging MRI (sMRI) Findings in BD -- 2.2 Diffusion Tensor Imaging (DTI) Findings in BD -- 2.3 Longitudinal sMRI and DTI Findings -- 3 Functional Neuroimaging -- 3.1 Positron Emission Tomography (PET) -- 3.2 Resting-State Functional MRI (rsfMRI) -- 4 Summary of Main Findings -- 5 Diagnostic Specificity of Neuroimaging Findings -- 5.1 Structural Neuroimaging and DTI Findings -- 5.2 Functional Neuroimaging Findings (PET, rs-fMRI) -- 5.3 Neuroimaging and Pattern Classification Methods and the Diagnosis of BD -- 6 Perspectives on the Role of Neuroimaging in the Management of BD Patients -- 6.1 Neuroimaging Studies and Bipolar Disorders Mood States -- 6.2 Neuroimaging Studies, Bipolar Disorders, and Pharmacological Treatment. 6.3 Neuroimaging to Predict Pharmacological Treatment Response -- 6.4 Neuroimaging and Psychotherapy in Bipolar Disorders -- 7 Conclusions -- References -- Structural and Functional Brain Correlates of Neuroprogression in Bipolar Disorder -- 1 Introduction -- 2 Structural Aspects of Neuroprogression in Neuroimaging -- 2.1 Evidence from Cross-Sectional Studies -- 2.1.1 Brain Volume and General Findings -- 2.1.2 Prefrontal Cerebral Cortex -- 2.1.3 Cingulate Cortex -- 2.1.4 Temporal-Limbic Structures -- 2.1.5 Other Brain Structures -- 2.2 Evidence from Longitudinal Studies -- 2.2.1 Brain Volume and General Findings -- 2.2.2 Prefrontal Cerebral Cortex -- 2.2.3 Cingulate Cortex -- 2.2.4 Temporal-Limbic Structures -- 3 Functional Aspects of Neuroprogression in Neuroimaging -- 4 Challenges (Limitations) and Perspectives -- References -- Inflammation as a Mechanism of Bipolar Disorder Neuroprogression -- 1 Introduction -- 2 Evidence of Inflammatory and Infectious Diseases in BD Neuroprogression -- 2.1 Maternal Immune Activation as a Risk Factor for BD Development and Neuroprogression -- 2.2 Role of Infectious Disease as a Trigger to Develop BD Neuroprogression -- 2.3 Autoimmune Disorders and Their Association with BD Neuroprogression -- 2.4 Role of the Gut-Brain Axis on BD Neuroprogression -- 3 Inflammatory and Oxidative Mechanisms in BD Neuroprogression -- 3.1 Mechanisms of Inflammation and Their Contribution to BD Neuroprogression -- 3.2 Oxidative Stress and Mitochondrial Dysfunction Associated with BD Neuroprogression -- 3.3 Peripheral Inflammatory Mediators as a Trigger or Accelerator of BD Neuroprogression -- 3.4 Cerebrospinal Fluid (CSF) System Inflammatory Markers in BD Neuroprogression -- 3.5 Postmortem Inflammatory Markers in BD Neuroprogression -- 4 Conclusions and Future Directions -- References -- Neuropsychology of Bipolar Disorder. 1 Pattern and Magnitude of Impairment -- 2 What Are the Factors that Affect Cognition? -- 2.1 Diagnostic Features -- 2.2 Sleep -- 2.3 Physical Health -- 2.4 Medication -- 3 Summary -- 4 Methods of Assessment -- 4.1 Longitudinal Changes -- 4.2 Identifying Neuropsychological Phenotypic Clusters -- 4.3 Hierarchical Organization of Cognition -- 4.4 Experimental Analysis Methods -- 5 Conclusions -- References -- The Kindling/Sensitization Model and Early Life Stress -- 1 Introduction -- 2 Stress Sensitization -- 3 Stimulant-Induced Behavioral Sensitization -- 4 Episode-Induced Sensitization -- 5 Cross-Sensitization: Neurochemical Commonalities and Inflammatory Mechanisms -- 6 An Epigenetic Basis for Sensitization -- 7 One Genetic and Two Epigenetic Bases for Illness Vulnerability -- 8 More Stress, Episodes, and Substance Abuse in the USA Than Europe Driving Sensitization -- 9 Implications for Treatment -- 10 High Risk Children Deserve Special Attention and Treatment -- 11 Measures Considered for Primary and Secondary Prevention -- 12 Conclusions -- References -- Childhood Maltreatment in Bipolar Disorders -- 1 Introduction -- 2 Childhood Maltreatment and (More Severe) Bipolar Disorders -- 2.1 Childhood Maltreatment as a Risk Factor for Developing Bipolar Disorders -- 2.2 Childhood Maltreatment and the Severity of the Clinical Expression of Bipolar Disorders -- 2.3 Childhood Maltreatment, Psychiatric, and Medical Comorbidities in Bipolar Disorders -- 2.4 Issues About Childhood Maltreatment Subtypes, the Timing of Exposure, and Gender -- 3 Moving to Dimensions of Psychopathology in Association with Childhood Maltreatment -- 3.1 Childhood Maltreatment and Dimensions of Psychopathology in Bipolar Disorders -- 3.2 Childhood Maltreatment and Cognition in Bipolar Disorders -- 4 Childhood Maltreatment as Part of a Multiple Hit Model of Susceptibility. 4.1 Interactions Between Childhood Maltreatment and the Genetic Susceptibility to Bipolar Disorders. |
| Record Nr. | UNINA-9910485147503321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neurochemistry of consciousness [[electronic resource] ] : neurotransmitters in mind / / edited by Elaine Perry, Heather Ashton, and Allan Young ; with a foreword by Susan Greenfield
| Neurochemistry of consciousness [[electronic resource] ] : neurotransmitters in mind / / edited by Elaine Perry, Heather Ashton, and Allan Young ; with a foreword by Susan Greenfield |
| Pubbl/distr/stampa | Amsterdam ; ; Philadelphia, : J. Benjamins Pub. Co., c2002 |
| Descrizione fisica | 1 online resource (356 p.) |
| Disciplina | 153 |
| Altri autori (Persone) |
AshtonHeather
PerryE. K (Elaine K.) YoungA. H (Allan H.) |
| Collana | Advances in consciousness research |
| Soggetto topico |
Consciousness
Neurobehavioral disorders Neurochemistry Neurotransmitters |
| Soggetto genere / forma | Electronic books. |
| ISBN |
9786612255045
1-282-25504-5 90-272-9789-4 0-585-46125-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Neurochemistry of Consciousness; Editorial page; Title page; LCC Data; Table of contents; Foreword; Preface; Part I: Neurotransmitter Systems; Chapter 1: Neurotransmitter networks; Chapter 2: Cholinergic transmission; Part II: Natural Alterations of Consciousness; Chapter 3: Attention; Chapter 4: Memory; Chapter 5: Motivation; Chapter 6: Sleep; Chapter 7: Dreaming; Chapter 8: Dreaming; Part III: Drug-Induced Alterations in Consciousness; Chapter 9: General anesthetics; Chapter 10: Effects of drugs on sleep; Chapter 11: Neuroleptics; Chapter 12: Delirium and hallucinations
Chapter 13: Plants of the godsPart IV: Brain Pathology and Consciousness; Chapter 14: Alzheimer's disease; Chapter 15: Parkinson's disease; Chapter 16: Dementia with Lewy bodies; Chapter 17: Schizophrenia; Chapter 18: Mood disorders; Chapter 19: Mental retardation and autism; Envoi; Index |
| Record Nr. | UNINA-9910450047103321 |
| Amsterdam ; ; Philadelphia, : J. Benjamins Pub. Co., c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neurochemistry of consciousness [[electronic resource] ] : neurotransmitters in mind / / edited by Elaine Perry, Heather Ashton, and Allan Young ; with a foreword by Susan Greenfield
| Neurochemistry of consciousness [[electronic resource] ] : neurotransmitters in mind / / edited by Elaine Perry, Heather Ashton, and Allan Young ; with a foreword by Susan Greenfield |
| Pubbl/distr/stampa | Amsterdam ; ; Philadelphia, : J. Benjamins Pub. Co., c2002 |
| Descrizione fisica | 1 online resource (356 p.) |
| Disciplina | 153 |
| Altri autori (Persone) |
AshtonHeather
PerryE. K (Elaine K.) YoungA. H (Allan H.) |
| Collana | Advances in consciousness research |
| Soggetto topico |
Consciousness
Neurobehavioral disorders Neurochemistry Neurotransmitters |
| ISBN |
9786612255045
1-282-25504-5 90-272-9789-4 0-585-46125-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Neurochemistry of Consciousness; Editorial page; Title page; LCC Data; Table of contents; Foreword; Preface; Part I: Neurotransmitter Systems; Chapter 1: Neurotransmitter networks; Chapter 2: Cholinergic transmission; Part II: Natural Alterations of Consciousness; Chapter 3: Attention; Chapter 4: Memory; Chapter 5: Motivation; Chapter 6: Sleep; Chapter 7: Dreaming; Chapter 8: Dreaming; Part III: Drug-Induced Alterations in Consciousness; Chapter 9: General anesthetics; Chapter 10: Effects of drugs on sleep; Chapter 11: Neuroleptics; Chapter 12: Delirium and hallucinations
Chapter 13: Plants of the godsPart IV: Brain Pathology and Consciousness; Chapter 14: Alzheimer's disease; Chapter 15: Parkinson's disease; Chapter 16: Dementia with Lewy bodies; Chapter 17: Schizophrenia; Chapter 18: Mood disorders; Chapter 19: Mental retardation and autism; Envoi; Index |
| Record Nr. | UNINA-9910782958403321 |
| Amsterdam ; ; Philadelphia, : J. Benjamins Pub. Co., c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neurochemistry of consciousness [[electronic resource] ] : neurotransmitters in mind / / edited by Elaine Perry, Heather Ashton, and Allan Young ; with a foreword by Susan Greenfield
| Neurochemistry of consciousness [[electronic resource] ] : neurotransmitters in mind / / edited by Elaine Perry, Heather Ashton, and Allan Young ; with a foreword by Susan Greenfield |
| Pubbl/distr/stampa | Amsterdam ; ; Philadelphia, : J. Benjamins Pub. Co., c2002 |
| Descrizione fisica | 1 online resource (356 p.) |
| Disciplina | 153 |
| Altri autori (Persone) |
AshtonHeather
PerryE. K (Elaine K.) YoungA. H (Allan H.) |
| Collana | Advances in consciousness research |
| Soggetto topico |
Consciousness
Neurobehavioral disorders Neurochemistry Neurotransmitters |
| ISBN |
9786612255045
1-282-25504-5 90-272-9789-4 0-585-46125-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Neurochemistry of Consciousness; Editorial page; Title page; LCC Data; Table of contents; Foreword; Preface; Part I: Neurotransmitter Systems; Chapter 1: Neurotransmitter networks; Chapter 2: Cholinergic transmission; Part II: Natural Alterations of Consciousness; Chapter 3: Attention; Chapter 4: Memory; Chapter 5: Motivation; Chapter 6: Sleep; Chapter 7: Dreaming; Chapter 8: Dreaming; Part III: Drug-Induced Alterations in Consciousness; Chapter 9: General anesthetics; Chapter 10: Effects of drugs on sleep; Chapter 11: Neuroleptics; Chapter 12: Delirium and hallucinations
Chapter 13: Plants of the godsPart IV: Brain Pathology and Consciousness; Chapter 14: Alzheimer's disease; Chapter 15: Parkinson's disease; Chapter 16: Dementia with Lewy bodies; Chapter 17: Schizophrenia; Chapter 18: Mood disorders; Chapter 19: Mental retardation and autism; Envoi; Index |
| Record Nr. | UNINA-9910826192303321 |
| Amsterdam ; ; Philadelphia, : J. Benjamins Pub. Co., c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Price measurements and their uses [[electronic resource] /] / edited by Murray F. Foss, Marilyn E. Manser, Allan H. Young
| Price measurements and their uses [[electronic resource] /] / edited by Murray F. Foss, Marilyn E. Manser, Allan H. Young |
| Pubbl/distr/stampa | Chicago, : University of Chicago Press, c1993 |
| Descrizione fisica | 1 online resource (404 p.) |
| Disciplina | 338.5/28 |
| Altri autori (Persone) |
FossMurray F
ManserMarilyn YoungA. H (Allan H.) |
| Collana | Studies in income and wealth |
| Soggetto topico |
Computers - Prices
Consumer price indexes Price indexes Semiconductors - Prices |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-22340-9
9786611223403 0-226-25732-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Prefatory Note -- Introduction -- 1. Constant-Quality Price Change, Depreciation, and Retirement of Mainframe Computers -- 2. Price Indexes for Microcomputers: An Exploratory Study -- 3. Sources of Price Decline in Computer Processors: Selected Electronic Components -- 4. Cost Function Estimation of Quality Change in Semiconductors -- 5. Measurement of DRAM Prices: Technology and Market Structure -- 6. Adjusting Apparel Indexes in the Consumer Price Index for Quality Differences -- 7. The Effect of Outlet Price Differentials on the U.S. Consumer Price Index -- 8. The Problem of List Prices in the Producer Price Index: The Steel Mill Products Case -- 9. Does Government Regulation Inhibit the Reporting of Transactions Prices by Business? -- 10. The Deflation of Military Aircraft -- 11. Panel Discussion: Implications of BEA's Treatment of Computer Prices and Productivity Measurement -- Contributors -- Author Index -- Subject Index |
| Record Nr. | UNINA-9910451317703321 |
| Chicago, : University of Chicago Press, c1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Price measurements and their uses [[electronic resource] /] / edited by Murray F. Foss, Marilyn E. Manser, Allan H. Young
| Price measurements and their uses [[electronic resource] /] / edited by Murray F. Foss, Marilyn E. Manser, Allan H. Young |
| Pubbl/distr/stampa | Chicago, : University of Chicago Press, c1993 |
| Descrizione fisica | 1 online resource (404 p.) |
| Disciplina | 338.5/28 |
| Altri autori (Persone) |
FossMurray F
ManserMarilyn YoungA. H (Allan H.) |
| Collana | Studies in income and wealth |
| Soggetto topico |
Computers - Prices
Consumer price indexes Price indexes Semiconductors - Prices |
| Soggetto non controllato | economy, technology, goods, services, business organization, price change, output, productivity, living standards, high-tech products, semiconductors, personal computers, mainframe, retirement, depreciation, apparel, aircraft, military, regulation, government, trade, international, defense, nonfiction, economics, list prices |
| ISBN |
1-281-22340-9
9786611223403 0-226-25732-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Prefatory Note -- Introduction -- 1. Constant-Quality Price Change, Depreciation, and Retirement of Mainframe Computers -- 2. Price Indexes for Microcomputers: An Exploratory Study -- 3. Sources of Price Decline in Computer Processors: Selected Electronic Components -- 4. Cost Function Estimation of Quality Change in Semiconductors -- 5. Measurement of DRAM Prices: Technology and Market Structure -- 6. Adjusting Apparel Indexes in the Consumer Price Index for Quality Differences -- 7. The Effect of Outlet Price Differentials on the U.S. Consumer Price Index -- 8. The Problem of List Prices in the Producer Price Index: The Steel Mill Products Case -- 9. Does Government Regulation Inhibit the Reporting of Transactions Prices by Business? -- 10. The Deflation of Military Aircraft -- 11. Panel Discussion: Implications of BEA's Treatment of Computer Prices and Productivity Measurement -- Contributors -- Author Index -- Subject Index |
| Record Nr. | UNINA-9910785000203321 |
| Chicago, : University of Chicago Press, c1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||