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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
peroxisome-proliferator activated receptors
tumor angiogenesis tumor progression metastasis formation endothelial cells RNA sequencing PPARs toxicology pharmacology ligand vascular coronary artery lipidomics eicosanoids inflammation CYP450 peroxisome proliferator-activated receptor angiogenesis proliferation metastasis immortality resistance to cell death growth suppressors immune system cellular metabolism PPAR nuclear receptors addiction alcohol nicotine opioids psychostimulants animal models human studies Alzheimer’s risk factors PPARα lipids fatty acids modulators cognition sex therapy hypertrophic adipocytes PPARG isoforms PPARG splicing dominant-negative isoform in vitro adipocytes adipogenesis hypertrophic obesity insulin-resistance peroxisome proliferator-activated receptors (PPARs) synthetic agonists non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) fibrosis Sirtuin1 peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator activated receptors obesity metabolic syndrome vitamin B12 folate fetal programming inherited metabolic disorders PGC-1α, disease kidney cancer AKI CKD nephron PKD cilia cystogenesis ligands Alzheimer’s disease (AD) |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptional Regulation of Cardiac Development and Disease
| Transcriptional Regulation of Cardiac Development and Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
pluripotent stem cells
cardiomyocytes cardiac tissue engineering human heart tissue maturation Wilms' tumor suppressor 1 cardiomyocyte differentiation mouse embryonic stem cells myocardial infarction YAP TEAD1 Toll-like receptor heart TLR4 cardiomyocyte innate immune responses Wilms' tumor suppressor 1 (Wt1) cardiac development coronary vessel formation transcriptional regulation cardiac malformation epicardium epicardial derived cells (EPDCs) epithelial mesenchymal transition (EMT) cardiac cell fate regeneration arrhythmogenic cardiomyopathy (ACM) lamin A/C atomic force microscopy (AFM) cell-cell adhesion neonatal rat ventricular fibroblasts (NRVF) tunneling nanotubes (TNT) gene therapy cardiovascular diseases cardiac regeneration cardiac reprogramming therapeutic angiogenesis growth factors reactive oxygen species apoptosis Bmp signaling Hand1 Smad heart development SH3BGR cardiac hypertrophy SRF signaling Hippo signaling cardiomyogenic differentiation cardiac mesenchymal stromal cell hydrogels histone deacetylase inhibitors translational studies gene expression and regulation cardiomyopathy heart failure reverse remodelling left ventricular assist device |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674017103321 |
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Wagner Nicole
|
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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