Etiology and Morphogenesis of Congenital Heart Disease [[electronic resource] ] : From Gene Function and Cellular Interaction to Morphology / / edited by Toshio Nakanishi, Roger R. Markwald, H.Scott Baldwin, Bradley B. Keller, Deepak Srivastava, Hiroyuki Yamagishi |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (XII, 383 p. 109 illus., 99 illus. in color.) |
Disciplina | 616.12 |
Soggetto topico |
Cardiology
Pediatric surgery Embryology Pediatrics Pediatric Surgery |
ISBN | 4-431-54628-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I. From Molecular Mechanism to Intervention for Congenital Heart Diseases, Now and Future -- Reprogramming Approaches to Cardiovascular Disease: From Developmental Biology to Regenerative Medicine -- The arterial epicardium, a developmental approach to cardiac disease and repair -- Cell sheet tissue engineering for heart failure -- Future treatment of heart failure and pathophysiological analysis of various heart diseases using human iPS cell-derived cardiomyocytes -- Congenital heart disease: in search of remedial etiologies -- Part II. Left-Right Axis and Heterotaxy Syndrome -- Left-right Asymmetry and Human Heterotaxy Syndrome -- Roles of motile and immotile cilia in left-right symmetry breaking -- Role of cilia and left-right patterning in congenital heart disease -- Pulmonary arterial hypertension in patients with heterotaxy /polysplenia syndrome -- Part III. Cardiomyocyte and Myocardial Development -- Single Cell Expression Analyses of Embryonic Cardiac Progenitor Cells -- Meis1 Regulates Post-Natal Cardiomyocyte Cell Cycle Arrest -- Intercellular signalling in cardiac development and disease: NOTCH -- The epicardium in ventricular septation during evolution and development -- S1P-S1p2 signaling in cardiac precursor cells migration -- Myogenic progenitor cell differentiation is dependent on modulation of mitochondrial biogenesis through autophagy -- The role of the thyroid in the developing heart -- Part IV. Valve Development and Diseases -- Atrioventricular valve abnormalities: From molecular mechanisms underlying morphogenesis to clinical perspective -- Molecular Mechanisms of Heart Valve Development and Disease -- A novel role for endocardium in perinatal valve development: Lessons learned from tissue specific gene deletion of the Tie1 receptor tyrosine kinase -- The Role of the Epicardium in the Formation of the Cardiac Valves in the Mouse -- TMEM100, a novel intracellular transmembrane protein essential for vascular development and cardiac morphogenesis -- Cell autonomous regulation of BMP-2 in endocardial cushion cells during AV valvuloseptal morphogenesis -- Part V. The Second Heart Field and Outflow Tract -- Properties of cardiac progenitor cells in the second heart field -- Nodal signaling and congenital heart defects -- Utilizing Zebrafish to Understand Second Heart Field Development -- A history and interaction of outflow progenitor cells implicated in “Takao syndrome” -- The loss of Foxc2 expression in the outflow tract links the interrupted arch in the conditional Foxc2 knockout mouse -- Environmental modification for phenotype of truncus arteriosus in Tbx1 hypomorphic mice -- Part VI. Vascular Development and Diseases -- Extracellular matrix remodeling in vascular development and disease -- The “cardiac neural crest” concept revisited -- Roles of endothelial Hrt genes for vascular development -- Placental Expression of Type 1 and 3 Inositol Trisphosphate Receptors is Required for the Extra-embryonic Vascular Development -- Tissue Remodeling in Vascular Wall in Kawasaki Disease-related Vasculitis Model Mice -- Part VII. Ductus Arteriosus -- Progerin expression during normal closure of the human ductus arteriosus: A case of premature ageing? -- The multiple roles of prostaglandin E2 in the regulation of the ductus arteriosus -- Developmental Differences in the Maturation of Sarcoplasmic Reticulum and Contractile Proteins in Large Blood Vessels Influences Their Contractility -- Fetal and Neonatal Ductus Arteriosus is Regulated with ATP-sensitive Potassium Channel -- Part VIII. Conduction System and Arrhythmia -- Regulation of vertebrate conduction system development -- Cardiac Pacemaker Development from a Tertiary Heart Field -- Endothelin receptor type A expressing cell population in the inflow tract contributes to chamber formation -- Specific isolation of HCN4 positive cardiac pace-making cells derived from embryonic stem cell -- Part IX. Current Molecular Mechanism in Cardiovascular Development -- Combinatorial functions of transcription factors and epigenetic factors in heart development and disease -- Pcgf5 contributes to PRC1 (Polycomb repressive complex 1) in developing cardiac cells -- non-coding RNAs in cardiovascular disease -- Part X. iPS Cells and Regeneration in Congenital Heart Diseases -- Human pluripotent stem cells to model congenital heart disease -- Engineered cardiac tissues generated from immature cardiac and stem-cell derived cells: Multiple approaches and outcomes -- Dissecting the left heart hypoplasia by pluripotent stem cells -- Lentiviral gene transfer to iPS cells; toward the cardiomyocyte differentiation of Pompe disease-specific iPS cells -- Molecular analysis of long-term cultured cardiac stem cells for cardiac regeneration -- Epicardial contribution in neonatal heart regeneration -- Part XI. Current Genetics in Congenital Heart Diseases -- Genetic discovery for congenital heart defects -- Evidence that deletion of ETS-1, a gene in the Jacobsen syndrome (11q-) cardiac critical region, causes congenital heart defects through impaired cardiac neural crest cell function -- Notch signaling in aortic valve development and disease -- To detect and explore mechanism of CITED2 mutation and methylation in children with congenital heart disease. |
Record Nr. | UNINA-9910161652703321 |
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension / / edited by Toshio Nakanishi, H. Scott Baldwin, Jeffrey R. Fineman, Hiroyuki Yamagishi |
Autore | Nakanishi Toshio |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Singapore, : Springer Nature, 2020 |
Descrizione fisica | 1 online resource (XIII, 406 p. 84 illus., 74 illus. in color.) |
Disciplina | 616.12 |
Soggetto topico |
Cardiology
Pediatrics |
Soggetto non controllato |
Cardiology
Pediatrics Internal Medicine Pulmonary circulation Ductus arteriosus Molecular mechanisms Cellular interactions Stem cell engineering Heart Lung Open access Cardiovascular medicine Paediatric medicine |
ISBN | 981-15-1185-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | PART I: Basic Science of Pulmonary Development and Pulmonary Arterial Disease -- 1 Perspective for Part I -- 2 The alveolar stem cell niche of the mammalian lung -- 3 Lung development and Notch signalling -- 4 Specialized smooth muscle cell progenitors in pulmonary hypertension -- 5 Diverse Pharmacology of Prostacyclin Mimetics: Implications for Pulmonary Hypertension -- 6 Endothelial-to-mesenchymal transition in pulmonary hypertension -- 7 Extracellular vesicles, MicroRNAs and Pulmonary Hypertension -- 8 Roles of Tbx4 in the lung mesenchyme for airway and vascular development -- 9 A lacZ reporter transgenic mouse line revealing the development of pulmonary artery -- 10 Roles of stem cell antigen-1 in the pulmonary endothelium -- 11 Morphological characterization of pulmonary microvascular disease in bronchopulmonary dysplasia caused by hyperoxia in newborn mice -- 12 Involvement of CXCR4 and stem cells in a rat model of pulmonary arterial hypertension -- 13 Ca2+ signal through inositol trisphosphate receptors for cardiovascular development and pathophysiology of pulmonary arterial hypertension -- PART II: Abnormal pulmonary circulation in the developing lung and heart -- 14 Perspective for Part II -- 15 Pathophysiology of Pulmonary Circulation in Congenital Heart Disease -- 16 Development of Novel Therapies for Pulmonary Hypertension by Clinical Application of Basic Research -- 17 Using Patient-Specific Induced Pluripotent Stem Cells to Understand and Treat Pulmonary Arterial Hypertension -- 18 Modeling pulmonary arterial hypertension using induced pluripotent stem cells -- 19 Dysfunction and restoration of endothelial cell communications in Pulmonary Arterial Hypertension: Therapeutic implications -- 20 Inflammatory Cytokines in the Pathogenesis of Pulmonary Arterial Hypertension -- 21 Genotypes and Phenotypes of Chinese Pediatric Patients with Idiopathic and Heritable Pulmonary Arterial Hypertension- Experiences from A Single Center -- 22 Fundamental Insight into Pulmonary Vascular Disease : Perspectives from Pediatric PAH in Japan -- 23 Risk stratification in paediatric pulmonary arterial hypertension -- 24 The Adaptive Right Ventricle in Eisenmenger Syndrome: Potential Therapeutic Targets for Pulmonary Hypertension -- 25 Impaired right coronary vasodilator function in pulmonary hypertensive rat assessed by in vivo synchrotron microangiography -- 26 Relationship between mutations in ENG and ALK1 gene and the affected organs in hereditary hemorrhagic telangiectasia -- 27 A genetic analysis for patients with pulmonary arterial hypertension -- 28 Evaluation and visualization of right ventricle using three dimensional echocardiography -- 29 Pulmonary hypertension associated with post-operative Tetralogy of Fallot -- 30 Microscopic Lung Airway Abnormality and Pulmonary Vascular Disease Associated with Congenital Systemic to Pulmonary Shunt -- 31 Respiratory syncytial virus infection in infants with heart and lung diseases -- PART III: Ductus arteriosus: bridge over troubled vessels -- 32 Perspective for Part III -- 33 The ductus arteriosus, a vascular outsider, in relation to the pulmonary circulation -- 34 Molecular, genetic, and pharmacological modulation of the ductus arteriosus: KATP channels as novel drug targets -- 35 New mediators in the biology of the ductus arteriosus: Lessons from the chicken embryo -- 36 Constriction of the Ductus Arteriosus with KATP Channel Inhibitors -- 37 New insights on how to treat patent ductus arteriosus -- 38 Antenatal Administration of Betamethasone Contributes to Intimal thickening of the Ductus Arteriosus -- 39 Prostaglandin E-EP4-mediated fibulin-1 up-regulation plays a role in intimal thickening of the ductus arteriosus -- 40 Transcriptional profiles in the chicken ductus arteriosus during hatching -- 41 Inhibition of Cyclooxygenase Contracts Chicken Ductus Arteriosus -- 42 Prostaglandin E2 receptor EP4 inhibition constricts the rat ductus arteriosus -- 43 Dilatation of the Ductus Arteriosus by Diazoxide in Fetal and Neonatal Rats -- 44 The Effect of Long-term Administration of Plostaglandin E1 on Morphological Changes in Ductus Arteriosus -- 45 Significance of SGK1 as a protein kinase transcriptionally regulated by ALK1 signaling in vascular endothelial cells -- 46 Fabrication of Implantable Human Arterial Graft by Periodic Hydrostatic Pressure -- 47 Optimum preparation of Candida albicans cell wall extra (CAWE) for the mouse model of Kawasaki disease -- PART IV: Development and Regeneration of the Cardiovascular System -- 48 Perspective for Part IV -- 49 Advances in the second heart field -- 50 Novel cardiac progenitors for all components of the heart except for the right ventricle -- 51 Regional and TBX5-dependent gene expression in the atria: Implications for pulmonary vein development and atrial fibrillation -- 52 The Endocardium as a Master Regulator of Ventricular Trabeculation -- 53 The Role of Alternative mRNA Splicing in Heart Development -- 54 Progress in the Generation of Multiple Lineage Human-iPSC-derived 3D Engineered Cardiac Tissues for Cardiac Repair -- 55 Quantification of contractility in stem cell derived cardiomyocytes -- 56 A neurotrophic factor receptor GFRA2, a specific surface antigen for cardiac progenitor cells, regulates the process of myocardial compaction -- 57 Cardiac cell specification and differentiation by the defined factors -- 58 A Temporo-Spatial Regulation of Sema3c is Essential for Interaction of Progenitor Cells during Cardiac Outflow Tract Development -- 59 Spatiotemporally restricted developmental alterations in the anterior and secondary heart fields cause distinct conotruncal heart defects -- 60 Significance of transcription factors in the mechanisms of great artery malformations -- 61 The different c-kit expression in human induced pluripotent stem (iPS) cells between with feeder cells and without feeder cells -- 62 Establishment of induced pluripotent stem cells from immortalized B cell lines and their differentiation into cardiomyocytes -- 63 Establishment of an in vitro LQT3 model, using induced pluripotent stem cells from LQT3 patient-derived cardiomyocytes -- 64 Genetic Assessments for clinical courses of Left ventricle noncompaction -- 65 Elucidating the pathogenesis of congenital heart disease in the era of next-generation sequencing. |
Record Nr. | UNINA-9910380729503321 |
Nakanishi Toshio
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Singapore, : Springer Nature, 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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