Systems biology in psychiatric research [[electronic resource] ] : from high-throughput data to mathematical modeling / / edited by Felix Tretter ... [et al.] |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2010 |
Descrizione fisica | 1 online resource (380 p.) |
Disciplina |
616.89
616.890072 |
Altri autori (Persone) | TretterFelix |
Soggetto topico | Psychiatry - Research |
Soggetto genere / forma | Electronic books. |
ISBN |
1-282-69064-7
9786612690648 3-527-63027-9 3-527-63028-7 |
Classificazione | 44.91 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Systems Biology in Psychiatric Research: From High-Throughput Data to Mathematical Modeling; Foreword; Contents; Preface; List of Contributors; Part One: Introduction; 1 Philosophical Aspects of Neuropsychiatry; 1.1 Development of Research Paradigms and Strategies in Psychiatry; 1.2 The Mind-Body Problem - Philosophy of Mind; 1.2.1 Monism and Dualism; 1.2.2 Correlation; 1.2.3 Identity Theory and its Problems; 1.2.4 Causation; 1.2.5 Supervenience; 1.3 The Conditions of Scientific Knowledge - Philosophy of Science; 1.4 Experimental Research - From Observation to Theory
1.4.1 Hypotheses and Theory1.4.2 The ""Epistemic Cycle""; 1.4.3 Top-Down Analysis - Reductionism?; 1.4.4 Bottom-Up Explanations - Holism?; 1.5 Theoretical (Neuro)psychiatry; 1.6 Systems Thinking; 1.7 Perspectives - Towards a ""Neurophilosophy""; References; 2 Neuropsychiatry - Subject, Concepts, Methods, and Computational Models; 2.1 Introduction; 2.2 Psychiatric Fundamentals of Neuropsychiatry; 2.2.1 General Psychiatry; 2.2.2 Psychopathology; 2.2.2.1 Quantitative Psychopathology; 2.2.2.2 Theoretical Psychopathology; 2.2.3 Psychiatric Diagnoses; 2.2.3.1 Diagnostic Criteria 2.2.4 Theoretical Psychiatry2.2.4.1 ""Computational Neuropsychiatry""; 2.2.4.2 ""Systems Neuropsychiatry""; 2.3 Neurobiological Fundamentals of Neuropsychiatry; 2.3.1 Basic Findings of (Neuro)biological Psychiatry; 2.3.1.1 Neuropsychopathology; 2.3.1.2 Neurobiological Methods; 2.3.1.3 Experimental Paradigms; 2.3.1.4 Structure and Function of the Brain; 2.3.1.5 Global Circuits and their Connectivities; 2.3.1.6 Local Networks of Neurons; 2.3.1.7 Prefrontal Network in Schizophrenia; 2.3.2 Neuron; 2.3.2.1 Electrical Signaling of the Neuron; 2.3.3 Synapse; 2.3.3.1 Receptors 2.3.4 The Cell as a System of Interacting Molecules2.3.4.1 Intracellular Signal Cascades - From Receptor to Genome; 2.3.4.2 Modeling Signal Transduction Networks Relevant in Schizophrenia; 2.3.4.3 Genomics and Proteomics; 2.3.4.4 Gene Regulation - Circular Signaling Pathways; 2.3.4.5 Systems Biology of the Neuron; 2.3.5 The Brain as a Neurochemical Oscillator; 2.3.5.1 Neurochemical Interaction Matrix; 2.3.5.2 ""Neurochemical Mobile""; 2.4 Conclusions and Perspectives; References; 3 Introduction to Systems Biology; 3.1 Introduction; 3.1.1 What is Systems Biology?; 3.1.2 Purpose of Modeling 3.1.3 Levels of Modeling3.2 Data Analysis; 3.2.1 Types of Data; 3.2.1.1 Purification; 3.2.1.2 Detection; 3.2.1.3 Large-Scale Analyses; 3.2.1.4 Identification of Components; 3.2.2 Working with Data; 3.2.2.1 Different Clustering Approaches; 3.2.2.2 Principal Component Analysis; 3.3 ODE Modeling; 3.3.1 Differential Equations; 3.3.2 Stoichiometric Matrix; 3.3.3 Reaction Kinetics; 3.3.4 Steady States; 3.3.5 Metabolic Control Analysis; 3.3.6 Simulating Models; 3.3.7 Parameter Estimation; 3.4 Results Gained from Systems Biology; 3.4.1 Just-in-Time Transcription 3.5 Standard Formats, Databases, and Tools |
Record Nr. | UNINA-9910140556003321 |
Weinheim, : Wiley-VCH, 2010 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Systems biology in psychiatric research [[electronic resource] ] : from high-throughput data to mathematical modeling / / edited by Felix Tretter ... [et al.] |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2010 |
Descrizione fisica | 1 online resource (380 p.) |
Disciplina |
616.89
616.890072 |
Altri autori (Persone) | TretterFelix |
Soggetto topico | Psychiatry - Research |
ISBN |
1-282-69064-7
9786612690648 3-527-63027-9 3-527-63028-7 |
Classificazione | 44.91 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Systems Biology in Psychiatric Research: From High-Throughput Data to Mathematical Modeling; Foreword; Contents; Preface; List of Contributors; Part One: Introduction; 1 Philosophical Aspects of Neuropsychiatry; 1.1 Development of Research Paradigms and Strategies in Psychiatry; 1.2 The Mind-Body Problem - Philosophy of Mind; 1.2.1 Monism and Dualism; 1.2.2 Correlation; 1.2.3 Identity Theory and its Problems; 1.2.4 Causation; 1.2.5 Supervenience; 1.3 The Conditions of Scientific Knowledge - Philosophy of Science; 1.4 Experimental Research - From Observation to Theory
1.4.1 Hypotheses and Theory1.4.2 The ""Epistemic Cycle""; 1.4.3 Top-Down Analysis - Reductionism?; 1.4.4 Bottom-Up Explanations - Holism?; 1.5 Theoretical (Neuro)psychiatry; 1.6 Systems Thinking; 1.7 Perspectives - Towards a ""Neurophilosophy""; References; 2 Neuropsychiatry - Subject, Concepts, Methods, and Computational Models; 2.1 Introduction; 2.2 Psychiatric Fundamentals of Neuropsychiatry; 2.2.1 General Psychiatry; 2.2.2 Psychopathology; 2.2.2.1 Quantitative Psychopathology; 2.2.2.2 Theoretical Psychopathology; 2.2.3 Psychiatric Diagnoses; 2.2.3.1 Diagnostic Criteria 2.2.4 Theoretical Psychiatry2.2.4.1 ""Computational Neuropsychiatry""; 2.2.4.2 ""Systems Neuropsychiatry""; 2.3 Neurobiological Fundamentals of Neuropsychiatry; 2.3.1 Basic Findings of (Neuro)biological Psychiatry; 2.3.1.1 Neuropsychopathology; 2.3.1.2 Neurobiological Methods; 2.3.1.3 Experimental Paradigms; 2.3.1.4 Structure and Function of the Brain; 2.3.1.5 Global Circuits and their Connectivities; 2.3.1.6 Local Networks of Neurons; 2.3.1.7 Prefrontal Network in Schizophrenia; 2.3.2 Neuron; 2.3.2.1 Electrical Signaling of the Neuron; 2.3.3 Synapse; 2.3.3.1 Receptors 2.3.4 The Cell as a System of Interacting Molecules2.3.4.1 Intracellular Signal Cascades - From Receptor to Genome; 2.3.4.2 Modeling Signal Transduction Networks Relevant in Schizophrenia; 2.3.4.3 Genomics and Proteomics; 2.3.4.4 Gene Regulation - Circular Signaling Pathways; 2.3.4.5 Systems Biology of the Neuron; 2.3.5 The Brain as a Neurochemical Oscillator; 2.3.5.1 Neurochemical Interaction Matrix; 2.3.5.2 ""Neurochemical Mobile""; 2.4 Conclusions and Perspectives; References; 3 Introduction to Systems Biology; 3.1 Introduction; 3.1.1 What is Systems Biology?; 3.1.2 Purpose of Modeling 3.1.3 Levels of Modeling3.2 Data Analysis; 3.2.1 Types of Data; 3.2.1.1 Purification; 3.2.1.2 Detection; 3.2.1.3 Large-Scale Analyses; 3.2.1.4 Identification of Components; 3.2.2 Working with Data; 3.2.2.1 Different Clustering Approaches; 3.2.2.2 Principal Component Analysis; 3.3 ODE Modeling; 3.3.1 Differential Equations; 3.3.2 Stoichiometric Matrix; 3.3.3 Reaction Kinetics; 3.3.4 Steady States; 3.3.5 Metabolic Control Analysis; 3.3.6 Simulating Models; 3.3.7 Parameter Estimation; 3.4 Results Gained from Systems Biology; 3.4.1 Just-in-Time Transcription 3.5 Standard Formats, Databases, and Tools |
Record Nr. | UNINA-9910830291503321 |
Weinheim, : Wiley-VCH, 2010 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Systems biology in psychiatric research : from high-throughput data to mathematical modeling / / edited by Felix Tretter ... [et al.] |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2010 |
Descrizione fisica | 1 online resource (380 p.) |
Disciplina |
616.89
616.890072 |
Altri autori (Persone) | TretterFelix |
Soggetto topico | Psychiatry - Research |
ISBN |
1-282-69064-7
9786612690648 3-527-63027-9 3-527-63028-7 |
Classificazione | 44.91 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Systems Biology in Psychiatric Research: From High-Throughput Data to Mathematical Modeling; Foreword; Contents; Preface; List of Contributors; Part One: Introduction; 1 Philosophical Aspects of Neuropsychiatry; 1.1 Development of Research Paradigms and Strategies in Psychiatry; 1.2 The Mind-Body Problem - Philosophy of Mind; 1.2.1 Monism and Dualism; 1.2.2 Correlation; 1.2.3 Identity Theory and its Problems; 1.2.4 Causation; 1.2.5 Supervenience; 1.3 The Conditions of Scientific Knowledge - Philosophy of Science; 1.4 Experimental Research - From Observation to Theory
1.4.1 Hypotheses and Theory1.4.2 The ""Epistemic Cycle""; 1.4.3 Top-Down Analysis - Reductionism?; 1.4.4 Bottom-Up Explanations - Holism?; 1.5 Theoretical (Neuro)psychiatry; 1.6 Systems Thinking; 1.7 Perspectives - Towards a ""Neurophilosophy""; References; 2 Neuropsychiatry - Subject, Concepts, Methods, and Computational Models; 2.1 Introduction; 2.2 Psychiatric Fundamentals of Neuropsychiatry; 2.2.1 General Psychiatry; 2.2.2 Psychopathology; 2.2.2.1 Quantitative Psychopathology; 2.2.2.2 Theoretical Psychopathology; 2.2.3 Psychiatric Diagnoses; 2.2.3.1 Diagnostic Criteria 2.2.4 Theoretical Psychiatry2.2.4.1 ""Computational Neuropsychiatry""; 2.2.4.2 ""Systems Neuropsychiatry""; 2.3 Neurobiological Fundamentals of Neuropsychiatry; 2.3.1 Basic Findings of (Neuro)biological Psychiatry; 2.3.1.1 Neuropsychopathology; 2.3.1.2 Neurobiological Methods; 2.3.1.3 Experimental Paradigms; 2.3.1.4 Structure and Function of the Brain; 2.3.1.5 Global Circuits and their Connectivities; 2.3.1.6 Local Networks of Neurons; 2.3.1.7 Prefrontal Network in Schizophrenia; 2.3.2 Neuron; 2.3.2.1 Electrical Signaling of the Neuron; 2.3.3 Synapse; 2.3.3.1 Receptors 2.3.4 The Cell as a System of Interacting Molecules2.3.4.1 Intracellular Signal Cascades - From Receptor to Genome; 2.3.4.2 Modeling Signal Transduction Networks Relevant in Schizophrenia; 2.3.4.3 Genomics and Proteomics; 2.3.4.4 Gene Regulation - Circular Signaling Pathways; 2.3.4.5 Systems Biology of the Neuron; 2.3.5 The Brain as a Neurochemical Oscillator; 2.3.5.1 Neurochemical Interaction Matrix; 2.3.5.2 ""Neurochemical Mobile""; 2.4 Conclusions and Perspectives; References; 3 Introduction to Systems Biology; 3.1 Introduction; 3.1.1 What is Systems Biology?; 3.1.2 Purpose of Modeling 3.1.3 Levels of Modeling3.2 Data Analysis; 3.2.1 Types of Data; 3.2.1.1 Purification; 3.2.1.2 Detection; 3.2.1.3 Large-Scale Analyses; 3.2.1.4 Identification of Components; 3.2.2 Working with Data; 3.2.2.1 Different Clustering Approaches; 3.2.2.2 Principal Component Analysis; 3.3 ODE Modeling; 3.3.1 Differential Equations; 3.3.2 Stoichiometric Matrix; 3.3.3 Reaction Kinetics; 3.3.4 Steady States; 3.3.5 Metabolic Control Analysis; 3.3.6 Simulating Models; 3.3.7 Parameter Estimation; 3.4 Results Gained from Systems Biology; 3.4.1 Just-in-Time Transcription 3.5 Standard Formats, Databases, and Tools |
Record Nr. | UNINA-9910876753003321 |
Weinheim, : Wiley-VCH, 2010 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|