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A Practice of Anesthesia for Infants and Children
| A Practice of Anesthesia for Infants and Children |
| Autore | Cote Charles J |
| Edizione | [6th ed.] |
| Pubbl/distr/stampa | Philadelphia : , : Elsevier, , 2019 |
| Descrizione fisica | 1 online resource (1280 pages) : illustrations (chiefly color) |
| Disciplina | 617.9/6083 |
| Altri autori (Persone) |
LermanJerrold
TodresI. David |
| Soggetto topico |
Pediatric anesthesia
Anesthesia Child Humans Infant |
| ISBN | 0-323-55162-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover -- Endsheet 2 -- A Practice of Anesthesia for Infants and Children -- Copyright Page -- Dedication -- Contributors -- Preface -- Acknowledgments -- Table Of Contents -- Video Contents -- I Introduction -- 1 The Practice of Pediatric Anesthesia -- Preoperative Evaluation and Management -- Parents and Child -- The Anesthesiologist -- Informed Consent -- Operating Room and Monitoring -- Induction and Maintenance of Anesthesia -- Clinical Monitors -- Sight -- Hearing -- Touch -- Airway and Ventilation -- Fluids and Perfusion -- Conduct of the Anesthesia Team -- The Postanesthesia Care Unit -- Postoperative Visit -- Summary -- 2 Growth and Development -- Normal and Abnormal Growth and Maturation -- Gestational Age Assessment -- Weight and Length -- Head Circumference -- Face -- Teeth -- Airway and Respiratory System -- Upper Airway Development -- Respiratory System Development -- Transition to Air Breathing -- Mechanics of Breathing -- Chest Wall and Respiratory Muscles -- Elastic Properties of the Lung -- Static Lung Volumes -- Total Lung Capacity -- Functional Residual Capacity -- Closing Capacity -- Airway Dynamics -- Resistance and Conductance -- Distribution of Resistance -- Inspiratory and Expiratory Flow Limitation -- Regulation of Breathing -- Cardiovascular System -- Heart Rate -- Blood Pressure -- Cardiac Output -- Normal Electrocardiographic Findings -- Renal System -- Digestive and Endocrine System -- Hepatic System -- Physiologic Jaundice -- Gastrointestinal Tract -- Pancreas -- Hematopoietic and Immunologic System -- Hemoglobin -- Leukocyte and Immunology -- Platelets -- Coagulation -- Polycythemia -- Neurologic Development and Cognitive Development Issues -- Neurologic Development -- Interactions With the External World During Growth and Development -- Acknowledgment -- Annotated References -- References.
3 Perioperative Behavioral Stress in Children -- Developmental Issues -- Cognitive Development and Understanding of Illness -- Attachment -- Temperament -- Preoperative Anxiety -- Risk Factors -- Behavioral Interventions -- Preoperative Preparation Programs -- Parental Presence During Induction of Anesthesia -- The Preoperative Interview -- Health Care Provider Interventions -- Pharmacologic Interventions -- Pharmacologic Interventions Versus Behavioral Interventions -- Postoperative Outcomes -- Emergence Delirium -- Sleep Changes -- Other Behavioral Changes -- Intraoperative Clinical Outcomes -- Summary -- Annotated References -- References -- 4 Preoperative Evaluation, Premedication, and Induction of Anesthesia -- Preparation of Children for Anesthesia -- Fasting -- Piercings -- Primary and Secondary Smoking -- Primary Smoking -- Secondary Smoking -- Psychological Preparation of Children for Surgery -- Child Development and Behavior -- Parental Presence During Induction -- History of Present Illness -- Past/Other Medical History -- Herbal Remedies -- Anesthesia and Vaccination -- Allergies to Medications and Latex -- Family History -- Laboratory Data -- Pregnancy Testing -- Premedication and Induction Principles -- General Principles -- Medications -- Tranquilizers -- Benzodiazepines -- Barbiturates -- Nonbarbiturate Sedatives -- Opioids -- Ketamine -- α2-Agonists -- Antihistamines -- Anticholinergic Drugs -- Topical Anesthetics -- Nonopioid Analgesics -- Antiemetics -- Corticosteroids -- Insulin -- Antibiotics -- Antacids, H2-Receptor Antagonists, and Gastrointestinal Motility Drugs -- Induction of Anesthesia -- Preparation for Induction -- Inhalation Induction -- Inhalation With Sevoflurane -- Inhalation Induction With Halothane -- Inhalation Induction With Desflurane -- Hypnotic Induction -- Modified Single-Breath Induction. Intravenous Induction -- Thiopental -- Methohexital -- Propofol -- Etomidate -- Ketamine -- Intramuscular Induction -- Rectal Induction -- Full Stomach and Rapid-Sequence Induction -- Special Problems -- The Fearful Child -- Autism -- Anemia -- Upper Respiratory Tract Infection -- Obesity -- Obstructive Sleep Apnea Syndrome -- Asymptomatic Cardiac Murmurs -- Fever -- Postanesthesia Apnea in Former Preterm Infants -- Hyperalimentation -- Diabetes -- Bronchopulmonary Dysplasia -- Seizure Disorder -- Sickle Cell Disease -- Acknowledgment -- Annotated References -- References -- 5 Ethical Issues in Pediatric Anesthesiology -- Informed Consent -- The Informed Consent Process -- Assent: The Role of the Patient -- Informed Permission, the Best Interest Standard and the Harm Threshold Standard -- Disclosure -- Informed Refusal -- "Doctor, If This Were Your Child, What Would You Do?" -- Disclosure and Apology of Medical Errors -- Special Situations in Pediatric Informed Consent -- Confidentially for Adolescents -- The Pregnant Adolescent -- The Adolescent and Abortion -- Children of Jehovah's Witnesses -- Emergency Care -- The Impaired Parent -- End-of-Life Issues -- Forgoing Potentially Life-Sustaining Treatment -- Perioperative Limitations on Life-Sustaining Treatment -- Barriers to Honoring Preferences for Resuscitation -- Physicians Orders for Life-Sustaining Treatment -- Potentially Inappropriate Interventions -- Improving Communication in Pediatric Intensive Care Units -- Organ Donation After Cardiac Death -- Clinical and Academic Practice Issues -- Pediatric Research -- Minimal Risk -- Minor Increase Over Minimal Risk -- Socioeconomic Concerns and Distribution of Risk -- Imperative for Pharmacologic Research -- Managing Potential Conflicts of Interest -- Conducting Research -- Interaction With Industry -- Production Pressure. Physician Obligations, Advocacy, and Good Citizenship -- Participating in Patient Safety Efforts -- Treating Suffering -- Suspicion of Child Maltreatment -- The Ethics Consultation Service -- Annotated References -- References -- II Drug and Fluid Therapy -- 6 Pharmacogenomics -- Historical Perspectives -- Basic Concepts and Nomenclature -- Hepatic Metabolism and Developmental Pharmacogenetics -- Cytochromes P-450: Phase I Reactions -- Developmental Changes of Specific Cytochromes -- Phase II Reactions -- Alterations in Biotransformation at Birth -- Genomics of Drug Metabolism, Exposure, and Effects -- Pharmacogenomics of Pain and Analgesia -- Pain Perception and Genetics -- Genetic Variations Affecting Opioid Pharmacokinetics -- Codeine -- Tramadol -- Hydrocodone -- Oxycodone -- Morphine -- Methadone -- Genetic Variations Affecting Opioid Pharmacodynamics -- Opioid Receptor (OPRM1) -- Blood-Brain Barrier Transporter (ABCB1) -- Opioid-Cannabinoid System Interactions -- Genes of Addiction -- Nonsteroidal Antiinflammatory Drugs and Genetics -- Acetaminophen and Genetics -- Chronic Pain, Persistent Postoperative Pain, and Genetics -- Pharmacogenomics Affecting Anesthesia -- Intravenous Anesthetics -- Propofol -- Inhalational Anesthetics -- Nitrous Oxide -- Benzodiazepines -- Neuromuscular Blocking Drugs -- Local Anesthetics -- Perioperative Outcomes -- Postoperative Nausea and Vomiting -- Perioperative Bleeding -- Hemodynamic Response -- Effect on Other Perioperative Outcomes -- Ancestry/Race and Genetics -- Pharmacogenomics Methods -- Common Genotyping Methods -- Common Limitations of Genetic Research Studies and Interpretation of Genetic Studies -- Current Costs of Genotyping and Third-Party Coverage for Genotyping -- Genetic Counseling -- Clinical Translation: Bench to Bedside: Where Are We Now? -- Conclusion -- Annotated References -- References. 7 Pharmacokinetics and Pharmacology of Drugs Used in Children -- Pharmacokinetic Principles and Calculations -- First-Order Kinetics -- Half-Life -- First-Order Single-Compartment Kinetics -- First-Order Multiple-Compartment Kinetics -- Zero-Order Kinetics -- Apparent Volume of Distribution -- Pharmacokinetic Example -- Repetitive Dosing and Drug Accumulation -- Steady State -- Loading Dose -- Population Modeling -- Pediatric Pharmacokinetic Considerations -- Size -- Maturation -- Organ Function -- Pharmacodynamic Models -- Minimal Effective Concentration -- Sigmoid Emax Model -- Quantal Effect Model -- Logistic Regression Model -- Linking Pharmacokinetics With Pharmacodynamics -- Drug Distribution -- Protein Binding -- Body Composition -- Regional Blood Flows -- Blood-Brain Barrier -- Absorption -- Enteral -- Cutaneous -- Intramuscular -- Nasal -- Bioavailability -- Metabolism and Excretion -- Hepatic Metabolism -- Phase I Reactions: Cytochrome P-450 -- Phase II Reactions -- Alterations in Biotransformation -- Extrahepatic Routes of Metabolic Clearance -- Renal Excretion -- Central Nervous System Effects -- Pharmacodynamics in Children -- Measurement of Pharmacodynamic Endpoints -- The Target Concentration Approach -- Defining Target Concentration -- Drug Interactions -- The Drug Approval Process, the Package Insert, and Drug Labeling -- Inhalation Anesthetic Agents -- Physicochemical Properties -- Pharmacokinetics of Inhaled Anesthetics -- Factors Affecting Delivery of Inhaled Anesthetics to the Lungs -- Inspired Concentration -- Alveolar Ventilation and Functional Residual Capacity -- Factors Affecting the Uptake (Removal) of Inhaled Anesthetics From the Lungs -- Cardiac Output -- Solubility -- Alveolar to Venous Partial Pressure Gradient -- Second Gas Effect -- Induction -- Control of Anesthetic Depth -- Shunts -- Wash-Out and Emergence. Pharmacodynamics of Inhaled Anesthetics. |
| Record Nr. | UNINA-9910583078703321 |
Cote Charles J
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| Philadelphia : , : Elsevier, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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A Practice of Anesthesia for Infants and Children
| A Practice of Anesthesia for Infants and Children |
| Edizione | [4th ed.] |
| Pubbl/distr/stampa | Philadelphia, PA, : Saunders/Elsevier, c2009 |
| Descrizione fisica | xxiii, 1167 p. : ill. (chiefly col.) |
| Disciplina | 617.9/6083 |
| Altri autori (Persone) |
CotéCharles J
LermanJerrold TodresI. David |
| Soggetto topico | Pediatric anesthesia |
| ISBN | 1-4377-1081-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996200106103316 |
| Philadelphia, PA, : Saunders/Elsevier, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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