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Genomics [[electronic resource] ] : applications in human biology / / Sandy B. Primrose, Richard Twyman
| Genomics [[electronic resource] ] : applications in human biology / / Sandy B. Primrose, Richard Twyman |
| Autore | Primrose S. B |
| Pubbl/distr/stampa | Malden, MA, : Blackwell Pub., c2004 |
| Descrizione fisica | 1 online resource (220 p.) |
| Disciplina |
611.018166
616/.042 |
| Altri autori (Persone) | TwymanRichard M |
| Soggetto topico |
Medical genetics
Genomics Pharmaceutical biotechnology Molecular biology |
| ISBN |
1-281-32227-X
9786611322274 0-470-75128-2 0-470-75127-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biotechnology and genomics in medicine -- An overview of genomics -- Genomics and the challenge of infectious disease -- Analysing and treating genetic diseases -- Diagnosis and treatment of cancer -- The large scale production of biopharmaceuticals -- Genomics and the development of new chemical entities -- Gene and cell therapies. |
| Record Nr. | UNINA-9910145436903321 |
Primrose S. B
|
||
| Malden, MA, : Blackwell Pub., c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genomics [[electronic resource] ] : applications in human biology / / Sandy B. Primrose, Richard Twyman
| Genomics [[electronic resource] ] : applications in human biology / / Sandy B. Primrose, Richard Twyman |
| Autore | Primrose S. B |
| Pubbl/distr/stampa | Malden, MA, : Blackwell Pub., c2004 |
| Descrizione fisica | 1 online resource (220 p.) |
| Disciplina |
611.018166
616/.042 |
| Altri autori (Persone) | TwymanRichard M |
| Soggetto topico |
Medical genetics
Genomics Pharmaceutical biotechnology Molecular biology |
| ISBN |
1-281-32227-X
9786611322274 0-470-75128-2 0-470-75127-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biotechnology and genomics in medicine -- An overview of genomics -- Genomics and the challenge of infectious disease -- Analysing and treating genetic diseases -- Diagnosis and treatment of cancer -- The large scale production of biopharmaceuticals -- Genomics and the development of new chemical entities -- Gene and cell therapies. |
| Record Nr. | UNISA-996218592303316 |
|
Primrose S. B
|
||
| Malden, MA, : Blackwell Pub., c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Genomics [[electronic resource] ] : applications in human biology / / Sandy B. Primrose, Richard Twyman
| Genomics [[electronic resource] ] : applications in human biology / / Sandy B. Primrose, Richard Twyman |
| Autore | Primrose S. B |
| Pubbl/distr/stampa | Malden, MA, : Blackwell Pub., c2004 |
| Descrizione fisica | 1 online resource (220 p.) |
| Disciplina |
611.018166
616/.042 |
| Altri autori (Persone) | TwymanRichard M |
| Soggetto topico |
Medical genetics
Genomics Pharmaceutical biotechnology Molecular biology |
| ISBN |
1-281-32227-X
9786611322274 0-470-75128-2 0-470-75127-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biotechnology and genomics in medicine -- An overview of genomics -- Genomics and the challenge of infectious disease -- Analysing and treating genetic diseases -- Diagnosis and treatment of cancer -- The large scale production of biopharmaceuticals -- Genomics and the development of new chemical entities -- Gene and cell therapies. |
| Record Nr. | UNINA-9910830803203321 |
|
Primrose S. B
|
||
| Malden, MA, : Blackwell Pub., c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genomics : applications in human biology / / Sandy B. Primrose, Richard Twyman
| Genomics : applications in human biology / / Sandy B. Primrose, Richard Twyman |
| Autore | Primrose S. B |
| Pubbl/distr/stampa | Malden, MA, : Blackwell Pub., c2004 |
| Descrizione fisica | 1 online resource (220 p.) |
| Disciplina | 616/.042 |
| Altri autori (Persone) | TwymanRichard M |
| Soggetto topico |
Medical genetics
Genomics Pharmaceutical biotechnology Molecular biology |
| ISBN |
1-281-32227-X
9786611322274 0-470-75128-2 0-470-75127-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biotechnology and genomics in medicine -- An overview of genomics -- Genomics and the challenge of infectious disease -- Analysing and treating genetic diseases -- Diagnosis and treatment of cancer -- The large scale production of biopharmaceuticals -- Genomics and the development of new chemical entities -- Gene and cell therapies. |
| Record Nr. | UNINA-9910877991303321 |
|
Primrose S. B
|
||
| Malden, MA, : Blackwell Pub., c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Principles of genome analysis and genomics [[electronic resource] /] / Sandy B. Primrose, Richard M. Twyman
| Principles of genome analysis and genomics [[electronic resource] /] / Sandy B. Primrose, Richard M. Twyman |
| Autore | Primrose S. B |
| Edizione | [3rd ed.] |
| Pubbl/distr/stampa | Malden, Mass., : Blackwell Pub., 2003 |
| Descrizione fisica | 1 online resource (272 p.) |
| Disciplina | 572.8/633 |
| Altri autori (Persone) | TwymanRichard M |
| Soggetto topico |
Gene mapping
Nucleotide sequence Genomics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-11753-X
9786612117534 1-4443-1128-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Abbreviations; CHAPTER 1 Setting the scene: the new science of genomics; Introduction; Physical mapping of genomes; Sequencing whole genomes; Benefits of genome sequencing; Outline of the rest of the book; Terminology; Keeping up to date; Suggested reading; Useful websites; CHAPTER 2 The organization and structure of genomes; Introduction; Genome size; Sequence complexity; Introns and exons; Genome structure in viruses and prokaryotes; The organization of organelle genomes; The organization of nuclear DNA in eukaryotes; Suggested reading; Useful websites
CHAPTER 3 Subdividing the genome Introduction; Fragmentation of DNA with restriction enzymes; Separating large fragments of DNA; Isolation of chromosomes; Chromosome microdissection; Vectors for cloning DNA; Yeast artificial chromosomes; P1-derived and bacterial artificial chromosomes as alternatives to yeast artificial chromosomes; Retrofitting; Choice of vector; Suggested reading; Useful website; CHAPTER 4 Assembling a physical map of the genome; Introduction; Restriction enzyme fingerprinting; Marker sequences; Hybridization assays; Physical mapping without cloning Integration of different mapping methods Suggested reading; Useful websites; CHAPTER 5 Sequencing methods and strategies; Basic DNA sequencing; Modifications of chain-terminator sequencing; Automated DNA sequencing; DNA sequencing by capillary array electrophoresis; Base calling and sequence accuracy; High throughput sequencing; Sequencing strategies; Alternative DNA sequencing methodologies; Suggested reading; Useful websites; CHAPTER 6 Genome annotation and bioinformatics; Introduction; Traditional routes to gene identification; Databases; Overview of sequence analysis Detecting open-reading frames Software programs for finding genes; Using homology to find genes; Analysis of non-coding RNA and extragenic DNA; Identifying the function of a new gene; Secondary databases of functional domains; Gene ontology; Analyses not based on homology; Genome annotation; Molecular phylogenetics; Suggested reading; Useful websites; CHAPTER 7 Comparative genomics; Introduction; Orthologues,paralogues and gene displacement; Protein evolution by exon shuffing; Comparative genomics of prokaryotes; Comparative genomics of organelles; Comparative genomics of eukaryotes Other aspects of comparative genomics Suggested reading; Useful websites; CHAPTER 8 Protein structural genomics; Introduction; Determining gene function by sequence comparison; Determining gene function through conserved protein structure; Approaches to protein structural genomics; Suggested reading; Useful website; CHAPTER 9 Global expression pro ling; Introduction; Traditional approaches to expression pro ling; Global analysis of RNA expression; Global analysis of protein expression; Suggested reading; Useful websites; CHAPTER 10 Comprehensive mutant libraries; Introduction High-throughput systematic gene knockout |
| Record Nr. | UNINA-9910454647803321 |
|
Primrose S. B
|
||
| Malden, Mass., : Blackwell Pub., 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Principles of genome analysis and genomics [[electronic resource] /] / Sandy B. Primrose, Richard M. Twyman
| Principles of genome analysis and genomics [[electronic resource] /] / Sandy B. Primrose, Richard M. Twyman |
| Autore | Primrose S. B |
| Edizione | [3rd ed.] |
| Pubbl/distr/stampa | Malden, Mass., : Blackwell Pub., 2003 |
| Descrizione fisica | 1 online resource (272 p.) |
| Disciplina | 572.8/633 |
| Altri autori (Persone) | TwymanRichard M |
| Soggetto topico |
Gene mapping
Nucleotide sequence Genomics |
| ISBN |
1-282-11753-X
9786612117534 1-4443-1128-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Abbreviations; CHAPTER 1 Setting the scene: the new science of genomics; Introduction; Physical mapping of genomes; Sequencing whole genomes; Benefits of genome sequencing; Outline of the rest of the book; Terminology; Keeping up to date; Suggested reading; Useful websites; CHAPTER 2 The organization and structure of genomes; Introduction; Genome size; Sequence complexity; Introns and exons; Genome structure in viruses and prokaryotes; The organization of organelle genomes; The organization of nuclear DNA in eukaryotes; Suggested reading; Useful websites
CHAPTER 3 Subdividing the genome Introduction; Fragmentation of DNA with restriction enzymes; Separating large fragments of DNA; Isolation of chromosomes; Chromosome microdissection; Vectors for cloning DNA; Yeast artificial chromosomes; P1-derived and bacterial artificial chromosomes as alternatives to yeast artificial chromosomes; Retrofitting; Choice of vector; Suggested reading; Useful website; CHAPTER 4 Assembling a physical map of the genome; Introduction; Restriction enzyme fingerprinting; Marker sequences; Hybridization assays; Physical mapping without cloning Integration of different mapping methods Suggested reading; Useful websites; CHAPTER 5 Sequencing methods and strategies; Basic DNA sequencing; Modifications of chain-terminator sequencing; Automated DNA sequencing; DNA sequencing by capillary array electrophoresis; Base calling and sequence accuracy; High throughput sequencing; Sequencing strategies; Alternative DNA sequencing methodologies; Suggested reading; Useful websites; CHAPTER 6 Genome annotation and bioinformatics; Introduction; Traditional routes to gene identification; Databases; Overview of sequence analysis Detecting open-reading frames Software programs for finding genes; Using homology to find genes; Analysis of non-coding RNA and extragenic DNA; Identifying the function of a new gene; Secondary databases of functional domains; Gene ontology; Analyses not based on homology; Genome annotation; Molecular phylogenetics; Suggested reading; Useful websites; CHAPTER 7 Comparative genomics; Introduction; Orthologues,paralogues and gene displacement; Protein evolution by exon shuffing; Comparative genomics of prokaryotes; Comparative genomics of organelles; Comparative genomics of eukaryotes Other aspects of comparative genomics Suggested reading; Useful websites; CHAPTER 8 Protein structural genomics; Introduction; Determining gene function by sequence comparison; Determining gene function through conserved protein structure; Approaches to protein structural genomics; Suggested reading; Useful website; CHAPTER 9 Global expression pro ling; Introduction; Traditional approaches to expression pro ling; Global analysis of RNA expression; Global analysis of protein expression; Suggested reading; Useful websites; CHAPTER 10 Comprehensive mutant libraries; Introduction High-throughput systematic gene knockout |
| Record Nr. | UNINA-9910782618103321 |
|
Primrose S. B
|
||
| Malden, Mass., : Blackwell Pub., 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Principles of genome analysis and genomics / / Sandy B. Primrose, Richard M. Twyman
| Principles of genome analysis and genomics / / Sandy B. Primrose, Richard M. Twyman |
| Autore | Primrose S. B |
| Edizione | [3rd ed.] |
| Pubbl/distr/stampa | Malden, Mass., : Blackwell Pub., 2003 |
| Descrizione fisica | 1 online resource (272 p.) |
| Disciplina | 572.8/633 |
| Altri autori (Persone) | TwymanRichard M |
| Soggetto topico |
Gene mapping
Nucleotide sequence Genomics |
| ISBN |
1-282-11753-X
9786612117534 1-4443-1128-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Abbreviations; CHAPTER 1 Setting the scene: the new science of genomics; Introduction; Physical mapping of genomes; Sequencing whole genomes; Benefits of genome sequencing; Outline of the rest of the book; Terminology; Keeping up to date; Suggested reading; Useful websites; CHAPTER 2 The organization and structure of genomes; Introduction; Genome size; Sequence complexity; Introns and exons; Genome structure in viruses and prokaryotes; The organization of organelle genomes; The organization of nuclear DNA in eukaryotes; Suggested reading; Useful websites
CHAPTER 3 Subdividing the genome Introduction; Fragmentation of DNA with restriction enzymes; Separating large fragments of DNA; Isolation of chromosomes; Chromosome microdissection; Vectors for cloning DNA; Yeast artificial chromosomes; P1-derived and bacterial artificial chromosomes as alternatives to yeast artificial chromosomes; Retrofitting; Choice of vector; Suggested reading; Useful website; CHAPTER 4 Assembling a physical map of the genome; Introduction; Restriction enzyme fingerprinting; Marker sequences; Hybridization assays; Physical mapping without cloning Integration of different mapping methods Suggested reading; Useful websites; CHAPTER 5 Sequencing methods and strategies; Basic DNA sequencing; Modifications of chain-terminator sequencing; Automated DNA sequencing; DNA sequencing by capillary array electrophoresis; Base calling and sequence accuracy; High throughput sequencing; Sequencing strategies; Alternative DNA sequencing methodologies; Suggested reading; Useful websites; CHAPTER 6 Genome annotation and bioinformatics; Introduction; Traditional routes to gene identification; Databases; Overview of sequence analysis Detecting open-reading frames Software programs for finding genes; Using homology to find genes; Analysis of non-coding RNA and extragenic DNA; Identifying the function of a new gene; Secondary databases of functional domains; Gene ontology; Analyses not based on homology; Genome annotation; Molecular phylogenetics; Suggested reading; Useful websites; CHAPTER 7 Comparative genomics; Introduction; Orthologues,paralogues and gene displacement; Protein evolution by exon shuffing; Comparative genomics of prokaryotes; Comparative genomics of organelles; Comparative genomics of eukaryotes Other aspects of comparative genomics Suggested reading; Useful websites; CHAPTER 8 Protein structural genomics; Introduction; Determining gene function by sequence comparison; Determining gene function through conserved protein structure; Approaches to protein structural genomics; Suggested reading; Useful website; CHAPTER 9 Global expression pro ling; Introduction; Traditional approaches to expression pro ling; Global analysis of RNA expression; Global analysis of protein expression; Suggested reading; Useful websites; CHAPTER 10 Comprehensive mutant libraries; Introduction High-throughput systematic gene knockout |
| Record Nr. | UNINA-9910811555503321 |
|
Primrose S. B
|
||
| Malden, Mass., : Blackwell Pub., 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||