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The laboratory rabbit, guinea pig, hamster, and other rodents [[electronic resource] /] / edited by Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson
| The laboratory rabbit, guinea pig, hamster, and other rodents [[electronic resource] /] / edited by Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2012 |
| Descrizione fisica | 1 online resource (1289 p.) |
| Disciplina |
636.0885
636.932 |
| Altri autori (Persone) |
SuckowMark A
StevensKarla A WilsonRonald P |
| Collana | American College of Laboratory Animal Medicine series |
| Soggetto topico |
Laboratory animals
Rabbits as laboratory animals Guinea pigs as laboratory animals Hamsters as laboratory animals |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-39404-9
9786613394040 0-12-380921-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents; Copyright Page; Contents; Preface; List of Contributors; List of Reviewers; I. GENERAL; 1. Ethical Considerations and Regulatory Issues; Introduction; Ethical Concepts; Moral Theories; Descriptive Laboratory Animal Use Ethics; Ethical Principles; Respect for Life; Societal Benefit; Non-Maleficence; The Three Rs (Replacement, Reduction, and Refinement); Replacement; Reduction; Refinement; Ethical Challenges; Breeding Colonies; Genetically Modified Rodents; Cancer Research; Perinatal Animal Use
Neuroscience and Behavioral ResearchFood and Fluid Restriction; Neuroanatomic Studies; Neural Injury and Disease; Behavioral Studies; Prolonged Restraint and Anesthesia; Restraint of Awake Animals; Prolonged Studies in Anesthetized Animals; Institutional Animal Welfare Oversight; Regulations and Non-regulatory Considerations; United States Regulatory Considerations; United States Animal Welfare Act; Public Health Service Policy on Humane Care and Use of Animals; Food and Drug Administration Good Laboratory Practices; Interagency Cooperation Environmental Protection Agency Good Laboratory PracticesNon-Regulatory Considerations; Institute for Laboratory Animal Research; Guide for the Care and Use of Laboratory Animals (Guide); International Regulations, Policies, and Standards; AAALAC, International; Canada; European Union; Pacific Rim; Australia; New Zealand; Japan; South Korea; Philippines; Thailand; China; Taiwan; Singapore; Hong Kong; Conclusion; References; 2. Anesthesia and Analgesia; Pre-anesthetic Preparation; Physical Examination; Fasting; Stabilization; Regulatory Requirements; Controlled Substances; Pharmacology AnticholinergicsPhenothiazines; Benzodiazepines; Alpha2-Agonists; Systemic Analgesics; Opioids; Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); Tramadol; Gabapentin; Amantadine; Local Anesthetics; Glucocorticoids; N-Methyl-D-Aspartic Acid (NMDA) Antagonist; Ketamine; Tiletamine-Zolazepam; Propofol; Barbiturates; Inhalation Anesthetics; Anesthesia Circuits; Induction Chambers; Breathing Circuits; Vaporizer Types and Machines; Ventilators; Regulatory Monitoring Requirements; Anesthesia Waste Gas Scavenging; Anesthesia Monitoring and Support; Anesthetic Depth; Respiratory Function Cardiovascular FunctionTemperature; Fluid Therapy; Intubation; Surgical Anesthesia; Post-operative Monitoring and Pain Assessment; Pain Assessment; Post-Operative Analgesia; Post-Operative Monitoring; References; 3. Clinical Biochemistry and Hematology; Introduction; Clinical Biochemistry; Introduction; Sample Collection; Restraint; Blood Collection; Urine Collection; Carbohydrate Metabolism; Glucose; Lipid Metabolism; Cholesterol; Triglycerides; Enzymes; Alkaline Phosphatase (ALP); Alanine Aminotransferase (ALT); Aspartate Aminotransferase (AST); Lactate Dehydrogenase (LDH) Creatine Kinase (CK) |
| Record Nr. | UNINA-9910461642203321 |
| London, : Elsevier, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The laboratory rabbit, guinea pig, hamster, and other rodents [[electronic resource] /] / edited by Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson
| The laboratory rabbit, guinea pig, hamster, and other rodents [[electronic resource] /] / edited by Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2012 |
| Descrizione fisica | 1 online resource (1289 p.) |
| Disciplina |
636.0885
636.932 |
| Altri autori (Persone) |
SuckowMark A
StevensKarla A WilsonRonald P |
| Collana | American College of Laboratory Animal Medicine series |
| Soggetto topico |
Laboratory animals
Rabbits as laboratory animals Guinea pigs as laboratory animals Hamsters as laboratory animals |
| ISBN |
1-283-39404-9
9786613394040 0-12-380921-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents; Copyright Page; Contents; Preface; List of Contributors; List of Reviewers; I. GENERAL; 1. Ethical Considerations and Regulatory Issues; Introduction; Ethical Concepts; Moral Theories; Descriptive Laboratory Animal Use Ethics; Ethical Principles; Respect for Life; Societal Benefit; Non-Maleficence; The Three Rs (Replacement, Reduction, and Refinement); Replacement; Reduction; Refinement; Ethical Challenges; Breeding Colonies; Genetically Modified Rodents; Cancer Research; Perinatal Animal Use
Neuroscience and Behavioral ResearchFood and Fluid Restriction; Neuroanatomic Studies; Neural Injury and Disease; Behavioral Studies; Prolonged Restraint and Anesthesia; Restraint of Awake Animals; Prolonged Studies in Anesthetized Animals; Institutional Animal Welfare Oversight; Regulations and Non-regulatory Considerations; United States Regulatory Considerations; United States Animal Welfare Act; Public Health Service Policy on Humane Care and Use of Animals; Food and Drug Administration Good Laboratory Practices; Interagency Cooperation Environmental Protection Agency Good Laboratory PracticesNon-Regulatory Considerations; Institute for Laboratory Animal Research; Guide for the Care and Use of Laboratory Animals (Guide); International Regulations, Policies, and Standards; AAALAC, International; Canada; European Union; Pacific Rim; Australia; New Zealand; Japan; South Korea; Philippines; Thailand; China; Taiwan; Singapore; Hong Kong; Conclusion; References; 2. Anesthesia and Analgesia; Pre-anesthetic Preparation; Physical Examination; Fasting; Stabilization; Regulatory Requirements; Controlled Substances; Pharmacology AnticholinergicsPhenothiazines; Benzodiazepines; Alpha2-Agonists; Systemic Analgesics; Opioids; Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); Tramadol; Gabapentin; Amantadine; Local Anesthetics; Glucocorticoids; N-Methyl-D-Aspartic Acid (NMDA) Antagonist; Ketamine; Tiletamine-Zolazepam; Propofol; Barbiturates; Inhalation Anesthetics; Anesthesia Circuits; Induction Chambers; Breathing Circuits; Vaporizer Types and Machines; Ventilators; Regulatory Monitoring Requirements; Anesthesia Waste Gas Scavenging; Anesthesia Monitoring and Support; Anesthetic Depth; Respiratory Function Cardiovascular FunctionTemperature; Fluid Therapy; Intubation; Surgical Anesthesia; Post-operative Monitoring and Pain Assessment; Pain Assessment; Post-Operative Analgesia; Post-Operative Monitoring; References; 3. Clinical Biochemistry and Hematology; Introduction; Clinical Biochemistry; Introduction; Sample Collection; Restraint; Blood Collection; Urine Collection; Carbohydrate Metabolism; Glucose; Lipid Metabolism; Cholesterol; Triglycerides; Enzymes; Alkaline Phosphatase (ALP); Alanine Aminotransferase (ALT); Aspartate Aminotransferase (AST); Lactate Dehydrogenase (LDH) Creatine Kinase (CK) |
| Record Nr. | UNINA-9910789888503321 |
| London, : Elsevier, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The laboratory rabbit, guinea pig, hamster, and other rodents [[electronic resource] /] / edited by Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson
| The laboratory rabbit, guinea pig, hamster, and other rodents [[electronic resource] /] / edited by Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2012 |
| Descrizione fisica | 1 online resource (1289 p.) |
| Disciplina |
636.0885
636.932 |
| Altri autori (Persone) |
SuckowMark A
StevensKarla A WilsonRonald P |
| Collana | American College of Laboratory Animal Medicine series |
| Soggetto topico |
Laboratory animals
Rabbits as laboratory animals Guinea pigs as laboratory animals Hamsters as laboratory animals |
| ISBN |
1-283-39404-9
9786613394040 0-12-380921-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents; Copyright Page; Contents; Preface; List of Contributors; List of Reviewers; I. GENERAL; 1. Ethical Considerations and Regulatory Issues; Introduction; Ethical Concepts; Moral Theories; Descriptive Laboratory Animal Use Ethics; Ethical Principles; Respect for Life; Societal Benefit; Non-Maleficence; The Three Rs (Replacement, Reduction, and Refinement); Replacement; Reduction; Refinement; Ethical Challenges; Breeding Colonies; Genetically Modified Rodents; Cancer Research; Perinatal Animal Use
Neuroscience and Behavioral ResearchFood and Fluid Restriction; Neuroanatomic Studies; Neural Injury and Disease; Behavioral Studies; Prolonged Restraint and Anesthesia; Restraint of Awake Animals; Prolonged Studies in Anesthetized Animals; Institutional Animal Welfare Oversight; Regulations and Non-regulatory Considerations; United States Regulatory Considerations; United States Animal Welfare Act; Public Health Service Policy on Humane Care and Use of Animals; Food and Drug Administration Good Laboratory Practices; Interagency Cooperation Environmental Protection Agency Good Laboratory PracticesNon-Regulatory Considerations; Institute for Laboratory Animal Research; Guide for the Care and Use of Laboratory Animals (Guide); International Regulations, Policies, and Standards; AAALAC, International; Canada; European Union; Pacific Rim; Australia; New Zealand; Japan; South Korea; Philippines; Thailand; China; Taiwan; Singapore; Hong Kong; Conclusion; References; 2. Anesthesia and Analgesia; Pre-anesthetic Preparation; Physical Examination; Fasting; Stabilization; Regulatory Requirements; Controlled Substances; Pharmacology AnticholinergicsPhenothiazines; Benzodiazepines; Alpha2-Agonists; Systemic Analgesics; Opioids; Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); Tramadol; Gabapentin; Amantadine; Local Anesthetics; Glucocorticoids; N-Methyl-D-Aspartic Acid (NMDA) Antagonist; Ketamine; Tiletamine-Zolazepam; Propofol; Barbiturates; Inhalation Anesthetics; Anesthesia Circuits; Induction Chambers; Breathing Circuits; Vaporizer Types and Machines; Ventilators; Regulatory Monitoring Requirements; Anesthesia Waste Gas Scavenging; Anesthesia Monitoring and Support; Anesthetic Depth; Respiratory Function Cardiovascular FunctionTemperature; Fluid Therapy; Intubation; Surgical Anesthesia; Post-operative Monitoring and Pain Assessment; Pain Assessment; Post-Operative Analgesia; Post-Operative Monitoring; References; 3. Clinical Biochemistry and Hematology; Introduction; Clinical Biochemistry; Introduction; Sample Collection; Restraint; Blood Collection; Urine Collection; Carbohydrate Metabolism; Glucose; Lipid Metabolism; Cholesterol; Triglycerides; Enzymes; Alkaline Phosphatase (ALP); Alanine Aminotransferase (ALT); Aspartate Aminotransferase (AST); Lactate Dehydrogenase (LDH) Creatine Kinase (CK) |
| Record Nr. | UNINA-9910823388403321 |
| London, : Elsevier, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin
| The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, c2006 |
| Descrizione fisica | 1 online resource (929 p.) |
| Disciplina | 616/.02733 |
| Altri autori (Persone) |
SuckowMark A
WeisbrothSteven H FranklinCraig L |
| Collana | American College of Laboratory Animal Medicine series |
| Soggetto topico | Rats as laboratory animals |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-62843-X
9786610628438 0-08-045432-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front cover; Title page; Copyright page; Table of contents; List of Contributors; Preface; Foreword; List of Reviewers for Chapters in This Volume; 1. Historical Foundations; I. ORIGIN OF THE LABORATORY RAT; A. Earliest Records; B. Earliest Experiments; II. THE WISTAR INSTITUTE; A. Background; B. Milton J. Greenman; C. Henry H. Donaldson; D. Contributions of Donaldson's Colleagues; E. The Wistar Rat Colony; F. Wistar under Edmund Farris; G. The Modern Era at Wistar; III. BEHAVIORAL RESEARCH; A. Doctoral Students at Clark University; B. Watson and Meyer; IV. NUTRITION AND BIOCHEMISTRY
A. McCollum and the McCollum-Pratt InstituteB. Osborne and Mendel; C. Henry C. Sherman; V. ENDOCRINOLOGY AND REPRODUCTIVE PHYSIOLOGY; A. Long and Evans; B. Evans and The Institute of Experimental Biology; VI. GENETICS; A. Castle and The Bussey Institution of Harvard; B. Castle's Second Career; VII. CANCER RESEARCH INSTITUTES; A. The Crocker Institute of Cancer Research; B. The Detroit Institute for Cancer Research; C. The University of Miami and Papanicolaou Cancer Research Institute; VIII. OTHER STOCKS OF RATS; A. Sprague-Dawley; B. Albany Strain C. Hunt's Caries-Susceptible and Caries-Resistant StrainsD. The Oldest Rat Stock and the PAR/Lou Strain; IX. GENEALOGY OF MAJOR RAT STOCKS AND STRAINS; X. GNOTOBIOLOGY: RATS WITHOUT MICROFLORA; A. Gustafsson at the University of Lund; B. Reyniers and The Lobund Institute; XI. SECURING THE FOUNDATIONS; A. Funding: Role of The National Institutes of Health; B. Health: Eliminating Pathogens and Nutrients as Variables; C. Genetics: Repositories and Standards; D. Information: Dissemination and Exchange; XII. EPILOGUE; ACKNOWLEDGMENTS; REFERENCES; 2. Ethical and Legal Perspectives; I. INTRODUCTION II. ETHICAL CONSIDERATIONSA. The Principles of Reduction, Replacement, and Refinement; B. Ethical Concepts and Legal Implementation; III. ENVIRONMENTAL ENRICHMENT FOR LABORATORY RATS; A. Contributions of Russell and Burch; B. Enrichment Goals; C. Testing Methods; D. Cage Size, Design and Flooring; E. Bedding, Nesting Material and Nest Boxes; F. Inanimate Objects (Toys andTubes); G. Single versus Group Housing; IV. LEGALAND REGULATORY ISSUES; A. U.S. Legislation, Policies, and Guidelines Governing Laboratory Rats; B. Reduction of Regulatory Burden in Laboratory Animal Welfare C. U.S. Animal WelfareAct ( 1966-1990)D. USDA Regulations Related to Rats, Mice and Birds; REFERENCES; 3. Taxonomy and Stocks and Strains; I. INTRODUCTION; II. TAXONOMY AND GEOGRAPHICAL DISTRIBUTION; III. ADAPTATION TO THE LABORATORY; IV. STOCKS AND STRAINS OF LABORATORY RATS; A. Outbred Stocks; B. Inbred Strains; V. NOMENCLATURE; A. Nomenclature Rules for Outbred Stocks; B. Nomenclature Rules for Inbred Strains; VI. SUMMARY; REFERENCES; 4. Morphophysiology; I. INTRODUCTION; II. GENERAL APPEARANCE; A. Head and Body; B. External Reproductive Genitalia; C. Skeletal Structure; D. Musculature E. Superficial Glands of the Head and Neck |
| Record Nr. | UNINA-9910458460903321 |
| Amsterdam ; ; Boston, : Elsevier, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin
| The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, c2006 |
| Descrizione fisica | 1 online resource (929 p.) |
| Disciplina | 616/.02733 |
| Altri autori (Persone) |
SuckowMark A
WeisbrothSteven H FranklinCraig L |
| Collana | American College of Laboratory Animal Medicine series |
| Soggetto topico | Rats as laboratory animals |
| ISBN |
1-280-62843-X
9786610628438 0-08-045432-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front cover; Title page; Copyright page; Table of contents; List of Contributors; Preface; Foreword; List of Reviewers for Chapters in This Volume; 1. Historical Foundations; I. ORIGIN OF THE LABORATORY RAT; A. Earliest Records; B. Earliest Experiments; II. THE WISTAR INSTITUTE; A. Background; B. Milton J. Greenman; C. Henry H. Donaldson; D. Contributions of Donaldson's Colleagues; E. The Wistar Rat Colony; F. Wistar under Edmund Farris; G. The Modern Era at Wistar; III. BEHAVIORAL RESEARCH; A. Doctoral Students at Clark University; B. Watson and Meyer; IV. NUTRITION AND BIOCHEMISTRY
A. McCollum and the McCollum-Pratt InstituteB. Osborne and Mendel; C. Henry C. Sherman; V. ENDOCRINOLOGY AND REPRODUCTIVE PHYSIOLOGY; A. Long and Evans; B. Evans and The Institute of Experimental Biology; VI. GENETICS; A. Castle and The Bussey Institution of Harvard; B. Castle's Second Career; VII. CANCER RESEARCH INSTITUTES; A. The Crocker Institute of Cancer Research; B. The Detroit Institute for Cancer Research; C. The University of Miami and Papanicolaou Cancer Research Institute; VIII. OTHER STOCKS OF RATS; A. Sprague-Dawley; B. Albany Strain C. Hunt's Caries-Susceptible and Caries-Resistant StrainsD. The Oldest Rat Stock and the PAR/Lou Strain; IX. GENEALOGY OF MAJOR RAT STOCKS AND STRAINS; X. GNOTOBIOLOGY: RATS WITHOUT MICROFLORA; A. Gustafsson at the University of Lund; B. Reyniers and The Lobund Institute; XI. SECURING THE FOUNDATIONS; A. Funding: Role of The National Institutes of Health; B. Health: Eliminating Pathogens and Nutrients as Variables; C. Genetics: Repositories and Standards; D. Information: Dissemination and Exchange; XII. EPILOGUE; ACKNOWLEDGMENTS; REFERENCES; 2. Ethical and Legal Perspectives; I. INTRODUCTION II. ETHICAL CONSIDERATIONSA. The Principles of Reduction, Replacement, and Refinement; B. Ethical Concepts and Legal Implementation; III. ENVIRONMENTAL ENRICHMENT FOR LABORATORY RATS; A. Contributions of Russell and Burch; B. Enrichment Goals; C. Testing Methods; D. Cage Size, Design and Flooring; E. Bedding, Nesting Material and Nest Boxes; F. Inanimate Objects (Toys andTubes); G. Single versus Group Housing; IV. LEGALAND REGULATORY ISSUES; A. U.S. Legislation, Policies, and Guidelines Governing Laboratory Rats; B. Reduction of Regulatory Burden in Laboratory Animal Welfare C. U.S. Animal WelfareAct ( 1966-1990)D. USDA Regulations Related to Rats, Mice and Birds; REFERENCES; 3. Taxonomy and Stocks and Strains; I. INTRODUCTION; II. TAXONOMY AND GEOGRAPHICAL DISTRIBUTION; III. ADAPTATION TO THE LABORATORY; IV. STOCKS AND STRAINS OF LABORATORY RATS; A. Outbred Stocks; B. Inbred Strains; V. NOMENCLATURE; A. Nomenclature Rules for Outbred Stocks; B. Nomenclature Rules for Inbred Strains; VI. SUMMARY; REFERENCES; 4. Morphophysiology; I. INTRODUCTION; II. GENERAL APPEARANCE; A. Head and Body; B. External Reproductive Genitalia; C. Skeletal Structure; D. Musculature E. Superficial Glands of the Head and Neck |
| Record Nr. | UNINA-9910784547303321 |
| Amsterdam ; ; Boston, : Elsevier, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin
| The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, c2006 |
| Descrizione fisica | 1 online resource (929 p.) |
| Disciplina | 616/.02733 |
| Altri autori (Persone) |
SuckowMark A
WeisbrothSteven H FranklinCraig L |
| Collana | American College of Laboratory Animal Medicine series |
| Soggetto topico | Rats as laboratory animals |
| ISBN |
1-280-62843-X
9786610628438 0-08-045432-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front cover; Title page; Copyright page; Table of contents; List of Contributors; Preface; Foreword; List of Reviewers for Chapters in This Volume; 1. Historical Foundations; I. ORIGIN OF THE LABORATORY RAT; A. Earliest Records; B. Earliest Experiments; II. THE WISTAR INSTITUTE; A. Background; B. Milton J. Greenman; C. Henry H. Donaldson; D. Contributions of Donaldson's Colleagues; E. The Wistar Rat Colony; F. Wistar under Edmund Farris; G. The Modern Era at Wistar; III. BEHAVIORAL RESEARCH; A. Doctoral Students at Clark University; B. Watson and Meyer; IV. NUTRITION AND BIOCHEMISTRY
A. McCollum and the McCollum-Pratt InstituteB. Osborne and Mendel; C. Henry C. Sherman; V. ENDOCRINOLOGY AND REPRODUCTIVE PHYSIOLOGY; A. Long and Evans; B. Evans and The Institute of Experimental Biology; VI. GENETICS; A. Castle and The Bussey Institution of Harvard; B. Castle's Second Career; VII. CANCER RESEARCH INSTITUTES; A. The Crocker Institute of Cancer Research; B. The Detroit Institute for Cancer Research; C. The University of Miami and Papanicolaou Cancer Research Institute; VIII. OTHER STOCKS OF RATS; A. Sprague-Dawley; B. Albany Strain C. Hunt's Caries-Susceptible and Caries-Resistant StrainsD. The Oldest Rat Stock and the PAR/Lou Strain; IX. GENEALOGY OF MAJOR RAT STOCKS AND STRAINS; X. GNOTOBIOLOGY: RATS WITHOUT MICROFLORA; A. Gustafsson at the University of Lund; B. Reyniers and The Lobund Institute; XI. SECURING THE FOUNDATIONS; A. Funding: Role of The National Institutes of Health; B. Health: Eliminating Pathogens and Nutrients as Variables; C. Genetics: Repositories and Standards; D. Information: Dissemination and Exchange; XII. EPILOGUE; ACKNOWLEDGMENTS; REFERENCES; 2. Ethical and Legal Perspectives; I. INTRODUCTION II. ETHICAL CONSIDERATIONSA. The Principles of Reduction, Replacement, and Refinement; B. Ethical Concepts and Legal Implementation; III. ENVIRONMENTAL ENRICHMENT FOR LABORATORY RATS; A. Contributions of Russell and Burch; B. Enrichment Goals; C. Testing Methods; D. Cage Size, Design and Flooring; E. Bedding, Nesting Material and Nest Boxes; F. Inanimate Objects (Toys andTubes); G. Single versus Group Housing; IV. LEGALAND REGULATORY ISSUES; A. U.S. Legislation, Policies, and Guidelines Governing Laboratory Rats; B. Reduction of Regulatory Burden in Laboratory Animal Welfare C. U.S. Animal WelfareAct ( 1966-1990)D. USDA Regulations Related to Rats, Mice and Birds; REFERENCES; 3. Taxonomy and Stocks and Strains; I. INTRODUCTION; II. TAXONOMY AND GEOGRAPHICAL DISTRIBUTION; III. ADAPTATION TO THE LABORATORY; IV. STOCKS AND STRAINS OF LABORATORY RATS; A. Outbred Stocks; B. Inbred Strains; V. NOMENCLATURE; A. Nomenclature Rules for Outbred Stocks; B. Nomenclature Rules for Inbred Strains; VI. SUMMARY; REFERENCES; 4. Morphophysiology; I. INTRODUCTION; II. GENERAL APPEARANCE; A. Head and Body; B. External Reproductive Genitalia; C. Skeletal Structure; D. Musculature E. Superficial Glands of the Head and Neck |
| Record Nr. | UNINA-9910826101003321 |
| Amsterdam ; ; Boston, : Elsevier, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||