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Applied biocatalysis : the chemist's enzyme toolbox / / edited by John Whittall, Peter W. Sutton
| Applied biocatalysis : the chemist's enzyme toolbox / / edited by John Whittall, Peter W. Sutton |
| Pubbl/distr/stampa | Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , [2021] |
| Descrizione fisica | 1 online resource (xviii, 540 pages) : illustrations |
| Disciplina | 660.2995 |
| Soggetto topico | Biocatalysis |
| ISBN |
1-119-48703-X
1-5231-3729-0 1-119-48702-1 1-119-48704-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910555168703321 |
| Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Applied biocatalysis : the chemist's enzyme toolbox / / edited by John Whittall, Peter W. Sutton
| Applied biocatalysis : the chemist's enzyme toolbox / / edited by John Whittall, Peter W. Sutton |
| Pubbl/distr/stampa | Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , [2021] |
| Descrizione fisica | 1 online resource (xviii, 540 pages) : illustrations |
| Disciplina | 660.2995 |
| Soggetto topico | Biocatalysis |
| ISBN |
1-119-48703-X
1-5231-3729-0 1-119-48702-1 1-119-48704-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910830570403321 |
| Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Practical methods for biocatalysis and biotransformations . 3 / / edited by John Whittall, Manchester Interdisciplinary Biocentre (MIB), The University of Manchester, UK, Peter W. Sutton, GlaxoSmithKline Research and Development Limited, UK, Wolfgang Kroutil, Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Austria
| Practical methods for biocatalysis and biotransformations . 3 / / edited by John Whittall, Manchester Interdisciplinary Biocentre (MIB), The University of Manchester, UK, Peter W. Sutton, GlaxoSmithKline Research and Development Limited, UK, Wolfgang Kroutil, Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Austria |
| Edizione | [3.] |
| Pubbl/distr/stampa | Chichester, West Sussex : , : John Wiley & Sons, Limited, , 2016 |
| Descrizione fisica | 1 online resource (319 p.) |
| Disciplina | 660.6/34 |
| Soggetto topico |
Enzymes - Biotechnology
Biocatalysis Biotransformation (Metabolism) Organic compounds - Synthesis |
| ISBN |
1-5231-1471-1
1-118-69629-8 1-118-69628-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Practical Methods for Biocatalysis and Biotransformations 3; Contents; List of Contributors; Abbreviations; Chapter 1: Considerations for the Application of Process Technologies in Laboratory- and Pilot-Scale Biocatalysis for Chemical Synthesis; 1.1 Introduction; 1.2 Process Intensification and Proposed Scale-Up Concept; 1.3 Enabling Technologies; 1.3.1 Biocatalyst Immobilization; 1.3.1.1 General Considerations for Implementation; 1.3.1.2 Carrier-Bound Supported Enzymes; 1.3.1.2.1 Adsorption; Considerations for Implementation; 1.3.1.2.2 Covalent Binding; Considerations for Implementation
1.3.1.2.3 Ionic BindingConsiderations for Implementation; 1.3.1.3 Carrier-Free Immobilization; 1.3.1.3.1 Cross-Linked Enzyme Aggregates (CLEAsTM); Considerations for Implementation; 1.3.2 Reactor Options; 1.3.2.1 Ideal Reactors; 1.3.2.2 Modes of Operation; 1.3.2.3 Well-Mixed Reactor Hydrodynamics; 1.3.2.3.1 Stirred Tanks; Considerations for Implementation; 1.3.2.3.2 Batch Stirred-Tank Reactors (BSTRs); Considerations for Implementation; 1.3.2.3.3 Continuous Stirred-Tank Reactors (CSTRs); Considerations for Implementation; 1.3.2.3.4 Alternative Well-Mixed Reactors Continuous Fluidized-Bed Reactors (CFBRs)Considerations for Implementation; Continuous Packed-Bed Reactors (CPBRs); Considerations for Implementation; Continuous Expanded-Bed Reactors (CEBRs); Considerations for Implementation; 1.3.2.3.5 Membrane Bioreactors (MBRs); Considerations for Implementation; 1.4 Enhancing Technologies; 1.4.1 In Situ Product Removal (ISPR); 1.4.1.1 Considerations for Implementation; 1.4.1.2 ISPR by Adsorption on Resins; 1.4.1.2.1 Considerations for Implementation; 1.4.1.3 ISPR Using Expanded-Bed Adsorption (EBA); 1.4.1.3.1 Considerations for Implementation 1.4.1.4 ISPR by Crystallization1.4.1.4.1 Considerations for Implementation; 1.4.2 Substrate Feeding Strategies; 1.4.2.1 Fed-Batch Operation; 1.4.2.1.1 Considerations for Implementation; 1.4.3 Non-Conventional Media; 1.4.3.1 Single Non-Conventional Liquid Phase Systems; 1.4.3.1.1 Considerations for Implementation; 1.4.3.2 Aqueous-Organic Two-Liquid Phase Systems; 1.4.3.2.1 Considerations for Implementation; 1.4.3.3 Aqueous-Ionic Liquid Two-Liquid Phase Systems; 1.4.3.3.1 Considerations for Implementation; 1.4.4 Oxygen Supply Strategies; 1.4.4.1 Surface Aeration 1.4.4.1.1 Considerations for Implementation1.4.4.2 Sparged Aeration; 1.4.4.2.1 Considerations for Implementation; 1.4.4.3 Bubble-Column Reactors; 1.4.4.3.1 Considerations for Implementation; 1.5 Conclusion; References; Chapter 2: Cytochrome P450 (CYP) Progress in Biocatalysis for Synthetic Organic Chemistry; 2.1 Introduction; 2.2 CYP Development; 2.3 Recent Developments; 2.4 Conclusion; References; Chapter 3: Use of Hydrolases and Related Enzymes for Synthesis; 3.1 Continuous-Flow Reactor-Based Enzymatic Synthesis of Phosphorylated Compounds on a Large Scale; 3.1.1 Materials and Equipment 3.1.2 Immobilization of Acid Phosphatase on Immobeads |
| Record Nr. | UNINA-9910136419703321 |
| Chichester, West Sussex : , : John Wiley & Sons, Limited, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Practical methods for biocatalysis and biotransformations . 3 / / edited by John Whittall, Manchester Interdisciplinary Biocentre (MIB), The University of Manchester, UK, Peter W. Sutton, GlaxoSmithKline Research and Development Limited, UK, Wolfgang Kroutil, Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Austria
| Practical methods for biocatalysis and biotransformations . 3 / / edited by John Whittall, Manchester Interdisciplinary Biocentre (MIB), The University of Manchester, UK, Peter W. Sutton, GlaxoSmithKline Research and Development Limited, UK, Wolfgang Kroutil, Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Austria |
| Edizione | [3.] |
| Pubbl/distr/stampa | Chichester, West Sussex : , : John Wiley & Sons, Limited, , 2016 |
| Descrizione fisica | 1 online resource (319 p.) |
| Disciplina | 660.6/34 |
| Soggetto topico |
Enzymes - Biotechnology
Biocatalysis Biotransformation (Metabolism) Organic compounds - Synthesis |
| ISBN |
1-5231-1471-1
1-118-69629-8 1-118-69628-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Practical Methods for Biocatalysis and Biotransformations 3; Contents; List of Contributors; Abbreviations; Chapter 1: Considerations for the Application of Process Technologies in Laboratory- and Pilot-Scale Biocatalysis for Chemical Synthesis; 1.1 Introduction; 1.2 Process Intensification and Proposed Scale-Up Concept; 1.3 Enabling Technologies; 1.3.1 Biocatalyst Immobilization; 1.3.1.1 General Considerations for Implementation; 1.3.1.2 Carrier-Bound Supported Enzymes; 1.3.1.2.1 Adsorption; Considerations for Implementation; 1.3.1.2.2 Covalent Binding; Considerations for Implementation
1.3.1.2.3 Ionic BindingConsiderations for Implementation; 1.3.1.3 Carrier-Free Immobilization; 1.3.1.3.1 Cross-Linked Enzyme Aggregates (CLEAsTM); Considerations for Implementation; 1.3.2 Reactor Options; 1.3.2.1 Ideal Reactors; 1.3.2.2 Modes of Operation; 1.3.2.3 Well-Mixed Reactor Hydrodynamics; 1.3.2.3.1 Stirred Tanks; Considerations for Implementation; 1.3.2.3.2 Batch Stirred-Tank Reactors (BSTRs); Considerations for Implementation; 1.3.2.3.3 Continuous Stirred-Tank Reactors (CSTRs); Considerations for Implementation; 1.3.2.3.4 Alternative Well-Mixed Reactors Continuous Fluidized-Bed Reactors (CFBRs)Considerations for Implementation; Continuous Packed-Bed Reactors (CPBRs); Considerations for Implementation; Continuous Expanded-Bed Reactors (CEBRs); Considerations for Implementation; 1.3.2.3.5 Membrane Bioreactors (MBRs); Considerations for Implementation; 1.4 Enhancing Technologies; 1.4.1 In Situ Product Removal (ISPR); 1.4.1.1 Considerations for Implementation; 1.4.1.2 ISPR by Adsorption on Resins; 1.4.1.2.1 Considerations for Implementation; 1.4.1.3 ISPR Using Expanded-Bed Adsorption (EBA); 1.4.1.3.1 Considerations for Implementation 1.4.1.4 ISPR by Crystallization1.4.1.4.1 Considerations for Implementation; 1.4.2 Substrate Feeding Strategies; 1.4.2.1 Fed-Batch Operation; 1.4.2.1.1 Considerations for Implementation; 1.4.3 Non-Conventional Media; 1.4.3.1 Single Non-Conventional Liquid Phase Systems; 1.4.3.1.1 Considerations for Implementation; 1.4.3.2 Aqueous-Organic Two-Liquid Phase Systems; 1.4.3.2.1 Considerations for Implementation; 1.4.3.3 Aqueous-Ionic Liquid Two-Liquid Phase Systems; 1.4.3.3.1 Considerations for Implementation; 1.4.4 Oxygen Supply Strategies; 1.4.4.1 Surface Aeration 1.4.4.1.1 Considerations for Implementation1.4.4.2 Sparged Aeration; 1.4.4.2.1 Considerations for Implementation; 1.4.4.3 Bubble-Column Reactors; 1.4.4.3.1 Considerations for Implementation; 1.5 Conclusion; References; Chapter 2: Cytochrome P450 (CYP) Progress in Biocatalysis for Synthetic Organic Chemistry; 2.1 Introduction; 2.2 CYP Development; 2.3 Recent Developments; 2.4 Conclusion; References; Chapter 3: Use of Hydrolases and Related Enzymes for Synthesis; 3.1 Continuous-Flow Reactor-Based Enzymatic Synthesis of Phosphorylated Compounds on a Large Scale; 3.1.1 Materials and Equipment 3.1.2 Immobilization of Acid Phosphatase on Immobeads |
| Record Nr. | UNINA-9910830413303321 |
| Chichester, West Sussex : , : John Wiley & Sons, Limited, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Practical methods for biocatalysis and biotransformations 2 [[electronic resource] /] / edited by John Whittall, Peter W. Sutton
| Practical methods for biocatalysis and biotransformations 2 [[electronic resource] /] / edited by John Whittall, Peter W. Sutton |
| Edizione | [2] |
| Pubbl/distr/stampa | Hoboken, : John Wiley & Sons Inc., 2012 |
| Descrizione fisica | 1 online resource (390 p.) |
| Disciplina | 572 |
| Altri autori (Persone) |
WhittallJohn
SuttonPeter (Peter W.) |
| Soggetto topico |
Enzymes - Biotechnology
Biotransformation (Metabolism) Organic compounds - Synthesis |
| ISBN |
1-118-30786-0
1-280-59181-1 9786613621641 1-118-30785-2 1-119-94342-6 1-119-94341-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
PRACTICAL METHODS FOR BIOCATALYSIS AND BIOTRANSFORMATIONS 2; Contents; List of Contributors; Abbreviations; 1 Biocatalysis in the Fine Chemical and Pharmaceutical Industries; 1.1 Introduction; 1.2 Biotrans Outsourcing - AstraZeneca; 1.3 Biotrans Trends - Lonza; 1.4 Biocatalysis in the Pharma Environment; 1.5 Industrial Use of Hydrolases; 1.6 Industrial Biooxidation and Reduction; 1.7 Industrial Application of Transaminases - Cambrex; 1.8 Biocatalyst Discovery and Improvement; 1.9 From Pathway Engineering to Synthetic Biology
1.10 Prioritization of Future Biocatalysis and Synthetic Biology Needs1.11 Concluding Remarks; Acknowledgements; References; 2 Reductive Amination; 2.1 ?-Transaminases - Useful Biocatalysts for Chiral Amine Synthesis; 2.2 Preparative Scale Production of a Bulky-Bulky Chiral Amine Using an Engineered Transaminase; 2.3 Synthesis of Optically Pure Amines Employing ?-Transaminases; 2.4 A Fast, Sensitive Assay and Scale-Up of ?-Transaminase Catalysed Reactions; 2.5 Asymmetric Synthesis of L-3-Hydroxyadamantylglycine Using Branched Chain Aminotransferase 2.6 Asymmetric Reduction of Aryl Imines Using Candida parapsilosis ATCC 73303 Enoate Reductases for Reduction of Electron Deficient Alkenes; 3.1 Asymmetric Bioreduction of Activated Alkenes Using Ene-Reductases from the Old Yellow Enzyme Family; 3.2 Efficient Baker's Yeast Mediated Reduction with Substrate Feeding Product Removal (SFPR) Technology: Synthesis of (S)-2-Alkoxy-3-Aryl-1-Propanols; 3.3 Asymmetric Reduction of (4S)-(+)-Carvone Catalyzed by Enoate Reductases (ERs) Expressed by Non-Conventional Yeast (NCY) Whole Cells 3.4 Preparation of Enantiomerically Pure Citronellal Enantiomers Using Alkene Reductases3.5 Highly Enantiomeric Hydrogenation of C-C Double Bond of Methylated N-Phenyl and N-Phenylalkylmaleimides by Aspergillus fumigatus; 4 Industrial Carbonyl Reduction; 4.1 Bioreduction Using Immobilized Carbonyl Reductase Technology; 4.2 Preparative Ketoreductase-Catalyzed Kinetic Resolution of a Racemic Aldehyde; 4.3 Enzymatic Reduction of 2,6-dichloro-3-fluoro-acetophenone to Produce (S)-1-(2,6-dichloro-3-fluorophenyl)ethanol 4.4 Preparative Scale Production of Poorly Soluble Chiral Alcohol Intermediate for Montelukast5 Regio- and Stereoselective Hydroxylation; 5.1 Engineering of an Amycolatopsis orientalis P450 Compactin Hydroxylase into a Pravastatin Synthase by Changing the Stereospecificity of the Enzyme; 5.2 Recombinant Human Cytochrome P450 Enzymes Expressed in Escherichia coli as Whole Cell Biocatalysts: Preparative Synthesis of Oxidized Metabolites of an mGlu5 Receptor Antagonist; 5.3 Alpha-Keto Biooxidation Using Cunninghamella echinulata (DSM 63356) 5.4 Aromatic Hydroxylation: Preparation of 3,4-Dihydroxyphenylacetic Acid |
| Record Nr. | UNINA-9910790281503321 |
| Hoboken, : John Wiley & Sons Inc., 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Practical methods for biocatalysis and biotransformations 2 / / edited by John Whittall, Peter W. Sutton
| Practical methods for biocatalysis and biotransformations 2 / / edited by John Whittall, Peter W. Sutton |
| Edizione | [2] |
| Pubbl/distr/stampa | Hoboken, : John Wiley & Sons Inc., 2012 |
| Descrizione fisica | 1 online resource (390 p.) |
| Disciplina | 572 |
| Altri autori (Persone) |
WhittallJohn
SuttonPeter (Peter W.) |
| Soggetto topico |
Enzymes - Biotechnology
Biotransformation (Metabolism) Organic compounds - Synthesis |
| ISBN |
1-118-30786-0
1-280-59181-1 9786613621641 1-118-30785-2 1-119-94342-6 1-119-94341-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
PRACTICAL METHODS FOR BIOCATALYSIS AND BIOTRANSFORMATIONS 2; Contents; List of Contributors; Abbreviations; 1 Biocatalysis in the Fine Chemical and Pharmaceutical Industries; 1.1 Introduction; 1.2 Biotrans Outsourcing - AstraZeneca; 1.3 Biotrans Trends - Lonza; 1.4 Biocatalysis in the Pharma Environment; 1.5 Industrial Use of Hydrolases; 1.6 Industrial Biooxidation and Reduction; 1.7 Industrial Application of Transaminases - Cambrex; 1.8 Biocatalyst Discovery and Improvement; 1.9 From Pathway Engineering to Synthetic Biology
1.10 Prioritization of Future Biocatalysis and Synthetic Biology Needs1.11 Concluding Remarks; Acknowledgements; References; 2 Reductive Amination; 2.1 ?-Transaminases - Useful Biocatalysts for Chiral Amine Synthesis; 2.2 Preparative Scale Production of a Bulky-Bulky Chiral Amine Using an Engineered Transaminase; 2.3 Synthesis of Optically Pure Amines Employing ?-Transaminases; 2.4 A Fast, Sensitive Assay and Scale-Up of ?-Transaminase Catalysed Reactions; 2.5 Asymmetric Synthesis of L-3-Hydroxyadamantylglycine Using Branched Chain Aminotransferase 2.6 Asymmetric Reduction of Aryl Imines Using Candida parapsilosis ATCC 73303 Enoate Reductases for Reduction of Electron Deficient Alkenes; 3.1 Asymmetric Bioreduction of Activated Alkenes Using Ene-Reductases from the Old Yellow Enzyme Family; 3.2 Efficient Baker's Yeast Mediated Reduction with Substrate Feeding Product Removal (SFPR) Technology: Synthesis of (S)-2-Alkoxy-3-Aryl-1-Propanols; 3.3 Asymmetric Reduction of (4S)-(+)-Carvone Catalyzed by Enoate Reductases (ERs) Expressed by Non-Conventional Yeast (NCY) Whole Cells 3.4 Preparation of Enantiomerically Pure Citronellal Enantiomers Using Alkene Reductases3.5 Highly Enantiomeric Hydrogenation of C-C Double Bond of Methylated N-Phenyl and N-Phenylalkylmaleimides by Aspergillus fumigatus; 4 Industrial Carbonyl Reduction; 4.1 Bioreduction Using Immobilized Carbonyl Reductase Technology; 4.2 Preparative Ketoreductase-Catalyzed Kinetic Resolution of a Racemic Aldehyde; 4.3 Enzymatic Reduction of 2,6-dichloro-3-fluoro-acetophenone to Produce (S)-1-(2,6-dichloro-3-fluorophenyl)ethanol 4.4 Preparative Scale Production of Poorly Soluble Chiral Alcohol Intermediate for Montelukast5 Regio- and Stereoselective Hydroxylation; 5.1 Engineering of an Amycolatopsis orientalis P450 Compactin Hydroxylase into a Pravastatin Synthase by Changing the Stereospecificity of the Enzyme; 5.2 Recombinant Human Cytochrome P450 Enzymes Expressed in Escherichia coli as Whole Cell Biocatalysts: Preparative Synthesis of Oxidized Metabolites of an mGlu5 Receptor Antagonist; 5.3 Alpha-Keto Biooxidation Using Cunninghamella echinulata (DSM 63356) 5.4 Aromatic Hydroxylation: Preparation of 3,4-Dihydroxyphenylacetic Acid |
| Record Nr. | UNINA-9910825476803321 |
| Hoboken, : John Wiley & Sons Inc., 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||