Blockchain with Artificial Intelligence for Healthcare : A Synergistic Approach
| Blockchain with Artificial Intelligence for Healthcare : A Synergistic Approach |
| Autore | Malviya Rishabha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Bristol : , : Institute of Physics Publishing, , 2023 |
| Descrizione fisica | 1 online resource (209 pages) |
| Disciplina | 610.285 |
| Altri autori (Persone) |
SinghArun Kumar
SundramSonali BalusamyBalamurugan KadrySeifedine |
| Collana | IOP Ebooks Series |
| ISBN | 0-7503-5841-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910915779203321 |
Malviya Rishabha
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| Bristol : , : Institute of Physics Publishing, , 2023 | ||
| Lo trovi qui: Univ. Federico II | ||
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Deep Learning for Targeted Treatments : Transformation in Healthcare
| Deep Learning for Targeted Treatments : Transformation in Healthcare |
| Autore | Malviya Rishabha |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2022 |
| Descrizione fisica | 1 online resource (458 pages) |
| Altri autori (Persone) |
GhineaGheorghita
DhanarajRajesh Kumar BalusamyBalamurugan SundramSonali |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-119-85798-8
1-119-85797-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Acknowledgement -- 1 Deep Learning and Site-Specific Drug Delivery: The Future and Intelligent Decision Support for Pharmaceutical Manufacturing Science -- 1.1 Introduction -- 1.2 Drug Discovery, Screening and Repurposing -- 1.3 DL and Pharmaceutical Formulation Strategy -- 1.3.1 DL in Dose and Formulation Prediction -- 1.3.2 DL in Dissolution and Release Studies -- 1.3.3 DL in the Manufacturing Process -- 1.4 Deep Learning Models for Nanoparticle-Based Drug Delivery -- 1.4.1 Nanoparticles With High Drug Delivery Capacities Using Perturbation Theory -- 1.4.2 Artificial Intelligence and Drug Delivery Algorithms -- 1.4.3 Nanoinformatics -- 1.5 Model Prediction for Site-Specific Drug Delivery -- 1.5.1 Prediction of Mode and a Site-Specific Action -- 1.5.2 Precision Medicine -- 1.6 Future Scope and Challenges -- 1.7 Conclusion -- References -- 2 Role of Deep Learning, Blockchain and Internet of Things in Patient Care -- 2.1 Introduction -- 2.2 IoT and WBAN in Healthcare Systems -- 2.2.1 IoT in Healthcare -- 2.2.2 WBAN -- 2.2.2.1 Key Features of Medical Networks in the Wireless Body Area -- 2.2.2.2 Data Transmission & -- Storage Health -- 2.2.2.3 Privacy and Security Concerns in Big Data -- 2.3 Blockchain Technology in Healthcare -- 2.3.1 Importance of Blockchain -- 2.3.2 Role of Blockchain in Healthcare -- 2.3.3 Benefits of Blockchain in Healthcare Applications -- 2.3.4 Elements of Blockchain -- 2.3.5 Situation Awareness and Healthcare Decision Support with Combined Machine Learning and Semantic Modeling -- 2.3.6 Mobile Health and Remote Monitoring -- 2.3.7 Different Mobile Health Application with Description of Usage in Area of Application -- 2.3.8 Patient-Centered Blockchain Mode -- 2.3.9 Electronic Medical Record -- 2.3.9.1 The Most Significant Barriers to Adoption Are.
2.3.9.2 Concern Regarding Negative Unintended Consequences of Technology -- 2.4 Deep Learning in Healthcare -- 2.4.1 Deep Learning Models -- 2.4.1.1 Recurrent Neural Networks (RNN) -- 2.4.1.2 Convolutional Neural Networks (CNN) -- 2.4.1.3 Deep Belief Network (DBN) -- 2.4.1.4 Contrasts Between Models -- 2.4.1.5 Use of Deep Learning in Healthcare -- 2.5 Conclusion -- 2.6 Acknowledgments -- References -- 3 Deep Learning on Site-Specific Drug Delivery System -- 3.1 Introduction -- 3.2 Deep Learning -- 3.2.1 Types of Algorithms Used in Deep Learning -- 3.2.1.1 Convolutional Neural Networks (CNNs) -- 3.2.1.2 Long Short-Term Memory Networks (LSTMs) -- 3.2.1.3 Recurrent Neural Networks -- 3.2.1.4 Generative Adversarial Networks (GANs) -- 3.2.1.5 Radial Basis Function Networks -- 3.2.1.6 Multilayer Perceptron -- 3.2.1.7 Self-Organizing Maps -- 3.2.1.8 Deep Belief Networks -- 3.3 Machine Learning and Deep Learning Comparison -- 3.4 Applications of Deep Learning in Drug Delivery System -- 3.5 Conclusion -- References -- 4 Deep Learning Advancements in Target Delivery -- 4.1 Introduction: Deep Learning and Targeted Drug Delivery -- 4.2 Different Models/Approaches of Deep Learning and Targeting Drug -- 4.3 QSAR Model -- 4.3.1 Model of Deep Long-Term Short-Term Memory -- 4.3.2 RNN Model -- 4.3.3 CNN Model -- 4.4 Deep Learning Process Applications in Pharmaceutical -- 4.5 Techniques for Predicting Pharmacotherapy -- 4.6 Approach to Diagnosis -- 4.7 Application -- 4.7.1 Deep Learning in Drug Discovery -- 4.7.2 Medical Imaging and Deep Learning Process -- 4.7.3 Deep Learning in Diagnostic and Screening -- 4.7.4 Clinical Trials Using Deep Learning Models -- 4.7.5 Learning for Personalized Medicine -- 4.8 Conclusion -- Acknowledgment -- References -- 5 Deep Learning and Precision Medicine: Lessons to Learn for the Preeminent Treatment for Malignant Tumors. 5.1 Introduction -- 5.2 Role of DL in Gene Identification, Unique Genomic Analysis, and Precise Cancer Diagnosis -- 5.2.1 Gene Identification and Genome Data -- 5.2.2 Image Diagnosis -- 5.2.3 Radiomics, Radiogenomics, and Digital Biopsy -- 5.2.4 Medical Image Analysis in Mammography -- 5.2.5 Magnetic Resonance Imaging -- 5.2.6 CT Imaging -- 5.3 DL in Next-Generation Sequencing, Biomarkers, and Clinical Validation -- 5.3.1 Next-Generation Sequencing -- 5.3.2 Biomarkers and Clinical Validation -- 5.4 DL and Translational Oncology -- 5.4.1 Prediction -- 5.4.2 Segmentation -- 5.4.3 Knowledge Graphs and Cancer Drug Repurposing -- 5.4.4 Automated Treatment Planning -- 5.4.5 Clinical Benefits -- 5.5 DL in Clinical Trials-A Necessary Paradigm Shift -- 5.6 Challenges and Limitations -- 5.7 Conclusion -- References -- 6 Personalized Therapy Using Deep Learning Advances -- 6.1 Introduction -- 6.2 Deep Learning -- 6.2.1 Convolutional Neural Networks -- 6.2.2 Autoencoders -- 6.2.3 Deep Belief Network (DBN) -- 6.2.4 Deep Reinforcement Learning -- 6.2.5 Generative Adversarial Network -- 6.2.6 Long Short-Term Memory Networks -- References -- 7 Tele-Health Monitoring Using Artificial Intelligence Deep Learning Framework -- 7.1 Introduction -- 7.2 Artificial Intelligence -- 7.2.1 Types of Artificial Intelligence -- 7.2.1.1 Machine Intelligence -- 7.2.1.2 Types of Machine Intelligence -- 7.2.2 Applications of Artificial Intelligence -- 7.2.2.1 Role in Healthcare Diagnostics -- 7.2.2.2 AI in Telehealth -- 7.2.2.3 Role in Structural Health Monitoring -- 7.2.2.4 Role in Remote Medicare Management -- 7.2.2.5 Predictive Analysis Using Big Data -- 7.2.2.6 AI's Role in Virtual Monitoring of Patients -- 7.2.2.7 Functions of Devices -- 7.2.2.8 Clinical Outcomes Through Remote Patient Monitoring -- 7.2.2.9 Clinical Decision Support. 7.2.3 Utilization of Artificial Intelligence in Telemedicine -- 7.2.3.1 Artificial Intelligence-Assisted Telemedicine -- 7.2.3.2 Telehealth and New Care Models -- 7.2.3.3 Strategy of Telecare Domain -- 7.2.3.4 Role of AI-Assisted Telemedicine in Various Domains -- 7.3 AI-Enabled Telehealth: Social and Ethical Considerations -- 7.4 Conclusion -- References -- 8 Deep Learning Framework for Cancer Diagnosis and Treatment -- 8.1 Deep Learning: An Emerging Field for Cancer Management -- 8.2 Deep Learning Framework in Diagnosis and Treatment of Cancer -- 8.3 Applications of Deep Learning in Cancer Diagnosis -- 8.3.1 Medical Imaging Through Artificial Intelligence -- 8.3.2 Biomarkers Identification in the Diagnosis of Cancer Through Deep Learning -- 8.3.3 Digital Pathology Through Deep Learning -- 8.3.4 Application of Artificial Intelligence in Surgery -- 8.3.5 Histopathological Images Using Deep Learning -- 8.3.6 MRI and Ultrasound Images Through Deep Learning -- 8.4 Clinical Applications of Deep Learning in the Management of Cancer -- 8.5 Ethical Considerations in Deep Learning-Based Robotic Therapy -- 8.6 Conclusion -- Acknowledgments -- References -- 9 Applications of Deep Learning in Radiation Therapy -- 9.1 Introduction -- 9.2 History of Radiotherapy -- 9.3 Principal of Radiotherapy -- 9.4 Deep Learning -- 9.5 Radiation Therapy Techniques -- 9.5.1 External Beam Radiation Therapy -- 9.5.2 Three-Dimensional Conformal Radiation Therapy (3D-CRT) -- 9.5.3 Intensity Modulated Radiation Therapy (IMRT) -- 9.5.4 Image-Guided Radiation Therapy (IGRT) -- 9.5.5 Intraoperative Radiation Therapy (IORT) -- 9.5.6 Brachytherapy -- 9.5.7 Stereotactic Radiosurgery (SRS) -- 9.6 Different Role of Deep Learning with Corresponding Role of Medical Physicist -- 9.6.1 Deep Learning in Patient Assessment -- 9.6.1.1 Radiotherapy Results Prediction. 9.6.1.2 Respiratory Signal Prediction -- 9.6.2 Simulation Computed Tomography -- 9.6.3 Targets and Organs-at-Risk Segmentation -- 9.6.4 Treatment Planning -- 9.6.4.1 Beam Angle Optimization -- 9.6.4.2 Dose Prediction -- 9.6.5 Other Role of Deep Learning in Corresponds with Medical Physicists -- 9.7 Conclusion -- References -- 10 Application of Deep Learning in Radiation Therapy -- 10.1 Introduction -- 10.2 Radiotherapy -- 10.3 Principle of Deep Learning and Machine Learning -- 10.3.1 Deep Neural Networks (DNN) -- 10.3.2 Convolutional Neural Network -- 10.4 Role of AI and Deep Learning in Radiation Therapy -- 10.5 Platforms for Deep Learning and Tools for Radiotherapy -- 10.6 Radiation Therapy Implementation in Deep Learning -- 10.6.1 Deep Learning and Imaging Techniques -- 10.6.2 Image Segmentation -- 10.6.3 Lesion Segmentation -- 10.6.4 Computer-Aided Diagnosis -- 10.6.5 Computer-Aided Detection -- 10.6.6 Quality Assurance -- 10.6.7 Treatment Planning -- 10.6.8 Treatment Delivery -- 10.6.9 Response to Treatment -- 10.7 Prediction of Outcomes -- 10.7.1 Toxicity -- 10.7.2 Survival and the Ability to Respond -- 10.8 Deep Learning in Conjunction With Radiomoic -- 10.9 Planning for Treatment -- 10.9.1 Optimization of Beam Angle -- 10.9.2 Prediction of Dose -- 10.10 Deep Learning's Challenges and Future Potential -- 10.11 Conclusion -- References -- 11 Deep Learning Framework for Cancer -- 11.1 Introduction -- 11.2 Brief History of Deep Learning -- 11.3 Types of Deep Learning Methods -- 11.4 Applications of Deep Learning -- 11.4.1 Toxicity Detection for Different Chemical Structures -- 11.4.2 Mitosis Detection -- 11.4.3 Radiology or Medical Imaging -- 11.4.4 Hallucination -- 11.4.5 Next-Generation Sequencing (NGS) -- 11.4.6 Drug Discovery -- 11.4.7 Sequence or Video Generation -- 11.4.8 Other Applications -- 11.5 Cancer -- 11.5.1 Factors. 11.5.1.1 Heredity. |
| Record Nr. | UNINA-9910595599103321 |
Malviya Rishabha
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| Newark : , : John Wiley & Sons, Incorporated, , 2022 | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Systems Using Quantum Computing
| Drug Delivery Systems Using Quantum Computing |
| Autore | Malviya Rishabha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2024 |
| Descrizione fisica | 1 online resource (476 pages) |
| Disciplina | 615.6028563843 |
| Altri autori (Persone) |
SundramSonali
MeenakshiDhanalekshmi Unnikrishnan |
| Soggetto topico |
Quantum computing
Drug delivery systems |
| ISBN |
9781394159338
1394159331 9781394159321 1394159323 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Series Page -- Title Page -- Copyright Page -- Dedication Page -- Contents -- Foreword -- Preface -- Acknowledgments -- Chapter 1 Quantum Computational Concepts and Approaches in Drug Discovery, Development and Delivery -- 1.1 Introduction -- 1.2 Algorithms and QC in Pharma -- 1.2.1 Algorithms -- 1.2.2 Supervised Learning -- 1.2.3 Unsupervised Learning -- 1.2.4 Multi-Task Neural Networks -- 1.2.5 Graph Convolution -- 1.3 Potential of QC in Drug Discovery -- 1.3.1 Target Recognition and Validation -- 1.3.2 Production and Validation of Hits -- 1.3.3 Lead Optimization -- 1.3.4 Clinical Trials -- 1.3.5 Linking and Generating Data -- 1.4 QC and Drug Delivery -- 1.5 QC in Drug Delivery Modalities -- 1.5.1 Computational Approach Towards Nano Particulate Drug Delivery -- 1.5.2 Computational Approach for Bone Drug Delivery -- 1.5.3 Computational Approach for Polymeric Drug Delivery -- 1.5.4 Computational Approach for Microsphere Drug Delivery -- 1.5.5 Computational Approach for Dendrimer-Based Drug Delivery -- 1.5.6 Computational Approach for Carbon Nanotube-Based Drug Delivery -- 1.6 QC Applications in Pharma Industry -- 1.7 Challenges or Prospects -- 1.8 Conclusion -- References -- Chapter 2 Quantum-Enabled Drug Discovery Process -- 2.1 Introduction -- 2.2 Usual Challenges in Drug Designing and Discovery -- 2.2.1 Commercial Challenge -- 2.2.2 Modification or Transitional Challenges -- 2.2.3 Unexplored Areas Under Classical Computational Techniques -- 2.3 Medicinal Chemistry Through Quantum Mechanics -- 2.3.1 Underappreciation of Chemical Interactions in Protein-Ligand Complexes -- 2.3.2 Non-Classical Hydrogen Bonding -- 2.3.3 π-π Stacking -- 2.3.4 Hydrophobic Bond Interactions -- 2.3.5 Coordination from Water -- 2.3.6 Explicit Water -- 2.3.7 Implicit Water -- 2.4 Interaction Analysis -- 2.4.1 Fragment Interaction Energy.
2.4.2 Binding Free Energy -- 2.4.3 Fragment Molecular Orbital (FMO) Process and Analysis -- 2.5 Geometric Optimization -- 2.5.1 Analyzing Gradients -- 2.6 GAMESS: A Computational Technique for Biochemical Simulations -- 2.6.1 Introduction to Biochemical Simulations -- 2.6.2 Parametrizing Quantum Mechanics Method for Simulations -- 2.6.3 Quantum Mechanics and Molecular Mechanics Associated with GAMESS -- 2.6.4 Introduction to QuanPol -- 2.6.5 QuanPol: Covalent Boundary Treatment -- 2.6.6 GO and Harmonic Vibration Frequency -- 2.6.7 Molecular Dynamics Simulation -- 2.6.8 Free Energy Perturbation (Deviation of Energy) Simulation -- 2.6.8.1 QuanPol Process Umbrella Sampling -- 2.6.8.2 QuanPol Process Thermodynamic Integration (TI) -- 2.6.9 Setting Up Valuation and Calculation -- 2.6.10 Molecular Modeling and Visualization Software -- 2.7 Conclusion -- References -- Chapter 3 Quantum Computing and Its Promise in Drug Discovery -- 3.1 Introduction -- 3.1.1 Need for Quantum Computing -- 3.2 Quantum Computing's Types, Applications, Generality, and Power -- 3.2.1 Quantum Annealer -- 3.2.2 Analog Quantum -- 3.2.3 Universal Quantum -- 3.3 Drug Discovery and Quantum Computing -- 3.3.1 A Brief History of Drug Discovery -- 3.3.2 Modern Drug Discovery -- 3.4 Role of Quantum Computing in Drug Discovery -- 3.5 Quantum Computing Methodology in Drug Discovery -- 3.5.1 Target Identification and Validation -- 3.5.2 Hit Generation and Validation -- 3.5.3 Lead Optimization -- 3.5.4 Data Linkage and Generation -- 3.5.5 Clinical Trials -- 3.5.6 Molecular Formations -- 3.6 Examples of Companies Using Quantum Theory to Accelerate Drug Discovery -- 3.6.1 Aqemia -- 3.6.2 Hafnium Labs -- 3.6.3 Kuano -- 3.6.4 Menten AI -- 3.6.5 Pharmacelera -- 3.6.6 PharmCADD -- 3.6.7 Polaris Quantum Biotech -- 3.6.8 ProteinQure -- 3.6.9 Riverlane -- 3.6.10 Roivant Discovery -- 3.6.11 XtalPi. 3.6.12 Zapata Computing -- 3.7 Advantages of Quantum Computing -- 3.8 Applications of Quantum Computing in Drug Discovery and Development -- 3.8.1 A Future View of QC and Drug Discovery -- 3.8.2 Current Developments in QC and Drug Discovery -- 3.9 Conclusion -- References -- Chapter 4 Exploring Nano-Based Therapeutics by Quantum Computational Modeling -- 4.1 Introduction to Nano-Based Therapeutics -- 4.2 Introduction to Quantum Computational Modeling with Respect to Nano-Based Therapeutics -- 4.2.1 Particle-Based Models -- 4.2.2 Continuum-Based Models -- 4.3 Exploration of Nano-Based Therapeutics -- 4.4 Design and Development of Nano-Based Therapeutics -- 4.4.1 Prediction of Solubility -- 4.4.2 Prediction of Permeability -- 4.4.3 Selection of Components and Optimization of Formulation of Nano-Based Therapeutics -- 4.4.3.1 Prediction of Therapeutic Loading -- 4.4.4 Prediction of Therapeutic Release or Leakage -- 4.4.5 Prediction of the Pharmacokinetic Profile of Nano-Based Therapeutics -- 4.4.5.1 Prediction of Absorption -- 4.4.5.2 Prediction of Distribution (Protein Corona Formation) -- 4.4.5.3 Prediction of Metabolism -- 4.4.5.4 Prediction of Excretion -- 4.4.6 Understanding Protein Corona Formation -- 4.4.7 Understanding the Interaction of Nanosized Carrying Objects with Bio-Membranes -- 4.4.8 Prediction of the Pharmacodynamic Profile of Nano-Based Therapeutics -- 4.4.9 Prediction of Adverse Drug Reactions and Nanotoxicity -- 4.4.10 Design of Target-Oriented Nano-Based Therapeutics -- 4.5 Conclusion -- References -- Chapter 5 Application of Quantum Computational Simulation in Drug Delivery Strategies with Carbon Nanotubes -- 5.1 Introduction -- 5.2 Properties of CNTs -- 5.2.1 Electrical Properties of CNTs -- 5.2.2 Elastro-Mechanical Properties of CNTs -- 5.2.3 Thermal Properties of CNTs -- 5.2.4 Optical Properties of CNTs. 5.3 Functionalization of CNTs -- 5.3.1 Covalent Functionalization -- 5.3.2 Noncovalent Functionalization of CNTs -- 5.3.3 Encapsulation Inside CNTs -- 5.3.4 "Defect" Functionalization -- 5.4 Significance of CNT in Drug Delivery -- 5.5 Overview of CNT-Based Drug Delivery -- 5.6 Pharmacokinetics of CNTs -- 5.6.1 Absorption -- 5.6.2 Distribution -- 5.6.3 Metabolism and Excretion -- 5.7 Biosafety of Carbon Nanotube -- 5.7.1 Mechanism of CNT Toxicity -- 5.7.2 Scenario to Bypass Carbon Nanotube Toxicity -- 5.8 Quantum Computational -- 5.8.1 Structure-Based Drug Design Methods (SBDD) -- 5.8.2 Ligand-Based Drug Design Methods (LBDD) -- 5.9 Various Simulation Approaches in Drug-CNTs Interaction -- 5.9.1 QM Approaches -- 5.9.1.1 Ab Initio Approach -- 5.9.1.2 Semiempirical Approach -- 5.9.1.3 Hartree-Fock (HF) Approach -- 5.9.2 Molecular Dynamics (MD) Approaches -- 5.9.3 Monte Carlo (MC) Simulation Approaches -- 5.9.4 Hybrid Approaches -- 5.9.4.1 MD and QM Approaches -- 5.9.4.2 MM and QM Approaches -- 5.10 Applications of Quantum Computational Methods -- 5.10.1 Applications of Quantum Computational Methods in DDS -- 5.10.2 Applications of Quantum Computational Methods in Nanobiosensors -- 5.11 Conclusion -- References -- Chapter 6 Quantum Computation Approach for Nanotechnology-Based Targeted Drug Delivery Systems -- 6.1 Introduction -- 6.2 The Types of Quantum Computers -- 6.2.1 Scalable Quantum Computers -- 6.2.2 Noisy Intermediate-Scale Quantum Devices -- 6.2.3 Analog Quantum Devices -- 6.3 Role of QC in Computer-Aided Drug Design -- 6.4 Development of Molecular Formulations -- 6.4.1 QC-Based Development of Nanocarriers -- 6.4.2 QC in Biosensor -- 6.4.3 QC-Based Targeted Drug Delivery -- 6.4.4 Target Identification -- 6.4.5 Target Validation -- 6.4.6 Identification of Hit and Its Validation -- 6.4.7 Optimization of Lead. 6.5 Data Generation, Interpretation, and Co-Relation -- 6.6 Role of QC in Clinical Trials -- 6.7 Future Prospects -- 6.8 Conclusion -- References -- Chapter 7 Role of Quantum Computing Simulations in Targeted Drug Delivery of Liposomes -- 7.1 Introduction -- 7.2 Liposomes -- 7.3 Liposome Classification -- 7.3.1 Based on Preparation Methods -- 7.3.2 Based on Compositional and Structural Characteristics -- 7.4 Methods of Liposome Preparation -- 7.5 Drug Loading Method -- 7.5.1 Passive Loading Technique -- 7.5.1.1 Sonication -- 7.5.1.2 French Pressure Cell -- 7.5.1.3 Freeze-Thawed Liposomes -- 7.5.1.4 Solvent Evaporation with Ether Injection -- 7.5.1.5 Alcohol Infusion -- 7.5.1.6 Method of Reverse Phase Evaporation -- 7.5.1.7 Removal of Non-Encapsulated Material with Detergent -- 7.5.2 Active Loading Technique -- 7.5.2.1 Pro-Liposome -- 7.5.2.2 Lyophilization -- 7.6 Newer Approaches to Liposomes -- 7.6.1 Stealth Liposomes (Improving Circulation Time) -- 7.6.2 Improving Elasticity (Transferosomes) -- 7.6.3 Ethosomes (Improving Skin Penetration) -- 7.6.4 Pharmacosomes (Improvement in Medication Delivery for Poorly Soluble Medicines) -- 7.6.5 Nebulized Liposomes and Stimuli-Responsive Liposomes -- 7.7 Quantum Computing -- 7.8 Computational Modeling for Drug Delivery Process -- 7.9 Correlation Between Quantum Computing Simulation and Targeted Delivery of Liposomes -- 7.10 Computational Simulation of Lipid Membranes -- 7.11 Properties Measured by Simulation -- 7.11.1 Mechanical and Structural Properties -- 7.11.2 Dynamic Properties -- 7.11.3 Molecule Permeation -- 7.12 Liposomal Drug Delivery System -- 7.13 Experimental Techniques and Role of Computational Simulation in Liposomal Drug Delivery System -- 7.13.1 Lipids Membrane -- 7.13.2 Size, Surface Charge, and Zeta Potential -- 7.13.3 Morphology and Lamellarity. 7.14 Computational Simulation Study of Liposomes. |
| Record Nr. | UNINA-9911019543303321 |
Malviya Rishabha
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| Newark : , : John Wiley & Sons, Incorporated, , 2024 | ||
| Lo trovi qui: Univ. Federico II | ||
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Engineered Biomaterials : Synthesis and Applications / / edited by Rishabha Malviya, Sonali Sundram
| Engineered Biomaterials : Synthesis and Applications / / edited by Rishabha Malviya, Sonali Sundram |
| Autore | Malviya Rishabha |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (623 pages) |
| Disciplina | 610.153 |
| Altri autori (Persone) | SundramSonali |
| Collana | Engineering Materials |
| Soggetto topico |
Medical physics
Biomaterials Biomedical engineering Nanobiotechnology Cancer - Treatment Nanoscience Medical Physics Biomedical Engineering and Bioengineering Cancer Therapy Nanophysics |
| ISBN |
9789819966981
9819966981 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Naturally Derived Biomaterials: Advances and Opportunities -- 2. Different Techniques of Genetic Engineering Used for the Development of Novel Biomaterials -- 3. Green methods for the development of bone and tissue engineering based biomaterials -- 4. Genetically Induced Biomaterial Advances in Medical Science -- 5. Biomimetic approach for biomaterials development. |
| Record Nr. | UNINA-9910766881303321 |
Malviya Rishabha
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Lo trovi qui: Univ. Federico II | ||
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Explainable and Responsible Artificial Intelligence in Healthcare
| Explainable and Responsible Artificial Intelligence in Healthcare |
| Autore | Malviya Rishabha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2025 |
| Descrizione fisica | 1 online resource (377 pages) |
| Altri autori (Persone) | SundramSonali |
| Soggetto topico |
Artificial intelligence - Medical applications
Medical ethics |
| ISBN |
9781394302444
1394302444 9781394302420 1394302428 9781394302437 1394302436 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover -- Series Page -- Title Page -- Copyright Page -- Contents -- Foreword -- Preface -- Chapter 1 Uncapping Explainable Artificial Intelligence–Centered Reinforcement Learning and Natural Language Processing in Smart Healthcare System -- 1.1 Introduction -- 1.1.1 XAI in Healthcare: Relevance and Overview -- 1.1.2 Importance of Explainability in AI -- 1.1.3 Role of Reinforcement Learning and NLP in Smart Healthcare -- 1.1.4 Objectives of the Chapter -- 1.1.5 Structure of the Chapter -- 1.2 XAI-Based Reinforcement Learning in Smart Healthcare Systems -- 1.3 Natural Language Processing in Smart Healthcare Systems -- 1.3.1 Applications of NLP in Healthcare Industry -- 1.3.1.1 Deidentification of Clinical Records -- 1.3.1.2 Medical Text Mining -- 1.3.1.3 Extraction of Medical Information -- 1.3.1.4 Text Data Management -- 1.3.1.5 Health Information Graph -- 1.4 Incorporation of XAI-Based RL and NLP -- 1.5 Synergies Between XAI, RL, and NLP in Healthcare -- 1.5.1 Rule-Based Systems -- 1.5.2 Bayesian Networks -- 1.5.3 Decision Trees -- 1.5.4 Deep Learning Models -- 1.5.5 Enhanced Trust -- 1.5.6 Improved Understanding |
| Record Nr. | UNINA-9911020467103321 |
Malviya Rishabha
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| Newark : , : John Wiley & Sons, Incorporated, , 2025 | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrating Nanorobotics with Biophysics for Cancer Treatment
| Integrating Nanorobotics with Biophysics for Cancer Treatment |
| Autore | Malviya Rishabha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Bristol : , : Institute of Physics Publishing, , 2024 |
| Descrizione fisica | 1 online resource (291 pages) |
| Altri autori (Persone) |
YadavDeepika
SundramSonali KadrySeifedine S VirkGurvinder |
| Collana | Biophysical Society-IOP Series |
| ISBN |
9780750360197
9780750360203 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Author biographies -- Rishabha Malviya -- Deepika Yadav -- Sonali Sundram -- Seifedine Kadry -- Gurvinder Singh Virk -- About the book -- Chapter Nanorobotics: materials, design, and technology -- 1.1 Introduction -- 1.2 Nanorobot design and development -- 1.3 Nanorobots designed for a broad spectrum of healthcare uses -- 1.4 The applications of nanorobots in the field of biomedicine -- 1.4.1 Microbiology -- 1.4.2 Cancer therapy using nanorobots -- 1.4.3 Biologically inspired nanorobots -- 1.4.4 The prospects of nanorobots for use in hematology -- 1.4.5 The neurosurgical prospects of nanorobots -- 1.5 The prospects of nanorobots for use in dentistry -- 1.6 The use of nanorobots in gene therapy -- 1.7 The biocompatibility and toxicity of nanorobots -- 1.8 Conclusions -- References and further reading -- Chapter Robotics and biophysics: technology advances and challenges in organic and inorganic domains -- 2.1 Introduction -- 2.2 An introduction to the use of robots in the field of biophysics -- 2.2.1 The importance of robots in the field of biophysical research -- 2.2.2 The possible application of robots in areas of biophysical investigation -- 2.2.3 Biophysical applications of robot-based systems -- 2.3 Technology advances of soft robotics in the organic domain -- 2.3.1 The applications of soft robots in medical and biological settings -- 2.3.2 Biomimetic design -- 2.3.3 The benefits of biomimetic design in biophysics -- 2.3.4 The challenges of applying biomimetic design principles in the field of biophysics -- 2.4 Developments in inorganic measurement technology -- 2.4.1 The integration of advanced prosthetic limbs and biophysics -- 2.4.2 Robotics in diagnostic imaging and laboratory tasks -- 2.5 Challenges in integration -- 2.5.1 Ethical and regulatory issues.
2.5.2 Regulatory challenges in the development of biophysics-based robotic systems -- 2.5.3 Interdisciplinary collaboration -- 2.6 Future prospects -- 2.7 Conclusions -- References -- Chapter Nanorobots: a primer for deciphering the biophysics of cancer -- 3.1 Introduction -- 3.2 Multiscale cancer biophysics -- 3.3 The biology of cancer cells -- 3.4 The reason for a biophysical strategy for cancer -- 3.5 Nanorobots -- 3.6 Nanorobots for the detection and treatment of cancer -- 3.7 Conclusions -- References and further reading -- Chapter The biophysics of cancer: management at the nanoscale -- 4.1 Introduction -- 4.2 Important aspects of nanorobots for cancer therapy -- 4.3 Nanorobot propulsion systems for anticancer medicine delivery -- 4.3.1 Nanorobots propelled by magnets -- 4.3.2 Nanorobots propelled by ultrasound -- 4.3.3 Biologically propelled nanorobots -- 4.3.4 Hybrid-drive nanorobots -- 4.3.5 Nanorobots propelled by other power sources -- 4.4 Precision cancer diagnosis and treatment with nanorobots -- 4.4.1 The identification and assessment of cancerous conditions -- 4.4.2 Gene therapy involving the precise administration of nucleic DNA -- 4.4.3 Vascular infarction in tumors -- 4.5 Nanorobots in cancer therapy: potential and clinical problems -- 4.5.1 The complexity and accuracy of the technology -- 4.5.2 Concerns regarding personal safety -- 4.5.3 Regulatory concerns -- 4.5.4 Scalability -- 4.5.5 Cost -- 4.5.6 Quality control -- 4.5.7 Management of the supply chain and its components -- 4.6 Future perspectives and conclusions -- References -- Chapter Magnetomechanical systems at the micro/nanoscale for cancer management -- 5.1 Introduction -- 5.2 Cancer therapy using magnetomechanical particles -- 5.2.1 Principle -- 5.3 The magnetomechanical identification of telomerase and nuclear acids in cancerous cells. 5.4 The therapeutic applications of telomerase studies in cancer -- 5.5 The clinical applications of telomeres and telomerase in oncology -- 5.6 Conclusions -- Funding -- Conflict of interest -- References -- Chapter The role of micro/nanorobotics in personalized healthcare -- 6.1 Introduction -- 6.2 Surgical operations -- 6.2.1 Biopsy and sample collection -- 6.2.2 The invasion or penetration of tissues -- 6.2.3 The breakdown of biofilms -- 6.2.4 Deliveries conducted within cells -- 6.3 Diagnosis -- 6.3.1 Biological sensors -- 6.3.2 Isolation -- 6.3.3 Physical sensors -- 6.4 Imaging and diagnostic medicine -- 6.4.1 Optical imaging -- 6.4.2 Imaging using ultrasound -- 6.4.3 Imaging using radionuclides -- 6.5 Prospective view -- 6.6 Regulatory challenges in personalized healthcare -- 6.7 Conclusions -- References and further reading -- Chapter The development of active nanorobots in personalized healthcare -- 7.1 Introduction -- 7.2 Nanorobots -- 7.3 Nanorobots in healthcare -- 7.3.1 Helices -- 7.3.2 Nanorods -- 7.3.3 DNA nanorobots -- 7.4 Applications of nanorobots in personalized healthcare -- 7.4.1 The use of nanorobots in dentistry -- 7.4.2 The use of nanorobots in cancer treatment -- 7.4.3 The application of nanorobots in the treatment and diagnosis of diabetes -- 7.4.4 The application of nanorobots in neurology -- 7.4.5 The application of nanorobots in hematology -- 7.5 Future perspectives -- 7.6 Conclusions -- References -- Chapter Nanozyme-based nanorobots for cancer treatment applications -- 8.1 Introduction -- 8.2 Nanomedicine and nanotheranostics -- 8.3 Targeted tumor vessel infarction with nanomedicine -- 8.4 Targeted tumor drug delivery systems -- 8.4.1 Passively targeted drug delivery systems -- 8.4.2 Actively targeted medication delivery systems -- 8.5 Micro- and nanorobots -- 8.5.1 Chemically powered micro- and nanorobots. 8.5.2 External-field-powered micro- and nanorobots -- 8.5.3 Biohybrid micro- and nanorobots -- 8.6 Difficulties with cancer nanomedicines -- 8.7 Future perspectives -- 8.8 Conclusions -- References -- Chapter Progress in the bioelectrochemical and biophysical diagnostic profiling of malignant cancer cells -- 9.1 Introduction -- 9.2 The use of biosensors in clinical assessment -- 9.3 Electrochemical biosensors -- 9.3.1 Various electrochemical measurement methods -- 9.4 Conventional apoptotic and metastatic cell detection methods -- 9.5 Bioelectricity in cancer processes -- 9.5.1 Cancer and ion channels -- 9.5.2 Calcium channels -- 9.5.3 Sodium channels -- 9.5.4 Intracellular potassium channels -- 9.5.5 Chloride channels -- 9.5.6 Piezoelectric channels -- 9.6 The detection of bioelectric characteristics -- 9.7 Bioelectrical modifications -- 9.8 Electrification and extracellular vesicles -- 9.9 Biosensors for in vitro cancer cell assessment -- 9.10 Conclusions -- References and further reading -- Chapter Wireless microrobots: the next frontier in medical advancements -- 10.1 Introduction -- 10.2 Microrobots and their potential therapeutic applications -- 10.2.1 The imaging of functional capabilities for disorder diagnosis -- 10.2.2 Mobile situational awareness for disease diagnosis and health management -- 10.3 Targeted therapy -- 10.4 The applications of microrobotics in medicine, particularly in the human cardiovascular system and the bloodstream -- 10.5 Biomechanical restrictions that impede microrobots -- 10.6 Current challenges facing miniaturized biomedical robots and their potential future applications -- 10.7 Methods for the actuation and control of therapeutic microrobots -- 10.8 Conclusions -- References and further reading -- Chapter Revolutionizing cancer treatment using micro/nanorobotic devices -- 11.1 Introduction. 11.2 Nano/microrobots for drug delivery -- 11.3 Cancer-targeted drug delivery systems -- 11.3.1 Enhancing treatment precision using passive drug delivery -- 11.3.2 Enhancing treatment precision using active drug targeting -- 11.3.3 Surgical advancements with micro/nanorobotic assistance -- 11.3.4 Robotic biosensing -- 11.3.5 Enhancing drug delivery with micro/nanorobot mobility -- 11.3.6 Field-guided micro/nanorobotics -- 11.4 Conclusions and prospects -- References and further reading -- Chapter Cyborgs and cyberorgans: biosecurity in biorobotics for healthcare-a case study -- 12.1 Introduction -- 12.2 Biorobotics in healthcare -- 12.3 Cyborgs and cyberorgans in healthcare -- 12.4 Case study -- 12.5 Patent list -- 12.6 Conclusions -- References. |
| Record Nr. | UNINA-9911026074003321 |
Malviya Rishabha
|
||
| Bristol : , : Institute of Physics Publishing, , 2024 | ||
| Lo trovi qui: Univ. Federico II | ||
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Integration of Biomaterials for Gene Therapy
| Integration of Biomaterials for Gene Therapy |
| Autore | Malviya Rishabha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2023 |
| Descrizione fisica | 1 online resource (435 pages) |
| Altri autori (Persone) |
SundramSonali
JainNeelam |
| ISBN |
1-394-17561-2
1-394-17563-9 1-394-17562-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Table of Contents -- Series Page -- Title Page -- Copyright Page -- Foreword -- Preface -- Acknowledgment -- 1 Biocompatible Hydrogels for Gene Therapy -- 1.1 Introduction -- 1.2 Hydrogels Classification -- 1.3 Fabrication of Hydrogels and Its Desirable Technical Features -- 1.4 Factors to be Tuned for Gene Encapsulation in Hydrogels -- 1.5 Recent Advances on Hydrogels for Gene Delivery -- 1.6 Conclusion -- References -- 2 Use of Polysaccharides -- 2.1 Introduction -- 2.2 Cross-Linking Techniques for Engineering Polysaccharides-Based Biomaterials -- 2.3 Approaches to Design Polysaccharide-Derived Biomaterials -- 2.4 Biomedical Applications of Polysaccharide-Derived Biomaterials -- 2.5 Advanced Biomaterials for Wound Dressings -- 2.6 Scaffolds for Tissue Engineering and Development of Bioinks for 3D Bioprinting -- 2.7 Recent Utilization of Polysaccharides -- 2.8 Toxicity Concerns of Polysaccharide-Derived Biomaterials -- 2.9 Preclinical and Clinical Studies on Gene Delivery Using Polysaccharide-Based Biomaterials -- 2.10 Challenges and Future Directions -- 2.11 Future Prospects -- 2.12 Conclusion -- References -- 3 Polysaccharide-Based Biomaterials for Gene Delivery -- 3.1 Background -- 3.2 Introduction -- 3.3 Gene Therapy -- 3.4 Gene Delivery Systems Based on Polysaccharides -- 3.5 Practical Application of Gene Delivery Systems -- 3.6 Polysaccharide-Based Nanoparticles -- 3.7 DNA Delivery -- 3.8 Conclusion -- References -- 4 Hydrogel-Based Gene Therapy -- 4.1 Introduction -- 4.2 Gene Therapy -- 4.3 In Vivo Gene Therapy Using Hydrogels -- 4.4 Encapsulating Cells in Hydrogels for Gene Therapy Delivery -- 4.5 Hydrogels for Integrative Tissue Engineering and Cell Delivery -- 4.6 Biocompatible Hydrogels for Transferring Cells -- 4.7 Using Hydrogels for Gene Therapy in Tissue Engineering-Based Drug.
4.8 Human Gene Therapy that Uses Hydrogel as an Alternative Method of Delivering Genetic Material to Patients -- 4.9 Recent Advancement in Biocompatible Hydrogel -- 4.10 Applications of Hydrogel -- 4.11 Current Hydrogels in Clinical Trials -- 4.12 Conclusions -- References -- 5 Progress and Prospects for Non-Viral Gene Therapy -- 5.1 Introduction -- 5.2 Definition -- 5.3 Technology Overview for Non-Viral Gene Delivery -- 5.4 Chemical Carriers for Gene Transfer: Establishing Effective In Vivo Gene Delivery -- 5.5 Types of Gene Delivery -- 5.6 Reduction of Immunological Responses Through Alteration of Delivery Method or DNA Structure -- 5.7 To Enable Long-Lasting Gene Expression, Self-Replicating, Tissue-Specific, and Integrating Plasmid Expression Systems are Designed -- 5.8 Hybrid Vector Systems to Improve Transfection and Lessen Cytotoxicity -- 5.9 Vehicle Material -- 5.10 Further Effects -- 5.11 Challenges and Prospects -- 5.12 Conclusion -- References -- 6 Nanoparticles for Tumor Gene Therapy -- 6.1 Introduction -- 6.2 Technologies for Gene Delivery -- 6.3 Cancer Treatment with Gene Therapy -- 6.4 Gene Therapy Using Nanotechnology -- 6.5 Challenges and Future Aspects -- References -- 7 Effective Gene Transfer with Non-Viral Vectors -- 7.1 Introduction -- 7.2 System Development for Delivering Genes -- 7.3 Methods for Non-Viral Vector for Delivery of Genes -- 7.4 Delivery System -- 7.5 Current Methods for Nonviral Gene Delivery: Benefits and Drawbacks -- 7.6 Current Barriers for Non-Viral Vectors -- 7.7 Possibilities for Enhancing the Non-Viral Vector Delivery System -- 7.8 Conclusion -- 7.9 Future Relevance -- References -- 8 Utilization of Chitosan for Gene Delivery -- 8.1 Introduction -- 8.2 Cationic Polymers-Based Gene Delivery Systems -- 8.3 Chitosan and Its Derivatives in Gene Delivery Systems -- 8.4 Chitosan as Chemotherapeutic Drugs. 8.5 Conclusion -- References -- 9 Nanoparticles as Gene Vectors in Tumor Therapy -- 9.1 Introduction -- 9.2 Polymer-Based Nanocarriers: Their Technology and Recent Advances -- 9.3 Conclusions -- References -- 10 Progress in Non-Viral Delivery of Nucleic Acid -- 10.1 Introduction -- 10.2 Physical Methods of Non-Viral Nucleic Acid Delivery System -- 10.3 Advantages and Disadvantages of Physical Transfection -- 10.4 Chemical Methods of Non-Viral Nucleic Acid Delivery System -- 10.5 Advantages and Disadvantages of Chemical Transfection -- 10.6 Cellular Barriers for Nucleic Acid Delivery Faced by Non-Viral Vectors -- 10.7 Challenges and Limitations of Non-Viral Nucleic Acid Delivery System -- 10.8 Conclusion -- References -- 11 The Junction of Biomaterials and Gene Therapy - Current Strategies and Future Directions -- 11.1 Introduction -- 11.2 Viral Gene Therapy -- 11.3 DNA Viral Vectors -- 11.4 Adeno-Associated Viral Vectors -- 11.5 Non-Viral Gene Therapy -- 11.6 Recent Advances in the Development of Gene Delivery Systems -- 11.7 Development of Gene Delivery Systems -- 11.8 Viral Vectors Based on DNA for Gene Delivery Systems -- 11.9 Viral Vectors Based on RNA for Gene Delivery Systems -- 11.10 Oncolytic Viral Vectors for Gene Delivery Systems -- 11.11 Practical Application of Gene Delivery Methods -- 11.12 Conclusion -- References -- 12 Utilization of Silk for Gene Delivery -- 12.1 Introduction -- 12.2 Dimensional Structure of Silk -- 12.3 Properties of Silk -- 12.4 Extraction of Fibroin from Silk Worm -- 12.5 Fabrication of Silk in Different Therapeutics Carriers -- 12.6 Utilization of Silk for Gene Therapy -- 12.7 Properties of Silk Fibroin as Biomaterial -- 12.8 Summary of Silk-Based Formulations for Gene Delivery [33] -- 12.9 Examples of Some Delivery Approaches which Utilizes Silk as a Biomaterial for Gene Delivery. 12.10 Some Highlights of Silk Fibroin -- 12.11 Conclusion -- References -- 13 Challenges and Emerging Problems in Nanomedicine Mediated Gene Therapy -- 13.1 Introduction -- 13.2 Why Nanomedicine Over Traditional Drugs? -- 13.3 Nanomedicine for Gene Therapy -- 13.4 Complications in Nanomedicine-Mediated Gene Therapy -- 13.5 Challenges in the Clinical Translation of Nanomedicines -- 13.6 Conclusion -- References -- 14 Biomaterials-Based Vaccination in Cancer Therapy -- 14.1 Introduction -- 14.2 Tumor-Associated Antigens -- 14.3 Vaccine Delivery -- 14.4 Dendritic Cells -- 14.5 In Vitro Generation of Dendritic Cells -- 14.6 Usage of RNA -- 14.7 RNA-Pulsed DCs as Vaccines -- 14.8 RNA Vaccines -- 14.9 Optimization of Immunotherapy -- 14.10 Cancer Treatment Through RNA Interference -- 14.11 Conclusion -- References -- Index -- End User License Agreement. |
| Record Nr. | UNINA-9910830598103321 |
Malviya Rishabha
|
||
| Newark : , : John Wiley & Sons, Incorporated, , 2023 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Integration of Biomaterials for Gene Therapy
| Integration of Biomaterials for Gene Therapy |
| Autore | Malviya Rishabha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2023 |
| Descrizione fisica | 1 online resource (435 pages) |
| Altri autori (Persone) |
SundramSonali
JainNeelam |
| Soggetto topico |
Gene therapy
Biomedical engineering |
| ISBN |
9781394175611
1394175612 9781394175635 1394175639 9781394175628 1394175620 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Table of Contents -- Series Page -- Title Page -- Copyright Page -- Foreword -- Preface -- Acknowledgment -- 1 Biocompatible Hydrogels for Gene Therapy -- 1.1 Introduction -- 1.2 Hydrogels Classification -- 1.3 Fabrication of Hydrogels and Its Desirable Technical Features -- 1.4 Factors to be Tuned for Gene Encapsulation in Hydrogels -- 1.5 Recent Advances on Hydrogels for Gene Delivery -- 1.6 Conclusion -- References -- 2 Use of Polysaccharides -- 2.1 Introduction -- 2.2 Cross-Linking Techniques for Engineering Polysaccharides-Based Biomaterials -- 2.3 Approaches to Design Polysaccharide-Derived Biomaterials -- 2.4 Biomedical Applications of Polysaccharide-Derived Biomaterials -- 2.5 Advanced Biomaterials for Wound Dressings -- 2.6 Scaffolds for Tissue Engineering and Development of Bioinks for 3D Bioprinting -- 2.7 Recent Utilization of Polysaccharides -- 2.8 Toxicity Concerns of Polysaccharide-Derived Biomaterials -- 2.9 Preclinical and Clinical Studies on Gene Delivery Using Polysaccharide-Based Biomaterials -- 2.10 Challenges and Future Directions -- 2.11 Future Prospects -- 2.12 Conclusion -- References -- 3 Polysaccharide-Based Biomaterials for Gene Delivery -- 3.1 Background -- 3.2 Introduction -- 3.3 Gene Therapy -- 3.4 Gene Delivery Systems Based on Polysaccharides -- 3.5 Practical Application of Gene Delivery Systems -- 3.6 Polysaccharide-Based Nanoparticles -- 3.7 DNA Delivery -- 3.8 Conclusion -- References -- 4 Hydrogel-Based Gene Therapy -- 4.1 Introduction -- 4.2 Gene Therapy -- 4.3 In Vivo Gene Therapy Using Hydrogels -- 4.4 Encapsulating Cells in Hydrogels for Gene Therapy Delivery -- 4.5 Hydrogels for Integrative Tissue Engineering and Cell Delivery -- 4.6 Biocompatible Hydrogels for Transferring Cells -- 4.7 Using Hydrogels for Gene Therapy in Tissue Engineering-Based Drug.
4.8 Human Gene Therapy that Uses Hydrogel as an Alternative Method of Delivering Genetic Material to Patients -- 4.9 Recent Advancement in Biocompatible Hydrogel -- 4.10 Applications of Hydrogel -- 4.11 Current Hydrogels in Clinical Trials -- 4.12 Conclusions -- References -- 5 Progress and Prospects for Non-Viral Gene Therapy -- 5.1 Introduction -- 5.2 Definition -- 5.3 Technology Overview for Non-Viral Gene Delivery -- 5.4 Chemical Carriers for Gene Transfer: Establishing Effective In Vivo Gene Delivery -- 5.5 Types of Gene Delivery -- 5.6 Reduction of Immunological Responses Through Alteration of Delivery Method or DNA Structure -- 5.7 To Enable Long-Lasting Gene Expression, Self-Replicating, Tissue-Specific, and Integrating Plasmid Expression Systems are Designed -- 5.8 Hybrid Vector Systems to Improve Transfection and Lessen Cytotoxicity -- 5.9 Vehicle Material -- 5.10 Further Effects -- 5.11 Challenges and Prospects -- 5.12 Conclusion -- References -- 6 Nanoparticles for Tumor Gene Therapy -- 6.1 Introduction -- 6.2 Technologies for Gene Delivery -- 6.3 Cancer Treatment with Gene Therapy -- 6.4 Gene Therapy Using Nanotechnology -- 6.5 Challenges and Future Aspects -- References -- 7 Effective Gene Transfer with Non-Viral Vectors -- 7.1 Introduction -- 7.2 System Development for Delivering Genes -- 7.3 Methods for Non-Viral Vector for Delivery of Genes -- 7.4 Delivery System -- 7.5 Current Methods for Nonviral Gene Delivery: Benefits and Drawbacks -- 7.6 Current Barriers for Non-Viral Vectors -- 7.7 Possibilities for Enhancing the Non-Viral Vector Delivery System -- 7.8 Conclusion -- 7.9 Future Relevance -- References -- 8 Utilization of Chitosan for Gene Delivery -- 8.1 Introduction -- 8.2 Cationic Polymers-Based Gene Delivery Systems -- 8.3 Chitosan and Its Derivatives in Gene Delivery Systems -- 8.4 Chitosan as Chemotherapeutic Drugs. 8.5 Conclusion -- References -- 9 Nanoparticles as Gene Vectors in Tumor Therapy -- 9.1 Introduction -- 9.2 Polymer-Based Nanocarriers: Their Technology and Recent Advances -- 9.3 Conclusions -- References -- 10 Progress in Non-Viral Delivery of Nucleic Acid -- 10.1 Introduction -- 10.2 Physical Methods of Non-Viral Nucleic Acid Delivery System -- 10.3 Advantages and Disadvantages of Physical Transfection -- 10.4 Chemical Methods of Non-Viral Nucleic Acid Delivery System -- 10.5 Advantages and Disadvantages of Chemical Transfection -- 10.6 Cellular Barriers for Nucleic Acid Delivery Faced by Non-Viral Vectors -- 10.7 Challenges and Limitations of Non-Viral Nucleic Acid Delivery System -- 10.8 Conclusion -- References -- 11 The Junction of Biomaterials and Gene Therapy - Current Strategies and Future Directions -- 11.1 Introduction -- 11.2 Viral Gene Therapy -- 11.3 DNA Viral Vectors -- 11.4 Adeno-Associated Viral Vectors -- 11.5 Non-Viral Gene Therapy -- 11.6 Recent Advances in the Development of Gene Delivery Systems -- 11.7 Development of Gene Delivery Systems -- 11.8 Viral Vectors Based on DNA for Gene Delivery Systems -- 11.9 Viral Vectors Based on RNA for Gene Delivery Systems -- 11.10 Oncolytic Viral Vectors for Gene Delivery Systems -- 11.11 Practical Application of Gene Delivery Methods -- 11.12 Conclusion -- References -- 12 Utilization of Silk for Gene Delivery -- 12.1 Introduction -- 12.2 Dimensional Structure of Silk -- 12.3 Properties of Silk -- 12.4 Extraction of Fibroin from Silk Worm -- 12.5 Fabrication of Silk in Different Therapeutics Carriers -- 12.6 Utilization of Silk for Gene Therapy -- 12.7 Properties of Silk Fibroin as Biomaterial -- 12.8 Summary of Silk-Based Formulations for Gene Delivery [33] -- 12.9 Examples of Some Delivery Approaches which Utilizes Silk as a Biomaterial for Gene Delivery. 12.10 Some Highlights of Silk Fibroin -- 12.11 Conclusion -- References -- 13 Challenges and Emerging Problems in Nanomedicine Mediated Gene Therapy -- 13.1 Introduction -- 13.2 Why Nanomedicine Over Traditional Drugs? -- 13.3 Nanomedicine for Gene Therapy -- 13.4 Complications in Nanomedicine-Mediated Gene Therapy -- 13.5 Challenges in the Clinical Translation of Nanomedicines -- 13.6 Conclusion -- References -- 14 Biomaterials-Based Vaccination in Cancer Therapy -- 14.1 Introduction -- 14.2 Tumor-Associated Antigens -- 14.3 Vaccine Delivery -- 14.4 Dendritic Cells -- 14.5 In Vitro Generation of Dendritic Cells -- 14.6 Usage of RNA -- 14.7 RNA-Pulsed DCs as Vaccines -- 14.8 RNA Vaccines -- 14.9 Optimization of Immunotherapy -- 14.10 Cancer Treatment Through RNA Interference -- 14.11 Conclusion -- References -- Index -- End User License Agreement. |
| Record Nr. | UNINA-9910877145303321 |
Malviya Rishabha
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| Newark : , : John Wiley & Sons, Incorporated, , 2023 | ||
| Lo trovi qui: Univ. Federico II | ||
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Soft materials-based biosensing medical applications / / edited by Deepak Gupta, Milan Singh, Rishabha Malviya, Sonali Sundram
| Soft materials-based biosensing medical applications / / edited by Deepak Gupta, Milan Singh, Rishabha Malviya, Sonali Sundram |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken : , : John Wiley & Sons, Incorporated, , 2025 |
| Descrizione fisica | 1 online resource (xix, 499 pages) : illustrations |
| Soggetto topico |
Biosensors - Materials
Materials - Technological innovations Biomedical engineering Biosensing Techniques - methods Smart Materials Biocompatible Materials Biomedical Engineering |
| ISBN |
9781394214143
1394214146 9781394214730 1394214731 9781394214747 139421474X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9911018911503321 |
| Hoboken : , : John Wiley & Sons, Incorporated, , 2025 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Sustainable Green Biomaterials As Drug Delivery Systems / / edited by Rishabha Malviya, Sonali Sundram
| Sustainable Green Biomaterials As Drug Delivery Systems / / edited by Rishabha Malviya, Sonali Sundram |
| Autore | Malviya Rishabha |
| Edizione | [1st ed. 2025.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025 |
| Descrizione fisica | 1 online resource (598 pages) |
| Disciplina | 615.6 |
| Altri autori (Persone) | SundramSonali |
| Collana | Biomaterials, Bioengineering and Sustainability |
| Soggetto topico |
Drug delivery systems
Pharmacology Biomedical engineering Biomaterials Sustainability Biotechnology Drug Delivery Biomedical Engineering and Bioengineering |
| ISBN |
9783031790621
3031790626 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Sustainable Green Biomaterials in Drug delivery -- Chapter 2. Prospects of biodegradable material: sustainable and patient-centric approach in the realm of biomedical engineering -- Chapter 3. Prospects of biodegradable material: Sustainable and patient-centric approach in the realm of biomedical engineering -- Chapter 4. Probiotic Bacterial Cellulose: A Bio-mediated Nanomaterial for Health Care Applications -- Chapter 5. 3D Printing and 4D Printing: Sustainable manufacturing techniques for Green Biomaterials -- Chapter 6. Proteins as Biocompatible Material for Biomedical Applications -- Chapter 7. Graphene-based Carbonaceous Materials: A Sustainable Biomaterial for Biomedical Application -- Chapter 8. Green Approach for Synthesizing Silk Fibroin Biomaterial Scaffolds -- Chapter 9. Green Catalysts in the Synthesis of Biomaterials for Biomedical Applications -- Chapter 10. Utilisation of plant extracts for green synthesis of metallic nanoparticles -- Chapter 11. Green and sustainable synthesis of silver nanoparticles using wastes of crude drugs for traditional medicinal use in Nara, Japan -- Chapter 12. Metal Frameword in Biosensor -- Chapter 13. Cellulose, Chitin, and Chitosan Composite-Based Sustainable Biomaterials -- Chapter 14. Sustainable Synthesis of Cellulose-Derived Hydrogels for Tissue Engineering -- Chapter 15. Hydroxyapatite-Starch-Based Sustainable Biomaterials -- Chapter 16. Surfactant-free Synthesis of Metal and Metal oxide Nanomaterials: Sustainable and eco-synthesis methods. |
| Record Nr. | UNINA-9910983345303321 |
Malviya Rishabha
|
||
| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||