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Glia in Health and Disease
Glia in Health and Disease
Autore Ho Margaret S
Pubbl/distr/stampa Frontiers Media SA, 2019
Descrizione fisica 1 online resource (385 p.)
Soggetto topico Neurosciences
Science: general issues
Soggetto non controllato ALS
astroglia
Microglia
Myelination
Synaptic Transmission
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557498103321
Ho Margaret S  
Frontiers Media SA, 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain / / edited by Vladimir Parpura, Arne Schousboe, Alexei Verkhratsky
Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain / / edited by Vladimir Parpura, Arne Schousboe, Alexei Verkhratsky
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (275 p.)
Disciplina 572.65
Collana Advances in Neurobiology
Soggetto topico Neurosciences
Neurobiology
ISBN 3-319-08894-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Glutamate and ATP: The Crossroads of Signaling and Metabolism in the Brain -- 2. Glutamate Metabolism in the Brain Focusing on Astrocytes -- 3. Glycogenolysis and Purinergic Signaling -- 4. Purinergic and Glutamatergic Receptors on Astroglia -- 5. Regulated Exocytosis in Astrocytes Is as Slow as the Metabolic Availability of Gliotransmitters: Focus on Glutamate and ATP -- 6. Adenosine and Glutamate in Neuroglial Interaction: Implications for Circadian Disorders and Alcoholism -- 7. Purinergic Receptor Stimulation Decreases Ischemic Brain Damage By Energizing Astrocyte Mitochondria -- 8. Excitotoxicity and Mitochondrial Dysfunction Underlie Age-dependent Ischemic White Matter Injury -- 9. Role of Astrocytes in Delayed Neuronal Death: GLT-1 and its Novel Regulation by MicroRNAs -- 10. Ca2+ Signaling in Astrocytes and its Role in Ischemic Stroke -- 11. Pathological Potential of Astroglial Purinergic Receptors.
Record Nr. UNINA-9910298325303321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Microglia : Physiology, Pathophysiology and Therapeutic Potential / / edited by Marie-Ève Tremblay, Alexei Verkhratsky
Microglia : Physiology, Pathophysiology and Therapeutic Potential / / edited by Marie-Ève Tremblay, Alexei Verkhratsky
Autore Tremblay Marie-Ève
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (635 pages)
Disciplina 616.80471
Altri autori (Persone) VerkhratskyAlexei
Collana Advances in Neurobiology
Soggetto topico Neurosciences
Neurology
Immunology
Neuroscience
ISBN 3-031-55529-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto PART I: Introduction -- Chapter 1: General Pathophysiology of Microglia -- Chapter 2: History of Microglia -- Chapter 3: Evolution of Microglia -- Chapter 4: Visualization, Fate Mapping, Ablation and Mutagenesis of Microglia in the Mouse Brain -- Chapter 5: Technological Innovations: Progress of the Structural and Functional in vivo Imaging of Microglia -- PART II: Basic Discoveries in Physiology -- Chapter 6:Microglial Physiology: Receptors -- Chapter 7: Microglial Physiology: Calcium Signalling -- Chapter 8:Contactomics of Microglia and Intercellular Communication -- Chapter 9: Elimination of Neurones: Embryonic and Postnatal Development -- Chapter 10: Developmental Angiogenesis, Astrogliogenesis, and Myelination -- Chapter 11: Synaptic Formation and Elimination -- Chapter 12: Synaptic Maturation, Activity, and Plasticity -- Chapter 13: Adult Neurogenesis, Learning and Memory -- Chapter 14: Regulation of Sleep and Wakefulness -- PART III: General Pathophysiology of Microglia -- Chapter 15: Roles in Innate Immunity -- Chapter 16: Microglia and Systemic Immunity -- Chapter 17: Microglia and Microbiome-Gut-Brain Axis -- Chapter 18: Stress and Microglia: A Double-Edged Relationship -- Chapter 19: Substance Use and Addiction -- Chapter 20: Microglia and Sleep Disorders -- Chapter 21: Ageing -- Part IV: Microglia and Pathophysiology of Diseases of Nervous System -- Chapter 22: Neuropathic Pain -- Chapter 23: Role of Microglia in Stroke -- Chapter 24: Infectious Diseases including COVID-19 and HAND -- Chapter 25: Microglia and Multiple Sclerosis -- Chapter 26: Neurodevelopmental and Neuropsychiatric Disorders -- Chapter 27: Neurodegenerative Diseases -- Chapter 28: Microglia in Glioma -- PART V: Clinical Potential -- Chapter 29: Microglial Risk Alleles for Neurodegenerative Diseases (GWAS studies) -- Chapter 30: Emerging Models for the Study of Human Microglia in vitro (e.g. IPSCs, minibrains) -- Chapter 31: Emerging Models for the Study of Human Microglia ex vivo (comparison between human and rodent microglia) -- Chapter 32: Radiotracers for Microglial PET Imaging in vivo (focus on TSPO and its limitations) -- Chapter 33: Role of Microglial Modulation in Therapies for Perinatal Brain Injuries Leading to Neurodevelopmental Disorders -- Chapter 34: Metabolic Control of Microglial Function -- Chapter 35: Microglial Emerging Therapies and Targets under Clinical Trial -- Chapter 36: Epilogue.
Record Nr. UNINA-9910886079203321
Tremblay Marie-Ève  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024
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Lo trovi qui: Univ. Federico II
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Neuroglia in Neurodegenerative Diseases / / edited by Alexei Verkhratsky, Margaret S. Ho, Robert Zorec, Vladimir Parpura
Neuroglia in Neurodegenerative Diseases / / edited by Alexei Verkhratsky, Margaret S. Ho, Robert Zorec, Vladimir Parpura
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (x, 405 pages) : illustrations
Disciplina 616.8047
Collana Advances in Experimental Medicine and Biology
Soggetto topico Neurosciences
Neurology
Molecular biology
Molecular Medicine
ISBN 981-13-9913-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction to neuroglia: history, definition, development and main functions -- Evolution of astroglia -- Physiology of astroglia -- Glicoryne system: glial cells as secretory cells of the CNS -- Physiology of oligodendroglia and NG-2 glia -- Physiology of microglia -- General pathophysiology of neuroglia -- Neuroglia in ageing -- In vivo imaging of neuroglia in neurodegenerative diseases -- Astroglia in leukodystrophies -- Astrocytes in ALS -- Astroglia in Alzheimer's disease -- Oligodendrogia in Alzheimer's disease -- Microglia in AD -- Neuroglia in Parkinson's disease -- Neuroglia in Huntington disease -- Neuroglia as a therapeutic target -- Stem cell derived neuroglia: new tool for research and treatment of neurodegenerative diseases.
Record Nr. UNINA-9910350348703321
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Pathological Potential of Neuroglia : Possible New Targets for Medical Intervention / / edited by Vladimir Parpura, Alexei Verkhratsky
Pathological Potential of Neuroglia : Possible New Targets for Medical Intervention / / edited by Vladimir Parpura, Alexei Verkhratsky
Edizione [1st ed. 2014.]
Pubbl/distr/stampa New York, NY : , : Springer New York : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (546 p.)
Disciplina 610
612.8
612.8042
616.8
Soggetto topico Neurosciences
Neurochemistry
Neurology
Psychiatry
ISBN 1-4939-0974-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto General Pathophysiology of Neuroglia: Neurological and Psychiatric Disorders as Gliopathies -- Ionic Signaling in Physiology and Pathophysiology of Astroglia -- Pathophysiology of Vesicle Dynamics in Astrocytes -- Glial Glutamate and Metabolic Transporters as a Target for Neurodegenerative Therapy and Biomarkers -- Alexander Disease and Astrotherapeutics -- Role of Astrocytes in Central Nervous System Traum -- Astroglial and Neuronal Integrity During Cortical Spreading Depolarization -- Crucial role for astrocytes in epilepsy -- Microglial Biology in Neuroinflammatory Disease: Pharmaco-industrial Approach to Target Validation -- The Role of Astrocytes in Huntington's Disease -- Amyotrophic Lateral Sclerosis: A Glial Perspective -- Complex and Associated Astroglial and Microglial Changes during the Progression of Alzheimer´s Disease -- Possible Therapeutic Targets in Microglia -- Novel Therapeutic Approaches to Malignant Gliomas -- Hepatic encephalopathy: A Primary Neurogliopathy -- Astroglia and Severe Mental Illness: A Role for Glutamate Microdomains -- Emerging Roles for Glial Pathology in Addiction -- Astroglial Connexins as Elements of Sleep-wake Cycle Regulation and Dysfunction -- Experimental Treatment of Acquired and Inherited Neuropathies -- Satellite glial cells as target for chronic pain therapy -- Enteric Glial Cells: Implications in Gut Pathology.
Record Nr. UNINA-9910298349903321
New York, NY : , : Springer New York : , : Imprint : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Physiology and Pathophysiology of Oligodendroglia / / edited by Chenju Yi, Arthur Butt, Alexei Verkhratsky, Jianqin Niu
Physiology and Pathophysiology of Oligodendroglia / / edited by Chenju Yi, Arthur Butt, Alexei Verkhratsky, Jianqin Niu
Autore Yi Chenju
Edizione [1st ed. 2025.]
Pubbl/distr/stampa Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
Descrizione fisica 1 online resource (676 pages)
Disciplina 612.81046
Altri autori (Persone) ButtArthur
VerkhratskyAlexei
NiuJianqin
Collana Advances in Neurobiology
Soggetto topico Neurophysiology
Neurons
Neurosciences
Cellular Neuroscience
Neuroscience
ISBN 3-031-87919-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Chapter 1: Oligodendroglial lineage, myelin and white matter: defining the connectome of the human brain -- Part I: Physiology of oligodendroglia -- Chapter 2: Evolution of myelin and oligodendroglia -- Chapter 3: Development of oligodendroglia and myelin -- Chapter 4: Seeing is believing: insights into myelination and remyelination in zebrafish -- Chapter 5: Morphology of oligodendroglial cells and myelin -- Chapter 6: Physiology of oligodendroglial cells -- Chapter 7: Biochemistry and structure of myelin -- Chapter 8: Plasticity of myelination -- Part II: Pathophysiology of oligodendroglia -- Chapter 9: Demyelination and remyelination: General principles -- Chapter 10: Leukomalacia -- Chapter 11: White matter injury in the brain and spinal cord -- Chapter 12: Multiple sclerosis -- Chapter 13: Ageing and neurodegeneration of oligodendroglia -- Chapter 14: Protein pathologies in oligodendroglia in neurodegenerative diseases -- Chapter 15: Mental disorders -- Chapter 16: Neuromyelitis Optica -- Epilogue.
Record Nr. UNINA-9911010529503321
Yi Chenju  
Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
Materiale a stampa
Lo trovi qui: Univ. Federico II
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