Pubbl/distr/stampa	Chichester ; ; New York, : Wiley, 1992
Descrizione fisica	1 online resource (286 p.)
Disciplina	574.19 574.87 574.876041
Altri autori (Persone)	SatōRyō <1923-1996.> BockGregory WiddowsKate
Collana	Ciba Foundation symposium
Soggetto topico	Cellular signal transduction Cell interaction
Soggetto genere / forma	Electronic books.
ISBN	1-282-34776-4 9786612347764 0-470-51420-5 0-470-51421-3
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	INTERACTIONS AMONG CELL SIGNALLING SYSTEMS; Contents; Introduction; lnositol lipids and phosphates in the proliferation and differentiation of lymphocytes and myeloid cells; The inositol 1,4,5-trisphosphate receptor; Regulation of phosphoinositide and phosphatidylcholine phospholipases by G proteins; The signal-induced phospholipid degradation cascade and protein kinase C activation; The acetylcholine receptor: a model of an allosteric rnern brane protein mediating intercellular cornmunication; Ca2+-cyclic AMP interactions in sustained cellular responses Growth factor-stimulated phosphorylation cascades: activation of growth factor-stimulated MAP kinaseTyrosine phosphatases and their possible interplay with tyrosine kinases; Calmodulin and protein kinase C cross-talk: the MARCKS protein is an actin filament and plasma membrane cross-linking protein regulated by protein kinase C phosphorylation and by calmodulin; The synaptic activation of NMDA receptors and Ca2+ signalling in neurons; Persistent signalling and changes in presynaptic function in long-term potentiation; General discussion I The metabotropic glutamate receptor Distribution of protein kinase C subspecies in the hippocampal formationCross-talk between the phosphatidylinositol and adenylate cyclase signalling systems; T lymphocyte activation signals; Growth factor phosphorylation of C-y1; Protein tyrosine kinases belonging to the src family; General discussion II; Index of contributors; Subject index
Record Nr.	UNINA-9910144012203321

Pubbl/distr/stampa	Chichester [England] ; ; New York, : Wiley, 1990
Descrizione fisica	1 online resource (268 p.)
Disciplina	612.7/55 617.755
Altri autori (Persone)	BockGregory WiddowsKate
Collana	Ciba Foundation symposium
Soggetto topico	Myopia Eye - Growth - Regulation
Soggetto genere / forma	Electronic books.
ISBN	1-282-45540-0 9786612455407 0-470-51402-7 0-470-51403-5
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	MYOPIA AND THE CONTROL OF EYE GROWTH; Contents; Introduction; Pathways mediating resolution in the primate retina; Neural control of eye growth and experimental myopia in primates; Postnatal control of ocular growth: dopaminergic mechanisms; Effects of selective neurotoxins on eye growth in the young chick; Experimental studies of emmetropization in the chick; Emmetropization in the primate eye; Retinal influences on sclera underlie visual deprivation myopia; General discussion I : Stretch or growth?; Emmetropization or normal growth? Avian models of experimental myopia: environmental factors in the regulation of eye growth Optical causes of experimental myopia; Experimental myopia in tree shrews; General discussion II : Effect of ablation of the fundus; What are the signals for defocus?; Light rhythm and eye growth; Effects of zinc and copper metabolism in highly myopic patients; Myopia in humans: can progression be arrested?; Final general discussion : Axial or equatorial enlargement?; Future studies; Summing-up; Index of contributors; Subject index
Record Nr.	UNINA-9910144744903321

Pubbl/distr/stampa	Chichester, England ; ; New York, N.Y., : Wiley, 1992
Descrizione fisica	1 online resource (292 p.)
Disciplina	574.8 616.07 616.079
Altri autori (Persone)	BockGregory MarshJoan WiddowsKate
Collana	Ciba Foundation symposium
Soggetto topico	Interleukin-6 Leukemia inhibitory factor
ISBN	1-282-34779-9 9786612347795 0-470-51426-4 0-470-51427-2
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	POLYFUNCTIONAL CYTOKINES: IL-6 AND LIF; Contents; Introduction; The molecular biology of interleukin 6 and its receptor; Molecular biology of the leukemia inhibitory factor gene; Regulation of expression of the interleukin 6 gene: structure and function of the transcription factor NF-IL6; The action of interleukin 6 on lymphoid populations; Regulation of leukemic cells by interleukin 6 and leukemia inhibitory factor; The action of interleukin 6 and leukemia inhibitory factor on liver cells; Further studies of the distribution of CDF/LIF mRNA Leukemia inhibitory factor and bone cell function General discussion I : Acute-phase responses; The role of interleukin 6 in megakaryocyte formation, megakaryocyte development and platelet production; Actions of leukemia inhibitory factor on megakaryocyte and platelet formation; The role of interleukin 6 in plasmacytomagenesis; General discussion II : Interleukin 6, leukemia inhibitory factor and granulocyte colony-stimulating factor; The effects of leukemia inhibitory factor and interleukin 6 on vascular function Interleukin 6 determination in the detection of microbial invasion of the amniotic cavity General discussion III : The multimeric nature of human interleukin 6; Distribution and binding properties of receptors for leukemia inhibitory factor; Reconstitution of high affinity leukemia inhibitory factor (LIF) receptors in haemopoietic cells transfected with the cloned human LIF receptor; General discussion IV : Cytokines and binding proteins in the circulation; The role of leukemia inhibitory factor and interleukin 6 in tumorigenesis; Summing-up; Index of contributors; Subject index
Record Nr.	UNINA-9910829887403321

Pubbl/distr/stampa	Chichester, West Sussex, England ; ; New York, : Wiley, 1990
Descrizione fisica	1 online resource (296 p.)
Disciplina	612.8 612.814
Altri autori (Persone)	ChadwickDerek WiddowsKate
Collana	Ciba Foundation symposium
Soggetto topico	Neuroendocrinology Steroid hormones - Physiological effect Neurons
Soggetto genere / forma	Electronic books.
ISBN	1-282-34767-5 9786612347672 0-470-51398-5 0-470-51399-3
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	STEROIDS AND NEURONAL ACTIVITY; Contents; Introduction; Steroid effects on neuronal activity: when is the genome involved?; Neuroendocrine metabolism of progesterone and related progestins; Steroid modulation of the GABAA receptor complex: electrophysiological studies; Steroid regulation of the GABAA receptor: ligand binding, chloride transport and behaviour; Steroid binding at si receptors: CNS and immunological implications; General discussion I : Gene-mediated corticosteroid effects on neuronal excitability; Effects of progesterone and its metabolites on neuronal membranes In vitro effects of 17B-oestradiol on the sensitivity of receptors coupled to adenylate cyclase on striatal neurons in primary cultureEffect of oestradiol on dopamine receptors and protein kinase C activity in the rat pituitary: binding of oestradiol to pituitary membranes; The molecular features of membrane perturbation by anaesthetic steroids: a study using differential scanning calorimetry, small angle X-ray diffraction and solid state 2H NMR; Effects of prostaglandin E2 and progesterone on rat brain synaptosomal plasma membranes; Steroids and neuronal destruction or stabilization General discussion II : Sex differences in GABA-mediated responsesSteroids in relation to epilepsy and anaesthesia; Early and late effects of steroid hormones on the central nervous system; Final general discussion : Use of adrenal corticosteroids in sports; Steroids and anaesthesia; Role of steroids in the brain; Genomic or non-genomic?; Summing-up; Index of contributors; Subject index
Record Nr.	UNINA-9910144745503321