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Lipophilic Vitamins in Health and Disease
| Lipophilic Vitamins in Health and Disease |
| Autore | Tappia Paramjit S |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (411 pages) |
| Altri autori (Persone) |
ShahAnureet K
DhallaNaranjan S |
| Collana | Advances in Biochemistry in Health and Disease Series |
| ISBN | 3-031-55489-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- Contributors -- Part I General Aspects of Lipophilic Vitamins -- 1 The Cardio-protective Effect of Fat-Soluble Vitamins on Anti-cancer Drug Induced Cardiotoxicity -- Introduction -- Chemotherapy Drugs Inducing Possible Mitochondrial Damage -- Disruption to the Sarcomere Structure -- Vitamin D3's Cytoprotective Effect Through Various Signaling Pathway -- Synergistic Effect of Pirfenidone and Vitamin D -- Safety Efficacy of High-Dose Vitamin D Supplementation -- Synergistic Effect of Eicosapentaenoic Acid and Vitamin E -- Synergistic Effect of Hesperidin and Vitamin E -- Vitamin E's Protective Effect on Cisplatin Induced Cardiotoxicity -- Conclusion and Discussion -- Strengths and Limitations -- References -- 2 Fat Soluble Vitamins in the Ocular, Cardiac, and Infectious Diseases: Myths and Misconceptions -- Fat Soluble Vitamins -- The Role of Fat-Soluble Vitamins in Eye Health and Disease -- The Role of Fat-Soluble Vitamins in Cardiovascular Diseases (CVD) -- More Concentrations on Vitamin D -- Myths and Misconceptions About Fat-Soluble Vitamins -- Conclusions -- References -- 3 The Effects of Lipophilic Vitamins on Women's Heart Health -- Cardiovascular Disease in Women -- The Beneficial Effect of Vitamins a and D on Women's Heart Health -- Vitamin E and Women's Heart Health -- Vitamin K and Women's Heart Health -- Clinical Studies and Epidemiological Evidence of the Effect of Lipophilic Vitamins on Women's Heart Health -- Potential Risks and Considerations -- References -- 4 Mitigation of Dementia and Alzheimer's Disease with Lipophilic Vitamins and Their Derivatives: Preclinical and Clinical Evidence -- Introduction -- Overview of Pre-clinical Studies -- Supportive Evidence from Clinical Studies -- Nanotechnological Interventions in Promoting the Systemic Delivery of Vitamins.
Challenges and Opportunities in the Management of Neurodegenerative Diseases with Nanotechnology Delivery Systems -- References -- 5 Lipid-Soluble Vitamins: Their Roles in Cardiovascular Health and Diseases -- Introduction -- Vitamin A -- Overview -- Conversion of Carotenoids into Vitamin A -- Biochemical Reactions that Utilize Vitamin A -- Vitamin D -- Overview -- Biosynthesis of Vitamin D -- Biochemical Reactions -- Vitamin E -- Overview -- Biosynthesis -- Biochemical Reactions -- Vitamin K -- Overview -- Biosynthesis -- Biochemical Reactions and Cardiovascular Health -- Conclusion -- References -- 6 Interactions Between Gut Microbiota and Lipophilic Vitamins in Health and Disease -- Introduction -- Interactions of Fat-Soluble Vitamins with the Gut Microbiome to Maintain Physiological Homeostasis: Cellular and Molecular Insights -- Vitamin A -- Vitamin D -- Vitamin E -- Vitamin K -- Diseases Implicated for Gut Microbiome/lipophilic Vitamin Interaction Axis: A Pharmacological Overview -- Inflammatory Bowel Disease -- Neurological Complications -- Cancer Immunotherapy & -- Beyond -- Ageing -- Limitations in Current Understanding -- Future Perspectives -- Conclusion -- References -- Part II Vitamin E and Associated Metabolites in Health and Disease -- 7 The Potential Role of Tocotrienols Against Cardiovascular Diseases -- Introduction -- Structural and Chemical Differences Between Tocotrienol and Tocopherol Molecules that May Give Rise to Their Distinct Properties -- Dietary Sources -- Potential Role of Tocotrienols Against Cardiovascular Diseases: Inflammation and Immune Response -- Potential Role of Tocotrienols Against Cardiovascular Diseases: Cholesterol Metabolism and Homeostasis -- Concluding Remarks -- References -- 8 Recent Progress on the Skeletal Research of Tocotrienol -- Introduction -- Deposition of Tocotrienol in the Bone. Effects of Tocotrienol on Osteocytes and Wnt -- Effects of Tocotrienol on Mevalonate Pathway -- Effects of Tocotrienol on Bone in Humans -- Effects of Tocotrienol on Other Aspects of Bone Remodelling -- Research Gaps -- Conclusion -- References -- 9 Importance of Vitamin E and Its Metabolism for Health and Disease -- Introduction -- Metabolism of Vitamin E -- Diseases with Vitamin E Relevance -- Ataxia with Vitamin E Deficiency -- Cardiovascular Diseases -- Non-alcoholic Fatty Liver Disease -- Skin Health and Atopic Diseases -- Conclusions and Outlook -- References -- 10 Beneficial Effects of Vitamin E Combined with Antioxidants in Cardiovascular System Disorders: Experimental Evidence -- Introduction -- Metabolism and Functions of Vitamin E -- Vitamin E: Action in the Cell Membrane and Interaction with Intracellular Binding Proteins -- Vitamin E and Cardiovascular Function -- Beneficial Effects of Combined Treatment with Vitamin E and Other Antioxidants in the Cardiovascular System -- Conclusions -- References -- 11 Vitamin E for the Prevention and Treatment of Cardiovascular Disease -- Introduction -- Antioxidant Mechanism of Action of Vitamin E -- Vitamin E in Different Types of CVD -- Consideration for Other Classes of Vitamin E in CVD -- Role of Vitamin E in CVD in Diabetes -- Conclusion -- References -- 12 Vitamin E (Tocopherol): Implications in Cardiovascular Health and Neuroprotection -- Introduction -- Tocopherol Versus Tocotrienols -- Vitamin E as a Cofactor/Co-Enzyme in Various Metabolism -- Vitamin E-as an Antioxidant Property Against Lipid Peroxidation -- Scavenging Avenger of Vitamin E -- Vitamin E in Cell Membrane Protection -- Vitamin E in Primary Cardiac Prevention -- Vitamin E in Secondary RCT -- Vitamin E in Cardiac Muscle Recovery. Vitamin E-as a Neurodegenerative Agent and in Randomized Clinical Trials of Various Neurodegenerative Diseases -- Alzheimer's Diseases-Aging -- Pathogenesis of AD -- Proofs that Oxidative Damage Induced Damage of the Brain in AD Patients -- Vitamin-E Against AD -- Vitamin E in AD-Induced Animal Experimentation -- Clinical Trials with Vitamin E in AD Patients -- Neuroplasticity -- Parkinson's Disease -- Seizure's -- Purkinje Neurons Versus Vit-E -- Conclusion -- References -- Part III Functional Aspects of Vitamins A, D and K -- 13 Retinoids and the Vitamin a Receptor STRA6 in Health and Disease -- Introduction: The Importance of Vitamin a -- Vitamin a Metabolism -- Retinoid Signalling -- Retinoids in Cancer -- Retinoids in Development -- Retinoids in Skin -- STRA6 as the Receptor for RBP -- STRA6 in Disease (I): The Mathew Wood Syndrome -- STRA6 in Disease (II): Cancer -- STRA6 in Disease (III): Insulin Resistance -- Conclusions -- References -- 14 A Vitamin Treatment for Motor Neurone Disease -- Introduction -- Amyotrophic Lateral Sclerosis -- Retinoic Acid and the Retinoic Acid Receptor -- Retinoids as a Potential Therapeutic for Amyotrophic Lateral Sclerosis -- Conclusions -- References -- 15 Vitamin D and Its Role on Inflammation, Oxidative Stress and Cardiovascular Disease -- Introduction -- Vitamin D -- Biosynthesis -- Mechanism of Action -- Oxidative Stress, Inflammation and Cardiovascular Conditions -- Vitamin D, Inflammation and Oxidative Stress -- Vitamin D and Cardiovascular Risk -- Conclusion -- References -- 16 Vitamin D and Immune Function: Unraveling the Connections -- Introduction -- Vitamin D and Health -- Recommended Levels of Vitamin D -- Vitamin D and Immunity -- Vitamin D and Immune Cells -- Vitamin D and the Innate Immune System -- Vitamin D and the Adaptive Immune System. Vitamin D and Its Connection in Autoimmune Diseases and Immune-Related Disorders -- Type I Diabetes (TID) -- Psoriasis -- Multiple Sclerosis (MS) -- Rheumatoid Arthritis (RA) -- Systemic Lupus Erythematosus (SLE) -- Miscellaneous -- Conclusion -- Conflicts of Interest -- References -- 17 Maternal Vitamin D Levels During Gestation and Impact on Offspring's Risk of Non-communicable Diseases in Adulthood -- Background -- Why Vitamin D Matters? -- Vitamin D Level During Pregnancy and Infancy -- Vitamin D Effect on Fetal Growth and Neonatal Anthropomorphic Features -- Vitamin D Effect on Immune Response During Pregnancy -- Vitamin D Level During Adolescence -- Maternal Vitamin D Deficiency and Risk of Communicable Disease in Adulthood -- Vitamin D Metabolism During Pregnancy -- Vitamin D Supplementation During Gestation -- Fetal Programming and Vitamin D -- Conclusion -- References -- 18 Unveiling the Link of Vitamin D and Diverse Cardiovascular Disorders: Current Status and Future Prospective -- Introduction -- Vitamin D: Its Physiological Role and Deficiency -- Link Between Vitamin D and Various Cardiovascular Disorders -- Role of Vitamin D in Cardiomyopathy -- Role of Vitamin D in Pulmonary Arterial Hypertension -- Role of Vitamin D in Myocardial Infarction -- Role of Vitamin D in Cardiac Fibrosis and Remodeling -- Role of Vitamin D in Heart Failure -- Role of Vitamin D in Arrhythmias -- Role of Vitamin D in Endothelial Dysfunction -- Role of Vitamin D in Other Disorders -- Major Challenges and Future Directions -- Conclusion -- References -- 19 Environmental Pollution-Induced Vitamin D Deficiency and Its Impact on the Outcomes of Pregnancy -- Introduction -- Vitamin D -- Vitamin D Synthesis and Metabolism -- Vitamin D Metabolism in Pregnant Women -- Vitamin D and Calcium Metabolism in Pregnancy -- Physiological Effects Concerning Calcium and Phosphate. Environmental Pollution and Vitamin D Deficiency During Pregnancy. |
| Record Nr. | UNINA-9910857781403321 |
Tappia Paramjit S
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition and Cardiovascular Health
| Nutrition and Cardiovascular Health |
| Autore | Tappia Paramjit S |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (278 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
magnesium deficiency
arterial hypertension vascular tone arterial stiffness vascular remodeling insulin resistance magnesium supplementation dietary magnesium intake Zeb2 cardiac fibroblast activated myofibroblast cardiac fibrosis fibroblast contractility fish oil omega-3 fatty acids eicosapentaenoic acid (EPA) docosahexaenoic acid (DHA) cardiovascular disease irisin pediatric children nutrition diet body composition metabolic syndrome obesity, neonates Mediterranean diet inflammation nutrients polyphenols MUFA PUFA bioactive compounds phytosterols dietary pattern Aronia melanocarpa standardized extract dietary strategies supplementation cocaine cardiovascular health heart disease acute effects chronic effects marinobufagenin ouabain salt hypertension fibrosis Panax quinquefolius ginseng berry myocardial infarction phenolic compounds vascular aging vascular calcification arteriosclerosis Klotho chronic kidney disease (CKD), cancer diabetes heart failure micronutrients iron vitamins trace elements vitamin D seasonal variation lifestyle cytokines lipids mechanisms immunoregulatory eicosapentaenoic acid docosahexaenoic acid omega-3 polyunsaturated fatty acids coronary heart disease stretching TGF-β1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557641803321 |
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Tappia Paramjit S
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||