Molecular basis of oxidative stress [[electronic resource] ] : chemistry, mechanisms, and disease pathogenesis / / edited by Frederick A. Villamena |
Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2013 |
Descrizione fisica | 1 online resource (448 p.) |
Disciplina | 571.9/453 |
Altri autori (Persone) | VillamenaFrederick A |
Soggetto topico |
Oxidative stress
Oxidation |
ISBN |
1-118-35587-3
1-118-35588-1 1-118-35586-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Title page; Copyright page; Contents; Preface; About the Contributors; Contributors; 1: Chemistry of Reactive Species; 1.1 Redox Chemistry; 1.2 Classification of Reactive Species; 1.2.1 Type of Orbitals; 1.2.2 Stability of Radicals; 1.2.3 ROS; 1.2.4 Reactive Nitrogen Species; 1.2.5 Reactive Sulfur and Chlorine Species; 1.3 Reactivity; 1.3.1 Thermodynamic Considerations; 1.3.2 Kinetic Considerations; 1.4 Origins of Reactive Species; 1.4.1 Biological Sources; 1.4.2 Nonbiochemical Sources; 1.5 Methods of Detection; 1.5.1 In Vitro; 1.5.2 In Vivo; References
2: Lipid Peroxidation and NitrationOverview; 2.1 Peroxidation of PUFAs; 2.1.1 Hydroperoxy Fatty Acid Isomers (HpETEs and HpODEs); 2.1.2 Hydroxy Fatty Acids (HETEs and HODEs); 2.1.3 Isoleukotrienes; 2.1.4 Epoxy Alcohols; 2.2 Cyclic Endoperoxides and Their Products; 2.2.1 Isoprostanes; 2.2.2 Diepoxide Pathway Products; 2.2.3 Serial Cyclic Endoperoxides; 2.3 Fragmented Products of Lipid Peroxidation; 2.3.1 Short-Chain Alkanes, Aldehydes, and Acids; 2.3.2 Oxidatively Fragmented Phospholipids; 2.3.3 PAF Acetylhydrolase; 2.3.4 Hydroxyalkenals; 2.3.5 Malondialdehyde; 2.3.6 Acrolein 2.4 Epoxy Fatty Acids2.5 Lipid Nitrosylation; 2.5.1 Formation of Reactive Nitrogen Species; 2.5.2 Lipid Nitration Reactions; 2.5.3 Detection of Lipid Nitration In Vivo; 2.5.4 Bioactivities of Nitrated Lipids; Summary; References; 3: Protein Posttranslational Modification; Overview; 3.1 Oxidative Stress-Related PTMs: Oxidation Reactions; 3.1.1 Cysteine; 3.1.2 Methionine; 3.1.3 Oxidation of Aromatic Amino Acids; 3.1.4 Oxidation of Aliphatic Amino Acids; 3.2 Amino Acid Modification by Oxidation-Produced Electrophiles; 3.2.1 Electrophiles Formed by Oxidative Stress 4.3.3 Novel Types of Ribose and Guanine Oxidative Lesions and Future OutlookFuture Outlook of DNA Oxidative Lesions; References; 5: Downregulation of Antioxidants and Phase 2 Proteins; Overview; 5.1 Definitions of Antioxidants and Phase 2 Proteins; 5.1.1 Antioxidants; 5.1.2 Phase 2 Proteins; 5.2 Roles in Oxidative Stress; 5.2.1 Superoxide Dismutase; 5.2.2 Catalase; 5.2.3 GSH and GSH-Related Enzymes; 5.2.4 NAD(P)H:Quinone Oxidoreductase; 5.2.5 Heme Oxygenase; 5.2.6 Ferritin; 5.2.7 UDP-Glucuronosyltransferase; 5.3 Molecular Regulation; 5.3.1 General Consideration; 5.3.2 Nrf2 Signaling 5.3.3 Other Regulators |
Record Nr. | UNINA-9910139054303321 |
Hoboken, N.J., : Wiley, c2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Molecular basis of oxidative stress : chemistry, mechanisms, and disease pathogenesis / / edited by Frederick A. Villamena |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2013 |
Descrizione fisica | 1 online resource (448 p.) |
Disciplina | 571.9/453 |
Altri autori (Persone) | VillamenaFrederick A |
Soggetto topico |
Oxidative stress
Oxidation |
ISBN |
1-118-35587-3
1-118-35588-1 1-118-35586-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Title page; Copyright page; Contents; Preface; About the Contributors; Contributors; 1: Chemistry of Reactive Species; 1.1 Redox Chemistry; 1.2 Classification of Reactive Species; 1.2.1 Type of Orbitals; 1.2.2 Stability of Radicals; 1.2.3 ROS; 1.2.4 Reactive Nitrogen Species; 1.2.5 Reactive Sulfur and Chlorine Species; 1.3 Reactivity; 1.3.1 Thermodynamic Considerations; 1.3.2 Kinetic Considerations; 1.4 Origins of Reactive Species; 1.4.1 Biological Sources; 1.4.2 Nonbiochemical Sources; 1.5 Methods of Detection; 1.5.1 In Vitro; 1.5.2 In Vivo; References
2: Lipid Peroxidation and NitrationOverview; 2.1 Peroxidation of PUFAs; 2.1.1 Hydroperoxy Fatty Acid Isomers (HpETEs and HpODEs); 2.1.2 Hydroxy Fatty Acids (HETEs and HODEs); 2.1.3 Isoleukotrienes; 2.1.4 Epoxy Alcohols; 2.2 Cyclic Endoperoxides and Their Products; 2.2.1 Isoprostanes; 2.2.2 Diepoxide Pathway Products; 2.2.3 Serial Cyclic Endoperoxides; 2.3 Fragmented Products of Lipid Peroxidation; 2.3.1 Short-Chain Alkanes, Aldehydes, and Acids; 2.3.2 Oxidatively Fragmented Phospholipids; 2.3.3 PAF Acetylhydrolase; 2.3.4 Hydroxyalkenals; 2.3.5 Malondialdehyde; 2.3.6 Acrolein 2.4 Epoxy Fatty Acids2.5 Lipid Nitrosylation; 2.5.1 Formation of Reactive Nitrogen Species; 2.5.2 Lipid Nitration Reactions; 2.5.3 Detection of Lipid Nitration In Vivo; 2.5.4 Bioactivities of Nitrated Lipids; Summary; References; 3: Protein Posttranslational Modification; Overview; 3.1 Oxidative Stress-Related PTMs: Oxidation Reactions; 3.1.1 Cysteine; 3.1.2 Methionine; 3.1.3 Oxidation of Aromatic Amino Acids; 3.1.4 Oxidation of Aliphatic Amino Acids; 3.2 Amino Acid Modification by Oxidation-Produced Electrophiles; 3.2.1 Electrophiles Formed by Oxidative Stress 4.3.3 Novel Types of Ribose and Guanine Oxidative Lesions and Future OutlookFuture Outlook of DNA Oxidative Lesions; References; 5: Downregulation of Antioxidants and Phase 2 Proteins; Overview; 5.1 Definitions of Antioxidants and Phase 2 Proteins; 5.1.1 Antioxidants; 5.1.2 Phase 2 Proteins; 5.2 Roles in Oxidative Stress; 5.2.1 Superoxide Dismutase; 5.2.2 Catalase; 5.2.3 GSH and GSH-Related Enzymes; 5.2.4 NAD(P)H:Quinone Oxidoreductase; 5.2.5 Heme Oxygenase; 5.2.6 Ferritin; 5.2.7 UDP-Glucuronosyltransferase; 5.3 Molecular Regulation; 5.3.1 General Consideration; 5.3.2 Nrf2 Signaling 5.3.3 Other Regulators |
Record Nr. | UNINA-9910809586703321 |
Hoboken, N.J., : Wiley, c2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|