Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Transcription factors in the nervous system [[electronic resource] ] : development, brain function and diseases / / edited by Gerald Thiel
| Transcription factors in the nervous system [[electronic resource] ] : development, brain function and diseases / / edited by Gerald Thiel |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (507 p.) |
| Disciplina | 616.8042 |
| Altri autori (Persone) | ThielGerald |
| Soggetto topico |
Transcription factors
Neural stem cells |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-85433-2
9786610854332 3-527-60803-6 3-527-60736-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Transcription Factors in the Nervous System; Contents; Preface; List of Contributors; Color Plates; Part I Transcription Factors in Neural Development; 1 Roles of Hes bHLH Factors in Neural Development; 1.1 Introduction; 1.2 Structure and Transcriptional Activities of Hes Factors; 1.3 Regulation of Hes Gene Expression; 1.4 Expression of Hes Genes in the Developing Nervous System; 1.5 Maintenance of Neural Stem Cells by Hes Genes; 1.6 Promotion of Gliogenesis by Hes Genes; 1.7 Maintenance of the Isthmic Organizer by Hes Genes; 1.8 Perspective; Acknowledgments; Abbreviations
2 The Role of Pax6 in the Nervous System during Development and in Adulthood: Master Control Regulator or Modular Function?Abstract; 2.1 Introduction; 2.2 Molecular Features of Pax6; 2.2.1 The Paired Domain; 2.2.2 The Paired-Type Homeodomain; 2.2.3 Different Pax6 Isoforms; 2.2.4 Protein-Protein Interactions; 2.2.5 Post-Translational Modifications of Pax6; 2.3 Function of Pax6 in Development; 2.3.1 Function of Pax6 in the Developing Eye; 2.3.2 Function of Pax6 in the Developing Brain; 2.3.2.1 Telencephalon; 2.3.2.2 Diencephalon; 2.3.2.3 Cerebellum; 2.3.2.4 Spinal Cord 2.4 Function of Pax6 in the Adult Brain2.5 Mechanisms of Pax6 Function; 2.6 Conclusions and Outlook; Abbreviations; 3 Phox2a and Phox2b: Essential Transcription Factors for Neuron Specification and Differentiation; Abstract; 3.1 Introduction; 3.2 Molecular Characteristics of Phox2 Genes and Proteins; 3.2.1 Sequence and Gene Structure Conservation in the Animal Kingdom; 3.2.2 Transcriptional Activation by Phox2 Proteins; 3.3 Physiological Relevance of Phox2 Transcription Factors; 3.3.1 Expression Pattern; 3.3.2 Effects of Phox2 Gene Mutations 3.3.2.1 Autonomic Neural Crest Derivatives and Visceral Sensory Ganglia3.3.2.2 Central Noradrenergic Neurons; 3.3.2.3 Autonomic Centers in the Hindbrain; 3.3.3 Human Mutations; 3.4 Molecular Mechanism of Action in Different Lineages; 3.4.1 Sympathetic Neurons; 3.4.2 Parasympathetic Neurons; 3.4.3 Enteric Neurons; 3.4.4 Visceral Sensory Neurons of the Geniculate, Petrosal and Nodose Ganglia; 3.4.5 Central Noradrenergic Neurons; 3.4.6 Autonomic Centers in the Hindbrain; 3.4.6.1 Afferent Visceral Centers; 3.4.6.2 Efferent Visceral Centers; 3.4.7 Oculomotor (nIII) and Trochlear (nIV) Centers 3.5 Conclusions and Outlook3.5.1 Distinct or Identical Functions for Phox2a and Phox2b?; 3.5.2 Master Control Genes for Noradrenergic Differentiation; 3.5.3 Master Control Genes for Autonomic Reflex Circuit Generation; Acknowledgments; Abbreviations; 4 Functions of LIM-Homeodomain Proteins in the Development of the Nervous System; Abstract; 4.1 Introduction; 4.2 Common Structural Features and Classification of LIM-HD Proteins; 4.3 LIM-HD Proteins and the Development of Invertebrate Nervous Systems; 4.3.1 C. elegans; 4.3.2 Drosophila 4.4 Functions of LIM-HD Proteins in the Development of Vertebrate Nervous Systems |
| Record Nr. | UNINA-9910144556803321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transcription factors in the nervous system [[electronic resource] ] : development, brain function and diseases / / edited by Gerald Thiel
| Transcription factors in the nervous system [[electronic resource] ] : development, brain function and diseases / / edited by Gerald Thiel |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (507 p.) |
| Disciplina | 616.8042 |
| Altri autori (Persone) | ThielGerald |
| Soggetto topico |
Transcription factors
Neural stem cells |
| ISBN |
1-280-85433-2
9786610854332 3-527-60803-6 3-527-60736-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Transcription Factors in the Nervous System; Contents; Preface; List of Contributors; Color Plates; Part I Transcription Factors in Neural Development; 1 Roles of Hes bHLH Factors in Neural Development; 1.1 Introduction; 1.2 Structure and Transcriptional Activities of Hes Factors; 1.3 Regulation of Hes Gene Expression; 1.4 Expression of Hes Genes in the Developing Nervous System; 1.5 Maintenance of Neural Stem Cells by Hes Genes; 1.6 Promotion of Gliogenesis by Hes Genes; 1.7 Maintenance of the Isthmic Organizer by Hes Genes; 1.8 Perspective; Acknowledgments; Abbreviations
2 The Role of Pax6 in the Nervous System during Development and in Adulthood: Master Control Regulator or Modular Function?Abstract; 2.1 Introduction; 2.2 Molecular Features of Pax6; 2.2.1 The Paired Domain; 2.2.2 The Paired-Type Homeodomain; 2.2.3 Different Pax6 Isoforms; 2.2.4 Protein-Protein Interactions; 2.2.5 Post-Translational Modifications of Pax6; 2.3 Function of Pax6 in Development; 2.3.1 Function of Pax6 in the Developing Eye; 2.3.2 Function of Pax6 in the Developing Brain; 2.3.2.1 Telencephalon; 2.3.2.2 Diencephalon; 2.3.2.3 Cerebellum; 2.3.2.4 Spinal Cord 2.4 Function of Pax6 in the Adult Brain2.5 Mechanisms of Pax6 Function; 2.6 Conclusions and Outlook; Abbreviations; 3 Phox2a and Phox2b: Essential Transcription Factors for Neuron Specification and Differentiation; Abstract; 3.1 Introduction; 3.2 Molecular Characteristics of Phox2 Genes and Proteins; 3.2.1 Sequence and Gene Structure Conservation in the Animal Kingdom; 3.2.2 Transcriptional Activation by Phox2 Proteins; 3.3 Physiological Relevance of Phox2 Transcription Factors; 3.3.1 Expression Pattern; 3.3.2 Effects of Phox2 Gene Mutations 3.3.2.1 Autonomic Neural Crest Derivatives and Visceral Sensory Ganglia3.3.2.2 Central Noradrenergic Neurons; 3.3.2.3 Autonomic Centers in the Hindbrain; 3.3.3 Human Mutations; 3.4 Molecular Mechanism of Action in Different Lineages; 3.4.1 Sympathetic Neurons; 3.4.2 Parasympathetic Neurons; 3.4.3 Enteric Neurons; 3.4.4 Visceral Sensory Neurons of the Geniculate, Petrosal and Nodose Ganglia; 3.4.5 Central Noradrenergic Neurons; 3.4.6 Autonomic Centers in the Hindbrain; 3.4.6.1 Afferent Visceral Centers; 3.4.6.2 Efferent Visceral Centers; 3.4.7 Oculomotor (nIII) and Trochlear (nIV) Centers 3.5 Conclusions and Outlook3.5.1 Distinct or Identical Functions for Phox2a and Phox2b?; 3.5.2 Master Control Genes for Noradrenergic Differentiation; 3.5.3 Master Control Genes for Autonomic Reflex Circuit Generation; Acknowledgments; Abbreviations; 4 Functions of LIM-Homeodomain Proteins in the Development of the Nervous System; Abstract; 4.1 Introduction; 4.2 Common Structural Features and Classification of LIM-HD Proteins; 4.3 LIM-HD Proteins and the Development of Invertebrate Nervous Systems; 4.3.1 C. elegans; 4.3.2 Drosophila 4.4 Functions of LIM-HD Proteins in the Development of Vertebrate Nervous Systems |
| Record Nr. | UNINA-9910830923603321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||