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Skin Stress Response Pathways [[electronic resource] ] : Environmental Factors and Molecular Opportunities / / edited by Georg T. Wondrak
| Skin Stress Response Pathways [[electronic resource] ] : Environmental Factors and Molecular Opportunities / / edited by Georg T. Wondrak |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (IX, 457 p. 68 illus., 39 illus. in color.) |
| Disciplina | 610 |
| Soggetto topico |
Medicine
Biomedicine, general |
| ISBN | 3-319-43157-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- The skin lipidome under environmental stress – Technological platforms, molecular pathways and translational opportunities -- Squalene and skin barrier function: From molecular target to biomarker of environmental exposure -- Sunlight-induced DNA damage: molecular mechanisms and photoprotection strategies -- Urocanic Acid and Skin Photodamage: New Light on an Old Chromophore -- The Skin Extracellular Matrix as a Target of Environmental Exposure: Molecular Mechanisms, Prevention and Repair -- Nitric Oxide Derivatives and Skin Environmental Exposure to light: From Molecular Pathways to Therapeutic Opportunities -- Melanocortin 1 receptor (MC1R) as a global regulator of cutaneous UV responses: molecular interactions and opportunities for melanoma prevention -- The Cutaneous Melanocyte as a Target of Environmental Stressors: Molecular Mechanisms and Opportunities -- The Role of Epidermal p38 Signaling in Solar UV Radiation-induced Inflammation: Molecular Pathways and Preventive Opportunities -- UV-Induced Chemokines as Emerging Targets for Skin Cancer Photochemoprevention -- TLR3 and Inflammatory Skin Diseases: From Environmental Factors to Molecular Opportunities -- Sirtuins and stress response in skin cancer, aging, and barrier function -- Cutaneous Opioid Receptors and Stress Responses: Molecular Interactions and Opportunities for Therapeutic Intervention -- Regulation of Cutaneous Stress Response Pathways by the Circadian Clock: From Molecular Pathways to Therapeutic Opportunities -- Endocannabinoids and Skin Barrier Function: Molecular Pathways and Therapeutic Opportunities -- The aryl hydrocarbon receptor (AhR) as an environmental stress sensor and regulator of skin barrier function: Molecular mechanisms and therapeutic opportunities -- Biological cell protection by natural compounds, a second line of defense against solar radiation -- The Cutaneous Microbiota as a Determinant of Skin Barrier Function: Molecular Interactions and Therapeutic Opportunities -- Sensing Environmental Factors: The Emerging Role of Receptors in Epidermal Homeostasis and Whole-Body Health -- The Cutaneous Circadian Clock as a Determinant of Environmental Vulnerability: Molecular Pathways and Chrono-pharmacological Opportunities -- Psychological stress as a determinant of skin barrier function: Immunological pathways and therapeutic opportunities -- Index. |
| Record Nr. | UNINA-9910253892103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stress Response Pathways in Cancer [[electronic resource] ] : From Molecular Targets to Novel Therapeutics / / edited by Georg T. Wondrak
| Stress Response Pathways in Cancer [[electronic resource] ] : From Molecular Targets to Novel Therapeutics / / edited by Georg T. Wondrak |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (450 p.) |
| Disciplina |
571.6
610 614.5999 616994 |
| Soggetto topico |
Cancer research
Cell biology Oncology Cancer Research Cell Biology Oncology |
| ISBN | 94-017-9421-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Introduction to cell stress responses in cancer: The big picture -- DNA repair dysregulation in cancer: From molecular mechanisms to synthetic-lethal opportunities -- Cell cycle checkpoint defects as anticancer targets: From molecular mechanisms to therapeutic opportunities -- p53 at the crossroads between stress response signaling and tumorigenesis: From molecular mechanisms to therapeutic opportunities -- Sirtuins as a double-edged sword in cancer: From molecular mechanisms to therapeutic opportunities -- MicroRNA regulated stress responses in cancer -- Senescence in oncogenesis: From molecular mechanisms to therapeutic opportunities -- Pro-senescence therapy for cancer: time for the clinic -- Integrating proteotoxic stress response pathways for induction of cell death in cancer cells: molecular mechanisms and opportunities -- The Hsp70 family of heat shock proteins in tumorigenesis: From molecular mechanisms to therapeutic opportunities -- The ubiquitin-proteasome system (UPS) as a cancer drug target: Emerging mechanisms and therapeutics -- Endoplasmatic reticulum stress in multiple myeloma: From molecular mechanisms to therapeutic opportunities -- Melanomagenic gene alterations viewed from a redox perspective: Molecular mechanisms and therapeutic opportunities -- Targeting hypoxic adaptations of cancer cells: Molecular mechanisms and therapeutic opportunities -- Targeting glycolytic adaptations of cancer cells: from molecular mechanisms to therapeutic opportunities -- At the crossroads between mitochondrial metabolite transport and apoptosis: VDAC1 as an emerging cancer drug target -- Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities -- Cell-nonautonomous ER stress-mediated dysregulation of immunity by cancer cells -- Index. |
| Record Nr. | UNINA-9910298284303321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||